US20240001102A1 - Open electric pump - Google Patents
Open electric pump Download PDFInfo
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- US20240001102A1 US20240001102A1 US18/368,045 US202318368045A US2024001102A1 US 20240001102 A1 US20240001102 A1 US 20240001102A1 US 202318368045 A US202318368045 A US 202318368045A US 2024001102 A1 US2024001102 A1 US 2024001102A1
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- pump
- frame
- rotor
- blood
- electromagnetic coils
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/135—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/403—Details relating to driving for non-positive displacement blood pumps
- A61M60/419—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being permanent magnetic, e.g. from a rotating magnetic coupling between driving and driven magnets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/13—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/135—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
- A61M60/139—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting inside the aorta, e.g. intra-aortic balloon pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
- A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/403—Details relating to driving for non-positive displacement blood pumps
- A61M60/422—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/538—Regulation using real-time blood pump operational parameter data, e.g. motor current
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
- A61M60/81—Pump housings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
- A61M60/857—Implantable blood tubes
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/12—Blood circulatory system
Definitions
- the present disclosure is directed to open electric pumps used to pump fluids. Specifically, the present disclosure describes an open electric pump that may be implanted in a failing heart to assist in the pumping of blood.
- circulatory assist devices have been developed in order to aid a failing heart to pump blood.
- Such devices can include rotary axial flow pumps, or centrifugal pumps, that have rotors which pumps blood by spinning.
- These conventional pumps also include casings that surround the rotor with very small tolerances between the rotor and the casing wall. This “closed” design results in severe resistance to blood flow if the motor of the conventional pump stops pumping, which can occur if an associated battery pack becomes drained or if the conventional pump itself malfunctions.
- the conventional pump To maintain circulation if the pump stops pumping, the conventional pump must be used in parallel to the natural blood flow of the heart, usually from the apex of the left ventricle to the ascending or descending aorta.
- Other parallel pump-configurations from a main pumping chamber or a pre-chamber to the aorta or pulmonary artery are also being used for left or right heart support. This parallel configuration allows the natural heart to eject and support circulation even if the pump is temporarily stopped.
- Implanting a conventional pump in series with the blood flow from the heart can lead to catastrophic circulatory collapse if the conventional pump stops pumping, such as during a battery exchange, an inadvertent disconnection of the battery, or pump malfunction. This is because the closed design of conventional pumps allows very little blood to pass through them when the pump is stopped.
- Conventional pumps also include coils that generate heat, which is transferred to the surrounding tissue and blood by the casing. This can case the blood and surrounding tissue to warm to the point of causing damage to blood proteins and other cellular blood components, possibly leading to clotting and a thromboembolism.
- the present disclosure is directed to a pump that has an “open” design to allow placement of the pump in series with blood flow from the heart.
- the open design of the pump also allows for a larger, more efficient rotor that pumps blood effectively at lower rotor speeds, resulting in less shear forces on the blood and its cellular components and therefore in less trauma.
- the open design of the pump greatly reduces resistance to blood flow in the event of a pump stoppage, minimizing the risk of circulatory collapse.
- the inventive pump described herein may be placed in, for example, the left or right ventricular outflow tract or within the position of an outflow valve of the right or left ventricle without any of the negative effects of conventional pumps.
- the open design further provides for better heat exchange and potentially less blood trauma than conventional pumps due to the larger surface area exposed to the blood.
- a much larger portion of the surface of the electromagnetic coils is in contact with the blood stream that in conventional pumps. This allows for a better heatsink function and less warming of the blood components, and reduces the likelihood of thromboembolic complications.
- the inventive open pump can also be configured so that endovascular/minimally invasive placement from within the blood stream is possible.
- an implantable pump is configured to be implanted in series with blood flow from a heart.
- the pump includes a frame configured to be implanted in a ventricular outflow tract of the heart, and a central axle configured to be affixed within the frame parallel to the blood flow.
- the pump also includes a rotor attached to the central axle and configured to rotate in order to pump blood, and at least two electromagnetic coils configured to be energized in order to cause the rotor to rotate.
- the timing of the electrical pulses to propel the pump rotor are based either on hall sensors or back electromagnetic pulse sensing (back EMP sensing) from the rotating magnets passing the coils.
