US2395109A - Inhaler - Google Patents

Inhaler Download PDF

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Publication number
US2395109A
US2395109A US469907A US46990742A US2395109A US 2395109 A US2395109 A US 2395109A US 469907 A US469907 A US 469907A US 46990742 A US46990742 A US 46990742A US 2395109 A US2395109 A US 2395109A
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US
United States
Prior art keywords
inhaler
ampule
casing
paper
blotting paper
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US469907A
Inventor
Howard B Fonda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Burroughs Wellcome Co USA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Burroughs Wellcome Co USA filed Critical Burroughs Wellcome Co USA
Priority to US469907A priority Critical patent/US2395109A/en
Application granted granted Critical
Publication of US2395109A publication Critical patent/US2395109A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0031Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0468Liquids non-physiological

Definitions

  • Another object is to provide an inhaler which is suitable for quantity production.
  • Another object is to provide an inhaler of the type employing a breakable glass container having a suitable covering which protects the user from injury and also prevents leakage of the contents.
  • Fig. 1 is a perspective view of the outer cartridge before the inner container has been inserted therein.
  • Fig. 2 is a side elevation, partly in section, of the inner container.
  • Fig. 3 is a longitudinal section through the assembled inhaler.
  • Fig. 4 is an end view thereof.
  • Fig. 5 is a perspective view similar to Fig. l, showing a further embodiment of the invention and Fig. 6 is a longitudinal section through the inhaler of Fig, 5.
  • the invention is shown as applied to an inhaler comprising an inner container or ampule II of frangible onion skin, glass or the like containing a liquid I such as aromatic spirits of ammonia, aromatic ammonia, amyl nitrite or other vaporizable substances.
  • a liquid I such as aromatic spirits of ammonia, aromatic ammonia, amyl nitrite or other vaporizable substances.
  • the ampule II is suiciently thin so as to be readily frangible by the pressure of the fingers.
  • the sealed ampule I I is placed within the outer cartridge I2 comprising an inner casing I4 of blotting paper, and an outer casing I of a denser paper, which may be moisture resistant.
  • the inner casing I4 is formed by a spirallyv wound, two ply white blotting paper strip with butted joint I3, and the opter casing I5 consists of a spirally wound strip of denser paper such as kraft paper or parchment paper which is wound around the inner casing I4 in a manner to provide a spiral groove I6 vbetween the adjacent side edges of the paper strip.
  • the groove I6, which is shown exaggerated in Fig. l, serves to expose a portion of the surface of the inner blotting paper casing I4 so as to permit and facilitate the escape of vapors after the ampule has been broken.
  • outer strip may be wound in such a manner that its edges nearly abut but are still sufficiently spaced to permit escape of vapors.
  • the helical joint line I3 of the inner casing I4 is preferably offset with respect to the spiral groove I6 of the outer casing I5.
  • a neutral vegetable adhesive such as a starch glue which does not retard the absorption or evaporation of the liquid when the ampule is broken.
  • the inner layer I4 preferably contains an indicator such as manganese sulphate, phenolphthalein, litmus, or the like, for the detection of leakage of the ammonia in the ampule. If manganese sulphate is used, for example, escaping ammonia vapors turn the container a brownish color and thereby indicate a defective ampule.
  • an indicator such as manganese sulphate, phenolphthalein, litmus, or the like, for the detection of leakage of the ammonia in the ampule. If manganese sulphate is used, for example, escaping ammonia vapors turn the container a brownish color and thereby indicate a defective ampule.
  • the cartridge I2 is preformed in the shape of an open end cylinder as shown in Fig. l. It is then closed at one end by crimping the material as indicated at 20 in Figs. 3 and 4.
  • the sealed ampule II containing the vaporizable material I0 is then placed in the open cartridge and the other end is closed by crimping as at 2
  • the cartridge protects the ampule from accidental breakage, although it is sufIiciently exible to permit the ampule to be readily fractured by squeezing the sides of the cartridge between the fingers. When broken the liquid is absorbed in the blotting paper layer I4 and the vapors readily escape through the openings I6 and from the unsealed ends 20 and 2
  • Figs. 5 and 6 The embodiment shown in Figs. 5 and 6 is y similar to that shown in Figs. 1 to 3, except that the outer layer 25 of Fig. 5 is continuous and is provided with a plurality of holes 26 which take the place of the openings I 6 of Fig. 1. These holes 26 expose the underlying layer of blotting paper and permit the escape of vapors in the manner above described.
  • the above device is well adapted to commercial production.
  • the outer cartridge may be readily formed and the ends crimped in by suitable packaging machinery.
  • the completed inhaler is suic'iently stiff and rigid to permit shipment and comparatively rough hanupon and being secured to said inner casing to stillen and protect the same Aand having its adjacent edges spaced to expose a helical portion of the outer surface of said blotting paper casing.
  • said inner casing consists of a spirally wound strip of blotting paper with abutting side edges.
  • said inner casing consists of a spirally wound strip of blotting paper with abutting side edges, the spiral butt joint between the adjacent edges of the blotting paper strip being offset in axial cartridge tightly enclosing said ampule, said cari tridge consisting of an inner casing formed of blotting paper and an outer casing formed of a' strip of moisture resistant paper spirally wound direction relative to said helical exposed portion -of the blotting paper casing surface.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Packages (AREA)

