US20250204579A1 - A substrate comprising an aerosol-generating material surrounded by a support and uses thereof - Google Patents

A substrate comprising an aerosol-generating material surrounded by a support and uses thereof Download PDF

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Publication number
US20250204579A1
US20250204579A1 US18/852,694 US202318852694A US2025204579A1 US 20250204579 A1 US20250204579 A1 US 20250204579A1 US 202318852694 A US202318852694 A US 202318852694A US 2025204579 A1 US2025204579 A1 US 2025204579A1
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US
United States
Prior art keywords
aerosol
substrate
generating material
support
generating
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Pending
Application number
US18/852,694
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English (en)
Inventor
Stuart Martin
Barry Dimmick
Jeremy Campbell
Matthew Hodgson
Robert Press
John Richardson
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Nicoventures Trading Ltd
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Nicoventures Trading Ltd
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Publication of US20250204579A1 publication Critical patent/US20250204579A1/en
Assigned to Nicoventures Trading Limited reassignment Nicoventures Trading Limited ASSIGNMENT OF ASSIGNOR'S INTEREST Assignors: CAMPBELL, JEREMY, HODGSON, MATTHEW, BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED, PRESS, ROBERT, MARTIN, STUART, DIMMICK, Barry, RICHARDSON, JOHN
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/281—Treatment of tobacco products or tobacco substitutes by chemical substances the action of the chemical substances being delayed
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/302—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by natural substances obtained from animals or plants
    • A24B15/303—Plant extracts other than tobacco
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/32—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by acyclic compounds
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/36—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring
    • A24B15/40—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms
    • A24B15/403—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms having only oxygen as hetero atoms
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES OF CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D1/00—Cigars; Cigarettes
    • A24D1/20—Cigarettes specially adapted for simulated smoking devices

Definitions

  • the invention relates to substrates comprising an aerosol-generating material surrounded by a support, methods of manufacturing the substrates and uses thereof.
  • Aerosol-generating materials for use in a combustible or a non-combustible aerosol provision system may include a variety of different active substances and/or flavours. Factors such as the concentration of volatile active and/or flavour components in the aerosol generating materials and the stability of the aerosol-generating materials will influence the properties of the aerosol generated.
  • a substrate comprising an aerosol-generating material surrounded by a support, the aerosol-generating material comprising a dried precursor material comprising an extract from a flavour- and/or active-containing plant material.
  • the support comprises a sheet and the aerosol generating material is sandwiched between one or more of the sheets.
  • the sheet comprises one or more selected from the group consisting of: paper; card; paperboard; cardboard; reconstituted material; a plastics material; a ceramic material; activated carbon; glass; a sintered material; a composite material; a plant-derived material; a fabric or fleece; a fibrous tow; a metal; and a metal alloy.
  • the substrate has a rolled configuration.
  • the aerosol generating material is distributed within the support.
  • the support is a porous material with the aerosol-generating material distributed within the pores.
  • the support is a fibrous material.
  • the fibrous material is selected from the group consisting of: a fibrous tow; a non-woven sheet; a porous paper; and a fabric or fleece.
  • the support comprises an agglomerated material.
  • the substrate is an extruded mixture of the support and the aerosol-generating material.
  • the support comprises tobacco material.
  • the support comprises a heating material.
  • the substrate does not include a binder applied to adhere the aerosol-generating material to the support.
  • a binder is included to adhere the aerosol-generating material to the support, in an amount of from about 0.1 wt % to about 5 wt %, based on the entire weight of the aerosol-generating material.
  • the binder is selected from the group consisting of: thermoreversible gelling agents; starches; polysaccharides; pectins; celluloses; cellulose derivatives; and alginates.
  • the aerosol-generating material comprises from about 1 to about 34% by weight aerosol-former material.
  • the support comprises one or more rolled sheets, with the aerosol-generating material located between layers of the sheet(s). Two such configurations are shown in FIGS. 1 and 2 .
  • the sheet used as a support may have a surface that is smooth, or a surface that is rough or porous.
  • a rough or porous surface may be advantageous where the aerosol-generating material is not adhered to the sheet using a binder, or is not provided as a layer bound to the surface of the sheet.
  • the aerosol generating material is distributed within the support.
  • the support or part thereof may be formed from a rough or porous paper material, such as tipping paper, porous plug wrap, cigarette paper or tea bag paper.
  • the paper may be a porous paper.
  • the particles may nestle into the pores of the porous paper to provide good adhesion between the solid surfaces of the particles and the paper.
  • the support surface comprises a paper material, the paper optionally having a weight of from about 20 gsm to about 100 gsm.
  • the support is or comprises an air-laid paper.
  • This has a highly porous surface structure and in some embodiments, the aerosol-generating material is applied to the surface of the air-laid paper. In other embodiments, the aerosol-generating material may be added during the manufacture of the air-laid paper, the manufacturing process being a dry process.
  • the aerosol-generating material is added to the porous support as the support material is manufactured.
  • the support material is a non-woven sheet, such as a paper, fabric or reconstituted material (such as a sheet of reconstituted tobacco)
  • the aerosol-generating material may be incorporated into the sheet as it is formed. This may again lead to the aerosol-generating material being embedded in and distributed throughout the support material of the substrate.
  • the support comprises an agglomerated material. This means that it is possible to distribute or embed the aerosol-generating material within the agglomerated support material.
  • the mixture is agglomerated by extrusion.
  • the agglomeration process is dry, i.e. the components to be agglomerated are dry and there is no addition of a liquid component.
  • One such dry agglomeration process is dry extrusion, where the components to be extruded are combined without any additional liquid component. In dry extrusion, the shear forces applied to the extruded composition can be sufficient to cause fusion or binding to form a stable agglomerate.
