US2210098A - Apparatus for venoclysis - Google Patents

Apparatus for venoclysis Download PDF

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Publication number
US2210098A
US2210098A US73862A US7386236A US2210098A US 2210098 A US2210098 A US 2210098A US 73862 A US73862 A US 73862A US 7386236 A US7386236 A US 7386236A US 2210098 A US2210098 A US 2210098A
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container
liquid
inlet
venoclysis
outlet
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Expired - Lifetime
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US73862A
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Edward A Ravenscroft
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Abbott Laboratories
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Abbott Laboratories
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • A61M2005/1623Details of air intake
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/8158With indicator, register, recorder, alarm or inspection means
    • Y10T137/8359Inspection means
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/8593Systems
    • Y10T137/86292System with plural openings, one a gas vent or access opening
    • Y10T137/86324Tank with gas vent and inlet or outlet
    • Y10T137/86332Vent and inlet or outlet in unitary mounting

Definitions

  • the present invention relates to apparatus for the intravenous injection of sterile liquids. More particularly the present invention relates tobulk containers for sterile intravenous liquids and ineludes an improved dispensing cap for withdraw ing liquids and admitting sterile air when the container is in an inverted position.
  • the apparatus for venoclysis heretofore available has been found unsatisfactory.
  • one disadvantage found to be prevalent was that the customary air-inlet tube, which extends from the cap or stopper to the bottom of the container is filled with liquid. when the container is inverted the liquid in the air-inlet tube runs out and must be absorbed with towels or caught in a basin in order to prevent-"the soiling of the floor or the patients bed.
  • Another disadvantage was found in that the wetted glass delivery tubes were easily pulled from the rubber stoppers by the weightof the rubber tube extending to the patient. Accidents 'of this type are far more serious than the mere leaking or spilling of the solution.
  • apparatus for venoclysis may be connected with the ,vein in the patients 2!
  • Fig. 1 is a side elevation for a single bulk container arranged for intermittent venoclysis.
  • Fig. 2 is a side elevation of two of my improved, bulk containers arranged in series for continuous venoclysis.
  • Fig. 3 is. an enlarged longitudinal section through my improved dispensing cap and a por-' tion of the container.
  • Fig. 4 is an enlarged side elevation, partly in section, of the upper portion of my container provided with a metal cap and tamper-proof seal.
  • a glass bottle or flask Ill such as is suitable for containing sterile liquids used for intravenous injections, is supported in an inverted position by means of a circular metal band H provided with an adjustable bail orhandle l2, hung on any suitable support such as represented at It.
  • the container may also be provided with gzaduated markings l5 for measuring the liquid
  • the dispensing cap l1 preferably made of molded material, is threaded on the neck of'the container as shown in Fig. 3. a This dispensing cap is provided with an outlet aperture l8 and a separate inlet aperture l9, and integral external nipples l8 and I9 communicating respectively with the apertures. Attached to nipple l8 communicating with outlet aperture I 8, is a conduit 20 leading to a flow indicator 2
  • the conduit which may be made of rubber, is provided with a conventional adjustable pinch clamp 22 which is used to regulate the flow 0 liquid from the container.
  • the nipple I9 is connected by conduit 24 to an external air inlet 25.
  • the air. inlet should be elevated above the level of the liquid in container ill to insure against leakage of liquid.
  • a cotton filter such as indicated at 26 may be used to maintain the sterility of the air entering the container III.
  • the filter may be any open container suitable for holding cotton or like porous material and may be supported in a manner similar to that of the liquid container previously described.
  • a conduit 21 connects (outlet) nipple ll of container III with (inlet) nipple IQ of container ill, the (inlet) nipple I! of container II being connected by means of conduit "to the external air inlet 25 which is elevated above the level of liquid in containers l0 and ill.
  • the outlet aperture of my preferred dispensing cap (Fig. 3) is provided with an enlargement or counter bore 28, the bottom of which is positioned so thatit will. be lower than the inlet aperture when the container is inverted. This arrangement prevents the air, which enters the inlet aperture, from passing with the liquid through the outlet aperture to the injection needle.
