Connect public, paid and private patent data with Google Patents Public Datasets

Mouthwash

Download PDF

Info

Publication number
US2527686A
US2527686A US63725745A US2527686A US 2527686 A US2527686 A US 2527686A US 63725745 A US63725745 A US 63725745A US 2527686 A US2527686 A US 2527686A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
fluoride
grains
employed
invention
mouth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
Max H Sandberg
Original Assignee
Max H Sandberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/19Cosmetics or similar toilet preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • A61K8/21Fluorides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/19Cosmetics or similar toilet preparations characterised by the composition containing inorganic ingredients
    • A61K8/27Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toilet preparations characterised by the composition containing organic compounds containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/96Cosmetics or similar toilet preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toilet preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof

Description

Patented Oct. 31 1950 MOUTHWASH Max H. Sandberg, MattapamlMass.

Application December 26, 1945, Serial No. 637,257

Claims.

This invention relates to mouth washes and particularly to compositions of this character which may be utilized to have a very eflicacious effect against dental caries.

Among the objects of the present invention is the production of compositions which can be utilized as mouth washes to prevent development of cavities in teeth.

Other objects and advantages will appear from the more detailed description set forth below, it being understood that such more detailed description is given by way of illustration and explanation only, and not by way of limitation since various changes therein may be made by those skilled in the art without departing from the scope and spirit of the present invention.

In accordance with the present invention it has been found that water soluble fluorides particularly of the alkali metals may be utilized in proper vehicles as a mouth wash or for related purposes, in limited concentrations in such mouth washes, to have a beneficial effect against development of cavities in teeth. The fluorides employed are desirably alkali metal fluorides of which ammonium fluoride or ammonium bifluoride has been found to be the best, while the sodium fluoride can be utilized. Potassium fluoride is the less efficacious. The fluoride is utilized in the vehicle which enables it to be carried into the enamel rods.

In such composition there is employed papain which digests proteins and malt or diastase such as takadiastase which digests starches. These ferments may be employed in such composition and do not interfere with each other. Other ferments cannot be employed in lieu of the particular ferments mentioned above and those set forth, namely, the papain and malt must be employed to give the most desirable results in accordance with the present invention. Such ferments together with the fluorides are desirably used in an aqueous composition which also contains zinc chloride and formaldehyde, as for example, commercial formalin. The most desirable proportions have been found to be 1 mole of fluoride to 1 mole of zinc chloride to 1 mole of formaldehyde but other ratios may be employed. The amount of fluoride present should be carefully controlled and should lie within about to 30 grains per gallon of the final solution. Less than 15 grains per gallon does not give any substantial effect while more than 30 grains tends to give a mottling effect. The preferred range is from 15 to 25 grains per gallon.

The stated ingredients are desirably used in an aqueous vehicle and since zinc chloride has a tendency to decompose in the presence of water, a water-soluble non-toxic alcohol may desirably be added to prevent this efiect. Ethyl alcohol is preferred, isopropyl and similar alcohols may be employed. Variation in the amount of alcohol and water proportions may, of course, be employed, but less alcohol than that indicated tends to give some undesirable feeling on the gums.

Flavoring components as desired may be employed such as the flavoring oils like oil of cassia, oil of cloves, and saccharin may be included in small amounts. The composition may be colored with any suitable dye. If desired to impart a Wintergreen aroma, this may be done by permitting the composition to stand within an atmosphere containing such oil of Wintergreen for a period of about one week.

The following is a preferred formula:

Parts Zinc chloride 2 Formalin (commercial) .5

Papain -l 100 Malt 100 The flavoring ingredients and vehicle components include:

Parts Oil of cassia 1.5 Oil of cloves .5

Saccharin .5 Ethyl alcohol 40 'Water 1000 The materials may be mixed in any desired way and the fluoride added to produce the stated concentration of from 15 to grains per gallon of solution, desirably 25 grains of sodium or ammonium fluoride being added for this purpose. While the fluoride may be incorporated together with all of the other ingredients, it is desirable to add it as the final component. The parts given in this example are by weight.

Compositions produced in accordance with the present invention have been proven to be a specific in preventing the formation of dental caries. This invention being a prophylactic only, does not have any action .on dental caries that are in active progress.

