US2430740A - Therapeutic dressing - Google Patents

Therapeutic dressing Download PDF

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Publication number
US2430740A
US2430740A US456698A US45669842A US2430740A US 2430740 A US2430740 A US 2430740A US 456698 A US456698 A US 456698A US 45669842 A US45669842 A US 45669842A US 2430740 A US2430740 A US 2430740A
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Prior art keywords
fibers
boric acid
cotton
therapeutic
melted
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US456698A
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Arthur E Sharples
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A61L2300/104—Silver, e.g. silver sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Definitions

  • This invention relates to therapeutic dressings which may be conveniently and efiiciently applied to the affected part.
  • This application is a continuation in part of my prior application Serial Number 348,553, filed July 30, 1940.
  • Mineral medicaments are especially dificult of application and usually may be practically used only when reduced to a powder. Such form, however, is usually wasteful in application, variable in concentration and shiftable in position and otherwise does not lend itself readily to the formation of convenient and efiicient dressings.
  • the mineral medicament is reduced to a fibrous form similar to absorbent cotton.
  • the medicament is molten at which time there may be introduced into it other desirable ingredients which are then contained in the fibrous or filamentary product.
  • a fibrous mineral medicament may be mixed with fibers which are inert therapeutically.
  • fibers which are inert therapeutically.
  • Such latter fibers may be vegetable, such as cotton or an animal fiber, such as wool.
  • boric acid which is a commonly used medicament may be made into the form of fibers by melting it and thereafter forming fibers from the molten material in the same manner that fibers are formed from glass, in any suitable manner, for instance in the manner described in the U. S. Patent No. 2,156,316, issued to Games Slayter and John H. Thomas, which discloses the socalled melted and blown method of forming fibers, or in the manner illustrated in U. S. Patent No. 2,165,318, issued to John H. Thomas and Ed Fletcher, which discloses a so-called spinerette method, or in the manner illustrated in U. S. Patent No. 2,287,557, issued to Dr. Piero Modigliani which discloses a continuous drawn fiber method, or in the U. S. Patent No. 2,156,982, issued to Charles J. I-Iarford and Earl Stafford, which discloses the so-called spin throw method.
  • the melting operation causes the boric acid to become boric oxide so that the fibers as formed from the molten boric acid are fibers of boric oxide.
  • the addition of water to boric oxide produces boric acid, the oxide being very unstable, so that when the fibers of boric oxide are applied to the affected part the moisture of the body or other added moisture will cause the formation of boric acid.
  • the fibers produced from boric acid may, if desired, be mixed with a therapeutically inert fiber, such as absorbent cotton.
  • a proportion of the mixed fibers which is of general usefulness is ninety percent of cotton fiber and ten percent (10%) of the boric acid fiber.
  • antiseptic materials or other therapeutically active materials as for instance silver oxide or zinc oxide.
  • rials may be introduced into the molten boric acid just prior to its reduction to the fibrous form so that the resulting fibrous material will acoordingly contain such antiseptics and will act upon the aifected parts to which it is applied.
  • This treatment causes the metallic oxide to lose its oxygen so that the metallic silve or Zinc is present in the produced fibers as a colloidal dispersion, that is an extremely fine state of division which enhances its beneficial effect upon the affected parts.
  • Sodium chloride which is known to have beneficial therapeutic effects, may be embodied in the fibers formed from boric acid by adding sodium chloride in desired amounts to the molten boric acid prior to forming it into fibers.
  • Fibers thus formed may be thoroughly intermixed with therapeutically inert fibrous material where it is desired to do so and this mixture of therapeutically active and therapeutically inert fibers may be used as a therapeutic dressing.
  • the medicated fibers either by themselves or admixed with therapeutically inert material may be applied to the affected parts in the same manner as absorbent cotton or surgical gauze would be applied.
  • a therapeutic dressing comprising in combination therapeutically active filamentary fibers having the form of cotton and composed of melted and blown boric acid and therapeutically inert fibers thoroughly mixed therewith.
  • a therapeutic dressing comprising filamentary fibers having the form of cotton and composed of melted and blown boric acid in combination with fibers of cotton.
  • a therapeutic dressing comprising filamentary fibers havi g the form of cotton and formed from melted and blown boric acid and another therapeutically active material, said boric acid and other therapeutical material being mixed and melted together before being blown.
  • a therapeutic dressing comprising filamentary fibers having the form of cotton and formed from melted and blown boric acid and a silver salt, said boric acid and silver salt being mixed and melted together before being blown.
  • a therapeutic dressing comprising in combination filamentary fibers having the form of 4 cotton and. formed from a mixture of melted and blown boric acid and at least one other therapeutic active material, and fibers of therapeutically inert material.
  • a therapeutic dressing comprising in combination filamentary fibers having the form of cotton and formed from a mixture of melted and blown boric acid and at least one other therapeutic active material, and therapeutically inert cotton fibers.
  • a therapeutic dressing comprising in combination therapeutically active filamentary fibers having the form of cotton and made from boric acid and therapeutically inert fibers thoroughly mixed therewith.
  • a therapeutic dressing comprising in combination therapeutically active filamentary fibers having the form of cotton and composed of 4 melted and spun boric acid and therapeutically inert fibers thoroughly mixed therewith.
  • a therapeutic dressing comprising in combination therapeutically active filamentary fibers having the form of cotton and. composed of melted and drawn boric acid and therapeutically inert fibers thoroughly mixed therewith.

