US2432946A - Apparatus for the use of medicinal aerosols - Google Patents

Apparatus for the use of medicinal aerosols Download PDF

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Publication number
US2432946A
US2432946A US661187A US66118746A US2432946A US 2432946 A US2432946 A US 2432946A US 661187 A US661187 A US 661187A US 66118746 A US66118746 A US 66118746A US 2432946 A US2432946 A US 2432946A
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aerosols
jar
tube
medicinal
inhalation
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Expired - Lifetime
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US661187A
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Theunissen Francois Jean Marie
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TECO SA
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TECO SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0015—Details of inhalators; Constructional features thereof with inhalation check valves located upstream of the dispenser, i.e. not traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016—Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0018—Details of inhalators; Constructional features thereof with exhalation check valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/21—Mixing gases with liquids by introducing liquids into gaseous media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type

Definitions

  • the presentinvention has for its object to pro vide an apparatus permittingthe colle'ctibnv of. aerosols'in quantity appropriate to the object in View, as also their control and efficient. utilisation.
  • the apparatus according to theinventionconp prises essentially a hermetically closed jar in which the aerosols are developed: or into which they are conveyed and from which they can pass out through a tube the extremity of which opens out on the exterior of the jar and is connected to a mask or other means of inlri'alation used by the patient, whilst the other end opens into the upper part of a transparent ball or globe, or similar device, permitting the density of the aerosols to be. controlled.
  • the'quality of aerosols stored in. the jar of the apparatus according to the invention is improved by reason of the factvthat, in this j'ar, the aerosols are freed from theirlarger particles, the condensation of which is probably due to the combined action of the effect of the cold walls of the jar and the: drop in velocity of the flow of aerosols.
  • the absence of large particles in the current leaving the jar is very advantageous, because the presence of large drops in the aerosols intended to be inhaled would cause the precipitation of the aerosols in the upper respiratory passages and would thus greatly reduce or even eliminate the useful efiect the treatment is intended to provide.
  • This apparatus comprises a jar I of suitable capacity closed hermetically by a cover 2.
  • the aerosol generator 3 is suspended from the cover and is in the interior of the apparatus, its tubing 8 being connected to a source of compressed air or other gas.
  • This generator may also be arranged externally of the jar and supply aerosols into the latter through a tube.
  • a transparent globe 4 for example of glass, is mounted, for example by means of screws on the cover 2 and communicates with the jar l.
  • One of the ends of a bent tube projects into the upper" part. of the. globe while its. other end: 1 projectsexternally of thewjanto be connected, for example. by means of a. flexible tube, to: a gas mask; 9; (Fig.1). without inspiration valve or' to some other: device used by the patient for the inhalation of the aerosols;
  • the means: for generating: the aerosols. canbe any know-ntype of aerosollgenerator; Preferably it should be of the type which efie'cts. the" pulverization of the liquid bymeans' oia'. compressed air jet or pulverizer; in: which the: compressed air in aspirati-ng' or ins delivering on mixing: with the liquid; projects the same with extreme violence into the surrounding air.
  • a suitable generator is disclosed in French. PatentNo. 905,303 issued April: 9,. 1945 to Leonard; Bon-ameau.
  • the aerosols Before: emerging through the. tube 5, the aerosols must necessarily pass. through the: glass globe: 4i By'me'ans' of? a comparison charter by means. of. ground or frosted glasses, the density of the aerosols can be checked by comparing the opacity of the. globe: containing: the aerosols with that ofv the saidchart or of the said ground or frosted glasses; Naturally; any other means of control. can-be substitutedfor the glass globe, for example a. photometer permitting very precise measurem'entsa.