Having thus set forth my invention, I claim:

1. A mouth Wash containing zinc chloride, formaldehyde, papain, malt and water, and an alkali metal fluoride in an amount of from 15 to 30 grains per gallon of solution.

2. A composition as set forth inclaim 1,-in which the fluoride is ammonium fluoride.

(3. A composition as set forth in claim 1, in which the fluoride is sodium fluoride.

4. A mouth wash as set forth in claim 1 containing an amount of a non-toxic aliphatic alcohol sufiicient to prevent decomposition of the zinc chloride.

5. A mouth wash containing the following components in parts by weight: zinc chloride 2, formalin .5, papain 100, malt 100, ethyl alcohol 40, water 1000, and an alkali metal fluoride in an amount of 25 grains per gallon of solution.

MAX H. SANDBERG.

REFERENCES CITED The following references are of record in the file of this patent:

Number 0 Number 4 UNITED STATES PATENTS Name Date Monroe Dec. 29, 1925 Cross Jan. 16, 1934 FOREIGN PATENTS Country Date France Dec. 1, 1910 Great Britain of 1914 Austria Apr. 10, 1922 Great Britain Apr. 13, 1942

Claims (1)

1. A MOUTH WASH CONTAINING ZINC CHLORIDE, FORMALDEHYDE, PAPAIN, MALT AND WATER, AND AN ALKALI METAL FLUORIDE IN AN AMOUNT OF FROM 15 TO 30 GRAINS PER GALLON OF SOLUTION.
US2527686A 1945-12-26 1945-12-26 Mouthwash Expired - Lifetime US2527686A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US2527686A US2527686A (en) 1945-12-26 1945-12-26 Mouthwash

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2527686A US2527686A (en) 1945-12-26 1945-12-26 Mouthwash

Publications (1)

Publication Number Publication Date
US2527686A true US2527686A (en) 1950-10-31

Family

ID=24555186

Family Applications (1)

Application Number Title Priority Date Filing Date
US2527686A Expired - Lifetime US2527686A (en) 1945-12-26 1945-12-26 Mouthwash

Country Status (1)

Country Link
US (1) US2527686A (en)