  • the container is provided with (Fig. 4) a metal cap 30 and a tamper-proof seal 3
  • the metal cap is provided with a liner 32 which will not contaminate the sterile liquid.
  • the tamper-proof seal and the metal cap are removed and the dispensing cap fitted on the container in the conventional manner.
  • the external air inlet is supported above the liquid in the container at all times not only during the venoclysis itself, but also during the attachment of the cap to the container and the inversion of the con-.
  • a continuous venoclysis apparatus (Fig. 2) carries liquid from container ID to container l0. It will be understood that while I have shown my continuous venoclysis apparatus employing only two of my containers, any multiple thereof arranged in series may be used.
  • the adjustable pinch clamp 23 used on the outlet line 20 to control the flow of liquid from the container may be placed, if desired, on the inlet lines 24 or 28 and used to control the flow of air into the container, which automatically controls the flow of liquid from the container.
  • Air which may or may not be filtered is emitted at 25;.
  • the elevation of the external air inlet prevents leakage of the liquid, the passage of the liquid from the container being at alltimes restricted to the outlet aperture.
  • in Figure 1 and conduit 28 in Figure 2 connecting inlet nipple 19' with air filters 25, are each providedwith a loop which extends downwardly below the level of'the outlet nipple l8.
  • This arrangement prevents the liquid from flowing out or the outlet nipple l8 when the delivery tube 20 becomes accidentally detached therefrom. This action may be explained by the fact that the column of liquid in the loop of the tube conduit creates a slight vacuum which holds the liquid in the container when the outlet conduit becomes detached from the outlet nipple.
  • the nipples extend downwardly when the apparatus is inverted. This arrangement in which the axis of the inlet nipple is substantially perpendicular to the plane of the cap necessitates the downwardly extending loop in the inlet tubes.
  • nipples l8 and I9 should be of equal length, i. e., the ends 01' the nipples should extend downwardly to substantially the same level when the container is inverted. This arrangement not only necessitates a loop in the inlet conduit as indicated in the paragraph above, but in addition insures that the loop will be below the end of the outlet nipple.
  • An apparatus of the character described comprising a container having an opening therein, a dispensing cap positioned over said opening, said dispensingcap having an outlet aperture and a separate inlet aperture therein, the outlet aperture being enlarged at its inner end to form an enlargement and the bottom of said enlargement being so positioned that when the container is inverted the said bottom is lower than the inner end of said inlet aperture, external outlet and inlet nipples of equal length communicating respectively with said outlet and inlet apertures and extending downwardly to the same level when the container is inverted, a conduit for connecting said outlet nipple to an injection needle, a second conduit for connecting said inlet nipple to an external air filter elevated above liquid in the container, said second conduit being/ formed to provide a loop extending below said outlet nipple when the container is in operating position and means for regulating and observing the flow of liquid from the container.

Description

6, 1940- 'E. A. RAVENSCROFT I 0,0 8
APPARATUS FOR VENOCLYSIS Filed April 11, 1956 Patented Aug. 6, 1940 APPARATUS FOR VENOCLYSIS Edward A. Ravenscroft, Glencoe, Ill., assignor to Abbott Laboratories, North Chicago, 111., a corporation oiIllinois Application April 11, 1936, Serial No. 13,862 rciaim. (or. 128-214) The present invention relates to apparatus for the intravenous injection of sterile liquids. More particularly the present invention relates tobulk containers for sterile intravenous liquids and ineludes an improved dispensing cap for withdraw ing liquids and admitting sterile air when the container is in an inverted position.
The apparatus for venoclysis heretofore available has been found unsatisfactory. For example, one disadvantage found to be prevalent was that the customary air-inlet tube, which extends from the cap or stopper to the bottom of the container is filled with liquid. when the container is inverted the liquid in the air-inlet tube runs out and must be absorbed with towels or caught in a basin in order to prevent-"the soiling of the floor or the patients bed. Another disadvantage was found in that the wetted glass delivery tubes were easily pulled from the rubber stoppers by the weightof the rubber tube extending to the patient. Accidents 'of this type are far more serious than the mere leaking or spilling of the solution. For example, apparatus for venoclysis may be connected with the ,vein in the patients 2!! arm for hours at a time and if the glass delivery tube is pulled from the rubber stopper, the flow of the solution into the vein stops immediately. While I do not know that patients have been bled by such accidents, it is quite possible that the rubher tube extending from the needle in the'vein of the patient to the glass tube in the stopper would fall to a level lower than the patients bed and cause a serious loss of blood before the accident would be discovered. An additional dis- :5 advantage of the containers in common use is the closure with a rubber stopper which on sterilization imparts to the enclosed solution the taste and odor of some constituents of the rubber.