  • the tube 6 and the expiration valve of the mask are closed, whilst an absorbent cartridge for carbonic acid is inserted in the flexible tube which, as indicated above, connects the end 1 of the U-shaped tube to the gas mask 9, or it is inserted in the intake opening of the gas mask.
  • the patient thus inhales from and exhales into the hermetically sealed jar I which has been previously filled with aerosols. This method of operation is suitable when a small number of inhalations suffices to obtain the effect sought by means of the treatment.
  • the apparatus When a more prolonged treatment is necessary, the apparatus is used with open circuit. In this case, the presence of the tube 6 is necessary.
  • a gas mask 9 (Fig. l) the latter must be provided with an expiration valve l0, and an inspiration valve H may be provided on the mask or in the tube 6 for avoiding the escape of aerosols.
  • the tube 1 In the apparatus shown in Fig. 2, the tube 1 is provided with a mouth-piece [2 instead of being connected 3 to a gas mask.
  • the expiration valve is arranged at the end of the tube 1, while the inhalation valve II is arranged at the lower end of the tube 6.
  • the compressed air (or other gas) necessary for the production of the aerosols may in particular be supplied by a hand pump or electric compressor or simply drawn from a compressed air flask provided with an expansion valve.
  • the device according to the invention may be mounted, if desired with its source of compressed air on a carriage which may also carry the medicaments and the accessories necessary for the treatment.
  • An apparatus for the use of medicinal aerosols comprising a hermetically sealed jar, means for supplying this jar with medicinal aerosols, a device for permitting the density of the aerosols to be controlled and comprising a chamber directly opening into said jar, a delivery tube having one end opening into the upper part of said chamber and having its other end opening externally of the jar, and means for connecting said tube to inhalation means used by the patient.
  • An apparatus for the use of medicinal aerosols comprising a hermetically sealed jar, means arranged in said jar for developing aerosols therein, a device for permitting the density of the aerosols to be controlled and comprising a chamber directly opening into said jar, a delivery tube having one end opening into the upper part of said chamber and having its other end opening externally of the jar, and means for connecting said tube to inhalation means used by the patient.
  • An apparatus for the supply of medicinal aerosols comprising a hermetically sealed jar, means for supplying this jar with medicinal aerosols, a transparent globe mounted on the top of said jar and directly opening into the latter, and a delivery tube extending into said globe and having one end opening into the upper part of the latter, its other end opening externally of the jar, and means for connecting said tube to inhalation means used by the patient.
  • An apparatus for the use of medicinal aerosols comprising a jar, means for supplying this jar with medicinal aerosols, a device for permitting the density of the aerosols to be controlled and including a chamber directly opening into said jar, a pipe dipping into said jar and opening to atmosphere, a delivery tube having one end opening into the upper part of said chamber and having its other end opening externally of the jar, means for connecting said tube to inhalation means used by the patient and comprising an exhalation valve, and an inhalation valve arranged between the outer ends of said tube and. said pipe.
  • An apparatus for the use of medicinal aerosols comprising a jar, means for supplying this jar with medicinal aerosols, a device for permitting the density of the aerosols to be controlled and including a chamber directly opening into said jar, a pipe dipping into said jar and opening to atmosphere, a delivery tube having one end, opening into the upper part of said chamber and having its other end opening externally of the jar, a mouth-piece adapted to said tube for permitting inhalation of aerosols by a patient, an exhalation valve arranged be tween said mouth-piece and the outlet of said tube, and an inhalation valve arranged between said mouth-piece and the inlet of said pipe.

