US20230416747A1

US20230416747A1 - Safe harbor loci

Info

Publication number: US20230416747A1
Application number: US18/453,801
Authority: US
Inventors: Xinying Zheng; Brendan Galvin; Somya Khare; Aaron Cooper; Michelle Nguyen; Anzhi Yao
Original assignee: Arsenal Biosciences Inc
Current assignee: Arsenal Biosciences Inc
Priority date: 2020-10-26
Filing date: 2023-08-22
Publication date: 2023-12-28
Also published as: US20220127616A1; US20220315928A1; US11332744B1; US11761004B2

Abstract

Provided herein are safe harbor loci and methods for identifying and using safe harbor loci to engineer cells to express transgenes. The safe harbor loci exhibit increased transgene knock-in efficiency and allow for increased, stable expression of transgenes in engineered cells. Guide ribonucleic acids (gRNAs) may be used for insertion of transgenes in the safe harbor loci.

Description

CROSS REFERENCE TO RELATED APPLICATIONS

This application is a divisional of U.S. application Ser. No. 17/716,816 filed Apr. 8, 2022, allowed, which is a divisional of U.S. application Ser. No. 17/239,484 filed Apr. 23, 2021, allowed, which claims priority to and the benefit of U.S. Provisional Patent Application No. 63/141,926, filed on Jan. 26, 2021, and U.S. Provisional Patent Application No. 63/105,834, filed on Oct. 26, 2020, the entire contents of which are incorporated by reference herein for all purposes.

SEQUENCE LISTING

The instant application contains a Sequence Listing which will be submitted via Patent Center and is hereby incorporated by reference in its entirety. Said XML copy, created on Aug. 29, 2023, is named ANB-203D2_SL.xml and is 845,305 bytes in size.

BACKGROUND

Cancer continues to present a significant clinical burdSen despite the substantial research efforts and scientific advances in cancer therapies. Blood and bone marrow cancers are frequently diagnosed cancer types, including multiple myelomas, leukemia, and lymphomas. Current treatment options for these cancers are not effective for all patients and/or can have substantial adverse side effects. Other types of cancer also remain challenging to treat using existing therapeutic options. Cancer immunotherapies are a promising solution because they can be highly specific, allowing for increased therapeutic effectiveness and the mitigation of side effects.
Genetically engineered immune cell therapy is a growing field with promising applications for the treatment of diseases including, but not limited to, cancer. Through the alteration of coding and/or non-coding genomic regions, researchers are identifying transgenes and insertion sites within cells that facilitate, for example, enhanced cell function, arrest cell growth, induced cell death, and tumor size/volume reduction. The identification of safe harbor sites (SHS) has improved outcomes of genome-engineering therapies. Well known SHS include the AAVS1 adeno-associated virus insertion site on chromosome 19, the human homolog of the murine Rosa26 locus, and the CCR5 chemokine receptor gene—the absence of which confers HIV resistance. (See, for example, Pellenz et al., 2018, the relevant disclosures of which are herein incorporated by reference). However, there is still a need for improved guidelines for gene editing therapies and additional SHS to address challenges such as poor knock-in (KI) efficiency, insertional oncogenesis, unstable and/or anomalous expression of transgenes and/or adjacent genes, etc.

SUMMARY

The present disclosure is directed, inter alia, to safe harbor loci that exhibit high knock-in efficiency and stable expression of their transgenes. These safe harbor loci can be used to alter T cells for immunotherapy. These safe harbor loci are useful for the treatment of various diseases, including cancer.
In one aspect, the present disclosure provides an engineered cell, comprising at least one sequence encoding a transgene, wherein the at least one sequence is inserted within a safe harbor locus, the safe harbor locus is at any one or more of the sgRNA target loci provided in Table 4; and wherein expression of the at least one sequence encoding the transgene is operatively linked to an endogenous promoter. In another aspect, the present disclosure provides an engineered cell, comprising at least one sequence encoding a transgene, wherein the at least one sequence is inserted within a safe harbor locus, the safe harbor locus is at any one or more of the sgRNA target loci provided in Table 4; and wherein expression of the at least one sequence encoding the transgene is operatively linked to an exogenous promoter.
In some embodiments, the target locus is selected from: chr10:33130000-33140000, chr10:72290000-72300000, chr11:128340000-128350000, chr11:65425000-65427000 (NEAT1), chr15:92830000-92840000, chr16:11220000-11230000, chr2:87460000-87470000, chr3:186510000-186520000, chr3:59450000-59460000, chr8:127980000-128000000, and chr9:7970000-7980000. In some embodiments, the target locus is selected from: chr10:72290000-72300000, chr11:128340000-128350000, chr15:92830000-92840000, and chr16:11220000-11230000. In some embodiments, the target locus is chr11:128340000-128350000. In some embodiments, the target locus is chr15:92830000-92840000. In some embodiments, the target locus is a gene selected from: APRT, B2M, CAPNS1, CBLB, CD2, CD3E, CD3G, CD5, EDF1, FTL, PTEN, PTPN2, PTPN6, PTPRC, PTPRCAP, RPS23, RTRAF, SERF2, SLC38A1, SMAD2, SOCS1, SRP14, SRSF9, SUB1, TET2, TIGIT, TRAC, and TRIM28.
In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS88, GS89, GS90, GS91, GS92, GS93, GS94, GS95, GS96, GS97, GS98, GS99, GS100, GS101, GS102, GS103, GS104, GS105, GS106, GS107, GS108, GS109, GS110, GS111, GS112, GS113, GS114, GS115, GS116, GS117, GS118, GS119, GS120. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS91, GS92, GS93, GS94, GS95, GS96, GS100, GS101, GS102, GS103, GS104, and GS105. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS103, GS104, and GS105. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS94, GS95, and GS96. In some embodiments, the safe harbor locus is the GS94 integration site in Table 4. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS100, GS101, and GS102. In some embodiments, the safe harbor locus is the GS102 integration site in Table 4. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS91, GS92, and GS93.
In some embodiments, the exogenous promoter is an EF1a promoter. In some embodiments, the engineered cell is a stem cell, a human cell, a primary cell, an hematopoietic cell, an adaptive immune cell, an innate immune cell, a T cell or a T cell progenitor. In some embodiments, the transgene encodes a recombinant protein, optionally a therapeutic agent. In some embodiments, the transgene encodes a chimeric antigen receptor (CAR).
In another aspect, the present disclosure provides a composition comprising the engineered cell as described herein and a pharmaceutical excipient.
In another aspect, the present disclosure provides a guide ribonucleic acids (gRNA) for editing a cell at a safe harbor locus, wherein gRNA comprises any one of the sgRNA sequences in Table 4.
In some embodiments, the gRNA comprises any one of SEQ ID NOS:1-120. In some embodiments, the gRNA comprises any one of SEQ ID NOS: 91-96 and 100-105. In some embodiments, the gRNA comprises SEQ ID NO:94 or SEQ ID NO:102. In some embodiments, the gRNA comprises SEQ ID NO:94. In some embodiments, the gRNA comprises SEQ ID NO:102. In some embodiments, the cell is a stem cell, a human cell, a primary cell, an hematopoietic cell, an adaptive immune cell, an innate immune cell, a T cell or a T cell progenitor.
In another aspect, the present disclosure provides a method of editing a cell having chromosomal DNA, comprising inserting at least one sequence encoding a transgene within a safe harbor locus in the chromosomal DNA of the cell, wherein the safe harbor locus is any one or more of the sgRNA target loci provided in Table 4.
In some embodiments, the target locus is selected from: chr10:33130000-33140000, chr10:72290000-72300000, chr11:128340000-128350000, chr11:65425000-65427000 (NEAT1), chr15:92830000-92840000, chr16:11220000-11230000, chr2:87460000-87470000, chr3:186510000-186520000, chr3:59450000-59460000, chr8:127980000-128000000, and chr9:7970000-7980000. In some embodiments, the target locus is selected from: chr10:72290000-72300000, chr11:128340000-128350000, chr15:92830000-92840000, and chr16:11220000-11230000. In some embodiments, the target locus is chr11:128340000-128350000. In some embodiments, the target locus is chr15:92830000-92840000. In some embodiments, the target locus is a gene selected from: APRT, B2M, CAPNS1, CBLB, CD2, CD3E, CD3G, CD5, EDF1, FTL, PTEN, PTPN2, PTPN6, PTPRC, PTPRCAP, RPS23, RTRAF, SERF2, SLC38A1, SMAD2, SOCS1, SRP14, SRSF9, SUB1, TET2, TIGIT, TRAC, and TRIM28.
In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS88, GS89, GS90, GS91, GS92, GS93, GS94, GS95, GS96, GS97, GS98, GS99, GS100, GS101, GS102, GS103, GS104, GS105, GS106, GS107, GS108, GS109, GS110, GS111, GS112, GS113, GS114, GS115, GS116, GS117, GS118, GS119, GS120. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS91, GS92, GS93, GS94, GS95, GS96, GS100, GS101, GS102, GS103, GS104, and GS105. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS103, GS104, and GS105. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS94, GS95, and GS96. In some embodiments, the safe harbor locus is the GS94 integration site in Table 4. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS100, GS101, and GS102. In some embodiments, the safe harbor locus is the GS102 integration site in Table 4. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS91, GS92, and GS93.
In some embodiments, the transgene encodes a recombinant protein, optionally a therapeutic agent. In some embodiments, the transgene encodes a chimeric antigen receptor (CAR). In some embodiments, the at least one sequence comprises an exogenous promoter and the exogenous promoter is operably linked to the transgene. In some embodiments, the exogenous promoter is an EF1a promoter. In some embodiments, the cell is a stem cell, a human cell, a primary cell, an hematopoietic cell, an adaptive immune cell, an innate immune cell, a T cell or T cell progenitor. In some embodiments, the at least one sequence is inserted using a homology-directed repair. In some embodiments, the at least one sequence is inserted using a homology independent targeted insertion. In some embodiments, the at least one sequence is inserted using one or more guide ribonucleic acids (gRNAs) and one or more Cas9 endonucleases.
In some embodiments, the one or more gRNAs comprises any one of SEQ ID NOS: 1-120. In some embodiments, the one or more gRNAs comprises any one of SEQ ID NOS: 91-96 and 100-105. In some embodiments, the gRNA comprises SEQ ID NO:94 or SEQ ID NO:102. In some embodiments, the gRNA comprises SEQ ID NO:94. In some embodiments, the gRNA comprises SEQ ID NO:102.
In another aspect, the present disclosure provides a method of editing a T cell, comprising contacting a T cell with one or more guide ribonucleic acids (gRNAs), at least one sequence encoding a transgene, and one or more Cas9 endonucleases, wherein the one or more gRNAs and Cas9 endonucleases facilitate the insertion of the at least one sequence into chromosomal DNA within a safe harbor locus, wherein the safe harbor locus is selected from any one or more of the sgRNA target loci in Table 4.
In some embodiments, the one or more gRNAs comprises a sequence selected from any one of the sgRNA sequences in Table 4. In some embodiments, the one or more gRNAs comprises any one of SEQ ID NOS: 1-120. In some embodiments, the one or more gRNAs comprises any one of SEQ ID NOS: 91-96 and 100-105. In some embodiments, the gRNA comprises SEQ ID NO:94 or SEQ ID NO:102. In some embodiments, the gRNA comprises SEQ ID NO:94. In some embodiments, the gRNA comprises SEQ ID NO:102.
In some embodiments, the target locus is selected from: chr10:33130000-33140000, chr10:72290000-72300000, chr11:128340000-128350000, chr11:65425000-65427000 (NEAT1), chr15:92830000-92840000, chr16:11220000-11230000, chr2:87460000-87470000, chr3:186510000-186520000, chr3:59450000-59460000, chr8:127980000-128000000, and chr9:7970000-7980000. In some embodiments, the target locus is selected from: chr10:72290000-72300000, chr11:128340000-128350000, chr15:92830000-92840000, and chr16:11220000-11230000. In some embodiments, the target locus is chr11:128340000-128350000. In some embodiments, the target locus is chr15:92830000-92840000. In some embodiments, the target locus is a gene selected from: APRT, B2M, CAPNS1, CBLB, CD2, CD3E, CD3G, CD5, EDF1, FTL, PTEN, PTPN2, PTPN6, PTPRC, PTPRCAP, RPS23, RTRAF, SERF2, SLC38A1, SMAD2, SOCS1, SRP14, SRSF9, SUB1, TET2, TIGIT, TRAC, and TRIM28.
In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS88, GS89, GS90, GS91, GS92, GS93, GS94, GS95, GS96, GS97, GS98, GS99, GS100, GS101, GS102, GS103, GS104, GS105, GS106, GS107, GS108, GS109, GS110, GS111, GS112, GS113, GS114, GS115, GS116, GS117, GS118, GS119, GS120. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS91, GS92, GS93, GS94, GS95, GS96, GS100, GS101, GS102, GS103, GS104, and GS105. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS103, GS104, and GS105. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS94, GS95, and GS96. In some embodiments, the safe harbor locus is the GS94 integration site in Table 4. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS100, GS101, and GS102. In some embodiments, the safe harbor locus is the GS102 integration site in Table 4. In some embodiments, the safe harbor locus is selected from any one of the integration sites in Table 4 designated: GS91, GS92, and GS93
In another aspect, the present disclosure provides an ex vivo method of obtaining an engineered cell or population thereof, comprising (a) obtaining a cell; and (b) genetically modifying the cell by inserting at least one sequence encoding a transgene within a safe harbor locus, wherein the safe harbor locus is selected from any one of the sgRNA target loci in Table 4.
In some embodiments, obtaining the cell comprises: (i) collecting a tissue sample from a subject, (ii) isolating the cells from the tissue samples, and (iii) culturing the cells in vitro. In some embodiments, the tissue sample is a blood sample. In some embodiments, the cell is a stem cell, a human cell, a primary cell, an hematopoietic cell, an adaptive immune cell, an innate immune cell, a T cell or T cell precursor. In some embodiments, the at least one sequence is inserted using a homology-directed repair. In some embodiments, the at least one sequence is inserted using a homology independent targeted insertion.
In some embodiments, the genetically modifying in step (b) comprises contacting the cell with one or more guide ribonucleic acids (gRNAs), the at least one sequence, and one or more Cas9 endonucleases, wherein the one or more gRNAs and Cas9 endonucleases facilitate the insertion of the at least one sequence into chromosomal DNA within the safe harbor locus. In some embodiments, the one or more gRNAs comprises a sequence selected from any one of the sgRNA sequences in Table 4.
In some embodiments, the transgene encodes a recombinant protein, optionally a therapeutic agent. In some embodiments, the transgene encodes a chimeric antigen receptor (CAR). In some embodiments, the at least one sequence comprises an exogenous promoter and the exogenous promoter is operably linked to the transgene. In some embodiments, the exogenous promoter is an EF1a promoter.
In yet another aspect, the present disclosure provides a method of treating a subject having or at risk of having a disease, comprising administering to the subject an effective amount of an engineered cell as described herein, a population thereof, or a composition as described herein. In some embodiments, the cell, the population thereof, or the composition is administered to the subject by infusion.
In yet another aspect, the present disclosure provides a method of treating a subject having or at risk of having a disease, comprising (a) conducting any one of the methods described supra; and (b) administering to the subject an effective amount of a composition comprising the cell or a population thereof. In some embodiments, the composition is administered to the subject by infusion. In some embodiments, the disease is cancer. In some embodiments, the disease is blood cancer.
In another aspect, the present disclosure provides a method of identifying a safe harbor locus, comprising: (a) identifying genes or non-coding regions in a chromosome that are above a threshold level for expression across developmental cell states and/or a threshold level for accessibility of chromatin; (b) generating a linear model that correlates the gene or non-coding region from step (a) with knock-in (KI) efficiency and estimates the KI efficiency of any gene or coding region on the chromosome; and (c) selecting the safe harbor locus based on threshold parameters; wherein the safe harbor locus is selected for insertion of at least one sequence encoding a transgene within a cell.
In some embodiments, the threshold parameters include one or more of: stable expression of a transgene, knockout of the gene confers benefit to the function of the cell, no known function within the cell, stable transgene expression in vitro with or without CD3/CD28 stimulation, negligible off-target cleavage as detected by iGuide-Seq or CRISPR-Seq, less off-target cleavage relative to other loci as detected by iGuide-Seq or CRISPR-Seq, negligible transgene-independent cytotoxicity, negligible transgene-independent cytokine expression, negligible transgene-independent chimeric antigen receptor expression, negligible deregulation or silencing of nearby genes, and positioned outside of a cancer-related gene. In some embodiments, the stable expression of a transgene at the safe harbor locus is less than or equal to 2-fold expression change over the course of at least 1, 2, 3, 4, 5, 6, or 7 days, and wherein expression change is measured by mean fluorescence intensity of a reporter gene encoded by the at least one sequence. In some embodiments, the accessibility of chromatin is measured using an assay for transposase-accessible chromatin using sequencing (ATAC-seq). In some embodiments, the level of expression across developmental cell states is measured using RNA sequencing (RNA-seq).
In some embodiments, the cell is a stem cell, a human cell, a primary cell, an hematopoietic cell, an adaptive immune cell, an innate immune cell, a T cell or T cell precursor. In some embodiments, the linear model has a coefficient of determination (R²value) of at least 30%.
In yet another aspect, the present disclosure provides an engineered cell, composition, gRNA or method as described herein, wherein insertion within the safe harbor locus increase cell cytotoxicity of diseased cells.
In yet another aspect, the present disclosure provides an engineered cell, composition, gRNA or method as described herein, wherein knock-in efficiency at the safe harbor locus is increased relative to other locations along the chromosome.

BRIEF DESCRIPTION OF THE DRAWINGS

These and other features, aspects, and advantages of the present invention will become better understood with regard to the following description, and accompanying drawings, where:

FIG. 1 includes a schematic depicting the methodology used to identify safe harbor loci in the present disclosure, in some embodiments.

FIGS. 2A-2C include schematic depicting 3 top safe harbor loci known in the art: AAVS1 (FIG. 2A), CCR5 (FIG. 2B), and Rosa26 (FIG. 2C). The figures were retrieved from Sadelain, M., et al. (2012). Safe harbours for the integration of new DNA in the human genome. Nature reviews Cancer, 12(1), 51-58, the relevant disclosures of which are herein incorporated by reference in their entirety.

FIG. 3 includes a schematic outlining the data provided in Roth, T. L., et al. 2019. Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits. bioRxiv, 604561, the relevant disclosures of which are herein incorporated by reference in their entirety.

FIGS. 4A-4B include heatmaps with samples clustered based on activation status and cell type, generated with processed RNA-seq data. FIG. 4A includes a heatmap of samples generated with processed RNA-seq data. FIG. 4B includes a heatmap sample generated with processed RNA-seq data, showing the clustering of ˜20 k genes.

FIGS. 5A-5B include plots generated using processed RNA-seq data. FIG. 5A includes a plot showing direct correlation between transcript expression data from Roth, T. L., et al. 2019 and transcript expression data generated by the inventors of the present disclosure. FIG. 5B includes a heatmap showing clusters of the top 10% expressed genes.

FIG. 6 includes a heatmap of samples generated with processed ATAC-seq data.

FIGS. 7A-7B includes plots depicting the signal enrichment at transcription start sites (TSS) (FIG. 7A) and peak size distribution (FIG. 7B), generated with processed ATAC-seq data for coding regions.

FIG. 8 includes a plot depicting the open chromatin regions around the TRAC locus.

FIG. 9 includes a plot depicting KI (knock-in) efficiency for coding regions/genes with GFP as a reporter.

FIG. 10 includes a plot depicting KI efficiency for coding regions/genes with tNGFR as a reporter.

FIG. 11 includes plots showing scaled KI efficiency for 90 genes vs d2 (day-2) RNA-seq data, d4 (day-4) RNA-seq data and ATAC-seq data, utilized for the predictive linear model.

FIG. 12 includes a plot showing chromatin accessibility for a top candidate non-coding region, measured using ATAQ sequencing.

FIG. 13A includes plots showing the cell counts for GFP controls used for the evaluation of candidate KI loci. FIG. 13B includes pmax (GFP_high) readings for GFP controls used for the evaluation of candidate KI loci.

FIG. 14A includes plots showing the maximum episomal GFP expression (GFP_high) readings for non-targeting controls. FIG. 14B includes the cell count for non-targeting controls from

donors

1, 2, and 3.

FIG. 15 includes the cell count and maximum GFP expression (GFP_high) readings for WT controls.

FIG. 16 includes plots showing the cell count and maximum GFP expression (GFP_high) readings when using sgRNA5, which targets a B2M safe harbor locus, and the construct expression was driven by an endogenous promoter.

FIG. 17 includes plots showing the cell count and maximum GFP expression (GFP_high) readings when using sgRNA5, which targets a B2M safe harbor locus, and the construct expression was driven by an EF1a promoter.

FIG. 18 includes plots showing the cell count and maximum GFP expression (GFP_high) readings when using sgRNA79 to target a TRAC safe harbor locus, and the construct expression was driven by an endogenous promoter.

FIG. 19 includes plots showing the cell count and maximum GFP expression (GFP_high) readings when using sgRNA79, which targets a TRAC safe harbor locus, and the construct expression was driven by an exogenous promoter.

FIG. 20 includes plots showing TCR (T cell receptor) vs. GFP among all donors and time points when using sgRNA79, and the construct is driven by an endogenous promoter.

FIG. 21 includes plots showing TCR vs. GFP among all donors and time points when using sgRNA79 and the construct is driven by an exogenous promoter.

FIG. 22 includes plots showing the cell count and maximum GFP expression (GFP_high) readings when using sgRNA83, which targets a TRAC safe harbor locus, and the construct expression was driven by an endogenous promoter.

FIG. 23 includes plots showing the cell count and maximum GFP expression (GFP_high) readings when using sgRNA83, which targets a TRAC safe harbor locus, and the construct expression was driven by an exogenous promoter.

FIG. 24 includes plots showing TCR vs. GFP among all donors and time points when using sgRNA83 and the construct is driven by an endogenous promoter.

FIG. 25 includes plots showing TCR vs. GFP among all donors and time points when using sgRNA83 and the construct is driven by an exogenous promoter.

FIG. 26 includes plots illustrating potential sources of variation (e.g., edge effects and electroporation errors) observed between replicates and donors.

FIG. 27 includes plots illustrating potential sources of variation observed between replicates and donors, e.g., relating to inherent differences between donors.

FIG. 28 includes plots illustrating potential sources of variation observed between replicates and donors, e.g., relating to gating errors.

FIG. 29 includes plots showing the GFP mean fluorescence intensity (GFP MFI) and KI efficiency for top KI loci evaluated with endogenous promoters.

FIG. 30 includes plots showing the GFP mean fluorescence intensity (GFP MFI) and KI efficiency for top KI loci evaluated with the EF1a promoter.

FIGS. 31A-31C include plots showing all the significant KI loci (top KI loci) as evaluated with endogenous and EF1a promoters. FIG. 31A includes a plot showing that the expression from the EF1a promoter was approximately 10 times higher than expression from an endogenous promoter. FIG. 31B shows the top KI loci ranked by GFP MFI at week 3. FIG. 31C shows the top integration loci ranked by GFP MFI (at

weeks

3 and 4; donors 1-3).

FIG. 32A includes a plot showing some target loci and their measured transgene expression levels. FIG. 32B includes plots showing the transgene (Prime Receptor (PrimeR)) and TCR expression for the control and insertion at GS94, GS102 and TRAC loci.

FIG. 33A includes a plot showing the PrimeR levels measured for the indicated integration sites. FIG. 33B includes a schematic showing the GS94 integration site on Chromosome 11.

FIG. 34A includes plots showing CAR induction and primeR expression of engineered T cells after 48 hours of coculturing with K562-CD19 cells. FIG. 34B includes plots showing the cytotoxity and cytokine secretion levels for engineered T cells 48 hours of coculturing with K562-CD19/MSLN cells.

FIG. 35A includes a schematic showing the experimental overview for evaluating the effect of integration site on cytotoxicity. FIG. 35B includes plots showing the measured cytotoxicity for engineered T cells cocultured for 48 hours with the K562 CD19+/MSLN+ or K562 CD19−/MSLN+ cells.

FIG. 36A includes a schematic showing the experimental overview for evaluating the effect of integration site on cytokine secretion. FIG. 36B includes plots showing the measured cytokine levels for engineered T cells cocultured for 48 hours with K562 CD19+/MSLN+ cells.

FIG. 37 includes a schematic showing the in vitro experiment conducted to determin the effect of integration site on primeR-independent CAR expression. “Flow” refers to flow cytometry and “restim” refers to repetitive CD3/CD28 stimulation of the engineered T cells. “EP” refers to electroporation.

FIGS. 38A and 38B include plots showing the stability of PrimeR expression over time when using the indicated integration sites. “Flow” refers to flow cytometry and “restim” refers to repetitive CD3/CD28 stimualation of the engineered T cells. “EP” refers to electroporation. In FIG. 38B, the PrimeR expression is normalized to the expression from using the TRAC integration site.

FIG. 39A includes a schematic showing the iGuide-Seq assay technique. FIG. 39B includes a plot showing the on-target efficiency, using iGuide Seq assay, for the indicated integration sites. FIG. 39C includes schematics from the iGuide-Seq analysis showing that GS94 had no reproducible putatitve off-targets across two donors FIG. 39C discloses SEQ ID NOS 312-322, 312-313, and 323-331, respectively, in order of appearance.

FIG. 40 includes a schematic showing the iGuide-Seq workflow and data.

FIG. 41 includes a plot showing rhAmp-seg™ analysis of putative off-target sites identified by iGUIDE-seq and Elevation prediction.

FIG. 42 includes plots showing RNA-seq analysis of cells with GS94, GS102 and TRAC knock-in of CD19/MSLN circuits. Scatterplot of gene expression in cells with integration at the GS94 locus (y-axis) vs cells with integration at either the TRAC or the GS102 locus (x-axis) in two donors. The yellow dots correspond to ETS1 and FLI1. In blue are the genes that were found to be differentially expressed using edgeR (fold-change >0, FDR-corrected p-value <0.01, average counts-per-million across compared conditions at least 2).

FIG. 43 includes plots showing the absence of cytokine-independent growth in cells with CD19/MSLN circuit KI at GS94.

