US2341198A - Automatic immersion apparatus - Google Patents

Automatic immersion apparatus Download PDF

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US2341198A
US2341198A US477793A US47779343A US2341198A US 2341198 A US2341198 A US 2341198A US 477793 A US477793 A US 477793A US 47779343 A US47779343 A US 47779343A US 2341198 A US2341198 A US 2341198A
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shaft
holder
motor
receptacles
receptacle
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US477793A
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Edwin C Weiskopf
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31Apparatus therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31Apparatus therefor
    • G01N2001/315Basket-type carriers for tissues

Definitions

  • the means for rotating the tissueor other material holder in the liquid container is more directly associated with the tissue holder.
  • the operation of the apparatus for moving the tissue or other material holder from one receptacle into another is accomplished by a vertical upward movement of the main shaft, to raise the holder above the top of the receptacle in which the holder was positioned, a turning movement of said shaft, for positioning the holder over the receptacle in which the holder is to be next positioned, and a downward vertical movement of the shaft for lowering the holder into said last mentioned receptacle where said holder remains until the next operating cycle which is initiated under the control of a timing device.
  • Fig. 1 is a view, partly in elevation and partly of an. automatic immersion apparatus position ofge parts when the tissue holder is immersed in ne of the liquid receptacles;
  • Fig. 2 is a view similar to Fig. 1 showing the position of the parts in which the tissue holder is raised above the receptacle to permit transfer thereof to another liquid receptacle or to obtain access to the holder;
  • Fig. 3 is a sectional view, on a larger scale, of the device for supporting and rotating the tissue holder;
  • Fig. 4 is a detail sectional view on the line 4-4 of Fi 3;
  • Fig. 5 is a sectional view on the line 55 of Fig. 1'; I
  • Fig. 6 is a front view of the apparatus
  • Fig. 7 is a circuit diagram
  • Fig. 8 is a top view of the apparatus
  • Fig. 9 is a view taken along the line 9-9 of Fig. 1,-one of the movable parts being in a different position for clearness of illustration;
  • Fig. 10 is a top plan view, partly in section, on the line Ill-l0 of Fig. 1;
  • Fig. 11 is a sectional view on the line H-ll of Fi 10;
  • Fig. 12 isa detail sectional lZ-l2 ofFig. 11;
  • Fig. 13 is a sectional view on a larger scale of parts of the mechanism illustrated in Flg. 11;
  • Fig. 14 is a view similar to Fig. 13 showing a modification; I r
  • Fig. 15 is a front view of the timing device
  • Fig. 16 is a rear view thereof
  • Fig. 17 is a sectional view on the line ll-i'l of Fig. 15 but shows the cam of the timing disk in a different position;
  • Fig. 18 is a front view .of part of the timing device illustrated in Fig. 15, showing the position view on the line of certain of the parts, when the device is operated independently of the notches in.the timing disk;
  • Fig. 18A is an enlarged detail sectional view on the line I8a-l6a of Fig. 15.
  • the automatic immersion apparatus embodying the present invention comprises, as disclosed in my above mentioned patent, a cabinet I6 on which a receptacle table or support 12 is mounted for supporting a plurality of receptacles I4 for the various liquids in which the tissue or other material subjected to treatment thereby is immersed.
  • Said receptacles are removably positioned in the trays I5 which are fixed to table I2.
  • a illustrated in Fig. 8. said receptacles are arranged in a circle on support I2.
  • a vertical shaft I6 is mounted at the center of said circle for longitudinal and rotary movement and has fixed thereto near its upper end a frame I6 which is raised and lowered by the vertical upward and downward movements, respectively, of said shaft, and which is turned with said shaft duringthe rotation thereof.
  • Said frame comprises a circular plate or disk 26 to which is secured a plurality of arms 22 which are circumferentially spaced and extend radially from the center of the circle. The inner ends of said arms are fitted in companion grooves 24 in which they are secured in any suitable way as by screws 26.
  • arms 22 extend to positions in which they lie over the receptacles I4, and the outer end of each of said arms is provided with a slot 28 which terminates at its inner end in an enlarged circular part 36, as illustrated in Fig. .8, from which the head 32 of one of the receptaclecover supporting rods 34 has been omitted in order to illustrate the shape of said slot. (See also Fig. 4.)
  • the rods 34 which carry the receptacle covers 36 are provided with reduced portions 36 to permit the attachment and removal of said rods 34 to and from the companion arms 22, substantially as described in my above mentioned patent.
  • the mechanism for operating shaft I6 for moving the same vertically and for turning the same between the upward and. downward movements in said shaft is operated by the electric motor M (Fig.
  • the rotary shaft of said motor is provided with a worm gear 46 which meshes with a worm wheel 42 fixed to a shaft 44 which is jour- 5 nailed for rotation in bearings 46 and 46 (Fig. 9).
  • a worm gear 50 is fixed to shaft 42 and meshes with a worm wheel 52 fixed to a shaft 54 journalled for rotation in a frame 56 mounted on the base 56 of the cabinet.
  • a link 66 is pivotally connected at its opposite ends to worm wheel 52 and to a cross head 62.
  • Said cross head 62 has a circular tubular opening 64 in which the lower circular portion I6aof shaft I6 is slidably and rotatably movable.
  • Said lower portion l6a of shaft I6 is of reduced diameter providing said shaft with a shoulder 6-6 (Fig. 11) which is engaged by the upper edge of cross head 62. It will be understood that when cross head 62 is moved upwardly by link 66, shoulder 66 of shaft I6 is engaged by the upper end of cross head 62 and the shaft is thereby raised as is also operated cross head 62, being movable downwardly independently of said shaft, exerts no downward pull thereon.
  • Cross head 62 is provided with rollers 68 which engage a guide bar 16 fixed in the standard 12, said rollers 68 and bar 10 constituting means for guiding cross head 62 in its vertical up and down movements.
  • is provided to ease the shock in the event that shaft I6 is suspended above cross head 62 out of supporting relation therewith.
  • Shaft I6 is rotated intermittently by a Geneva gear mechanism as explained in my above mentioned patent.
  • Said Geneva gear mechanism comprises a gear 14 which surrounds shaft l6 and through which said shaft is longitudinally movable.
  • Gear 14 is rotated by a cooperating Geneva gear member 16 which is actuated by the vertical shaft 16 from shaft 54 through the companion bevel gears 66 and 62.
  • This Geneva gear mechanism i of the same construction and operates in the same way as the Geneva gear mechanism illustrated and described in my above mentioned patent, but in the present construction provision is made for preventing rotation of shaft I6 during any cycle of operation of the apparatus, as may be desired.
  • the pin 64 which is fixed to and is operated by the cooperating Geneva gear member 16 and which normally engages in the slots 66 of gear 14 for imparting a partial rotation thereto between the raising and lowering of the shaft, is retractable to prevent its engagement in said slots when a turning movement of shaft I6 is not desired.
  • pin 84 is mounted for movement in a bracket 88 which is fixed to the bar rotated by gear 16 (Fig. 13).
  • Pin 64 is held in normal position by a spring 62 for engagement with slots 66 during the rotation of gear 16 for rotating gear 14, and is movable to a retracted position in which said pin is located above the upper surface of gear 14 so that it is incapable of engaging in the slots 66 of said gear.
  • Pin 64 is provided with a cross pin 64 which engages the top of bracket 66 when the pin is moved to its retracted position and given a partial turn to bring said cross pin ,64 out of registry with the slot 66 provided in bracket 66 (Fig. 11).
  • pin 84 is moved upwardly to a point above the upper edge of bracket 66,
  • cross pin 64 moving out of slot 66, and pin 64 the frame l6 which is carried thereby.
  • shaft I 6 said frame I8 and the parts carried by said frame and by said shaft move downwardly by gravity, without any downward pull on said shaft by cross head 62.
  • said pin 84 is turned so that its cross pin 64 registers with slot 66 whereupon spring 62 moves pin 84 downwardly to its normal projected position for engagement with slots 66 during the rotation of gear 16.
  • the holder 66 is carried by the supporting and rotating device indicated generally by the numeral I06 in Figs. 1, 2 and 3. Said device is mounted on and is movable with frame It being it is rotatable independently of said plate.
  • bracket I02 movably fits when the-bracket is mounted thereon.
  • Said bracket is also provided with a tubular opening I06 in jwhich a pin I08 of circular cross section is longitudinally and rotatably movable.
  • 'Ifheupper end of pin I08 is provided with adjustable nuts H and H2, nut IIO engaging the upper edge 4 of bracket I02 when pin I08 is in its normal position.
  • the lower end of pin I08 is provided with a reduced portion I I6 which is small enough to pass through the narrow part of slot 28. to permit bracket I02 to be mounted on and removed from the companion carrying arm 22.
  • bracket I02 is too large to pass through slot 28 but fits in the inner larger end portion of said slot and thus releasably holds bracket I02 against movement longitudinally of arm 22. It will be I understood that when it is desired to remove bracket I02 from arm 22, pin I08 is raised to the position illustrated in Fig. 3 in which pin portion H6 is in alignment with slot 28, so that bracket I02 can be moved outwardly of arm 22.
  • bracket I02 when it is desired to assemble bracket I02 on'any one of the arms 22, pin I08 is raised to align portion II6 thereof with slot 28, thus allowing the bracket to be moved longitudinally inwardly of the outer end of arm 22 to a position in which the pin engages the inner end of the slot, after which pin I08 is lowered in the larger part 30 of slot 28 for holding the bracket releasably in correct position onarm 22 and against movement longitudinally of said arm in either direction.