Description

Patented Feb. 19, 1946 PATEN T `OFllCf-fl .22,395,109
, INHALER iB. iEonda, Yonkers, :N. nl., 4assigner sto Burroughs Wellcome &\'Co. (fU.-SA.),.Inc.,-.New York, N. Y., a corporation 7Aof 4.New ."Inrk.
lApplication December 23, 194%,"SeralrNo469g907 3 Claims.v (Cl. 128-200) type having novel and improved characteristics.
Another object is to provide an inhaler which is suitable for quantity production.
Another object is to provide an inhaler of the type employing a breakable glass container having a suitable covering which protects the user from injury and also prevents leakage of the contents.
Various other objects and advantages will be apparent as the nature oi the invention is more fully disclosed,
The invention will be better understood by referring to the following description taken in connection with the accompanying drawing in which two embodiments thereof have been set forth for purposes of illustration.
In the drawing:
Fig. 1 is a perspective view of the outer cartridge before the inner container has been inserted therein.
Fig. 2 is a side elevation, partly in section, of the inner container.
Fig. 3 is a longitudinal section through the assembled inhaler.
Fig. 4 is an end view thereof.
Fig. 5 is a perspective view similar to Fig. l, showing a further embodiment of the invention and Fig. 6 is a longitudinal section through the inhaler of Fig, 5.
In the following description certain specic terms are used for convenience in referring to various details of the invention, but these terms are not intended to limit the scope of the invention except as dened by the claims. Referring to the drawing more in detail, the invention is shown as applied to an inhaler comprising an inner container or ampule II of frangible onion skin, glass or the like containing a liquid I such as aromatic spirits of ammonia, aromatic ammonia, amyl nitrite or other vaporizable substances. The ampule II is suiciently thin so as to be readily frangible by the pressure of the fingers.
The sealed ampule I I is placed Within the outer cartridge I2 comprising an inner casing I4 of blotting paper, and an outer casing I of a denser paper, which may be moisture resistant.
In the embodiment shown in Fig, 1 the inner casing I4 is formed by a spirallyv wound, two ply white blotting paper strip with butted joint I3, and the opter casing I5 consists of a spirally wound strip of denser paper such as kraft paper or parchment paper which is wound around the inner casing I4 in a manner to provide a spiral groove I6 vbetween the adjacent side edges of the paper strip. The groove I6, which is shown exaggerated in Fig. l, serves to expose a portion of the surface of the inner blotting paper casing I4 so as to permit and facilitate the escape of vapors after the ampule has been broken. It is to be understood that the outer strip may be wound in such a manner that its edges nearly abut but are still sufficiently spaced to permit escape of vapors. The helical joint line I3 of the inner casing I4 is preferably offset with respect to the spiral groove I6 of the outer casing I5.
All plies are secured together with a neutral vegetable adhesive, such as a starch glue which does not retard the absorption or evaporation of the liquid when the ampule is broken.
The inner layer I4 preferably contains an indicator such as manganese sulphate, phenolphthalein, litmus, or the like, for the detection of leakage of the ammonia in the ampule. If manganese sulphate is used, for example, escaping ammonia vapors turn the container a brownish color and thereby indicate a defective ampule.
The cartridge I2 is preformed in the shape of an open end cylinder as shown in Fig. l. It is then closed at one end by crimping the material as indicated at 20 in Figs. 3 and 4. The sealed ampule II containing the vaporizable material I0 is then placed in the open cartridge and the other end is closed by crimping as at 2|, Fig, 3. In this form the cartridge protects the ampule from accidental breakage, although it is sufIiciently exible to permit the ampule to be readily fractured by squeezing the sides of the cartridge between the fingers. When broken the liquid is absorbed in the blotting paper layer I4 and the vapors readily escape through the openings I6 and from the unsealed ends 20 and 2|.
The embodiment shown in Figs. 5 and 6 is y similar to that shown in Figs. 1 to 3, except that the outer layer 25 of Fig. 5 is continuous and is provided with a plurality of holes 26 which take the place of the openings I 6 of Fig. 1. These holes 26 expose the underlying layer of blotting paper and permit the escape of vapors in the manner above described.
It will be noted that-due to the simplicity of construction, the above device is well adapted to commercial production. The outer cartridge may be readily formed and the ends crimped in by suitable packaging machinery. Furthermore the completed inhaler is suic'iently stiff and rigid to permit shipment and comparatively rough hanupon and being secured to said inner casing to stillen and protect the same Aand having its adjacent edges spaced to expose a helical portion of the outer surface of said blotting paper casing. 2. An inhaler as claimed in claim 1, in which said inner casing consists of a spirally wound strip of blotting paper with abutting side edges.
1 l3I`An inhaleras claimed'in claim 1, in which said inner casing consists of a spirally wound strip of blotting paper with abutting side edges, the spiral butt joint between the adjacent edges of the blotting paper strip being offset in axial cartridge tightly enclosing said ampule, said cari tridge consisting of an inner casing formed of blotting paper and an outer casing formed of a' strip of moisture resistant paper spirally wound direction relative to said helical exposed portion -of the blotting paper casing surface.
HOWARD B. FONDA.
US469907A 1942-12-23 1942-12-23 Inhaler Expired - Lifetime US2395109A (en)