- the pump is controlled by an electromechanical or electronic external control unit (not shown in pictures) which has the ability to adjust the pump rotary speed by manual control and also can have automatically adjustable variable pump speed features that adjust the rotary speed based on patient sensor input, such as the patient's heart rate, with a sensor for the electrical activity of the patient's heart (such as in an electrocardiogram) or with motion sensors detecting the degree of physical activity of the patient or detecting the respiratory rate and the body position of the patient.
- patient sensor input such as the patient's heart rate
- a sensor for the electrical activity of the patient's heart such as in an electrocardiogram
- motion sensors detecting the degree of physical activity of the patient or detecting the respiratory rate and the body position of the patient.
- the pump rotor and frame are made of biocompatible materials such as stainless steel, metal alloys such as titanium alloys such as Nitinol or other metal alloys, the bearings are made of materials such as ceramics, sapphire or ruby or metal or metal alloys.
- the rotor can be made of magnetic metals or metal alloys.
- the electrical coils of the pump are made of materials such as metal wire, such as copper or gold wire or any suitable metal or metal alloy wire and are encased in a water proof casing made of either a metal, a metal alloy or a polymer.
- the pump also uses polymers to insulate wires and wire connections.
- FIG. 1 is an open pump according to exemplary aspects of the present disclosure
- FIG. 2 is another perspective view of an open pump according to exemplary aspects of the present disclosure
- FIG. 3 is another side view of an open pump according to exemplary aspects of the present disclosure
- FIG. 4 is a top view of an open pump according to exemplary aspects of the present disclosure.
- FIG. 5 is a perspective view of an open pump according to exemplary aspects of the present disclosure.
- FIG. 6 is a side view of the open pump according to exemplary aspects of the present disclosure.
- FIG. 7 is a top view of the open pump according to exemplary aspects of the present disclosure.
- FIG. 8 is a perspective view of an open pump according to exemplary aspects of the present disclosure.
- FIG. 1 is an open pump according to exemplary aspects of the present disclosure.
- the pump includes a frame 101 which holds a central axle 103 onto which a rotor 102 is mounted. Also attached between the central axle 103 and the frame are two electromagnetic coils 104 and 105 , which cause the rotor 102 to turn when energized.
- the coils 104 and 105 are arranged radially or slightly “off-center” within the blood channel.
- a Hall sensor is used or backward electromagnetic pulse sensing (EMP pulse sensing) is used.
- the pump also includes an opening 107 for insertion of one or more magnets that are used to cause the rotor 102 to rotate, and has a power cable 108 attached to the coils 104 , 15 in order to provide power to those coils.
- the open pump does not include a casing, and is instead supported by the frame 101 , thus minimizing resistance to blood flow.
- FIG. 1 also illustrates that the frame 101 holds the central axle 103 in openings that receive a bushing 106 , or similar retention device.
- the bushing 106 may be a pressure fit, and may be machined to have a recess around its outer circumference in order to fit within the opening in the frame 101 .
- the bushing may also include a bearing, bearing assembly, or a pencil-point bearing, in order to allow the central axle 103 to spin freely with minimal resistance.
- other bushing and bearing designs are possible without departing from the scope of the present disclosure.
- FIG. 1 illustrates the central axle 103 held by bushings 106 at either side of the frame 101
- the bushings 106 may be omitted and the central axle 103 may be directly held by the frame 101 without any other structure.
- a cotter pin or similar structure may be used.
- the holes in the frame 101 that hold the central axle 103 may also be “blind” holes that do not extend the entire thickness of the frame material in order to retain the central axle 103 in place.
- blind holes that do not extend the entire thickness of the frame material in order to retain the central axle 103 in place.
- One of ordinary skill would recognize that other ways of rotatably affixing the central axle 103 to the frame 101 are possible without departing from the present disclosure.
- FIG. 2 is a perspective view of an open pump according to exemplary aspects of the present disclosure.
- the rotor is omitted for clarity.
- the frame 201 of FIG. 2 includes recesses in which coils 205 are placed.
- two sets of opposing electromagnetic coils 205 are situated radially in the frame 201 . They can also have a slightly “off-center” configuration to allow rotation of the pump in only one direction.
- the bushings 106 hold the central axle 3 (not shown) on which the rotor may be installed.
- Using a pair of electromagnetic coils allows for timing of the electrical pulses to the coils with back-electromagnetic pulse sensing, thus eliminating the need for a Hall sensor.
- this configuration allows for a more powerful motor, which may be useful due to size constraints required for a minimally invasive placement of the pump.
