US2395800A - Method for the preparation of 1,3-diketones - Google Patents
Method for the preparation of 1,3-diketones Download PDFInfo
- Publication number
- US2395800A US2395800A US537532A US53753244A US2395800A US 2395800 A US2395800 A US 2395800A US 537532 A US537532 A US 537532A US 53753244 A US53753244 A US 53753244A US 2395800 A US2395800 A US 2395800A
- Authority
- US
- United States
- Prior art keywords
- ester
- acyl
- diketone
- carbon atom
- enol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/12—Ketones containing more than one keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/12—Ketones containing more than one keto group
- C07C49/14—Acetylacetone, i.e. 2,4-pentanedione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/385—Saturated compounds containing a keto group being part of a ring
- C07C49/403—Saturated compounds containing a keto group being part of a ring of a six-membered ring
Definitions
- enic carbon atom to form a diketone in which .two carbonyl groups are attached to the same carbon atom.
- Diketones of the type having car'- bonyl groups attached to the same carbon atom are commonly referred to as 1,3-diketones or beta-diketones.
- Enolesters which may be isomerized to the corresponding 1,3-diketone include the acetic acid esters of the enol form of such ketones as: acetone, CHaCOCHa; methyl ethyl ketone,
- CHaCOCzHs methyl propyl ketones, CHaCOCsH-z; methyl butyl ketones, CH3COC4H9; methyl pentyl ketones, CHaCOCsHn; methyl hexyl ketones, CI-IzCOCaHra; methyl heptyl ketones, CH3COC7H15; methyl octyl ketones, CHaCOCaI-In; methyl nonyl ketones, CH3COC9H19; methyl decyl ketones,
- CaHioO methyl cyclohexanones, CHaCsHaO; ethyl cyclohexanones, CiI-IaCaHsO; propyl cyclohexanones.
- CaH'zCeHaO' butyl cyclohexanones,
- CHIiC6H4COOH CaHsCHzCOOH, phenyl propionic acids, C6H5C2H4COOH, phenyl butyric acids, CaHaCaI-IsCOOH, dimethyl benzoic acids,
- R and R may be hydrogen, aliphatic or aromatic; R and R. may be aliphatic or aromatic or R and R taken together may be part of a cycloaliphatic ring.
- aliphatic it is meant to include cycloaliphatic.
- The. conversion of an enol-ester to the isomeric beta-diketone may be carried out by heating the starting material to an elevated temperature in a suitable reactor. If desired, the enol-ester may be refluxed in a ketene lamp over a heated metal filament.
- the beta-diketones the conversion may beefiected by passing the vapors of the enol-ester through a heated tube which is fitted with a vaporizer, preheater and condenser.
- the tube may be constructed of chrome iron, nichrome, stainless steel,
- yields of diketone of from 20 to per cent may be obtained in efiiciencies as high as stantially above 500 jimately 500 obtained from the three-hour run, there was ob- 101 grams of benzoyl acetone,
- the converter may ,be packed with an inert material although ex reaction products of significance are formed, and
- the main reaction product may be separated from unchanged starting material by ordinary proce-' dures for recovery or purification, as by distillation at a suitable pressure or 'the like.
- the usefulconversion temperatures lie in the range from 300 to 700 C.,' but the most satisfactory'results are obtainableat a temperature of about 500 to 600 C. which is preferred. with decrease in -temperatures below 500 C., the yield falls off rapidly while at temperatures sub- C., the loss of the acylated ketone by decomposition becomes excessive.
- Errol-esters which are the starting materials for carrying out my process may be obtained in various ways, for instance, by ester interchange, using an enol-ester such as isopropenyl acetate as the acylating agent for reaction with the ketone. This latter method is no part of the present invention but is described and claimed in copending applications of Quattlebaum and No'ifsinger flied on or about 539,024 and 539.025.
- Example 1 CHaC'OCI-IaCOCHs Acetyl acetone Isopropenyl acetate -Wa's passed through a heated chrome iron tube, having an inside diameter of one inch, at a uniform rate of about 225 grams per hour for a period of four hours.