  • a motor-carrier H8 is supported by the lower end of pin I08 being removably secured to said pin by nuts I20 and I22 threaded end of said pin and positioned at opposite sides of the cover I24 of said motor-carrier II.8.
  • Said carrier is in the form of a housing for the electric motor MI and includes in addition to the cover I24 a plate I26 towhich said motor is fixed. Cover I24 is secured to plate I26 in any suitable way as by screws I28 and completely encloses said motor.
  • a vertical shaft I30 is rotated by motor Ml through suitable reduction gearing and extends through plate I26 in whicg bracket I32 is fixed to and rotatable by shaft I30.
  • Said bracket is provided with down turned end portions I34 provided with" apertures I36 in which laterally projecting pins I38 carried by holder 98 are removably engaged.
  • a spring member I40 is fixed to bracket I32 and imparts sufficient resiliency to said bracket to allow end portions I34 thereof to be sprung over pins I38 and to permit the disengagement of said pins from the apertures I36 of the bracket for connecting and disconnecting holder98 to and from bracket I32.
  • motor MI is connected to an electric outlet device I42 which is supplied with current through a switching and control device I44.
  • the outlet device I42 on the lower is in fixed relation to shaft I6.
  • outlet device I42 is secured to the hub portion I46 of frame I8 in any suitable way as by set screws I48, said hub portion being secured to shaft I6 by set screws I50.
  • a collar I52 is secured to shaft I6 by said screws I54 below outlet device I42 for limiting thedownward movement of frame I8 on said shaft I8 and thereby assisting in the positioning of said frame on;
  • Outlet device I42 is provided with a pair of relatively insulated continuous metal rings I56 and I58 which are electrically connected in parallel to a plurality of outlet sockets I60.
  • An electric plug I62 at the end of an electric cord I64-connected to motor MI is receivable in any one of said sockets for connecting said motor to a source of power when the outlet device is energized through device I44 as will'now be described.
  • the switching and control device I44 is mounted in fixed position below the outlet device I42.
  • said device I44 comprises a horizontal plate I66 which fits over and is fixed to the stationary guide bearing I68 in which shaft I6 is movable.
  • Said part I66 of device I44 has an integral collar I10 which is fixed to shaft guide I68 in any suitable way, as by one or more set screws I12.
  • a pair of spring projected metal pins I14 and I16 are carried by'plate I66 in position to engage conductor rings I56 and I58 of outlet device I42 when shaft I6 is moved downwardly and is near the end of its downward travel, and a switch I18 is carried by plate I66 in position to be operated by the bottom of outlet I42 when shaft I6 is at the end of its downward travel.
  • Said switch is a normally open switch and as here shown is provided with a pin I80, which is moved downwardly against the action of a spring (not shown) contained in said switch. It will be'understood that contact pins I14 and I16 are in series with the contacts of switch I18 so that an electric potential is applied to said contact pins I14 and I16 when switch I18 is closed. Further it will be understood that when contact rings I56 and I56 engage pins I14 and I16, respectively, and switch I18 is closed, which is the condition illustrated in Fig. 1 of the drawings, current is supplied to the outlet device I42 for application to motor MI for rotating the holder 98.
  • pins I14 and I16 are engaged before switch I18 is closed and are disengaged after switch I18 is opened, thus eliminating sparking at the contacts between the conductor rings I56, I58 and the com;- panion contact pins I14, I16.
  • the apparatus is provided with only one holder rotating and supporting device I00, there is provision for utilizing additional holder rotating and supporting devices so that if desired a plurality of holders may be simultaneously positioned in different receptacles, respecbe noted, that when the carrier H8 is moved downwardly pursuant to the downward movement of frame I8 by shaft I6, the lower surface of plate I26 may engage the top edge of the companion receptacle, and this can occur before the downward movement of shaft I6 is completed, since motor-carrier II 8 is supported by the pin I08 which is slidable in bracket I02.
  • the apparatus is operated under the control of a timing device I82 having a notched control disk I84, as described in my 'above mentioned Letters Patent.
  • Said timing device I82 is positioned within cabinet I (Figs. 6 and 10) and the cabinet is provided with a hinged door I86 having a transparent window I88 through which timing disk I84 and other parts of the timing device are visible.
  • the circuit of motor M is completed and interrupted at the proper times by the timing devices I82 substantially in the same way as described in my above mentioned patent, except that in lieu of the mercury switches disclosed in said patent there are utilized in the present apparatus double-throw micro-switches I 90 and I92, switch I90 being operated by the timer I82 and switch I92 being operated bya cam I94 rotated by shaft 54.
  • the timing disk I84 is provided with peripherally spaced notches I96 separated by continuous peripheral or circumferential edge portions of the disk. Said timer disk is removably secured to a plate I98 which is rotated by the shaft of an electric clock-motor 200
  • a lever 202 is secured to a spindle 204 which is mounted for turning movement in a bearing 206 in the frame 208 of the timing device.
  • Said lever has a part 2I0 which engages the peripheral edge of timing disk I84 and which is movable successively into notches I96 during the rotation of said timing disk of clock-motor 200.
  • An arm H2 is fixed to spindle 204 (Figs.
  • Said arm H6 is provided with a notch 224, in which a pin 226 carried by lever 202 is engaged for limiting the pivotal movement of lever 202 in a counter-clockwise direction.
  • Said arm M6 is also provided with a notch 228 in which pin 226 is engaged when lever 202 is moved to its retracted position by the cam 230 at the end of one rotation of cam disk I84, that is at the completion of the operation of the apparatus as described in my above mentioned patent.
  • part 2I0 of lever 202 is pivotally connected to the adjacent end of the main part 232 of said lever by a pivot pin 234.
  • part 2I0 has a recessed portion 236 in which the adjacent end of part 232 is pivotally connected by said pin 234..
  • a spring 238 fixed to part 232 bears on part 2I0 for holding the latter in normal position.
  • lever 202 When it is desired to actuate motor M for raising shaft I6 before part 2I0 engages the timing disk I84 in a notch thereof, lever 202 is turned counterclockwise, part 2I0 being pivoted downwardly against spring 238 allowing lever 202 to move in a counter-clockwise direction by the amount necessary to permit the operation of micro-switch I90, this operation being the equivalent of the operation of said switch I when part 202 engages in a notch I 96 in the timing disk.
  • the apparatus can be operated, if desired, before a notch of the disk is aligned with part 2
  • the pin 84 of the Geneva gear mechanism will be moved to its retracted position so that shaft I8, although rotated by gear wheel 52 when motor M is actuated, would be ineffective to actuate the Geneva gear mechanism for turning shaft I6.
  • movablecontact member 240 When movablecontact member 240 is moved from its stationary contact member 244 to its other stationary contact member 246, that is to its dotted line position, a circuit is completed through said movable contact member 240, the stationary contact member 246, from the latter over the wire connection 248 to the stationary contact member 250 of switch I92, which is then engaged by the movable contact member 242 of switch I92, it being understood that the dotted line position of movable contact member 240 of switch I90 illustrates the position thereof when part 2I0 of lever 202 engages disk I84 in a notch I96. As soon as movable contact member 246 of switch I60 is in the dotted line position illustrated in Fig.
  • Geneva gear by reason of its construction and operation is effective to turn shaft l6 only after said shaft has raised holder 98 out of the receptacle, and that as soon as this occurs said Geneva gear operates to turn said shaft for moving holder 98 laterally to a position over the next receptacle, after which.
  • Fig. 14 of the drawings there is illustrated a different form of device for rendering the Geneva gear mechanism inoperative for turning shaft I6.
  • Any suitable means may be provided for releasably holding lever 264 in its dotted line position to which it has moved for rendering the Geneva gear mechanism inoperative to turn shaft l6.
  • this means may comprise a projection 210 on arm 266 which engages over the upper edge 212 of lever 264 when said lever is depressed, there being sufficient play between the parts to permit the disengagement of projection 210 from lever 264 when it is desired to restore the mechanism to its normal condition.
  • This interruption of the timing device may be desirable when the clock-motor is a one-hour or other short period clock, so that the disk makes one revolution in a comparatively short period and the time consumed inv moving the holder from one receptacle to another is large in comparison to the time of one revolution of the timing disk.
  • a normally closed switch 256 (Fig. 1) is provided in the circuit of clock-motor 200, and is held closed by a cam 258 operated by shaft 54.
  • shaft 18a which corresponds to the shaft 18 described above is provided with a coupling member or socket 256 having a square or other non-circular recess 256 in which the coupling member 260 of shaft 262 is releasably engageable, said coupling member 260 being preferably of the same cross sectional configuration as the recess 258 of coupling 256 and being slidable into and out of said recess.
  • the upper end of shaft 262 is fixed to the gear 16, and when coupling member 260-15 engaged with coupling member 256 operated by shaft 18a, shaft 2621s rotatable by shaft 18w for operating the Geneva. gear mechanism in the normal way.
  • shaft 262 is raised for disconnecting coupling 260 from coupling 256 and for moving gear 16 and the slot-engaging pin 84a to positions above Geneva gear I4.
  • a lever 264 is pivotally mounted on an arm 266 fixed to coupling 255 and engages under a collar 266 fixed to shaft shaft 54 begins to rotate, at the start of the cycle in which shaft I6 is actuated, said cam disengages said switch 256 and the latter opens thereby interrupting the circuit of clock-motor 200, and at the completion of one rotation of shaft 54, i.
  • cam 258 engages switch 256 and closes the same, thus completing the circuit through motor 200 for operating the timing device.