Description

Patented Nov. 11, 1947 UNITED STA ENT OFFICE No Drawing. Application August 29,. 1942, Serial No. 456,698
9 Claims. 1
This invention relates to therapeutic dressings which may be conveniently and efiiciently applied to the affected part. This application is a continuation in part of my prior application Serial Number 348,553, filed July 30, 1940.
Mineral medicaments are especially dificult of application and usually may be practically used only when reduced to a powder. Such form, however, is usually wasteful in application, variable in concentration and shiftable in position and otherwise does not lend itself readily to the formation of convenient and efiicient dressings.
According to the present invention, the mineral medicament is reduced to a fibrous form similar to absorbent cotton. In the process of producing fibers the medicament is molten at which time there may be introduced into it other desirable ingredients which are then contained in the fibrous or filamentary product.
In order to spread the medicament over a larger area and provide a carrier for it, a fibrous mineral medicament may be mixed with fibers which are inert therapeutically. Such latter fibers may be vegetable, such as cotton or an animal fiber, such as wool.
Thus, boric acid which is a commonly used medicament may be made into the form of fibers by melting it and thereafter forming fibers from the molten material in the same manner that fibers are formed from glass, in any suitable manner, for instance in the manner described in the U. S. Patent No. 2,156,316, issued to Games Slayter and John H. Thomas, which discloses the socalled melted and blown method of forming fibers, or in the manner illustrated in U. S. Patent No. 2,165,318, issued to John H. Thomas and Ed Fletcher, which discloses a so-called spinerette method, or in the manner illustrated in U. S. Patent No. 2,287,557, issued to Dr. Piero Modigliani which discloses a continuous drawn fiber method, or in the U. S. Patent No. 2,156,982, issued to Charles J. I-Iarford and Earl Stafford, which discloses the so-called spin throw method.
The melting operation causes the boric acid to become boric oxide so that the fibers as formed from the molten boric acid are fibers of boric oxide. The addition of water to boric oxide, however, produces boric acid, the oxide being very unstable, so that when the fibers of boric oxide are applied to the affected part the moisture of the body or other added moisture will cause the formation of boric acid.
The fibers produced from boric acid may, if desired, be mixed with a therapeutically inert fiber, such as absorbent cotton. A proportion of the mixed fibers which is of general usefulness is ninety percent of cotton fiber and ten percent (10%) of the boric acid fiber.
It may be desirable to have contained in the therapeutic fibrous material antiseptic materials or other therapeutically active materials as for instance silver oxide or zinc oxide. rials may be introduced into the molten boric acid just prior to its reduction to the fibrous form so that the resulting fibrous material will acoordingly contain such antiseptics and will act upon the aifected parts to which it is applied. This treatment causes the metallic oxide to lose its oxygen so that the metallic silve or Zinc is present in the produced fibers as a colloidal dispersion, that is an extremely fine state of division which enhances its beneficial effect upon the affected parts.
Sodium chloride, which is known to have beneficial therapeutic effects, may be embodied in the fibers formed from boric acid by adding sodium chloride in desired amounts to the molten boric acid prior to forming it into fibers.
Fibers thus formed may be thoroughly intermixed with therapeutically inert fibrous material where it is desired to do so and this mixture of therapeutically active and therapeutically inert fibers may be used as a therapeutic dressing. The medicated fibers either by themselves or admixed with therapeutically inert material may be applied to the affected parts in the same manner as absorbent cotton or surgical gauze would be applied.
While the invention has been illustrated in what are considered its best applications, it may have other embodiments without departing from its spirit and is not therefore limited to the precise materials or proportions nor to the precise details of the method of formation as recited.
I claim:
1. A therapeutic dressing comprising in combination therapeutically active filamentary fibers having the form of cotton and composed of melted and blown boric acid and therapeutically inert fibers thoroughly mixed therewith.
2. A therapeutic dressing comprising filamentary fibers having the form of cotton and composed of melted and blown boric acid in combination with fibers of cotton.
3. A therapeutic dressing comprising filamentary fibers havi g the form of cotton and formed from melted and blown boric acid and another therapeutically active material, said boric acid and other therapeutical material being mixed and melted together before being blown.
Such mate- 4. A therapeutic dressing comprising filamentary fibers having the form of cotton and formed from melted and blown boric acid and a silver salt, said boric acid and silver salt being mixed and melted together before being blown.
5. A therapeutic dressing comprising in combination filamentary fibers having the form of 4 cotton and. formed from a mixture of melted and blown boric acid and at least one other therapeutic active material, and fibers of therapeutically inert material.
6. A therapeutic dressing comprising in combination filamentary fibers having the form of cotton and formed from a mixture of melted and blown boric acid and at least one other therapeutic active material, and therapeutically inert cotton fibers.
7. A therapeutic dressing comprising in combination therapeutically active filamentary fibers having the form of cotton and made from boric acid and therapeutically inert fibers thoroughly mixed therewith.
8. A therapeutic dressing comprising in combination therapeutically active filamentary fibers having the form of cotton and composed of 4 melted and spun boric acid and therapeutically inert fibers thoroughly mixed therewith.
9. A therapeutic dressing comprising in combination therapeutically active filamentary fibers having the form of cotton and. composed of melted and drawn boric acid and therapeutically inert fibers thoroughly mixed therewith.
ARTHUR E. SHARPLES.
REFERENCES CITED The following references are of record in the file of this patent:
UNITED STATES PATENTS Number Name Date 401,547 Francken et al Apr. 16, 1889 FOREIGN PATENTS Number Country Date 460,330 Great Britain Jan. 26, 1937 2,635 Great Britain 187"] OTHER REFERENCES Pharmaceutical Recipe Book (1929), page 19. (Copy in Sci. Libr.)
US456698A 1942-08-29 1942-08-29 Therapeutic dressing Expired - Lifetime US2430740A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3122479A (en) * 1957-11-14 1964-02-25 David F Smith Hemostatic surgical dressings
US4191740A (en) * 1976-11-11 1980-03-04 Merck Patent Gesellschaft Mit Beschrankter Haftung Synthetic resin-base, antibiotic compositions containing amino acids
US4191743A (en) * 1976-11-02 1980-03-04 Merck Patent Gesellschaft Mit Beschrankter Haftung Antibacterial wound dressing
US4608044A (en) * 1978-04-03 1986-08-26 Molnlycke Ab Compress for treatment of wounds
US5972366A (en) * 1994-11-28 1999-10-26 The Unites States Of America As Represented By The Secretary Of The Army Drug releasing surgical implant or dressing material
US20090117059A1 (en) * 2007-08-03 2009-05-07 Oronsky Bryan T Compositions and methods of use thereof, for the treatment of oral pain, comprising cloves or extracts thereof in combination with a steroid
US20120220911A1 (en) * 2010-01-06 2012-08-30 The Curators Of The University Of Missouri Wound care