- the apparatus included a vaporizer and a preheater for the isopropenyl acetate and an efilcient condenser for collecting the conversion products-at the outlet of the tube. Over a distance of 21 inches of its length the converter tube was maintained at a temperature 01' 500 heating.
- the vaporizer and preheater were maintained at temperatures of 180 C. and 300 C respectively.
- Example 3 millimeters of mercury. 2-ethyi hexanoyl acetone was found to be a colorless liquid having the following properties: D 20/20, 0.9060; N 1.4600.
- the single pass yield was 61.6 per-cent.
- the re-' covery of unchanged starting material was 32.1 grams per cent for an efllciency of 78.3 per cent.
- the amount of unchangcd enol-ester recovered was 180.3 grams.
- the single pass yield was 22.2 per cent and the efliciency 60.5 per cent.
- a method of making a beta-diketone from an enol-ester isomeric therewith which comprises heating an acyl ester oi. the enolic form of a ketone to a temperature of about 300 to 700 to cause said acyl group oi! the acyl ester to migrate to form a diketone having two carbonyl groups attached to the same aliphatic carbon atom.
- a method of making a beta-diketone from an enol-ester isomeric therewith which comprises heating an acyl ester of the enolic form of a ketone to a temperature of about 500 C. to cause said acyl group of the acyl ester to migrate to form a diketone having two carbonyl groups attached to the same aliphatic carbon atom.
- a method of making a beta-diketone from an enol-ester isomeric therewith which comprises heating the acyl ester of a ketone to a temperature of about 300 to 700 C. in the vapor phase to cause said acyl group of the acyl ester to migrate to form a. diketone having two carbonyl groups attached to the same aliphatic carbon atom.
- a method of making a beta-diketone from an enol-ester isomeric therewith which comprises heating an acyl ester of the enolic form of a ketone to a temperature of about 300 to 700 C. to form a diketone having two carbonyl groups attached to the same aliphatic carbon atom, said acyl group containing not more than twelve carbon atoms.
- a method of making a beta-diketone from an enol-ester isomeric therewith which comprises heating an acyl ester of the enolic form of a ketone which ketone contains not more than twelve carbon atoms to a temperature of 300 to 700 C. to cause the acyl group to migrate to form a diketone having the two carbonyl groups attached to the same aliphatic carbon atom.
- a method of making a beta-diketone containing two acyl groups attached to the same methylene carbon atom, CH2- which comprises heating an acyl ester of the enol form of a ketone having a methyl group CH3, attached to the carbonyl group thereof to a temperature of about 300 to 700 C. to cause said ester, to rearrange to form a diketone having two acyl groups attached to the same carbon atom by migration of the acyl'group of said ester from the enolic oxygen atom to the methyl carbon atom of said ketone.
- a method of making a beta-diketone in which one of the carbonyl groups thereofis in a cycloaliphatic ring which comprises heating an acyl ester of the enol form of a cycloaliphatic ketone to a temperature of about 300 to 700 C. to cause said ester to rearrange to form a diketone having the two carbonyl groups attached to the same carbon atom by migration of the acyl group of said ester fromthe enolic oxygen atom to a carbon atom adjacent the carbonyl group of the ketone.
- a method of making an acyl acetone which comprises heating an acyl ester of the enolic form of acetone to a temperature of about 300 to 700 C. to cause said ester to rearrange to form an acyl acetone isomeric therewith by migration of the acyl group from the enolic oxygen atom to a carbon atom.
- a method of making an acyl acetone which comprises heating an aliphatic acyl ester of the enolic form of acetone to a temperature of about 300 to 700 C. to cause said ester to rearrange to form an aliphatic acyl acetone isomeric therewith by migration of the aliphatic acyl group from the enolic oxygen atom to a carbon atom.
- a method of making an acyl acetophenone which includes he'ating an acyl ester of the enolic form of acetophenone to a temperature of about tone by migration of the acyl radical of said ester from the enol oxygen atom to the methyl group of said ketone.