  • a by-passing switch 260 is provided in the circuit of motor 200 (see Fig. 7). This switch is normally open so that motor 200 is controlled by switch 256, but when it is desired to eliminate the control of switch 256, switch 260 is closed and the timing device is in that case operated continuously.
  • apparatus of the class described comprising a plurality of receptacles, a holder movable into and out of said receptacle, and means for effecting relative vertical and lateral movements of said holder and receptacle for conveying said holder out of one of said receptacles and into another of said receptacles; means for rotating said holder in one of said receptacles when the holder is positioned therein comprising a carrier mounted for movement laterally of said receptacles and toward and away from said receptacles in vertical line therewith, respectively.
  • a motor mounted on said carrier and movable therewith to positions over and in line with said receptacles, a vertical shaft mounted for rotation in said carrier and connected to said motor for rotation thereby, and means for connecting said holder to said shaft for rotation thereby.
  • apparatus of the class described comprising a plurality of receptacles, a holder movable into and out of said receptacles, and means for effecting relative vertical and lateral movements of said holder and receptacle for conveying said holder out of one of said receptacles and into another of said receptacles
  • means for rotating said holder in one of said receptacles when the holder is positioned therein comprising a carrier mounted for movement laterally of said receptacles and toward and away from said receptacles in vertical line therewith, respectively, a motor mounted on said carrier and movable therewith to positions over and in line with said receptacles, a vertical shaft'mounted for rotation in said carrier and connected to said motor for rotation thereby, and means for connecting said holder to said shaft for rotation thereby
  • said carrier comprising a plate adapted to seat upon and cover the receptacle in which said holder is positioned.
  • apparatus of the class described comprising a plurality of receptacles arranged in a circle, a shaft disposed vertically at the center of said circle and mounted for rotation and for vertical movement, a member extending radially from said shaft above said receptacles and movable by said shaft toward and away from said receptacles and laterally thereof, and a holder movable under the control of said member into and out of said receptacles; means for rotating said holder when the latter is positioned in one of said receptacles comprising a carrier mounted on said member and movable therewith to positions over said receptacles, respectively, in vertical alignment therewith, a motor supported on said carrier, a vertical shaft mounted for rotation in said carrier and rotatable by said motor, and means for connecting said holder to said last mentioned shaft for rotation thereby when said holder is positioned in one of said receptacles.
  • apparatus of the class described comprising ng aplurality of receptacles arranged in a circle, a shaft disposed vertically at the center of said circle and mounted for rotation and for vertical movement, a member extending radially 5 from said shaft above said receptacles and movable by said shaft toward and away from said receptacles and laterally thereof, and a holder movable under the controlof said member into cal alignment therewith, a motor supported on said carrier, a vertical-shaft mounted for rotation in said carrier and rotatable by said motor, and means for connecting said holder to said last mentioned shaft for rotation thereby when said holder is positioned in one of said recep- 7 tacles, said carrier comprising a plate adapted to cover the receptacle in which said holder is positioned.
  • apparatus of the class described compriscle, a shaft disposed vertically at the center of said circle and mounted for rotation and for vertical movement, a member extending radially from said shaft above said receptacles and movable by said shaft toward and away from said,
  • a holder movable under the control of said member into and out of said receptacles; means for rotating said holder when the latter is positioned in one of said receptacles comprising a carrier mounted on said member and movable therewith to positions over said receptacles, in vertical align ment therewith, respectively, a motor supported on said carrier, a vertical shaft mounted for rotation in said carrier and rotatable by said motor, and means for connecting said holder to said last mentioned shaft for rotation thereby when said holder is positioned in one of said recepta-,
  • holder for movement into and out of said receptacle through said open-top thereof, said holder being also mounted for rotation in said receptacle; means for rotating said holder and for supporting the same, comprising a bracket, a frame supported by said bracket, a motor carried by said,
  • apparatus of the class described comprising an open-top receptacle, a holder mounted for movement into and out of said receptacle through said open-top thereof, said holder being also mounted for rotation in said receptacle; means for rotating said holder and for supporting the same comprising a horizontal arm mounted for vertical movement, a bracket removably supported by said arm, a frame supported by said bracket, 9. motor carried by said frame, a shaft mounted for rotation in said frame and rotatable by said motor, and means for connecting said holder to said shaft for rotation thereby.
  • apparatus of the class described comprising an open-top receptacle, a holder mounted for movement into and out of said receptacle through said open-top thereof, said holder being also mounted for rotation in said receptacle; means for rotating said holder and for supporting the same comprising a horizontal arm mounted for vertical movement, a bracket removably supported by said arm, a frame supported by said bracket, a motor carried by said frame, a shaft mounted for rotation in said frame and rotatable by said motor, and means for connecting said holder to said shaft for rotation thereby, said arm having a slotted part, said bracket having an opening in which the slotted part of the arm fits, said bracket having another opening extending at right angles to said first mentioned opening, a member carried by said bracket and having a limited movement in said other opening, said member having a part ing a plurality of receptacles arranged in a cirit which is narrow eno gh t pa t r h sa n rrow part
  • apparatus of the class described comprising an open-top receptacle, and a holder mounted for movement into and out of said receptacle through said open-top thereof, said holder being also mounted for rotation in said receptacle; means for rotating said holder and for supporting the same comprising a horizontal arm mounted for vertical movement, a bracket removably supported by said arm, a plate carried by said bracket and adapted to engage at one side thereof the top of the receptacle when said holder is positioned therein, -a motor positioned at the other side of said plate, a shaft operated by said motor extending throughisaid plate to said first mentioned side thereof, and means at said first mentioned side of said plate for connecting said holder to said shaft for rotation thereby.
  • the sub-combination comprising an arm having,a slot in its end, said slot having a narrow part extending inwardly from the end of said arm to a wider part at the inner end of the slot, a bracket supported by said arm and having an opening in which the slotted part of the arm fits, said bracket having another opening extending at right angles to said first mentioned opening, a member carried by said bracket and having a limited movement in said other opening, said member having a part which is narrow enough to pass through said narrow part of said slot and a wider part which cannot pass through said narrow part of said slot but which can project through said wider part of said slot, said member being movable in said other opening of the bracket to one position in which said narrow part of the member is in line with said narrow part of the slot for movement therein and to a position out of line with said narrow part of the slot, said bracket being removable from said arm in said first position of said member and held against removal from said arm in the second position of said member.
  • a shaft mounted for rotation and for vertical movement, means for rotating said shaft, and means for raising said shaft
  • said last mentioned means including a part with respect to which said shaft is longitudinally movable and which in a predetermined relative position of said shaft and said part is engageable with said shaft for raising the same, said part being movable upwardly for raising said shaft and movable downwardly longitudinally of said shaft in relation thereto whereby said part is prevented from exerting a downward force on said shaft when said part moves downwardly faster than said shaft.
  • a shaft mounted for rotation and for vertical movement, means for rotating said shaft, and means for raising said shaft
  • said last mentioned means including a part with respect tov which sad shaft is longitudinally movable and which in a predetermined relative position of said shaft and said part is engageable with said shaft for raising the same, said part being movable upwardly for raising said shaft and movable downwardlylongitudinally of said shaft in relation thereto whereby said part is prevented from exerting a downward force on said shaft when said part moves downwardly faster than said shaft, said shaft being normally supported by said part, and means for resiliently opposing the downward movement of said shaft when said part is moved out of supporting relation thereto.
  • a timing disk having a peripheral edge provided with peripherally spaced edge notches and a switch, operable under the control of said disk; means actuated by said disk for actuating said switch comprising a pivotally mounted member having a part engageable with said disk in said notches and with the peripheral edge portions of the disk between said notches, means biasing said member to hold said part in engagement with said disk, said member having a part to which said disk-engaging part is movably secured for movement relatively to said last mentioned part in directions toward and away from the peripheral edge of the disk, and means biasing said disk-engaging part for movement relatively to said last mentioned part toward the peripheral edge of said disk.
  • a timing disk having a peripheral edge provided with peripherally spaced edge notches and a switch operable under the control of said disk; means actuated by said disk for actuating said switch comprising a pivotally mounted member having a part engageable with said disk in said notches and with the peripheral edge portions of the disk between said notches, means biasing said member to hold said part in engagement with said disk, said member having a part to which said disk-engaging part is pivotally secured for movement relatively'to said last mentioned part in directions toward and away from the peripheral edge of the disk, and spring means biasing said disk-engaging part for movement relatively to said last mentioned part toward the peripheral edge of said disk.
  • an automatic immersion apparatus having a shaft mounted for rotation and for vertical movement, means for moving said shaft in a vertical direction, and means including a Geneva gear mechanism for intermittently turning said shaft in timed relation to the vertical movement thereof, means for rendering said Geneva gear mechanism inoperative to turn said shaft whereby said shaft is movable vertically but not rotatably, said last mentioned means comprising companion parts of said Geneva gear mechanism mounted for relative vertical movement from positions in which said parts are engageable with each other for turning said shaft to positions in which. said parts are in inoperative relation.
  • an automatic immersion apparatus having a shaft mounted for rotation and for vertical movement, means for moving said shaft in a vertical direction, means for imparting a rotary movement to said shaft in timed relation to the vertical movement thereof, and means for actuating both of said shaft-moving means, means for rendering said last mentioned means inoperative to actuate said shaft rotating means but without rendering the same inoperative to actuate said first mentioned shaft moving means whereby the shaft is movable vertically without rotation thereof, said means for rendering said actuating means inoperative as aforesaid comprising a rotary member actuated by said actuating means, a companion rotary member normally' in engagement with and rotated by said first mentioned rotary member and movable out of operative engagement therewith, and means for moving said companion rotary member out of operative engagement with said first mentioned rotary member.