- This set up with 4 or more magnets facilitates the use of EMP back sensing to time the pump as the pump can be propelled by one pair of magnets while the other pair is set for short periods of time in a sensing mode.
- FIG. 3 is a side view of the open pump of FIG. 2 .
- the rotor, central axle 103 , and bushings 106 that hold the central axle 103 are omitted for clarity.
- the structure of the frame 201 in FIG. 2 includes two members 202 , 203 that each hold two electromagnetic coils and two endplates 204 and 206 that respectively attach to the ends of the two members 202 , 203 .
- the frame 201 may also be made as a single piece without departing from the scope of the present disclosure.
- FIG. 4 is a top view of the open pump of FIGS. 2 and 3 .
- the bushing 106 , endplates 204 , 206 , and one of the members 203 are illustrated.
- the coils 205 are held in place by the member 203 in a recess created for the coils 205 by the side walls of the member 203 . Because the side walls of the member 203 curve around the coils 205 no additional retainer is needed to hold the coils 205 in place.
- additional retainers such as a clamp, screw, etc., may also be used in addition to, or instead of the curved sidewalls of the member 203 in order to hold the coils 250 in place.
- the coils 205 may also be held in place using a resin or adhesive, as one of ordinary skill would recognize.
- the member 202 has substantially the same structure as the member 203 .
- FIG. 5 is a perspective view of an open pump according to exemplary aspects of the present disclosure.
- the pump includes a frame 301 that includes a cylinder 302 which holds a plurality of electromagnetic coils 305 arrange around the interior circumference thereof.
- the cylinder 302 includes two supports 304 that support a beam 303 into which a bushing 308 to hold the central axle of the rotor 306 is placed.
- a similar beam is also affixed to the opposite side of the cylinder 302 .
- the cylinder 302 can be made of a flexible material for minimally invasive implantation, such as an endovascular stent holding rigid support beams 303 and 304 .
- the rotor 306 includes magnets 307 that, in combination with the electromagnetic coils 305 , cause the rotor 306 to spin.
- the rotor can have different shapes than in this schematic drawing, such as in FIG. 1 to optimally propel the blood.
- the rotor can also be made of magnetic material itself this obviating the need for separate magnets.
- the electromagnetic coils 305 are arranged perpendicular or minimally oblique to the rotor 306 and parallel to a flow of blood. Though FIG. 5 illustrates 6 coils 305 , more or fewer coils 305 may be used depending on application as one of ordinary skill would recognize.
- FIG. 6 is a side view of the open pump of FIG. 5 .
- the rotor 306 is suspended above the cylinder 302 and electromagnetic coils 305 such that the overall structure of the pump remains open and present low resistance to blood flow.
- the coils 305 may be held in place via a pressure fit in individual cylinders formed around the circumference of the cylinder 302 , or may be adhered in place with an adhesive or resin.
- the coils 305 may also be mechanically held with a retainer, or fastener, such as a clamp. Other methods and structures for holding the coils 305 in place are also possible without departing from the scope of the present disclosure.
- FIG. 7 is a top view of the pump of FIGS. 5 and 6 .
- This figure illustrates the open design of the pump, which allows blood to flow even when the pump is stopped.
- the figure also illustrates that the bushing 308 that holds the axle 309 of the rotor 306 .
- the bushing 308 may be omitted and the axle 309 may be held in place directly by the frame 301 and a cotter pin at each end of the axle 309 .
- the pump illustrated in FIGS. 5 - 7 may be scaled to fit in a human heart and that the electromagnetic coils, which are oriented perpendicularly to the rotor in the direction of blood flow, can be mounted on a vascular stent or a stent graft (not shown).
- the electromagnetic coils can also be held in position with flexible circular or diagonally oriented metal struts made from a metal, a metal alloy such as Nitinol or a polymer.
- FIG. 8 is a perspective view of an open pump according to exemplary aspects of the present disclosure.
- the pump in FIG. 8 includes a cylinder 401 in which a frame 402 is installed.
- the frame 402 holds the central axle of a rotor 403 .
- a plurality of electromagnetic coils 404 that are arranged at a predetermined angle relative to the blood flow. This predetermined angle may be any angle between 0 and 180 degrees, as one of ordinary skill would recognize.
- the cylinder 401 may be replaced with a stent or a stent graft that holds the pump in place in the heart.