- a method of making an aliphatic acyl acetophenone which includes heating an aliphatic acyl ester of the enolic form of acetophenone to a temperature of about 300 to 700 C. to cause said ester to rearrange to form an aliphatic acyl acetophenone isomeric therewith by migration of the aliphatic acyl group from the enolic oxygen atom to the beta carbon atom of the side chain of acetophenone.
- a method of making acetyl acetone which comprises heating isopropenyl acetate to a temperature of about 500 to 600 C. to cause it .to rearrange by migration of the acetyl group to a carbon atom.
- a method of making acet l acetone which comprises heating isopropenyl acetate to a temperature of about 300 to 700 C. to cause it to rearrange by migration of the acetyl group to a carbon atom.
- a method of making acetyl acetone which comprises heating isopropenyl acetate in the vapor phase at a temperature of about 500 C. to
Description
Patented Mar. 5, 1946 UNITED STATES PATENT. OFFICE METHOD ron THEJREPARATION or 1,3-mnarouss Albert B. Boese, J r., Pittsburgh, Pa., and Frank G.
Young, Jr., Charleston, W. Va., assignors to Chemicals Corporation, a corporation of New York No Drawing. Application May 26, 1944,
Serial No. 537,532
Carbide and Carbon 17 Claims.
, enic carbon atom to form a diketone in which .two carbonyl groups are attached to the same carbon atom. Diketones of the type having car'- bonyl groups attached to the same carbon atom are commonly referred to as 1,3-diketones or beta-diketones.
My discovery seems to be of general applicability to the acyl 'enol-esters of ketones. Enolesters which may be isomerized to the corresponding 1,3-diketone include the acetic acid esters of the enol form of such ketones as: acetone, CHaCOCHa; methyl ethyl ketone,
CHaCOCzHs methyl propyl ketones, CHaCOCsH-z; methyl butyl ketones, CH3COC4H9; methyl pentyl ketones, CHaCOCsHn; methyl hexyl ketones, CI-IzCOCaHra; methyl heptyl ketones, CH3COC7H15; methyl octyl ketones, CHaCOCaI-In; methyl nonyl ketones, CH3COC9H19; methyl decyl ketones,
CHaCOCmHn CzHaCOCeHu propyl cyclohexyl ketones, C3H1COCaH11; cyclohexyl acetone, CsHuCHzCOCHz; cyclohexanone,
CaHioO; methyl cyclohexanones, CHaCsHaO; ethyl cyclohexanones, CiI-IaCaHsO; propyl cyclohexanones. CaH'zCeHaO'; butyl cyclohexanones,
CcHeCcHeO acetophenone, CeHsCOCI-b; tolyl methyl ketones,
CHaCaH4COCHa; benzyl methyl ketone,
, CBH5CH2COCH3 In addition to the acetic acid ester of the enol form of the ketones there may be used ,the enolesters of such acids as: propionic acid,
' cznscoon butyric acids, Cal-IaCOOH, pentanoic acids,
cl'mdoon hexanoic acids, C5H11COOH; heptanoic acids,
CeHmCOOH, octanoic acids, C-IH1'5COQH, non- I phenyl acetic acid,
anoic acids, C8HI7COOH, decanoic acids,
' CaHmCOOI-I benzoic acid, cemcoon, toluic acids,
CHIiC6H4COOH CaHsCHzCOOH, phenyl propionic acids, C6H5C2H4COOH, phenyl butyric acids, CaHaCaI-IsCOOH, dimethyl benzoic acids,
(CH3) 2C6H3COOH hexahydrobenzoic acid, CcHnCOOI-I, hexahydrotoluic acids, CHaCsI-ImCOOH.
The reaction which takes place may be illustrated by the following general equation:
t in which R and R may be hydrogen, aliphatic or aromatic; R and R. may be aliphatic or aromatic or R and R taken together may be part of a cycloaliphatic ring. By the term aliphatic it is meant to include cycloaliphatic.