  • Apparatus of the class described comprising a plurality of receptacles arranged in a circle, a shaft mounted vertically at the center of said circle for rotation and for vertical movement upwardly and downwardly, a horizontal frame fixed to and movable with said shaft, said frame comprising an arm extending radially from said shaft toward said receptacles, an electric-outlet device carried by said shaft below said frame, said outlet comprising a pair of slip rings and a socket connected thereto, a switching device positioned in fixed position below said outlet device, said switching device comprising a switch which is opened and closed by'upward and downward movements, respectively, of said 5 shaft, said switching device comprising also a pair of conductors electrically connected to said switch and engageable with and disengageable from said slip rings when said shaft moves downwardly and upwardly, respectively, a motor sup- 10 ported by said arm and connected to said socket of the outlet device, and a holder supported by said arm and rotatable by said motor, said holder being movable

Description

Feb. 8, 1944. I c WERSKOPF 2,341,198
AUTOMATIC IMMERSION APPARATUS Filed March 3, 1943 6 Sheets-Sheet 1 Franz Feb. 8, 1944. c, wElSKCPF 2,341,198
AUTOMATIC IMMERSION APPARATUS 6 Sheets-Sheet 3 Filed March 3, 1943 IN VEN TOR.
Feb. 8, 1944. E. c. WEISKOPF AUTOMATIC IMMERSION APPARATUS Filed March 3, 1943 6 Sheets-Sheet 4 IN VEN T OR. 60a; 0. MM BY 63L AZTF/WI Feb. 8, 1944. E. c. WEISKOPF 2,341,198
AUTOMATIC IMMERSION APPARATUS Filed March 3, 1943 s Sheets-Sheet 5 III/1 IN VEN TOR.
ATIWMIZ Feb. 8, 1944. E. c. WEISKOPF AUTOMATIC IMMERSIQN APPARATUS Filed March 5, 1943 6 Sheets-Sheet 6 IN VEN TOR.
Pram-i Fee. a, 1944 STATES PATENT OFF-ICE 2,341,198 AUTOMATIC IMMEBSION. APPARATUS Edwin C. Weiskopf, New York, N. Y. Application March 3, 1943, Serial No. 477,793
17 Claims. (Cl. 91-46) This invention relates to automatic immersion apparatus of the type disclosed in my United States Letters Patent No. 2,157,875 granted May 9, 1939, and the present application is a continuation inipart of my application, Ser. No. 402,787 filed July 17, A941 for Automatic immersion apparatus.
In the apparatus of the present invention, provision is made for immersing the tissue or other materials or articles in various liquids and for rotating the tissue or other material container in the liquid or liquids whereby to improve the action vof the liquids on the tissue or other materials as set forth in my above mentioned prior application. In accordance with the present in vention, the means for rotating the tissueor other material holder in the liquid container is more directly associated with the tissue holder. Also, in accordance with this invention, provision is made in the apparatus for locating the holder rotating means at any one of a number of selected points, that is at any one of a number of liquid receptacles. Further, in accordance with the present invention, provision is made for the rotation of a plura 'ty of holders in a plurality of liquid receptacles, respectively.
- As described in my above mentioned Letters Patent, the operation of the apparatus for moving the tissue or other material holder from one receptacle into another is accomplished by a vertical upward movement of the main shaft, to raise the holder above the top of the receptacle in which the holder was positioned, a turning movement of said shaft, for positioning the holder over the receptacle in which the holder is to be next positioned, and a downward vertical movement of the shaft for lowering the holder into said last mentioned receptacle where said holder remains until the next operating cycle which is initiated under the control of a timing device. In accordance with the present invention, provision is made for operating the apparatus to raise and lower the holder without an intervening turning movement of the main shaft when, as is sometimes the case, such turning movement is not desired.
Also in accordance with the present invention, provision is made for preventing damage to the apparatus in case of excessive resistance to the downward movement of the main vertical shaft in section,
.embodying'the present invention, showing the which might possibly be encountered, for example, when the tissue holder is being immersed in the paraffin bath at a time when the paraflln is not sufliciently liquefied, or, for example, in case the tissue holder is, accidentally out of alignment with the open top of any receptacle during the downward movement of said shaft.
Further, in accordance with the present invention, provision is made for operating the apparatus independently of the timing device when, as is sometimes the case, it is necessary or desirable to have the apparatus operate before the time predetermined by the setting of the device.
The above and other objects, features and-advantages of the present invention will be more fully understood from the following description. reference being bad to the accompanying drawings.
In the drawings:
Fig. 1 is a view, partly in elevation and partly of an. automatic immersion apparatus position ofge parts when the tissue holder is immersed in ne of the liquid receptacles;
Fig. 2 is a view similar to Fig. 1 showing the position of the parts in which the tissue holder is raised above the receptacle to permit transfer thereof to another liquid receptacle or to obtain access to the holder;
Fig. 3 is a sectional view, on a larger scale, of the device for supporting and rotating the tissue holder;
Fig. 4 is a detail sectional view on the line 4-4 of Fi 3;
Fig. 5 is a sectional view on the line 55 of Fig. 1'; I
Fig. 6 is a front view of the apparatus;
Fig. 7 is a circuit diagram;
Fig. 8 is a top view of the apparatus;
Fig. 9 is a view taken along the line 9-9 of Fig. 1,-one of the movable parts being in a different position for clearness of illustration;
Fig. 10 is a top plan view, partly in section, on the line Ill-l0 of Fig. 1;
Fig. 11 is a sectional view on the line H-ll of Fi 10;
Fig. 12 isa detail sectional lZ-l2 ofFig. 11;
Fig. 13 is a sectional view on a larger scale of parts of the mechanism illustrated in Flg. 11;
Fig. 14 is a view similar to Fig. 13 showing a modification; I r
Fig. 15 is a front view of the timing device;
Fig. 16 is a rear view thereof;
Fig. 17 is a sectional view on the line ll-i'l of Fig. 15 but shows the cam of the timing disk in a different position; I
Fig. 18 is a front view .of part of the timing device illustrated in Fig. 15, showing the position view on the line of certain of the parts, when the device is operated independently of the notches in.the timing disk;
Fig. 18A is an enlarged detail sectional view on the line I8a-l6a of Fig. 15.
Referring now to the drawings in detail, the automatic immersion apparatus embodying the present invention comprises, as disclosed in my above mentioned patent, a cabinet I6 on which a receptacle table or support 12 is mounted for supporting a plurality of receptacles I4 for the various liquids in which the tissue or other material subjected to treatment thereby is immersed. Said receptacles are removably positioned in the trays I5 which are fixed to table I2. A illustrated in Fig. 8. said receptacles are arranged in a circle on support I2. ,A vertical shaft I6 is mounted at the center of said circle for longitudinal and rotary movement and has fixed thereto near its upper end a frame I6 which is raised and lowered by the vertical upward and downward movements, respectively, of said shaft, and which is turned with said shaft duringthe rotation thereof. Said frame comprises a circular plate or disk 26 to which is secured a plurality of arms 22 which are circumferentially spaced and extend radially from the center of the circle. The inner ends of said arms are fitted in companion grooves 24 in which they are secured in any suitable way as by screws 26. The outer ends of arms 22 extend to positions in which they lie over the receptacles I4, and the outer end of each of said arms is provided with a slot 28 which terminates at its inner end in an enlarged circular part 36, as illustrated in Fig. .8, from which the head 32 of one of the receptaclecover supporting rods 34 has been omitted in order to illustrate the shape of said slot. (See also Fig. 4.) As shown in the drawings, the rods 34 which carry the receptacle covers 36 are provided with reduced portions 36 to permit the attachment and removal of said rods 34 to and from the companion arms 22, substantially as described in my above mentioned patent.
The mechanism for operating shaft I6 for moving the same vertically and for turning the same between the upward and. downward movements in said shaft is operated by the electric motor M (Fig. The rotary shaft of said motor is provided with a worm gear 46 which meshes with a worm wheel 42 fixed to a shaft 44 which is jour- 5 nailed for rotation in bearings 46 and 46 (Fig. 9). A worm gear 50 is fixed to shaft 42 and meshes with a worm wheel 52 fixed to a shaft 54 journalled for rotation in a frame 56 mounted on the base 56 of the cabinet. A link 66 is pivotally connected at its opposite ends to worm wheel 52 and to a cross head 62. Said cross head 62has a circular tubular opening 64 in which the lower circular portion I6aof shaft I6 is slidably and rotatably movable. Said lower portion l6a of shaft I6 is of reduced diameter providing said shaft with a shoulder 6-6 (Fig. 11) which is engaged by the upper edge of cross head 62. It will be understood that when cross head 62 is moved upwardly by link 66, shoulder 66 of shaft I6 is engaged by the upper end of cross head 62 and the shaft is thereby raised as is also operated cross head 62, being movable downwardly independently of said shaft, exerts no downward pull thereon. It will be understood that by reason of this relation between shaft I6 and the power operated cross head 62, the possibility of damage to various part of the apparatus is eliminated or substantially reduced in the event that the normal downward move ment of shaft I6 is opposed. Cross head 62 is provided with rollers 68 which engage a guide bar 16 fixed in the standard 12, said rollers 68 and bar 10 constituting means for guiding cross head 62 in its vertical up and down movements. A compression spring 1| is provided to ease the shock in the event that shaft I6 is suspended above cross head 62 out of supporting relation therewith.