- the frame 402 may also be formed with the cylinder 401 as one piece.
- 401 shows another exemplary rotor configuration with a “double blade rotor”. Other variations are possible without departing from the scope of the present disclosure.
- the pumps may also be made of any material that is compatible with implantation in living tissue, and part or the entire pump may be coated with a conformal coating in order to protect the pump components.
- inventive pump in a failing heart for the sake of clarity.
- inventive pump may be used in other applications in which a pump that presents little resistance to flow when stopped is required. Accordingly, the descriptions herein are merely exemplary and do not limit the scope of the present disclosure. Obviously, numerous modifications and variations of the present invention are possible in light of the above teachings. It is therefore to be understood that within the scope of the appended claims, the invention may be practiced otherwise than as specifically described herein.
Abstract
An implantable pump is configured to be implanted in series with blood flow from a heart. The pump includes a frame configured to be implanted within the natural blood flow of the heart such as a ventricular outflow tract an outlet valve of the heart, and a central axle configured to be affixed within the frame parallel to the blood flow. The pump also includes a rotor attached to the central axle and configured to rotate in order to pump blood, and at least two electromagnetic coils configured to be energized in order to cause the rotor to rotate.
Description
- This application is a continuation of U.S. application Ser. No. 16/526,521, filed Jul. 30, 2019, which claims the benefit of priority of the filing date of provisional application No. 62/711,856, filed Jul. 30, 2018, the entire contents of each are incorporated herein by reference.
- The present disclosure is directed to open electric pumps used to pump fluids. Specifically, the present disclosure describes an open electric pump that may be implanted in a failing heart to assist in the pumping of blood.
- Heart failure patients have failing hearts that do not adequately pump blood through the patient's circulatory system. Therefore, circulatory assist devices have been developed in order to aid a failing heart to pump blood. Such devices can include rotary axial flow pumps, or centrifugal pumps, that have rotors which pumps blood by spinning. These conventional pumps also include casings that surround the rotor with very small tolerances between the rotor and the casing wall. This “closed” design results in severe resistance to blood flow if the motor of the conventional pump stops pumping, which can occur if an associated battery pack becomes drained or if the conventional pump itself malfunctions.
- To maintain circulation if the pump stops pumping, the conventional pump must be used in parallel to the natural blood flow of the heart, usually from the apex of the left ventricle to the ascending or descending aorta. Other parallel pump-configurations from a main pumping chamber or a pre-chamber to the aorta or pulmonary artery are also being used for left or right heart support. This parallel configuration allows the natural heart to eject and support circulation even if the pump is temporarily stopped. Implanting a conventional pump in series with the blood flow from the heart, such as in the left ventricle outflow tract or within an outflow valve of a main pumping chamber, can lead to catastrophic circulatory collapse if the conventional pump stops pumping, such as during a battery exchange, an inadvertent disconnection of the battery, or pump malfunction. This is because the closed design of conventional pumps allows very little blood to pass through them when the pump is stopped.
- Conventional pumps also include coils that generate heat, which is transferred to the surrounding tissue and blood by the casing. This can case the blood and surrounding tissue to warm to the point of causing damage to blood proteins and other cellular blood components, possibly leading to clotting and a thromboembolism.
- Thus, there is a need for a new pump design that is able to be implanted in series with the blood flow of the heart without causing significant resistance to blood flow if the pump stops, and that minimizes trauma to the blood and surrounding tissues and minimizes heat transfer to the surrounding tissues.
- The present disclosure is directed to a pump that has an “open” design to allow placement of the pump in series with blood flow from the heart. The open design of the pump also allows for a larger, more efficient rotor that pumps blood effectively at lower rotor speeds, resulting in less shear forces on the blood and its cellular components and therefore in less trauma. The open design of the pump greatly reduces resistance to blood flow in the event of a pump stoppage, minimizing the risk of circulatory collapse. Thus, the inventive pump described herein may be placed in, for example, the left or right ventricular outflow tract or within the position of an outflow valve of the right or left ventricle without any of the negative effects of conventional pumps.
- The open design further provides for better heat exchange and potentially less blood trauma than conventional pumps due to the larger surface area exposed to the blood. In the pump, a much larger portion of the surface of the electromagnetic coils is in contact with the blood stream that in conventional pumps. This allows for a better heatsink function and less warming of the blood components, and reduces the likelihood of thromboembolic complications. The inventive open pump can also be configured so that endovascular/minimally invasive placement from within the blood stream is possible.
