US20250221444A1 - A product comprising a permeable container and a dried extract from a plant material and uses thereof - Google Patents

A product comprising a permeable container and a dried extract from a plant material and uses thereof Download PDF

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Publication number
US20250221444A1
US20250221444A1 US18/852,714 US202318852714A US2025221444A1 US 20250221444 A1 US20250221444 A1 US 20250221444A1 US 202318852714 A US202318852714 A US 202318852714A US 2025221444 A1 US2025221444 A1 US 2025221444A1
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United States
Prior art keywords
flavour
active
aerosol
product
delivering composition
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US18/852,714
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English (en)
Inventor
Stuart Martin
John Richardson
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Nicoventures Trading Ltd
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Nicoventures Trading Ltd
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Publication of US20250221444A1 publication Critical patent/US20250221444A1/en
Assigned to Nicoventures Trading Limited reassignment Nicoventures Trading Limited ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED, MARTIN, STUART, RICHARDSON, JOHN
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    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B13/00—Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/186—Treatment of tobacco products or tobacco substitutes by coating with a coating composition, encapsulation of tobacco particles
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/302—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by natural substances obtained from animals or plants
    • A24B15/303—Plant extracts other than tobacco
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/32—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by acyclic compounds
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10—Devices using liquid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/20—Devices using solid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/42—Cartridges or containers for inhalable precursors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/04—Articles or materials wholly enclosed in single sheets or wrapper blanks
    • B65D75/06—Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks initially folded to form tubes
    • B65D75/12—Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks initially folded to form tubes with the ends of the tube closed by flattening and heat-sealing
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/30—Devices using two or more structurally separated inhalable precursors, e.g. using two liquid precursors in two cartridges

Definitions

  • the invention relates to a product comprising a permeable container and a dried extract from a plant material, methods of manufacturing the product and uses thereof.
  • Materials for use in delivery systems for delivering active substances and/or flavours may be derived from plant materials or extracts from plant materials. Factors such as the concentration of the active and/or flavour components in the materials for use in the delivery systems, and the stability of these materials, will influence the delivery of the desired components.
  • a product comprising a permeable container holding a flavour- and/or active-delivering composition comprising a dried extract from a flavour- and/or active-containing plant material.
  • the flavour- and/or active-delivering composition consists of a dried extract from a flavour- and/or active-containing plant material.
  • the flavour- and/or active-delivering composition is formed by drying a precursor composition comprising the extract from a flavour- and/or active-containing plant material.
  • flavour- and/or active-delivering composition and/or the precursor composition comprises an aerosol-former material.
  • the aerosol-former material is glycerol.
  • the precursor material is dried to a moisture content of from 0 to about 5% (calculated on a wet weight basis).
  • the precursor material comprises from about 10 to about 95% by weight extract from a flavour- or active-containing plant material.
  • the precursor material comprises from about 1 to about 36 wt % aerosol-former material.
  • the precursor material comprises from 0 to about 40% by weight of an excipient.
  • the flavour- and/or active-delivering composition comprises from about 45 to about 99% by weight dried extract from the flavour- or active-containing plant material.
  • the flavour- and/or active-delivering composition comprises from about 1 to about 34% by weight of an aerosol-former material.
  • the flavour- and/or active-delivering composition comprises from 0 to about 25% by weight of an excipient.
  • the plant material is selected from the group consisting of tobacco, eucalyptus , star anise, cocoa and hemp.
  • the extract from a flavour- or active-containing plant material is an aqueous extract.
  • the extract from a flavour- or active-containing plant material is an aqueous tobacco extract.
  • the flavour- and/or active-delivering composition comprises from about 40 to about 99% by weight tobacco solids.
  • flavour- and/or active-delivering composition is in the form of one or more selected from the group consisting of discrete particles, agglomerates or tablets.
  • the product is for use in an aerosol provision system.
  • the product is for use in an aerosol-free delivery system or for use as an aerosol-free delivery system.
  • the product is for oral use.
  • the system is configured to heat the flavour- and/or active-delivering composition to form a vapour and/or aerosol.
  • the system further comprises a further aerosol-generating material which is to be heated to form an aerosol and/or vapour, optionally wherein the further aerosol-generating material is a liquid.
  • flavour- and/or active-delivering composition is heated by the aerosol and/or vapour generated from the further aerosol-generating material.
  • the system includes a means for heating the further aerosol-generating material to form a vapour, but not including a separate means for heating the flavour- and/or active-delivering composition.
  • an aerosol-generating device comprising an area for receiving one or more products according to the first aspect, and configured to heat the one or more products in the area.