Shaft I6 is rotated intermittently by a Geneva gear mechanism as explained in my above mentioned patent. Said Geneva gear mechanism comprises a gear 14 which surrounds shaft l6 and through which said shaft is longitudinally movable. Gear 14 is rotated by a cooperating Geneva gear member 16 which is actuated by the vertical shaft 16 from shaft 54 through the companion bevel gears 66 and 62. This Geneva gear mechanism i of the same construction and operates in the same way as the Geneva gear mechanism illustrated and described in my above mentioned patent, but in the present construction provision is made for preventing rotation of shaft I6 during any cycle of operation of the apparatus, as may be desired. For this purpose, the pin 64 which is fixed to and is operated by the cooperating Geneva gear member 16 and which normally engages in the slots 66 of gear 14 for imparting a partial rotation thereto between the raising and lowering of the shaft, is retractable to prevent its engagement in said slots when a turning movement of shaft I6 is not desired. For this purpose, pin 84 is mounted for movement in a bracket 88 which is fixed to the bar rotated by gear 16 (Fig. 13). Pin 64 is held in normal position by a spring 62 for engagement with slots 66 during the rotation of gear 16 for rotating gear 14, and is movable to a retracted position in which said pin is located above the upper surface of gear 14 so that it is incapable of engaging in the slots 66 of said gear. Pin 64 is provided with a cross pin 64 which engages the top of bracket 66 when the pin is moved to its retracted position and given a partial turn to bring said cross pin ,64 out of registry with the slot 66 provided in bracket 66 (Fig. 11). Thus, when it is desired to prevent rotation of shaft I6, pin 84 is moved upwardly to a point above the upper edge of bracket 66,
cross pin 64 moving out of slot 66, and pin 64 the frame l6 which is carried thereby. On the I other hand. when cross head 62 is moved downwardly by link 66, shaft I 6, said frame I8 and the parts carried by said frame and by said shaft move downwardly by gravity, without any downward pull on said shaft by cross head 62. Accordinglyin the event of excessive resistance to the downward movement of shaft I6, the power is turned so that it is supported by the upper edge of said bracket, and when it is desired to restore the rotary operation of shaft I6, said pin 84 is turned so that its cross pin 64 registers with slot 66 whereupon spring 62 moves pin 84 downwardly to its normal projected position for engagement with slots 66 during the rotation of gear 16.
Provision is made for rotating the tissueor other material holder 66 (Figs. 1 and 2) in the various liquid receptacles I4. The means for ac-,
complishing this result pursuant to the present invention will now be described. As illustrated in Figs. 1 and 2, the holder 66 is carried by the supporting and rotating device indicated generally by the numeral I06 in Figs. 1, 2 and 3. Said device is mounted on and is movable with frame It being it is rotatable independently of said plate.
movably fits when the-bracket is mounted thereon. Said bracketisalso provided with a tubular opening I06 in jwhich a pin I08 of circular cross section is longitudinally and rotatably movable. 'Ifheupper end of pin I08 is provided with adjustable nuts H and H2, nut IIO engaging the upper edge 4 of bracket I02 when pin I08 is in its normal position. The lower end of pin I08 is provided with a reduced portion I I6 which is small enough to pass through the narrow part of slot 28. to permit bracket I02 to be mounted on and removed from the companion carrying arm 22. It will be understood that the part of the pin I08 above the said reduced portion II6 thereof is too large to pass through slot 28 but fits in the inner larger end portion of said slot and thus releasably holds bracket I02 against movement longitudinally of arm 22. It will be I understood that when it is desired to remove bracket I02 from arm 22, pin I08 is raised to the position illustrated in Fig. 3 in which pin portion H6 is in alignment with slot 28, so that bracket I02 can be moved outwardly of arm 22. Conversely, when it is desired to assemble bracket I02 on'any one of the arms 22, pin I08 is raised to align portion II6 thereof with slot 28, thus allowing the bracket to be moved longitudinally inwardly of the outer end of arm 22 to a position in which the pin engages the inner end of the slot, after which pin I08 is lowered in the larger part 30 of slot 28 for holding the bracket releasably in correct position onarm 22 and against movement longitudinally of said arm in either direction.
A motor-carrier H8 is supported by the lower end of pin I08 being removably secured to said pin by nuts I20 and I22 threaded end of said pin and positioned at opposite sides of the cover I24 of said motor-carrier II.8. Said carrier is in the form of a housing for the electric motor MI and includes in addition to the cover I24 a plate I26 towhich said motor is fixed. Cover I24 is secured to plate I26 in any suitable way as by screws I28 and completely encloses said motor. A vertical shaft I30 is rotated by motor Ml through suitable reduction gearing and extends through plate I26 in whicg bracket I32 is fixed to and rotatable by shaft I30. Said bracket is provided with down turned end portions I34 provided with" apertures I36 in which laterally projecting pins I38 carried by holder 98 are removably engaged. A spring member I40 is fixed to bracket I32 and imparts sufficient resiliency to said bracket to allow end portions I34 thereof to be sprung over pins I38 and to permit the disengagement of said pins from the apertures I36 of the bracket for connecting and disconnecting holder98 to and from bracket I32.
Provision is made in the apparatus for controlling the operation of motor MI which rotates the holder 88 in the various receptacles. I4, and more particularly to operate said motor only when the holder 98 is positioned in the liquid receptacle pursuant to a predetermined downward movement of shaft I6 ried thereby. For this purpose motor MI is connected to an electric outlet device I42 which is supplied with current through a switching and control device I44. The outlet device I42 on the lower is in fixed relation to shaft I6. Preferably, as here shown, outlet device I42 is secured to the hub portion I46 of frame I8 in any suitable way as by set screws I48, said hub portion being secured to shaft I6 by set screws I50. A collar I52 is secured to shaft I6 by said screws I54 below outlet device I42 for limiting thedownward movement of frame I8 on said shaft I8 and thereby assisting in the positioning of said frame on;
said shaft and of the outlet device I42, and assisting screws I50 in holding frame I8 against and frame I8 carmovement downwardly of said shaft. Outlet device I42 is provided with a pair of relatively insulated continuous metal rings I56 and I58 which are electrically connected in parallel to a plurality of outlet sockets I60. An electric plug I62 at the end of an electric cord I64-connected to motor MI is receivable in any one of said sockets for connecting said motor to a source of power when the outlet device is energized through device I44 as will'now be described. The switching and control device I44 is mounted in fixed position below the outlet device I42. More particularly, said device I44 comprises a horizontal plate I66 which fits over and is fixed to the stationary guide bearing I68 in which shaft I6 is movable.' Said part I66 of device I44 has an integral collar I10 which is fixed to shaft guide I68 in any suitable way, as by one or more set screws I12. A pair of spring projected metal pins I14 and I16 are carried by'plate I66 in position to engage conductor rings I56 and I58 of outlet device I42 when shaft I6 is moved downwardly and is near the end of its downward travel, and a switch I18 is carried by plate I66 in position to be operated by the bottom of outlet I42 when shaft I6 is at the end of its downward travel. Said switch is a normally open switch and as here shown is provided with a pin I80, which is moved downwardly against the action of a spring (not shown) contained in said switch. It will be'understood that contact pins I14 and I16 are in series with the contacts of switch I18 so that an electric potential is applied to said contact pins I14 and I16 when switch I18 is closed. Further it will be understood that when contact rings I56 and I56 engage pins I14 and I16, respectively, and switch I18 is closed, which is the condition illustrated in Fig. 1 of the drawings, current is supplied to the outlet device I42 for application to motor MI for rotating the holder 98. Accordingly, when shaft I6 is lowered for positioning holder 68 in a receptacle I4, said holder is thereupon rotated in said receptacle until shaft I6 is raised preliminary to transferring the holder 88 from said last mentioned receptacle into another receptacle I4. It will be understood that just before shaft I6 reaches its lowermost position, conductor rings I56 and I58 engage the companion contact pins I14 and I16 and that upon a further downward movement of said shaft the switch actuating pin I is engaged by the bottom of outlet device I42 for closing said switch. It will be understood that pins I14 and I16 are engaged before switch I18 is closed and are disengaged after switch I18 is opened, thus eliminating sparking at the contacts between the conductor rings I56, I58 and the com;- panion contact pins I14, I16. It will be noted that while as shown the apparatus is provided with only one holder rotating and supporting device I00, there is provision for utilizing additional holder rotating and supporting devices so that if desired a plurality of holders may be simultaneously positioned in different receptacles, respecbe noted, that when the carrier H8 is moved downwardly pursuant to the downward movement of frame I8 by shaft I6, the lower surface of plate I26 may engage the top edge of the companion receptacle, and this can occur before the downward movement of shaft I6 is completed, since motor-carrier II 8 is supported by the pin I08 which is slidable in bracket I02.
The apparatus is operated under the control of a timing device I82 having a notched control disk I84, as described in my 'above mentioned Letters Patent. Said timing device I82 is positioned within cabinet I (Figs. 6 and 10) and the cabinet is provided with a hinged door I86 having a transparent window I88 through which timing disk I84 and other parts of the timing device are visible. The circuit of motor M is completed and interrupted at the proper times by the timing devices I82 substantially in the same way as described in my above mentioned patent, except that in lieu of the mercury switches disclosed in said patent there are utilized in the present apparatus double-throw micro-switches I 90 and I92, switch I90 being operated by the timer I82 and switch I92 being operated bya cam I94 rotated by shaft 54. The timing disk I84 is provided with peripherally spaced notches I96 separated by continuous peripheral or circumferential edge portions of the disk. Said timer disk is removably secured to a plate I98 which is rotated by the shaft of an electric clock-motor 200.