' It is the object of my invention to provide an apparatus for venoclysis free from the disadvantages enumerated above.
Further objects of my invention will be apparent from the following description. I
In the accompanying drawing forming a part of this specification:
Fig. 1 is a side elevation for a single bulk container arranged for intermittent venoclysis.
Fig. 2 is a side elevation of two of my improved, bulk containers arranged in series for continuous venoclysis.
Fig. 3 is. an enlarged longitudinal section through my improved dispensing cap and a por-' tion of the container.
. Fig. 4 is an enlarged side elevation, partly in section, of the upper portion of my container provided with a metal cap and tamper-proof seal.
Referring with more particularity to the drawing, a glass bottle or flask Ill such as is suitable for containing sterile liquids used for intravenous injections, is supported in an inverted position by means of a circular metal band H provided with an adjustable bail orhandle l2, hung on any suitable support such as represented at It. The
band bears against a circumferential bead I4 on the container which bead holds the container in place. The container may also be provided with gzaduated markings l5 for measuring the liquid The dispensing cap l1, preferably made of molded material, is threaded on the neck of'the container as shown in Fig. 3. a This dispensing cap is provided with an outlet aperture l8 and a separate inlet aperture l9, and integral external nipples l8 and I9 communicating respectively with the apertures. Attached to nipple l8 communicating with outlet aperture I 8, is a conduit 20 leading to a flow indicator 2| and needle 22. The conduit, which may be made of rubber, is provided with a conventional adjustable pinch clamp 22 which is used to regulate the flow 0 liquid from the container.
In the intermittent venoclysis apparatus shown in- Fig. 1, the nipple I9 is connected by conduit 24 to an external air inlet 25. The air. inlet should be elevated above the level of the liquid in container ill to insure against leakage of liquid. A cotton filter such as indicated at 26 may be used to maintain the sterility of the air entering the container III. The filter may be any open container suitable for holding cotton or like porous material and may be supported in a manner similar to that of the liquid container previously described.
In the continuous venoclysis apparatus shown in Fig. 2, the arrangement is similar to that shown in Fig. 1 except that a conduit 21 connects (outlet) nipple ll of container III with (inlet) nipple IQ of container ill, the (inlet) nipple I! of container II being connected by means of conduit "to the external air inlet 25 which is elevated above the level of liquid in containers l0 and ill.
When employing my bulk containers in series for continuous venoclysis, the liquid in the-container to which the air-vent is attached will empty itself completely before the air can get into the other container andfallow it to empty. By replacing the former container for a fresh full one, it will be unnecessary to refill or change the container to which the needle is connected and the flow of solution through the needle will be uninterrupted over long periods oftime.
The outlet aperture of my preferred dispensing cap (Fig. 3) is provided with an enlargement or counter bore 28, the bottom of which is positioned so thatit will. be lower than the inlet aperture when the container is inverted. This arrangement prevents the air, which enters the inlet aperture, from passing with the liquid through the outlet aperture to the injection needle.
In order to keep the solutions sterile before use, the container is provided with (Fig. 4) a metal cap 30 and a tamper-proof seal 3|. The metal cap is provided with a liner 32 which will not contaminate the sterile liquid.
In the operation of the container for venoclysis, the tamper-proof seal and the metal cap are removed and the dispensing cap fitted on the container in the conventional manner. The external air inlet is supported above the liquid in the container at all times not only during the venoclysis itself, but also during the attachment of the cap to the container and the inversion of the con-.
tainer. For an intermittent injection, the apparatus is arranged as shown in Fig. 1, and for a continuous venoclysis apparatus (Fig. 2) carries liquid from container ID to container l0. It will be understood that while I have shown my continuous venoclysis apparatus employing only two of my containers, any multiple thereof arranged in series may be used. The adjustable pinch clamp 23 used on the outlet line 20 to control the flow of liquid from the container, may be placed, if desired, on the inlet lines 24 or 28 and used to control the flow of air into the container, which automatically controls the flow of liquid from the container.