  • a liquid may be added to lubricate the mixture being agglomerated.
  • water may be added as a processing aid.
  • the presence of water may help to dissolve components of the composition to be agglomerate, and/or it may assist with binding or improve agglomeration.
  • the liquid may comprise an aerosol-former material.
  • the aerosol-former material may be one of the aerosol-former materials discussed elsewhere herein.
  • Another liquid that may be included to assist agglomeration is a liquid extract from a flavour- and/or active-containing plant material. These liquids may be used in addition to or instead of conventional liquid agglomeration aids.
  • the agglomeration process exposes the material to be agglomerated to conditions under which the precursor material may be dried.
  • One such agglomeration process is extrusion, during which the mixture is exposed to heat and high shear forces that can have a drying effect.
  • the support material to be agglomerated may be mixed with either the (already dried) aerosol-generating material, or with the precursor material, or with a combination of both. The subsequent agglomeration step will dry any precursor material present in the mixture to form the aerosol-generating material.
  • the agglomerated support material comprises tobacco material, for example, tobacco material in the form of particles.
  • the tobacco particles have a size small enough to ensure that multiple such particles can be agglomerated to form a substrate having desired dimensions based upon their intended use. Smaller tobacco particles have a greater surface area to volume ratio and they may therefore exhibit enhanced release of tobacco constituents compared to particles of larger sizes.
  • the size of the tobacco particles (and of other particles in the composition to be agglomerated) will have an effect on the porosity and density of the agglomerated structures and the substrates formed therefrom.
  • the size of the tobacco particles may be selected to produce an agglomerated structure with the desired porosity, which will have an impact on the release of the tobacco constituents from the tobacco support material as well as the aerosol from the aerosol-generating material which is surrounded by the support.
  • the extrusion processes used to form the agglomerated structures can be sensitive to the size of the particles within the composition being extruded. Therefore, it may be desirable for the particles in the composition to be extruded, for example including tobacco particles as the support material, to have an average particle size of no greater than about 0.5 mm, or to have an average particle size of no greater than about 0.3 mm, when measured by sieving. In some embodiments, it may be desirable for the particles in the composition to be extruded to have an average particle size of no greater than about 0.5 mm, or to have an average particle size of no greater than about 0.3 mm, when measured by sieving.
  • the tobacco material used to form the particles of support material may be any type of tobacco and any part of the tobacco plant, including tobacco lamina, stem, stalk, ribs, scraps and shorts or mixtures of two or more thereof. Suitable tobacco materials include the following types: Virginia or flue-cured tobacco, Burley tobacco, Oriental tobacco, or blends of tobacco materials, optionally including those listed here.
  • the tobacco may be expanded, such as dry-ice expanded tobacco (DIET), or processed by any other means.
  • the tobacco material may be reconstituted tobacco material.
  • the tobacco may be pre-processed or unprocessed, and may be, for instance, solid stems (SS); shredded dried stems (SDS); steam treated stems (STS); or any combination thereof.
  • the tobacco material may be fermented, cured, uncured, toasted, or otherwise pre-treated.
  • the agglomerated support may have an increased surface area by including in the composition to be agglomerated particles of an inert filler material.
  • Suitable inert fillers may be porous or non-porous.
  • the composition to be agglomerated does not include a binder or binding additive.
  • the composition to be agglomerated comprises a binder or binding additive.
  • the binding additive may be selected to assist in the formation of an agglomerated structure by helping to adhere the components in the composition to one another.
  • Suitable binding additives include, for example, starches, polysaccharides, pectins, celluloses, cellulose derivatives such as carboxymethylcellulose, and alginates. Other suitable binders are those discussed elsewhere herein.
  • the support consists of or comprises a heating material that comprises one or more materials selected from the group consisting of: an electrically-conductive material, a magnetic material, and a magnetic electrically-conductive material.
  • the heating material may comprise a metal or a metal alloy.
  • the heating material may comprise one or more materials selected from the group consisting of: aluminium, gold, iron, nickel, cobalt, conductive carbon, graphite, plain-carbon steel, stainless steel, ferritic stainless steel, copper, and bronze.
  • the heating material may be heated by induction heating.
  • Induction heating is a process in which an electrically-conductive object is heated by penetrating the object with a varying magnetic field.
  • the heating material may be heated by resistive heating.
  • the heating material is connected to a power supply.
  • the heating may be microwave heating or infrared heating.
  • the heating material is a strip or ribbon embedded in the support. In some embodiments, the heating material a rough surface, or holes, for example in the form of a mesh or a perforated sheet. In some embodiments, the heating material is in particulate form.
  • the heating material is in the form of a coating applied to one or more other components of the support.
  • a key consideration in this invention is balancing the trapping of the aerosol-generating material within the support material, whilst still providing the aerosol-generating material in a form that can volatilise during heating to generate the desired aerosol and/or vapour.
  • This requires space for the aerosol-generating material, and so the support needs to be sufficiently porous to provide this space.
  • This porosity is also required to ensure that the aerosol and/or vapour generated by heating the aerosol-generating material can be released from the substrate. It is therefore important for the substrate to have pores and channels to permit the aerosol and/or vapour generation and release.
  • the surface roughness of the sheet will contribute to the required porosity of the substrate.
  • Surface roughness is a component of surface texture and it is generally quantified by the deviations in the direction of the normal vector of a real surface from its ideal form.
  • the profile roughness parameters are included in BS EN ISO 4287:2000 British standard, which is identical to the ISO 4287:1997 standard.
  • One test of surface smoothness (or roughness) is the Bekk smoothness which is measured by an air leak method in which a test surface is clamped between a flat glass plate and a circular metal head and air is drawn across the surface of the test piece under a partial vacuum. The rate of airflow is measured in ml/minute between the paper and the applicable standards are ISO 5627, Tappi T479 and DIN 53107.
