US2354334A - Germicide and method of producing same - Google Patents
Germicide and method of producing same Download PDFInfo
- Publication number
- US2354334A US2354334A US463543A US46354342A US2354334A US 2354334 A US2354334 A US 2354334A US 463543 A US463543 A US 463543A US 46354342 A US46354342 A US 46354342A US 2354334 A US2354334 A US 2354334A
- Authority
- US
- United States
- Prior art keywords
- molecular weight
- manganous
- reducing agent
- chlorophenol
- chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000002070 germicidal effect Effects 0.000 title description 9
- 238000000034 method Methods 0.000 title description 3
- 239000003638 chemical reducing agent Substances 0.000 description 11
- ISPYQTSUDJAMAB-UHFFFAOYSA-N 2-chlorophenol Chemical compound OC1=CC=CC=C1Cl ISPYQTSUDJAMAB-UHFFFAOYSA-N 0.000 description 10
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 9
- 239000000243 solution Substances 0.000 description 8
- 229910021380 Manganese Chloride Inorganic materials 0.000 description 7
- GLFNIEUTAYBVOC-UHFFFAOYSA-L Manganese chloride Chemical compound Cl[Mn]Cl GLFNIEUTAYBVOC-UHFFFAOYSA-L 0.000 description 7
- 229960002089 ferrous chloride Drugs 0.000 description 7
- 235000003891 ferrous sulphate Nutrition 0.000 description 7
- 239000011790 ferrous sulphate Substances 0.000 description 7
- NMCUIPGRVMDVDB-UHFFFAOYSA-L iron dichloride Chemical compound Cl[Fe]Cl NMCUIPGRVMDVDB-UHFFFAOYSA-L 0.000 description 7
- 235000002867 manganese chloride Nutrition 0.000 description 7
- 239000011565 manganese chloride Substances 0.000 description 7
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 description 6
- MVIOINXPSFUJEN-UHFFFAOYSA-N benzenesulfonic acid;hydrate Chemical compound O.OS(=O)(=O)C1=CC=CC=C1 MVIOINXPSFUJEN-UHFFFAOYSA-N 0.000 description 5
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 5
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 5
- 239000012895 dilution Substances 0.000 description 4
- 238000010790 dilution Methods 0.000 description 4
- 150000002989 phenols Chemical class 0.000 description 3
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 239000003518 caustics Substances 0.000 description 2
- 231100000518 lethal Toxicity 0.000 description 2
- 230000001665 lethal effect Effects 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
Definitions
- This invention relates to g'ermicides of the phenol group that are in oxidized form, such as chlorophenol and sulfophenol.
- the object of the invention is to greatly increase the germicidal properties of chlorophenol, sulfophenol, or-any of the solutions of phenol generally in which the phenol is in the oxidized form, thus tion, one gram molecular weight of a reducing agent, such as ferrous chloride, ferrous sulphate, manganous chloride or manganous sulphate.
- a reducing agent such as ferrous chloride, ferrous sulphate, manganous chloride or manganous sulphate.
- the killing power of the solution as applied to micro-organisms is substantially increased so that the per cent concentration of the resultant solution may be from one-third to one-half of the concentration required, before the addition, for accomplishing the same results.
- the objectionable causticity to tissue of the phenol is correspondingly reduced and the resultant product is less caustic to tissue.
- the concentration is such that it is caustic to tissue if it has the requisite killing power to be effective as a germicide, as demonstrated by the following; the least lethal dilution of chlorophenol is 1:500; the effective dilution is -l:100.
- the least lethal dilution of improved chlorophenol is 1:1400; the effective dilution is 1:460.
- the method of increasing the germicidal properties of phenols that are in oxidized form that comprises adding to each gram.
- molecular weight of the phenol one gram molecular weight of a reducing agent from the group; ferrous chloride, ferrous sulfate, "manganous chloride, manganous sulfate.
- a germicidal product comprising one of the phenols that is in oxidized form and areducing agent from one of the group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate, in the proportion of one gram molecular weight of the phenol to one gram molecular weight of the reducing agent.
- a germicidal product comprising one of the phenol in the group; chlorophenol, sulfophenol, and a reducing agent from one of the group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate, in the proportion of one gram molecular weight of the reducing agent to. each gram molecular weight of the phenol.