Cited By (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2829086A (en) * 1954-09-21 1958-04-01 Colgate Palmolive Co Dental preparations comprising higher aliphatic perfluorinated acid compounds
US2913373A (en) * 1957-08-28 1959-11-17 Walter S Weisz Fluoride mouth wash composition
US3072532A (en) * 1958-11-04 1963-01-08 Innerfield Irving Administration of enzymic composition
US3852432A (en) * 1971-01-18 1974-12-03 Department Of Health Education Diagnostic device and method of treatment
US4082841A (en) * 1975-10-10 1978-04-04 Lever Brothers Company Dentifrice
US4096241A (en) * 1975-06-24 1978-06-20 Ed. Geistlich Sohne A.G. Fur Chemische Industrie Tooth preparations
US4152418A (en) * 1970-04-01 1979-05-01 Lever Brothers Company Zinc and enzyme mouthwash and mouthwash concentrate for reducing dental plaque and calculus formation
US4339432A (en) * 1979-06-20 1982-07-13 Lever Brothers Company Oral mouthwash containing zinc and glycine
EP0075446A2 (en) * 1981-09-17 1983-03-30 Johnson & Johnson Products Inc. Anticaries composition
US4416867A (en) * 1979-06-20 1983-11-22 Lever Brothers Company Oral compositions
US4469674A (en) * 1981-09-03 1984-09-04 Richardson-Vicks Inc. Stable oral compositions containing zinc and fluoride compounds
US4473550A (en) * 1981-01-16 1984-09-25 Rosenbaum Robert S Bactericidal compositions and methods
US4476108A (en) * 1981-01-16 1984-10-09 Kessler Jack H Bactericidal method
US4588586A (en) * 1983-01-03 1986-05-13 Kessler Jack H Method for disinfecting a contact lens
US4847089A (en) * 1986-07-16 1989-07-11 David N. Kramer Cleansing and distinfecting compositions, including bleaching agents, and sponges and other applicators incorporating the same
USRE33465E (en) * 1981-07-31 1990-11-27 Method for reducing the duration of the common cold
US5002970A (en) * 1981-07-31 1991-03-26 Eby Iii George A Flavor masked ionizable zinc compositions for oral absorption
US5405836A (en) * 1993-03-02 1995-04-11 Nabisco, Inc. Pet foods with water-soluble zinc compound coating for controlling malodorous breath
WO1997040812A1 (en) * 1996-04-26 1997-11-06 Warner-Lambert Company Enhanced zinc containing oral composition
US20070293466A1 (en) * 2004-11-03 2007-12-20 Thompson Robert C Antimicrobial Chelates
US20080152601A1 (en) * 2002-08-28 2008-06-26 Colgate-Palmolive Company Dual Component Dental Composition Containing Enzyme
US20080213195A1 (en) * 2002-05-10 2008-09-04 Szeles Lori H Antibacterial Dentifrice Exhibiting Antiplaque and Breath Freshening Properties
US7687650B2 (en) 2006-02-03 2010-03-30 Jr Chem, Llc Chemical compositions and methods of making them
US7867522B2 (en) 2006-09-28 2011-01-11 Jr Chem, Llc Method of wound/burn healing using copper-zinc compositions
US7897800B2 (en) 2006-02-03 2011-03-01 Jr Chem, Llc Chemical compositions and methods of making them
US7927614B2 (en) 2006-02-03 2011-04-19 Jr Chem, Llc Anti-aging treatment using copper and zinc compositions
US8273791B2 (en) 2008-01-04 2012-09-25 Jr Chem, Llc Compositions, kits and regimens for the treatment of skin, especially décolletage
WO2014193251A1 (en) 2013-05-30 2014-12-04 Warszawski Uniwersytet Medyczny Preparation for maintenance of oral cavity hygiene and prevention of plaque formation
US8952057B2 (en) 2011-01-11 2015-02-10 Jr Chem, Llc Compositions for anorectal use and methods for treating anorectal disorders
US9427397B2 (en) 2009-01-23 2016-08-30 Obagi Medical Products, Inc. Rosacea treatments and kits for performing them
US9498421B2 (en) 2012-12-19 2016-11-22 Colgate-Palmolive Company Two component compositions containing tetrabasic zinc-amino acid halide complexes and cysteine
US9504858B2 (en) 2012-12-19 2016-11-29 Colgate-Palmolive Company Zinc amino acid halide complex with cysteine
US9572756B2 (en) 2012-12-19 2017-02-21 Colgate-Palmolive Company Teeth whitening methods, visually perceptible signals and compositions therefor
US9675823B2 (en) 2012-12-19 2017-06-13 Colgate-Palmolive Company Two component compositions containing zinc amino acid halide complexes and cysteine
US9750670B2 (en) 2012-12-19 2017-09-05 Colgate-Palmolive Company Zinc amino acid complex with cysteine
US9757316B2 (en) 2012-12-19 2017-09-12 Colgate-Palmolive Company Zinc-lysine complex
US9763865B2 (en) 2012-12-19 2017-09-19 Colgate-Palmolive Company Oral gel comprising zinc-amino acid complex
US9775792B2 (en) 2012-12-19 2017-10-03 Colgate-Palmolive Company Oral care products comprising a tetrabasic zinc-amino acid-halide complex
US9827177B2 (en) 2012-12-19 2017-11-28 Colgate-Palmolive Company Antiperspirant products with protein and antiperspirant salts
US9861563B2 (en) 2012-12-19 2018-01-09 Colgate-Palmolive Company Oral care products comprising tetrabasic zinc chloride and trimethylglycine

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR420705A (en) * 1910-09-06 1911-02-06 Benedict Kritchewsky depleting chemicals dental calculus
GB191403034A (en) * 1914-02-05 1915-02-05 Cecil Rudolph Lidgey Improvements in or relating to Dentifrices.
US1567974A (en) * 1923-06-01 1925-12-29 Monroe Charles Wesley Treatment of pyorrhea
US1943856A (en) * 1929-07-10 1934-01-16 Silica Products Company Dental preparation
GB544405A (en) * 1939-06-28 1942-04-13 James Howard Cummings An improved proteolytic dentifrice