- Specifically, in one aspect of the present disclosure, an implantable pump is configured to be implanted in series with blood flow from a heart. The pump includes a frame configured to be implanted in a ventricular outflow tract of the heart, and a central axle configured to be affixed within the frame parallel to the blood flow. The pump also includes a rotor attached to the central axle and configured to rotate in order to pump blood, and at least two electromagnetic coils configured to be energized in order to cause the rotor to rotate.
- The timing of the electrical pulses to propel the pump rotor are based either on hall sensors or back electromagnetic pulse sensing (back EMP sensing) from the rotating magnets passing the coils. The pump is controlled by an electromechanical or electronic external control unit (not shown in pictures) which has the ability to adjust the pump rotary speed by manual control and also can have automatically adjustable variable pump speed features that adjust the rotary speed based on patient sensor input, such as the patient's heart rate, with a sensor for the electrical activity of the patient's heart (such as in an electrocardiogram) or with motion sensors detecting the degree of physical activity of the patient or detecting the respiratory rate and the body position of the patient.
- The pump rotor and frame are made of biocompatible materials such as stainless steel, metal alloys such as titanium alloys such as Nitinol or other metal alloys, the bearings are made of materials such as ceramics, sapphire or ruby or metal or metal alloys. The rotor can be made of magnetic metals or metal alloys. The electrical coils of the pump are made of materials such as metal wire, such as copper or gold wire or any suitable metal or metal alloy wire and are encased in a water proof casing made of either a metal, a metal alloy or a polymer. The pump also uses polymers to insulate wires and wire connections.
- A more complete appreciation of the invention and many of the attendant advantages thereof will be readily obtained as the same becomes better understood by reference to the following detailed description when considered in connection with the accompanying drawings, wherein:
-
FIG. 1 is an open pump according to exemplary aspects of the present disclosure; -
FIG. 2 is another perspective view of an open pump according to exemplary aspects of the present disclosure; -
FIG. 3 is another side view of an open pump according to exemplary aspects of the present disclosure; -
FIG. 4 is a top view of an open pump according to exemplary aspects of the present disclosure; -
FIG. 5 is a perspective view of an open pump according to exemplary aspects of the present disclosure; -
FIG. 6 is a side view of the open pump according to exemplary aspects of the present disclosure; -
FIG. 7 is a top view of the open pump according to exemplary aspects of the present disclosure; and -
FIG. 8 is a perspective view of an open pump according to exemplary aspects of the present disclosure. - Referring now to the drawings, wherein like reference numerals designate identical or corresponding parts throughout the several views,
FIG. 1 is an open pump according to exemplary aspects of the present disclosure. As illustrated inFIG. 1 , the pump includes aframe 101 which holds acentral axle 103 onto which arotor 102 is mounted. Also attached between thecentral axle 103 and the frame are twoelectromagnetic coils rotor 102 to turn when energized. Thecoils electromagnetic coils opening 107 for insertion of one or more magnets that are used to cause therotor 102 to rotate, and has apower cable 108 attached to thecoils 104, 15 in order to provide power to those coils. The open pump does not include a casing, and is instead supported by theframe 101, thus minimizing resistance to blood flow. -
FIG. 1 also illustrates that theframe 101 holds thecentral axle 103 in openings that receive abushing 106, or similar retention device. Thebushing 106 may be a pressure fit, and may be machined to have a recess around its outer circumference in order to fit within the opening in theframe 101. The bushing may also include a bearing, bearing assembly, or a pencil-point bearing, in order to allow thecentral axle 103 to spin freely with minimal resistance. Of course, other bushing and bearing designs are possible without departing from the scope of the present disclosure. - Though
FIG. 1 illustrates thecentral axle 103 held bybushings 106 at either side of theframe 101, thebushings 106 may be omitted and thecentral axle 103 may be directly held by theframe 101 without any other structure. To prevent thecentral axle 103 from working itself free of theframe 101, a cotter pin or similar structure may be used. The holes in theframe 101 that hold thecentral axle 103 may also be “blind” holes that do not extend the entire thickness of the frame material in order to retain thecentral axle 103 in place. One of ordinary skill would recognize that other ways of rotatably affixing thecentral axle 103 to theframe 101 are possible without departing from the present disclosure. -