DETAILED DESCRIPTION

The present disclosure provides safe harbor loci and methods for identifying safe harbor loci that exhibit high integration efficiency (e.g., high knock-in (KI) efficiency), high and constant levels of transgene expression, and such benefits independent of T cell activation/differentiation state. In some embodiments, the safe harbor loci also exhibit minimal to no disruption to T cell function and/or capacity for product manufacturing. In some embodiments, these loci are useful for effective and safe integration and expression of transgenes in T cells (e.g. in CAR T therapies). In some embodiments, the methods described herein can be used for the identification of safe harbor loci for insertion of transgenes in other types of cells.
FIG. 1 illustrates the overall approach that the inventors of the present disclosure used to identify safe harbor loci. In some embodiments, the present disclosure provides a method comprising the identification of genes within a genome and non-coding regions with sustained expression in a treatment cell (e.g. T cell) and using a predictive model of KI efficiency as a function of T cell chromatic state and computational analysis to predict candidate integration sites. The method further comprises evaluating the candidate integration sites for actual KI efficiency, sustained levels of transgene expression of a transgene, and minimal disruption to the treatment cell phenotype (e.g., T cell function and/or capacity for treatment product expansion and manufacturing). In some embodiments, the safe harbor loci allow for integration of a transgene driven by an endogenous promoter. In some embodiments, the safe harbor loci allow for integration of a transgene driven by an exogenous promoter (e.g. EF1a promoter).
To facilitate an understanding of the present disclosure, a number of terms and phrases are defined below. Unless otherwise defined herein, scientific and technical terms used in this application shall have the meanings that are commonly understood by those of ordinary skill in the art. Generally, nomenclature used in connection with, and techniques of pharmacology, cell and tissue culture, molecular biology, cell and cancer biology, neurobiology, neurochemistry, virology, immunology, microbiology, genetics and protein and nucleic acid chemistry, described herein, are those well-known and commonly used in the art. In case of conflict, the present specification, including definitions, will control.
Unless otherwise defined, all terms of art, notations and other scientific terminology used herein are intended to have the meanings commonly understood by those of skill in the art. In some cases, terms with commonly understood meanings are defined herein for clarity and/or for ready reference, and the inclusion of such definitions herein should not necessarily be construed to represent a difference over what is generally understood in the art. The techniques and procedures described or referenced herein are generally well understood and commonly employed using conventional methodologies by those skilled in the art, such as, for example, the widely utilized molecular cloning methodologies described in Sambrook et al., Molecular Cloning: A Laboratory Manual 4th ed. (2012) Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. As appropriate, procedures involving the use of commercially available kits and reagents are generally carried out in accordance with manufacturer-defined protocols and conditions unless otherwise noted.
As used herein, the singular forms “a,” “an,” and “the” include the plural referents unless the context clearly indicates otherwise. The terms “include,” “such as,” and the like are intended to convey inclusion without limitation, unless otherwise specifically indicated.
As used herein, the term “comprising” also specifically includes embodiments “consisting of” and “consisting essentially of” the recited elements, unless specifically indicated otherwise.
The term “about” indicates and encompasses an indicated value and a range above and below that value. In certain embodiments, the term “about” indicates the designated value ±10%, ±5%, or ±1%. In certain embodiments, where applicable, the term “about” indicates the designated value(s) ±one standard deviation of that value(s).
As used herein, the term “gene” refers to the basic unit of heredity, consisting of a segment of DNA arranged along a chromosome, which codes for a specific protein or segment of protein. A gene typically includes a promoter, a 5′ untranslated region, one or more coding sequences (exons), optionally introns, a 3′ untranslated region. The gene may further comprise a terminator, enhancers and/or silencers.
As used herein, the term “locus” refers to a specific, fixed physical location on a chromosome where a gene or genetic marker is located.
As used herein, the term “target locus” refers to a locus on a chromosome within which a safe harbor locus can be used for the insertion of a sequence. A target locus can consist of multiple potential safe harbor loci (integration sites). Examples of target loci are provided in Table 4, as sgRNA target loci. The notation used for the sgRNA target loci in Table 4 refers to the genomic region of the target locus, defined by the chromosome of the target locus and the coordinate range for that target locus. For example, chr10:33130000-33140000 refers to a target locus on Chr10 (chromosome 10) starting from coordinate 33130000 and ending with coordinate 33140000.
The term “safe harbor locus” refers to a locus at which genes or genetic elements can be incorporated without disruption to expression or regulation of adjacent genes. These safe harbor loci are also referred to as safe harbor sites (SHS). As used herein, a safe harbor locus refers to an “integration site” or “knock-in site” at which a sequence encoding a transgene, as defined herein, can be inserted. In some embodiments the insertion occurs with replacement of a sequence that is located at the integration site. In some embodiments, the insertion occurs without replacement of a sequence at the integration site. Examples of integration sites contemplated are provided in Table 4.
As used herein, the term “insert” refers to a nucleotide sequence that is integrated (inserted) at a safe harbor site. The insert can be used to refer to the genes or genetic elements that are incorporated at the safe harbor site using, for example, homology-directed repair (HDR) CRISPR/Cas9 genome-editing or other methods for inserting nucleotide sequences into a genomic region known to those of ordinary skill in the art.
The “CRISPR/Cas” system refers to a widespread class of bacterial systems for defense against foreign nucleic acid. CRISPR/Cas systems are found in a wide range of eubacterial and archaeal organisms. CRISPR/Cas systems include type I, II, and III sub-types. Wild-type type II CRISPR/Cas systems utilize an RNA-mediated nuclease, Cas9 in complex with guide and activating RNA to recognize and cleave foreign nucleic acid. Guide RNAs having the activity of both a guide RNA and an activating RNA are also known in the art. In some cases, such dual activity guide RNAs are referred to as a small guide RNA (sgRNA).
Cas9 homologs are found in a wide variety of eubacteria, including, but not limited to bacteria of the following taxonomic groups: Actinobacteria, Aquificae, Bacteroidetes-Chlorobi, Chlamydiae-Verrucomicrobia, Chlroflexi, Cyanobacteria, Firmicutes, Proteobacteria, Spirochaetes, and Thermotogae. An exemplary Cas9 protein is the Streptococcus pyogenes Cas9 protein. Additional Cas9 proteins and homologs thereof are described in, e.g., Chylinksi, et al., RNA Biol. 2013 May 1; 10(5): 726-737; Nat. Rev. Microbiol. 2011 June; 9(6): 467-477; Hou, et al., Proc Natl Acad Sci USA. 2013 Sep. 24; 110(39):15644-9; Sampson et al., Nature. 2013 May 9; 497(7448):254-7; and Jinek, et al., Science. 2012 Aug. 17; 337(6096):816-21. The Cas9 nuclease domain can be optimized for efficient activity or enhanced stability in the host cell.
As used herein, the term “Cas9” refers to an RNA-mediated nuclease (e.g., of bacterial or archeal orgin, or derived therefrom). Exemplary RNA-mediated nuclases include the foregoing Cas9 proteins and homologs thereof, and include but are not limited to, CPF1 (See, e.g., Zetsche et al., Cell, Volume 163, Issue 3, p 759-771, 22 Oct. 2015). Similarly, as used herein, the term “Cas9 ribonucleoprotein” complex and the like refers to a complex between the Cas9 protein, and a crRNA (e.g., guide RNA or small guide RNA), the Cas9 protein and a trans-activating crRNA (tracrRNA), the Cas9 protein and a small guide RNA, or a combination thereof (e.g., a complex containing the Cas9 protein, a tracrRNA, and a crRNA guide RNA).
As used herein, the terms “T lymphocyte” and “T cell” are used interchangeably and refer to cells that have completed maturation in the thymus, and identify certain foreign antigens in the body. The terms also refer to the major leukocyte types that have various roles in the immune system, including activation and deactivation of other immune cells. The T cell can be any T cell such as a cultured T cell, e.g., a primary T cell, or a T cell derived from a cultured T cell line, e.g., a Jurkat, SupT1, etc., or a T cell obtained from a mammal. The T cell can be a CD3+ cell. The T cell can be any type of T cell, CD4+/CD8+ double positive T cells, CD4+ helper T cells (e.g. Th1 and Th2 cells), CD8+ T cells (e.g. cytotoxic T cells), peripheral Including but not limited to blood mononuclear cells (PBMC), peripheral blood leukocytes (PBL), tumor infiltrating lymphocytes (TIL), memory T cells, naive T cells, regulatory T cells, γδ T cells, etc. It can be any T cell at any stage of development. Additional types of helper T cells include Th3 (Treg) cells, Th17 cells, Th9 cells, or Tfh cells. Additional types of memory T cells include cells such as central memory T cells (Tcm cells), effector memory T cells (Tem cells and TEMRA cells). A T cell can also refer to a genetically modified T cell, such as a T cell that has been modified to express a T cell receptor (TCR) or a chimeric antigen receptor (CAR). T cells can also be differentiated from stem cells or progenitor cells.
“CD4+ T cells” refers to a subset of T cells that express CD4 on their surface and are associated with a cellular immune response. CD4+ T cells are characterized by a post-stimulation secretion profile that can include secretion of cytokines such as IFN-γ, TNF-α, IL-2, IL-4 and IL-10. “CD4” is a 55 kD glycoprotein originally defined as a differentiation antigen on T lymphocytes, but was also found on other cells including monocytes/macrophages. The CD4 antigen is a member of the immunoglobulin superfamily and has been implicated as an associative recognition element in MHC (major histocompatibility complex) class II restricted immune responses. On T lymphocytes, the CD4 antigen defines a helper/inducer subset.
“CD8+ T cells” refers to a subset of T cells that express CD8 on their surface, are MHC class I restricted, and function as cytotoxic T cells. The “CD8” molecule is a differentiation antigen present on thymocytes, as well as on cytotoxic and suppressor T lymphocytes. The CD8 antigen is a member of the immunoglobulin superfamily and is an associative recognition element in major histocompatibility complex class I restriction interactions.
As used herein, the term “ex vivo” generally includes experiments or measurements made in or on living tissue, preferably in an artificial environment outside the organism, preferably with minimal differences from natural conditions.
As used herein, the term “construct” refers to a complex of molecules, including macromolecules or polynucleotides.
As used herein, the term “integration” refers to the process of stably inserting one or more nucleotides of a construct into the cell genome, i.e., covalently linking to a nucleic acid sequence in the chromosomal DNA of the cell. It may also refer to nucleotide deletions at a site of integration. Where there is a deletion at the insertion site, “integration” may further include substitution of the endogenous sequence or nucleotide deleted with one or more inserted nucleotides.
As used herein, the term “exogenous” refers to a molecule or activity that has been introduced into a host cell and is not native to that cell. The molecule can be introduced, for example, by introduction of the encoding nucleic acid into host genetic material, such as by integration into a host chromosome, or as non-chromosomal genetic material, such as a plasmid. Thus, the term, when used in connection with expression of an encoding nucleic acid, refers to the introduction of the encoding nucleic acid into a cell in an expressible form. The term “endogenous” refers to a molecule or activity that is present in a host cell under natural, unedited conditions. Similarly, the term, when used in connection with expression of the encoding nucleic acid, refers to expression of the encoding nucleic acid that is contained within the cell and not introduced exogenously.
As used herein, a “polynucleotide donor construct” refers to a nucleotide sequence (e.g. DNA sequence) that is genetically inserted into a polynucleotide and is exogenous to that polynucleotide. The polynucleotide donor construct is transcribed into RNA and optionally translated into a polypeptide. The polynucleotide donor construct can include prokaryotic sequences, cDNA from eukaryotic mRNA, genomic DNA sequences from eukaryotic (e.g., mammalian) DNA, and synthetic DNA sequences. For example, the polynucleotide donor construct can be a miRNA, shRNA, natural polypeptide (i.e., a naturally occurring polypeptide) or fragment thereof or a variant polypeptide (e.g. a natural polypeptide having less than 100% sequence identity with the natural polypeptide) or fragments thereof.
As used herein, the term “transgene” refers to a polynucleotide that has been transferred naturally, or by any of a number of genetic engineering techniques from one organism to another. It is optionally translated into a polypeptide. It is optionally translated into a recombinant protein. A “recombinant protein” is a protein encoded by a gene—recombinant DNA—that has been cloned in a system that supports expression of the gene and translation of messenger RNA (see expression system). The recombinant protein can be a therapeutic agent, e.g. a protein that treats a disease or disorder disclosed herein. As used, transgene can refer to a polynucleotide that encodes a polypeptide. A transgene can also refer to a non-encoding sequence, such as, but not limited to shRNAs, miRNAs, and miRs.
The terms “protein,” “polypeptide,” and “peptide” are used herein interchangeably.
As used herein, the term “operably linked” refers to the binding of a nucleic acid sequence to a single nucleic acid fragment such that one function is affected by the other. For example, if a promoter is capable of affecting the expression of a coding sequence or functional RNA (i.e., the coding sequence or functional RNA is under transcriptional control by the promoter), the promoter is operably linked thereto. Coding sequences can be operably linked to control sequences in both sense and antisense orientation.
As used herein, the term “developmental cell states” refers to, for example, states when the cell is inactive, actively expressing, differentiating, senescent, etc. developmental cell state may also refer to a cell in a precursor state (e.g., a T cell precursor).
As used, the term “encoding” refers to a sequence of nucleic acids which codes for a protein or polypeptide of interest. The nucleic acid sequence may be either a molecule of DNA or RNA. In preferred embodiments, the molecule is a DNA molecule. In other preferred embodiments, the molecule is a RNA molecule. When present as a RNA molecule, it will comprise sequences which direct the ribosomes of the host cell to start translation (e.g., a start codon, ATG) and direct the ribosomes to end translation (e.g., a stop codon). Between the start codon and stop codon is an open reading frame (ORF). Such terms are known to one of ordinary skill in the art.
The term “inserting” refers to a manipulation of a nucleotide sequence to introduce a non-native sequence. This is done, for example, via the use of restriction enzymes and ligases whereby the DNA sequence of interest, usually encoding the gene of interest, can be incorporated into another nucleic acid molecule by digesting both molecules with appropriate restriction enzymes in order to create compatible overlaps and then using a ligase to join the molecules together. One skilled in the art is very familiar with such manipulations and examples may be found in Sambrook et al. (Sambrook, Fritsch, & Maniatis, “Molecular Cloning: A Laboratory Manual”, 2nd ed., Cold Spring Harbor Laboratory, 1989), which is hereby incorporated by reference in its entirety including any drawings, figures and tables.
As used herein, the term “subject” refers to a mammalian subject. Exemplary subjects include humans, monkeys, dogs, cats, mice, rats, cows, horses, camels, goats, rabbits, pigs and sheep. In certain embodiments, the subject is a human. In some embodiments the subject has a disease or condition that can be treated with an engineered cell provided herein or population thereof. In some aspects, the disease or condition is a cancer.
As used herein, the term “promoter” refers to a nucleotide sequence (e.g. DNA sequence) capable of controlling the expression of a coding sequence or functional RNA. The promoter sequence consists of proximal and more distal upstream elements, the latter elements often referred to as enhancers. A promoter can be derived from natural genes in its entirety, can be composed of different elements from different promoters found in nature, and/or may comprise synthetic DNA segments. A promoter, as contemplated herein, can be endogenous to the cell of interest or exogenous to the cell of interest. It is appreciated by those skilled in the art that different promoters can induce gene expression in different tissue or cell types, or at different developmental stages, or in response to different environmental conditions. As is known in the art, a promoter can be selected according to the strength of the promoter and/or the conditions under which the promoter is active, e.g., constitutive promoter, strong promoter, weak promoter, inducible/repressible promoter, tissue specific Or developmentally regulated promoters, cell cycle-dependent promoters, and the like.
A promoter can be an inducible promoter (e.g., a heat shock promoter, tetracycline-regulated promoter, steroid-regulated promoter, metal-regulated promoter, estrogen receptor-regulated promoter, etc.). The promoter can be a constitutive promoter (e.g., CMV promoter, UBC promoter). In some embodiments, the promoter can be a spatially restricted and/or temporally restricted promoter (e.g., a tissue specific promoter, a cell type specific promoter, etc.). See for example U.S. application Ser. No. 15/715,068, the disclosures of which are herein incorporated by reference in their entirety.
Gene editing, as contemplated herein, may involve a gene (or nucleotide sequence) knock-in or knock-out. As used herein, the term “knock-in” refers to an addition of a DNA sequence, or fragment thereof into a genome. Such DNA sequences to be knocked-in may include an entire gene or genes, may include regulatory sequences associated with a gene or any portion or fragment of the foregoing. For example, a polynucleotide donor construct encoding a recombinant protein may be inserted into the genome of a cell carrying a mutant gene. In some embodiments, a knock-in strategy involves substitution of an existing sequence with the provided sequence, e.g., substitution of a mutant allele with a wild-type copy. On the other hand, the term “knock-out” refers to the elimination of a gene or the expression of a gene. For example, a gene can be knocked out by either a deletion or an addition of a nucleotide sequence that leads to a disruption of the reading frame. As another example, a gene may be knocked out by replacing a part of the gene with an irrelevant (e.g., non-coding) sequence.
As used herein, the term “non-homologous end joining” or NHEJ refers to a cellular process in which cut or nicked ends of a DNA strand are directly ligated without the need for a homologous template nucleic acid. NHEJ can lead to the addition, the deletion, substitution, or a combination thereof, of one or more nucleotides at the repair site.
As used herein, the term “homology directed repair” or HDR refers to a cellular process in which cut or nicked ends of a DNA strand are repaired by polymerization from a homologous template nucleic acid. Thus, the original sequence is replaced with the sequence of the template. The homologous template nucleic acid can be provided by homologous sequences elsewhere in the genome (sister chromatids, homologous chromosomes, or repeated regions on the same or different chromosomes). Alternatively, an exogenous template nucleic acid can be introduced to obtain a specific HDR-induced change of the sequence at the target site. In this way, specific mutations can be introduced at the cut site.
The terms “vector” and “plasmid” are used interchangeably and as used herein refer to polynucleotide vehicles useful to introduce genetic material into a cell. Vectors can be linear or circular. Vectors can integrate into a target genome of a host cell or replicate independently in a host cell. Vectors can comprise, for example, an origin of replication, a multicloning site, and/or a selectable marker. An expression vector typically comprises an expression cassette. Vectors and plasmids include, but are not limited to, integrating vectors, prokaryotic plasmids, eukaryotic plasmids, plant synthetic chromosomes, episomes, viral vectors, cosmids, and artificial chromosomes.
As used herein the term “expression cassette” is a polynucleotide construct, generated recombinantly or synthetically, comprising regulatory sequences operably linked to a selected polynucleotide to facilitate expression of the selected polynucleotide in a host cell. For example, the regulatory sequences can facilitate transcription of the selected polynucleotide in a host cell, or transcription and translation of the selected polynucleotide in a host cell. An expression cassette can, for example, be integrated in the genome of a host cell or be present in an expression vector.
As used herein, the phrase “subject in need thereof” refers to a subject that exhibits and/or is diagnosed with one or more symptoms or signs of a disease or disorder as described herein.
A “chemotherapeutic agent” refers to a chemical compound useful in the treatment of cancer. Chemotherapeutic agents include “anti-hormonal agents” or “endocrine therapeutics” which act to regulate, reduce, block, or inhibit the effects of hormones that can promote the growth of cancer.
The term “composition” refers to a mixture that contains, e.g., an engineered cell or protein contemplated herein. In some embodiments, the composition may contain additional components, such as adjuvants, stabilizers, excipients, and the like. The term “composition” or “pharmaceutical composition” refers to a preparation which is in such form as to permit the biological activity of an active ingredient contained therein to be effective in treating a subject, and which contains no additional components which are unacceptably toxic to the subject in the amounts provided in the pharmaceutical composition.
As used herein, the term “effective amount” refers to the amount of a compound (e.g., a compositions described herein, cells described herein) sufficient to effect beneficial or desired results. An effective amount can be administered in one or more administrations, applications or dosages and is not intended to be limited to a particular formulation or administration route. As used herein, the term “treating” includes any effect, e.g., lessening, reducing, modulating, ameliorating or eliminating, that results in the improvement of the condition, disease, disorder, and the like, or ameliorating a symptom thereof.
The terms “modulate” and “modulation” refer to reducing or inhibiting or, alternatively, activating or increasing, a recited variable.
The terms “increase” and “activate” refer to an increase of 10%, 20%, 30%, 40%, 50%, 60%, 70%, 75%, 80%, 85%, 90%, 95%, 100%, 2-fold, 3-fold, 4-fold, 5-fold, 10-fold, 50-fold, 100-fold, or greater in a recited variable.
The terms “reduce” and “inhibit” refer to a decrease of 10%, 20%, 30%, 40%, 50%, 60%, 70%, 75%, 80%, 85%, 90%, 95%, 2-fold, 3-fold, 4-fold, 5-fold, 10-fold, 20-fold, 100-fold, or greater in a recited variable.
1. Safe Harbor Loci
Gene editing therapies include, for example, viral vector integration and site specific integration. Site-specific integration is a promising alternative to random integration of viral vectors, as it mitigates the risks of insertional mutagenesis or insertional oncogenesis (Kolb et al. Trends Biotechnol. 2005 23:399-406; Porteus et al. Nat Biotechnol. 2005 23:967-973; Paques et al. Curr Gen Ther. 2007 7:49-66). However, site specific integration continues to face challenges such as poor knock-in efficiency, risk of insertional oncogenesis, unstable and/or anomalous expression of adjacent genes or the transgene, low accessibility (e.g. within kB of adjacent genes), etc. These challenges can be addressed, in part, through the identification and use of safe harbor loci or safe harbor sites (SHS), which are sites in which genes or genetic elements can be incorporated without disruption to expression or regulation of adjacent genes.
The most widely used of the putative human safe harbor sites is the AAVS1 site on chromosome 19q, which was initially identified as a site for recurrent adenoassociated virus insertion. Other potential SHS have been identified on the basis of homology, with sites first identified in other species (e.g., the human homolog of the permissive murine Rosa26 locus) or among the growing number of human genes that appear non-essential under some circumstances. One putative SHS of this type is the CCR5 chemokine receptor gene, which, when disrupted, confers resistance to human immunodeficiency virus infection. Additional potential genomic SHS have been identified in human and other cell types on the basis of viral integration site mapping or gene-trap analyses, as was the original murine Rosa26 locus. The three top SHS, AAVS1, CCR5, and Rosa26, are in close proximity to many protein coding genes and regulatory elements. (See FIG. 2 from Sadelain, M., et al. (2012). Safe harbours for the integration of new DNA in the human genome. Nature reviews Cancer, 12(1), 51-58, the relevant disclosures of which are herein incorporated by reference in their entirety).
The AAVS1 (also known as the PPP 1R12C locus) on human chromosome 19 is a known SHS for hosting transgenes (e.g. DNA transgenes) with expected function. It is at position 19q13.42. It has an open chromatin structure and is transcription-competent. The canonical SHS locus for AAVS1 is chr19: 55,625,241-55,629,351. See Pellenz et al. “New Human Chromosomal Sites with “Safe Harbor” Potential for Targeted Transgene Insertion.” Human gene therapy vol. 30,7 (2019): 814-828, the relevant disclosures of which are herein incorporated by reference. An exemplary AAVS1 target gRNA and target sequence are provided below:

	AAVS1-gRNA sequence:
	(SEQ ID NO: 121)
	ggggccactagggacaggatGTTTTAGAGCTAGAA

	ATAGCAAGTTAAAATAAGGCTAGTCCGTTATCAAC

	TTGAAAAAGTGGCACCGAGTCGGTGCTTTTTTT

	AAVS1 target sequence:
	(SEQ ID NO: 122)
	ggggccactagggacaggat

CCR5, which is located on chromosome 3 at position 3p21.31, encodes the major co-receptor for HIV-1. Disruption at this site in the CCR5 gene has been beneficial in HIV/AIDS therapy and prompted the development of zinc-finger nucleases that target its third exon. The canonical SHS locus for CCR5 is chr3: 46,414,443-46,414,942. See Pellenz et al. “New Human Chromosomal Sites with “Safe Harbor” Potential for Targeted Transgene Insertion.” Human gene therapy vol. 30,7 (2019): 814-828, the relevant disclosures of which are herein incorporated by reference.
The mouse Rosa26 locus is particularly useful for genetic modification as it can be targeted with high efficiency and is expressed in most cell types tested. Irion et al. 2007 (“Identification and targeting of the ROSA26 locus in human embryonic stem cells.” Nature biotechnology 25.12 (2007): 1477-1482, the relevant disclosure of which are herein incorporated by reference) identified the human homolog, human ROSA26, in chromosome 3 (position 3p25.3). The canonical SHS locus for human Rosa26 (hRosa26) is chr3: 9,415,082-9,414,043. See Pellenz et al. “New Human Chromosomal Sites with “Safe Harbor” Potential for Targeted Transgene Insertion.” Human gene therapy vol. 30,7 (2019): 814-828, the relevant disclosures of which are herein incorporated by reference.
Additional examples of safe harbor sites are provided in Pellenz et al. “New Human Chromosomal Sites with “Safe Harbor” Potential for Targeted Transgene Insertion.” Human gene therapy vol. 30,7 (2019): 814-828, the relevant disclosures of which are herein incorporated by reference.
The present disclosure is directed to methods for identifying safe harbor loci with benefits including, but not limited to, high knock-in efficiency and high expression of transgene. An example of applications of the presently disclosed methods is the identification of safe harbor loci for insertion of transgenes (e.g., chimeric antigen receptors (CAR)) into T-cells. In some embodiments, the safe harbor loci of the present disclosure are useful for the insertion of a sequence encoding a transgene. In some embodiments, the safe harbor sites allow for high transgene expression (sufficient to allow for transgene functionality or treatment of a disease of interest) and stable expression of the transgene over several days, weeks or months. In some embodiments, knockout of the gene at the safe harbor locus confers benefit to the function of the cell, or the gene at the safe harbor locus has no known function within the cell. In some embodiments the safe harbor locus results in stable transgene expression in vitro with or without CD3/CD28 stimulation, negligible off-target cleavage as detected by iGuide-Seq or CRISPR-Seq, less off-target cleavage relative to other loci as detected by iGuide-Seq or CRISPR-Seq, negligible transgene-independent cytotoxicity, negligible transgene-independent cytokine expression, negligible transgene-independent chimeric antigen receptor expression, negligible deregulation or silencing of nearby genes, and positioned outside of a cancer-related gene.
As used, a “nearby gene” can refer to a gene that is within about 100 kB, about 125 kB, about 150 kB, about 175 kB, about 200 kB, about 225 kB, about 250 kB, about 275 kB, about 300 kB, about 325 kB, about 350 kB, about 375 kB, about 400 kB, about 425 kB, about 450 kB, about 475 kB, about 500 kB, about 525 kB, about 550 kB away from the safe harbor locus (integration site).
In some embodiments, the present disclosure contemplates inserts that comprise one or more transgenes. The transgene can encode a therapeutic protein, an antibody, a peptide, a suicide gene, an apoptosis gene or any other gene of interest. The safe harbor loci identified using the method described herein allow for transgene integration that results in, for example, enhanced therapeutic properties. These enhanced therapeutic properties, as used herein, refer to an enhanced therapeutic property of a cell when compared to a typical immune cell of the same normal cell type. For example, an NK cell having “enhanced therapeutic properties” has an enhanced, improved, and/or increased treatment outcome when compared to a typical, unmodified and/or naturally occurring NK cell. The therapeutic properties of immune cells can include, but are not limited to, cell transplantation, transport, homing, viability, self-renewal, persistence, immune response control and regulation, survival, and cytotoxicity. The therapeutic properties of immune cells are also manifested by: antigen-targeted receptor expression; HLA presentation or lack thereof; tolerance to the intratumoral microenvironment; induction of bystander immune cells and immune regulation; improved target specificity with reduction; resistance to treatments such as chemotherapy.
As used herein, the term “insert size” refers to the length of the nucleotide sequence being integrated (inserted) at the safe harbor site. In some embodiments, the insert size comprises at least about 100, 200, 300, 400 or 500 basepairs. In some embodiments, the insert size comprises about 500 nucleotides or basepairs. In some embodiments, the insert size comprises up to 0.5, 0.6, 0.7, 0.8, 0.9, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 kbp (kilo basepairs) or the sizes in between. In some embodiments, the insert size is greater than 0.5, 0.6, 0.7, 0.8, 0.9, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 kbp or the sizes in between. In some embodiments, the insert size is within the range of 3-15 kbp or is any number in that range. In some embodiments, the insert size is within the range of 1.5-8.3 kbp or is any number in that range. In some embodiments, the insert size is within the range of 1.5-15 kbp or is any number in that range. In some embodiments, the insert size is within the range of 0.5-20 kbp or is any number in that range. In some embodiments, the insert size is 0.5-10, 0.6-10, 0.7-10, 0.8-10, 0.9-10, 1-10, 2-10, 3-10, 4-10, 5-10, 6-10, 7-10, 8-10, 9-10 kbp. In some embodiments, the insert size is 0.5-11, 0.6-11, 0.7-11, 0.8-11, 0.9-11, 1-11, 2-11, 3-11, 4-11, 5-11, 6-11, 7-11, 8-11, 9-11, or 10-11 kbp. In some embodiments, the insert size is 0.5-12, 0.6-12, 0.7-12, 0.8-12, 0.9-12, 1-12, 2-12, 3-12, 4-12, 5-12, 6-12, 7-12, 8-12, 9-12, 10-12, or 11-12 kbp. In some embodiments, the insert size is 0.5-13, 0.6-13, 0.7-13, 0.8-13, 0.9-13, 1-13, 2-13, 3-13, 4-13, 5-13, 6-13, 7-13, 8-13, 9-13, 10-13, 11-13, or 12-13 kbp. In some embodiments, the insert size is 0.5-14, 0.6-14, 0.7-14, 0.8-14, 0.9-14, 1-14, 2-14, 3-14, 4-14, 5-14, 6-14, 7-14, 8-14, 9-14, 10-14, 11-14, 12-14 or 13-14 kbp. In some embodiments, the insert size is 0.5-15, 0.6-15, 0.7-15, 0.8-15, 0.9-15, 2-15, 3-15, 4-15, 5-15, 6-15, 7-15, 8-15, 9-15, 10-15, 11-15, 12-15, 13-15, or 14-15 kbp. In some embodiments, the insert size is 0.5-16, 0.6-16, 0.7-16, 0.8-16, 0.9-16, 1-16, 2-16, 3-16, 4-16, 5-16, 6-16, 7-16, 8-16, 9-16, 10-16, 11-16, 12-16, 13-16, 14-16 or 15-16 kbp. In some embodiments, the insert size is 0.5-17, 0.6-17, 0.7-17, 0.8-17, 0.9-17, 1-17, 2-17, 3-17, 4-17, 5-17, 6-17, 7-17, 8-17, 9-17, 10-17, 11-17, 12-17, 13-17, or 14-17, 15-17 or 16-17 kbp. In some embodiments, the insert size is 0.5-18, 0.6-18, 0.7-18, 0.8-18, 0.9-18, 1-18, 2-18, 3-18, 4-18, 5-18, 6-18, 7-18, 8-18, 9-18, 10-18, 11-18, 12-18, 13-18, 14-18, 15-18, 16-18 or 17-18 kbp. In some embodiments, the insert size is 0.5-19, 0.6-19, 0.7-19, 0.8-19, 0.9-19, 1-19, 2-19, 3-19, 4-19, 5-19, 6-19, 7-19, 8-19, 9-19, 10-19, 11-19, 12-19, 13-19, 14-0.7-20, 19, 15-19, 16-19, 17-19, or 18-19 kbp. In some embodiments, the insert size is 0.5-20, 0.6-20, 0.7-20, 0.8-20, 0.9-20, 1-20, 2-20, 3-20, 4-20, 5-20, 6-20, 7-20, 8-20, 9-20, 10-20, 11-20, 12-20, 13-20, 14-20, 15-20, 16-20, 17-20, 18-20, or 19-20 kbp.
The inserts of the present disclosure refer to nucleic acid molecules or polynucleotide inserted at a safe harbor site. In some embodiments, the nucleotide sequence is a DNA molecule, e.g., genomic DNA, or comprises deoxy-ribonucleotides. In some embodiments, the insert comprises a smaller fragment of DNA, such as a plastid DNA, mitochondrial DNA, or DNA isolated in the form of a plasmid, a fosmid, a cosmid, a bacterial artificial chromosome (BAC), a yeast artificial chromosome (YAC), and/or any other sub-genome segment of DNA. In some embodiments, the insert is an RNA molecule or comprises ribonucleotides. The nucleotides in the insert are contemplated as naturally occurring nucleotides, non-naturally occurring, and modified nucleotides. Nucleotides may be modified chemically or biochemically, or may contain non-natural or derivatized nucleotide bases, as will be readily appreciated by those of skill in the art. Such modifications include, for example, labels, methylation, substitution of one or more of the naturally occurring nucleotides with an analog, internucleotide modifications. The polynucleotides can be in any topological conformation, including single-stranded, double-stranded, partially duplexed, triplexed, hairpinned, circular conformations, and other three-dimension conformations contemplated in the art.
The inserts can have coding and/or non-coding regions. The insert can comprises a non-coding sequence (e.g., control elements, e.g., a promoter sequence). In some embodiments, the insert encodes transcription factors. In some embodiments, the insert encodes an antigen binding receptors such as single receptors, T-cell receptors (TCRs), syn-notch, CARs, mAbs, etc. In some embodiments, the inserts are RNAi molecules, including, but not limited to, miRNAs, siRNA, shRNAs, etc. In some embodiments, the insert is a human sequence. In some embodiments, the insert is chimeric. In some embodiments, the insert is a multi-gene/multi-module therapeutic cassette. A multi-gene/multi-module therapeutic cassette referst to an insert or cassette having one or more than one receptor (e.g., synthetic receptors), other exogenous protein coding sequences, non-coding RNAs, transcriptional regulatory elements, and/or insulator sequences, etc.
Various cell types are contemplated as having the safe harbor sites in the present disclosure. A cell comprising a safe harbor site and/or a cell comprising an insert at a safe harbor site as described in the present disclosure can be referred to as an engineered cell. The cells can include, but are not limited to, eukaryotic cells, prokaryotic cells, animal cells, plant cells, fungal cells and the like. Optionally, the cell is a mammalian cell, for example, a human cell. In some embodiments, that engineered cell is a stem cell, a human cell, a primary cell, an hematopoietic cell, an adaptive immune cell, an innate immune cell, a T cell or a T cell progenitor. Non-limiting examples of immune cells that are contemplated in the present disclosure include T cell, B cell, natural killer (NK) cell, NKT/iNKT cell, macrophage, myeloid cell, and dendritic cells. Non-limiting examples of stem cells that are contemplated in the present disclosure include pluripotent stem cells (PSCs), embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), embryo-derived embryonic stem cells obtained by nuclear transfer (ntES; nuclear transfer ES), male germline stem cells (GS cells), embryonic germ cells (EG cells), hematopoietic stem/progenitor stem cells (HSPCs), somatic stem cells (adult stem cells), hemangioblasts, neural stem cells, mesenchymal stem cells and stem cells of other cells (including osteocyte, chondrocyte, myocyte, cardiac myocyte, neuron, tendon cell, adipocyte, pancreocyte, hepatocyte, nephrocyte and follicle cells and so on). In some embodiments, the engineered cells is a T cell, NK cells, iPSC, and HSPC. In some embodiments, the engineered cells used in the present disclosure are human cell lines grown in vitro (e.g. deliberately immortalized cell lines, cancer cell lines, etc.).
The methods for integrating the inserts at the safe harbor sites can be viral or non-viral delivery techniques.
In some embodiments, the nucleic acid sequence is inserted into the genome of the engineered cell by introducing a vector, for example, a viral vector, comprising the nucleic acid. Examples of viral vectors include, but are not limited to, adeno-associated viral (AAV) vectors, retroviral vectors or lentiviral vectors. In some embodiments, the lentiviral vector is an integrase-deficient lentiviral vector.
In some embodiments, the nucleic acid sequence is inserted into the genome of the T cell via non-viral delivery. In non-viral delivery methods, the nucleic acid can be naked DNA, or in a non-viral plasmid or vector. Non-viral delivery techniques can be site-specific integration techniques, as described herein or known to those of ordinary skill in the art. Examples of site-specific techniques for integration into the safe harbor loci include, without limitation, homology-dependent engineering using nucleases and homology independent targeted insertion using Cas9.
In some embodiments, the insert is integrated at a safe harbor site by introducing into the engineered cell, (a) a targeted nuclease that cleaves a target region in the safe harbor site to create the insertion site; and (b) the nucleic acid sequence (insert), wherein the insert is incorporated at the insertion site by, e.g., HDR. Examples of non-viral delivery techniques that can be used in the methods of the present disclosure are provided in U.S. application Ser. Nos. 16/568,116 and 16/622,843, the relevant disclosures of which are herein incorporated by reference in their entirety.
2. CAR T Cell Therapy
Chimeric antigen receptor (CAR) T cells are T cells that have been genetically engineered to produce an artificial T-cell receptor for use in immunotherapy. Chimeric antigen receptors are receptor proteins that have been engineered to confer T cells with the ability to target a specific protein. The genetic modification of lymphocytes (e.g. T cells) by incorporation of, for example, CARs, and administration of the engineered cells to a subject is an example of “adoptive cell therapy”. As used herein, the term “adoptive cell therapy” refers to cell-based immunotherapy for transfusion of autologous or allogeneic lymphocytes, referred to as T cells or B cells. In this CAR therapy approach, cells are expanded and cultured ex vivo and genetically modified, prior to transfusion.
The expression of CARs allows the engineered T-cells to target and bind specific proteins, for example, tumor antigens. In CAR therapy, T-cells are harvested from a subject—they can be autologous T-cells from the subject own blood or from a donor that will not be receiving the CAR therapy. Once isolated, the T-cells are genetically modified with a CAR, expanded ex vivo, and administered to the subject (i.e. patient) by, e.g. infusion.
The CARs may be introduced into the T-cells using, for example, a viral technique (e.g., retroviral integration) or site-specific technique. With site specific integration of the transgenes (e.g. CARs), the transgenes may be targeted to a safe harbor locus. Examples of site-specific techniques for integration into the safe harbor loci include, without limitation, homology-dependent engineering using nucleases and homology independent targeted insertion using Cas9.
The engineered CAR T cells have applications to immune-oncology. The CAR, for example, can be selected to target a specific tumor antigen. Examples of cancers that can be effectively targeted using CAR T cells are blood cancers. In some embodiments, CAR T cell therapy can be used to treat solid tumors.
3. Gene Editing
The terms “gene editing” or “genome editing”, as used herein, refer to a type of genetic manipulation in which DNA is inserted, replaced, or removed from the genome using artificially manipulated nucleases or “molecular scissors”. It is a useful tool for elucidating the function and effect of sequence-specific genes or proteins or altering cell behavior (e.g. for therapeutic purposes).
Currently available genome editing tools include zinc finger nucleases (ZFN) and transcription activator-like effector nucleases (TALENs) to incorporate genes at safe harbor loci (e.g. the adeno-associated virus integration site 1 (AAVS1) safe harbor locus). The DICE (dual integrase cassette exchange) system utilizing phiC31 integrase and Bxb1 integrase is a tool for target integration. Additionally, clustered regularly interspaced short palindromic repeat/Cas9 (CRISPR/Cas9) techniques can be used for targeted gene insertion.
Site specific gene editing approaches can include homology dependent mechanisms or homology independent mechanisms.
All methods known in the art for targeted insertion of gene sequences are contemplated in the methods described herein to insert constructs at safe harbor loci.
4. Crispr-Cas Gene Editing
One effective example of gene editing is the Crisp-Cas approach (e.g. Crispr-Cas9). This approach incorporates the use of a guide polynucleotide (e.g. guide ribonucleic acid or gRNA) and a cas endonuclease (e.g. Cas9 endonuclease).
As used herein, a polypeptide referred to as a “Cas endonuclease” or having “Cas endonuclease activity” refers to a CRISPR-related (Cas) polypeptide encoded by a Cas gene, wherein a Cas polypeptide is a target DNA sequence that can be cleaved when operably linked to one or more guide polynucleotides (see, e.g., U.S. Pat. No. 8,697,359). Also included in this definition are variants of Cas endonuclease that retain guide polynucleotide-dependent endonuclease activity. The Cas endonuclease used in the donor DNA insertion method detailed herein is an endonuclease that introduces double-strand breaks into DNA at the target site (e.g., within the target locus or at the safe harbor site).
As used herein, the term “guide polynucleotide” relates to a polynucleotide sequence capable of complexing with a Cas endonuclease and allowing the Cas endonuclease to recognize and cleave a DNA target site. The guide polynucleotide can be a single molecule or a double molecule. The guide polynucleotide sequence can be an RNA sequence, a DNA sequence, or a combination thereof (RNA-DNA combination sequence). A guide polynucleotide comprising only ribonucleic acid is also referred to as “guide RNA”. In some embodiments, a polynucleotide donor construct is inserted at a safe harbor locus using a guide RNA (gRNA) in combination with a cas endonuclease (e.g. Cas9 endonuclease).
The guide polynucleotide includes a first nucleotide sequence domain (also referred to as a variable targeting domain or VT domain) that is complementary to a nucleotide sequence in the target DNA, and a second nucleotide that interacts with a Cas endonuclease polypeptide. It can be a double molecule (also referred to as a double-stranded guide polynucleotide) comprising a sequence domain (referred to as a Cas endonuclease recognition domain or CER domain). The CER domain of this double molecule guide polynucleotide comprises two separate molecules that hybridize along the complementary region. The two separate molecules can be RNA sequences, DNA sequences and/or RNA-DNA combination sequences.
Genome editing using CRISPR-Cas approaches relies on the repair of site-specific DNA double-strand breaks (DSBs) induced by the RNA-guided Cas endonuclease (e.g. Cas 9 endonuclease). Homology-directed repair (HDR) of these DSBs enables precise editing of the genome by introducing defined genomic changes, including base substitutions, sequence insertions, and deletions. Conventional HDR-based CRISPR/Cas9 genome-editing involves transfecting cells with Cas9, gRNA and donor DNA containing homologous arms matching the genomic locus of interest.
HITI (homology independent targeted insertion) uses a non-homologous end joining (NHEJ)-based homology-independent strategy and the method can be more efficient than HDR. Guide RNAs (gRNAs) target the insertion site. For HITI, donor plasmids lack homology arms and DSB repair does not occur through the HDR pathway. The donor polynucleotide construct can be engineered to include Cas9 cleavage site(s) flanking the gene or sequence to be inserted. This results in Cas9 cleavage at both the donor plasmid and the genomic target sequence. Both target and donor have blunt ends and the linearized donor DNA plasmid is used by the NHEJ pathway resulting integration into the genomic DSB site. (See, for example, Suzuki, K., et al. (2016). In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration. Nature, 540(7631), 144-149, the relevant disclosures of which are herein incorporated in their entirety).
Methods for conducing gene editing using CRISPR-Cas approaches are known to those of ordinary skill in the art. (See, for example, U.S. application Ser. No. 16/312,676, U.S. Ser. No. 15/303,722, and U.S. Ser. No. 15/628,533, the disclosures of which are herein incorporated by reference in their entirety). Additionally, uses of endonucleases for inserting transgenes into safe harbor loci are described, for example, in U.S. application Ser. No. 13/036,343, the disclosures of which are herein incorporated by reference in their entirety.
The guide RNAs and/or mRNA (or DNA) encoding an endonuclease can be chemically linked to one or more moieties or conjugates that enhance the activity, cellular distribution, or cellular uptake of the oligonucleotide. Non-limiting examples of such moieties include lipid moieties such as a cholesterol moiety, cholic acid, a thioether, a thiocholesterol, an aliphatic chain (e.g., dodecandiol or undecyl residues), a phospholipid, e.g., di-hexadecyl-rac-glycerol or triethylammonium 1,2-di-O-hexadecyl-rac-glycero-3-H-phosphonate, a polyamine or a polyethylene glycol chain, adamantane acetic acid, a palmityl moiety and an octadecylamine or hexylamino-carbonyl-t oxycholesterol moiety. See for example U.S. application Ser. No. 15/715,068, the disclosures of which are herein incorporated by reference in their entirety.
5. Therapeutic Applications
For therapeutic applications, the engineered cells, populations thereof, or compositions thereof are administered to a subject, generally a mammal, generally a human, in an effective amount.
The engineered cells may be administered to a subject by infusion (e.g., continuous infusion over a period of time) or other modes of administration known to those of ordinary skill in the art.
The engineered cells provided herein can be administered as part of a pharmaceutical compositions. In some embodiments, the present disclosure provides compositions comprising a guide RNA of the present disclosure. The pharmaceutical composition may comprise one or more pharmaceutical excipients. Any suitable pharmaceutical excipient may be used, and one of ordinary skill in the art is capable of selecting suitable pharmaceutical excipients. Accordingly, the pharmaceutical excipients provided below are intended to be illustrative, and not limiting. Additional pharmaceutical excipients include, for example, those described in the Handbook of Pharmaceutical Excipients, Rowe et al. (Eds.) 6th Ed. (2009), incorporated by reference in its entirety.
The engineered cells provided herein not only find use in gene therapy but also in non-pharmaceutical uses such as, e.g., production of animal models and production of recombinant cell lines expressing a protein of interest.
The engineered cells of the present disclosure can be any cell, generally a mammalian cell, generally a human cell that has been modified by integrating a transgene at a safe harbor locus described herein. In some embodiments, the engineered cells are immune cells. In some embodiments, the engineered cells are lymphocytes. In some embodiments, the engineered cells are T cells or T cell precursors.
The engineered cells, compositions and methods of the present disclosure are useful for therapeutic applications such as CAR T cell therapy and TCR T cell therapy. In some embodiments, the insertion of a sequence encoding a transgene within a safe harbor locus maintains the TCR expression relative to instances when there is no insertion and enables transgene expression while maintaining TCR function.
Various diseases treated using the engineered cells, populations thereof, or compositions thereof are provided herein. Non-limiting examples of such diseases include alopecia areata, autoimmune hemolytic anemia, autoimmune hepatitis, cancer, dermatomyositis, diabetes (type 1), certain juvenile idiopathic arthritis, glomerulonephritis, Graves' disease, Guillain Valley Syndrome, idiopathic thrombocytopenic purpura, myasthenia gravis, certain myocarditis, multiple sclerosis, pemphigus/pemphigoid, pernicious anemia, polyarteritis nodosa, polymyositis, primary bile With cirrhosis, psoriasis, rheumatoid arthritis, scleroderma/systemic sclerosis, Sjogren's syndrome, systemic lupus erythematosus, certain thyroiditis, certain uveitis, vitiligo, multiple vasculitis (Wegener)); autoimmune disorders including, but not limited to, granulomatosis; hematopoietic tumors including but not limited to acute and chronic leukemia, lymphoma, multiple myeloma and myelodysplastic syndrome; tumors of the prostate, breast, lung, colon, uterus, skin, liver, bone, pancreas, ovary, testis, bladder, kidney, head, neck, stomach, cervix, rectum, larynx, or esophagus solid tumors; HIV (human immunodeficiency virus) related disorders, RSV (respiratory syncytial virus) related disorders; EBV (Epstein-Barr virus) related disorders; CMV (cytomegalovirus) related disorders; and infectious diseases including, but not limited to, adenovirus-related disorders and BK polyomavirus-related disorders.
Cancers that can be treated with the engineered cells (e.g., CAR T-cells) of the present disclosure, populations thereof, or compositions thereof include blood cancers. In some embodiments, the cancer treated using the engineered cells (e.g., CAR T-cells) described herein, populations thereof, or compositions thereof is a hematologic malignancy or leukemia. In some embodiments, the engineered cells (e.g., CAR T-cells) described herein, populations thereof, or compositions thereof are used for the treatment of acute lymphoblastic leukemia (ALL) or diffuse large B-cell lymphoma (DLBCL). In some embodiments, the cancer is acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), myelodysplasia, myelodysplastic syndromes, acute T-lymphoblastic leukemia, or acute promyelocytic leukemia, chronic myelomonocytic leukemia, or myeloid blast crisis of chronic myeloid leukemia. Examples of cancers treatable using the engineered cells (e.g., CAR T-cells) described herein include, without limitation, breast cancer, ovarian cancer, esophageal cancer, bladder or gastric cancer, salivary duct carcinoma, salivary duct carcinomas, adenocarcinoma of the lung or aggressive forms of uterine cancer, such as uterine serous endometrial carcinoma. In some other embodiments, the cancer is brain cancer, breast cancer, cervical cancer, colon cancer, colorectal cancer, endometrial cancer, esophageal cancer, leukemia, lung cancer, liver cancer, melanoma, ovarian cancer, pancreatic cancer, rectal cancer, renal cancer, stomach cancer, testicular cancer, or uterine cancer. In yet other embodiments, the cancer is a squamous cell carcinoma, adenocarcinoma, small cell carcinoma, melanoma, neuroblastoma, sarcoma (e.g., an angiosarcoma or chondrosarcoma), larynx cancer, parotid cancer, biliary tract cancer, thyroid cancer, acral lentiginous melanoma, actinic keratoses, acute lymphocytic leukemia, acute myeloid leukemia, adenoid cystic carcinoma, adenomas, adenosarcoma, adenosquamous carcinoma, anal canal cancer, anal cancer, anorectum cancer, astrocytic tumor, bartholin gland carcinoma, basal cell carcinoma, biliary cancer, bone cancer, bone marrow cancer, bronchial cancer, bronchial gland carcinoma, carcinoid, cholangiocarcinoma, chondrosarcoma, choroid plexus papilloma/carcinoma, chronic lymphocytic leukemia, chronic myeloid leukemia, clear cell carcinoma, connective tissue cancer, cystadenoma, digestive system cancer, duodenum cancer, endocrine system cancer, endodermal sinus tumor, endometrial hyperplasia, endometrial stromal sarcoma, endometrioid adenocarcinoma, endothelial cell cancer, ependymal cancer, epithelial cell cancer, Ewing's sarcoma, eye and orbit cancer, female genital cancer, focal nodular hyperplasia, gallbladder cancer, gastric antrum cancer, gastric fundus cancer, gastrinoma, glioblastoma, glucagonoma, heart cancer, hemangioblastomas, hemangioendothelioma, hemangiomas, hepatic adenoma, hepatic adenomatosis, hepatobiliary cancer, hepatocellular carcinoma, Hodgkin's disease, ileum cancer, insulinoma, intraepithelial neoplasia, interepithelial squamous cell neoplasia, intrahepatic bile duct cancer, invasive squamous cell carcinoma, jejunum cancer, joint cancer, Kaposi's sarcoma, pelvic cancer, large cell carcinoma, large intestine cancer, leiomyosarcoma, lentigo maligna melanomas, lymphoma, male genital cancer, malignant melanoma, malignant mesothelial tumors, medulloblastoma, medulloepithelioma, meningeal cancer, mesothelial cancer, metastatic carcinoma, mouth cancer, mucoepidermoid carcinoma, multiple myeloma, muscle cancer, nasal tract cancer, nervous system cancer, neuroepithelial adenocarcinoma nodular melanoma, non-epithelial skin cancer, non-Hodgkin's lymphoma, oat cell carcinoma, oligodendroglial cancer, oral cavity cancer, osteosarcoma, papillary serous adenocarcinoma, penile cancer, pharynx cancer, pituitary tumors, plasmacytoma, pseudosarcoma, pulmonary blastoma, rectal cancer, renal cell carcinoma, respiratory system cancer, retinoblastoma, rhabdomyosarcoma, sarcoma, serous carcinoma, sinus cancer, skin cancer, small cell carcinoma, small intestine cancer, smooth muscle cancer, soft tissue cancer, somatostatin-secreting tumor, spine cancer, squamous cell carcinoma, striated muscle cancer, submesothelial cancer, superficial spreading melanoma, T cell leukemia, tongue cancer, undifferentiated carcinoma, ureter cancer, urethra cancer, urinary bladder cancer, urinary system cancer, uterine cervix cancer, uterine corpus cancer, uveal melanoma, vaginal cancer, verrucous carcinoma, VIPoma, vulva cancer, well-differentiated carcinoma, or Wilms tumor.
In some embodiments, the present disclosure provides methods of treating a subject in need of treatment by administering to the subject a composition comprising any of the engineered cells described herein. As used, the terms “treat,” “treatment,” and the like refer generally to obtaining a desired pharmacological and/or physiological effect. That effect is preventive in terms of complete or partial prevention of the disease and/or therapeutic in terms of partial or complete cure of the disease and/or adverse effects resulting from the disease. The term “treatment”, as used herein, encompasses any treatment of a disease in a subject (e.g., mammal, e.g., human). Treatment may also refer to the administration of the engineered cells provided herein to a subject that is susceptible to the disease but has not yet been diagnosed as suffering from it, including preventing the disease from occurring; inhibiting disease progression; or reducing the disease (i.e., causing a regression of the disease). Further, treatment may stabilize or reduce undesirable clinical symptoms in subjects (e.g., patients). The cells provided herein populations thereof, or compositions thereof may be administered before, during or after the occurrence of the disease or injury.
In certain embodiments, the subject has a disease, condition, and/or injury that can be treated and/or ameliorated by cell therapy. In some embodiments, the subject in need of cell therapy is a subject having an injury, disease, or condition, thereby causing cell therapy (e.g., therapy in which cellular material is administered to the subject). However, it is contemplated that it is possible to treat, ameliorate and/or reduce the severity of at least one symptom associated with the injury, disease or condition. In certain embodiments, a subject in need of cell therapy includes, but is not limited to, a bone marrow transplant or stem cell transplant candidate, a subject who has received chemotherapy or radiation therapy, a hyperproliferative disease or cancer (e.g., a hematopoietic system), a subject having or at risk of developing a hyperproliferative disease or cancer), a subject having or at risk of developing a tumor (e.g., solid tumor), viral infection or virus. It is also intended to encompass subjects suffering from or at risk of suffering from a disease associated with an infection.
In some embodiments, the present disclosure provides a composition of the present disclosure along with instructions for use. The instructions for use can be present in the kits as a package insert, in the labeling of the container of the kit or components thereof, or can be in digital form (e.g. on a CD-ROM, via a link on the internet). A kit can include one or more of a genome-targeting nucleic acid, a polynucleotide encoding a genome-targeting nucleic acid, a site-directed polypeptide, and/or a polynucleotide encoding a site-directed polypeptide. Additional components within the kits are also contemplated, for example, buffer (such as reconstituting buffer, stabilizing buffer, diluting buffer), and/or one or more control vectors.
6. Combination Therapies
In some embodiments, an engineered cells of the present disclosure or composition thereof is administered with at least one additional therapeutic agent. Any suitable additional therapeutic agent may be administered with an engineered cell provided herein, populations thereof, or compositions thereof. In some aspects, the additional therapeutic agent is selected from radiation, an ophthalmologic agent, a cytotoxic agent, a chemotherapeutic agent, a cytostatic agent, an anti-hormonal agent, an immunostimulatory agent, an anti-angiogenic agent, and combinations thereof.
In some embodiments, an engineered cell of the present disclosure or composition thereof is administered with a steroid. The administration of a steroid can prevent or mitigate the risk of a subject receiving the engineered cell(s) or composition thereof having an autoimmune reaction.
The additional therapeutic agent may be administered by any suitable means. In some embodiments, the engineered cells described herein, populations thereof, or compositions thereof and the additional therapeutic agent is administered in the same pharmaceutical composition, e.g. by infusion. In some embodiments, the engineered cells described herein and additional therapeutic agent are included in different pharmaceutical compositions.
The pharmaceutical composition may comprise one or more pharmaceutical excipients. Any suitable pharmaceutical excipient may be used, and one of ordinary skill in the art is capable of selecting suitable pharmaceutical excipients. Accordingly, the pharmaceutical excipients provided below are intended to be illustrative, and not limiting. Additional pharmaceutical excipients include, for example, those described in the Handbook of Pharmaceutical Excipients, Rowe et al. (Eds.) 6th Ed. (2009), incorporated by reference in its entirety.
Various modes of administering the additional therapeutic agents are contemplated herein. In some embodiments, the additional therapeutic agent is administered by any suitable mode of administration. Generally, modes of administration include, without limitation, intravitreal, subretinal, suprachoroidal, intraarterial, intradermal, intramuscular, intraperitoneal, intravenous, nasal, parenteral, topical, pulmonary, and subcutaneous routes.
In embodiments where the engineered cells provided herein and the additional therapeutic agent are included in different pharmaceutical compositions, administration of the engineered cells provided herein can occur prior to, simultaneously, and/or following, administration of the additional therapeutic agent.

EXAMPLES

The following are examples of methods and compositions of the invention. It is understood that various other embodiments may be practiced, given the general description provided herein.
Below are examples of specific embodiments for carrying out the present invention. The examples are offered for illustrative purposes only, and are not intended to limit the scope of the present invention in any way. Efforts have been made to ensure accuracy with respect to numbers used (e.g., amounts, temperatures, etc.), but some experimental error and deviation should, of course, be allowed for.
The practice of the present invention will employ, unless otherwise indicated, conventional methods of protein chemistry, biochemistry, recombinant DNA techniques and pharmacology, within the skill of the art. Such techniques are explained fully in the literature. See, e.g., T. E. Creighton, Proteins: Structures and Molecular Properties (W.H. Freeman and Company, 1993); A. L. Lehninger, Biochemistry (Worth Publishers, Inc., current addition); Sambrook, et al., Molecular Cloning: A Laboratory Manual (2nd Edition, 1989); Methods In Enzymology (S. Colowick and N. Kaplan eds., Academic Press, Inc.); Remington's Pharmaceutical Sciences, 18th Edition (Easton, Pennsylvania: Mack Publishing Company, 1990).

Example 1: Identification of Knock-In Loci in Coding Regions

The objective of the experiments in this set of examples was to identify T-cell knock-in (KI) loci in coding regions outside of the T Cell Receptor Alpha Constant (TRAC) locus. To select candidate loci, the criteria and requirements shown in Table 1 were used.

TABLE 1

Criteria used for identification of candidate knock-in loci
within coding regions

	Detailed	Datasets Considered for
Criteria	Requirements	identification of loci

KI	High expression at	Knock in efficiency
efficiency	d2 (day 2)	data on ~90 genes
	Similar expression	derived from
	dynamics as TRAC	Roth, T. L., et al. 2019.
	(stable expression	(Rapid discovery of synthetic
	upon activation)	DNA sequences to rewrite endogenous
	Accessible	T cell circuits. bioRxiv, 604561.)
	chromatin	Bulk RNA-seq data at do, d2, d3 and d4:
	gRNA editing	(i) publicly available data;
	efficiency	(ii) data derived from Roth,
		T. L., et al. 2019.
		(Rapid discovery of synthetic
		DNA sequences to rewrite
		endogenous T cell circuits.
		bioRxiv, 604561.); and
		(iii) internally generated data
		Bulk ATAC-seq data
		at do, d2, d3 and d4:
		(i) data derived from Roth,
		T. L., et al. 2019.
		(Rapid discovery of
		synthetic DNA sequences
		to rewrite endogenous T cell
		circuits. bioRxiv, 604561.); and
		(ii) internally generated data
Safety	Does not affect	T cell screening data
	proliferation,	Achilles' project on cancer cell lines data
	cytolytic activity or	Annotated oncogenes and tumor
	signaling of T cells	suppressors from TCGA
		Annotated functions in immune cells
	Be careful with
	tumor suppressors
	and oncogenes

Generally, the requirements for candidate KI loci within the coding regions was that the coding gene is not essential for T cell function or the knock-out of that gene would be beneficial to chimeric antigen receptor therapy (CAR T) functions.
As shown in Table 1, some of the data utilized, for comparison purposes, to identify candidate KI loci was sourced, in part, from Roth, T. L., et al. 2019 (Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits. bioRxiv, 604561), the relevant disclosures of which are herein incorporated by reference in their entirety. A summary of data in the Roth, T. L. et al. paper is shown in FIG. 3 .
FIG. 4A and FIG. 4B show the processed RNA-seq data, showing that samples cluster based on activation status and by cell type. Donor 4 (AKI4) was identified as an outlier, as it clustered differently than the others, and was removed from remaining analysis. The transcript expression data from RNA-seq experiments on the 90 genes cited in the Roth, T. L. et al. paper was correlated to transcript expression data in Roth, T. L. et al. paper. (See FIG. 5A and FIG. 5B).
FIG. 6 shows the process ATAC-seq data, which focused on the 10 kb area around the transcription start site (TSS). Again, donor 4 (AK14) was identified as an outlier, based on expression profile in both CD4 and CD8 cells, and was removed from remaining analysis. The results of the remaining ATAC-seq analysis are shown in FIGS. 7A-8 . The data in FIG. 7A for TSS enrichment scores also indicated that all libraries were high quality. The data on open chromatin regions around the TRAC locus revealed the highest signal near exon 3 rather than exon 1 (FIG. 8 ).

Determination of Knock-In Efficiency:

The K1 efficiency results (obtained using the model described infra) based on the 5 donors, 2 gRNA, and 2 replicates/gRNAs from the Roth, T. L. et al. paper are shown in FIG. 9 and FIG. 10 .
A linear model was built to estimate KI efficiency of approximately 90 genes using RNA-seq and ATAC-seq data. The linear model captured 33% of the variation in the data (i.e. R²=0.33). FIG. 11 shows KI efficiency versus day 2 (d2) RNA-seq data, day 4 (d4) RNA seq data, and d2 ATAC data. The linear model was applied to remaining candidate genes to estimate their KI efficiency.
The candidate coding loci were selected by first ranking all genes in the pooled data sets by predicted KI efficiency, using RNA-seq expression data from d2 (day 2). Candidate coding loci were required to be stably expressed during T cell activation (e.g., <=2-fold expression change relative to day 0 (d0). The candidate loci also had to be accessible based on ATAC-seq data. Using that selection process/requirements, 16 well-characterized coding genes (with known functions) were selected as candidate genes. The knockout of these 16 would confer a benefit to the function of CART cells (e.g. B2M, CD5, SMAD2, PTPRC, CD3E). An additional 12 coding genes with high predicted KI efficiency and no apparent essential function (inert coding genes) were selected as candidate genes. (See Table 2).

TABLE 2

KI Candidate Loci selected

	Genes with Known Functions	Inert Coding Genes

B2M (~70%)	CD2	SUB1
CD3E (~50%)	SMAD2	EDF1
PTPRC (~50%)	SLC38A1	CAPNS1
CD3G (~30%)	TIGIT	SRP14
	SOCS1 PTPN2	RTRAF APRT
Tested in Roth, T.L. et al	CBLB	PTPRCAP
paper (reported editing	PTEN	SRSF9
efficiency from Roth,	PTPN6	FTL
T.L. et al paper)	CD5	TRIM28
	TET2	SERF2
	TRAC	RPS23

Example 2: Identification of Knock-In Loci in Gene Deserts

The criteria for selection of candidate loci in non-coding regions or gene deserts is summarized in Table 3.

TABLE 3

Criteria used for identification of candidate knock-in loci within
non-coding regions

		Datasets Considered for
Criteria	Detailed Requirements	identification of loci

KI	Accessible chromatin	Bulk ATAC-seq data
efficiency		at d0, d2, d3 and d4:
		(i) data derived from
		Roth, T. L., et al. 2019.
		(Rapid discovery of synthetic
		DNA sequences to rewrite
		endogenous T cell circuits.
		bioRxiv, 604561.); and
		(ii) internally generated data
Safety	>10 kb from cancer-related	Ensembl genes
	genes or TADS	Annotated oncogenes and tumor
	>10 kb from any	suppressors from TCGA
	miRNA/functional small	Annotated enhancers
	RNAs	from Encode and papers
	>10 kb from any 5' gene
	end
	>10 kb from any regulatory
	regions (ultra-conserved
	elements, enhancers)

To select candidate regions within the non-coding regions, the inventors here started by looking in highly accessible regions of the genome (10 kb windows). The most accessible region overlapped with (i) annotated protein coding genes (>50% accessible regions), (ii) pseudogenes and noncoding RNAs (˜20% accessible regions), and (iii) enhancer/regulatory regions (˜20% accessible regions). The candidate genes were required to be <10 kb from the coding regions. A few regions that overlapped with long intergenic noncoding RNAs (lincRNAs) but did not have apparent function in T cells were also considered.
Examples of other criteria that have been used in the art for selection of SHS are described, for example in Pellenz, S., et al. (2019). New human chromosomal sites with “safe harbor” potential for targeted transgene insertion. Human gene therapy, 30(7), 814-828, the relevant disclosures of which are herein incorporated by reference in their entirety.
FIG. 12 is a plot showing the normalized ATAQ SEQ data for a top candidate non-coding region.
Using the above-described selection process/requirement, 11 candidate regions in gene deserts were selected. In total, there were 39 KI candidate loci, including those in coding and non-coding regions that would be evaluated as safe harbor loci (predicted loci).