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR420705A (en) * 1910-09-06 1911-02-06 Benedict Kritchewsky depleting chemicals dental calculus
GB191403034A (en) * 1914-02-05 1915-02-05 Cecil Rudolph Lidgey Improvements in or relating to Dentifrices.
US1567974A (en) * 1923-06-01 1925-12-29 Monroe Charles Wesley Treatment of pyorrhea
US1943856A (en) * 1929-07-10 1934-01-16 Silica Products Company Dental preparation
GB544405A (en) * 1939-06-28 1942-04-13 James Howard Cummings An improved proteolytic dentifrice

Cited By (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2829086A (en) * 1954-09-21 1958-04-01 Colgate Palmolive Co Dental preparations comprising higher aliphatic perfluorinated acid compounds
US2913373A (en) * 1957-08-28 1959-11-17 Walter S Weisz Fluoride mouth wash composition
US3072532A (en) * 1958-11-04 1963-01-08 Innerfield Irving Administration of enzymic composition
US4152418A (en) * 1970-04-01 1979-05-01 Lever Brothers Company Zinc and enzyme mouthwash and mouthwash concentrate for reducing dental plaque and calculus formation
US3852432A (en) * 1971-01-18 1974-12-03 Department Of Health Education Diagnostic device and method of treatment
US4096241A (en) * 1975-06-24 1978-06-20 Ed. Geistlich Sohne A.G. Fur Chemische Industrie Tooth preparations
US4082841A (en) * 1975-10-10 1978-04-04 Lever Brothers Company Dentifrice
US4416867A (en) * 1979-06-20 1983-11-22 Lever Brothers Company Oral compositions
US4339432A (en) * 1979-06-20 1982-07-13 Lever Brothers Company Oral mouthwash containing zinc and glycine
US4476108A (en) * 1981-01-16 1984-10-09 Kessler Jack H Bactericidal method
US4473550A (en) * 1981-01-16 1984-09-25 Rosenbaum Robert S Bactericidal compositions and methods
USRE33465E (en) * 1981-07-31 1990-11-27 Method for reducing the duration of the common cold
US5002970A (en) * 1981-07-31 1991-03-26 Eby Iii George A Flavor masked ionizable zinc compositions for oral absorption
US4469674A (en) * 1981-09-03 1984-09-04 Richardson-Vicks Inc. Stable oral compositions containing zinc and fluoride compounds
EP0075446A3 (en) * 1981-09-17 1984-07-11 Johnson & Johnson Products Inc. Anticaries composition
EP0075446A2 (en) * 1981-09-17 1983-03-30 Johnson & Johnson Products Inc. Anticaries composition
US4588586A (en) * 1983-01-03 1986-05-13 Kessler Jack H Method for disinfecting a contact lens
US4847089A (en) * 1986-07-16 1989-07-11 David N. Kramer Cleansing and distinfecting compositions, including bleaching agents, and sponges and other applicators incorporating the same
US5405836A (en) * 1993-03-02 1995-04-11 Nabisco, Inc. Pet foods with water-soluble zinc compound coating for controlling malodorous breath
WO1997040812A1 (en) * 1996-04-26 1997-11-06 Warner-Lambert Company Enhanced zinc containing oral composition
US7939306B2 (en) 2002-05-10 2011-05-10 Colgate-Palmolive Company Antibacterial dentifrice exhibiting antiplaque and breath freshening properties
US20080213195A1 (en) * 2002-05-10 2008-09-04 Szeles Lori H Antibacterial Dentifrice Exhibiting Antiplaque and Breath Freshening Properties
US20100266514A9 (en) * 2002-08-28 2010-10-21 Colgate-Palmolive Company Dual Component Dental Composition Containing Enzyme
US20080152601A1 (en) * 2002-08-28 2008-06-26 Colgate-Palmolive Company Dual Component Dental Composition Containing Enzyme
EP2172187A1 (en) 2002-08-28 2010-04-07 Colgate-Palmolive Company Dual component dental composition containing enzyme
US20070293466A1 (en) * 2004-11-03 2007-12-20 Thompson Robert C Antimicrobial Chelates
US7582418B2 (en) 2004-11-03 2009-09-01 Albion Laboratories, Inc. Antimicrobial chelates
US7897800B2 (en) 2006-02-03 2011-03-01 Jr Chem, Llc Chemical compositions and methods of making them
US7927614B2 (en) 2006-02-03 2011-04-19 Jr Chem, Llc Anti-aging treatment using copper and zinc compositions
US7687650B2 (en) 2006-02-03 2010-03-30 Jr Chem, Llc Chemical compositions and methods of making them
US8148563B2 (en) 2006-02-03 2012-04-03 Jr Chem, Llc Chemical compositions and methods of making them
US7867522B2 (en) 2006-09-28 2011-01-11 Jr Chem, Llc Method of wound/burn healing using copper-zinc compositions
US8273791B2 (en) 2008-01-04 2012-09-25 Jr Chem, Llc Compositions, kits and regimens for the treatment of skin, especially décolletage
US8505730B2 (en) 2008-01-04 2013-08-13 Jr Chem, Llc Compositions, kits and regimens for the treatment of skin, especially décolletage
US9427397B2 (en) 2009-01-23 2016-08-30 Obagi Medical Products, Inc. Rosacea treatments and kits for performing them
US8952057B2 (en) 2011-01-11 2015-02-10 Jr Chem, Llc Compositions for anorectal use and methods for treating anorectal disorders
US9498421B2 (en) 2012-12-19 2016-11-22 Colgate-Palmolive Company Two component compositions containing tetrabasic zinc-amino acid halide complexes and cysteine
US9861563B2 (en) 2012-12-19 2018-01-09 Colgate-Palmolive Company Oral care products comprising tetrabasic zinc chloride and trimethylglycine
US9504858B2 (en) 2012-12-19 2016-11-29 Colgate-Palmolive Company Zinc amino acid halide complex with cysteine
US9572756B2 (en) 2012-12-19 2017-02-21 Colgate-Palmolive Company Teeth whitening methods, visually perceptible signals and compositions therefor
US9675823B2 (en) 2012-12-19 2017-06-13 Colgate-Palmolive Company Two component compositions containing zinc amino acid halide complexes and cysteine
US9827177B2 (en) 2012-12-19 2017-11-28 Colgate-Palmolive Company Antiperspirant products with protein and antiperspirant salts
US9757316B2 (en) 2012-12-19 2017-09-12 Colgate-Palmolive Company Zinc-lysine complex
US9763865B2 (en) 2012-12-19 2017-09-19 Colgate-Palmolive Company Oral gel comprising zinc-amino acid complex
US9775792B2 (en) 2012-12-19 2017-10-03 Colgate-Palmolive Company Oral care products comprising a tetrabasic zinc-amino acid-halide complex
US9750670B2 (en) 2012-12-19 2017-09-05 Colgate-Palmolive Company Zinc amino acid complex with cysteine
WO2014193251A1 (en) 2013-05-30 2014-12-04 Warszawski Uniwersytet Medyczny Preparation for maintenance of oral cavity hygiene and prevention of plaque formation