FIG. 2 is a perspective view of an open pump according to exemplary aspects of the present disclosure. InFIG. 2 , the rotor is omitted for clarity. Theframe 201 ofFIG. 2 includes recesses in which coils 205 are placed. As can be seen two sets of opposingelectromagnetic coils 205 are situated radially in theframe 201. They can also have a slightly “off-center” configuration to allow rotation of the pump in only one direction. Thebushings 106 hold the central axle 3 (not shown) on which the rotor may be installed. Using a pair of electromagnetic coils allows for timing of the electrical pulses to the coils with back-electromagnetic pulse sensing, thus eliminating the need for a Hall sensor. Also, this configuration allows for a more powerful motor, which may be useful due to size constraints required for a minimally invasive placement of the pump. This set up with 4 or more magnets facilitates the use of EMP back sensing to time the pump as the pump can be propelled by one pair of magnets while the other pair is set for short periods of time in a sensing mode. -
FIG. 3 is a side view of the open pump ofFIG. 2 . InFIG. 3 the rotor,central axle 103, andbushings 106 that hold thecentral axle 103 are omitted for clarity. As can be seen, the structure of theframe 201 inFIG. 2 includes twomembers endplates members frame 201 may also be made as a single piece without departing from the scope of the present disclosure. -
FIG. 4 is a top view of the open pump ofFIGS. 2 and 3 . InFIG. 4 thebushing 106,endplates members 203 are illustrated. As can be seen from this figure, thecoils 205 are held in place by themember 203 in a recess created for thecoils 205 by the side walls of themember 203. Because the side walls of themember 203 curve around thecoils 205 no additional retainer is needed to hold thecoils 205 in place. However, additional retainers such as a clamp, screw, etc., may also be used in addition to, or instead of the curved sidewalls of themember 203 in order to hold the coils 250 in place. Thecoils 205 may also be held in place using a resin or adhesive, as one of ordinary skill would recognize. Though not illustrated, themember 202 has substantially the same structure as themember 203. -
FIG. 5 is a perspective view of an open pump according to exemplary aspects of the present disclosure. The pump includes aframe 301 that includes acylinder 302 which holds a plurality ofelectromagnetic coils 305 arrange around the interior circumference thereof. Thecylinder 302 includes twosupports 304 that support abeam 303 into which abushing 308 to hold the central axle of therotor 306 is placed. A similar beam is also affixed to the opposite side of thecylinder 302. Thecylinder 302 can be made of a flexible material for minimally invasive implantation, such as an endovascular stent holdingrigid support beams rotor 306 includesmagnets 307 that, in combination with theelectromagnetic coils 305, cause therotor 306 to spin. The rotor can have different shapes than in this schematic drawing, such as inFIG. 1 to optimally propel the blood. The rotor can also be made of magnetic material itself this obviating the need for separate magnets. As can be seen, theelectromagnetic coils 305 are arranged perpendicular or minimally oblique to therotor 306 and parallel to a flow of blood. ThoughFIG. 5 illustrates 6coils 305, more orfewer coils 305 may be used depending on application as one of ordinary skill would recognize. -
FIG. 6 is a side view of the open pump ofFIG. 5 . As can be seen from this view, therotor 306 is suspended above thecylinder 302 andelectromagnetic coils 305 such that the overall structure of the pump remains open and present low resistance to blood flow. Thecoils 305 may be held in place via a pressure fit in individual cylinders formed around the circumference of thecylinder 302, or may be adhered in place with an adhesive or resin. Thecoils 305 may also be mechanically held with a retainer, or fastener, such as a clamp. Other methods and structures for holding thecoils 305 in place are also possible without departing from the scope of the present disclosure. -
FIG. 7 is a top view of the pump ofFIGS. 5 and 6 . This figure illustrates the open design of the pump, which allows blood to flow even when the pump is stopped. The figure also illustrates that thebushing 308 that holds the axle 309 of therotor 306. As can be appreciated, thebushing 308 may be omitted and the axle 309 may be held in place directly by theframe 301 and a cotter pin at each end of the axle 309. - The pump illustrated in
FIGS. 5-7 may be scaled to fit in a human heart and that the electromagnetic coils, which are oriented perpendicularly to the rotor in the direction of blood flow, can be mounted on a vascular stent or a stent graft (not shown). The electromagnetic coils can also be held in position with flexible circular or diagonally oriented metal struts made from a metal, a metal alloy such as Nitinol or a polymer. -
FIG. 8 is a perspective view of an open pump according to exemplary aspects of the present disclosure. The pump inFIG. 8 includes acylinder 401 in which aframe 402 is installed. Theframe 402 holds the central axle of arotor 403. Along the interior circumference of thecylinder 401 are a plurality ofelectromagnetic coils 404 that are arranged at a predetermined angle relative to the blood flow. This predetermined angle may be any angle between 0 and 180 degrees, as one of ordinary skill would recognize. As can be appreciated, thecylinder 401 may be replaced with a stent or a stent graft that holds the pump in place in the heart. Theframe 402 may also be formed with thecylinder 401 as one piece. 401 shows another exemplary rotor configuration with a “double blade rotor”. Other variations are possible without departing from the scope of the present disclosure. - Though the pumps described above have been described individually for the sake of clarity, one of ordinary skill would recognize that the different features described for one pump may be combined with the features of the other pumps without limitation.