The. conversion of an enol-ester to the isomeric beta-diketone may be carried out by heating the starting material to an elevated temperature in a suitable reactor. If desired, the enol-ester may be refluxed in a ketene lamp over a heated metal filament. For commercial production 01 the beta-diketones, the conversion may beefiected by passing the vapors of the enol-ester through a heated tube which is fitted with a vaporizer, preheater and condenser. The tube may be constructed of chrome iron, nichrome, stainless steel,
, silica or other material which is resistant to the corrosive action of the diketone produced. On a single pass of the enol-ester through the con verter, yields of diketone of from 20 to per cent may be obtained in efiiciencies as high as stantially above 500 jimately 500 obtained from the three-hour run, there was ob- 101 grams of benzoyl acetone,
80 to 95 per cent. Ii. desired, the converter may ,be packed with an inert material although ex reaction products of significance are formed, and
the main reaction product may be separated from unchanged starting material by ordinary proce-' dures for recovery or purification, as by distillation at a suitable pressure or 'the like.
In general, the usefulconversion temperatures lie in the range from 300 to 700 C.,' but the most satisfactory'results are obtainableat a temperature of about 500 to 600 C. which is preferred. with decrease in -temperatures below 500 C., the yield falls off rapidly while at temperatures sub- C., the loss of the acylated ketone by decomposition becomes excessive.
Errol-esters which are the starting materials for carrying out my process may be obtained in various ways, for instance, by ester interchange, using an enol-ester such as isopropenyl acetate as the acylating agent for reaction with the ketone. This latter method is no part of the present invention but is described and claimed in copending applications of Quattlebaum and No'ifsinger flied on or about 539,024 and 539.025.
The present invention may be further illustrated by the following examples:
Example 1 CHaC'OCI-IaCOCHs Acetyl acetone Isopropenyl acetate -Wa's passed through a heated chrome iron tube, having an inside diameter of one inch, at a uniform rate of about 225 grams per hour for a period of four hours. The apparatusincluded a vaporizer and a preheater for the isopropenyl acetate and an efilcient condenser for collecting the conversion products-at the outlet of the tube. Over a distance of 21 inches of its length the converter tube was maintained at a temperature 01' 500 heating. The vaporizer and preheater were maintained at temperatures of 180 C. and 300 C respectively.
n distillation of the condensate from the four-hour run there was obtained 407 grams of acetyl acetone distilling at 69-70 lute pressure of 100 millimeters of mercury, and
June 6, 1944, --Serials Nos.
C. by electrical cent. There was also recovered 40 grams of unchanged alpha-acetoxy styrene for a conversion efiiciency of 80.1 per cent. 1
Example 3 millimeters of mercury. 2-ethyi hexanoyl acetonewas found to be a colorless liquid having the following properties: D 20/20, 0.9060; N 1.4600.
The single pass yield was 61.6 per-cent. The re-' covery of unchanged starting material was 32.1 grams per cent for an efllciency of 78.3 per cent.
Example 4 HCOOH:
v C a ortho-acetyl cyclohexanone Acetoxycyclohexene made by the reaction of ketene with cyclohexanone 'was converted to ortho-acetylcyclohexanone at. a temperature of 500 0., using a silica tube packed with ceramically bonded, fused aluminum oxide. Except for the packing, the apparatus and procedure were substantially as described in Example 2. Over a period of five hours 574 grams of acetoxycyclohexene were passed through the converter tube.
The resulting condensate which was distilled under reduced pressure yielded 272 grams of ortho-acetyl cyclohexanone, distilling at 80- 80.5 C. at an absolute pressure of 5 millimeters of mercury, and 248 grams of unchanged'starting material. The single pass yield was 43per cent and the efilciency was as 82 per cent.
The foregoing results were obtained after the packed converter had been inservice for a period of time and a thin coating of carbon had been deposited. on thealuminum oxide packing. It was observed that until the thin deposition of carbon had formed, some decomposition of material to lower boiling substances took place, with a resultant lower yield.
Chat an abso- 427 grams of recovered isopropenyl acetate.
These values correspond'to a single pass yield of- 45.3 per cent-and an efliciency of 86.2 per cent.