Example 3: Experimental Evaluation of Predicted Loci

Materials

- 120 sgRNAs were ordered from Synthego, 3 sgRNAs per region, and editing efficiency was assessed by next generation sequencings (NGS).
  - 87 targeted coding genes
  - 33 targeted gene deserts
- 189 constructs were synthesized by Genscript
  - Homology arm: 450 bp each
  - eGFP was used as the reporter
  - Vector backbone: pUC57-Kan backbone
  - 78 with endogenous promoters
  - 111 with EF1a-HTLV promoter
- Constructs were sequence verified by Genscript and majority were internally verified by sequencing. The sgRNA sequences are provided in Table 4 and the construct sequences are provided in Table 5.

Methods
To evaluate the effectiveness of the predicted loci, the following were used:

- (87 endogenous constructs+120 exogenous construct)*2=414 wells+Controls=460
- 3 donors, 2 replicates at 3 time points: wk 1 (d6=day 6), wk 3 (d21=day 21) and wk 4 (d28=day 28)
- Controls
- DNA-only (no ribonucleoprotein (RNP)): episomal expression (n=8)
- DNA+non-targeting guides+RNP: to check if DNA delivery is more efficient with RNP (n=8)

pMax GFP was measured to check if transfection is ok (n=3).
WT cells with no electroporation
WT cells with electroporation
Controls were spread out across plates.
Cells were electroporated without RNP/HDR to check if cell counting makes sense.
2 more donors were added and changed to 3 replicates at 1 time point: wk 1 (d6)
FACS panel: GFP, TCR, Zombie
Washed every 3 wells.
The secondary data collected included: RNA-seq data: at d0, d2, and d4 (to determine stable expression) and ATAC-seq data: at d2 (to identify activated cells). The methods used for conducting the RNA-seq and ATAC-seq experiments are in Roth, T. L., et al. 2019. (Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits. bioRxiv, 604561), which is herein incorporated by reference in its entirety.
Automated gating was performed on FACS data, using .fcs files. For constructs with endogenous promoters, all 5 donors and all 3 time points were used. For constructs with EF1a promoter, used 3 donors (donors 1-3) and 2 time points (wk 3 and wk 4).
To summarize data, wells with a % K1 efficiency (% GFP_high cells)<=10% (likely a gating error, experimental error or minimal integration) were removed. Loci were then ranked by median expression among donors and median % K1 efficiency among donors.
Loci significance was calculated using robust rank aggregation, which was the methodology used for consistent ranking of loci among donors and time points. Methods for conducting robust rank aggregation are known in the art. (See, for example, Kolde, R., et al. (2012). Robust rank aggregation for gene list integration and meta-analysis. Bioinformatics (Oxford, England), 28(4), 573-580, the disclosure of which is herein incorporated by reference in its entirety).
Results
The results from the analysis of controls and experimental groups is shown in FIGS. 13A-25 .
The results of the pmax_GFP control experiments revealed that donor 5 had significantly higher cell count than other donors. Generally, the GFP_high readings decreased over time, as expected. (FIGS. 13A and 13B).
Experiments to analyze non-targeting controls for changes in episomal GFP expression, revealed that episomal GFP expression decreased to less than 0.05 over time. (FIGS. 14A and 14B) Some of the outliers were attributed to gating errors, which were most severe in donor 3. WT control experiments also exhibited <0.05 GFP_high readings, as expected (FIG. 15 ).
As shown in FIG. 16 and FIG. 17 , there was a more consistent trend among donors when using sgRNAS to target the B2M safe harbor locus.
A comparison of GFP expression trends between sgRNA79 and sgRNA83 for TRAC insertion and expression with an endogenous reporter revealed that donor 2 trends were different between sgRNA79 and sgRNA83, while donor 4 trends were the same (FIG. 18 and FIG. 22 ). Some potential reasons for the observed variation between replicates and donors include:

- (1) manual handling of a large number of plates (e.g., FIG. 26 ):
  - Edge effects
  - Electroporation errors
- (2) Inherent differences among donors (e.g., FIG. 27 ):
  - There were consistent differences with certain wells throughput the assay (spanning multiple weeks)
  - There were variable cell numbers between donors
- (3) Gating errors (e.g. FIG. 28 ):
  - 1 peak vs >2 peaks in GFP signals

Example 4: Ranking Loci by Expression and KI Efficiency

The loci were ranked based on mean florescence intensity (MFI) of reporter gene, GFP, and KI efficiency.
FIG. 29 shows GFP MFI and KI efficiency for all significant loci having endogenous promoters. The B2M locus reported the highest GFP MFI. The TRAC locus was among the top 10 MFI. The highest GFP MFI readings were reported in week 1 and reduced slightly in weeks 3 and 4. The results also showed most top loci have more than 1 sgRNA. With regard to KI efficiency, the SOCS1 locus reported the highest KI efficiency. Overall, KI efficiency showed greater variation among donors than GFP MFI.
FIG. 30 shows GFP MFI and KI efficiency for all significant loci having exogenous promoters (e.g. EF1a promoters). The TRAC locus reported the highest GFP MFI. There was comparable expression between weeks 3 and 4. The results also showed most top loci have more than 1 sgRNA. With regard to KI efficiency, the SOCS1 locus reported the highest KI efficiency. Overall, KI efficiency showed less variation when driven by the exogenous promoters than when driven by endogenous promoters.
FIGS. 31A, 31B, and 31C show GFP MFI and KI efficiency for all significant loci having endogenous and exogenous (e.g., EF1a) promoters. The results showed that expression driven by EF1a promoters is about 10× higher than endogenous promoters (FIG. 31A). With regard to KI efficiency, the SOCS1 locus reported the highest KI efficiency. At weeks 3 and 4, KI efficiency was higher when driven by the exogenous promoters than when driven by endogenous promoters.

Example 5: Evaluation of TCR Expression in Candidate Noncoding Sites

This experiment was conducted to identify target loci and integration sites that enable high transgene expression without disrupting the TCR. Some gene deserts ( e.g. gene deserts 2, 3, 5, and 6) were identified as having high transgene expression (FIG. 32A).
To evaluate and identify preferred knock-in sites, TCR expression was measured following circuit cassette knock in of PrimeR (Prime Receptor (Myc)). Myc denotes an N-terminal Myc epitope tag to facilate detection of surface expressed primer receptor. Briefly, CD3-CD28 Dynabead-activated T cells were electroporated with sgRNA/Cas9 RNPs targeting the indicated sites (see FIGS. 32B and 33A), as well as HDRTs with homology arms directing HDR-mediated integration into the indicated sites. At day 6 post-electroporation, cells were stained with anti-TCRalpha/beta and anti-myc antibodies and analyzed on an Attune NxT flow cytometer. As shown in FIG. 32B, the TCR expression was maintained at GS94 and GS102 candidate integration (knock-in) sites. Only ⅔ of the cells that had circuit cassette knock in of PrimeR at GS79 (TRAC) locus maintained TCR expression. These results indicated that the GS94 and GS102 sites showed better potential for TCR stimulation.
The percentage of cells showing effective knock-in (based on measurements of PrimeR) was 36%±4% when using the GS94 integration site, as compared to 32%±5% when using the TRAC integration site. These results revealed integration sites, including GS94, that supported reproducibly high circuit cassette knockin rates. See FIG. 33A.

Example 6: Evaluation of GS94 Circuit Expression and Function

GS94 is a candidate integration site located on chromosome 11's distal q arm. It is within 180-350 kb of the promoters for ETS1 and FLI1 (FIG. 33B), however that is considered low-risk for integration vector gene therapy. The circuit expression and function potential of the GS94 gene was evaluated.
T cells underwent circuit cassette integration with PrimeR at GS79 (TRAC) integration site and GS94 integration site. The cells were cocultured with K562 C19 cells for 48 hours and then the PrimeR induced CAR MFI was compared to the PrimeR MFI.
Briefly, T cells generated as described in the Example above were cocultured with K562 CD19+/MSLN− cells at day 7 post-electroporation. MSLN (mesothelin) is a gene that is overexpressed in human pancreatic cancer. Cells were then stained with anti-FLAG antibody 48 h post initiation of coculture and analyzed on an Attune NxT flow cytometer. The results revealed that GS94 yields superior CAR induction with high prime R expression following the 48-hour coculture with the K562 C19 cells. See FIG. 34A. GS94 resulted in prime antigen-dependent CAR expression that was approximately two-fold higher than the expression in several other candidate integration sites as well as the TRAC integration site. Additionally, on average, the prime receptor surface expression level was no less than 50% of expression level when using the TRAC integration site.

Cytotoxicity and Cytokine Secretion

To evaluate the effect of the candidate integration site on cytotoxicity and cytokine secretion, T cells that had undergone circuit cassette integration with PrimeR at GS79 (TRAC) integration site and GS94 integration site were cocultured with K562 C19/MSLN cells for 48 hours. MSLN is a gene that is overexpressed in human pancreatic cancer. The cells were treated at a 1:1 effector:target cell ratio (1:1 E:T)). Briefly, T cells generated as described above were cocultured with K562 CD19+/MSLN+ cells at day 7 post-electroporation. 48 h post initiation of coculture, supernatants were collected and analyzed via Luminex® for cytokine levels. The cytokines measure were IL-2, INFg, and TNF. Cytotoxicity was analyzed by measuring luciferase activity of remaining target cells after 48 h. Each of the data points in FIG. 34B represent two replicates and the lines represent the range of cytotoxicity for the replicates. As shown in FIG. 34B, the GS94 integration sites resulted in superior cycotoxic ability and cytokine secretion following the 48-hour coculture with K562 C19/MSLN cells.

Prime-Independent Cytotoxicity

To compare the effect of the candidate integration site on cytotoxicity versus prime-independent cytotoxicity, T cells that had undergone circuit cassette integration with PrimeR at GS79 (TRAC) integration site and GS94 integration site were cocultured with K562 CD19+/MSLN+ cells or K562 CD19−/MSLN+ cells (“K562 MSLN”) at day 7 post-electroporation for 48 hours. 0.3, 1.0, and 3.0 E:T cell ratios were tested. See FIG. 35A and FIG. 35B. At 48 h post initiation of coculture, cytotoxicity was analyzed by measuring luciferase activity of remaining target cells As shown in FIG. 35B, the GS94 integration site resulted in equivalent cytotoxic potential to the TRAC integration site and there was no prime-independent cytotoxicity.

Prime-Independent Cytokine Section

To compare the effect of the candidate integration site on cytoxicity versus prime-independent cytotoxicity, T cells that had undergone circuit cassette integration with PrimeR at GS79 (TRAC) integration site and GS94 integration site, generated as described above, were cocultured with K562 CD19+/MSLN+ cells. A group that had target cells only (E:T=0; Targets only) was compared to a group with an E:T cell ratio of 1. Following the 48 h coculture with the K562 CD19+/MSLN+ cells, supernatant was collected and analyzed via Luminex® for cytokine levels to measure secretion of IL-2, INFg and TNF cytokines. See FIG. 36A and FIG. 36B. As shown in FIG. 36B, the GS94 integration site resulted in equivalent cytokine secretion to the TRAC integration site and there was no prime-independent secretion of IL-2, INFg or TNF.

Prime-Independent CAR Expression

To evaluate the effect of the candidate integration site on prime-independent CAR expression, T cells that had undergone circuit cassette integration with PrimeR at GS79 (TRAC) integration site, GS94 integration site, and GS102 integration site were cultured in vitro for 32 days. The cells were treated with repetitive CD3/CD28 stimulation at days 5, 12, 19 and 28 of the experiment. On Day 16, the cells were evaluated for CAR expression using a flow cytometry assay. As shown in FIG. 37 , T cell activation through TCR did not result in prime R-independent CAR expression from circuit cassette integration at the candidate integration sites.
T cells generated as described above were cultured in 96-well plates, with T cell growth medium being exchanged every 2 days. At days 5, 12, 19 and 28, T cells were stimulated with 1:1 CD3/CD28 Dynabeads. Cells were analyzed for PrimeR expression by myc epitope tag staining, and for CAR expression by FLAG epitope tag staining at the indicated time points. Flow analysis was performed on an Attune NxT flow cytometer.

Example 7: Evaluating Stability of Prime Receptor Expression Over Several Weeks

To evaluate the effect of the candidate integration sites on stable (sustained) expression of PrimeR, T cells that had undergone circuit cassette integration with PrimeR at the integration sites indicated in FIG. 38 were cultured in vitro for 32 days. Briefly, T cells generated as described above were cultured in 96-well plates, with T cell growth medium being exchanged every 2 days. At days 5, 12, 19 and 28, T cells were stimulated with 1:1 CD3/CD28 Dynabeads repetitive stimulation. Flow cytometry assays were run on days 16 and 32 using an Attune NxT flow cytometer. The cells were analyzed for PrimeR expression by myc epitope tag staining. As shown in FIGS. 38A and 38B, the GS94 integration site resulted in stable PrimeR expression over at least a 4-week period.

Example 8: Evaluation of On-Target Editing Efficiency

To evaluate the on-target editing efficiency of candidate knock-in sites, iGUIDE-Seq assay was used. The methods used for conducting the iGUIDE-Seq assay are illustrated in FIG. 39A and provided in Nobles et al., Genome Biology (2019), which is hereby incorporated by reference in its entirety. As shown in FIG. 39B, the GS94 integration site had the highest on-target editing efficiency of the evaluated candidate integration sites. As shown in FIG. 39C, GS94 resulted in no putative off-target editing as observed with two donors.

Example 9: Evaluation of GS94 Knock-In

Methods

Elevation prediction: Computational predictions of potential off-target sites from (gs94) were performed using Elevation-search (algorithm described in Listgarten et al. 2018. Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs. Nat Biomed Engr 2, 37-48; software obtained from github.com/Microsoft/Elevation). All sites identified by Elevation-search were subjected to analysis using rhAmp-seg™.
rhAmpSeg™: 49 candidate off-target sites for GS94 identified by iGUIDE or the Elevation prediction algorithm and the GS94 target site were characterized by rhAmpSeg™ (Integrated DNA Technologies, Inc.). This targeted amplification enables NGS-based quantification of the editing occurring at numerous sites simultaneously. Genomic DNA from T cells from at least 2 donors that had been treated singly with each of the following 7 guides: GS84, GS94, GS95, GS96, GS102, GS108, and GS138 was isolated with the GenFind® V3 DNA purification system (Beckman Coulter). Two separate rhAmpSeg™ amplification pools were used to cover the 50 loci, the procedure was performed as recommended by Integrated DNA Technologies for each of the samples. The rhAmpSeg™ libraries were sequenced on a MiniSeg™ with a Mid Output Kit (300-cycles) (Illumina). The CRISPResso2 algorithm (github.com/pinellolab/CRISPResso2) was used to determine the percentage of insertions and deletions at each of the amplified loci. Statistical significance (FDR-adjusted p-value≤0.001) using a chi-squared test was only observed at the GS94 site.
RNA-seq: To evaluate changes induced by GS94 integration at the transcriptional level, a CD19/MSLN circuit was integrated at the GS79 (TRAC), GS94, and GS102 integration sites. On day 6 post-integration, 1e6 edited cells were sorted using a BD FACSAria based on transgene expression. RNA was isolated from sorted T cells with the RNeasy kit (Qiagen). Purified RNA was converted into an NGS library using the TruSeq™ RNA Library Prep Kit v2 (Illumina). Libraries were sequenced on either the NovaSeq™ 6000 or NextSeq™ 550 instruments (Illumina). The STAR 2.7.3a aligner (Dobin A. et al. Bioinformatics. 2013. 29:15-21) was used to align the RNA-seq data against the reference human GRCh38 transcriptome and to obtain gene-level read counts. edgeR (Robinson M D et al. Bioinformatics. 2010. 26: 139-140) was used to compute differential expression, combining data across both donors. The only genes within 300 Kb of the GS94 site, ETS1 and FLI1, were not differentially expressed in cells with integration at the GS94 integration site compared to cells with integration at any of the other two loci. At an FDR-adjusted p-value cutoff of 0.01, the number of differentially expressed genes was minimal (<100 genes genome-wide).
Cytokine-independent growth assay: To evaluate the safety of the primary T cells with GS94 locus KI, cytokine-independent growth assay was performed to evaluate the potential for oncogenic transformation. Briefly, primary human T cells that had undergone CD19/MSLN circuit cassette integration at GS94 locus were thawed and recovered overnight. 1×10⁶cells were then seeded in one well of a 24 well-GRex plate, culturing for 5 days in the medium with or without cytokines. Cell number and viability were recorded at days 0, 3 and 5. As a positive control, 1×10⁶Jurkat cells were cultured in the medium without cytokines in parallel. As shown in FIG. 43 , while GS94 KI T cells maintained good viability and total cell count when cultured with cytokine, the viability of GS94 KI T cells drastically decreased over the course of 5 days when cultured without cytokine and there was no viable cell left on day 5. The positive control Jurkat cells maintained good viability and expansion without cytokine throughout the assay. Taken together, this data shows that GS94 edited primary human T cells still depend on exogenous cytokine for growth, survival and expansion, therefore, there is no concern for cellular transformation.

Results

The specificity of CRISPR reagents (e.g. SpCas9 complexed with sgRNA) targeting candidate loci including GS94 was evaluated by iGUIDE-seq (FIG. 40 ). GS94-targeting CRISPR RNP showed the highest percentage of iGUIDE-seq oligo cassette trapping events of all candidates evaluated, and the control sgRNA sequences from the iGUIDE-seq paper showed similar specificities to what was reported in the original publication, suggesting that the assay performed as expected.
Putative off-target sites were taken from the iGUIDE-seq output, which already suggested that the putative sites were spurious. Additional target sites were predicted by a computational approach (Elevation software package). rhAmp-seg™ was used to prepare high-throughput sequencing libraries for each of the putative off-target sites, and the method was applied to DNA samples from T cells electroporated with CRISPR RNPs targeting the candidate target sites. The resulting NGS data were processed with CRISPResso2 software, and the frequency of insertions and deletions (indels) was taken as indication of CRISPR cleavage activity, as is common in the field. T cells electroporated with GS94-targeting CRISPR RNP showed no greater frequency of indels at the set of putative off-target sites than T cells treated with CRISPR RNP targeting other sites, consistent with the GS94-targeting CRISPR RNP having no consequential or detectable off-target activity, and therefore being the most specific out of the set evaluated (FIG. 41 ).
Potential effects of transgene integration at the GS94 site on the regulation of the T cell transcriptome were evaluated by knocking in a large cassette to the site, growing T cells for several days, sorting cells expressing the transgene within the cassette, and then collecting RNA from the cells. RNA-seq libraries were prepared and sequenced, and analysis of the resulting Illumina sequencing data revealed no biologically or statistically significant differences in expression of any genes within 300 kb of the GS94 site in cells with integrations at GS94 compared to cells with integration at TRAC or the GS102 sites (FIG. 42 ). Furthermore, other gene expression differences that reached statistical significance were minimal in number and in effect size, consistent with them being noise in the comparison.
To assess whether transgene integration at GS94 could confer a transformed phenotype, cells with integrations at the GS94 site were cultured with and without cytokines in vitro. Cells remained alive and viable with cytokine addition, but died without cytokine supplementation and lost their viability (FIG. 43 ). The positive control Jurkat cells remained viable and proliferated. Overall, this indicates that integration of a transgene at GS94 does not confer capacity for cytokine-independent growth, which is a hallmark of T cell transformation.

Example 10: In Vivo Insertion of a CAR Expressing Cassette

In vivo efficacy of T cells with a transgene cassette expressing a CAR recognizing a tumor antigen, or a CAR recognizing a tumor antigen under control of a priming receptor recognizing an antigen in the anatomical vicinity of the tumor, is assessed against human tumor cells such as K562 engineered to express the CAR antigen or to express antigens recognized by both the priming receptor and the CAR. Tumor cells (e.g. 1e6) are subcutaneously injected into the flank of NSG mice (Jackson Laboratories). Tumor growth is assessed by dimensional measurement by calipers every 2-4 days. When the tumor volume reaches ˜100 cubic mm, mice are intravenously injected with 5e6 T cells with a CAR or prime-CAR circuit cassette integrated at a specific site by CRISPR-mediated insertion, or with T cells engineered with CRISPR RNP alone, or with PBS alone as a sham injection. Tumor growth is monitored and mice are euthanized when tumor volume reaches 2000 cubic mm. Peripheral blood is bled from mice through a retro-orbital procedure, and flow cytometry and/or ddPCR is used to observe engineered T cell expansion over time. At time of sacrifice, spleen, blood, tumor and/or other tissue is analyzed via flow cytometry, ddPCR, and/or immunohistochemistry for the presence of engineered T cells. The results demonstrate that T cells engineered with cassette integration at one of the defined genomic loci lead to tumor regression and clearance in injected mice as compared to T cells without cassette integration, and that engineered T cells are detectable in the peripheral blood and tissues of injected mice.

REFERENCES

Eyquem, J., Mansilla-Soto, J., Giavridis, T., van der Stegen, S. J Hamieh, M., Cunanan, K. M., . . . & Sadelain, M. (2017). Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection. Nature, 543(7643), 113-117.
Sadelain, M., Papapetrou, E. P., & Bushman, F. D. (2012). Safe harbours for the integration of new DNA in the human genome. Nature reviews Cancer, 12(1), 51-58.
Irion, S., Luche, H., Gadue, P., Fehling, H. J., Kennedy, M., & Keller, G. (2007). Identification and targeting of the ROSA26 locus in human embryonic stem cells. Nature biotechnology, 25(12), 1477-1482.
Pellenz, S., Phelps, M., Tang, W., Hovde, B. T., Sinit, R. B., Fu, W., . . . & Monnat Jr, R. J. (2019). New human chromosomal sites with “safe harbor” potential for targeted transgene insertion. Human gene therapy, 30(7), 814-828.
Roth, T. L., Li, P. J., Nies, J. F., Yu, R., Nguyen, M. L., Lee, Y., . . . & Nguyen, D. N. (2019). Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits. bioRxiv, 604561.

TABLE 4

SGRNA SEQUENCES USED FOR EVALUATION OF PREDICTED LOCI

					Median (%
					Modified),
		sgRNA_			summarized
		start_	sgRNA	Integra-	from 2
sgRNA		coor	Target	tion	donors, 2
ID	sgRNA Sequence	GRCH38	Loci	Site	primersets