Air which may or may not be filtered is emitted at 25;. The elevation of the external air inlet prevents leakage of the liquid, the passage of the liquid from the container being at alltimes restricted to the outlet aperture.
As shown in the drawing, conduit 2| in Figure 1 and conduit 28 in Figure 2 connecting inlet nipple 19' with air filters 25, are each providedwith a loop which extends downwardly below the level of'the outlet nipple l8. This arrangement prevents the liquid from flowing out or the outlet nipple l8 when the delivery tube 20 becomes accidentally detached therefrom. This action may be explained by the fact that the column of liquid in the loop of the tube conduit creates a slight vacuum which holds the liquid in the container when the outlet conduit becomes detached from the outlet nipple. As shown in the drawing, the nipples extend downwardly when the apparatus is inverted. This arrangement in which the axis of the inlet nipple is substantially perpendicular to the plane of the cap necessitates the downwardly extending loop in the inlet tubes.
As shown in the drawing nipples l8 and I9 should be of equal length, i. e., the ends 01' the nipples should extend downwardly to substantially the same level when the container is inverted. This arrangement not only necessitates a loop in the inlet conduit as indicated in the paragraph above, but in addition insures that the loop will be below the end of the outlet nipple.
While I have described only the preferred embodiments of my invention, it will be understood by those skilled in the art that the claim appended hereto is intended to cover all modifications coming within the true spirit and scope of my invention.
I claim:
An apparatus of the character described, comprising a container having an opening therein, a dispensing cap positioned over said opening, said dispensingcap having an outlet aperture and a separate inlet aperture therein, the outlet aperture being enlarged at its inner end to form an enlargement and the bottom of said enlargement being so positioned that when the container is inverted the said bottom is lower than the inner end of said inlet aperture, external outlet and inlet nipples of equal length communicating respectively with said outlet and inlet apertures and extending downwardly to the same level when the container is inverted, a conduit for connecting said outlet nipple to an injection needle, a second conduit for connecting said inlet nipple to an external air filter elevated above liquid in the container, said second conduit being/ formed to provide a loop extending below said outlet nipple when the container is in operating position and means for regulating and observing the flow of liquid from the container. EDWARD A. RAVENSCROFI.
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Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2426733A (en) * 1944-09-09 1947-09-02 William R Warner & Co Inc Combination drip stopper
US2452644A (en) * 1946-10-05 1948-11-02 Abbott Lab Apparatus for intravenous administration of liquids
US2923293A (en) * 1955-08-15 1960-02-02 Baxter Laboratories Inc Dispensing closure
US3230954A (en) * 1963-10-08 1966-01-25 Mcgaw Lab Inc Venoclysis equipment and method of administering two different parenteral liquids therefrom
US3756237A (en) * 1971-05-05 1973-09-04 Abbott Lab Irrigation solution administration system and reservoir therefor
US3927671A (en) * 1971-05-05 1975-12-23 Abbott Lab Irrigation solution administration system and reservoir therefor
US3951148A (en) * 1974-05-29 1976-04-20 Pharmachem Corporation Blood component storage bag and glycerolizing set therefor