  • Karl Fischer titration is a classic method of chemical analysis for reliably determining the amount of water in a sample, and even just trace amounts. The method can be readily carried out using an automated Karl Fischer titrator. Similarly, the use of GC-TCD is also a well-established method for reliably determining the water content in a sample.
  • flavour- and/or active-delivering composition when described as hygroscopic, this means that it will rapidly absorb water from the surrounding environment to significantly increase its water content.
  • the moisture content upon exposure of the flavour- and/or active-delivering composition to the environment (for example, upon storage in an open container or the like), the moisture content rapidly increases to above 20% or above 25% (calculated on a wet weight basis), as measured by gas chromatography-thermal conductivity detector (GC-TCD) or Karl Fischer titration.
  • GC-TCD gas chromatography-thermal conductivity detector
  • Karl Fischer titration Karl Fischer titration.
  • a wrapper, bag or pouch may be flexible, for example formed from one or more sheets.
  • the sheets may be bonded to one another to seal the wrapper, bag or pouch once the portion of flavour- and/or active-delivering composition has been added.
  • the wrapper, bag or pouch forms a chamber within which the flavour- and/or active-delivering composition is sealed.
  • the sheets are formed from or consist of a moisture impermeable material, such as a polymeric sheet, a metal foil or laminate sheet, which is perforated to render it permeable.
  • the sheet material comprises a permeable or porous material, such as a porous paper, a fabric or a fleece.
  • FIG. 1 One example of a permeable pouch is shown in FIG. 1 .
  • the pouch 1 comprises two sheets 2 of porous material. These sheets are fused or adhered along their edges to form a chamber within which a flavour- and/or active-delivering composition 3 is sealed.
  • the precursor material comprises at least about 10 wt %, about 20 wt %, at least about 30 wt %, at least about 40 wt %, at least about 50 wt %, at least about 60 wt %, at least about 70 wt %, at least about 80 wt %, or at least about 90 wt % extract from a tobacco or other flavour- or active-substance containing plant material (calculated on a wet weight basis).
  • the dried flavour- and/or active-delivering composition may comprise from about 2 wt % to about 10 wt % of nicotine, or from about 3 to about 6 wt % of nicotine (calculated on a dry weight basis).
  • the precursor material may be in the form of a slurry, a suspension, a gel, a liquid or a solid, but in some embodiments which may be preferred, it is in the form of a suspension or liquid. In some embodiments, particles of solid material may be removed from the extract and/or from the precursor material by filtration and/or centrifugation.
  • the water content of the precursor material may be at least about 20 wt %, at least about 30 wt %, at least about 40 wt %, at least about 50 wt %, at least about 60 wt %, at least about 70 wt %, at least about 80 wt %, or at least about 90 wt % on a wet weight basis.
  • the water content of the precursor material may be up to about 95 wt %, up to about 90 wt %, up to about 85 wt %, up to about 80 wt %, up to about 75 wt %, up to about 70 wt %, up to about 65 wt %, up to about 60 wt %, up to about 55 wt % or up to about 50 wt % on a wet weight basis.
  • the water content of the precursor material is between about 40 and about 50 wt % on a wet weight basis (50% and 60 v/v %). When the precursor material has a lower water content, the spray/freeze-drying process is quicker, as there is less water to remove.
  • the dried flavour- and/or active-delivering composition and/or the precursor material comprises one or more active substance. This may be derived from the extract or it may be added. In some embodiments, the extract from a flavour- or active-substance containing plant material comprises an active substance.
  • the active substance comprises nicotine. In some embodiments, the active substance comprises caffeine, melatonin or vitamin B12.
  • the precursor material may comprise an extract from other botanical source(s) along with or instead of the tobacco extract.
  • the mint may be chosen from the following mint varieties: Mentha Arventis, Mentha c.v., Mentha niliaca, Mentha piperita, Mentha piperita citrata c.v., Mentha piperita c.v., Mentha spicata crispa, Mentha cardifolia, Mentha longifolia, Mentha suaveolens variegata, Mentha pulegium, Mentha spicata c.v. and Mentha suaveolens
  • the extract comprises or is derived from one or more botanicals or constituents, derivatives or extracts thereof selected from eucalyptus , star anise, cocoa and hemp.
  • the extract comprises or is derived from one or more botanicals or constituents, derivatives or extracts thereof selected from rooibos and fennel.