- Example 2 CoHsCOCHzCOCI-Is 1 which represented a single pass yieldot 60.8 per silica tube at a uniform rate of. about, 55.3 grams per hour for 7-ethyl nonanedione-2,4
The enol-acetate of 5-ethyl heptanone-2 made by the reaction of ketene with the ketone, was converted to the isomeric diketone at a temperature of 500 C., using an unpacked silica tube as the converter. The tube which had an inside diameter of one inch was heated for 22 inches oi. its length. The enol-ester was supplied to the converter at a uniform rate of milliliters per hour. Otherwise the procedure was substantially as described in Example 2. Distillation of the condensate obtained from a three-hour run during which 290 grams of the enol-ester were passed through the converter, yielded 63.2" grams of 7- ethyl nonanedione-2,4 distilling at 119 C., at an absolute pressure of 15 millimeters of mercury. The diketone was found to have the following properties: D 20/20, 0.924; n 20/D, 1.4508; Ma
calculated at 54.10, observed 54.12. The amount of unchangcd enol-ester recovered was 180.3 grams. The single pass yield was 22.2 per cent and the efliciency 60.5 per cent.
The invention is susceptible of modification within the scope of the appended claims.
What is claimed is:
1. A method of making a beta-diketone from an enol-ester isomeric therewith which comprises heating an acyl ester oi. the enolic form of a ketone to a temperature of about 300 to 700 to cause said acyl group oi! the acyl ester to migrate to form a diketone having two carbonyl groups attached to the same aliphatic carbon atom.
2. A method of making a beta-diketone from an enol-ester isomeric therewith which comprises heating an acyl ester of the enolic form of a ketone to a temperature of about 500 C. to cause said acyl group of the acyl ester to migrate to form a diketone having two carbonyl groups attached to the same aliphatic carbon atom.
3. A method of making a beta-diketone from an enol-ester isomeric therewith which comprises heating the acyl ester of a ketone to a temperature of about 300 to 700 C. in the vapor phase to cause said acyl group of the acyl ester to migrate to form a. diketone having two carbonyl groups attached to the same aliphatic carbon atom.
4. A method of making a beta-diketone from an enol-ester isomeric therewith which comprises heating an acyl ester of the enolic form of a ketone to a temperature of about 300 to 700 C. to form a diketone having two carbonyl groups attached to the same aliphatic carbon atom, said acyl group containing not more than twelve carbon atoms.
5. A method of making a beta-diketone from an enol-ester isomeric therewith which comprises heating an acyl ester of the enolic form of a ketone which ketone contains not more than twelve carbon atoms to a temperature of 300 to 700 C. to cause the acyl group to migrate to form a diketone having the two carbonyl groups attached to the same aliphatic carbon atom.
6. A method of making a beta-diketone containing two acyl groups attached to the same methylene carbon atom, CH2-, which comprises heating an acyl ester of the enol form of a ketone having a methyl group CH3, attached to the carbonyl group thereof to a temperature of about 300 to 700 C. to cause said ester, to rearrange to form a diketone having two acyl groups attached to the same carbon atom by migration of the acyl'group of said ester from the enolic oxygen atom to the methyl carbon atom of said ketone.
7. A method of making a beta-diketone containing two aliphatic acyl groups attached to the same methylene carbon atom, -CH2, which comprises heating an aliphatic acyl ester of the enol form of an aliphatic ketone having a methyl group, CH3--, attached to the carbonyl group thereof to a temperature of about 300 to 700 C. to cause said ester to rearrange to form a dikemethylene carbon atom, CH2-, which comprises heating an aromatic acyl ester of the enol form of a ketone having a methyl group and an aromatic group attached to the carbonyl group thereof to a temperature of about 300 to 700 C. to cause said ester to rearrange to form a diketone having two aromatic acyl groups attached to the same carbon atom by migration of the arcmatic acyl group of said ester from the enolic oxygen atom to the methyl carbon atom of said ketone.
9. A method of making a beta-diketone in which one of the carbonyl groups thereofis in a cycloaliphatic ring, which comprises heating an acyl ester of the enol form of a cycloaliphatic ketone to a temperature of about 300 to 700 C. to cause said ester to rearrange to form a diketone having the two carbonyl groups attached to the same carbon atom by migration of the acyl group of said ester fromthe enolic oxygen atom to a carbon atom adjacent the carbonyl group of the ketone.