Description

Dec. 16, 1947.v
F. J. M. THEUNISSEN Filed April 11, 1946 1. ///K 1 gm I a m 1 4 5 a I l 5 1 H H H 7.
62 Id A H m v 1 45 a I 7 P 5. H 4
- 0W5 70/9.- FRANCO/sum (VA/P14: mf'a/wwixv AGf/VT Patented Dec. 16, 1947 KBPH-REATUS FGRTHE USE? OF AEROSOLS Francois. Jean Marie. Tlleuni'ssen, Brussels, Belgi'um", as'signor to Societe Anonymc Teco, Bois- Application: April: 11, 19%;. Serial Notv 661,187- In. Belgium October 4-,,194-1- Section' 1 Public Law 690, August 8, 1946 Patent expires October 4, 1961 6 Glaims To permit the proper use of medicinal products in the. form of aerosols intended to be inhaled; it' is advisable t'obe able tocollect these in such mann'e'ras to have available a quantity of aerosols sufiicient fora complete treatment and to" be able to controland estimate theirdensity.
The presentinvention has for its object to pro vide an apparatus permittingthe colle'ctibnv of. aerosols'in quantity appropriate to the object in View, as also their control and efficient. utilisation.
The apparatus according to theinventionconp prises essentially a hermetically closed jar in which the aerosols are developed: or into which they are conveyed and from which they can pass out through a tube the extremity of which opens out on the exterior of the jar and is connected to a mask or other means of inlri'alation used by the patient, whilst the other end opens into the upper part of a transparent ball or globe, or similar device, permitting the density of the aerosols to be. controlled.
Furthermore, it hasbeen found that the'quality of aerosols stored in. the jar of the apparatus according to the invention is improved by reason of the factvthat, in this j'ar, the aerosols are freed from theirlarger particles, the condensation of which is probably due to the combined action of the effect of the cold walls of the jar and the: drop in velocity of the flow of aerosols. The absence of large particles in the current leaving the jar is very advantageous, because the presence of large drops in the aerosols intended to be inhaled would cause the precipitation of the aerosols in the upper respiratory passages and would thus greatly reduce or even eliminate the useful efiect the treatment is intended to provide.
The invention will now be described in greater detail with reference to the accompanying drawings which by way of example show sectional views of two embodiments of the apparatus according to the invention.
This apparatus comprises a jar I of suitable capacity closed hermetically by a cover 2. In the example illustrated, the aerosol generator 3 is suspended from the cover and is in the interior of the apparatus, its tubing 8 being connected to a source of compressed air or other gas. This generator may also be arranged externally of the jar and supply aerosols into the latter through a tube.
A transparent globe 4, for example of glass, is mounted, for example by means of screws on the cover 2 and communicates with the jar l. One of the ends of a bent tube projects into the upper" part. of the. globe while its. other end: 1 projectsexternally of thewjanto be connected, for example. by means of a. flexible tube, to: a gas mask; 9; (Fig.1). without inspiration valve or' to some other: device used by the patient for the inhalation of the aerosols;
The means: for generating: the aerosols. canbe any know-ntype of aerosollgenerator; Preferably it should be of the type which efie'cts. the" pulverization of the liquid bymeans' oia'. compressed air jet or pulverizer; in: which the: compressed air in aspirati-ng' or ins delivering on mixing: with the liquid; projects the same with extreme violence into the surrounding air. A suitable generator is disclosed in French. PatentNo. 905,303 issued April: 9,. 1945 to Leonard; Bon-ameau.
Before: emerging through the. tube 5, the aerosols must necessarily pass. through the: glass globe: 4i By'me'ans' of? a comparison charter by means. of. ground or frosted glasses, the density of the aerosols can be checked by comparing the opacity of the. globe: containing: the aerosols with that ofv the saidchart or of the said ground or frosted glasses; Naturally; any other means of control. can-be substitutedfor the glass globe, for example a. photometer permitting very precise measurem'entsa.
The cover 2 also carries a tube 6 which p=rojects into the jar I, which permits communication with the atmosphere and which may be closed or provided with an inspiration valve depending on the use made of the apparatus which may be used either in closed circuit or in open circuit.