Similar Documents

Publication Publication Date Title
US3431208A (en) Denture spray
US3699221A (en) Dental preparations
US3122483A (en) Strontium ion toothpaste
US3337412A (en) Topical fluoride-phosphate compositions and method
US4335102A (en) Oral composition for caries prophylaxis
US3981681A (en) Depilatory formulation
US4180467A (en) Stable denture soak product
US4358437A (en) Compositions
US3903252A (en) Dental disclosing compositions and the method of making and using the same
US5041280A (en) Toothpaste composition for stain removal
US2890987A (en) Stick-form astringent compositions
US2876167A (en) Fluoride dentifrice stabilized by a water-soluble acid phosphate compound
US5756074A (en) Compositions based on an abrasive system and on a surfactant system
US4290904A (en) Transparent soap
US4362639A (en) Cleanser with improved afterodor and tarnish resistance
US4684517A (en) Mouthrinse composition containing hydrogen peroxide and fluoride
US2979465A (en) Cream shampoo
US4130638A (en) Mouthwash compositions
US3957967A (en) Agent for the care and the cleaning of teeth and dentures
US4583986A (en) Catalyzed bismuth dye system for human hair
US4759924A (en) Cosmetic sticks
US4638823A (en) Fluoride-coated dental floss
US3137632A (en) Chlorophyll dentifrice compositions
US4980152A (en) Oral preparation
US4431631A (en) Aqueous oral solution