  • high “loft” materials may be particularly suitable for ensuring good aerosolisation. Folding, creping or embossing of the various sheet materials disclosed herein may provide these materials with additional loft to benefit aerosol generation and release from the substrates formed using such support materials.
  • the aerosol-generating material comprises a dried extract from a flavour- and/or active-containing plant material.
  • the aerosol-generating material further comprises an aerosol-former material.
  • the aerosol-generating material is formed by drying a precursor material comprising an extract from a flavour- and/or active-containing plant material.
  • the drying process is selected to retain the desired components of the precursor material and, therefore, the aerosol-generating material may comprise one or more active substances and/or flavours.
  • the precursor material further comprises one or more aerosol-former material. Additionally or alternatively, one or more aerosol-former materials may be added to the dried precursor material to provide an aerosol-generating material with the desired aerosol-former material content.
  • the extract from a flavour- or active-substance containing plant material is an extract derived by contacting the plant material with a suitable solvent, such as an aqueous solvent or an alcohol such as ethanol.
  • a suitable solvent such as an aqueous solvent or an alcohol such as ethanol.
  • the liquid portion comprising the solvent and any dissolved plant components may then be separated or partially separated from the remaining solid plant material to provide the extract to be included in the precursor composition and dried.
  • the aerosol-generating material may comprise one or more active substances and/or flavours, and optionally one or more aerosol-former materials.
  • the precursor material and/or the dried aerosol-generating material may also optionally include one or more other functional materials.
  • the invention enjoys the advantage of an aerosol-generating material that is formulated to have an increased shelf life and so it may be easily transported and stored. Without wishing to be bound by any particular theory, it is hypothesised that the low water content of the dried aerosol-generating material reduces evaporation over time of other solvents, and reduces degradation of nicotine and/or other volatile compounds. A low water content also inhibits microbial growth.
  • compositions comprising the dried aerosol-generating materials described herein are stable at a range of temperatures and humidities and have an increased shelf-life, and are therefore easy to store and transport.
  • the compositions may be stored at temperatures in the range of 0-35° C.
  • the compositions may be stored at a relative humidity of up to about 30%, or even as high as 50%, prior to use.
  • the aerosol-generating materials also have the advantage of having a high concentration of the desired components. This means that relatively small amounts of the aerosol-generating material are required and less energy is required to heat and release the desired components. Significantly, the aerosols generated from these materials also provide an authentic tobacco taste of reasonable strength.
  • a further advantage of the aerosol-generating materials is that they may be used as a solid aerosol-generating substrate in Hybrid systems or Tobacco Heating Products (THPs). This makes the invention versatile enough to be used in a range of products without the need for further processing.
  • THPs Tobacco Heating Products
  • the extract from a flavour- or active-substance containing plant material is an extract derived from tobacco material.
  • the tobacco extract or material may be from or may be any type of tobacco and any part of the tobacco plant, including tobacco lamina, stem, stalk, ribs, scraps and shorts or mixtures of two or more thereof. Suitable tobacco extracts or materials include the following types: Virginia or flue-cured tobacco, Burley tobacco, Oriental tobacco, or blends of tobacco materials, optionally including those listed here.
  • the tobacco may be expanded, such as dry-ice expanded tobacco (DIET), or processed by any other means.
  • the tobacco material may be reconstituted tobacco material.
  • the tobacco may be pre-processed or unprocessed, and may be, for instance, solid stems (SS); shredded dried stems (SDS); steam treated stems (STS); or any combination thereof.
  • the tobacco material may be fermented, cured, uncured, toasted, or otherwise pre-treated.
  • the tobacco material may be provided in the form of cut rag tobacco.
  • the cut rag tobacco can have a cut width of at least 15 cuts per inch (about 5.9 cuts per cm, equivalent to a cut width of about 1.7 mm) for example.
  • the cut rag tobacco can be formed from a mixture of forms of tobacco material, for instance a mixture of one or more of paper reconstituted tobacco, leaf tobacco, extruded tobacco and bandcast tobacco.
  • the precursor material which is dried to form the aerosol-generating material may comprise at least about 10 wt %, at least about 15 wt %, at least about 20 wt %, at least about 25 wt %, at least about 30 wt %, at least about 35 wt %, or at least about 40 wt % tobacco solids (calculated on a wet weight basis). Additionally or alternatively, the precursor material may comprise up to about 60 wt %, up to about 55 wt %, up to about 50 wt %, up to about 45 wt %, or up to about 40 wt % tobacco solids (calculated on a wet weight basis). In some embodiments, the precursor material comprises from about 20 wt % to about 40 wt % tobacco solids (calculated on a wet weight basis).
  • the precursor material comprises at least about 10 wt %, about 20 wt %, at least about 30 wt %, at least about 40 wt %, at least about 50 wt %, at least about 60 wt %, at least about 70 wt %, at least about 80 wt %, or at least about 90 wt % extract from a tobacco or other flavour- or active-substance containing plant material (calculated on a wet weight basis).
  • precursor material may comprise up to about 99 wt %, up to about 90 wt %, up to about 80 wt %, up to about 70 wt % or up to about 60 wt % extract from tobacco or other flavour- or active-substance containing plant material (calculated on a wet weight basis).
  • the precursor material comprises around 50 wt % tobacco extract (calculated on a wet weight basis).
  • the aerosol-generating material may comprise at least about 45 wt %, at least about 50 wt %, at least about 60 wt %, at least about 70 wt %, at least about 80 wt %, at least about 90 wt %, or at least about 95 wt % tobacco material or tobacco extract, or flavour- or active-substance containing plant material extract (calculated on a dry weight basis). In some embodiments, the aerosol-generating material may comprise about 60 to about 80 wt % tobacco extract (calculated on a dry weight basis).