In the first case, the tube 6 and the expiration valve of the mask are closed, whilst an absorbent cartridge for carbonic acid is inserted in the flexible tube which, as indicated above, connects the end 1 of the U-shaped tube to the gas mask 9, or it is inserted in the intake opening of the gas mask. The patient thus inhales from and exhales into the hermetically sealed jar I which has been previously filled with aerosols. This method of operation is suitable when a small number of inhalations suffices to obtain the effect sought by means of the treatment.
When a more prolonged treatment is necessary, the apparatus is used with open circuit. In this case, the presence of the tube 6 is necessary. When the tube 1 is connected to a gas mask 9 (Fig. l) the latter must be provided with an expiration valve l0, and an inspiration valve H may be provided on the mask or in the tube 6 for avoiding the escape of aerosols. In the apparatus shown in Fig. 2, the tube 1 is provided with a mouth-piece [2 instead of being connected 3 to a gas mask. The expiration valve is arranged at the end of the tube 1, while the inhalation valve II is arranged at the lower end of the tube 6. When the jar l is filled with aerosols to the required density, the inhalations commence, the generator 3 continuing to function.
The compressed air (or other gas) necessary for the production of the aerosols may in particular be supplied by a hand pump or electric compressor or simply drawn from a compressed air flask provided with an expansion valve.
It will be understood that the device according to the invention may be mounted, if desired with its source of compressed air on a carriage which may also carry the medicaments and the accessories necessary for the treatment.
What I claim is:
1. An apparatus for the use of medicinal aerosols, comprising a hermetically sealed jar, means for supplying this jar with medicinal aerosols, a device for permitting the density of the aerosols to be controlled and comprising a chamber directly opening into said jar, a delivery tube having one end opening into the upper part of said chamber and having its other end opening externally of the jar, and means for connecting said tube to inhalation means used by the patient.
2. An apparatus for the use of medicinal aerosols, comprising a hermetically sealed jar, means arranged in said jar for developing aerosols therein, a device for permitting the density of the aerosols to be controlled and comprising a chamber directly opening into said jar, a delivery tube having one end opening into the upper part of said chamber and having its other end opening externally of the jar, and means for connecting said tube to inhalation means used by the patient.
3. An apparatus for the supply of medicinal aerosols, comprising a hermetically sealed jar, means for supplying this jar with medicinal aerosols, a transparent globe mounted on the top of said jar and directly opening into the latter, and a delivery tube extending into said globe and having one end opening into the upper part of the latter, its other end opening externally of the jar, and means for connecting said tube to inhalation means used by the patient.
4. An apparatus according to claim 3, in which the transparent globe is fixed in a detachable manner to the top of said jar.
5. An apparatus for the use of medicinal aerosols, comprising a jar, means for supplying this jar with medicinal aerosols, a device for permitting the density of the aerosols to be controlled and including a chamber directly opening into said jar, a pipe dipping into said jar and opening to atmosphere, a delivery tube having one end opening into the upper part of said chamber and having its other end opening externally of the jar, means for connecting said tube to inhalation means used by the patient and comprising an exhalation valve, and an inhalation valve arranged between the outer ends of said tube and. said pipe.
6. An apparatus for the use of medicinal aerosols, comprising a jar, means for supplying this jar with medicinal aerosols, a device for permitting the density of the aerosols to be controlled and including a chamber directly opening into said jar, a pipe dipping into said jar and opening to atmosphere, a delivery tube having one end, opening into the upper part of said chamber and having its other end opening externally of the jar, a mouth-piece adapted to said tube for permitting inhalation of aerosols by a patient, an exhalation valve arranged be tween said mouth-piece and the outlet of said tube, and an inhalation valve arranged between said mouth-piece and the inlet of said pipe.
FRANCOIS JEAN MARIE 'IHEUNISSEN.
REFERENCES CITED The following references are of record in the file of this patent:
UNITED STATES PATENTS Number Name Date 1,202,877 Margan Oct. 31, 1916 2,230,342 Zabban Feb. 4, 1941 FOREIGN PATENTS Number Country Date 92,276 Austria Apr. 25, 1923
US661187A 1941-10-04 1946-04-11 Apparatus for the use of medicinal aerosols Expired - Lifetime US2432946A (en)