US4687473A (en) * 1986-02-06 1987-08-18 Burron Medical Inc. Self-contained secondary solution set
US5199947A (en) * 1983-01-24 1993-04-06 Icu Medical, Inc. Method of locking an influent line to a piggyback connector
US5281206A (en) * 1983-01-24 1994-01-25 Icu Medical, Inc. Needle connector with rotatable collar
US5344414A (en) * 1983-01-24 1994-09-06 Icu Medical Inc. Medical connector
US5520640A (en) * 1992-04-30 1996-05-28 Utterberg; David S. Blood air trap chamber
US5688254A (en) * 1983-01-24 1997-11-18 Icu Medical, Inc. Medical connector
US5810792A (en) * 1996-04-03 1998-09-22 Icu Medical, Inc. Locking blunt cannula
US6293304B1 (en) * 2000-11-27 2001-09-25 Du-Bro Products, Inc. Fuel valve
US20040030321A1 (en) * 2000-07-11 2004-02-12 Fangrow Thomas F. Medical valve with positive flow characteristics
US20050197646A1 (en) * 2002-02-11 2005-09-08 Brian Connell Dialysis connector with retention and feedback features
US20060206058A1 (en) * 1991-12-18 2006-09-14 Lopez George A Medical valve and method of use
US20060264910A1 (en) * 2004-11-05 2006-11-23 Fangrow Thomas F Soft-grip medical connector
US20100130919A1 (en) * 2008-11-21 2010-05-27 Baxter International Inc. Systems and methods for removing air from the patient's peritoneal cavity
US8002765B2 (en) 1995-12-15 2011-08-23 Icu Medical, Inc. Medical valve with fluid escape space
USD644731S1 (en) 2010-03-23 2011-09-06 Icu Medical, Inc. Medical connector
US8105314B2 (en) 2006-10-25 2012-01-31 Icu Medical, Inc. Medical connector
US8454579B2 (en) 2009-03-25 2013-06-04 Icu Medical, Inc. Medical connector with automatic valves and volume regulator
US8758306B2 (en) 2010-05-17 2014-06-24 Icu Medical, Inc. Medical connectors and methods of use
USD786427S1 (en) 2014-12-03 2017-05-09 Icu Medical, Inc. Fluid manifold
USD793551S1 (en) 2014-12-03 2017-08-01 Icu Medical, Inc. Fluid manifold
US10369349B2 (en) 2013-12-11 2019-08-06 Icu Medical, Inc. Medical fluid manifold

Cited By (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2426733A (en) * 1944-09-09 1947-09-02 William R Warner & Co Inc Combination drip stopper
US2452644A (en) * 1946-10-05 1948-11-02 Abbott Lab Apparatus for intravenous administration of liquids
US2923293A (en) * 1955-08-15 1960-02-02 Baxter Laboratories Inc Dispensing closure
US3230954A (en) * 1963-10-08 1966-01-25 Mcgaw Lab Inc Venoclysis equipment and method of administering two different parenteral liquids therefrom
US3756237A (en) * 1971-05-05 1973-09-04 Abbott Lab Irrigation solution administration system and reservoir therefor
US3927671A (en) * 1971-05-05 1975-12-23 Abbott Lab Irrigation solution administration system and reservoir therefor
US3951148A (en) * 1974-05-29 1976-04-20 Pharmachem Corporation Blood component storage bag and glycerolizing set therefor
US5688254A (en) * 1983-01-24 1997-11-18 Icu Medical, Inc. Medical connector
US5776116A (en) * 1983-01-24 1998-07-07 Icu Medical, Inc. Medical connector
US5281206A (en) * 1983-01-24 1994-01-25 Icu Medical, Inc. Needle connector with rotatable collar
US5344414A (en) * 1983-01-24 1994-09-06 Icu Medical Inc. Medical connector
US5954708A (en) * 1983-01-24 1999-09-21 Icu Medical, Inc. Medical connector
US5199947A (en) * 1983-01-24 1993-04-06 Icu Medical, Inc. Method of locking an influent line to a piggyback connector
US4687473A (en) * 1986-02-06 1987-08-18 Burron Medical Inc. Self-contained secondary solution set
US7717884B2 (en) 1991-12-18 2010-05-18 Icu Medical, Inc. Medical valve and method of use
US7713249B2 (en) 1991-12-18 2010-05-11 Icu Medical, Inc. Medical valve and method of use
US20060264891A1 (en) * 1991-12-18 2006-11-23 Icu Medical, Inc. Medical valve and method of use