sgRNA_	GCACCTGAATACCACGCCTG	chr16:	APRT	APRT	79.28
1	(SEQ ID NO: 1)	88811818

sgRNA_	CGCCTGCGATGTAGTCGATG	chr16:	APRT	APRT	78.60
2	(SEQ ID NO: 2)	88811551

sgRNA_	CAGGACGGGCGAGATGTCCC	chr16:	APRT	APRT	85.25
3	(SEQ ID NO: 3)	88811640

sgRNA_	CTGAATCTTTGGAGTACCTG	chr15:	B2M	B2M	78.51
4	(SEQ ID NO: 4)	44715425

sgRNA_	GGCCACGGAGCGAGACATCT	chr15:	B2M	B2M	94.75
5	(SEQ ID NO: 5)	44711550

sgRNA_	AAGTCAACTTCAATGTCGGA	chr15:	B2M	B2M	70.97
6	(SEQ ID NO: 6)	44715515

sgRNA_	GCTTGGAGGCCTGATCAGCG	chr19:	CAPNS1	CAPNS1	89.34
7	(SEQ ID NO: 7)	36141111

sgRNA_	CTTATCTCTTCGCAGCGAGG	chr19:	CAPNS1	CAPNS1	91.09
8	(SEQ ID NO: 8)	36142301

sgRNA_	CACACATTACTCCAACATTG	chr19:	CAPNS1	CAPNS1	71.98
9	(SEQ ID NO: 9)	36142676

sgRNA_	TTCCGCAAAATAGAGCCCCA	chr3:	CBLB	CBLB	91.55
10	(SEQ ID NO: 10)	105746019

sgRNA_	TGCACAGAACTATCGTACCA	chr3:	CBLB	CBLB	91.43
11	(SEQ ID NO: 11)	105751622

sgRNA_	GCAATAAGACTCTTTAAAGA	chr3:	CBLB	CBLB	76.18
12	(SEQ ID NO: 12)	105853470

sgRNA_	CAAAGAGATTACGAATGCCT	chr1:	CD2	CD2	89.80
13	(SEQ ID NO: 13)	116754658

sgRNA_	CAAGGCACCCCAGGTTTCCA	chr1:	CD2	CD2	92.70
14	(SEQ ID NO: 14)	116754663

sgRNA_	TTACGAATGCCTTGGAAACC	chr1:	CD2	CD2	92.82
15	(SEQ ID NO: 15)	116754666

sgRNA_	CAGAGACGCATCTGACCCTC	chr11:	CD3E	CD3E	90.96
16	(SEQ ID NO: 16)	118315540

sgRNA_	CATGCAGTTCTCACACACTG	chr11:	CD3E	CD3E	87.47
17	(SEQ ID NO: 17)	118313715

sgRNA_	GTGTGAGAACTGCATGGAGA	chr11:	CD3E	CD3E	86.65
18	(SEQ ID NO: 18)	118313715

sgRNA_	TCTCATTTCAGGAAACCACT	chr11:	CD3G	CD3G	87.24
19	(SEQ ID NO: 19)	118349748

sgRNA_	AGTCATACACCTTAACCAAG	chr11:	CD3G	CD3G	87.99
20	(SEQ ID NO: 20)	118349754

sgRNA_	TTCAAGGAAACCAGTTGAGG	chr11:	CD3G	CD3G	86.55
21	(SEQ ID NO: 21)	118352458

sgRNA_	GAGCCTTGCCTGGAAATCTG	chr11:	CD5	CD5	84.03
22	(SEQ ID NO: 22)	61118177

sgRNA_	AAGCGTCAAAAGTCTGCCAG	chr11:	CD5	CD5	89.19
23	(SEQ ID NO: 23)	61118324

sgRNA_	CGTTCCAACTCGAAGTGCCA	chr11:	CD5	CD5	83.11
24	(SEQ ID NO: 24)	61118121

sgRNA_	GAGCGACTGGGACACGGTGA	chr9:	EDF1	EDF1	88.84
25	(SEQ ID NO: 25)	136866246

sgRNA_	GCTGCGCAAGAAGGGCCCTA	chr9:	EDF1	EDF1	91.04
26	(SEQ ID NO: 26)	136866211

sgRNA_	TTGTTCTGGCCAGCAGCCCC	chr9:	EDF1	EDF1	85.98
27	(SEQ ID NO: 27)	136863433

sgRNA_	CTTCCAGAGCCACATCATCG	chr19:	FTL	FTL	93.10
28	(SEQ ID NO: 28)	48965791

sgRNA_	GGGACTCACCAGAGAGAGGT	chr19:	FTL	FTL	88.86
29	(SEQ ID NO: 29)	48965601

sgRNA_	CGGTCGAAATAGAAGCCCTA	chr19:	FTL	FTL	93.14
30	(SEQ ID NO: 30)	48965770

sgRNA_	AAAAGGATATTGTGCAACTG	chr10:	PTEN	PTEN	92.37
31	(SEQ ID NO: 31)	87933015

sgRNA_	TGTGCATATTTATTACATCG	chr10:	PTEN	PTEN	90.64
32	(SEQ ID NO: 32)	87933183

sgRNA_	TTTGTGAAGATCTTGACCAA	chr10:	PTEN	PTEN	85.36
33	(SEQ ID NO: 33)	87933087

sgRNA_	TGTCATGCTGAACCGCATTG	chr18:	PTPN2	PTPN2	87.94
34	(SEQ ID NO: 34)	12830972

sgRNA_	CCACTCTATGAGGATAGTCA	chr18:	PTPN2	PTPN2	92.45
35	(SEQ ID NO: 35)	12859219

sgRNA_	TTGACATAGAAGAGGCACAA	chr18:	PTPN2	PTPN2	93.96
36	(SEQ ID NO: 36)	12836828

sgRNA_	GAGTACTACACTCAGCAGCA	chr12:	PTPN6	PTPN6	89.61
37	(SEQ ID NO: 37)	6952098

sgRNA_	TCACGCACAAGAAACGTCCA	chr12:	PTPN6	PTPN6	82.74
38	(SEQ ID NO: 38)	6954872

sgRNA_	AGGTCTCGGTGAAACCACCT	chr12:	PTPN6	PTPN6	91.27
39	(SEQ ID NO: 39)	6951610

sgRNA_	AGCATTATCCAAAGAGTCCG	chr1:	PTPRC	PTPRC	88.88
40	(SEQ ID NO: 40)	198696873

sgRNA_	ATATTAATTCTTACCAGTGG	chr1:	PTPRC	PTPRC	88.95
41	(SEQ ID NO: 41)	198692370

sgRNA_	AGCTTTAAATCAAGGTTCAT	chr1:	PTPRC	PTPRC	96.89
42	(SEQ ID NO: 42)	198756176

sgRNA_	ATCCCGAGCCCTAAGGTGCA	chr11:	PTPRCAP	PTPRCA	84.08
43	(SEQ ID NO: 43)	67436325		P

sgRNA_	GGCAGCGCGGAGGACAGCGT	chr11:	PTPRCAP	PTPRCA	97.74
44	(SEQ ID NO: 44)	67436285		P

sgRNA_	CTCAGGGGGCTACTACCACC	chr11:	PTPRCAP	PTPRCA	91.50
45	(SEQ ID NO: 45)	67436170		P

sgRNA_	GTCACCGACGAGACCAGAAG	chr5:	RPS23	RPS23	79.40
46	(SEQ ID NO: 46)	82277810

sgRNA_	GTCGTGGACTTCGTACTGCT	chr5:	RPS23	RPS23	83.07
47	(SEQ ID NO: 47)	82277843

sgRNA_	TAATTTTTAGGCAAGTGTCG	chr5:	RPS23	RPS23	61.94
48	(SEQ ID NO: 48)	82277860

sgRNA_	TTAGCTGTTAGACTTGAATA	chr14:	RTRAF	RTRAF	85.50
49	(SEQ ID NO: 49)	51993810

sgRNA_	CGAGAGCCGTCAACTTGCGT	chr14:	RTRAF	RTRAF	85.64
50	(SEQ ID NO: 50)	51989652

sgRNA_	CGGCTTCAACTGCAAAGGTG	chr14:	RTRAF	RTRAF	88.77
51	(SEQ ID NO: 51)	51989700

sgRNA_	TATGAAAAAGCAGAGCGACT	chr15:	SERF2	SERF2	89.61
52	(SEQ ID NO: 52)	43793025

sgRNA_	TCTGGCGGGCGAGCTCACGC	chr15:	SERF2	SERF2	86.73
53	(SEQ ID NO: 53)	43792989

sgRNA_	CTCACGCTGGTTACCGCCTA	chr15:	SERF2	SERF2	80.57
54	(SEQ ID NO: 54)	43792977

sgRNA_	AAAGATTACGAACTTCCCTG	chr12:	SLC38A1	SLC38A1	92.24
55	(SEQ ID NO: 55)	46207559

sgRNA_	GTTAAAAACAGACATGCCTA	chr12:	SLC38A1	SLC38A1	91.51
56	(SEQ ID NO: 56)	46229232

sgRNA_	ATGCCTAAGGAGGTTGTACC	chr12:	SLC38A1	SLC38A1	79.48
57	(SEQ ID NO: 57)	46229246

sgRNA_	CTCCAGGTATCCCATCGAAA	chr18:	SMAD2	SMAD2	79.53
58	(SEQ ID NO: 58)	47869418

sgRNA_	CACCAAATACGATAGATCAG	chr18:	SMAD2	SMAD2	86.61
59	(SEQ ID NO: 59)	47870532

sgRNA_	TGGCGGCGTGAATGGCAAGA	chr18:	SMAD2	SMAD2	82.91
60	(SEQ ID NO: 60)	47896729

sgRNA_	TAGGATGGTAGCACACAACC	chr16:	SOCS1	SOCS1	92.25
61	(SEQ ID NO: 61)	11255478

sgRNA_	CAGCAGCAGAGCCCCGACGG	chr16:	SOCS1	SOCS1	83.79
62	(SEQ ID NO: 62)	11255432

sgRNA_	CGGCGTGCGAACGGAATGTG	chr16:	SOCS1	SOCS1	84.24
63	(SEQ ID NO: 63)	11255296

sgRNA_	TATAGACGCTGCCCGACGTC	chr15:	SRP14	SRP14	95.12
64	(SEQ ID NO: 64)	40038895

sgRNA_	TCCAAAGAAGGGTACTGTGG	chr15:	SRP14	SRP14	92.14
65	(SEQ ID NO: 65)	40038368

sgRNA_	ACAGTACCCTTCTTTGGAAT	chr15:	SRP14	SRP14	65.82
66	(SEQ ID NO: 66)	40038358

sgRNA_	GCGACGGGCGCATCTACGTG	chr12:	SRSF9	SRSF9	83.68
67	(SEQ ID NO: 67)	120469572

sgRNA_	CCCGACCTCCATAAGTCCTG	chr12:	SRSF9	SRSF9	92.56
68	(SEQ ID NO: 68)	120465700

sgRNA_	GGGGTCCTCGAAGCGCACGA	chr12:	SRSF9	SRSF9	89.94
69	(SEQ ID NO: 69)	120469426

sgRNA_	TGCTCTGTTTAGAAGATGAC	chr5:	SUB1	SUB1	79.36
70	(SEQ ID NO: 70)	32591641

sgRNA_	ATATTCTTTTCTAGTTAAAG	chr5:	SUB1	SUB1	70.93
71	(SEQ ID NO: 71)	32591566

sgRNA_	CCTGTAAAGAAACAAAAGAC	chr5:	SUB1	SUB1	93.66
72	(SEQ ID NO: 72)	32591614

sgRNA_	TGGAGAAAGACGTAACTTCG	chr4:	TET2	TET2	83.53
73	(SEQ ID NO: 73)	105234315

sgRNA_	TCTGCCCTGAGGTATGCGAT	chr4:	TET2	TET2	90.97
74	(SEQ ID NO: 74)	105234747

sgRNA_	ATTCCGCTTGGTGAAAACGA	chr4:	TET2	TET2	89.62
75	(SEQ ID NO: 75)	105235656

sgRNA_	CAGGCACAATAGAAACAACG	chr3:	TIGIT	TIGIT	92.65
76	(SEQ ID NO: 76)	114295571

sgRNA_	CCATTTGTAATGCTGACTTG	chr3:	TIGIT	TIGIT	60.75
77	(SEQ ID NO: 77)	114295700

sgRNA_	CTGGGTCACTTGTGCCGTGG	chr3:	TIGIT	TIGIT	87.99
78	(SEQ ID NO: 78)	114295634

sgRNA_	GTCAGGGTTCTGGATATCTG	chr14:	TRAC	TRAC	98.20
79	(SEQ ID NO: 79)	22547508

sgRNA_	TGGATTTAGAGTCTCTCAGC	chr14:	TRAC	TRAC	88.15
80	(SEQ ID NO: 80)	22547541

sgRNA_	CTGCGGCTGTGGTCCAGCTG	chr14:	TRAC	TRAC	94.77
81	(SEQ ID NO: 81)	22550661

sgRNA_	ACAAAACTGTGCTAGACATG	chr14:	TRAC	TRAC	87.86
82	(SEQ ID NO: 82)	22547658

sgRNA_	TTCTTCCCCAGCCCAGGTAA	chr14:	TRAC	TRAC	89.85
83	(SEQ ID NO: 83)	22547778

sgRNA_	CGTCATGAGCAGATTAAACC	chr14:	TRAC	TRAC	95.81
84	(SEQ ID NO: 84)	22550625

sgRNA_	GAGAGCGCCTGCGACCCGAG	chr19:	TRIM28	TRIM28	89.44
85	(SEQ ID NO: 85)	58544980

sgRNA_	CCAGCGGGTGAAGTACACCA	chr19:	TRIM28	TRIM28	94.79
86	(SEQ ID NO: 86)	58544869

sgRNA_	GGAGCGCTTTTCGCCGCCAG	chr19:	TRIM28	TRIM28	91.81
87	(SEQ ID NO: 87)	58544839

sgRNA_	TGAGGCCTGGACCTTATGCA	chr10:	chr10:	desert_	69.44
88	(SEQ ID NO: 88)	33134193	33130000-	1
			33140000	(GS88)

sgRNA_	CCTGGTGGAGTGAACCATGA	chr10:	chr10:	desert_	95.25
89	(SEQ ID NO: 89)	33132917	33130000-	1
			33140000	(GS89)

sgRNA_	CAAGCACTTAGGTTCCCCTG	chr10:	chr10:	desert_	91.13
90	(SEQ ID NO: 90)	33134633	33130000-	1
			33140000	(GS90)

sgRNA_	GGTCTCCCTACAATTCAGCG	chr10:	chr10:	desert_	92.02
91	(SEQ ID NO: 91)	72294568	72290000-	2
			72300000	(GS91)

sgRNA_	CACAGCGCGTGACTGCAATG	chr10:	chr10:	desert_	90.22
92	(SEQ ID NO: 92)	72298268	72290000-	2
			72300000	(GS92)

sgRNA_	TCTGGGGCACCAATTCTAGG	chr10:	chr10:	desert_	86.35
93	(SEQ ID NO: 93)	72292786	72290000-	2
			72300000	(GS93)

sgRNA_	GAGCCATGCTTGGCTTACGA	chr11:	chr11:	desert_	91.24
94	(SEQ ID NO: 94)	128342576	128340000-	3
			128350000	(GS94)

sgRNA_	GTACAAGTACTTATCTCATG	chr11:	chr11:	desert_	89.02
95	(SEQ ID NO: 95)	128343592	128340000-	3
			128350000	(GS95)

sgRNA_	GAGATAACAACATAACAACA	chr11:	chr11:	desert_	96.47
96	(SEQ ID NO: 96)	128347170	128340000-	3
			128350000	(GS96)

sgRNA_	CATATTCCATAGTCTTTGGG	chr11:	chr11:	desert_	88.54
97	(SEQ ID NO: 97)	65425000	65425000-	4
			65427000	(GS97)
			(NEAT1)

sgRNA_	CTGCCCCTTAGCAACTTAGG	chr11:	chr11:	desert_	92.76
98	(SEQ ID NO: 98)	65425507	65425000-	4
			65427000	(GS98)
			(NEAT1)

sgRNA_	TGTTTAAAAATATGTTGACA	chr11:	chr11:	desert_	90.76
99	(SEQ ID NO: 99)	65426264	65425000-	4
			65427000	(GS99)
			(NEAT1)

sgRNA_	CCAGGAATGGAAACTCACGC	chr15:	chr15:	desert_	87.84
100	(SEQ ID NO: 100)	92830315	92830000-	5
			92840000	(GS100)

sgRNA_	GAGGCCGCTGAATTAACCCG	chr15:	chr15:	desert_	85.32
101	(SEQ ID NO: 101)	92831850	92830000-	5
			92840000	(GS101)

sgRNA_	ATACACGCACACTTGCAGAA	chr15:	chr15:	desert_	99.92
102	(SEQ ID NO: 102)	92831131	92830000-	5
			92840000	(GS102)

sgRNA_	GAGCAGACAGAAACCCAGGG	chr16:	chr16:	desert_	87.92
103	(SEQ ID NO: 103)	11225670	11220000-	6
			11230000	(GS103)

sgRNA_	TGAGTCTCCAAACAGAACAG	chr16:	chr16:	desert_	88.53
104	(SEQ ID NO: 104)	11226284	11220000-	6
			11230000	(GS104)

sgRNA_	TAATATCACTGACTTCACGG	chr16:	chr16:	desert_	87.65
105	(SEQ ID NO: 105)	11225029	11220000-	6
			11230000	(GS105)

sgRNA_	TACACACAATGTAAGCAGCA	chr2:	chr2:	desert_	71.79
106	(SEQ ID NO: 106)	87467461	87460000-	7
			87470000	(GS106)

sgRNA_	GGGAGCTCAATTCGAAACCA	chr2:	chr2:	desert_	65.89
107	(SEQ ID NO: 107)	87468809	87460000-	7
			87470000	(GS107)

sgRNA_	TTGGACAGGTGAGACAGTCG	chr2:	chr2:	desert_	72.64
108	(SEQ ID NO: 108)	87467001	87460000-	7
			87470000	(GS108)

sgRNA_	AAGCTCACTCAGATAGTGTG	chr3:	chr3:	desert_	76.89
109	(SEQ ID NO: 109)	186511316	186510000-	8
			186520000	(GS109)

sgRNA_	CAGGAGAACCACCTTACACG	chr3:	chr3:	desert_	86.31
110	(SEQ ID NO: 110)	186515260	186510000-	8
			186520000	(GS110)

sgRNA_	GGACAGACCCTGATTCACAA	chr3:	chr3:	desert_	85.47
111	(SEQ ID NO: 111)	186519655	186510000-	8
			186520000	(GS111)

sgRNA_	ACATGGCAGTCTATGAACAG	chr3:	chr3:	desert_	87.77
112	(SEQ ID NO: 112)	59451154	59450000-	9
			59460000	(GS112)

sgRNA_	CCTATAGAGAGTACTACTTG	chr3:	chr3:	desert_	79.33
113	(SEQ ID NO: 113)	59456416	59450000-	9
			59460000	(GS113)

sgRNA_	CCAACCGGGTCTTCATTACG	chr3:	chr3:	desert_	92.21
114	(SEQ ID NO: 114)	59457029	59450000-	9
			59460000	(GS114)

sgRNA_	TCAAGCGTAGAGTTCCGAGT	chr8:	chr8:	desert_	93.07
115	(SEQ ID NO: 115)	127993006	127980000-	10
			128000000	(GS115)

sgRNA_	TCATGCAATTATGGACCCAG	chr8:	chr8:	desert_	89.40
116	(SEQ ID NO: 116)	127994663	127980000-	10
			128000000	(GS116)

sgRNA_	CGGGAAAGTGACTGGCCATG	chr8:	chr8:	desert_	87.45
117	(SEQ ID NO: 117)	127996766	127980000-	10
			128000000	(GS117)

sgRNA_	TGAGATTGAAATCAAATCGG	chr9:	chr9:	desert_	84.84
118	(SEQ ID NO: 118)	7974159	7970000-	11
			7980000	(GS118)

sgRNA_	TATGCAATATTCATCACGCG	chr9:	chr9:	desert_	85.44
119	(SEQ ID NO: 119)	7977914	7970000-	11
			7980000	(GS119)

sgRNA_	AATGTGTTAAATCAAATGCA	chr9:	chr9:	desert_	83.48
120	(SEQ ID NO: 120)	7976895	7970000-	11
			7980000	(GS120)

TABLE 5

CONSTRUCTS USED FOR EVALUATION OF PREDICTED LOCI

Construct name	Sequence	Length

pARBI-903:	ATCTCGGCCAATAAAGGAGAAAGGGCGCGGCCCGTACGCGCGCCAGGTGC	1806
APRT_1_	GTGGGCGAGACCAGCTCACGCCCCTCCTCCAGCCGCCAAGGCCCCGGCCC
Endogenous_1	ACAGCTGCCTGGCTGCAGTCAGAAGCGTAGCCCGAGACAAGGAAGGGCGC
	CTTGACTCGCACTTTTGTCCGGTTCGAACGTTCTGctcagtggtgcgtgg
	aatgcgagcgcgtcttaaaatcgatggcgcctaggagtccatgaaatacg
	gTACAGGCTTCCGGCGACGGATGCCCCGCCCCTCACCCACGCTCCGCCCT
	CCGGGGATGCCCCACCCCTCGTGGCGGTCCCGCCCGTCCCCGCGCAGGCG
	CGCTCGGGCTGCCGCTGGCTCTTCGCACGCGGCCATGGCCGACTCCGAGC
	TGCAGCTGGTTGAGCAGCGGATCCGCAGCTTCCCCGACTTCCCCACCCCA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGGCGTGGTATTCAGGTGCACGCACAGGCCGCCCTCGTGGCGCCC
	CGACCTGCGGGCCTACGGATGGGAGCGCGTGGCCCGCGACCTCCGGGCGG
	GCGGGGGGGGAACCCTCGTCTTTCGCCCCCGGGGCCCTGCCCTCCTTCGG
	CCCCGGCGTCACCAGGCCTGTCCTTGGGTCCAGGGACATCTCGCCCGTCC
	TGAAGGACCCCGCCTCCTTCCGCGCCGCCATCGGCCTCCTGGCGCGACAC
	CTGAAGGCGACCCACGGGGGCCGCATCGACTACATCGCAGGCGAGTGCCC
	AGTGGCCGCATCTAGGGCGCTTCCGCCTCTGCGCGCGCCGAGGGCAGCAC
	GTGGGCTCTGCGCGTCTGCTTGGGGGAGGGCCTTTGGGGTGCTTCAGGGG
	GCGCCGGGACGGGCGCCGTGCTTGGGTCGCCCGGGAAGGGTTGTGAGATT
	GAGCCC
	(SEQ ID NO: 123)

pARBI-904:	TGCCCCGCCCCTCACCCACGCTCCGCCCTCCGGGGATGCCCCACCCCTCG	1806
APRT_2_	TGGCGGTCCCGCCCGTCCCCGCGCAGGCGCGCTCGGGCTGCCGCTGGCTC
Endogenous_2	TTCGCACGCGGCCATGGCCGACTCCGAGCTGCAGCTGGTTGAGCAGCGGA
	TCCGCAGCTTCCCCGACTTCCCCACCCCAGGCGTGGTATTCAGGTGCACG
	CACAGGCCGCCCTCGTGGCGCCCCGACCTGCGGGCCTACGGATGGGAGCG
	CGTGGCCCGCGACCTCCGGGGGGGGGGGGCGGGAACCCTCGTCTTTCGCC
	CCCGGGGCCCTGCCCTCCTTCGGCCCCGGCGTCACCAGGCCTGTCCTTGG
	GTCCAGGGACATCTCGCCCGTCCTGAAGGACCCCGCCTCCTTCCGCGCCG
	CCATCGGCCTCCTGGCGCGACACCTGAAGGCGACCCACGGGGGCCGCATC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGACTACATCGCAGGCGAGTGCCCAGTGGCCGCATCTAGGGCGCT
	TCCGCCTCTGCGCGCGCCGAGGGCAGCACGTGGGCTCTGCGCGTCTGCTT
	GGGGGAGGGCCTTTGGGGTGCTTCAGGGGGCGCCGGGACGGGCGCCGTGC
	TTGGGTCGCCCGGGAAGGGTTGTGAGATTGAGCCCCCGAGGCCGCCGCGC
	TGTGCAGGCGTCCTTCCCGCAGGTTCCGGGTCCCCAGCCCAGGACAGGCG
	TGACCGAGTTGCCGGGTCAGTTGGTCTCCCTGGAGTGCCCAAGCTGAATC
	CACAGGGCCCAGCTGCCTTGCTTCTTGTTCCTTCTGCGAGCTGGTATTGA
	GCGCCTGCCACGAGCCAGGCCTTCCCTGGTGAAGATCACGGAATGCCCAC
	CCAGGGAAGGGAGGCCTGGAGGCCTCCGGGAGAGCCCAAGAGGTGGCCCA
	GGGAGA
	(SEQ ID NO: 124)

pARBI-905:	CGTTCTGctcagtggtgcgtggaatgcgagcgcgtcttaaaatcgatggc	1806
APRT_3_	gcctaggagtccatgaaatacggTACAGGCTTCCGGCGACGGATGCCCCG
Endogenous_3	CCCCTCACCCACGCTCCGCCCTCCGGGGATGCCCCACCCCTCGTGGCGGT
	CCCGCCCGTCCCCGCGCAGGCGCGCTCGGGCTGCCGCTGGCTCTTCGCAC
	GCGGCCATGGCCGACTCCGAGCTGCAGCTGGTTGAGCAGCGGATCCGCAG
	CTTCCCCGACTTCCCCACCCCAGGCGTGGTATTCAGGTGCACGCACAGGC
	CGCCCTCGTGGCGCCCCGACCTGCGGGCCTACGGATGGGAGCGCGTGGCC
	CGCGACCTCCGGGCGGGCGGGGGGGGAACCCTCGTCTTTCGCCCCCGGGG
	CCCTGCCCTCCTTCGGCCCCGGCGTCACCAGGCCTGTCCTTGGGTCCAGG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGACATCTCGCCCGTCCTGAAGGACCCCGCCTCCTTCCGCGCCGC
	CATCGGCCTCCTGGCGCGACACCTGAAGGCGACCCACGGGGGCCGCATCG
	ACTACATCGCAGGCGAGTGCCCAGTGGCCGCATCTAGGGCGCTTCCGCCT
	CTGCGCGCGCCGAGGGCAGCACGTGGGCTCTGCGCGTCTGCTTGGGGGAG
	GGCCTTTGGGGTGCTTCAGGGGGCGCCGGGACGGGCGCCGTGCTTGGGTC
	GCCCGGGAAGGGTTGTGAGATTGAGCCCCCGAGGCCGCCGCGCTGTGCAG
	GCGTCCTTCCCGCAGGTTCCGGGTCCCCAGCCCAGGACAGGCGTGACCGA
	GTTGCCGGGTCAGTTGGTCTCCCTGGAGTGCCCAAGCTGAATCCACAGGG
	CCCAGCTGCCTTGCTTCTTGTTCCTTCTGCGAGCTGGTATTGAGCGCCTG
	CCACGA
	(SEQ ID NO: 125)

pARBI-906:	AGTAATTTGATGGGGGCTATTATGAACTGAGAAATGAACTTTGAAAAGTA	1806
B2M_1_	TCTTGGGGCCAAATCATGTAGACTCTTGAGTGATGTGTTAAGGAATGCTA
Endogenous_4	TGAGTGCTGAGAGGGCATCAGAAGTCCTTGAGAGCCTCCAGAGAAAGGCT
	CTTAAAAATGCAGCGCAATCTCCAGTGACAGAAGATACTGCTAGAAATCT
	GCTAGAAAAAAAACAAAAAAGGCATGTATAGAGGAATTATGAGGGAAAGA
	TACCAAGTCACGGTTTATTCTTCAAAATGGAGGTGGCTTGTTGGGAAGGT
	GGAAGCTCATTTGGCCAGAGTGGAAATGGAATTGGGAGAAATCGATGACC
	AAATGTAAACACTTGGTGCCTGATATAGCTTGACACCAAGTTAGCCCCAA
	GTGAAATACCCTGGCAATATTAATGTGTCTTTTCCCGATATTCCTCAGGT
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatACTCCAAAGATTCAGGTTTACTCACGTCATCCAGCAGAGAATGG
	AAAGTCAAATTTCCTGAATTGCTATGTGTCTGGGTTTCATCCATCCGACA
	TTGAAGTTGACTTACTGAAGAATGGAGAGAGAATTGAAAAAGTGGAGCAT
	TCAGACTTGTCTTTCAGCAAGGACTGGTCTTTCTATCTCTTGTACTACAC
	TGAATTCACCCCCACTGAAAAAGATGAGTATGCCTGCCGTGTGAACCATG
	TGACTTTGTCACAGCCCAAGATAGTTAAGTGGGGTAAGTCTTACATTCTT
	TTGTAAGCTGCTGAAAGTTGTGTATGAGTAGTCATATCATAAAGCTGCTT
	TGATATAAAAAAGGTCTATGGCCATACTACCCTGAATGAGTCCCATCCCA
	TCTGATATAAACAATCTGCATATTGGGATTGTCAGGGAATGTTCTTAAAG
	ATCAGA
	(SEQ ID NO: 126)

pARBI-907:	AAGATCTTAATCTTCTGGGTTTCCGTTTTCTCGAATGAAAAATGCAGGTC	1806
B2M_2_	CGAGCAGTTAACTGGCTGGGGCACCATTAGCAAGTCACTTAGCATCTCTG
Endogenous_5	GGGCCAGTCTGCAAAGCGAGGGGGCAGCCTTAATGTGCCTCCAGCCTGAA
	GTCCTAGAATGAGCGCCCGGTGTCCCAAGCTGGGGCGCGCACCCCAGATC
	GGAGGGCGCCGATGTACAGACAGCAAACTCACCCAGTCTAGTGCATGCCT
	TCTTAAACATCACGAGACTCTAAGAAAAGGAAACTGAAAACGGGAAAGTC
	CCTCTCTCTAACCTGGCACTGCGTCGCTGGCTTGGAGACAGGTGACGGTC
	CCTGCGGGCCTTGTCCTGATTGGCTGGGCACGCGTTTAATATAAGTGGAG
	GCGTCGCGCTGGCGGGCATTCCTGAAGCTGACAGCATTCGGGCCGAGATG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTCTCGCTCCGTGGCCTTAGCTGTGCTCGCGCTACTCTCTCTTTC
	TGGCCTGGAGGCTATCCAGCGTGAGTCTCTCCTACCCTCCCGCTCTGGTC
	CTTCCTCTCCCGCTCTGCACCCTCTGTGGCCCTCGCTGTGCTCTCTCGCT
	CCGTGACTTCCCTTCTCCAAGTTCTCCTTGGTGGCCCGCCGTGGGGCTAG
	TCCAGGGCTGGATCTCGGGGAAGCGGGGGGTGGCCTGGGAGTGGGGAAGG
	GGGTGCGCACCCGGGACGCGCGCTACTTGCCCCTTTCGGCGGGGAGCAGG
	GGAGACCTTTGGCCTACGGCGACGGGAGGGTCGGGACAAAGTTTAGGGCG
	TCGATAAGCGTCAGAGCGCCGAGGTTGGGGGAGGGTTTCTCTTCCGCTCT
	TTCGCGGGGCCTCTGGCTCCCCCAGCGCAGCTGGAGTGGGGGACGGGTAG
	GCTCG
	(SEQ ID NO: 127)

pARBI-908:	AGGAATGCTATGAGTGCTGAGAGGGCATCAGAAGTCCTTGAGAGCCTCCA	1806
B2M_3_	GAGAAAGGCTCTTAAAAATGCAGCGCAATCTCCAGTGACAGAAGATACTG
Endogenous_6	CTAGAAATCTGCTAGAAAAAAAACAAAAAAGGCATGTATAGAGGAATTAT
	GAGGGAAAGATACCAAGTCACGGTTTATTCTTCAAAATGGAGGTGGCTTG
	TTGGGAAGGTGGAAGCTCATTTGGCCAGAGTGGAAATGGAATTGGGAGAA
	ATCGATGACCAAATGTAAACACTTGGTGCCTGATATAGCTTGACACCAAG
	TTAGCCCCAAGTGAAATACCCTGGCAATATTAATGTGTCTTTTCCCGATA
	TTCCTCAGGTACTCCAAAGATTCAGGTTTACTCACGTCATCCAGCAGAGA
	ATGGAAAGTCAAATTTCCTGAATTGCTATGTGTCTGGGTTTCATCCATCC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGACATTGAAGTTGACTTACTGAAGAATGGAGAGAGAATTGAAAA
	AGTGGAGCATTCAGACTTGTCTTTCAGCAAGGACTGGTCTTTCTATCTCT
	TGTACTACACTGAATTCACCCCCACTGAAAAAGATGAGTATGCCTGCCGT
	GTGAACCATGTGACTTTGTCACAGCCCAAGATAGTTAAGTGGGGTAAGTC
	TTACATTCTTTTGTAAGCTGCTGAAAGTTGTGTATGAGTAGTCATATCAT
	AAAGCTGCTTTGATATAAAAAAGGTCTATGGCCATACTACCCTGAATGAG
	TCCCATCCCATCTGATATAAACAATCTGCATATTGGGATTGTCAGGGAAT
	GTTCTTAAAGATCAGATTAGTGGCACCTGCTGAGATACTGATGCACAGCA
	TGGTTTCTGAACCAGTAGTTTCCCTGCAGTTGAGCAGGGAGCAGCAGCAG
	CACTTG
	(SEQ ID NO: 128)

pARBI-909:	GATCTCACATTCTAGCGCCCAGACATGTCGGGAACGCCTTACGCCAACTT	1806
CAPNS1_1_	GGGGTCCCCACCAAGAGAACCCCCACCAGATCTGCACCCTCCCCTTCACG
Endogenous_7	CGTGCACCCAGTCCAGGCTCCCTCAAGCCCCACGGGTGCCTTTTAGACCT
	GAGGAGGTTGCAAACCTGATCCCCCATACCTGCCCCACCCATCCGCGGAC
	AACCCGCCCTCGCAAACTCAGACCCCCACCCGGAGGCTTCAGATTCCTCC
	CAGGTCCAGCTGCCGGAAATGCGTGTTTGAAGGGAGGGTGTGGGCTCAGG
	GGCGAAGCACCCACTGGTCCCCTTTTTTCCCCCCAGCAGTGAGTCGCAGC
	CATGTTCCTGGTTAACTCGTTCTTGAAGGGCGGCGGCGGCGGCGGCGGGG
	GAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGG
	TGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAG
	TCATCAGCGCCATCAGGTAAGGCGGAGACTATCAGAGGGGGGGGCCTGGG
	AATGGGAGGAGCCTCAGTGAGGCGTGGTCTGGGAGGGGCGTGGTCTAAAA
	ATAGAATAGGATTAACCTGGAGGCTAACCTGGGTACATGAATTAGGCCGG
	GGAGGCCTGGTTTGAGAGTTCTGCTGTAAGGGGGTGGACCCCAGTGAGGC
	GGATATCAGTCATTGGGGGCGGTGCTTGATATGGGAGTAGTCTGATTGTG
	TGGGACCAGGACAATGTGGTCCTGAGGGGACTGATGTGGAGTTTTGGCGG
	GTGGGGCTTATGGGTCTGGGCTCAGCCTGCATTGGCTAACCTGGAGATGA
	ACGTT
	(SEQ ID NO: 129)

pARBI-910:	CGGGCATTTAGGAAGCGGGCCATGGAGTAGGGTCTTGGGCAGATGGCACC	1806
CAPNS1_2_	TGAGGAGGATAAGGCCTTGGGAAGCTGGGGCAGAGCCTCTATGAAGTGAG
Endogenous_8	CCCTCCAAGGGGCGGGGTCTTTTGATTCTACGTGGGATTTTTTAGGTTTA
	GGGTGGCCAAGATGACTGAAATCTGCCACTGGGTAGGTGTGCCTGGCAGG
	AGGGGAGCCTCCCAGGGGACCGGTCTCTGGGTTTCCTCGAGGGTGGGGTT
	GGCCTGAGGAAGGGAGAAGAGGGGCACGACCAGGGCAGTGTGGATTGGGA
	CAGATGAGGACAAGAACAAATGAAAGGCACAGCAACCAAGTAAGGAAGAT
	AACGGCTGGGGTCTGGAGCGTTGGGGCTGATGGTTCTGTAGTGCTGCCCG
	TTGGAGGCCCCGCCCCTGGCACTAACCCCTCCCCCTTATCTCTTCGCAGC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGAGGCGGCTGCGCAGTACAACCCGGAGCCCCCGGTAAGCCCCCT
	CTGCAACCAGACCCCCTTCTCCTGCCAAGGCCTCTTCGAGGTCCCATCCC
	TGTTCCTGTAGAGAAGCCCCACCTTCCTCCCCTTCTTGTGAAATTCCTCT
	GCCAGTTCCTCCCATGCCGTGTCTGCAGCTTCGCCATGGGTCTTAGCCAT
	GCCCCACATACGTGCACCCCATTCACTACCACCCCTCATTCTTTTCCTCA
	TCAAGCTGCCCAGCCCACTCTGACTTCCCCACCCAGGGTACCTGGGTTTG
	GGGAGCCGTCCTGGCCGGGTTCCCCTCCCCCTGCTCTGAGCTCTCCTCCC
	TTTGCAGCCCCCACGCACACATTACTCCAACATTGAGGCCAACGAGAGTG
	AGGAGGTCCGGCAGTTCCGGAGACTCTTTGCCCAGCTGGCTGGAGATGTA
	AGTAAC
	(SEQ ID NO: 130)