'10. A method of making an acyl acetone which comprises heating an acyl ester of the enolic form of acetone to a temperature of about 300 to 700 C. to cause said ester to rearrange to form an acyl acetone isomeric therewith by migration of the acyl group from the enolic oxygen atom to a carbon atom.
11. A method of making an acyl acetone which comprises heating an aliphatic acyl ester of the enolic form of acetone to a temperature of about 300 to 700 C. to cause said ester to rearrange to form an aliphatic acyl acetone isomeric therewith by migration of the aliphatic acyl group from the enolic oxygen atom to a carbon atom.
12. A method of making an acyl acetophenone which includes he'ating an acyl ester of the enolic form of acetophenone to a temperature of about tone by migration of the acyl radical of said ester from the enol oxygen atom to the methyl group of said ketone.
8. A method of making a beta-diketone havin two aromatic acyl groups attached to the same 300 to 700 C. to cause said ester to rearrange to form an acyl acetophenone isomeric therewith by migration of the acyl group to the beta carbon atom of the side chain of acetophenone.
13. A method of making an aliphatic acyl acetophenone which includes heating an aliphatic acyl ester of the enolic form of acetophenone to a temperature of about 300 to 700 C. to cause said ester to rearrange to form an aliphatic acyl acetophenone isomeric therewith by migration of the aliphatic acyl group from the enolic oxygen atom to the beta carbon atom of the side chain of acetophenone.
14. A method of making acetyl acetone which comprises heating isopropenyl acetate to a temperature of about 500 to 600 C. to cause it .to rearrange by migration of the acetyl group to a carbon atom.
15. A method of making acet l acetone which comprises heating isopropenyl acetate to a temperature of about 300 to 700 C. to cause it to rearrange by migration of the acetyl group to a carbon atom.
16. A method of making acetyl acetone which comprises heating isopropenyl acetate in the vapor phase at a temperature of about 500 C. to
cause it to rearrange by migration of the acetyl group to a carbon atom,
17. As a new chemical compound 5-ethyl nonanedione-2,4.
ALBERT B. BOESE, JR. FRANK G. YOUNG, JR.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US537532A US2395800A (en) | 1944-05-26 | 1944-05-26 | Method for the preparation of 1,3-diketones |
GB14342/45A GB615523A (en) | 1944-05-26 | 1945-06-07 | Improvements in method for the preparation of 1:3-diketones |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US537532A US2395800A (en) | 1944-05-26 | 1944-05-26 | Method for the preparation of 1,3-diketones |
Publications (1)
Publication Number | Publication Date |
---|---|
US2395800A true US2395800A (en) | 1946-03-05 |
Family
ID=24143040
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US537532A Expired - Lifetime US2395800A (en) | 1944-05-26 | 1944-05-26 | Method for the preparation of 1,3-diketones |
Country Status (2)
Country | Link |
---|---|
US (1) | US2395800A (en) |
GB (1) | GB615523A (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3329711A (en) * | 1963-12-24 | 1967-07-04 | Hoffmann La Roche | Phenylalanine compounds having alpha and beta quaternary carbon atoms |
US3883595A (en) * | 1970-05-28 | 1975-05-13 | Us Agriculture | Process for the preparation of beta dicarbonyl |
US3919275A (en) * | 1970-05-28 | 1975-11-11 | Us Agriculture | Chelated beta dicarbonyl compounds |
US4167641A (en) * | 1978-09-01 | 1979-09-11 | Welebir Andrew J | Preparation of long-chain carboxylic acids and alcohols |
EP0569760A2 (en) * | 1992-05-11 | 1993-11-18 | BASF Aktiengesellschaft | Process for the preparation of 1-cyclopropylbutan-1,3-dione |