  • the flavour- and/or active-delivering composition and/or the precursor material comprises one or more cannabinoid compounds selected from the group consisting of: cannabidiol (CBD), tetrahydrocannabinol (THC), tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), cannabinol (CBN), cannabigerol (CBG), cannabichromene (CBC), cannabicyclol (CBL), cannabivarin (CBV), tetrahydrocannabivarin (THCV), cannabidivarin (CBDV), cannabichromevarin (CBCV), cannabigerovarin (CBGV), cannabigerol monomethyl ether (CBGM) and cannabielsoin (CBE), cannabicitran (CBT).
  • CBD cannabidiol
  • THC tetrahydrocannabinol
  • THCA te
  • the flavour- and/or active-delivering composition and/or the precursor material may comprise one or more cannabinoid compounds selected from the group consisting of cannabidiol (CBD) and THC (tetrahydrocannabinol).
  • CBD cannabidiol
  • THC tetrahydrocannabinol
  • the flavour- and/or active-delivering composition and/or the precursor material may comprise nicotine, cannabidiol (CBD), and THC (tetrahydrocannabinol).
  • the flavour- and/or active-delivering composition and/or the precursor material comprises one or more excipients in an amount of from 0 to about 40 wt % on a wet weight basis.
  • the precursor material may comprise at least about 1 wt %, at least about 10 wt %, at least about 20 wt %, at least about 30 wt %, and/or up to about 40 wt %, up to about 30%, up to about 20 wt %, or up to about 10 wt % excipient on a wet weight basis.
  • the flavour- and/or active-delivering composition may comprise at least about 0.1 wt %, at least about 10 wt %, at least about 20 wt %, or at least about 25 wt % excipient (calculated on a dry weight basis). In some embodiments, the flavour- and/or active-delivering composition may comprise up to about 25%, up to about 20 wt %, up to about 15 wt %, or up to about 10 wt % excipient (calculated on a dry weight basis).
  • flavour- and/or active-delivering composition and/or the precursor material comprises one or more other functional materials, which may comprise one or more of pH regulators, colouring agents, preservatives, fillers, stabilizers, and/or antioxidants.
  • the flavour- and/or active-delivering composition and/or the precursor material contains a filler component.
  • the filler component is generally a non-tobacco component, that is, a component that does not include ingredients originating from tobacco.
  • the precursor material comprises less than 60 wt % of a filler, such as from 1 wt % to 60 wt %, or 5 wt % to 50 wt %, or 5 wt % to 30 wt %, or 10 wt % to 20 wt % on a wet weight basis.
  • the filler may comprise one or more inorganic filler materials such as calcium carbonate, perlite, vermiculite, diatomaceous earth, colloidal silica, magnesium oxide, magnesium sulphate, magnesium carbonate, and suitable inorganic sorbents, such as molecular sieves.
  • the filler may comprise one or more organic filler materials such as wood pulp, hemp fibre, cellulose and cellulose derivatives.
  • the gelling agent comprises (or is) one or more of hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose (HPMC), carboxymethylcellulose, guar gum, or acacia gum.
  • the gelling agent comprises (or is) one or more non-cellulosic gelling agents, including, but not limited to, agar, xanthan gum, gum Arabic, guar gum, locust bean gum, pectin, carrageenan, starch, alginate, and combinations thereof.
  • the non-cellulose based gelling agent is alginate or agar.
  • the flavour- and/or active-delivering composition and/or the precursor material may comprise an acid.
  • the acid may be an organic acid.
  • the acid may be at least one of a monoprotic acid, a diprotic acid and a triprotic acid.
  • the acid may contain at least one carboxyl functional group.
  • the acid may be at least one of an alpha-hydroxy acid, carboxylic acid, dicarboxylic acid, tricarboxylic acid and keto acid.
  • the acid may be an alpha-keto acid.
  • the acid may be at least one of succinic acid, lactic acid, benzoic acid, citric acid, tartaric acid, fumaric acid, levulinic acid, acetic acid, malic acid, formic acid, sorbic acid, benzoic acid, propanoic and pyruvic acid.
  • the acid is selected from one of lactic acid, benzoic acid and levulinic acid.
  • the acid may be an inorganic acid. In some of these embodiments the acid may be a mineral acid. In some such embodiments, the acid may be at least one of sulphuric acid, hydrochloric acid, boric acid and phosphoric acid.
  • an acid is may be beneficial in embodiments in which the flavour- and/or active-delivering composition and/or the precursor material comprises nicotine.
  • the presence of an acid may stabilise dissolved species in the slurry from which the aerosol-generating material is formed.
  • the presence of the acid may reduce or substantially prevent evaporation of nicotine during drying of the slurry, thereby reducing loss of nicotine during manufacturing.