A lever 202 is secured to a spindle 204 which is mounted for turning movement in a bearing 206 in the frame 208 of the timing device. Said lever has a part 2I0 which engages the peripheral edge of timing disk I84 and which is movable successively into notches I96 during the rotation of said timing disk of clock-motor 200. An arm H2 is fixed to spindle 204 (Figs. 16 and 17) and is engaged by the slidable operating pin 2I4 of the micro-switch I90, said switch I90 having the usual spring which resiliently presses pin 2I4 outwardly in engagement with arm 2 I2, and thus biases lever 202 in a direction to resiliently hold part 2I0 in engagement with the peripheral edge of disk I84 and to bias said part 2I0 for movement into notches I96, when the latter are in alignment with the adjacent end of part 2I0. An arm 2I6 is mounted for turning movement on a fixed pivot pin 2| 8 and has fixed thereto a weighted arm 220, the weight being indicated at 222, which tends to turn arm 2I6 in a clockwise direction viewing Fig. 15. Said arm H6 is provided with a notch 224, in which a pin 226 carried by lever 202 is engaged for limiting the pivotal movement of lever 202 in a counter-clockwise direction. Said arm M6 is also provided with a notch 228 in which pin 226 is engaged when lever 202 is moved to its retracted position by the cam 230 at the end of one rotation of cam disk I84, that is at the completion of the operation of the apparatus as described in my above mentioned patent.
It is sometimes necessary or desirable to operate motor M for raising shaft I6 before part 2I0 of lever 202 is in a position to move into a notch I96. Provision is made in the apparatus of the present invention for accomplishing this result. For this purpose part 2I0 of lever 202 is pivotally connected to the adjacent end of the main part 232 of said lever by a pivot pin 234. As illustrated in Fig. 18A, part 2I0 has a recessed portion 236 in which the adjacent end of part 232 is pivotally connected by said pin 234.. A spring 238 fixed to part 232 bears on part 2I0 for holding the latter in normal position. When it is desired to actuate motor M for raising shaft I6 before part 2I0 engages the timing disk I84 in a notch thereof, lever 202 is turned counterclockwise, part 2I0 being pivoted downwardly against spring 238 allowing lever 202 to move in a counter-clockwise direction by the amount necessary to permit the operation of micro-switch I90, this operation being the equivalent of the operation of said switch I when part 202 engages in a notch I 96 in the timing disk. Thus the apparatus can be operated, if desired, before a notch of the disk is aligned with part 2| 0 of lever 202. Further, it will be understood that when it is desired to raise the shaft I6 before part 2I0 engages in a notch I96, it may be desired to prevent rotation of shaft I6 which normally occurs after the shaft is raised to lift the holder 98 out of the receptacle I4 in which it is positioned, since in the normal operation of the apparatus the holder 98 after being raised out of the receptacle is moved laterally of that receptacle to a position over another receptacle into which the holder is lowered by the subsequent downward movement of shaft I6. Accordingly, it will be understood that whenshaft I6 is raised, pursuant to the movement of part 2I0 of lever 202 to the position illustrated in Fig. 18 for raising said shaft before said part engages in a notch I96 of the timing disk and a turning movement of said shaft is not desired, the pin 84 of the Geneva gear mechanism will be moved to its retracted position so that shaft I8, although rotated by gear wheel 52 when motor M is actuated, would be ineffective to actuate the Geneva gear mechanism for turning shaft I6.
When the motor M is set into operation by the movement of lever part 2I0 to the position illustrated in Fig. 18, the cycle of operations is the same as that which occurs when said part engages the disk in a notch I96 thereof. Thus, referring to the circuit diagram illustrated in Fig. 7, it will be noted that in the normal operation of the apparatus, when lever part 2I0 is in engagement in the normal position thereof with the peripheral edge of timing disk I84, the circuit through motor M is interrupted by reason of the fact that the movable contact member 240 of micro-switch I90 and the movable contact member 242 of the cam actuated switch I92 are in the positions illustrated in full lines in Fig. 7. When movablecontact member 240 is moved from its stationary contact member 244 to its other stationary contact member 246, that is to its dotted line position, a circuit is completed through said movable contact member 240, the stationary contact member 246, from the latter over the wire connection 248 to the stationary contact member 250 of switch I92, which is then engaged by the movable contact member 242 of switch I92, it being understood that the dotted line position of movable contact member 240 of switch I90 illustrates the position thereof when part 2I0 of lever 202 engages disk I84 in a notch I96. As soon as movable contact member 246 of switch I60 is in the dotted line position illustrated in Fig. 'l and a circuit is completed through motor M, gear wheel 52 is rotated, thereby actuating link 60 for raising shaft l6 and actuating shaft 64 for rotating the shaft "which actuates the Geneva gear for turning shaft l6. It will be understood that the Geneva gear by reason of its construction and operation is effective to turn shaft l6 only after said shaft has raised holder 98 out of the receptacle, and that as soon as this occurs said Geneva gear operates to turn said shaft for moving holder 98 laterally to a position over the next receptacle, after which.
tact member engages the companion stationary contact member 252 which is connected by the wire 254 of the stationary contact member 246 of switch I90. Accordingly, the circuit through motor M is maintained and shaft 54 which operates cam I94 continues to rotate untilpart 2! of lever 202 is moved out of the notch of the timing disk, and by this time cam I94 has disengaged the micro-switch I92 so that the latter is moved automatically by its spring action from the dotted line position illustrated in Fig. 7, to the full line position thereof, thus interrupting the circuit through the motor at which time the parts are positioned for the next operating cycle of the apparatus. The same operation takes place when, instead of part 2N of lever 202 moving into a notch I96 of the timing disk, said part 2l0 is moved to the position illustrated in Fig. 18, which as heretofore stated is the equivalent of the movement of said part 2"! into a notch of the disk.
In Fig. 14 of the drawings, there is illustrated a different form of device for rendering the Geneva gear mechanism inoperative for turning shaft I6. In the construction illustrated in Fig. 14, provision is made for moving the Geneva gear 16 and the pin 84a which normally engages the main Geneva gear 14 to positions in which said- 262 so that by moving said lever downwardly to the dotted line position illustrated in Fig. 14, coupling member 260 is disengaged from coupling member 256, and gear 56 and the slot-engaging pin 84a are moved out of operative relation to gear I4. Any suitable means may be provided for releasably holding lever 264 in its dotted line position to which it has moved for rendering the Geneva gear mechanism inoperative to turn shaft l6. For example, as here shown, this means may comprise a projection 210 on arm 266 which engages over the upper edge 212 of lever 264 when said lever is depressed, there being sufficient play between the parts to permit the disengagement of projection 210 from lever 264 when it is desired to restore the mechanism to its normal condition.
/ Provision is made for optionally interrupting the operation of the timing device when the shaft I6 is operated, so that the timing disk is not rotated at the times when the holder is being transferred from one of the receptacles l4 to another. This interruption of the timing device may be desirable when the clock-motor is a one-hour or other short period clock, so that the disk makes one revolution in a comparatively short period and the time consumed inv moving the holder from one receptacle to another is large in comparison to the time of one revolution of the timing disk. Accordingly, a normally closed switch 256 (Fig. 1) is provided in the circuit of clock-motor 200, and is held closed by a cam 258 operated by shaft 54. As soon as gear 16 and the pin 84a are out of cooperative relation with the Geneva gear 14. For this purpose, shaft 18a which corresponds to the shaft 18 described above is provided with a coupling member or socket 256 having a square or other non-circular recess 256 in which the coupling member 260 of shaft 262 is releasably engageable, said coupling member 260 being preferably of the same cross sectional configuration as the recess 258 of coupling 256 and being slidable into and out of said recess. The upper end of shaft 262 is fixed to the gear 16, and when coupling member 260-15 engaged with coupling member 256 operated by shaft 18a, shaft 2621s rotatable by shaft 18w for operating the Geneva. gear mechanism in the normal way. In the event, however, that it is desired to render the Geneva gear mechanism ineffective to turn shaft l6, shaft 262 is raised for disconnecting coupling 260 from coupling 256 and for moving gear 16 and the slot-engaging pin 84a to positions above Geneva gear I4. For this purpose, a lever 264 is pivotally mounted on an arm 266 fixed to coupling 255 and engages under a collar 266 fixed to shaft shaft 54 begins to rotate, at the start of the cycle in which shaft I6 is actuated, said cam disengages said switch 256 and the latter opens thereby interrupting the circuit of clock-motor 200, and at the completion of one rotation of shaft 54, i. e., at the end of the'cycle of operation of shaft l6, cam 258 engages switch 256 and closes the same, thus completing the circuit through motor 200 for operating the timing device. Preferably a by-passing switch 260 is provided in the circuit of motor 200 (see Fig. 7). This switch is normally open so that motor 200 is controlled by switch 256, but when it is desired to eliminate the control of switch 256, switch 260 is closed and the timing device is in that case operated continuously.
While I have shown and described the preferred embodiment of my invention, it will be understood that the latter may be embodied otherwise than as herein specifically disclosed. and that in the illustrated embodiment certain changes in the details of construction and in the arrangement of parts may be made without departing from the invention. Accordingly, I do not wish to be limited to the construction herein illustrated or described except to the extent which may be required by the scope of the appended claims.