pARBI-911:	GCTGATGGTTCTGTAGTGCTGCCCGTTGGAGGCCCCGCCCCTGGCACTAA	1806
CAPNS1_3_	CCCCTCCCCCTTATCTCTTCGCAGCGAGGCGGCTGCGCAGTACAACCCGG
Endogenous_9	AGCCCCCGGTAAGCCCCCTCTGCAACCAGACCCCCTTCTCCTGCCAAGGC
	CTCTTCGAGGTCCCATCCCTGTTCCTGTAGAGAAGCCCCACCTTCCTCCC
	CTTCTTGTGAAATTCCTCTGCCAGTTCCTCCCATGCCGTGTCTGCAGCTT
	CGCCATGGGTCTTAGCCATGCCCCACATACGTGCACCCCATTCACTACCA
	CCCCTCATTCTTTTCCTCATCAAGCTGCCCAGCCCACTCTGACTTCCCCA
	CCCAGGGTACCTGGGTTTGGGGAGCCGTCCTGGCCGGGTTCCCCTCCCCC
	TGCTCTGAGCTCTCCTCCCTTTGCAGCCCCCACGCACACATTACTCCAAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatATTGAGGCCAACGAGAGTGAGGAGGTCCGGCAGTTCCGGAGACT
	CTTTGCCCAGCTGGCTGGAGATGTAAGTAACCTGGGGTCCCTGGCCCCGT
	CCTAACCGTTCCATCCCTTCCCTTGTGGCTGCCCTTGCACACACACCCTT
	GACCATGACAATCCCAGTGTTCCCATTCTCCATGACATTCTCAGACCCCT
	TTCAGTCACCCCTGACCTGCCCCTAACTTCCGCCCGCAGGACATGGAGGT
	CAGCGCCACAGAACTCATGAACATTCTCAATAAGGTTGTGACACGACGTA
	AGTGACCGGGGTTAAGGAATAGGGTAGATTCAGAGGCAGAGGGGTCAGAG
	AGGATTTGACCTCTGGCCTCTGACTTTCAACCTGTTACCCACAGACCCTG
	ATCTGAAGACTGATGGTTTTGGCATTGACACATGTCGCAGCATGGTGGCC
	GTGATG
	(SEQ ID NO: 131)

pARBI-912:	ggagagttatagcagatggagacaaaaaagggaactgctggggatcaaac	1806
CBLB_1_	cttgtaaagtccttctaagtgatatatgaggactttgacttttattcaaa
Endogenous_10	gttagaaggctttgaacaaaagaattatttcatttgtgttttacaatggt
	cacaagtgccgtagcgagaataggctgTGTAGAGAAGAGATTTTGTGGTT
	TTCTTTTTTGTTCTCTGTATTCTCTTCCTGAAAAATCTGTTTTCTGCCTA
	ATCATATTTCTGTAAAGAACAATAGACTTGAACGTCTGCTGTTAAGTAAC
	AAAGGTTGACCTAAACCACATAAGGTCAGATTAACTTTTAAAATATCCAA
	GATAATGTTAAGTGTATTAAATATGGTTCAGTATGTAATCAAAATATTTG
	ATATTCTCTAGATACTAATCTCttttaatttttttattttttAGCCTTGG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGGCTCTATTTTGCGGAATTGGAATTTCTTAGCTGTGACACATCC
	AGGTTACATGGCATTTCTCACATATGATGAAGTTAAAGCACGACTACAGA
	AATATAGCACCAAACCCGGAAGGTAAGACTTTTTAGCAGTAATATTATGT
	GATATATCCAAAGATGAAAAATTCTCCATGGTTTGTTCCTAAGTAAGTCA
	GCAATACCCGCTGATGGCATGCTTGGGAGGGGGCTAGAAAAGGTAAAAGA
	CCAAAATGGTGCTTCTTAACATAATGTTTTAAATTGATACATTGTGCTTA
	CTCTGAAACTTGGTATTCATAAAGTGAAAGGGGATATGGTCTCCTTTCTG
	TTTTCATGATATCCGTGTTTATGTGCAAAATTGAATGTATATATTTGAAT
	ACTTGAATACTGTGCTAAAGAACAAATAAATAGAACAGTCTTATGTTCAT
	TACTTT
	(SEQ ID NO: 132)

pARBI-913:	CATATTACTCATTTGTGCAATGAATAAAGGATTTCTATTATTATATGGAC	1806
CBLB_2_	CCATCATCTTATGACTGTTTTTAGAAAATGAGAATTAAATCTTGATTCAT
Endogenous_11	TATTAAATAACCTTGTATACACACATGAAGAGGTCATGACACATAAGACT
	TTGACCTAATACCTTTTTTCAGATATGTTTCTATAGCTATCTTGATAGCC
	TAGGACTGTTTGAGAGAAAATTAATTTAAATTTTTGTCATATTCTTAGCA
	AATGCAAAATAATTGAGTTAAACAGAACCCACTACATTTGTTCTGAAATA
	TGAACAATATTCTCAAATATTTGTCTGGTAGTACAAATACAATTATATTA
	ATTTTATTATTGAATTTTGCTGCTTCAAAGGGAGGTATTTCTTAAATGAT
	ACTTGATTCAATTATTTCCCTTTTTTTCCACCTTGCACAGAACTATCGTA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCCATGGAAAGTATTCAGACAGTGCCTTCATGAGGTCCACCAGAT
	TAGCTCTGGCCTGGAAGCAATGGCTCTAAAATCAACAATTGATTTAACTT
	GCAATGATTACATTTCAGTTTTTGAATTTGATATTTTTACCAGGCTGTTT
	CAGGTAAGTTTATACTTGCTTAGTCTATCCATTCCCTtcttctctctccc
	tgtcttttctctctgtttctctctctctctgtctctctctcacacacaca
	cacaTAAACAAACATATGGAAAATAGTGTCATTCCTATTAGTCTGTAATT
	TTATTGGTATGTTTGGTCATTGTTAAAAGTTTAGAGTGAGCCATTTGGCT
	TAAGTTTGGAGTTATCAGATGCTGTGAGCCTGGTGGCTGCTTGTTAGCTT
	TGAGAGGATCCATCCAAAAGAGCTTTGTTTTAAACTCTCTACTTAGTTTC
	TTACTT
	(SEQ ID NO: 133)

pARBI-914:	TTAAACTTTAGAGGTTCAAAATAAGGATATGATATAGAAAAGATTGAATG	1806
CBLB_3_	GTAGGAGAACAGAATAGGATTTATTTATATTATGACAAACGTGACTATCA
Endogenous_12	GTTAATAAATTGGAGATAGTAAGTTAAGATCATTATTTATATTATGGAAA
	AATGAAGAAATAGGACATGGTTCTCTAACTTTTTAATTTTTCTGTGAAAT
	AAAATATTATGACTTATTTTATTTTTATCTTTGTTTTTAGGTAAGACTGT
	GCCAAAATCCCAAACTTCAGTTGAAAAATAGCCCACCATATATACTTGAT
	ATTTTGCCTGATACATATCAGCATTTACGACTTATATTGAGTAAATATGA
	TGACAACCAGAAACTTGCCCAACTCAGTGAGAATGAGTACTTTAAAATCT
	ACATTGATAGCCTTATGAAAAAGTCAAAACGGGCAATAAGACTCTTTAAA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGAAGGCAAGGAGAGAATGTATGAAGAACAGTCACAGGACAGGTA
	AGAAGAATATTTCAGATGTTTTGGTGTAAAGGTCATTTATGTTGCTTTTT
	ACTTAATAGTTAACCTAAACGTCACCATGTAATTGTTTTGGGGTAAATGT
	GAGTCGCTTTGTATATagtcatgtggtacttaacgatggggatactttac
	aagaaatgcatttttagacaatttcattgttgtgtggacatgatagagtg
	tacttacacagagctagatggtattacctaccgcacacctaggctgtatg
	atgtagcctattgctcctaggctgcaaatctatacagtatgttactgtac
	tgaatactgtgggcagttgtaacacaatggtaagtatgtgtgtatctaaa
	tatacctaaacatagaaaaggtatggtaaaaatactgtataaaaggccgg
	gcgtgg
	(SEQ ID NO: 134)

pARBI-915:	AGATGAGAAAACCTATCCTTCCCAATTTTTTTGTGTGAGAATTAAAATGC	1806
CD2_1_	AGCAAGAAAACACACACTCATAAACACATCTGCTTTGGCAAAGGAGCACA
Endogenous_13_	TCAGAAGGGCTGGCTTGTGCGCGCTCTTGCTCTCTGTGTATGTGTATTAT
14_15	GTTTTATGTTACTGTAAAAGATGTAAAGAGAGGCACGTGGTTAAGCTCTC
	GGGGTGTGGACTCCACCAGTCTCACTTCAGTTCCTTTTGCATGAAGAGCT
	CAGAATCAAAAGAGGAAACCAACCCCTAAGATGAGCTTTCCATGTAAATT
	TGTAGCCAGCTTCCTTCTGATTTTCAATGTTTCTTCCAAAGGTAAGCATA
	AGAGTCAAAGAAGTCCCAACCCAGCTTTCCCTGAAAGTGACTCTCAGTAA
	CTCTTTTGCTTTTTATAGGTGCAGTCTCCAAAGAGATTACGAATGCCTTG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGAAACCTGGGGTGCCTTGGGTCAGGACATCAACTTGGACATTCC
	TAGTTTTCAAATGAGTGATGATATTGACGATATAAAATGGGAAAAAACTT
	CAGACAAGAAAAAGATTGCACAATTCAGAAAAGAGAAAGAGACTTTCAAG
	GAAAAAGATACATATAAGCTATTTAAAAATGGAACTCTGAAAATTAAGCA
	TCTGAAGACCGATGATCAGGATATCTACAAGGTATCAATATATGATACAA
	AAGGAAAAAATGTGTTGGAAAAAATATTTGATTTGAAGATTCAAGGTAAG
	TGTTCATTCCCTTAATTGCTTTATTTCAGTGTGGGTGCTATTTGGCAAGT
	TGGAAAATAGCATTTCTAATATTCCCCAGCGCTGACCTCTGCCTCCAGGG
	GGGCTATACAGGAAACCAGATGCATGTCTCCTGCCCCAGTGGAGACTGTG
	GTCCAA
	(SEQ ID NO: 135)

pARBI-916:	AGGATTGTTCTAGTTGATTGGTATGTGTGCACTCCTAGTTGTTAAATATT	1806
CD3E_1_	TTCACTATCACACCTGGATATACTCAACAAATATTTGTTGAGCCAAATAC
Endogenous_16	TCAACACCAGCCAAACACGTAGTATTTACTTTAGCTTAAGCGAATTATTT
	AGCCCTGACAGAAGCCCTGGAATGTGGGTCTTTAAGTTCCTATTTTTGAG
	ATGGGAAAGCTGAGGCTCACGGAAGGAGGTGACCAGCTCAAGTCTCCTAC
	CGTCCATGCCAAATTAGAATTCCAGCCTGCCTCCTGACTTCAAGTCCAAA
	GTTCTTCCCACGCACTAAAGCTAGCTCTTCAGTGTCCTTTCTTAGGAGGT
	ACTTCCTCCCGCACCACTGACCGCCCCCTCTCTATTTCACCCCCAGCCCA
	TCCGGAAAGGCCAGCGGGACCTGTATTCTGGCCTGAATCAGAGACGCATC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTGACCCTCTGGAGAACACTGCCTCCCGCTGGCCCAGGTCTCCTC
	TCCAGTCCCCCTGCGACTCCCTGTTTCCTGGGCTAGTCTTGGACCCCACG
	AGAGAGAATCGTTCCTCAGCCTCATGGTGAACTCGCGCCCTCCAGCCTGA
	TCCCCCGCTCCCTCCTCCCTGCCTTCTCTGCTGGTACCCAGTCCTAAAAT
	ATTGCTGCTTCCTCTTCCTTTGAAGCATCATCAGTAGTCACACCCTCACA
	GCTGGCCTGCCCTCTTGCCAGGATATTTATTTGTGCTATTCACTCCCTTC
	CCTTTGGATGTAACTTCTCCGTTCAGTTCCCTCCTTTTCTTGCATGTAAG
	TTGTCCCCCATCCCAAAGTATTCCATCTACTTTTCTATCGCCGTCCCCTT
	TTGCAGCCCTCTCTGGGGATGGACTGGGTAAATGTTGACAGAGGCCCTGC
	CCCGTT
	(SEQ ID NO: 136)

pARBI-917:	AATAATAAAATAATAACAATACTTAACATTTATTGAGTGCTTATTAAGTC	1806
CD3E_2_	TCAAGCACTGTCTGTACCCAACACTTATCAAGGATTCTTTTTCATGTAAT
Endogenous_17_18	CCTCTCAACAACTATATGGGTTAAGTATCATTTTATTCCCATGAGTAAAG
	GGATGAGGAAACAGAGGGTTTGTGAGTTGAAAACACATTTCACGCTTCTC
	ACAGCTAGTGAGTAATAAAGCTGGGACTCAAACCCAGGGCTGTTTGACTC
	CAGTGCCTCTACCCACGGCCACCACTCTTTGCTTGTCAATGTTGTTCTAA
	ACATATTGAAGGGGGGGCTCTGACCGTGGCAAGCGTGTGAGTAGTAAGGG
	GAGAATGGCCTTCATGCACTCCCTCCTCACCTCCAGCGCCTTGTGTTTTC
	CTTGCTTAGTGATTTCCCCTCTCCCCACCCCACCCCCCACAGTGTGTGAG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatAACTGCATGGAGATGGATGTGATGTCGGTGGCCACAATTGTCAT
	AGTGGACATCTGCATCACTGGGGGCTTGCTGCTGCTGGTTTACTACTGGA
	GCAAGAATAGAAAGGCCAAGGCCAAGCCTGTGACACGAGGAGCGGGTGCT
	GGCGGCAGGCAAAGGGGTAAGGCTGTGGAGTCCAGTCAGAGGAGATTCCT
	GCCAAGGGGGACGACCAGCCTGGGCCAGGGTGGGTGGCAAGTCCACAGCT
	AGGTCAGAACAGCTTCTCTAGAGCTTCTATGCACAGCTTCTATTACTGTG
	ATGACAAGATCTCAACAGACGGTTTCAAATCTCACATCACTCCCCTCCTT
	CCCATCCTAGAAAAGTGCAAAAAAGTTTATGAAAGTGATGGGCTTCCTCA
	CATACCTGTCAATGCCTGCAGTCATCCGATTCCGCCCCTAAGCTGTGGGA
	AGAGAG
	(SEQ ID NO: 137)

pARBI-918:	ACTGTGACCCATGAACCAGTAGGTATTGGCGTCACCTGGGATCCTGACGT	1806
CD3G_1_	TAGTCTCTGTCAATCCTTCTCTTTAGTTCATCTATTCTACCCAAAGTGAT
Endogenous_19_20	CTCATCATCTGGTATGCTGTTAGCAGTTTCTTACCTGTATAGTATCTTCC
	AAATAACATGCCCCAAAATCCCAAAGTTTTACCCCTACTAATTACAGCAA
	TGTCTCTTTTATTCTTCACCCCCTGACGCAGATATTGGCGTCACCCGAGA
	GCATGTTAGTAATGCAGAATCTCCCCTCCCCAGAACTACTAAATAGCACC
	TGAAATTTTAACAAGATCCCCATGTGATTCATGTGCACATCAAAGTTTGA
	GAAACACTACTCTAATGATCTCCTGGTATGCAGAAGCAGGGAGAATTTCA
	GAGGCAAGATCCTTAATAGAACCACGGCTTTTCTCATTTCAGGAAACCAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTTGGTTAAGGTGTATGACTATCAAGAAGATGGTTCGGTACTTCT
	GACTTGTGATGCAGAAGCCAAAAATATCACATGGTTTAAAGATGGGAAGA
	TGATCGGCTTCCTAACTGAAGATaaaaaaaaaTGGAATCTGGGAAGTAAT
	GCCAAGGACCCTCGAGGGATGTATCAGTGTAAAGGATCACAGAACAAGTC
	AAAACCACTCCAAGTGTATTACAGAAGTATGTAATCCCCTTTGGTCTGTT
	TGTTGTGAAATTAATCAGTATTTGCTGTTCTGGTGAGCTTTTTATCTGGG
	GTGAAAGTGGAAATAGATCCTCAACAGTAATATTATCGCCTGTTCTCTTA
	ATTTCAGCTTGCCTCTTTTAAAATACTGTAAGATACTTCCCTCACCCTAT
	TGAAAAACTACAGCCAGTCCTGTAAAATTTTGTTTACCTTTGGGTGGGCT
	CCATGG
	(SEQ ID NO: 138)

pARBI-919:	TTCGAGACAAGCCTGGCCAACATGATGAAACTCTGTCTCTACTAAAAATA	1806
CD3G_3_	CAAAAAAAATTAACCAGGCGTGGAGGCGCGCGCCTGTAGTCCCAGCTACT
Endogenous_21	CAGGAGGCTGAGGCAGGAGGACCACTTGAACCCAGGAGGTCGAGGTTGCA
	GTGAGCTGCGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGAAAGAC
	TCCGTCTCAAAAAAAAAAAAGAGAGAGAGAGAAAAAGAAAAAAGACAGAG
	CCTCCATCTCCTTGTCCTCTTTCCATCCTCAGGACCATGAAGTACCCACT
	CCAAATTCTCACATATAAAAAACATTCAATAAACATGCATCAAATTAATT
	AATAGAGGATGGAAAAAATGACTTATGACTGTGCTGTCCTTTCCAGCCCC
	TCAAGGATCGAGAAGATGACCAGTACAGCCACCTTCAAGGAAACCAGTTG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatAGGAGGAATTGAACTCAGGACTCAGAGTAGGTGGGTTCTTCAAT
	GCCAATTCTAATAAAGGACCCTTGCATCAACTGCCCTCGCAATTGCTTCT
	AAGTCTAGCTCCCTTCCCTAAGCGGCTATAAGCATCAGACTCTGGGGATC
	AGGGATTGGGACGTGGTTTGGGGTACTCTTTTCTAAAAATTCTGGGGCCA
	TACTGATTGTCTTGGCCTAGGTAAATATGAATTTTATGTATCTGTAAATC
	CTGTCAGAGCAGGGCCTCAAGCCATAGAGATGCTGAATATTAATCTTAAC
	CTACATTTGAATTTCTCATTATCTACACTATTAACATTTTGGGCTAATTA
	ATTATTTGTGATGAGGGGCTAGCCTGTGCATTGTAGGAGTTATGGAAGCA
	TCCCTGGCCTCTCTCCACCAGATGCTGGTAGATTGTCCAGTGTGACAATC
	AAAAAT
	(SEQ ID NO: 139)

pARBI-920:	GACCTCAGGTGATCTGCCCGCCTCAGCTTCCCAAAGTGCTGGGATTACAG	1806
CD5_1_	GCATGAGCCACCACACCTGGCCTAAAATTAATTTTTAAAGATCTCTTAAA
Endogenous_22	AAGCAGACACCAGCCCCAATCTCAGACCCCTTGAGACAGAATTTCCAGGA
	CAGGGGCCATCCTGCTGGACAGTGGGTGCCGAGAACACCTTGCCCATTTA
	TCTGAGCTCCCTTCTGACTCTGAAATCTGGAGCCCCACCCTCCTGGGTCT
	AGCTTCGGGGCTGCCTGGGTCAGGGTCCTCTGGGAAGCCCCTGCAGTGCC
	CCAGAAGGGACGAAGCTCACAAGGGGCAAGGCAGGCAGCCCACGGGGCAG
	GAGGGAGCTCAACTGGGCGTCCTAGGGAGAGGGCAGTGAGGGGTGCCAGT
	GGGGAACCCCTCCCAGCCTGACCCCCACCACACCTTTCTGACCCCCAGAT
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTTCCAGGCAAGGCTCACCCGTTCCAACTCGAAGTGCCAGGGCCA
	GCTGGAGGTCTACCTCAAGGACGGATGGCACATGGTTTGCAGCCAGAGCT
	GGGGCCGGAGCTCCAAGCAGTGGGAGGACCCCAGTCAAGCGTCAAAAGTC
	TGCCAGCGGCTGAACTGTGGGGTGCCCTTAAGCCTTGGCCCCTTCCTTGT
	CACCTACACACCTCAGAGCTCAATCATCTGCTACGGACAACTGGGCTCCT
	TCTCCAACTGCAGCCACAGCAGAAATGACATGTGTCACTCTCTGGGCCTG
	ACCTGCTTAGGTGGGTAACTAGCCAGCCACACGGGCACCCTGGGCCTGGG
	CGCCAGCCCCGAGGAGACTGCCCGAGGCCTGTGATCTAGGGTCTGAGCAG
	GCTGGTGGAAGGGGTGGGGGGACCCCAGTTTATAACCACTCCCCAAGACA
	CATACC
	(SEQ ID NO: 140)

pARBI-921:	GGACAGGGGCCATCCTGCTGGACAGTGGGTGCCGAGAACACCTTGCCCAT	1806
CD5_2_	TTATCTGAGCTCCCTTCTGACTCTGAAATCTGGAGCCCCACCCTCCTGGG
Endogenous_23	TCTAGCTTCGGGGCTGCCTGGGTCAGGGTCCTCTGGGAAGCCCCTGCAGT
	GCCCCAGAAGGGACGAAGCTCACAAGGGGCAAGGCAGGCAGCCCACGGGG
	CAGGAGGGAGCTCAACTGGGCGTCCTAGGGAGAGGGCAGTGAGGGGTGCC
	AGTGGGGAACCCCTCCCAGCCTGACCCCCACCACACCTTTCTGACCCCCA
	GATTTCCAGGCAAGGCTCACCCGTTCCAACTCGAAGTGCCAGGGCCAGCT
	GGAGGTCTACCTCAAGGACGGATGGCACATGGTTTGCAGCCAGAGCTGGG
	GCCGGAGCTCCAAGCAGTGGGAGGACCCCAGTCAAGCGTCAAAAGTCTGC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCAGCGGCTGAACTGTGGGGTGCCCTTAAGCCTTGGCCCCTTCCT
	TGTCACCTACACACCTCAGAGCTCAATCATCTGCTACGGACAACTGGGCT
	CCTTCTCCAACTGCAGCCACAGCAGAAATGACATGTGTCACTCTCTGGGC
	CTGACCTGCTTAGGTGGGTAACTAGCCAGCCACACGGGCACCCTGGGCCT
	GGGCGCCAGCCCCGAGGAGACTGCCCGAGGCCTGTGATCTAGGGTCTGAG
	CAGGCTGGTGGAAGGGGTGGGGGGACCCCAGTTTATAACCACTCCCCAAG
	ACACATACCCAGGAGGGGGACTGGAAGGGGCCAGCACCCATCTGTAGGAT
	GGCAATGGAGGACCTAGTTCTGCCAATCACTGACTTCATCGTCGCCTCTG
	AACCTCCATTCTCCCATCTGTGAAGTGGGGTGGTACTTCCCGCCTCGCAG
	GAGGCT
	(SEQ ID NO: 141)

pARBI-922:	tgctgggattacaggcatgagccaccacacctggcctaaaattaattttt	1806
CD5_3_	aaagaTCTCTTAAAAAGCAGACACCAGCCCCAATCTCAGACCCCTTGAGA
Endogenous_24	CAGAATTTCCAGGACAGGGGCCATCCTGCTGGACAGTGGGTGCCGAGAAC
	ACCTTGCCCATTTATCTGAGCTCCCTTCTGACTCTGAAATCTGGAGCCCC
	ACCCTCCTGGGTCTAGCTTCGGGGCTGCCTGGGTCAGGGTCCTCTGGGAA
	GCCCCTGCAGTGCCCCAGAAGGGACGAAGCTCACAAGGGGCAAGGCAGGC
	AGCCCACGGGGCAGGAGGGAGCTCAACTGGGCGTCCTAGGGAGAGGGCAG
	TGAGGGGTGCCAGTGGGGAACCCCTCCCAGCCTGACCCCCACCACACCTT
	TCTGACCCCCAGATTTCCAGGCAAGGCTCACCCGTTCCAACTCGAAGTGC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCAGGGCCAGCTGGAGGTCTACCTCAAGGACGGATGGCACATGGT
	TTGCAGCCAGAGCTGGGGCCGGAGCTCCAAGCAGTGGGAGGACCCCAGTC
	AAGCGTCAAAAGTCTGCCAGCGGCTGAACTGTGGGGTGCCCTTAAGCCTT
	GGCCCCTTCCTTGTCACCTACACACCTCAGAGCTCAATCATCTGCTACGG
	ACAACTGGGCTCCTTCTCCAACTGCAGCCACAGCAGAAATGACATGTGTC
	ACTCTCTGGGCCTGACCTGCTTAGGTGGGTAACTAGCCAGCCACACGGGC
	ACCCTGGGCCTGGGCGCCAGCCCCGAGGAGACTGCCCGAGGCCTGTGATC
	TAGGGTCTGAGCAGGCTGGTGGAAGGGGTGGGGGGACCCCAGTTTATAAC
	CACTCCCCAAGACACATACCCAGGAGGGGGACTGGAAGGGGCCAGCACCC
	ATCTGT
	(SEQ ID NO: 142)

pARBI-923:	GGGGGCGGCCGCACGGCTAGAGCGGAGACCCCGCGCCCCCTCCGCCCGCG	1806
EDF1_1_	TGGCCCGGCCGGGGTGCGGGGCCCGGGGAGGCACGGGGGCTGCGCGTCGG
Endogenous_25	GGCGCAGCCGCCGCCCGCGTGTGCTCGGAGGCCGCGGGGCCCGGGCTCCG
	GGGTCCTCCCGACCTGCAGCCCCAGCGGCTACCGCGCCTCGCCAGGCCAG
	GCCAGGCCCCGACGTCGCCTTCCCTACGTCGCCGGCGCCCGGCCACGACG
	TCCCTCAGACGAGCCGAACGCCGAATGGCCCCGAGCACGGGAAGTGCCCG
	CCCCCCGCGTGCAGCCAGCCAATGGGACGCCGAAAGCGGGGAGGTGCCGA
	GGGGACGTAGCGTCGCCGCGCCAGGTCTCTAGCAGCTGCCGCTGAGCCGC
	CGGACGGACGCTCGTCTTCGCCCGCCATGGCCGAGAGCGACTGGGACACG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGTGACGGTGCTGCGCAAGAAGGGCCCTACGGCCGCCCAGGCCAA
	ATCCAAGCAGGTGCTTTGCTGACTGAGGAGCGGCCGGGCCGGGCGGGGCG
	GACGCTgggccggggccacggaccgtggggcagggggctcggggaagggc
	aggcggggcctgggacagggcgcaggggacggggacaaggctggGGTGCC
	GGGGGCAGGACGGGGTTCGAAGGGCGGGGCGAATCGCAGGGGTAGGAGGA
	CCGGGCCAGGACaggggtgggaaggtggggggcggacccaggaggggatg
	gacggacccaggaggcagggggCGGGCGACTGGAGGAGGAGAGGAGCAGG
	GAACCGGACGGGGCAAGGGGCAGGCGATAGGGCCGGGACCAGTGCCAGGG
	TGGGGCGGGGAGGGGATAGGGGCAGGGACTGTTGGTGGGGACAGGTGTGA
	GGACAG
	(SEQ ID NO: 143)

pARBI-924:	ACGGCTAGAGCGGAGACCCCGCGCCCCCTCCGCCCGCGTGGCCCGGCCGG	1806
EDF1_2_	GGTGCGGGGCCCGGGGAGGCACGGGGGCTGCGCGTCGGGGCGCAGCCGCC
Endogenous_26	GCCCGCGTGTGCTCGGAGGCCGCGGGGCCCGGGCTCCGGGGTCCTCCCGA
	CCTGCAGCCCCAGCGGCTACCGCGCCTCGCCAGGCCAGGCCAGGCCCCGA
	CGTCGCCTTCCCTACGTCGCCGGCGCCCGGCCACGACGTCCCTCAGACGA
	GCCGAACGCCGAATGGCCCCGAGCACGGGAAGTGCCCGCCCCCCGCGTGC
	AGCCAGCCAATGGGACGCCGAAAGCGGGGAGGTGCCGAGGGGACGTAGCG
	TCGCCGCGCCAGGTCTCTAGCAGCTGCCGCTGAGCCGCCGGACGGACGCT
	CGTCTTCGCCCGCCATGGCCGAGAGCGACTGGGACACGGTGACGGTGCTG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCGCAAGAAGGGCCCTACGGCCGCCCAGGCCAAATCCAAGCAGGT
	GCTTTGCTGACTGAGGAGCGGCCGGGCCGGGGGGGGCGGACGCTgggccg
	gggccacggaccgtggggcagggggctcggggaagggcaggcggggcctg
	ggacagggcgcaggggacggggacaaggctggGGTGCCGGGGGCAGGACG
	GGGTTCGAAGGGCGGGGCGAATCGCAGGGGTAGGAGGACCGGGCCAGGAC
	aggggtgggaaggtggggggcggacccaggaggggatggacggacccagg
	aggcagggggCGGGCGACTGGAGGAGGAGAGGAGCAGGGAACCGGACGGG
	GCAAGGGGCAGGCGATAGGGCCGGGACCAGTGCCAGGGTGGGGCGGGGAG
	GGGATAGGGGCAGGGACTGTTGGTGGGGACAGGTGTGAGGACAGAGGCAG
	GAGGTG
	(SEQ ID NO: 144)

pARBI-925:	CCCTGGAGTCGGTGTGAGGCAAAAGCAGAGGAGAGGATTTGGAATTAACC	1806
EDF1_3_	TGAAGAAAAACCATTTCAAAGCGGTAACCAGACCCCAGAGGCTGCCTGAA
Endogenous_27	CTCAAGGGGACATGGGAACCCAGGCTGTCCCAAGTTCACACACCTCAGGT
	CGTGGACTTCCAGAGTTTTCTCTCAGTTATGAGGACAGGCAGCTGTACTC
	ATGCCAACCAGAGCTGCTCTGGGAAGATGGCTGCCTCCCAGGGCTCCGGC
	CAGCACCGGTGCAGGCAGGCACTCAGCTGACAACGTCCCCGGGGGCGCCG
	CACACACCACACCCACCAGCACATGGACCCCACAGCACAGCCTCATGTTG
	CAAGCGGAAACACAAGTACCTACATTTCTTGGAAGTCTCCACATCTTCTC
	CTCGTCTCTGTGCCGCTAAGATAGCCTAGAAAATTAGAAAACATCAGTGG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTTTCTAAAGAGAAGATGTGCTTTATACACATCAGCTCCACTAGG
	ACTGCTGCAAAACCAGGCGCGAAGCGTCGCCTGAGAACAGCAGCTTCTAG
	GGCCCCTGGGGTACGCACCCACACGCAGCTGGGTTTTGTGCGAGAGGCAG
	TGAGAGCCGGGCTGACCTGGCTTCCCGAGGCATTCCCTGCAGGGGAACCA
	GGGGGGTGGAGCCCACCCTCCCCGTGCTATCTGAACACCGGCCATCCCCC
	TCCCCAAACCCACAACCCCAGGAGTGAGAGCCCCGGCGCAGCCTCACCGT
	GGCCAGGTCCTTCTGCGTAAGCCCCTTGCTCTGCCGACCTTGCTGGATCA
	CCTTGCCCACCTCCAGGGTCACCCTGTCATGGTGCAGCTCCTCTGTCTCC
	CGGTCCAGCTTGGCCGTGTTCTTGGTAATAGAATGTTGTTTGTTCTGGCC
	AGCAGC
	(SEQ ID NO: 145)