  • the dried flavour- and/or active-delivering composition may be in any solid form.
  • the flavour- and/or active-delivering composition may be in the form of particles, granules or powder.
  • the flavour- and/or active-delivering composition may be in the form of a monolithic form, tablet, agglomerate or “cake”.
  • the flavour- and/or active-delivering composition is formed by freeze- or spray-drying and is then processed with other suitable steps as required and known to the person skilled in the art to provide the dried material in the desired form, for example in the form of particles of the desired size(s).
  • the flavour- and/or active-delivering composition is in the form of granules.
  • the granules may be of any size, cross-sectional shape or mass.
  • the flavour- and/or active-delivering composition in the form of granules is advantageous due to the high surface area to volume ratio, which positively impacts the release of components including the flavour and/or active from the material.
  • the particles in the precursor composition may be desirable for the particles in the precursor composition, to have an average particle size of no greater than about 3 mm, no greater than 1 mm, no greater than 500 ⁇ m, no greater than about 200 ⁇ m, no greater than 100 ⁇ m, no greater than about 50 ⁇ m, no greater than 40 ⁇ m, no greater than about 30 ⁇ m, no greater than 20 ⁇ m, no greater than about 10 ⁇ m, no greater than about 5 ⁇ m, or to have an average particle size of no greater than about 1 ⁇ m, when measured by sieving.
  • the average particle size is within the range of from about 0.1 ⁇ m to about 1 mm, from about 1 ⁇ m to about 500 ⁇ m, from about 10 ⁇ m to about 200 ⁇ m, from about 10 ⁇ m to about 100 ⁇ m, or in the range of from about 10 ⁇ m to about 50 ⁇ m. In some embodiments, at least about 90% of the particles of the precursor composition will have a particle size within the range of from about 1 ⁇ m to about 1 mm, or from about 10 to about 500 ⁇ m, or from about 50 to about 200 ⁇ m.
  • At least about 90% of the tobacco particles of the precursor composition will have a particle size within the range of from about 1 ⁇ m to about 1 mm, or from about 10 to about 500 ⁇ m, or from about 50 to about 200 ⁇ m. In some embodiments, at least about 90% of the tobacco particles of the precursor composition will have a particle size within the range of from about 1 ⁇ m to about 1 mm, or from about 10 to about 500 ⁇ m, or from about 50 to about 200 ⁇ m. In some embodiments, at least about 90% of the tobacco particles of the precursor composition will have a particle size within the range of from about 1 ⁇ m to about 1 mm, or from about 10 to about 500 ⁇ m, or from about 50 to about 200 ⁇ m.
  • none of the particles in the precursor composition have a particle size greater than 1 mm, greater than 0.5 mm, greater than 0.2 mm, greater than 0.15 mm, or greater than about 0.1 mm. In some embodiments, the average particle size is less than 50 ⁇ m.
  • the freeze dried precursor material is ground into particles and may be sieved to exclude particles that are considered too small or too large to be used as flavour- and/or active-delivering composition.
  • the drying methods used to dry the precursor material may be any suitable drying process, including freeze-drying or spray-drying processes.
  • the drying process used must be compatible with the precursor material and the desired make-up of the flavour- and/or active-delivering composition.
  • it may be desirable for the flavour- and/or active-delivering composition to include active and/or flavour substances derived from the extract in the precursor material it is important to select a drying method that will retain a sufficient amount of these components.
  • the precursor material is sprayed and rapidly dried using a hot gas.
  • spray drying provides several advantages to the present invention: the dry particle size can be controlled and may be consistent; tobacco or flavour extracts or materials are heat sensitive but can still be spray-dried at relatively high inlet temperatures; a short residence time in the spray-drying equipment is required; and minimal loss of flavour/volatiles. This makes the process adaptable to reduce loss of volatile compounds and maintain the desired flavour of the flavour- and/or active-delivering composition.
  • the composition may comprise an aerosol-former material.
  • this aerosol-former material is included in the precursor material.
  • the aerosol-former material may be added to the dried flavour- and/or active-delivering composition.
  • the precursor material comprises at least about 1 wt %, at least about 5 wt %, at least about 10 wt %, or at least about 20 wt %, aerosol-former material (calculated on a wet weight basis). Additionally or alternatively, the precursor material may comprise up to about 40 wt %, up to about 35, up to about 30 wt %, up to about 25 wt %, up to about 20 wt %, or up to about 10 wt % aerosol-former material (calculated on a wet weight basis).