Having thus described my invention, what I claim and desire to secure by Letters Patent is:
In apparatus of the class described comprising a plurality of receptacles, a holder movable into and out of said receptacle, and means for effecting relative vertical and lateral movements of said holder and receptacle for conveying said holder out of one of said receptacles and into another of said receptacles; means for rotating said holder in one of said receptacles when the holder is positioned therein comprising a carrier mounted for movement laterally of said receptacles and toward and away from said receptacles in vertical line therewith, respectively. a motor mounted on said carrier and movable therewith to positions over and in line with said receptacles, a vertical shaft mounted for rotation in said carrier and connected to said motor for rotation thereby, and means for connecting said holder to said shaft for rotation thereby.
2. In apparatus of the class described comprising a plurality of receptacles, a holder movable into and out of said receptacles, and means for effecting relative vertical and lateral movements of said holder and receptacle for conveying said holder out of one of said receptacles and into another of said receptacles, means for rotating said holder in one of said receptacles when the holder is positioned therein comprising a carrier mounted for movement laterally of said receptacles and toward and away from said receptacles in vertical line therewith, respectively, a motor mounted on said carrier and movable therewith to positions over and in line with said receptacles, a vertical shaft'mounted for rotation in said carrier and connected to said motor for rotation thereby, and means for connecting said holder to said shaft for rotation thereby, said carrier comprising a plate adapted to seat upon and cover the receptacle in which said holder is positioned. I
3. In apparatus of the class described comprising a plurality of receptacles arranged in a circle, a shaft disposed vertically at the center of said circle and mounted for rotation and for vertical movement, a member extending radially from said shaft above said receptacles and movable by said shaft toward and away from said receptacles and laterally thereof, and a holder movable under the control of said member into and out of said receptacles; means for rotating said holder when the latter is positioned in one of said receptacles comprising a carrier mounted on said member and movable therewith to positions over said receptacles, respectively, in vertical alignment therewith, a motor supported on said carrier, a vertical shaft mounted for rotation in said carrier and rotatable by said motor, and means for connecting said holder to said last mentioned shaft for rotation thereby when said holder is positioned in one of said receptacles.
4. In apparatus of the class described compris ng aplurality of receptacles arranged in a circle, a shaft disposed vertically at the center of said circle and mounted for rotation and for vertical movement, a member extending radially 5 from said shaft above said receptacles and movable by said shaft toward and away from said receptacles and laterally thereof, and a holder movable under the controlof said member into cal alignment therewith, a motor supported on said carrier, a vertical-shaft mounted for rotation in said carrier and rotatable by said motor, and means for connecting said holder to said last mentioned shaft for rotation thereby when said holder is positioned in one of said recep- 7 tacles, said carrier comprising a plate adapted to cover the receptacle in which said holder is positioned.
5. In apparatus of the class described compriscle, a shaft disposed vertically at the center of said circle and mounted for rotation and for vertical movement, a member extending radially from said shaft above said receptacles and movable by said shaft toward and away from said,
receptacles and laterally thereof, and a holder movable under the control of said member into and out of said receptacles; means for rotating said holder when the latter is positioned in one of said receptacles comprising a carrier mounted on said member and movable therewith to positions over said receptacles, in vertical align ment therewith, respectively, a motor supported on said carrier, a vertical shaft mounted for rotation in said carrier and rotatable by said motor, and means for connecting said holder to said last mentioned shaft for rotation thereby when said holder is positioned in one of said recepta-,
ing' an open-top receptacle, a holder mounted.
for movement into and out of said receptacle through said open-top thereof, said holder being also mounted for rotation in said receptacle; means for rotating said holder and for supporting the same, comprising a bracket, a frame supported by said bracket, a motor carried by said,
frame, a shaft mounted for rotation in said frame and rotatable by said motor, and means for connecting said holder to said shaft for rotation thereby.
7. In apparatus of the class described comprising an open-top receptacle, a holder mounted for movement into and out of said receptacle through said open-top thereof, said holder being also mounted for rotation in said receptacle; means for rotating said holder and for supporting the same comprising a horizontal arm mounted for vertical movement, a bracket removably supported by said arm, a frame supported by said bracket, 9. motor carried by said frame, a shaft mounted for rotation in said frame and rotatable by said motor, and means for connecting said holder to said shaft for rotation thereby.
8. In apparatus of the class described comprising an open-top receptacle, a holder mounted for movement into and out of said receptacle through said open-top thereof, said holder being also mounted for rotation in said receptacle; means for rotating said holder and for supporting the same comprising a horizontal arm mounted for vertical movement, a bracket removably supported by said arm, a frame supported by said bracket, a motor carried by said frame, a shaft mounted for rotation in said frame and rotatable by said motor, and means for connecting said holder to said shaft for rotation thereby, said arm having a slotted part, said bracket having an opening in which the slotted part of the arm fits, said bracket having another opening extending at right angles to said first mentioned opening, a member carried by said bracket and having a limited movement in said other opening, said member having a part ing a plurality of receptacles arranged in a cirit which is narrow eno gh t pa t r h sa n rrow part of said slot and a wider part which cannot pass through said narrow part of said slot, but which can project through said wider part of said slot, said member being movable in said other opening of the bracket to one position in which said narrow part of the member is in line with said narrow part of the slot for movement therein and to a position out of line with said narrow part of the slot.
9. In apparatus of the class described comprising an open-top receptacle, and a holder mounted for movement into and out of said receptacle through said open-top thereof, said holder being also mounted for rotation in said receptacle; means for rotating said holder and for supporting the same comprising a horizontal arm mounted for vertical movement, a bracket removably supported by said arm, a plate carried by said bracket and adapted to engage at one side thereof the top of the receptacle when said holder is positioned therein, -a motor positioned at the other side of said plate, a shaft operated by said motor extending throughisaid plate to said first mentioned side thereof, and means at said first mentioned side of said plate for connecting said holder to said shaft for rotation thereby.
'10. In apparatus of the class described, the sub-combination comprising an arm having,a slot in its end, said slot having a narrow part extending inwardly from the end of said arm to a wider part at the inner end of the slot, a bracket supported by said arm and having an opening in which the slotted part of the arm fits, said bracket having another opening extending at right angles to said first mentioned opening, a member carried by said bracket and having a limited movement in said other opening, said member having a part which is narrow enough to pass through said narrow part of said slot and a wider part which cannot pass through said narrow part of said slot but which can project through said wider part of said slot, said member being movable in said other opening of the bracket to one position in which said narrow part of the member is in line with said narrow part of the slot for movement therein and to a position out of line with said narrow part of the slot, said bracket being removable from said arm in said first position of said member and held against removal from said arm in the second position of said member.
11. In an automatic immersion apparatus, a shaft mounted for rotation and for vertical movement, means for rotating said shaft, and means for raising said shaft, said last mentioned means including a part with respect to which said shaft is longitudinally movable and which in a predetermined relative position of said shaft and said part is engageable with said shaft for raising the same, said part being movable upwardly for raising said shaft and movable downwardly longitudinally of said shaft in relation thereto whereby said part is prevented from exerting a downward force on said shaft when said part moves downwardly faster than said shaft.
12. In an automatic immersion apparatus, a shaft mounted for rotation and for vertical movement, means for rotating said shaft, and means for raising said shaft, said last mentioned means including a part with respect tov which sad shaft is longitudinally movable and which in a predetermined relative position of said shaft and said part is engageable with said shaft for raising the same, said part being movable upwardly for raising said shaft and movable downwardlylongitudinally of said shaft in relation thereto whereby said part is prevented from exerting a downward force on said shaft when said part moves downwardly faster than said shaft, said shaft being normally supported by said part, and means for resiliently opposing the downward movement of said shaft when said part is moved out of supporting relation thereto.
13. In apparatus of the class described comprising a timing disk having a peripheral edge provided with peripherally spaced edge notches and a switch, operable under the control of said disk; means actuated by said disk for actuating said switch comprising a pivotally mounted member having a part engageable with said disk in said notches and with the peripheral edge portions of the disk between said notches, means biasing said member to hold said part in engagement with said disk, said member having a part to which said disk-engaging part is movably secured for movement relatively to said last mentioned part in directions toward and away from the peripheral edge of the disk, and means biasing said disk-engaging part for movement relatively to said last mentioned part toward the peripheral edge of said disk.
14. In apparatus of the class described comprising a timing disk having a peripheral edge provided with peripherally spaced edge notches and a switch operable under the control of said disk; means actuated by said disk for actuating said switch comprising a pivotally mounted member having a part engageable with said disk in said notches and with the peripheral edge portions of the disk between said notches, means biasing said member to hold said part in engagement with said disk, said member having a part to which said disk-engaging part is pivotally secured for movement relatively'to said last mentioned part in directions toward and away from the peripheral edge of the disk, and spring means biasing said disk-engaging part for movement relatively to said last mentioned part toward the peripheral edge of said disk.
15. In an automatic immersion apparatus having a shaft mounted for rotation and for vertical movement, means for moving said shaft in a vertical direction, and means including a Geneva gear mechanism for intermittently turning said shaft in timed relation to the vertical movement thereof, means for rendering said Geneva gear mechanism inoperative to turn said shaft whereby said shaft is movable vertically but not rotatably, said last mentioned means comprising companion parts of said Geneva gear mechanism mounted for relative vertical movement from positions in which said parts are engageable with each other for turning said shaft to positions in which. said parts are in inoperative relation.