  • the dried aerosol-generating material may comprise from about 2 wt % to about 10 wt % nicotine, or from about 3 to about 6 wt % of nicotine (calculated on a dry weight basis).
  • the precursor material comprises around 50 v/v % tobacco extract.
  • the precursor material comprises around 50 v/v % tobacco extract and the tobacco extract has a tobacco solid content of between about 55 and about 60 v/v %
  • the overall tobacco solid content of the precursor material is from about 27.5 to about 30 v/v %.
  • the tobacco extract has a solids content of between about 40 and about 65 wt %, between about 45 and about 65 wt %, or between about 40 and about 60 wt % (calculated on a wet weight basis).
  • the water content of the tobacco extract is between about 35 wt % and about 65 wt %, or between about 35 and about 55 wt % (calculated on a wet weight basis).
  • the nicotine content of the tobacco extract is between about 1 wt % and about 5 wt % (calculated on a wet weight basis).
  • the dried aerosol-generating material may comprise at least about 45 wt %, at least about 50 wt %, at least about 60 wt %, at least about 70 wt %, at least about 80 wt %, at least about 90 wt %, or at least about 95 wt % tobacco solids (calculated on a dry weight basis). Additionally or alternatively, the aerosol-generating material may comprise up to about 99 wt %, up to about 98 wt %, up to about 95 wt %, up to about 90 wt % or up to about 80 wt %. In some embodiments, the dried aerosol-generating material may comprise about 60 to about 80 wt % tobacco solids (calculated on a dry weight basis).
  • any particles in the precursor composition may be desirable for any particles in the precursor composition to have an average particle size of no greater than about 3 mm, of no greater than 1 mm, of no greater than about 0.5 mm, or to have an average particle size of no greater than about 0.3 mm, when measured by sieving or by observing the size of the particles by SEM.
  • the dried aerosol-generating material and/or the precursor material comprises one or more active substance. This may be derived from the extract or it may be added. In some embodiments, the extract from a flavour- or active-substance containing plant material comprises an active substance.
  • the active substance may be a physiologically active material, which is a material intended to achieve or enhance a physiological response.
  • the active substance may for example be selected from nutraceuticals, nootropics and psychoactives.
  • the active substance may comprise, for example, nicotine, caffeine, taurine, theine, vitamins such as B6 or B12 or C, melatonin, cannabinoids, or constituents, derivatives, or combinations thereof.
  • the active substance may comprise one or more constituents, derivatives or extracts of tobacco, cannabis or another botanical.
  • the active substance comprises nicotine. In some embodiments, the active substance comprises caffeine, melatonin or vitamin B12.
  • the precursor material may comprise an extract from other botanical source(s) along with or instead of the tobacco extract.
  • the extract may comprise or be derived from one or more botanicals or constituents, derivatives or extracts thereof.
  • botanical includes any material derived from plants including, but not limited to, extracts, leaves, bark, fibres, stems, roots, seeds, flowers, fruits, pollen, husk, shells or the like.
  • the extract may comprise or be derived from botanicals in the form of liquid, gas, solid, powder, dust, crushed particles, granules, pellets, shreds, strips, sheets, or the like.
  • Example botanicals are tobacco, eucalyptus , star anise, hemp, cocoa, cannabis , fennel, lemongrass, peppermint, spearmint, rooibos, chamomile, flax, ginger, Ginkgo biloba , hazel, hibiscus, laurel, licorice (liquorice), matcha, mate, orange skin, papaya , rose, sage, tea such as green tea or black tea, thyme, clove, cinnamon, coffee, aniseed (anise), basil, bay leaves, cardamom, coriander, cumin, nutmeg, oregano, paprika, rosemary, saffron, lavender, lemon peel, mint, juniper, elderflower, vanilla, wintergreen, beefsteak plant, curcuma , turmeric, sandalwood, cilantro, bergamot, orange blossom, myrtle, cassis, valerian, pimento, mace, damien, marjoram
  • the mint may be chosen from the following mint varieties: Mentha Arventis, Mentha c.v., Mentha niliaca, Mentha piperita, Mentha piperita citrata c.v., Mentha piperita c.v., Mentha spicata crispa, Mentha cardifolia, Mentha longifolia, Mentha suaveolens variegata, Mentha pulegium, Mentha spicata c.v. and Mentha suaveolens
  • the extract comprises or is derived from one or more botanicals or constituents, derivatives or extracts thereof selected from eucalyptus , star anise, cocoa and hemp.
  • the aerosol-generating material and/or the precursor material comprises one or more cannabinoid compounds selected from the group consisting of: cannabidiol (CBD), tetrahydrocannabinol (THC), tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), cannabinol (CBN), cannabigerol (CBG), cannabichromene (CBC), cannabicyclol (CBL), cannabivarin (CBV), tetrahydrocannabivarin (THCV), cannabidivarin (CBDV), cannabichromevarin (CBCV), cannabigerovarin (CBGV), cannabigerol monomethyl ether (CBGM) and cannabielsoin (CBE), cannabicitran (CBT).
  • CBD cannabidiol
  • THC tetrahydrocannabinol
  • THCA tetrahydroc
  • the aerosol-generating material and/or the precursor material may comprise one or more cannabinoid compounds selected from the group consisting of cannabidiol (CBD) and THC (tetrahydrocannabinol).
  • CBD cannabidiol
  • THC tetrahydrocannabinol
  • the aerosol-generating material and/or the precursor material may comprise cannabidiol (CBD).
  • CBD cannabidiol
  • the aerosol-generating material and/or the precursor material may comprise nicotine, cannabidiol (CBD), and THC (tetrahydrocannabinol).