  • glycerol and some other aerosol-former materials are considered to have anti-freeze properties, it is particularly surprising that it is possible to freeze-dry a precursor material comprising such materials. Nevertheless, the inventors have discovered that precursor materials comprising glycerol may be freeze dried to form a highly useful flavour- and/or active-delivering composition.
  • the container and/or the flavour- and/or active-delivering composition comprises one or more additives that are released upon heating the flavour- and/or active-delivering composition and which therefore contribute to the generated aerosol.
  • the total mass of the flavour- and/or active-delivering composition included may be at least about 5 mg, at least about 10 mg, at least about 15 mg, at least about 20 mg, at least about 25 mg, at least about 30 mg, at least about 35 mg, at least about 40 mg, at least about 45 mg, or at least about 50 mg.
  • the total mass of the flavour- and/or active-delivering composition is sufficient to provide aerosol, for example, for up to about 10 puffs to be generated in a single session or over a series of multiple sessions.
  • the total mass of the dried aerosol-generating material provided is from about 10 to 100 mg, or from about 25 to about 50 mg.
  • the flavour- and/or active-delivering composition is combined with a further aerosol-generating material, such as a material comprising tobacco.
  • a further aerosol-generating material such as a material comprising tobacco.
  • the flavour- and/or active-delivering composition may be combined with tobacco material.
  • the tobacco may be pre-processed or unprocessed, and may be, for instance, solid stems (SS); shredded dried stems (SDS); steam treated stems (STS); or any combination thereof.
  • the tobacco material may be fermented, cured, uncured, toasted, or otherwise pre-treated.
  • the tobacco material may be provided in the form of cut rag tobacco.
  • the cut rag tobacco can have a cut width of at least 15 cuts per inch (about 5.9 cuts per cm, equivalent to a cut width of about 1.7 mm) for example.
  • the cut rag tobacco can be formed from a mixture of forms of tobacco material, for instance a mixture of one or more of paper reconstituted tobacco, leaf tobacco, extruded tobacco and band
  • the heating material may be heated by induction heating.
  • Induction heating is a process in which an electrically-conductive object is heated by penetrating the object with a varying magnetic field.
  • the heating material may be heated by resistive heating.
  • the heating material is connected to a power supply.
  • the heating may be microwave heating or infrared heating.
  • the heating material is surrounded by the flavour- and/or active-delivering composition.
  • the heating material is in the form of a mesh or a perforated sheet, a strip or ribbon.
  • the heating material is in particulate form.
  • the heating material is a coating on the flavour- and/or active-delivering composition or on the container. It may be preferable for the heating material to be in contact with the flavour- and/or active-delivering composition.
  • the products comprising a container containing the flavour- and/or active-delivering composition may be used in combustible or non-combustible aerosol provision systems.
  • the products are used as a consumable or are included in a consumable.
  • the high concentration of flavour and/or active provided by the flavour- and/or active-delivering composition of the present disclosure means that, upon heating, the composition is able to provide an aerosol comprising a high concentration of these desirable components.
  • the small quantity of the composition required means that the aerosol can be generated rapidly once the heating has started, as the mass of composition to be heated is very small.
  • the heating of these compositions is very energy efficient as there may be little material in the compositions that does not contribute to the aerosol.
  • a consumable is an article comprising an aerosol-generating material, part or all of which is intended to be consumed during use by a user.
  • aerosol-generating material or at least part of the aerosol-generating material is the flavour- and/or active-delivering composition, and is provided in a container as disclosed herein. Further aerosol-generating material may be provided in the container or elsewhere in the consumable.
  • flavour- and/or active-delivering composition may be used as or referred to as an aerosol-generating material.
  • a consumable may comprise one or more other components, such as an aerosol-generating material storage area, an aerosol-generating material transfer component, an aerosol generation area, a housing, a wrapper, a mouthpiece, a filter and/or an aerosol-modifying agent.
  • a consumable may also comprise an aerosol generator, such as a heater, that emits heat to cause the aerosol-generating material to generate aerosol in use.
  • the heater may, for example, comprise a material heatable by electrical conduction, or a susceptor.
  • the heater may, in some embodiments, be provided within the container with the flavour- and/or active-delivering composition. In some embodiments, the heater may form part of the container.
  • delivery system is intended to encompass systems that deliver at least one substance to a user, and includes:
  • the disclosure relates to a component for use in a combustible aerosol provision system, such as a filter, a filter rod, a filter segment, a tobacco rod, a spill, an aerosol-modifying agent release component such as a capsule, a thread, or a bead, or a paper such as a plug wrap, a tipping paper or a cigarette paper.