- Moreover, to the extent that the figures and descriptions herein identify a specific number of electromagnetic coils, such number is merely exemplary since for each pump more, weaker coils may be used, or fewer, stronger coils may be used. The pumps may also be made of any material that is compatible with implantation in living tissue, and part or the entire pump may be coated with a conformal coating in order to protect the pump components.
- The descriptions herein have been made with reference to implantation of the inventive pump in a failing heart for the sake of clarity. However, the inventive pump may be used in other applications in which a pump that presents little resistance to flow when stopped is required. Accordingly, the descriptions herein are merely exemplary and do not limit the scope of the present disclosure. Obviously, numerous modifications and variations of the present invention are possible in light of the above teachings. It is therefore to be understood that within the scope of the appended claims, the invention may be practiced otherwise than as specifically described herein.
Claims (9)
1. (canceled)
2. An implantable pump configured to be implanted in series with blood flow from a heart, the pump comprising:
a frame configured to be implanted in a natural blood path of blood in the heart;
a central axle disposed within the frame and held in a position parallel to blood flow by the frame;
a rotor attached to the central axle and configured to rotate with the central axle to pump blood;
permanent magnets disposed at ends of the rotor;
a plurality of electromagnetic coils disposed within the frame and overlapping the ends of the rotor when the implantable pump is viewed from a direction parallel to the blood flow, the electromagnetic coils being configured to, in conjunction with the permanent magnets, cause the rotor to rotate.
3. The implantable pump according to claim 2 , wherein the frame includes a cylindrical portion, and the plurality of electromagnetic coils are attached to the cylindrical portion.
4. The implantable pump according to claim 3 , wherein the frame further includes:
at least one support beam configured to hold the axle in place, and
a plurality of support members configured to attach the support beam to the cylindrical portion.
5. The implantable pump according to claim 4 , wherein the at least one support beam includes a bushing into which an end of the axle is inserted.
6. The implantable pump according to claim 2 , wherein the plurality of electromagnetic coils are evenly distributed around the cylindrical portion.
7. The implantable pump according to claim 6 , wherein the plurality of electromagnetic coils include six electromagnetic coils.