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NL (1) NL65665C (en)

Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2845928A (en) * 1953-01-28 1958-08-05 Misto2 Gen Equipment Co Bronchopulmonary therapeutic apparatus
US2869188A (en) * 1950-06-06 1959-01-20 Misto2 Gen Equipment Co Medicinal inhalant atomization
US3350318A (en) * 1964-02-18 1967-10-31 Fmc Corp Method of producing detergent composition
US3744771A (en) * 1970-07-20 1973-07-10 Ahldea Corp Disposable liquid entraining system
US4173977A (en) * 1977-03-25 1979-11-13 Cavitron Corporation Aerosol interface
US4318397A (en) * 1979-12-31 1982-03-09 Matsushita Seiko Co., Ltd. Atomizing apparatus
WO1991012040A1 (en) * 1990-02-16 1991-08-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Powder inhalator
US5645049A (en) * 1992-11-09 1997-07-08 Trudell Medical Limited Exhalation valve for face mask with spacer chamber connection
US5813401A (en) * 1996-10-15 1998-09-29 Radcliff; Janet H. Nebulizer automatic control valve
US20030214797A1 (en) * 2002-05-15 2003-11-20 International Business Machines Corporation Multilayer printed circuit board
US20040014917A1 (en) * 2000-10-24 2004-01-22 Thomas Eberle Catalyst support, production and use thereof in the polymerization of olefins
US7004162B1 (en) 1992-11-09 2006-02-28 Canadian Monaghan, Ltd. Exhalation valve
US7013896B2 (en) 2001-05-08 2006-03-21 Trudell Medical International Mask with inhalation valve
US7448653B2 (en) 2005-06-10 2008-11-11 Value Plastics, Inc. Female connector for releasable coupling with a male connector defining a fluid conduit
US7806139B2 (en) 2006-01-20 2010-10-05 Value Plastics, Inc. Fluid conduit coupling assembly having male and female couplers with integral valves
USD629894S1 (en) 2008-07-03 2010-12-28 Value Plastics, Inc. Male body of connector for fluid tubing
USD630320S1 (en) 2008-07-03 2011-01-04 Value Plastics, Inc. Connector for fluid tubing
US7878553B2 (en) 2003-09-12 2011-02-01 Value Plastics, Inc. Releasable connection assembly for joining tubing sections
USD634840S1 (en) 2008-07-03 2011-03-22 Value Plastics, Inc. Female body of connector for fluid tubing
USD645547S1 (en) 2007-11-19 2011-09-20 Value Plastics, Inc. Male quick connect fitting
USD649240S1 (en) 2009-12-09 2011-11-22 Value Plastics, Inc. Male dual lumen bayonet connector
USD650478S1 (en) 2009-12-23 2011-12-13 Value Plastics, Inc. Female dual lumen connector
USD652510S1 (en) 2011-02-11 2012-01-17 Value Plastics, Inc. Connector for fluid tubing
USD652511S1 (en) 2011-02-11 2012-01-17 Value Plastics, Inc. Female body of connector for fluid tubing
USD655393S1 (en) 2009-06-23 2012-03-06 Value Plastics, Inc. Multi-port valve
USD663022S1 (en) 2011-02-11 2012-07-03 Nordson Corporation Male body of connector for fluid tubing
US8235426B2 (en) 2008-07-03 2012-08-07 Nordson Corporation Latch assembly for joining two conduits
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USD699841S1 (en) 2011-07-29 2014-02-18 Nordson Corporation Female body of connector for fluid tubing
USD699840S1 (en) 2011-07-29 2014-02-18 Nordson Corporation Male body of connector for fluid tubing
USD709612S1 (en) 2011-12-23 2014-07-22 Nordson Corporation Female dual lumen connector
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US9388929B2 (en) 2009-12-09 2016-07-12 Nordson Corporation Male bayonet connector
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US9464741B2 (en) 2009-12-09 2016-10-11 Nordson Corporation Button latch with integrally molded cantilever springs
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1202877A (en) * 1915-12-18 1916-10-31 Willard F Clark Anesthesia apparatus.
AT92276B (en) * 1921-01-11 1923-04-25 Franz Tremml Suction inhaler.
US2230342A (en) * 1937-10-29 1941-02-04 Zabban Benvenuto Device for the production of artificial fogs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1202877A (en) * 1915-12-18 1916-10-31 Willard F Clark Anesthesia apparatus.
AT92276B (en) * 1921-01-11 1923-04-25 Franz Tremml Suction inhaler.
US2230342A (en) * 1937-10-29 1941-02-04 Zabban Benvenuto Device for the production of artificial fogs