  • a component for use in a combustible aerosol provision system such as a filter, a filter rod, a filter segment, a tobacco rod, a spill, an aerosol-modifying agent release component such as a capsule, a thread, or a bead, or a paper such as a plug wrap, a tipping paper or a cigarette paper.
  • a “non-combustible” aerosol provision system is one where a constituent aerosol-generating material of the aerosol provision system (or component thereof) is not combusted or burned in order to facilitate delivery of at least one substance to a user.
  • the delivery system is a non-combustible aerosol provision system, such as a powered non-combustible aerosol provision system.
  • the non-combustible aerosol provision system is an electronic cigarette, also known as a vaping device or electronic nicotine delivery system (END), although it is noted that the presence of nicotine in the aerosol-generating material is not a requirement.
  • END electronic nicotine delivery system
  • the non-combustible aerosol provision system is an aerosol-generating material heating system, also known as a heat-not-burn system.
  • a heat-not-burn system is a tobacco heating system.
  • the non-combustible aerosol provision system may comprise a non-combustible aerosol provision device and a consumable for use with the non-combustible aerosol provision device.
  • the disclosure relates to consumables comprising a container comprising an aerosol-generating material and configured to be used with non-combustible aerosol provision devices.
  • consumables are sometimes referred to as articles throughout the disclosure.
  • the non-combustible aerosol provision system may comprise an area or a chamber for receiving the consumable, an aerosol generator, an aerosol generation area, a housing, a mouthpiece, a filter and/or an aerosol-modifying agent.
  • the area or chamber for receiving the consumable may be surrounded by a heat source, so that heat is transferred to the consumable and the aerosol-generating material held therein.
  • heat from another source within the device may be transferred to the consumable within the chamber or area.
  • the consumable for use with the non-combustible aerosol provision device may comprise a composition comprising an aerosol-generating material and a moisture impermeable coating, an aerosol-generating material storage area, an aerosol-generating material transfer component, an aerosol generator, an aerosol generation area, a housing, a wrapper, a filter, a mouthpiece, and/or an aerosol-modifying agent.
  • the substance to be delivered may be an aerosol-generating material provided within a container, and optionally another aerosol-generating material that may or may not be heated.
  • the aerosol-generating material in the container and any other aerosol-generating material may comprise one or more active constituents, one or more flavours, one or more aerosol-former materials, and/or one or more other functional materials.
  • the permeable container containing a flavour- and/or active-delivering composition is used to provide the aerosol-generating material is a tobacco heating system. This may be instead of or in addition to another aerosol-generating material, such as a tobacco composition.
  • the container and or the flavour- and/or active-delivering composition may be heated directly or indirectly to generate an aerosol from the flavour- and/or active-delivering composition.
  • the permeable nature of the container means that this does not need to be removed or opened prior to use.
  • the contents of the container may be sufficient to provide aerosol for a single puff or for a series of puffs.
  • the contents of the container provides 6 to 9 puffs of aerosol when heated.
  • the flavour- and/or active-delivering composition generates an aerosol with a high concentration of flavour and/or active. This can provide an authentic tobacco taste and nicotine delivery.
  • the very small size of the container and the very concentrated nature of the flavour- and/or active-delivering composition means that the aerosol provision system may be designed to be small and discreet. As discussed above, the amount of energy required to operate the system is much smaller than the energy required by conventional tobacco heating devices. Further, the aerosol generated is much more satisfying with the high concentration of flavour and/or active.
  • FIG. 2 shows a cross-sectional view of an example of a tobacco heating product for heating an aerosol-generating material.
  • the apparatus 11 has a heating chamber 14 which in use contains the permeable container 13 containing the flavour- and/or active-delivering composition to be heated and volatilised.
  • the apparatus 11 of FIG. 2 further has an electronics/power chamber 16 which may, for example, contain electrical control circuitry and/or a power source (not shown).
  • the electrical control circuitry may include a controller, such as a microprocessor arrangement, configured and arranged to control the heating of the smokable material via a heating element (not shown).
  • the electrical control circuitry may in use receive a signal from, for example, a puff-actuated sensor which is sensitive to for example changes in pressure or changes in rate of air flow that occur upon initiation of a draw on the apparatus 11 by a user. The electrical control circuitry can then operate so as to cause heating of the flavour- and/or active-delivering composition “on demand”.
  • a puff-actuated sensor including for example a thermistor, an electro-mechanical device, a mechanical device, an optical device, an opto-mechanical device and a micro electro mechanical systems (MEMS) based sensor.