- a germicidal solution comprising one of the phenols in the group; chlorophenol, sulfophenol and a reducing agent from one of the group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate, in the proportion of onev gram molecular weight of the reducing agent to each gram molecular weight of the phenol.
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Agronomy & Crop Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Description
Patented July 25, 1944 I v 2,354,334 onmvncma AND MElHOD or PRODUCING Anthony J. Salle, West Los Angeles, as Howard L. Guest, Ocean Park, hall to Leo A. Gunther, Robbins, Calif.
No Drawing. Application October 27, 1942, Serial No. 463,543
7 Claims. (Cl. 167-31) This invention relates to g'ermicides of the phenol group that are in oxidized form, such as chlorophenol and sulfophenol.
The object of the invention is to greatly increase the germicidal properties of chlorophenol, sulfophenol, or-any of the solutions of phenol generally in which the phenol is in the oxidized form, thus tion, one gram molecular weight of a reducing agent, such as ferrous chloride, ferrous sulphate, manganous chloride or manganous sulphate.
By the above addition of the reducing agent, the killing power of the solution as applied to micro-organisms, such as Staphylococcus aureus, is substantially increased so that the per cent concentration of the resultant solution may be from one-third to one-half of the concentration required, before the addition, for accomplishing the same results.
By thi addition, the objectionable causticity to tissue of the phenol is correspondingly reduced and the resultant product is less caustic to tissue.
It is pertinent to note that in a conventional solution of chlorophenol, without the addition of a reducing agent, the concentration is such that it is caustic to tissue if it has the requisite killing power to be effective as a germicide, as demonstrated by the following; the least lethal dilution of chlorophenol is 1:500; the effective dilution is -l:100. The least lethal dilution of improved chlorophenol is 1:1400; the effective dilution is 1:460.
The advantages of the invention are therefore,
., assignors of one- 2. The method of increasing the germicidal properties of phenols that are in oxidized form that comprises adding to each gram. molecular weight of the phenol one gram molecular weight of a reducing agent from the group; ferrous chloride, ferrous sulfate, "manganous chloride, manganous sulfate.
3. The method of increasing the germicidal property of one of the group; chlorophenol, sulfophenol, that comprises adding to each gram molecular weight thereof one gram molecular weight of one ofthe group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate.
4. A germicidal product comprising one of the phenols that is in oxidized form and areducing agent from one of the group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate, in the proportion of one gram molecular weight of the phenol to one gram molecular weight of the reducing agent.
5. A germicidal product comprising one of the phenol in the group; chlorophenol, sulfophenol, and a reducing agent from one of the group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate, in the proportion of one gram molecular weight of the reducing agent to. each gram molecular weight of the phenol.
6. A germicidal solution comprising one of the phenols in the group; chlorophenol, sulfophenol and a reducing agent from one of the group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate, in the proportion of onev gram molecular weight of the reducing agent to each gram molecular weight of the phenol.
7. A germicidal solution having substantially the same killing power to Staphylococcus aureus -of a 1:100 solution of chlorophenol that comprises substantially a 1:1400 solution of chlorophenol and a reducing agent from one of the group; ferrous chloride, ferrous sulphate, manganous chloride, manganous sulfate, in the proportion of one gram molecular weight of the reducing agent to each-gram molecular weight of .45 the chlorophnol.
ANTHONY J. SALLE. HOWARD L. GUEST.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US463543A US2354334A (en) | 1942-10-27 | 1942-10-27 | Germicide and method of producing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US463543A US2354334A (en) | 1942-10-27 | 1942-10-27 | Germicide and method of producing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US2354334A true US2354334A (en) | 1944-07-25 |
Family
ID=23840470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US463543A Expired - Lifetime US2354334A (en) | 1942-10-27 | 1942-10-27 | Germicide and method of producing same |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US2354334A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2585965A (en) * | 1946-03-01 | 1952-02-19 | Anthony J Salle | Iodine solution comprising an oxidation-reduction system |
-
1942
- 1942-10-27 US US463543A patent/US2354334A/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2585965A (en) * | 1946-03-01 | 1952-02-19 | Anthony J Salle | Iodine solution comprising an oxidation-reduction system |
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