16. In an automatic immersion apparatus having a shaft mounted for rotation and for vertical movement, means for moving said shaft in a vertical direction, means for imparting a rotary movement to said shaft in timed relation to the vertical movement thereof, and means for actuating both of said shaft-moving means, means for rendering said last mentioned means inoperative to actuate said shaft rotating means but without rendering the same inoperative to actuate said first mentioned shaft moving means whereby the shaft is movable vertically without rotation thereof, said means for rendering said actuating means inoperative as aforesaid comprising a rotary member actuated by said actuating means, a companion rotary member normally' in engagement with and rotated by said first mentioned rotary member and movable out of operative engagement therewith, and means for moving said companion rotary member out of operative engagement with said first mentioned rotary member.
17. Apparatus of the class described comprising a plurality of receptacles arranged in a circle, a shaft mounted vertically at the center of said circle for rotation and for vertical movement upwardly and downwardly, a horizontal frame fixed to and movable with said shaft, said frame comprising an arm extending radially from said shaft toward said receptacles, an electric-outlet device carried by said shaft below said frame, said outlet comprising a pair of slip rings and a socket connected thereto, a switching device positioned in fixed position below said outlet device, said switching device comprising a switch which is opened and closed by'upward and downward movements, respectively, of said 5 shaft, said switching device comprising also a pair of conductors electrically connected to said switch and engageable with and disengageable from said slip rings when said shaft moves downwardly and upwardly, respectively, a motor sup- 10 ported by said arm and connected to said socket of the outlet device, and a holder supported by said arm and rotatable by said motor, said holder being movable by said arm out of one receptacle and into another by vertical androtary l5 movements of said shaft and rotatable in the receptacle by said motor when said switching device is closed pursuant to a downward movement of said shaft.
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Cited By (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2482133A (en) * 1948-03-23 1949-09-20 Bert M Sweetser Bonding machine
US2510912A (en) * 1948-08-27 1950-06-06 Schurenberg Otto Automatic watch part cleaning machine
US2522416A (en) * 1947-08-21 1950-09-12 Weiskopf Edwin Carl Holder for microscope slides
US2539802A (en) * 1949-03-15 1951-01-30 Edwin C Weiskopf Material-holder carrier for automatic immersion apparatus
US2559921A (en) * 1943-03-20 1951-07-10 Hyman Landaw Automatic machine for sequentially immersing machine parts in successive cleaning liquids
US2583379A (en) * 1949-03-16 1952-01-22 Technicon Company Automatic immersion apparatus
US2619975A (en) * 1949-02-10 1952-12-02 Yardley Chittick C Machine for washing watch parts
US2645236A (en) * 1947-11-10 1953-07-14 Franklin C Fisher Machine for washing watch parts
US2672843A (en) * 1950-08-07 1954-03-23 Mcclean Thomas Sherman Rotary coating and drying apparatus
US2678052A (en) * 1948-10-12 1954-05-11 E & J Swigart Company Watch and like parts washing machine
US2679824A (en) * 1951-07-19 1954-06-01 Western Electric Co Article coating apparatus
US2708635A (en) * 1951-07-12 1955-05-17 Donald R Draper Method of processing meat products
US2721563A (en) * 1953-06-22 1955-10-25 Franklin C Fisher Machine for washing watch parts
US2784724A (en) * 1957-03-12 fisher
US2804840A (en) * 1954-07-01 1957-09-03 Patrick T Dolan Automatic immersion apparatus
US2810366A (en) * 1954-04-14 1957-10-22 Technicon Int Ltd Receptacle carrier for tissue processing
US2845045A (en) * 1954-12-08 1958-07-29 Technicon International Ltd Apparatus for processing histologic tissue and other materials
US2845044A (en) * 1954-06-25 1958-07-29 Technicon Int Ltd Automatic immersion apparatus
DE1038795B (en) * 1953-06-01 1958-09-11 Technicon International Ltd Automatic immersion device, especially for the treatment of histological tissue
US2869508A (en) * 1955-05-09 1959-01-20 Technicon Int Ltd Automatic immersion apparatus
US2869509A (en) * 1955-09-14 1959-01-20 Technicon Int Ltd Automatic immersion apparatus
US2872893A (en) * 1954-12-09 1959-02-10 Technicon Int Ltd Automatic immersion apparatus
US2872894A (en) * 1954-12-09 1959-02-10 Technicon International Ltd Automatic immersion apparatus
US2925820A (en) * 1957-10-03 1960-02-23 Technicon International Ltd Automatic liquid supply for immersion apparatus
US2960962A (en) * 1958-03-03 1960-11-22 Technicon Company Inc Manual control for automatic immersion apparatus
DE1097164B (en) * 1958-06-26 1961-01-12 Technicon Internat Ltd Device for the preparation of histological tissue
US2986114A (en) * 1957-04-01 1961-05-30 Western Electric Co Apparatus for tinning terminals of electrical components
US3110627A (en) * 1959-12-23 1963-11-12 Technicon Company Inc Automatic immersion apparatus
US3227130A (en) * 1962-02-01 1966-01-04 Technicon Company Inc Immersion apparatus for histologic tissue
US3397557A (en) * 1965-12-17 1968-08-20 Thies B Textile processing machine
DE1567188B1 (en) * 1963-07-12 1971-08-12 Technicon Instr Method and device for preparing histological tissue for microscopic examinations
US3809008A (en) * 1972-11-10 1974-05-07 Sakura Finetechnical Co Ltd Apparatus for processing tissue for electron microscope examination
US5098749A (en) * 1990-05-04 1992-03-24 Illinois Tool Works Inc. Workpiece-treating system and related method
US6780380B2 (en) 2001-01-16 2004-08-24 Triangle Biomedical Sciences, Inc. Tissue processor

Cited By (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2784724A (en) * 1957-03-12 fisher
US2559921A (en) * 1943-03-20 1951-07-10 Hyman Landaw Automatic machine for sequentially immersing machine parts in successive cleaning liquids
US2522416A (en) * 1947-08-21 1950-09-12 Weiskopf Edwin Carl Holder for microscope slides
US2645236A (en) * 1947-11-10 1953-07-14 Franklin C Fisher Machine for washing watch parts
US2482133A (en) * 1948-03-23 1949-09-20 Bert M Sweetser Bonding machine
US2510912A (en) * 1948-08-27 1950-06-06 Schurenberg Otto Automatic watch part cleaning machine
US2678052A (en) * 1948-10-12 1954-05-11 E & J Swigart Company Watch and like parts washing machine
US2619975A (en) * 1949-02-10 1952-12-02 Yardley Chittick C Machine for washing watch parts
US2539802A (en) * 1949-03-15 1951-01-30 Edwin C Weiskopf Material-holder carrier for automatic immersion apparatus
US2583379A (en) * 1949-03-16 1952-01-22 Technicon Company Automatic immersion apparatus
US2672843A (en) * 1950-08-07 1954-03-23 Mcclean Thomas Sherman Rotary coating and drying apparatus
US2708635A (en) * 1951-07-12 1955-05-17 Donald R Draper Method of processing meat products
US2679824A (en) * 1951-07-19 1954-06-01 Western Electric Co Article coating apparatus
DE1038795B (en) * 1953-06-01 1958-09-11 Technicon International Ltd Automatic immersion device, especially for the treatment of histological tissue
US2721563A (en) * 1953-06-22 1955-10-25 Franklin C Fisher Machine for washing watch parts
US2810366A (en) * 1954-04-14 1957-10-22 Technicon Int Ltd Receptacle carrier for tissue processing
US2845044A (en) * 1954-06-25 1958-07-29 Technicon Int Ltd Automatic immersion apparatus
US2804840A (en) * 1954-07-01 1957-09-03 Patrick T Dolan Automatic immersion apparatus
US2845045A (en) * 1954-12-08 1958-07-29 Technicon International Ltd Apparatus for processing histologic tissue and other materials
US2872893A (en) * 1954-12-09 1959-02-10 Technicon Int Ltd Automatic immersion apparatus
US2872894A (en) * 1954-12-09 1959-02-10 Technicon International Ltd Automatic immersion apparatus
US2869508A (en) * 1955-05-09 1959-01-20 Technicon Int Ltd Automatic immersion apparatus
US2869509A (en) * 1955-09-14 1959-01-20 Technicon Int Ltd Automatic immersion apparatus
US2986114A (en) * 1957-04-01 1961-05-30 Western Electric Co Apparatus for tinning terminals of electrical components
US2925820A (en) * 1957-10-03 1960-02-23 Technicon International Ltd Automatic liquid supply for immersion apparatus
US2960962A (en) * 1958-03-03 1960-11-22 Technicon Company Inc Manual control for automatic immersion apparatus
DE1097164B (en) * 1958-06-26 1961-01-12 Technicon Internat Ltd Device for the preparation of histological tissue
US3110627A (en) * 1959-12-23 1963-11-12 Technicon Company Inc Automatic immersion apparatus
US3227130A (en) * 1962-02-01 1966-01-04 Technicon Company Inc Immersion apparatus for histologic tissue
DE1567188B1 (en) * 1963-07-12 1971-08-12 Technicon Instr Method and device for preparing histological tissue for microscopic examinations
US3397557A (en) * 1965-12-17 1968-08-20 Thies B Textile processing machine
US3809008A (en) * 1972-11-10 1974-05-07 Sakura Finetechnical Co Ltd Apparatus for processing tissue for electron microscope examination
US5098749A (en) * 1990-05-04 1992-03-24 Illinois Tool Works Inc. Workpiece-treating system and related method
US6780380B2 (en) 2001-01-16 2004-08-24 Triangle Biomedical Sciences, Inc. Tissue processor

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