  • the aerosol-generating material further comprises an aerosol-former material.
  • this aerosol-former material is included in the precursor material.
  • the aerosol-former material may comprise one or more constituents capable of forming an aerosol.
  • the aerosol-former may be, for instance, a polyol aerosol generator or a non-polyol aerosol generator. It may be a solid or liquid at room temperature, but preferably is a liquid at room temperature.
  • the aerosol-former material may comprise one or more of glycerine, glycerol, propylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, 1,3-butylene glycol, erythritol, meso-Erythritol, ethyl vanillate, ethyl laurate, a diethyl suberate, triethyl citrate, triacetin, a diacetin mixture, benzyl benzoate, benzyl phenyl acetate, tributyrin, lauryl acetate, lauric acid, myristic acid, and propylene carbonate.
  • the aerosol former comprises one or more polyhydric alcohols, such as propylene glycol, triethylene glycol, 1,3-butanediol and glycerin; esters of polyhydric alcohols, such as glycerol mono-, di- or triacetate; and/or aliphatic esters of mono-, di- or polycarboxylic acids, such as dimethyl dodecanedioate and dimethyl tetradecanedioate.
  • the aerosol-former material comprises one or more compounds selected from erythritol, propylene glycol, glycerol, vegetable glycerine (VG), triacetin, sorbitol and xylitol.
  • the aerosol-former material comprises, consists essentially of or consists of glycerol.
  • Glycerol provides a visible aerosol when the aerosol-generation device is used. It is common that consumers like the aerosol generating device to provide a visible aerosol, as this enables the consumer to visualise the product and what they are consuming. This makes glycerol a desirable choice for aerosol former material.
  • Propylene glycol has the benefit that it is a better flavour carrier than glycerol.
  • a combination of two or more aerosol forming agents may be used, in equal or differing proportions.
  • the precursor material comprises at least about 1 wt %, at least about 5 wt %, at least about 10 wt %, or at least about 20 wt %, aerosol-former material (calculated on a wet weight basis). Additionally or alternatively, the precursor material may comprise up to about 40 wt %, up to about 35, up to about 30 wt %, up to about 25 wt %, up to about 20 wt %, or up to about 10 wt % aerosol-former material (calculated on a wet weight basis).
  • the precursor material may comprise at most 36 wt % of glycerol.
  • the inventors have demonstrated that dry weight inclusion levels up to 36 wt % (calculated on a dry weight basis) of aerosol-former material are possible.
  • the amount of glycerol in the precursor material, and therefore the dried aerosol material is important because it is both an aerosol-forming material and also a plasticizer. If the concentration of glycerol it too high, it may be detrimental to a critical temperature of the product during the freeze-drying process and may result in collapse of the product if the critical temperature of the formulation is exceeded. On the other hand, sufficient glycerol should be included to provide the consumer with an adequate and pleasing aerosol.
  • glycerol and some other aerosol-former materials are considered to have anti-freeze properties, it is particularly surprising that it is possible to freeze-dry a precursor material comprising such materials. Nevertheless, the inventors have discovered that precursor materials comprising glycerol may be freeze dried to form a highly useful aerosol-generating material.
  • the dried aerosol-generating material may comprise at least about 1 wt %, at least about 5 wt %, at least about 10 wt %, at least about 20 wt %, at least about 30 wt %, or at least about 40 wt % aerosol-former material (calculated on a dry weight basis).
  • the dried aerosol-generating material may comprise from about 1 to about 34 wt %, or from about 17 to about 34 wt % aerosol-former material (calculated on a dry weight basis). In some embodiments in which the aerosol-former material is glycerol, the dried aerosol-generating material may comprise from about 13 to about 34 wt % glycerol (calculated on a dry weight basis).
  • the aerosol-generating material may comprise from about 17 to about 36 wt % of glycerol.
  • the amount of glycerol in the aerosol material is important because it is both an aerosol-forming material and a plasticizer. If the concentration of glycerol is too high, it may be detrimental to the critical temperature of the product during the freeze-drying process and may result in collapse of the product if a critical temperature of the formulation is exceeded. On the other hand, sufficient glycerol should be included to provide the consumer with an adequate and pleasing aerosol.
  • the aerosol-generating material and/or the precursor material further comprises one or more excipients.
  • the excipient stabilises and preserves the precursor material and the inventors have found the inclusion of an excipient especially important for stability when the precursor material comprised glycerol as the aerosol-forming material.
  • the excipient may also act as a bulking agent or a filler material.
  • the inclusion of an excipient may also improve the handleability of the dried aerosol-generating material, helping it to retain its granular form by helping to reduce moisture uptake and the resulting increase in tackiness of the material.
  • the presence of an excipient may also have an effect on the speed of (freeze) drying.
  • the aerosol-generating material and/or the precursor material comprises one or more excipients in an amount of from 0 to about 40 wt % on a wet weight basis.
  • the precursor material may comprise at least about 1 wt %, at least about 10 wt %, at least about 20 wt %, at least about 30 wt %, and/or up to about 40 wt %, up to about 30%, up to about 20 wt %, or up to about 10 wt % excipient on a wet weight basis.
  • the aerosol-generating material may comprise at least about 0.1 wt %, at least about 10 wt %, at least about 20 wt %, or at least about 25 wt % excipient (calculated on a dry weight basis). In some embodiments, the aerosol-generating material may comprise up to about 25%, up to about 20 wt %, up to about 15 wt %, or up to about 10 wt % excipient (calculated on a dry weight basis).
  • the aerosol-generating material comprises about 36 wt % glycerol, about 45 wt % tobacco extract, and about 19 wt % excipient on a dry weight basis.
  • the precursor material may comprise about 0 wt %, about 5 wt %, or about 10 wt % agar.