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Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2442004A (en) * 1945-01-29 1948-05-25 Hayward-Butt John Terry Inhaler for analgesic or anaesthetic purposes
US2705007A (en) * 1951-09-10 1955-03-29 Louis P Gerber Inhaler
US2966909A (en) * 1956-12-14 1961-01-03 A E Halperin Co Inc Pocket inhalator
US3463149A (en) * 1968-07-05 1969-08-26 Theodor Albu Nose air filter
US3856142A (en) * 1973-01-24 1974-12-24 Mine Safety Appliances Co Inhalant package
US4058425A (en) * 1973-07-16 1977-11-15 A-T-O Inc. Inhalant disperser
US4095596A (en) * 1976-11-26 1978-06-20 Smithkline Corporation Nasal inhaler
US4275820A (en) * 1977-12-16 1981-06-30 J. W. Small Personal repellent device
US5133458A (en) * 1991-04-01 1992-07-28 Siebe North, Inc. Ampule-type inhalant dispenser
FR2731911A1 (en) * 1995-03-20 1996-09-27 Paul Seyvos Inhaler for aromas from therapeutic products
US6062213A (en) * 1998-06-16 2000-05-16 Fuisz Technologies Ltd. Single unit dose inhalation therapy device
US20040124254A1 (en) * 2002-12-10 2004-07-01 Shiro Harada Diffuser for volatile material such as aromatic or chemical agent
US20040244793A1 (en) * 2003-06-09 2004-12-09 Wedel Victor J. Aroma inhaling product
US20060107959A1 (en) * 2003-10-29 2006-05-25 Plummer Willie Pressly Jr Mask having a scenting means, and method for blocking out unpleasant odors
US20060157578A1 (en) * 2002-12-10 2006-07-20 Lumica Corporation Diffuser for volatile material such as aromatic or chemical agent
US8631941B2 (en) 2010-04-22 2014-01-21 James Alexander Corporation Ampoule dispenser assembly and process

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2442004A (en) * 1945-01-29 1948-05-25 Hayward-Butt John Terry Inhaler for analgesic or anaesthetic purposes
US2705007A (en) * 1951-09-10 1955-03-29 Louis P Gerber Inhaler
US2966909A (en) * 1956-12-14 1961-01-03 A E Halperin Co Inc Pocket inhalator
US3463149A (en) * 1968-07-05 1969-08-26 Theodor Albu Nose air filter
US3856142A (en) * 1973-01-24 1974-12-24 Mine Safety Appliances Co Inhalant package
US4058425A (en) * 1973-07-16 1977-11-15 A-T-O Inc. Inhalant disperser
US4095596A (en) * 1976-11-26 1978-06-20 Smithkline Corporation Nasal inhaler
US4275820A (en) * 1977-12-16 1981-06-30 J. W. Small Personal repellent device
US5133458A (en) * 1991-04-01 1992-07-28 Siebe North, Inc. Ampule-type inhalant dispenser
FR2731911A1 (en) * 1995-03-20 1996-09-27 Paul Seyvos Inhaler for aromas from therapeutic products
US6062213A (en) * 1998-06-16 2000-05-16 Fuisz Technologies Ltd. Single unit dose inhalation therapy device
US20040124254A1 (en) * 2002-12-10 2004-07-01 Shiro Harada Diffuser for volatile material such as aromatic or chemical agent
EP1435246A1 (en) * 2002-12-10 2004-07-07 Lumica Corporation Compact diffuser for volatile material
US7048203B2 (en) * 2002-12-10 2006-05-23 Lumica Corporation Diffuser for volatile material such as aromatic or chemical agent
US20060157578A1 (en) * 2002-12-10 2006-07-20 Lumica Corporation Diffuser for volatile material such as aromatic or chemical agent
US7147171B2 (en) 2002-12-10 2006-12-12 Lumica Corporation Diffuser for volatile material such as aromatic or chemical agent
US20040244793A1 (en) * 2003-06-09 2004-12-09 Wedel Victor J. Aroma inhaling product
US20060107959A1 (en) * 2003-10-29 2006-05-25 Plummer Willie Pressly Jr Mask having a scenting means, and method for blocking out unpleasant odors
US7311105B2 (en) * 2003-10-29 2007-12-25 Plummer Jr Willie Pressly Mask having a scenting means, and method for blocking out unpleasant odors
US8631941B2 (en) 2010-04-22 2014-01-21 James Alexander Corporation Ampoule dispenser assembly and process

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