  • the apparatus may have a manually operable switch for a user to initiate a puff.
  • the heating chamber 14 is contained within the housing 12 .
  • the housing 12 includes an inlet 15 through which air is drawn into the apparatus.
  • the housing 12 also includes an outlet 17 at a mouthpiece 18 of the apparatus 11 .
  • Air is drawn into the apparatus 11 through the inlet 15 , travels through the apparatus and through the container 13 , picking up the aerosol released by the flavour- and/or active-delivering composition.
  • the resulting aerosol generated by the apparatus 11 leaves the apparatus 11 through the outlet 19 and is inhaled by the user.
  • the non-combustible aerosol provision system is a hybrid system to generate aerosol using a combination of aerosol-generating materials, one or a plurality of which may be heated and may be a composition comprising an aerosol-generating material and a moisture impermeable coating.
  • Each of the aerosol-generating materials may be, for example, in the form of a solid, liquid or gel and may or may not contain nicotine.
  • the hybrid system comprises a liquid or gel aerosol-generating material and a solid aerosol-generating material.
  • the solid aerosol-generating material may comprise, for example, tobacco or a non-tobacco product.
  • the permeable container containing a flavour- and/or active-delivering composition is used in a hybrid system and the flavour- and/or active-delivering composition is heated by a vapour that is generated by the system and is drawn through the permeable container. Additionally or alternatively, the flavour- and/or active-delivering composition may be directly heated by a further heat source. In such embodiments, the flavour- and/or active-delivering composition adds concentrated flavour and/or active to the aerosol, such as an authentic tobacco taste and nicotine delivery.
  • FIG. 3 shows a cross-sectional view of an example of a Hybrid product for heating a flavour- and/or active-delivering composition and a liquid.
  • the apparatus 21 has a housing 22 containing a chamber 24 which in use contains a container containing the flavour- and/or active-delivering composition 23 to be heated and volatilised.
  • the housing 22 also contains a liquid reservoir 25 containing a liquid 26 to be heated to form a vapour.
  • the apparatus 21 further has an electronics/power chamber 27 which may, for example, contain electrical control circuitry and/or a power source (not shown).
  • the electrical control circuitry may include a controller, such as a microprocessor arrangement, configured and arranged to control the heating of the container 23 and/or its contents, and of the liquid 26 via one or more heating elements (not shown).
  • the electrical control circuitry may allow the apparatus 21 to be puff-actuated, so as to cause heating “on demand”.
  • the apparatus 22 may have a manually operable switch for a user to initiate a puff.
  • the housing 22 also includes an inlet 28 through which air is drawn into the apparatus.
  • the housing 22 also includes an outlet 29 at a mouthpiece 30 of the apparatus 21 . Air is drawn into the apparatus 21 through the inlet 28 , travels through the apparatus picking up the vapour created by heating the liquid 26 in the liquid reservoir 25 , and flavour and/or active components released by the container 23 , and the resulting aerosol generated by the apparatus 21 leaves the apparatus 21 through the outlet 29 and is inhaled by the user.
  • the Hybrid device 21 shown schematically in FIG. 3 represents just one possible configuration of such an apparatus.
  • the relative positions of the liquid reservoir 25 and the chamber 24 for holding the container 23 can be changed, as can the path of the air flowing through the apparatus.
  • the liquid reservoir is positioned upstream of the smokable material to be volatilised.
  • the liquid reservoir may be positioned downstream of the smokable material to be volatilised.
  • the two sources of aerosol in the apparatus may be arranged side-by-side, etc.
  • the products comprising a permeable container containing a flavour- and/or active-delivering composition may be used in an aerosol-free delivery system or as an aerosol-free delivery system.
  • Aerosol-free delivery systems are those that deliver at least one substance to a user orally, nasally, transdermally or in another way without forming an aerosol, including but not limited to, lozenges, gums, patches, articles comprising inhalable powders, and oral products such as oral tobacco which includes snus or moist snuff, wherein the at least one substance may or may not comprise nicotine.
  • the products disclosed herein may be configured for oral use, to provide oral delivery of the flavour- and/or active.
  • the permeable container is provided in a form such that during oral use, saliva in the mouth of the user enters through the permeable container and contacts the flavour- and/or active-delivering composition.
  • the saliva causes the flavour and/or active components to be released from the flavour- and/or active-delivering composition, and saliva containing the released components is able to pass out of the container, so that they may be perceived in the mouth and/or absorbed into the bloodstream, either via the mucosal membranes in the oral cavity or by being swallowed by the user.