EP1083162A1 (en) * | 1999-08-13 | 2001-03-14 | Wacker-Chemie GmbH | Process for the preparation of 1,3-diketones |
US20070155181A1 (en) * | 2002-09-27 | 2007-07-05 | Tokyo Electron Limited | Method and system for etching high-k dielectric materials |
-
1944
- 1944-05-26 US US537532A patent/US2395800A/en not_active Expired - Lifetime
-
1945
- 1945-06-07 GB GB14342/45A patent/GB615523A/en not_active Expired
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3329711A (en) * | 1963-12-24 | 1967-07-04 | Hoffmann La Roche | Phenylalanine compounds having alpha and beta quaternary carbon atoms |
US3883595A (en) * | 1970-05-28 | 1975-05-13 | Us Agriculture | Process for the preparation of beta dicarbonyl |
US3919275A (en) * | 1970-05-28 | 1975-11-11 | Us Agriculture | Chelated beta dicarbonyl compounds |
US4167641A (en) * | 1978-09-01 | 1979-09-11 | Welebir Andrew J | Preparation of long-chain carboxylic acids and alcohols |
EP0569760A2 (en) * | 1992-05-11 | 1993-11-18 | BASF Aktiengesellschaft | Process for the preparation of 1-cyclopropylbutan-1,3-dione |
EP0569760A3 (en) * | 1992-05-11 | 1995-03-22 | Basf Ag | Process for the preparation of 1-cyclopropylbutan-1,3-dione. |
EP1083162A1 (en) * | 1999-08-13 | 2001-03-14 | Wacker-Chemie GmbH | Process for the preparation of 1,3-diketones |
US6310258B1 (en) | 1999-08-13 | 2001-10-30 | Wacker Chemie Gmbh | Process for preparing 1,3-diketones |
US20070155181A1 (en) * | 2002-09-27 | 2007-07-05 | Tokyo Electron Limited | Method and system for etching high-k dielectric materials |
US7781340B2 (en) * | 2002-09-27 | 2010-08-24 | Tokyo Electron Limited | Method and system for etching high-k dielectric materials |
Also Published As
Publication number | Publication date |
---|---|
GB615523A (en) | 1949-01-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US2395800A (en) | Method for the preparation of 1,3-diketones | |
GB623836A (en) | Manufacture of terephthalic acid | |
US2376704A (en) | Preparation of esters of alpha-beta unsaturated monocarboxylic acids | |
Wagner | Rearrangement of α, β-Dibromoketones | |
Vieregge et al. | Chemistry of acetylenic ethers 84: Addition of aldehydes, ketones, esters and amides to 1‐alkynyl ethers under the influence of Lewis acids; direct formation of α, β‐unsaturated esters | |
US2251983A (en) | Process for making vinyl esters and other esters of unsaturated alcohols | |
US2390368A (en) | Production of para-divinylbenzene | |
Alper et al. | Regeneration of carbonyl compounds from oximnes using iron pentacarbonyl and boron trifluoride | |
US2932665A (en) | Preparation of nu, nu-diethyltoluamides | |
CA1077959A (en) | Pyrolysis of limonene-1,2-dialkanoates to give perillyl alkanoates | |
US2417748A (en) | Preparation of methyl acrylate | |
US2577445A (en) | Preparing methacrolein from the dimer thereof | |
Gwynn et al. | Condensation Products of Ketene with Ketones1 | |
Fieser et al. | A New Diene Synthesis of Anthraquinones | |
US2432499A (en) | Acetylation of beta-ketonic compounds | |
US3032491A (en) | Irradiation of cyclohexadienones | |
US2889367A (en) | dimethyl-g t-isutyl indanes | |
US3122588A (en) | Process for the production of aldehydes | |
Blomquist et al. | Reactions of Some Substituted Divinylacetylenes | |
US3244752A (en) | Process for preparing substantially pure rhodinal | |
US2866823A (en) | Process for the removal of formaldehyde from crude pyruvic aldehyde solution | |
US2467095A (en) | Acylation with enol esters | |
US3439042A (en) | Synthesis of pseudoionones | |
Nikishin et al. | Free-radical addition of cyclopenta none and cyclohexanone to α-olefins and allyl ethers | |
US1702844A (en) | Process for the preparation of monocyclic ketones and their alkyl derivatives having more than nine ring members |