Cited By (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2869188A (en) * 1950-06-06 1959-01-20 Misto2 Gen Equipment Co Medicinal inhalant atomization
US2845928A (en) * 1953-01-28 1958-08-05 Misto2 Gen Equipment Co Bronchopulmonary therapeutic apparatus
US3350318A (en) * 1964-02-18 1967-10-31 Fmc Corp Method of producing detergent composition
US3744771A (en) * 1970-07-20 1973-07-10 Ahldea Corp Disposable liquid entraining system
US4173977A (en) * 1977-03-25 1979-11-13 Cavitron Corporation Aerosol interface
US4318397A (en) * 1979-12-31 1982-03-09 Matsushita Seiko Co., Ltd. Atomizing apparatus
WO1991012040A1 (en) * 1990-02-16 1991-08-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Powder inhalator
US5320714A (en) * 1990-02-16 1994-06-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Powder inhalator
US5988160A (en) * 1992-11-09 1999-11-23 Trudell Medical Limited Exhalation valve for face mask with spacer chamber connection
US5645049A (en) * 1992-11-09 1997-07-08 Trudell Medical Limited Exhalation valve for face mask with spacer chamber connection
US7004162B1 (en) 1992-11-09 2006-02-28 Canadian Monaghan, Ltd. Exhalation valve
US5813401A (en) * 1996-10-15 1998-09-29 Radcliff; Janet H. Nebulizer automatic control valve
US20040014917A1 (en) * 2000-10-24 2004-01-22 Thomas Eberle Catalyst support, production and use thereof in the polymerization of olefins
US7013896B2 (en) 2001-05-08 2006-03-21 Trudell Medical International Mask with inhalation valve
US7084355B2 (en) 2002-05-15 2006-08-01 International Business Machines Corporation Multilayer printed circuit board
US20030214797A1 (en) * 2002-05-15 2003-11-20 International Business Machines Corporation Multilayer printed circuit board
US7878553B2 (en) 2003-09-12 2011-02-01 Value Plastics, Inc. Releasable connection assembly for joining tubing sections
US7448653B2 (en) 2005-06-10 2008-11-11 Value Plastics, Inc. Female connector for releasable coupling with a male connector defining a fluid conduit
US7770939B2 (en) 2005-06-10 2010-08-10 Value Plastics, Inc. Female connector for releasable coupling with a male connector defining a fluid conduit
US8113546B2 (en) 2005-06-10 2012-02-14 Value Plastics, Inc. Latching female fluid tubing coupler
US7806139B2 (en) 2006-01-20 2010-10-05 Value Plastics, Inc. Fluid conduit coupling assembly having male and female couplers with integral valves
US8397756B2 (en) 2006-01-20 2013-03-19 Nordson Corporation Fluid conduit couplers with depressible latch mechanism
USD654573S1 (en) 2007-11-19 2012-02-21 Value Plastics, Inc. Female quick connect fitting
USD645547S1 (en) 2007-11-19 2011-09-20 Value Plastics, Inc. Male quick connect fitting
US8596688B2 (en) 2008-07-03 2013-12-03 Nordson Corporation Latch assembly for joining two conduits
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Also Published As

Publication number Publication date
FR958937A (en) 1950-03-20
CH252451A (en) 1947-12-31
NL65665C (en)
BE442962A (en)
GB603455A (en) 1948-06-16

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