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US401547A (en) * 1889-04-16 Victoe francken and joseph pirxay
GB460330A (en) * 1935-10-09 1937-01-26 Arthur Joseph Somer Production of anhydrous boric acid

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US401547A (en) * 1889-04-16 Victoe francken and joseph pirxay
GB460330A (en) * 1935-10-09 1937-01-26 Arthur Joseph Somer Production of anhydrous boric acid

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3122479A (en) * 1957-11-14 1964-02-25 David F Smith Hemostatic surgical dressings
US4191743A (en) * 1976-11-02 1980-03-04 Merck Patent Gesellschaft Mit Beschrankter Haftung Antibacterial wound dressing
US4191740A (en) * 1976-11-11 1980-03-04 Merck Patent Gesellschaft Mit Beschrankter Haftung Synthetic resin-base, antibiotic compositions containing amino acids
US4233287A (en) * 1976-11-11 1980-11-11 Merck Patent Gesellschaft Mit Beschrankter Haftung Synthetic resin-base, antibiotic compositions containing amino acids
US4608044A (en) * 1978-04-03 1986-08-26 Molnlycke Ab Compress for treatment of wounds
US5972366A (en) * 1994-11-28 1999-10-26 The Unites States Of America As Represented By The Secretary Of The Army Drug releasing surgical implant or dressing material
US20090117059A1 (en) * 2007-08-03 2009-05-07 Oronsky Bryan T Compositions and methods of use thereof, for the treatment of oral pain, comprising cloves or extracts thereof in combination with a steroid
US20120220911A1 (en) * 2010-01-06 2012-08-30 The Curators Of The University Of Missouri Wound care
US8535710B2 (en) * 2010-01-06 2013-09-17 The Curators Of The University Of Missouri Wound care
US9486554B2 (en) 2010-01-06 2016-11-08 The Curators Of The University Of Missouri Wound care compositions comprising borate (B2O3) glass-based particles
US10624982B2 (en) 2010-01-06 2020-04-21 The Curators Of The University Of Missouri Wound care compositions

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