  • the permeable container comprises or consists of a water-permeable pouch.
  • the highly concentrated nature of the flavour- and/or active-delivering composition means that the container can be very small, such as a “micro pouch” with dimensions that are smaller than the conventional pouches provided for oral use, such as snus or moist snuff. As a result, these tiny pouches are discreet and can be more comfortable for use. Also, the amount of saliva required to release the flavour and/or active components may be much smaller than in conventional products. This means that the release of the components may be much faster, providing a more rapid effect for the user. In fact, in some embodiments, the release of the components may commence as soon as within less than about 5 minutes, less than about 4 minutes, less than about 3 minutes, less than about 2 minutes, less than about 1 minute, or less than about 30 seconds from placing the product in the mouth.
  • use of the product may, in some embodiments, be much more satisfying with the high concentration of flavour and/or active.
  • the container holds not only the flavour- and/or active-delivering composition but also an additional flavour and/or active source, such as a tobacco formulation.
  • the tobacco formulation may be a formulation similar to one used in know oral tobacco products.
  • the flavour- and/or active-delivering composition provides an additional release of flavour and/or active component(s), in addition to the components delivered by the tobacco formulation.
  • the flavour- and/or active-delivering composition may provide an initial “hit” of flavour and/or active, in advance of the slower and more sustained release form the tobacco formulation.
  • the product comprises a moisture impermeable coating that surrounds but which may be separate from the flavour- and/or active-delivering composition.
  • the moisture impermeable coating may surround the flavour- and/or active-delivering composition.
  • the moisture impermeable coating may be provided as a film or wrapper, optionally being deposited on a moisture permeable carrier.
  • the product comprises a sorbent or desiccant material.
  • the sorbent or desiccant material may be provided in the flavour- and/or active-delivering composition as discussed above. Alternatively, these components may be provided separately in the product, but in such a manner that the sorbent still competes with the flavour- and/or active-delivering composition for the moisture in the environment and therefore reduces the amount of moisture absorbed by the flavour- and/or active-delivering composition.
  • the sorbent may be provided in or on a wrapper that surrounds the flavour- and/or active-delivering composition in the product. In other embodiments, the sorbent may be incorporated into a separate section of the product to the flavour- and/or active-delivering composition.
  • the product is to be heated to generate an aerosol
  • this may have the benefit of reducing the exposure of the sorbent to the high temperatures that the aerosol-generating material is heated to upon use.
  • the sorbent may be located in an adjacent section of the product which is not directly heated. This may be downstream or upstream of the aerosol-generating material.
  • the sorbent is included in one or more sections of the product that does not include the aerosol-generating material, such as a cooling element section, or a filter section.
  • the sorbent may be separated or removed from the flavour- and/or active-delivering composition and/or from the product before it is used.
  • the sorbent may be located in the packaging within which the product is held prior to use. In some embodiments, this packaging may be a wrapper, a box or other container.
  • the sorbent may be incorporated into the packaging material or part thereof.
  • the sorbent may be provided in a separate article, such as a sachet or sheet, located with the product within the packaging.
  • the invention enjoys the advantage of longer shelf life than other tobacco extracts.
  • the nicotine content of the precursor and flavour- and/or active-delivering composition after the freeze drying process has been calculated, providing an indication of the amount of nicotine retained following the processing.
  • the nicotine recovery of the dried flavour- and/or active-delivering composition is at least about 76 wt % on a dry weight basis.
  • the nicotine recovery of the dried flavour- and/or active-delivering composition compared to the original tobacco extract may be at least about 60%, at least about 70%, at least about 75%, at least about 80%, or at least about 90% on a dry weight basis.
  • the glycerol content of the precursor and dried flavour- and/or active-delivering composition after the freeze drying process has been calculated, providing an indication of the amount of glycerol retained following the processing.
  • the glycerol recovery of the dried flavour- and/or active-delivering composition is at least about 85%.
  • the glycerol recovery of the dried flavour- and/or active-delivering composition compared to the precursor material may be at least about 70%, at least about 75%, at least about 80%, at least about 85%, at least about 90% at least about 95% on a dry weight basis.

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US18/852,714 2022-04-01 2023-03-31 A product comprising a permeable container and a dried extract from a plant material and uses thereof Pending US20250221444A1 (en)

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US7726320B2 (en) * 2006-10-18 2010-06-01 R. J. Reynolds Tobacco Company Tobacco-containing smoking article
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US10532046B2 (en) * 2015-12-03 2020-01-14 Niconovum Usa, Inc. Multi-phase delivery compositions and products incorporating such compositions
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