pARBI-926:	CTCTTGCTTCAACAGTGTTTGGACGGAACAGATCCGGGGACTCTCTTCCA	1806
FTL_1_	GCCTCCGACCGCCCTCCGATTTCCTCTCCGCTTGCAACCTCCGGGACCAT
Endogenous_2830	CTTCTCGGCCATCTCCTGCTTCTGGGACCTGCCAGCACCGTTTTTGTGGT
	TAGCTCCTTCTTGCCAACCAACCATGAGCTCCCAGATTCGTCAGAATTAT
	TCCACCGACGTGGAGGCAGCCGTCAACAGCCTGGTCAATTTGTACCTGCA
	GGCCTCCTACACCTACCTCTCTCTGGTGAGTCCCCAGGACGCCCCTGGCC
	CTAATTTCCTCCAGCTGCGCACCTCCGGCCCTCACTGCACGCGCCAGCCT
	TCTTTGTGCGGTCGGGTAAACAGAGGGCGGAGTCCCCTTGGCCTCGCCTC
	CCGCTAACCATTGTTGCCTCCATCTCTTCCCGTAGGGCTTCTATTTCGAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCGCGATGATGTGGCTCTGGAAGGCGTGAGCCACTTCTTCCGCGA
	ATTGGCCGAGGAGAAGCGCGAGGGCTACGAGCGTCTCCTGAAGATGCAAA
	ACCAGCGTGGCGGCCGCGCTCTCTTCCAGGACATCAAGGTAACTAGTGTG
	TGGGTAATGGACTACATCTCCCAGCAGGCCGTGCGCGCGAGGAGCCTTGA
	TTTGAGGGCGTAGGTGTCGCGTGGGCTTCTGGGAGATTGAGTTCGGTCTT
	GTGAGCCCTCTTAACCGCTGGAAATAGAGGCGCACCTCGTGCAGTGCCCA
	CAACACGCGGCAGTCCACACCGCTGCGTGGTCTTAGGGACGTATAGCTGT
	AAGAGCTAGGACAGGGTGCGGAGAGTGATAAATACAAGCTGTCACATGTC
	TTTGTGGCCTGGGCCTCTGACCCCCAACGACTCTTGGGAAATGTAGGTTT
	AGTTCT
	(SEQ ID NO: 146)

pARBI-927:	TGGGGCGGGGGGCTGAGACTCCTATGTGCTCCGGATTGGTCAGGCACGGC	1806
FTL_2_	CTTCGGCCCCGCCTCCTGCCACCGCAGATTGGCCGCTAGCCCTCCCCGAG
Endogenous_29	CGCCCTGCCTCCGAGGGCCGGCGCACCATAAAAGAAGCCGCCCTAGCCAC
	GTCCCCTCGCAGTTCGGCGGTCCCGCGGGTCTGTCTCTTGCTTCAACAGT
	GTTTGGACGGAACAGATCCGGGGACTCTCTTCCAGCCTCCGACCGCCCTC
	CGATTTCCTCTCCGCTTGCAACCTCCGGGACCATCTTCTCGGCCATCTCC
	TGCTTCTGGGACCTGCCAGCACCGTTTTTGTGGTTAGCTCCTTCTTGCCA
	ACCAACCATGAGCTCCCAGATTCGTCAGAATTATTCCACCGACGTGGAGG
	CAGCCGTCAACAGCCTGGTCAATTTGTACCTGCAGGCCTCCTACACCTAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCTCTCTCTGGTGAGTCCCCAGGACGCCCCTGGCCCTAATTTCCT
	CCAGCTGCGCACCTCCGGCCCTCACTGCACGCGCCAGCCTTCTTTGTGCG
	GTCGGGTAAACAGAGGGCGGAGTCCCCTTGGCCTCGCCTCCCGCTAACCA
	TTGTTGCCTCCATCTCTTCCCGTAGGGCTTCTATTTCGACCGCGATGATG
	TGGCTCTGGAAGGCGTGAGCCACTTCTTCCGCGAATTGGCCGAGGAGAAG
	CGCGAGGGCTACGAGCGTCTCCTGAAGATGCAAAACCAGCGTGGCGGCCG
	CGCTCTCTTCCAGGACATCAAGGTAACTAGTGTGTGGGTAATGGACTACA
	TCTCCCAGCAGGCCGTGCGCGCGAGGAGCCTTGATTTGAGGGCGTAGGTG
	TCGCGTGGGCTTCTGGGAGATTGAGTTCGGTCTTGTGAGCCCTCTTAACC
	GCTGGA
	(SEQ ID NO: 147)

pARBI-928:	CTTTGCATAGTTTATCCTATTAGTAATCTATTCTGTCTTTGGAATATGTT	1806
PTEN_1_	TTGTGATGATGAAATAAATACTATAAATAGTATTATTCCTTTTGCATTGA
Endogenous_31	GAGTCCTGACGAAATGTCCATGTGACAGTTCATTTTGGGTTTAGCTCTAC
	CTCTAATATGTGACCTATGCTACCAGTCCGTATAGCGTAAATTCCCAGAA
	TATATCCTCCTGAATAAAATGGGGGAAAATAATACCTGGCTTCCTTAATG
	ATTATATTTAAGACTTATCAAGAGACTATTTTCTATTTAACAATTAGAAA
	GTTAAGCAATACATTATTTTTCTCTGGAATCCAGTGTTTCTTTTAAATAC
	CTGTTAAGTTTGTATGCAACATTTCTAAAGTTACCTACTTGTTAATTAAA
	AATTCAAGAGTTTTTTTTTCTTATTCTGAGGTTATCTTTTTACCACAGTT
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGCACAATATCCTTTTGAAGACCATAACCCACCACAGCTAGAACT
	TATCAAACCCTTTTGTGAAGATCTTGACCAATGGCTAAGTGAAGATGACA
	ATCATGTTGCAGCAATTCACTGTAAAGCTGGAAAGGGACGAACTGGTGTA
	ATGATATGTGCATATTTATTACATCGGGGCAAATTTTTAAAGGCACAAGA
	GGCCCTAGATTTCTATGGGGAAGTAAGGACCAGAGACAAAAAGGTAAGTT
	ATTTTTTGATGTTTTTCCTTTCCTCTTCCTGGATCTGAGAATTTATTGGA
	AAACAGATTTTGGGTTTCTTTTTTTCCTTCAGTTTTATTGAGGTGTAATT
	GACAAGTAAAAATTATATATAAATACAATGTATAATATGATGTTTTGATG
	TATGTGTATATACATTGTGAAATGATTACTACAGTCAAACTACTTAACAT
	ATTCAT
	(SEQ ID NO: 148)

pARBI-929:	GCTACCAGTCCGTATAGCGTAAATTCCCAGAATATATCCTCCTGAATAAA	1806
PTEN_2_	ATGGGGGAAAATAATACCTGGCTTCCTTAATGATTATATTTAAGACTTAT
Endogenous_32	CAAGAGACTATTTTCTATTTAACAATTAGAAAGTTAAGCAATACATTATT
	TTTCTCTGGAATCCAGTGTTTCTTTTAAATACCTGTTAAGTTTGTATGCA
	ACATTTCTAAAGTTACCTACTTGTTAATTAAAAATTCAAGAGTTTTTTTT
	TCTTATTCTGAGGTTATCTTTTTACCACAGTTGCACAATATCCTTTTGAA
	GACCATAACCCACCACAGCTAGAACTTATCAAACCCTTTTGTGAAGATCT
	TGACCAATGGCTAAGTGAAGATGACAATCATGTTGCAGCAATTCACTGTA
	AAGCTGGAAAGGGACGAACTGGTGTAATGATATGTGCATATTTATTACAT
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCGGGGCAAATTTTTAAAGGCACAAGAGGCCCTAGATTTCTATGG
	GGAAGTAAGGACCAGAGACAAAAAGGTAAGTTATTTTTTGATGTTTTTCC
	TTTCCTCTTCCTGGATCTGAGAATTTATTGGAAAACAGATTTTGGGTTTC
	TTTTTTTCCTTCAGTTTTATTGAGGTGTAATTGACAAGTAAAAATTATAT
	ATAAATACAATGTATAATATGATGTTTTGATGTATGTGTATATACATTGT
	GAAATGATTACTACAGTCAAACTACTTAACATATTCATCACCTCACATAA
	TTATTATTCTCCCCCCAGGGTGAAAGCATTTAAGATCTACAAGCTACAAT
	TTTCAATTATACAATGTTATTATTAACTATAGTCACTATGCTGTCCAGTA
	GAGCTTCAGATCTTGTTCATCTTGTGTTCCTCCCTCCCCACCCTCAGTCC
	CTGGAA
	(SEQ ID NO: 149)

pARBI-930:	ATAAATAGTATTATTCCTTTTGCATTGAGAGTCCTGACGAAATGTCCATG	1806
PTEN_3_	TGACAGTTCATTTTGGGTTTAGCTCTACCTCTAATATGTGACCTATGCTA
Endogenous_33	CCAGTCCGTATAGCGTAAATTCCCAGAATATATCCTCCTGAATAAAATGG
	GGGAAAATAATACCTGGCTTCCTTAATGATTATATTTAAGACTTATCAAG
	AGACTATTTTCTATTTAACAATTAGAAAGTTAAGCAATACATTATTTTTC
	TCTGGAATCCAGTGTTTCTTTTAAATACCTGTTAAGTTTGTATGCAACAT
	TTCTAAAGTTACCTACTTGTTAATTAAAAATTCAAGAGTTTTTTTTTCTT
	ATTCTGAGGTTATCTTTTTACCACAGTTGCACAATATCCTTTTGAAGACC
	ATAACCCACCACAGCTAGAACTTATCAAACCCTTTTGTGAAGATCTTGAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCAATGGCTAAGTGAAGATGACAATCATGTTGCAGCAATTCACTG
	TAAAGCTGGAAAGGGACGAACTGGTGTAATGATATGTGCATATTTATTAC
	ATCGGGGCAAATTTTTAAAGGCACAAGAGGCCCTAGATTTCTATGGGGAA
	GTAAGGACCAGAGACAAAAAGGTAAGTTATTTTTTGATGTTTTTCCTTTC
	CTCTTCCTGGATCTGAGAATTTATTGGAAAACAGATTTTGGGTTTCTTTT
	TTTCCTTCAGTTTTATTGAGGTGTAATTGACAAGTAAAAATTATATATAA
	ATACAATGTATAATATGATGTTTTGATGTATGTGTATATACATTGTGAAA
	TGATTACTACAGTCAAACTACTTAACATATTCATCACCTCACATAATTAT
	TATTCTCCCCCCAGGGTGAAAGCATTTAAGATCTACAAGCTACAATTTTC
	AATTAT
	(SEQ ID NO: 150)

pARBI-931:	TAGTGACGGTATCAAGAGCAGCATCCCAGGTTGACTTTCTTTGGGGCAGG	1806
PTPN2_1_	ACCTTGCTTGTGTCTTAACCCTTGGTTCCTACccaagtttgtctctctag
Endogenous_34	tcctcaactctgaaagccacttgatatcttacacaattccttttttgcct
	gagaaaataaaagtcagttttgatcatttacaaccaaaaatcctaactaa
	cacaGACCTGTTTTTGAAATCAGGTAGATTGGAAGTCTTGGTTTACTTCT
	TATAAGCCCGTCCGCTGTCTGTCTTGTAACATCCCAGGAGCAGACTTAAC
	AAGGCCTTCCTGGAGCCTTGCTCTTTCTGTCTGCTTCCCTCATCTGctct
	ctctcctctctctTCACAGGGTCCACTTCCTAACACATGCTGCCATTTCT
	GGCTTATGGTTTGGCAGCAGAAGACCAAAGCAGTTGTCATGCTGAACCGC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatATTGTGGAGAAAGAATCGGTGAGTAATATTTAATATTTACAACT
	TAGTATACTGTATGTGATCATTAGCATATAAAGATTTTCATTTTGGGGCC
	AATATTCATTCCTTAGTTTTGGCCTTTAATTGCTAAAGGCTAGCGGTCAA
	AGTGTTTCTGTCCGGAAAAACTCATGTATCCTTTTCCTTTCTTAAGTATT
	TTTATAACAATTGCAGACCTTTCATCTCCAAGATAGAAATACAATGGAAT
	AAATATGGACTAGCAGTGACATATAGATCTTTGGAATCCCTAGGAATCCT
	TATTGACCTATTGTCAATAAGTCCTCTTCCAGCTTTAAGATCTTGTACTG
	TTCTACTTCAGATTTCTTACTTTATTCTACATTTCATAATTGCTGGTTTT
	TAATGATGATGAAAATTTCCTAATCCACTTCTAATTAGATGTGGCAATGA
	CATGCC
	(SEQ ID NO: 151)

pARBI-932:	CAGAATTTGAATATGATGTGGCTGACCATAGATACCTCCATTGCATTAAT	1806
PTPN2_2_	TCTGCTTCATAAAGTGTTTGATGCTTGCTTGTAGGTGTTGAATAGAGCCT
Endogenous_35	AATTAGCAGTAAGTAAACAGATCTagagcacagactttggcatctgaagg
	accttggttcaatgctgggactgccacttactagctatgggatctttggt
	ggatttttaacctttgaaagcctttcatccctcacagatataatggggaa
	gaaaatcgtttccattagtattgtgaggattaaatgattaattgatgtaa
	acaatgtgctttccatagtacttggcatatcataagtgcttcatGTTATT
	TTACGCTGGCTGGGAAGATAAGTTTTGCTGTGGAGAATTTAAGAGGGATA
	TTAAAATATATTTTTGTTATTTTAAGGAAATTCGAAATGAGTCCCATGAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTATCCTCATAGAGTGGCCAAGTTTCCAGAAAACAGAAATCGAAA
	CAGATACAGAGATGTAAGCCCATGTAAGTACTTGTGGGTTTGTGTGCATG
	TGTATTTTTTGGTTTGTTTTAGGAGGCAGGATGTAGTGAAAAGGAGGGCT
	TGGGGTCAGTGTTGATAAATACAGTAATTTTTTTCCTATTTACGTAAGAC
	ACGTTCTTTAAGAATTTAAAGGTGTAGAATAGTGGAAGGAAAAATAATTA
	CCCATAATTATTTCATCCTTCAAACATAGGCACCATTATTTTGGTGTATT
	TCCCACAACCTGTTTTTCTTATGCACAGTTTTCCTTTCTTTAAAATAATT
	GTAATTATAGATGTCTATATAATATCCATATGTATTTCCTTTTCATATCA
	TTCCATCCCCTTTGTAAGTTTTGCTTAAAATAGTTATTGGTGTAGTTTGG
	TTTTTT
	(SEQ ID NO: 152)

pARBI-933:	ACCAGTTATCGTTTTGTAGGTAGACCAATCAATTCTTAGGTACCAAGAAT	1806
PTPN_3_	CTGAATGATCCTTTTACTTTTAGGAAGGTAAGTACTTTATTCATTTAACT
Endogenous_36	ATGTTTACTCCTGGTCGATTTTTCAAGTCACAATGGCTAATGTGCTACAA
	ACAGAAGTGCTTCCTTTCCAGCACTATAGTAATAAACAAGATTGCATTTT
	ATACTCCTTACAAAAAAAGTAGAGAATAGTTTAGGATTTGTCTCAACTCT
	ATTATGATGCTAATTCATTTTTCTTATTTCTTCTGTCTTTTTATAAATAC
	CTAGAATATTAATATGAAGATAAAAACAGTAATTTTGAAATGACAGTTGT
	GGTTTATCATTCTCTATTTTCAGATGATCACAGTCGTGTTAAACTGCAAA
	ATGCTGAGAATGATTATATTAATGCCAGTTTAGTTGACATAGAAGAGGCA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCAAAGGAGTTACATCTTAACACAGGCAAGTAATACGATACCACG
	CAAATGTCTGAAAATGATGTGTTTGTGCTTGTTCTGCTTTAAATCATAGG
	TAAAAGTATATCTTGACTTCTTTTGGAAATGAAATGGTATTTCAGTTTTT
	TTCTGACGATGTAATGAATTATGGACATTATAAGGTTTTGAAGCTTTGAG
	TATTTAAGATAAAAGGCAAGTTATTTTTGATATTACACGTTCTGTGAAGG
	AAAATTCTTAGGAAATGGCTTAGGCCAGTTCTTTGGCAGATTGTGTTCCT
	TACATTATATCTGACACAGAGTGCTGCTTATGCTTCTTAGTGTCTTCTTT
	TCTCTTCCCATACCCTGTGGCAAAACCAGAGGCCCTGGACAGCTCTTCTG
	TAGCTCCCCCTGCCTCGCATATATCTTCAGAGAGTACACCAAGCCCTGGA
	TGGTGT
	(SEQ ID NO: 153)

pARBI-934:	CCTGCTCAAGGGCCGAGGTGTCCACGGTAGCTTCCTGGCTCGGCCCAGTC	1806
PTPN6_1_	GCAAGAACCAGGGTGACTTCTCGCTCTCCGTCAGGTAGGTGGGCCCCCCG
Endogenous_37	CAACCCCGGGCATTTTGGCCACTCTCTTGTGCCATCCAGGCCCTGAACCA
	CTCATTCCTGGTTCCCCGTGGCAGTGCTGACTCCCCGTCTGTTCCCTTGC
	CCCCAACCCCCACACTCCCCATCCCTGTCTGTGCCCACCCATGCCCATGT
	GTGCCCCCACCCAGGACCTCAGCCGATCCCTGCCCTCCTGCCTCTACTCC
	TGCACCGACTGGCCTCACCGCCTGGTGCCCTGCAGGGTGGGGGATCAGGT
	GACCCATATTCGGATCCAGAACTCAGGGGATTTCTATGACCTGTATGGAG
	GGGAGAAGTTTGCGACTCTGACAGAGCTGGTGGAGTACTACACTCAGCAG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCAGGGTGTCCTGCAGGACCGCGACGGCACCATCATCCACCTCAA
	GTACCCGCTGAACTGCTCCGATCCCACTAGTGAGAGGTGAGGGCTCCGCA
	CCCCCGCCATTCCCAAGCAGGGATGAGCCGGCTCCCACCCTGAACAGCCA
	GGGAGGCAGGGAGACTGGCAGCCGGCGCTGCCTACCCTCCATCCCCTCCC
	CTCCCTGCACCAGCTGGGGCTCTCAATGTCCCTCCTCCCTGCTGTCCTGG
	GACCTGGTGTCTCAGAGCCTAACCTACCACCCTTTCCACCTAACCCCGAG
	GAAGCCACAGAAAGCTGCCTCGCCCTACTCCGGGAGCCCTGGCCGCTGCA
	ACCCAGGTCCCACTGGAGACAGGGAGGCCACTGCTGGTGGCCAGCATGTC
	GTGCAGGCCAGCTCTGTTGTTAGAAAGCTCTTCTTCCTCTGGAATCGAGC
	CTGCCT
	(SEQ ID NO: 154)

pARBI-935:	CTGGGTTCGAAGCCCGGTTAGAACTCTGGAGGCTAGGATGGCTTGAACCT	1806
PTPN6_2_	GGGAGGTCGAGGCTGCAGAGAGCTGTAACCGCGCCACTGCACTCCAGCCT
Endogenous_38	GGGCAACAGAGCTCTGGAAGCTTGCCCTAGAGTCAGTCAAGGGCCCTAGG
	CCAGTGAGTAACAGCTCAGCGTCAGTTTCCTCATCTATAAAATGGGGGTA
	ATATCATACCTAGCTCTCAGCATGTTTGTGAGAGACCTAAATGAGGTGGT
	GGATTTGGAAGCATGTAGCGCAGTGCCTGGCACACAGTAGGTGCTTGATT
	TCCGGCCCCTCTCTGTGAATGTCTCTGCTCAGCGCCTTCCCCTGTGGCCT
	GGGTCTTACCTTCCCTGACGCTGCCTTCTCTAGGTGGTACCATGGCCACA
	TGTCTGGCGGGCAGGCAGAGACGCTGCTGCAGGCCAAGGGCGAGCCCTGG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatACGTTTCTTGTGCGTGAGAGCCTCAGCCAGCCTGGAGACTTCGT
	GCTTTCTGTGCTCAGTGACCAGCCCAAGGCTGGCCCAGGCTCCCCGCTCA
	GGGTCACCCACATCAAGGTCATGTGCGAGGTAAGGCAGCCAGGCGGCGGG
	GGAGCCTCTGCTGAGGCTCCTGTCTGTGACCACAGTGTGGGTGGCAGGGA
	GGGTCTGCCTGGGCTTGAATTCAAGGCTGGGGACCCAGGGAGGGAGACTC
	AAGTCCTGTGAATGGCCTAATTTGGCTCCCCCCAGGGTGGACGCTACACA
	GTGGGTGGTTTGGAGACCTTCGACAGCCTCACGGACCTGGTGGAGCATTT
	CAAGAAGACGGGGATTGAGGAGGCCTCAGGCGCCTTTGTCTACCTGCGGC
	AGGTCAGGGGTGGGCCCAGCTGCCTCCCCACTTCCCCTGAGCTGTCCCCC
	AGATGT
	(SEQ ID NO: 155)

pARBI-936:	TGTCACATATGTGCAATGCCATGCTCCTGAGCCTTTGATTGCAGACGTGT	1806
PTPN6_3_	GGGAAGTGGGCCCCGTCCCCACCCCCAGTGCCACCCTGCTCTGCTTCTCT
Endogenous_39	TCCCTTGCTGTGCTCTAAAACGAGAAGTACAAGTGAGTTCCCCCAAGGGG
	TCGGCCGCGCCTCTTCCTGTCCCCGCCCTGCCGGCTGCCCCAGGCCAGTG
	GAGTGGCAGCCCCAGAACTGGGACCACCGGGGGTGGTGAGGCGGCCCGGC
	ACTGGGAGCTGCATCTGAGGCTTAGTCCCTGAGCTCTCTGCCTGCCCAGA
	CTAGCTGCACCTCCTCATTCCCTGCGCCCCCTTCCTCTCCGGAAGCCCCC
	AGGATGGTGAGGTAAGGGCCTGCCACCCACGGTAGACAGGAGGCAAGGGT
	GCCTGGTGCCCACGGGACCCCTCCTCACTGCCCTGCCTGGGCCGCCCAGG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTGGTTTCACCGAGACCTCAGTGGGCTGGATGCAGAGACCCTGCT
	CAAGGGCCGAGGTGTCCACGGTAGCTTCCTGGCTCGGCCCAGTCGCAAGA
	ACCAGGGTGACTTCTCGCTCTCCGTCAGGTAGGTGGGCCCCCCGCAACCC
	CGGGCATTTTGGCCACTCTCTTGTGCCATCCAGGCCCTGAACCACTCATT
	CCTGGTTCCCCGTGGCAGTGCTGACTCCCCGTCTGTTCCCTTGCCCCCAA
	CCCCCACACTCCCCATCCCTGTCTGTGCCCACCCATGCCCATGTGTGCCC
	CCACCCAGGACCTCAGCCGATCCCTGCCCTCCTGCCTCTACTCCTGCACC
	GACTGGCCTCACCGCCTGGTGCCCTGCAGGGTGGGGGATCAGGTGACCCA
	TATTCGGATCCAGAACTCAGGGGATTTCTATGACCTGTATGGAGGGGAGA
	AGTTTG
	(SEQ ID NO: 156)

pARBI-937:	TCTTTAGCTAATGTTCTGTAGCTTGTTTTAGATCTGTGTCTACATATTAT	1806
PTPRC_1_	ATGTATCTCTGTATGCATCAATATTTGTATATATGCATGCATATATGTGT
Endogenous_40	ATGTATATTTATGAATACATATACACACCATATACATACACTTATGTATG
	GTGTGTGCATATGTATGTGTAGATATATGTACATACACACTATAGTGGAC
	TGGGGAGTTAGTATACTGGGAGGAGCATACATTTAGGGTATGATTCACAT
	ATTTATTTTGTCCTTCTCCCATTTTCCATTAATTAACAGGATTGACTACA
	GCAAAGATGCCCAGTGTTCCACTTTCAAGTGACCCCTTACCTACTCACAC
	CACTGCATTCTCACCCGCAAGCACCTTTGAAAGAGAAAATGACTTCTCAG
	AGACCACAACTTCTCTTAGTCCAGACAATACTTCCACCCAAGTATCCCCG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGACTCTTTGGATAATGCTAGTGCTTTTAATACCACAGGTTGGCA
	CACAAAAGTTGTTAACTTAAATATCAGGGAATGTCATTTAGAAAATTCTA
	CAGTTATCAGTACAACTTGTCTTTAAATTATTTGCACAGTTTCTAAGTAT
	GTGATTTTATTCAAGTGCAGAAATTGCAGGAAATTAGTATCTGTGAAATA
	TAGATCGACTGAAGTAATTAATGCATGTTGTTAGGGAGTGGAGAGAGAAA
	AGAAGGGAAGCAAGATCTCCAAGGACAATCAGGAGGGGAAATTTGTTCTA
	GTATCCTCTGATCTATACACACTCGCCATGATTCTCCCGCTTGGCTTCCC
	GCCACCTGGACAGATGAGAATTTCCCTAGTTCAGAGATTATCAGTTCTAC
	TCTCCTTGGAAGGTGTCTTAAATGGGAGTCTTCCCATTTCTTTGTTTCAC
	TCTAGA
	(SEQ ID NO: 157)

pARBI-938:	AGGGAATTTTTATATGTTGGTCATATTATATCCCTAGCATGTGGCATAAT	1806
PTPRC_2_	GTCTAGCACAAAATAGGTGCTCAATTAATCATCATTATCTAAATAAATAA
Endogenous_41	TGCATTTGGGAAAAAAAAGTTTCAAAAGTTTTTCAAAAGTCTTTTGCAGG
	CTTGAAATTAATCCCAATAGTGATCCTTTAGTCTGTTATGTTTCTGATTT
	AGCCTGGGGATTCAAAAAATAAATAACATAATTTTGATATATTTGGGCTT
	TGTAAACATGGTACTAAGAGAGGAAATATAGTTTCATTAGGGTAAAAGCT
	ACTGAAAATTGCCACTTGGTGAATGTTCTATCATAGACTTGAGGTACATA
	TAAAAATCTAATATATGTTTACATTAATATGAATGAAATTTGAAATTTTC
	TAAGAGATTTTTGTTTCTTCTTTGCAGGGCAAAGCCCAACACCTTCCCCC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatACTGGTAAGAATTAATATTTATATTTTTACTAATTTTATTTTCT
	TGTTGCAAAGTTTATATATTTAACTACAATTTTCTATTATTAACACTGAA
	ATTATTTTTAAGGATAAATTTTATAATCATGAGTGATTCTTGACATTCAC
	TTGTTCTTAAACTTTCTGCTTATACGTTATAGAGTTTAATAACTACCTAA
	ACATGTTATTAAATTTGTATATATATTTTGTGTATAAATAGTAACTTTTC
	CCAAACTTGACAGTAAATCACACAACAGGTTTCTACTCTCTTTTAATATT
	TTAAGACTATAAAAAAATGCATTTAAATTAGATAACAAAATTTTATAGTC
	TGAAAGCAGGTTAACAGCTGTCTATGTATGTTATAGATATGTAGATAACA
	GATTTGCATATGTCTATATTTCTTTAAGAGTATGTTGCTTTTTTCAATGG
	TATGCA
	(SEQ ID NO: 158)

pARBI-939:	CCTTTAGCACCATAAAGAAACTAAATTATTTAGATGTTTTTATGAGAACA	1806
PTPRC_3_	TATCAAAAAGTACTTTTCTGTCATCCAATACTTCCACAAATAAATCATTA
Endogenous_42	GTTCTTGCTAATCTTCATCTGGCATAAAAATAATGACATCAACTTTCTTC
	ATGTAATTTCCCACTTAATTCCTTTACTAGGAGCAATATCAATTCCTATA
	TGACGTCATTGCCAGCACCTACCCTGCTCAGAATGGACAAGTAAAGAAAA
	ACAACCATCAAGAAGATAAAATTGAATTTGATAATGAAGTGGACAAAGTA
	AAGCAGGATGCTAATTGTGTTAATCCACTTGGTGCCCCAGAAAAGCTCCC
	TGAAGCAAAGGAACAGGCTGAAGGTTCTGAACCCACGAGTGGCACTGAGG
	GGCCAGAACATTCTGTCAATGGTCCTGCAAGTCCAGCTTTAAATCAAGGT
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTCATAGGAAAAGACATAAATGAGGAAACTCCAAACCTCCTGTTA
	GCTGTTATTTCTATTTTTGTAGAAGTAGGAAGTGAAAATAGGTATACAGT
	GGATTAATTAAATGCAGCGAACCAATATTTGTAGAAGGGTTATATTTTAC
	TACTGTGGAAAAATATTTAAGATAGTTTTGCCAGAACAGTTTGTACAGAC
	GTATGCTTATTTTAAAATTTTATCTCTTATTCAGTAAAAAACAACTTCTT
	TGTAATCGTTATGTGTGTATATGTATGTGTGTATGGGTGTGTGTTTGTGT
	GAGAGACAGAGAAAGAGAGAGAATTCTTTCAAGTGAATCTAAAAGCTTTT
	GCTTTTCCTTTGTTTTTATGAAGAAAAAATACATTTTATATTAGAAGTGT
	TAACTTAGCTTGAAGGATCTGTTTTTAAAAATCATAAACTGTGTGCAGAC
	TCAATA
	(SEQ ID NO: 159)