US7713247B2 (en) 1991-12-18 2010-05-11 Icu Medical, Inc. Medical valve and method of use
US7717887B2 (en) 1991-12-18 2010-05-18 Icu Medical, Inc. Medical valve and method of use
US7722575B2 (en) 1991-12-18 2010-05-25 Icu Medical, Inc. Medical valve and method of use
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US7717886B2 (en) 1991-12-18 2010-05-18 Icu Medical, Inc. Medical valve and method of use
US20060206058A1 (en) * 1991-12-18 2006-09-14 Lopez George A Medical valve and method of use
US7717883B2 (en) 1991-12-18 2010-05-18 Icu Medical, Inc. Medical valve and method of use
US7717885B2 (en) 1991-12-18 2010-05-18 Icu Medical, Inc. Medical valve and method of use
US5643205A (en) * 1992-04-30 1997-07-01 Medisystems Technology Corporation Blood air trap chamber
US5605540A (en) * 1992-04-30 1997-02-25 Utterberg; David S. Blood air trap chamber
US5520640A (en) * 1992-04-30 1996-05-28 Utterberg; David S. Blood air trap chamber
US8002765B2 (en) 1995-12-15 2011-08-23 Icu Medical, Inc. Medical valve with fluid escape space
US5810792A (en) * 1996-04-03 1998-09-22 Icu Medical, Inc. Locking blunt cannula
US6916309B2 (en) 2000-07-11 2005-07-12 Icu Medical, Inc. Medical valve with positive flow characteristics
US8870850B2 (en) 2000-07-11 2014-10-28 Icu Medical, Inc. Medical connector
US7628774B2 (en) 2000-07-11 2009-12-08 Icu Medical, Inc. Needleless Medical Connector
US7763199B2 (en) 2000-07-11 2010-07-27 Icu Medical, Inc. Method of making a seal having slit formed therein
US9238129B2 (en) 2000-07-11 2016-01-19 Icu Medical, Inc. Medical connector
US20060276758A1 (en) * 2000-07-11 2006-12-07 Fangrow Thomas F Jr Medical valve with positive flow characteristics
US7497849B2 (en) 2000-07-11 2009-03-03 Icu Medical, Inc. High flow rate needleless medical connector
US8221391B2 (en) 2000-07-11 2012-07-17 Icu Medical, Inc. Needleless medical connector
US8444628B2 (en) 2000-07-11 2013-05-21 Icu Medical, Inc. Needleless medical connector
US20060264844A1 (en) * 2000-07-11 2006-11-23 Fangrow Thomas F Jr Medical valve with positive flow characteristics
US20060224127A1 (en) * 2000-07-11 2006-10-05 Fangrow Thomas F Jr Medical valve with positive flow characteristics
US20040030321A1 (en) * 2000-07-11 2004-02-12 Fangrow Thomas F. Medical valve with positive flow characteristics
US6695817B1 (en) 2000-07-11 2004-02-24 Icu Medical, Inc. Medical valve with positive flow characteristics
US6293304B1 (en) * 2000-11-27 2001-09-25 Du-Bro Products, Inc. Fuel valve
US20050197646A1 (en) * 2002-02-11 2005-09-08 Brian Connell Dialysis connector with retention and feedback features
US7708714B2 (en) 2002-02-11 2010-05-04 Baxter International Inc. Dialysis connector with retention and feedback features
US9186494B2 (en) 2004-11-05 2015-11-17 Icu Medical, Inc. Medical connector
US9884176B2 (en) 2004-11-05 2018-02-06 Icu Medical, Inc. Medical connector
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US20060270999A1 (en) * 2004-11-05 2006-11-30 Fangrow Thomas F Soft-grip medical connector
US20060264910A1 (en) * 2004-11-05 2006-11-23 Fangrow Thomas F Soft-grip medical connector
US20070112313A1 (en) * 2004-11-05 2007-05-17 Fangrow Thomas F Soft-grip medical connector
US20060271016A1 (en) * 2004-11-05 2006-11-30 Fangrow Thomas F Soft-grip medical connector
US7824393B2 (en) 2004-11-05 2010-11-02 Icu Medical, Inc. Medical connector having high flow rate characteristics
US8628515B2 (en) 2006-10-25 2014-01-14 Icu Medical, Inc. Medical connector
US8398607B2 (en) 2006-10-25 2013-03-19 Icu Medical, Inc. Medical connector
US9533137B2 (en) 2006-10-25 2017-01-03 Icu Medical, Inc. Medical connector
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