  • agar makes the precursor material more viscous and that the freeze-drying process is easier when the precursor material comprises a lower concentration of the agar excipient.
  • the precursor material comprises about 50 wt % tobacco extract, from 0 to about 36 wt % aerosol forming agent (for example, from 0 to about 15 v/v %) and from 0 to about 40 wt % (for example, about 37.5 v/v %) excipient.
  • the tobacco extract may comprise about 55 wt % tobacco solids and the overall tobacco solids content of the precursor material is about 27.5 wt %.
  • Some sample formulations of dried aerosol-generating materials formed from aqueous tobacco extracts are summarised in Table 1 below, with the amounts provided on a dry weight basis. These are theoretical values (before drying and inherent losses). Typically from about 80 to 89% of the glycerol is retained following the drying. Glycerol may be used as an aerosol-former material, but can be replaced or partially replaced with one or more other aerosol-former material such as those disclosed herein.
  • the excipient used may be a dextran such as Dextran 70. Again, this may be replaced or partially replaced with alternative excipients, such as those disclosed herein.
  • Tobacco extract including Aerosol-former Excipient Nicotine nicotine (%) material (%) (%) (%) (%) 100 0 0 4.8-9.2 85-70 15-30 0 3.6-7.3 80-70 0 20-30 3.8-6.5 45-70 10-36 16-25 3-5
  • the percentage content of nicotine in the formulation will depend on the type of tobacco used, and the presence of other components, i.e. the aerosol-former and the excipient.
  • the aerosol-generating material comprises one or more binders.
  • the one or more binder is selected from the group consisting of: thermoreversible gelling agents, such as gelatin; starches; polysaccharides; pectins; celluloses; cellulose derivatives, such as carboxymethylcellulose; and alginates.
  • the amount of binder used to adhere the aerosol-generating material to the support is from about 1 to about 30% by weight based on the weight of the aerosol-generating material. In some embodiments, the amount of binder used is up to about 20%, up to about 15%, up to about 10% by weight of the aerosol-generating material. Additionally or alternatively, the amount of binder when used may be at least about 1%, at least about 2%, at least about 5% or at least about 8% by weight of the aerosol-generating material
  • the aerosol-generating material and/or the precursor material comprises one or more flavour-modifier, flavour or flavourant.
  • flavour-modifier derived from the extract or it may be added.
  • flavourant refers to materials which, where local regulations permit, may be used to create a desired taste, aroma or other somatosensorial sensation in a product for adult consumers.
  • flavour materials may include naturally occurring flavour materials, botanicals, extracts of botanicals, synthetically obtained materials, or combinations thereof (e.g., tobacco, cannabis , licorice (liquorice), hydrangea , eugenol, Japanese white bark magnolia leaf, chamomile, fenugreek, clove, maple, matcha, menthol, Japanese mint, aniseed (anise), cinnamon, turmeric, Indian spices, Asian spices, herb, wintergreen, cherry, berry, red berry, cranberry, peach, apple, orange, mango, clementine, lemon, lime, tropical fruit, papaya , rhubarb, grape, durian, dragon fruit, cucumber, blueberry, mulberry, citrus fruits, Drambuie, bourbon, scotch, whiskey, gin, tequila, rum, spearmint, peppermint, lavender, aloe vera, cardamom, celery, cascarilla, nutmeg, sandalwood, berg
  • the flavour comprises menthol, spearmint and/or peppermint.
  • the flavour comprises flavour components of cucumber, blueberry, citrus fruits and/or redberry.
  • the flavour comprises eugenol.
  • the flavour comprises flavour components extracted from tobacco.
  • the flavour comprises flavour components extracted from cannabis.
  • the flavour may comprise a sensate, which is intended to achieve a somatosensorial sensation which are usually chemically induced and perceived by the stimulation of the fifth cranial nerve (trigeminal nerve), in addition to or in place of aroma or taste nerves, and these may include agents providing heating, cooling, tingling, numbing effect.
  • a suitable heat effect agent may be, but is not limited to, vanillyl ethyl ether and a suitable cooling agent may be, but not limited to eucolyptol, WS-3.
  • the aerosol-generating material and/or the precursor material contains a filler component.
  • the filler component is generally a non-tobacco component, that is, a component that does not include ingredients originating from tobacco.
  • the precursor material comprises less than 60 wt % of a filler, such as from 1 wt % to 60 wt %, or 5 wt % to 50 wt %, or 5 wt % to 30 wt %, or 10 wt % to 20 wt % on a wet weight basis.
  • the dried aerosol-generating material is in the form of a gel.
  • a gelling agent may be added to the aerosol-generating material, the precursor material or may be optionally omitted.
  • the gelling agent may comprise one or more compounds selected from cellulosic gelling agents, non-cellulosic gelling agents, guar gum, acacia gum and mixtures thereof.
  • the aerosol-generating material comprises a gelling agent comprising a cellulosic gelling agent and/or a non-cellulosic gelling agent, an active substance and an acid.
  • the dried aerosol-generating material may be in any solid form.
  • the aerosol-generating material may be in the form of particles, granules or powder.
  • the aerosol-generating material may be in the form of a monolithic form, tablet, agglomerate or “cake”.
  • the aerosol-generating material formed by freeze- or spray-drying and is then processed with other suitable steps as required and known to the person skilled in the art to provide the dried material in the desired form, for example in the form of particles of the desired size(s).
  • the aerosol-generating material is in the form of particles or granules.
  • the granules may be of any size, cross-sectional shape or mass.
  • the aerosol-generating material in the form of granules is advantageous due to the high surface area to volume ratio, which positively impacts the release of volatiles from the material. This form also facilitates incorporation of the material into an aerosol provision system.