8. The implantable pump according to claim 2 , wherein axes of the electromagnetic coils are parallel to the blood flow.
9. The implantable pump according to claim 2 , wherein the plurality of magnetic coils are configured to generate an axial magnetic field along a main axis of the implantable pump.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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US18/368,045 US20240001102A1 (en) | 2018-07-30 | 2023-09-14 | Open electric pump |
Applications Claiming Priority (3)
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US201862711856P | 2018-07-30 | 2018-07-30 | |
US16/526,521 US11793993B2 (en) | 2018-07-30 | 2019-07-30 | Open electric pump |
US18/368,045 US20240001102A1 (en) | 2018-07-30 | 2023-09-14 | Open electric pump |
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US16/526,521 Continuation US11793993B2 (en) | 2018-07-30 | 2019-07-30 | Open electric pump |
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US20240001102A1 true US20240001102A1 (en) | 2024-01-04 |
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US16/526,521 Active US11793993B2 (en) | 2018-07-30 | 2019-07-30 | Open electric pump |
US18/368,045 Pending US20240001102A1 (en) | 2018-07-30 | 2023-09-14 | Open electric pump |
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US16/526,521 Active US11793993B2 (en) | 2018-07-30 | 2019-07-30 | Open electric pump |
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US (2) | US11793993B2 (en) |
EP (1) | EP3829674A4 (en) |
JP (1) | JP2021532958A (en) |
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CN (1) | CN113226439A (en) |
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CA (1) | CA3108320A1 (en) |
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US5092879A (en) * | 1988-02-17 | 1992-03-03 | Jarvik Robert K | Intraventricular artificial hearts and methods of their surgical implantation and use |
US5613935A (en) * | 1994-12-16 | 1997-03-25 | Jarvik; Robert | High reliability cardiac assist system |
CA2237203C (en) * | 1996-09-10 | 2007-09-18 | Sulzer Electronics Ag | Rotary pump and method for operation thereof |
US6201329B1 (en) * | 1997-10-27 | 2001-03-13 | Mohawk Innovative Technology, Inc. | Pump having magnetic bearing for pumping blood and the like |
US7798952B2 (en) * | 2003-10-09 | 2010-09-21 | Thoratec Corporation | Axial flow blood pump |
EP1789111A2 (en) * | 2004-07-19 | 2007-05-30 | VASCOR, Inc. | Devices, systems and methods for assisting blood flow |
DE102005045597B4 (en) * | 2005-09-23 | 2017-05-18 | Siemens Healthcare Gmbh | In the human or animal body implantable pumping device and pumping device comprising such a pumping device |
US8690749B1 (en) * | 2009-11-02 | 2014-04-08 | Anthony Nunez | Wireless compressible heart pump |
US8734508B2 (en) * | 2009-12-21 | 2014-05-27 | Boston Scientific Scimed, Inc. | Systems and methods for making and using percutaneously-delivered pumping systems for providing hemodynamic support |
KR102025959B1 (en) * | 2011-11-28 | 2019-09-26 | 미-바드, 아이엔씨. | Ventricular assist device and method |
EP2692369B1 (en) * | 2012-07-31 | 2015-04-15 | Rheinisch-Westfälische Technische Hochschule Aachen | Axial flow blood pump device |
AU2013308931A1 (en) | 2012-08-27 | 2015-04-02 | Ecotech Marine, Llc | Electromagnetic circulation pump |
JP2014068460A (en) * | 2012-09-26 | 2014-04-17 | Seiko Epson Corp | Electromechanical device, rotor used in electromechanical device, and movable body and robot using electromechanical device |
DE102013208038B4 (en) * | 2013-05-02 | 2016-09-08 | Michael Siegenthaler | Catheter-based cardiac assist system |
EP3110468B1 (en) * | 2014-02-25 | 2021-11-03 | Kushwaha, Sudhir | Ventricular assist device and method |
DE102014012423A1 (en) * | 2014-08-20 | 2016-02-25 | Fresenius Medical Care Deutschland Gmbh | Dialysis machine with the ability to determine a predialytic property in the blood of a dialysis patient |
US10371152B2 (en) * | 2015-02-12 | 2019-08-06 | Tc1 Llc | Alternating pump gaps |
WO2017015210A1 (en) * | 2015-07-20 | 2017-01-26 | Thoratec Corporation | Strain gauge for flow estimation |
US10166319B2 (en) * | 2016-04-11 | 2019-01-01 | CorWave SA | Implantable pump system having a coaxial ventricular cannula |
US9945418B1 (en) * | 2016-07-31 | 2018-04-17 | Rotor Bearings Solutions International, LLC | Thrust and radial magnetic bearings using combined electromagnetic and permanent magnetic flux paths |
US20180326132A1 (en) * | 2017-05-12 | 2018-11-15 | Edwards Lifesciences Corporation | Pump for treating congestive heart failure |
US11679250B2 (en) * | 2019-06-28 | 2023-06-20 | Theodosios Alexander | Removable mechanical circulatory support for short term use |
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2019
- 2019-07-30 AU AU2019315428A patent/AU2019315428A1/en active Pending
- 2019-07-30 EP EP19843389.8A patent/EP3829674A4/en active Pending
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US11793993B2 (en) | 2023-10-24 |
JP2021532958A (en) | 2021-12-02 |
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WO2020028380A1 (en) | 2020-02-06 |
CA3108320A1 (en) | 2020-02-06 |
US20200030508A1 (en) | 2020-01-30 |
EP3829674A4 (en) | 2022-07-13 |
CN113226439A (en) | 2021-08-06 |
EP3829674A1 (en) | 2021-06-09 |
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