  • Smaller granule particles have a greater surface area to volume ratio and they may therefore exhibit enhanced release of tobacco constituents compared to particles of larger sizes. They will also have a greater tendency to adhere to surfaces, such as the rough surface of the support.
  • the average particle size is within the range of from about 0.1 ⁇ m to about 1 mm, from about 0.1 ⁇ m to about 500 ⁇ m, from about 10 ⁇ m to about 200 ⁇ m, from about 10 ⁇ m to about 100 ⁇ m, or in the range of from about 10 ⁇ m to about 50 ⁇ m. In some embodiments, at least about 90% of the particles of the precursor composition will have a particle size within the range of from about 1 ⁇ m to about 1 mm, or from about 10 to about 500 ⁇ m, or from about 50 to about 200 ⁇ m.
  • At least about 90% of the tobacco particles of the precursor composition will have a particle size within the range of from about 1 ⁇ m to about 1 mm, or from about 10 to about 500 ⁇ m, or from about 50 to about 200 ⁇ m. In some embodiments, none of the particles in the precursor composition have a particle size greater than 1 mm, greater than 0.5 mm, greater than 0.2 mm, greater than 0.15 mm, or greater than about 0.1 mm. In some embodiments, the average particle size is less than 50 ⁇ m.
  • the particle size of any solid material present may be reduced by grinding, shredding, cutting or crushing tobacco material.
  • Suitable machinery to create such plant particles includes, for example, shredders, cutters, or mills, such as hammer mills, roller mills or other types of commercially available milling machinery.
  • the size of the plant particles is selected to provide particles which can be readily prepared from a variety of different types of plant material, having the properties described herein, and which provide a source of plant constituents that are readily released.
  • Particles of the aerosol-generating material of a smaller size may be advantageous for aerosol generation.
  • smaller particles may have a greater surface area to volume ratio, which may improve aerosol generation.
  • the dried aerosol-generating material readily forms particles with an average size of smaller than 1 mm.
  • the particles may be as small as 10 ⁇ m or even as small as 1 ⁇ m. The size of the particles may be determined by sieving or by observing the particles by SEM.
  • the particles of the aerosol-generating material may be preferred. Particle adhesion between particles and a surface, or between particles involves a variety of different forces, including van der Waals forces, diffusion, mechanical interaction and electrostatic attraction. At least some of these forces are generally stronger the greater the surface energy of the particles and this is related to the size of the particles. Essentially, smaller particles tend to be more “sticky”. Therefore, in some embodiments, the particles of the aerosol-generating material have a particle size of no greater than 50 ⁇ m, no greater than 40 ⁇ m, no greater than 30 ⁇ m, no greater than 20 ⁇ m or no greater than to ⁇ m. Such small particle sizes also mean that the rough surface of the support does not need to have large pores or irregularities to accommodate particles of such dimensions.
  • the freeze dried precursor material is ground into particles and may be sieved to exclude particles that are considered too small or too large to be used as aerosol-generating material.
  • aerosol-generating material used in the present invention has a particle size distribution D10 from about 5 to about 25 ⁇ m (meaning that 10% of the particles in the tested sample are smaller than the value), a particle size distribution D50 from about 30 to about 200 ⁇ m (meaning that 50% of the particles in the tested sample are smaller than the value), and a particle size distribution D90 from about 500 to about 2500 ⁇ m (meaning that 90% of the particles in the tested sample are smaller than the value).
  • D10 from about 5 to about 25 ⁇ m (meaning that 10% of the particles in the tested sample are smaller than the value)
  • a particle size distribution D50 from about 30 to about 200 ⁇ m (meaning that 50% of the particles in the tested sample are smaller than the value)
  • a particle size distribution D90 from about 500 to about 2500 ⁇ m (meaning that 90% of the particles in the tested sample are smaller than the value).
  • the freeze dried material used as the aerosol-generating material according to the present invention has a particle size distribution D10 from about 8 to about 15 ⁇ m, a particle size distribution D50 from about 50 to about 150 ⁇ m, and a particle size distribution D90 from about 900 to about 1700 ⁇ m.
  • the D10 mean is from about 10 to about 15 ⁇ m
  • the D50 mean from about 40 to about 140 ⁇ m
  • the D90 mean from about 800 to about 1600 ⁇ m.
  • the drying methods used to dry the precursor material may be any suitable drying process, including freeze-drying or spray-drying processes.
  • the drying process used must be compatible with the precursor material and the desired make-up of the aerosol-generating material.
  • it may be desirable for the aerosol-generating material to include active and/or flavour substances derived from the extract in the precursor material it is important to select a drying method that will retain a sufficient amount of these components.
  • the precursor material is freeze-dried using freeze-drying microscopy, for example using a Lyostat freeze-drying microscope.
  • the precursor material is sprayed and rapidly dried using a hot gas.
  • spray drying provides several advantages to the present invention: the dry particle size can be controlled and may be consistent; tobacco or flavour extracts or materials are heat sensitive but can still be spray-dried at relatively high inlet temperatures; a short residence time in the spray-drying equipment is required; and minimal loss of flavour/volatiles. This makes the process adaptable to reduce loss of volatile compounds and maintain the desired flavour of the aerosol generating material.
  • Freeze-drying also known as lyophilisation or cryodesiccation, is a process in which the precursor material is frozen, the temperature lowered and the water is removed via sublimation under reduced pressure conditions. Without wishing to be bound by any specific theory, it is believed that the low processing temperatures and rapid water loss via sublimation avoid changes in the aerosol-generating material's structure, appearance and characteristics. This process preserves the structure of the precursor material, and reduces the loss and decomposition of volatile flavour compounds.
  • the dried aerosol-generating material has a lower water content than the precursor material.
  • the water content of the aerosol-generating material may be at most about 0.5 wt %, about 1 wt %, about 2%, about 5 wt %, about 10 wt %, or about 20 wt % (calculated on a wet weight basis).
  • the water content of the dried aerosol-generating material may be reduced from the precursor material by at least about 50 wt %, about 60 wt %, about 70 wt %, about 80 wt %, about 90 wt %, about 95 wt %, about 98 wt %, or by about 100 wt %.
  • the dried aerosol-generating material has a water content of less than about 5 wt %, less than about 4 wt %, less than about 3 wt %, less than about 2 wt % or less than about 1 wt % (calculated on a wet weight basis), as measured by gas chromatography-thermal conductivity detector (GC-TCD) or Karl Fischer measurement.
  • GC-TCD gas chromatography-thermal conductivity detector
  • the precursor material comprises Burley tobacco extract and a water content of 60 wt %.
  • the dried aerosol generating material has a water content of 3 wt %.
  • a lower water content of the dried aerosol-generating material is associated with longer shelf-life and stability. However, very low water content may be associated be a brittle structure and a smaller particle size, as well as taking longer to process.
  • the material is also very hygroscopic. If the water content of the dried aerosol-generating material is too high on the other hand, the desired increased stability may not be achieved.
  • the dried aerosol-generating material may also not be as easy to handle with higher water content, with the material becoming sticky.
  • the precursor material comprises an excipient
  • the precursor material may be better suited to being dried via spray-drying (compared to a precursor material without an excipient).
  • increasing the amount of the excipient in the precursor material raises the glass transition temperature to above 100° C. and this affects the physical properties of the material, making it more suitable for spray drying.
  • the substrates comprising the aerosol-generating material and support may be used in combustible or non-combustible aerosol provision systems, or in an aerosol-free delivery system.
  • the present invention also relates to a consumable or article, comprising an aerosol-generating material surrounded by a support.
  • the substrate is provided in a consumable.
  • the substrate may be used as a consumable.
  • a consumable is an article comprising aerosol-generating material, part or all of which is intended to be consumed during use by a user.
  • the aerosol-generating material, or at least some of the aerosol-generating material is provided as part of a substrate as disclosed herein, comprising the aerosol-generating material and a support.
  • a consumable may comprise one or more other components, such as an aerosol-generating material storage area, an aerosol-generating material transfer component, an aerosol generation area, a housing, a wrapper, a mouthpiece, a filter and/or an aerosol-modifying agent.
  • a consumable may also comprise an aerosol generator, such as a heater, that emits heat to cause the aerosol-generating material to generate aerosol in use.
  • the heater may, for example, comprise combustible material, a material heatable by electrical conduction, or a susceptor.
  • at least some of these components of a consumable may also be components of the substrate described herein.
  • the consumable may be any shape or size that is appropriate to the aerosol-generating device.
  • the consumable is a rod shape. In other embodiments, it may take the form of a flat strip, a tube, a disc, or a flexible sleeve.
  • the substrate comprising an aerosol-generating material and a support is provided in an aerosol-generating device such as a tobacco-heating product (THP) or hybrid e-cigarette product.
  • an aerosol-generating device such as a tobacco-heating product (THP) or hybrid e-cigarette product.
  • the substrate may be directly heated without burning to provide an inhalable aerosol.
  • heating the substrate will first cause the coating to decompose, to breach the barrier it forms around the aerosol-generating material. Then, the aerosolised components of the aerosol-generating material, for example the glycerol, nicotine and/or tobacco flavour will be released.
  • the substrate comprising an aerosol-generating material and a support may be incorporated into the consumable in the absence of any other carrier or other material that would need to be heated.
  • the substrate comprises multiple layers, for example in the form of a laminate.
  • the substrate may comprise alternating layers of support material and aerosol-generating material.
  • further layers of different material may be included, such as layers of a further, different aerosol-generating material, or a layer comprising an aerosol-modifying agent, such as a flavour.
  • the consumable comprises a moisture impermeable coating that surrounds but which may be separate from the aerosol-generating material.
  • the moisture impermeable coating may surround the substrate (thereby surrounding the aerosol-generating material within the composition).
  • the moisture impermeable coating may be provided as a film or wrapper, optionally being deposited on a moisture permeable carrier.
  • the consumable comprises a sorbent or desiccant material.
  • the sorbent or desiccant material may be provided in the substrate as discussed above.
  • these components may be provided separately in the consumable, but in such a manner that the sorbent still competes with the aerosol-generating material for the moisture in the environment and therefore reduces the amount of moisture absorbed by the aerosol-generating material.
  • the sorbent may be provided in or on a wrapper that surrounds the aerosol generating material in the consumable.
  • the sorbent may be incorporated into a separate section of the consumable to the aerosol-generating material. This may have the benefit of reducing the exposure of the sorbent to the high temperatures that the aerosol-generating material is heated to upon use.
  • the sorbent may be located in an adjacent section of the consumable which is not directly heated. This may be downstream or upstream of the aerosol-generating material.
  • the sorbent is included in one or more sections of the consumable that does not include the aerosol-generating material, such as a cooling element section, or a filter section.
  • a “combustible” aerosol provision system is one where a constituent aerosol-generating material of the aerosol provision system (or component thereof) is combusted or burned during use in order to facilitate delivery of at least one substance to a user.
  • the non-combustible aerosol provision system is a hybrid system to generate aerosol using a combination of aerosol-generating materials, one or a plurality of which may be heated and may be an aerosol-generating material provided on a support.
  • Each of the aerosol-generating materials may be, for example, in the form of a solid, liquid or gel and may or may not contain nicotine.
  • the hybrid system comprises a liquid or gel aerosol-generating material and a solid aerosol-generating material.
  • the solid aerosol-generating material may comprise, for example, tobacco or a non-tobacco product.

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