pARBI-940:	aaggaaaaaggcactgagtgctggggggtgctggggtgggctgcagtgat	1806
PTPRCAP_1_	agacatcagggtagaggttaaggtcaggttcagcctcactggggtgaagt
Endogenous_43	ttgagcacggtgagcaggccatgcagcccgggggaggggaggatgggagg
	aggtggagctttccgggcagagggaacagccagtgcgaaggccccaggca
	ggtggcttaatgcagctgttgggggaggtgagtggtagggaggaggctgg
	agggatgggggctgatctcacagggccagagcctggttgaccaaataagg
	ccttggccttttctGCTTGGCTGTCCCAAGAGGATCCCAAAGAGAAAAAA
	ACGAAAGTGGTCTTGGTCACCCAGCCTGCCCCACACCAGGCCCCACCCCA
	GGTGCTGAGCCCTCTGAGCCCCTGCCTGTCTCCCACAGGCTCTGCCCTGC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatACCTTAGGGCTCGGGATGCTGCTGGCCCTGCCAGGGGCCTTGGG
	CTCGGGTGGCAGCGCGGAGGACAGCGTGGGCTCCAGCTCTGTCACCGTTG
	TCctgctgctgctgctgctcctactgctgGCCACTGGCCTAGCACTGGCC
	TGGCGCCGCCTCAGCCGTGACTCAGGGGGCTACTACCACCCGGCCCGCCT
	AGGTGCCGCGCTGTGGGGCCGCACGCGGCGCCTGCTCTGGGCCAGCCCCC
	CAGGTCGCTGGCTGCAGGCCCGAGCTGAGCTGGGGTCCACAGACAATGAC
	CTTGAGCGACAGGAGGATGAGCAGGACACAGACTATGACCACGTCGCGGA
	TGGTGGCCTGCAGGCTGACCCTGGGGAAGGCGAGCAGCAATGTGGAGAGG
	CGTCCAGCCCAGAGCAGGTCCCCGTGCGGGCTGAGGAAGCCAGAGACAGT
	GACACG
	(SEQ ID NO: 160)

pARBI-941:	aaggtcaggttcagcctcactggggtgaagtttgagcacggtgagcaggc	1806
PTPRCAP_2_	catgcagcccgggggaggggaggatgggaggaggtggagctttccgggca
Endogenous_44	gagggaacagccagtgcgaaggccccaggcaggtggcttaatgcagctgt
	tgggggaggtgagtggtagggaggaggctggagggatgggggctgatctc
	acagggccagagcctggttgaccaaataaggccttggccttttctGCTTG
	GCTGTCCCAAGAGGATCCCAAAGAGAAAAAAACGAAAGTGGTCTTGGTCA
	CCCAGCCTGCCCCACACCAGGCCCCACCCCAGGTGCTGAGCCCTCTGAGC
	CCCTGCCTGTCTCCCACAGGCTCTGCCCTGCACCTTAGGGCTCGGGATGC
	TGCTGGCCCTGCCAGGGGCCTTGGGCTCGGGTGGCAGCGCGGAGGACAGC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGTGGGCTCCAGCTCTGTCACCGTTGTCctgctgctgctgctgct
	cctactgctgGCCACTGGCCTAGCACTGGCCTGGCGCCGCCTCAGCCGTG
	ACTCAGGGGGCTACTACCACCCGGCCCGCCTAGGTGCCGCGCTGTGGGGC
	CGCACGCGGCGCCTGCTCTGGGCCAGCCCCCCAGGTCGCTGGCTGCAGGC
	CCGAGCTGAGCTGGGGTCCACAGACAATGACCTTGAGCGACAGGAGGATG
	AGCAGGACACAGACTATGACCACGTCGCGGATGGTGGCCTGCAGGCTGAC
	CCTGGGGAAGGCGAGCAGCAATGTGGAGAGGCGTCCAGCCCAGAGCAGGT
	CCCCGTGCGGGCTGAGGAAGCCAGAGACAGTGACACGGAGGGCGACCTGG
	TCCTCGGCTCCCCAGGACCAGCGAGCGCAGGGGGCAGTGCTGAGGCCCTG
	CTGAGT
	(SEQ ID NO: 161)

pARBI-942:	cagtgcgaaggccccaggcaggtggcttaatgcagctgttgggggaggtg	1806
PTPRCAP_3_	agtggtagggaggaggctggagggatgggggctgatctcacagggccaga
Endogenous 45	gcctggttgaccaaataaggccttggccttttctGCTTGGCTGTCCCAAG
	AGGATCCCAAAGAGAAAAAAACGAAAGTGGTCTTGGTCACCCAGCCTGCC
	CCACACCAGGCCCCACCCCAGGTGCTGAGCCCTCTGAGCCCCTGCCTGTC
	TCCCACAGGCTCTGCCCTGCACCTTAGGGCTCGGGATGCTGCTGGCCCTG
	CCAGGGGCCTTGGGCTCGGGTGGCAGCGCGGAGGACAGCGTGGGCTCCAG
	CTCTGTCACCGTTGTCctgctgctgctgctgctcctactgctgGCCACTG
	GCCTAGCACTGGCCTGGCGCCGCCTCAGCCGTGACTCAGGGGGCTACTAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCACCCGGCCCGCCTAGGTGCCGCGCTGTGGGGCCGCACGCGGCG
	CCTGCTCTGGGCCAGCCCCCCAGGTCGCTGGCTGCAGGCCCGAGCTGAGC
	TGGGGTCCACAGACAATGACCTTGAGCGACAGGAGGATGAGCAGGACACA
	GACTATGACCACGTCGCGGATGGTGGCCTGCAGGCTGACCCTGGGGAAGG
	CGAGCAGCAATGTGGAGAGGCGTCCAGCCCAGAGCAGGTCCCCGTGCGGG
	CTGAGGAAGCCAGAGACAGTGACACGGAGGGCGACCTGGTCCTCGGCTCC
	CCAGGACCAGCGAGCGCAGGGGGCAGTGCTGAGGCCCTGCTGAGTGACCT
	GCACGCCTTTGCTGGCAGCGCAGCCTGGGATGACAGCGCCAGGGCAGCTG
	GGGGCCAGGGCCTCCATGTCACCGCACTGTAGAGGCCGGTCTTGGTGTCC
	CATCCC
	(SEQ ID NO: 162)

pARBI-943:	ATAGAGTAGGGCGGGGGATGCCATGGAGAGGCTCCATGGGGGAGGGCCGG	1806
RPS23_1_	GGAAGCGCCGCTCCAGGAGGCACGTGGTCCGGCGCGGAAGGGGCCCATGA
Endogenous_46	GGCGTGGAGGCCGCCGAGGTCGGGGTACCGAGGGACGCAGGGAGGCCAGC
	GCTTCCTCCCGGGCATTCGAGCGGGGCCTCGTCCTTCGGGAGAACACATT
	CTCCGGAGCCCTCTTCGAACGTTTATTAGTCGGTTCAGGGCAACTTGAAG
	GCCAAATGTTTGGCCCACAGGCCAATAAATAGTACGAGAGCCAATCGGCT
	TAAGGGTTTATTCCAGGTGAGGCGAGTGTCTTAGAAGATGGGAAACACGT
	AGATGGCGTGTTTTTACGGAAGAACTAAAATATTTAATTTTTAGGCAAGT
	GTCGTGGACTTCGTACTGCTAGGAAGCTCCGTAGTCACCGACGAGACCAG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatAAGTGGCATGATAAACAGTATAAGAAAGCTCATTTGGGCACAGC
	CCTAAAGGCCAACCCTTTTGGAGGTGCTTCTCATGCAAAAGGAATCGTGC
	TGGAAAAAGTGTAAGTCCATTGCTCCCGTCAAGTTTTAGTTTATTATAGG
	AATTCGAGACATGAACTTACGAATTCTTGTTTTGAAAGTAATTGCAGGTT
	TTTGTGTAGTAGTATTCATTTGGGCATTGTGGGGTAAAATTGCAAAGCGT
	TTGTTCTATTTAAAAGTTGGTAAAATTAGTTTTTGGGAATTAGGTAGTTA
	AGGTTTTAATTTAACGTTGGCCTGGAAGGAATTGGAGAAGATACTAGCAA
	TGATGAAGTAAAGGACACAAACACCTTTACTGTGGGAGTTGTTATAAGTA
	AATGGCACGTGTCAGCTATTGAACTTTATCGACTTGATAAAACTAAGGTG
	AAGAGA
	(SEQ ID NO: 163)

pARBI-944:	CAAGCGGGACTTGGGGTCTTGGGGACGGGCGGGCGGATGCGAATAGAGTA	1806
RPS23_2_	GGGCGGGGGATGCCATGGAGAGGCTCCATGGGGGAGGGCCGGGGAAGCGC
Endogenous_47_48	CGCTCCAGGAGGCACGTGGTCCGGCGCGGAAGGGGCCCATGAGGCGTGGA
	GGCCGCCGAGGTCGGGGTACCGAGGGACGCAGGGAGGCCAGCGCTTCCTC
	CCGGGCATTCGAGCGGGGCCTCGTCCTTCGGGAGAACACATTCTCCGGAG
	CCCTCTTCGAACGTTTATTAGTCGGTTCAGGGCAACTTGAAGGCCAAATG
	TTTGGCCCACAGGCCAATAAATAGTACGAGAGCCAATCGGCTTAAGGGTT
	TATTCCAGGTGAGGCGAGTGTCTTAGAAGATGGGAAACACGTAGATGGCG
	TGTTTTTACGGAAGAACTAAAATATTTAATTTTTAGGCAAGTGCCGCGGA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCTTCGTACTGCTAGGAAGCTCCGTAGTCACCGACGAGACCAGAA
	GTGGCATGATAAACAGTATAAGAAAGCTCATTTGGGCACAGCCCTAAAGG
	CCAACCCTTTTGGAGGTGCTTCTCATGCAAAAGGAATCGTGCTGGAAAAA
	GTGTAAGTCCATTGCTCCCGTCAAGTTTTAGTTTATTATAGGAATTCGAG
	ACATGAACTTACGAATTCTTGTTTTGAAAGTAATTGCAGGTTTTTGTGTA
	GTAGTATTCATTTGGGCATTGTGGGGTAAAATTGCAAAGCGTTTGTTCTA
	TTTAAAAGTTGGTAAAATTAGTTTTTGGGAATTAGGTAGTTAAGGTTTTA
	ATTTAACGTTGGCCTGGAAGGAATTGGAGAAGATACTAGCAATGATGAAG
	TAAAGGACACAAACACCTTTACTGTGGGAGTTGTTATAAGTAAATGGCAC
	GTGTCA
	(SEQ ID NO: 164)

pARBI-945:	TTGTATATCCTTTTTAAAGTTATTCTTTTTAGTTAATTGCTCTATGTGTA
1806RTRAF_1_	TTGAGACTAGGAATCAGAAAGCTTAGATTCTAGTCCCAGGTGTAAGTTGT
Endogenous_49	GTAACCCTTGGCAAGTGTCAATCTCTAGGCCTCAGCTTTCTCATCTATAA
	AATGAGGAAGTTGTCGTATTCTATTTTTTTTCTTAAGATGATACACTTAA
	ATGTTCCCTTCTGTTGGGTTATATAATTGCATCAAAAGTGTAGTAATGTT
	ATTAAAAAATTGTTAGAGATCCAAACTAAGGTCTCTTTCAACTCTCCCAT
	TCTTTTTTCTGTGACTTTATGGTAATAATGAAACTGGTGGTTTTCTTTTC
	TTCCCCCTCACAGTATCTCAGAGATGTTAACTGTCCTTTCAAGATTCAAG
	ATCGACAAGAAGCTATTGACTGGCTTCTTGGTTTAGCTGTTAGACTTGAA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTATGGAGATAATGGTACGTTTTGTGGGGAATGTGTATTTTAAAG
	AGAGAGGAAAGATGGGAAAGGGAGTGTGAAAATGTAGGGAACTTTGCAGT
	TTGTTTTGTCTAGTACTATTTTACCTTTGGTTTATTCTTATCACAAGTTA
	AAAGCACTTTTATTGTCTTTCATTGGTGTTTATATATTTCTGTTAGAATT
	TGGAAATGGTGCCCTCTGGAGAAGGCTAATTGACTGTCTTCTCACAGAGT
	AACACTACTTTGATAATATGGTCTGCACCTTAGCCTTTCAAATTAAATTG
	TTTTTAGTGTCCCAGAATTGATGGGACTTTGAAGTGTTGTTGCAGTAGGT
	AATTTCTCAAAAGACTGAAACATGTCTAATGCCAATATACATTAATACTC
	TATAGGCCAGAATATATTACTTATGTTTACTGTCTTAGCACAGATACTTC
	TATGGT
	(SEQ ID NO: 165)

pARBI-946:	GCACCTGTTATGTAGGAGGAGTAATAAAATGAATGAATGCACTCAAAACA	1806
RTRAF_2_	CTAAACAGTAATTCTGTAATCCAACGGGAGGTACAGCGAATACCAAAAGC
Endogenous_50	CTACATATACTATTCTCTGCATGCTATAGCAAGAAAGAAAGGAAAGTGGC
	TTCCCGGTGGTTTTCTGCCTATTGTACAACCAGGAAGCTGACAATAAAGT
	TTATTTGAGCGTCGACGTGCGCCGACGTGGCCCCGCCTCCCCAGCCGGAG
	CCGCGATTGGTGGGCATTTGCCGGCGGCCACCGCTTTTAAGCCACGATTG
	GCGAAGGCCGCCGTCATTTCGGAGCGACTCAGCGCCTGCCCGCCCTCTCG
	CCGCGTCGCCGGTGCCTGCGCCTCCCGCTCCACCTCGCTTCTTCTCTCCC
	GGCCGAGGCCCGGGGGACCAGAGCGAGAAGCGGGGACCATGTTCCGACGC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatAAGTTGACGGCTCTCGACTACCACAACCCCGCCGGCTTCAACTG
	CAAAGGTGAGGCGGCGGCCTCAGCCCGGCCGCGTGTCCCTGACCTGGGCG
	GAGGTCCCAGCCTCAGTGCCCGCACCCCACCTCCCCGTCGGGACCCTCGG
	CGGCCTGGTTTCCGCCGGCAGCCTCCGGGCCCCTCTCCTCTGGGTCGCCA
	CGTACCTCGGCTCTTCGCCGCCCCTTCCCGCCTTTAAAGCCCTCTCACCT
	ACTCCTGTCTCGGCATGTTACTTTCTGCACTTGCTTAACTCCAAGCATCA
	CGTAACTACCTTCTCTGTACATAAAAGGGAGAGCATTCGTCTTTCTCACT
	CACTATTCAACTCCATGGTTCCCTGGGTAATTAGGCGATACCTTGAGCAC
	CTGCTAATTATGGGCCAGCGCGGTGCTGGATTCTGAGGAAGGTGCTGAGT
	AACTTG
	(SEQ ID NO: 166)

pARBI-947:	CACTAAACAGTAATTCTGTAATCCAACGGGAGGTACAGCGAATACCAAAA	1806
RTRAF_3_	GCCTACATATACTATTCTCTGCATGCTATAGCAAGAAAGAAAGGAAAGTG
Endogenous_51	GCTTCCCGGTGGTTTTCTGCCTATTGTACAACCAGGAAGCTGACAATAAA
	GTTTATTTGAGCGTCGACGTGCGCCGACGTGGCCCCGCCTCCCCAGCCGG
	AGCCGCGATTGGTGGGCATTTGCCGGCGGCCACCGCTTTTAAGCCACGAT
	TGGCGAAGGCCGCCGTCATTTCGGAGCGACTCAGCGCCTGCCCGCCCTCT
	CGCCGCGTCGCCGGTGCCTGCGCCTCCCGCTCCACCTCGCTTCTTCTCTC
	CCGGCCGAGGCCCGGGGGACCAGAGCGAGAAGCGGGGACCATGTTCCGAC
	GCAAGTTGACGGCTCTCGACTACCACAACCCCGCCGGCTTCAACTGCAAA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGGTGAGGCGGCGGCCTCAGCCCGGCCGCGTGTCCCTGACCTGGG
	CGGAGGTCCCAGCCTCAGTGCCCGCACCCCACCTCCCCGTCGGGACCCTC
	GGCGGCCTGGTTTCCGCCGGCAGCCTCCGGGCCCCTCTCCTCTGGGTCGC
	CACGTACCTCGGCTCTTCGCCGCCCCTTCCCGCCTTTAAAGCCCTCTCAC
	CTACTCCTGTCTCGGCATGTTACTTTCTGCACTTGCTTAACTCCAAGCAT
	CACGTAACTACCTTCTCTGTACATAAAAGGGAGAGCATTCGTCTTTCTCA
	CTCACTATTCAACTCCATGGTTCCCTGGGTAATTAGGCGATACCTTGAGC
	ACCTGCTAATTATGGGCCAGCGCGGTGCTGGATTCTGAGGAAGGTGCTGA
	GTAACTTGAAGACTAGTTCACTGCCTGCCAGGAGCTAAAGGGACGAGGGG
	TGGAAG
	(SEQ ID NO: 167)

pARBI-948:	CCGGGTTAGGCATAGGCCCTCCCGGATCTTCCGCGGTGTAAGGAGAAGGC	1806
SERF2_1_	CAGCGCCCCTGTGATAGGCCCAGAGCCCCCACTCCACAAGCCAGCCCATC
Endogenous_52	CCCCACGGAGACCCAAACCGTCCACACACACCTTGCCAGCTGTTTGGGCC
	CCACGCCGCCCCAAAACACGCCTCCAGCTGGCCCCTTGGGACCTCCCTTC
	TCTAGTCCGTATTTTGACCTGGCCCGTGGCAGATTCGCCACTCCCCCCTA
	CCCCAAGCAGCCTGGGCCTCGATGGGCCGTTGTCGGGGCCCGGAGATTGA
	AGTGGTGTTGGATCCTGCTGCTGGCCGCGCTGGGGTAGAAGGGTCGCCGG
	TGTGTGGGCAGAGCGGCCCCCGCGTCTCACCTTTAATTTTCTTTCCTTAG
	GCGGTAACCAGCGTGAGCTCGCCCGCCAGAAGAATATGAAAAAGCAGAGC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGACTCGGTTAAGGGAAAGCGCCGAGATGACGGGCTTTCTGCTGC
	CGCCCGCAAGCAGAGGTAGCCCCAGGGAGGGGAGGGAAAGGGACGGTGGA
	GACCTGGGTTAGACCAAGGGTTATAGAAGGAAAGAGAGCTACCTCAGGGC
	TTGAATGTGGACTAGTCGTGAGGAGCAGAGTGCATTGCTTCCTCTAGGGT
	TTTATTTCCTCCCCACCCTCCAAATTGTTAGCTCACAGCCTTACAGGAAA
	GGACGGGGGCGGGCGCCTGCCCTCAGTCTGATTTCTGAGCGTCCCTGGGT
	CTGACCTTAAGGGCAAGGGCAGGGAGCTTCACATTTCAAATACAGTTGTG
	GTTACGGCAGCCCAGTACTTTTGGCCCTCCTTGCTGTTCGGTTCTCCTCC
	CTTCTCCCAACCTCCTCACTGGTGTTGCTGGGTGTGGTCCTCAATACAGA
	ATAGAG
	(SEQ ID NO: 168)

pARBI-949:	AATCGAGCCCTTTGCCCACGGCTACTTCACGGGACCACCCTCCCGGGTTA	1806
SERF2_2_	GGCATAGGCCCTCCCGGATCTTCCGCGGTGTAAGGAGAAGGCCAGCGCCC
Endogenous_	CTGTGATAGGCCCAGAGCCCCCACTCCACAAGCCAGCCCATCCCCCACGG
53_54	AGACCCAAACCGTCCACACACACCTTGCCAGCTGTTTGGGCCCCACGCCG
	CCCCAAAACACGCCTCCAGCTGGCCCCTTGGGACCTCCCTTCTCTAGTCC
	GTATTTTGACCTGGCCCGTGGCAGATTCGCCACTCCCCCCTACCCCAAGC
	AGCCTGGGCCTCGATGGGCCGTTGTCGGGGCCCGGAGATTGAAGTGGTGT
	TGGATCCTGCTGCTGGCCGCGCTGGGGTAGAAGGGTCGCCGGTGTGTGGG
	CAGAGCGGCCCCCGCGTCTCACCTTTAATTTTCTTTCCTTAGGCGGTAAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCAGCGCGAGCTTGCCCGCCAGAAGAATATGAAAAAGCAGAGCGA
	CTCGGTTAAGGGAAAGCGCCGAGATGACGGGCTTTCTGCTGCCGCCCGCA
	AGCAGAGGTAGCCCCAGGGAGGGGAGGGAAAGGGACGGTGGAGACCTGGG
	TTAGACCAAGGGTTATAGAAGGAAAGAGAGCTACCTCAGGGCTTGAATGT
	GGACTAGTCGTGAGGAGCAGAGTGCATTGCTTCCTCTAGGGTTTTATTTC
	CTCCCCACCCTCCAAATTGTTAGCTCACAGCCTTACAGGAAAGGACGGGG
	GCGGGCGCCTGCCCTCAGTCTGATTTCTGAGCGTCCCTGGGTCTGACCTT
	AAGGGCAAGGGCAGGGAGCTTCACATTTCAAATACAGTTGTGGTTACGGC
	AGCCCAGTACTTTTGGCCCTCCTTGCTGTTCGGTTCTCCTCCCTTCTCCC
	AACCTC
	(SEQ ID NO: 169)

pARBI-950:	TTCAAAAGGAATCTTTTTGTTTCAACTATTAGGATCTTTTTAAATCAAAT	1806
SLC38A1_1_	ATGTATTTTAATGGTGTACACCAGACCTGAAGAAAAAGATCACAGAAGGA
Endogenous_55	ATTTCCCCTTTGTAAGATAGAGGTAGTTAAAAATAAGCCTTATGACCTAA
	TAGGTTAATTGTAATGCTCTGGTAGCCAACTTGAAAAAGGAGAAATGATG
	GTTGCATCTCACATTTTAAAATGTTAAGAATTTGTTTTGTAATGAGGATA
	CCTTAACCCCTGAAGGCCAAAATGACTATTTGTGTGAGTTTGAGAAAGGC
	ACATAGTAACTTGGGGAACAGTCAATAGAATGACAAAATCTTGACTATTT
	TAACTTTCTGAACCCTGTCATTTCTTGTGTTCTCAAATTTGATTTTTAAA
	TAGGCTGCATGGTGTATGAAAAGCTGGGGGAACAAGTCTTTGGCACCACA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGGGAAGTTCGTAATCTTTGGAGCCACCTCTCTACAGAACACTGG
	AGGTAAAAAGAACATGCTTTTCTTTACATAACTTGAAACTAATTCTGGTG
	GATGAGCGGCCACATGAATTTTAACATAATTCAAGCAGTTATCATCCTCA
	TTGCTAAAATGGCACAGGGAAAGTAAAGCAGAGACAGCAGTCACTTATTT
	AAAGCCACAAATCCTGCTAGAGTAGCTGAAGTTGCCTTTGTGTCTTACTG
	ACAGTTGGTCTAAGAACGGGCTGATAACTTTTTATGTAGCTTGCAACATA
	AGCCTTCGTATCTTCTTTCTAAAAATGTTCTCATTTTCCTTCAGCAATGC
	TGAGCTACCTCTTCATCGTAAAAAATGAACTACCCTCTGCCATAAAGTTT
	CTAATGGGAAAGGAAGAGACATTTTCGTAAGTTATAGACCATTTTTTTAT
	GATATA
	(SEQ ID NO: 170)

pARBI-951:	TAAAGATGTCAAGCTTCAAATCATTATCATAAGGTTAAATATATTACGCA	1806
SLC38A1_2_	TGTCTTTACAGCAAGTTTATTTCTGATCGTGAAAGTAGAAGAAGTCTCAC
Endogenous_56_57	AAACAGCCATTTGGAAAAAAAGAAGTGTGATGAGTATGTAAGTATCATTA
	TAATGAAGTATGCTTATTTTTTTAATCATATAAATTGGGACAAATCTTTT
	TAATTCAAGTAGCATAGTACCAAAAGCATAACTACCTGTATTCACCAGGA
	TATTCCTCATACCTTATGTATTTTCTCTTGAAATCCATTCAAGGAAATAA
	CTAGATAACTAAGAATGGATTTTCTTGAATTTTACTTCCATATTGGTTCC
	TGAGAGTGCATTAAAGGCTTTGGCTTGATGAACTTTCTTGGGGATTATTT
	TGCTTAGTGTCAATGTTTGTTTCTTTGTTCAGATTCCAGGTACAACCTCC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTTAGGCATGTCAGTTTTTAACCTAAGCAACGCCATTATGGGCAG
	TGGGATTTTGGGACTCGCCTTTGCCCTGGCAAACACTGGAATCCTACTTT
	TTCTGTGAGTATTGACGTGCCGGTACTTTCCATTTTAAAACTGAACTTTT
	TGTATGTTTCTGTTATTACATAGAAGAAATGTGAAATATTTATAAATAGT
	TTTTTTATTAACTTGGCTAAGTTACAAGTACATACTTTGATATTTATTGC
	TTGAGTGATTTTCCAAACTGTACCTAATGCTTACAACAAAGAGGAAGGAG
	AAAATCTTTTTATTAATCAAAAATACTGAAATAAGCATTTGTGAAAAGGA
	TTAAAACATTTGAAAATAACTTTTTTTGGTATTTTTGGAGTCTACCTGTG
	ACTTTAAATCTCAGTTAAAATATTAAGAGGTGTTTAACCCCAGCCAGTCA
	CCACTT
	(SEQ ID NO: 171)

pARBI-952:	ATCATTCTTCACACTAGTTCCTTTTCTGACTCTTCAGTCACCTCCAGAAT	1806
SMAD2_1_	TAATATCCTTAGAAGCATCTCTAAAATGAGTTTGATTTACTAAACATAGA
Endogenous_58	AGTTGACAAAGTTTTTCAAGTATAACTGCATAAACTCTCTTTTTTAAAAA
	ATCAGTTTTTCCCAAGTTGTTAGCCTTTCATTGGCATTTGAGTCATTTAT
	GTGACATATTTATAAGAAACATCTGCTAGTGCTGCTGCATACTTTTATCA
	GATCCATTAAATAGTACATTTTTGTTCTTGATTCTCACTAAAACTAACTA
	AATGGCTGTCATTCTTTTCTTTATGCTTTTATTGTACTAATTTAGCCCAT
	TTGACTGCACttttttttttttttttttAAAGTTCCCTCCTTTCTTTTCC
	CCTTGCTTCCCAACAGGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCC
	TGATCTTCACAGTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATG
	CTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATCAG
	AGAGTTGAGACACCAGGTAGGAATATTGCAAGTTTTTTTCTTGGTTTTGA
	ATTAAATGCCTGAACTTCAGTATATTTAAGTACTCTTGTGACCCAGGAAA
	ATTTTAGTGTAAATTCTAATAAATTACCTTAAATTGTGCATATTATTTGG
	TGGTAATTAAAAtttttttatttttaaaaatttttAATGAGAAAACATAT
	CTGTTTCTTGGAATAGCATATGATTTGGCATGAAAGTGCATATCCAGGAA
	ATCCTGTAGATTGGCAGTCTGCTCAGCGCTATGCTGATGTGCTTCTACAT
	GTCCCT
	(SEQ ID NO: 172)

pARBI-953:	TTCTATATTAAAAATCAGTTGACATCTGTTTTTAGATAATTTTTTAAAAA	1806
SMAD2_2_	ACTGGATTATAAAATGAAGCACTTAGTAAAGCTGATGGCAGAGGTTTTAG
Endogenous_59	ATCTTTTGAATACAGGAAAGTGGTAAGGGCATTATAGGTATGATTCATTG
	AGCTAGAGGGCGTTGGTGTTCACATTTTAAAAACATAATCATGACTTATC
	TGGAGTCACATGTTCCATTTTATTGGCTTCCTTCATATAGAAAATATAGT
	AACCAGCACTACATGCCTGTGAAAAAGTGAAGCAATTGTATATTTTCTGG
	GTGAAGGAAGTATTCTGTACATTCTCCATGTTTTACATCATGGTATTTTG
	AATAACCATGCTTCCATGTTCACATCAATTTTTTGTTTTTCAATTTATGC
	ACAGCACTTGCTCTGAAATTTGGGGACTGAGTACACCAAATACGATAGAT
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCAGTGGGATACAACAGGCCTTTACAGCTTCTCTGAACAAACCAG
	GTGAATATTCTGCCCTCTGTCGAATCTTAGAGATCTTGTGGGAGGGGGGT
	ATATTTTGAAAGACCTATATGGGGTTGCTTAGTATAATTTTGCCTAGGAT
	GTTTCCTTAATGTAAAATAAGGCATAGCATTTAAAATATCTGCTTGCCAG
	TATAAAAAATATATTAAATGTTTCAGCTGATGTTTTAATCAATGCAATTC
	TAGTTTGAATCTTCTTTAAATTACTGTATCCCCTAAAGAATAATAATTTT
	GATAACTATATATTTATTTTAGCTTGAGATCAGATTATAATCTGTTGTTG
	GCCTAATTTTTAAGTAGATACATGATGAGTTTTGCTAAATTTCTTGTTAT
	CAGAATCTCATCTTTATACTAATAAATACATACTTAATGAACCCCTTATA
	TCACAA
	(SEQ ID NO: 173)

pARBI-954:	TCAATGTATTTTTGTATAGTCTTTTGAGATTAGAGTGAAGTTCTAAAAAG	1806
SMAD2_3_	TAAGAGAACCTTTTGTGAAAATATTTTAATTGACACTACTAAGAGTTTAA
Endogenous_60	AATAGTATTGGTGGTGAAAAATCGTTAAAAGTATCTGATTTTACTTGCAA
	AATTACTGTATTTTCCCACAAGAGGAGTCCTTACAACATTCTTGTTTTTA
	GAAGGGTTTGTTTCCATCATTCATTTAAATTCATAAAGATAACGTTTTCA
	TGGGTGGAGAAGTCTATTGGGAAAGTCATAATTCGAATTTCTATCTTGCT
	TTGCAGTTTGCTTTCTATGATAAGTTGAAATTATTACTTGATGTTCAAGG
	TAGTCTCTACATCATCCTTTCAATATTTCTGCTAGGTTCGATACAAGAGG
	CTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTTGCCATTCACGCCGCCAGTIGTGAAGAGACTGCTGGGATGGAA
	GAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGC
	AGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTCTGGTGAAGAAGCTA
	AAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAA
	CTGTAATACTAAATGTGTTACCATACCAAGGTAAGTTTTGTTAGATCCCA
	GGTTTGATCAAATTATGTCAAGGAATCTGAAGGAAAGTTACTGAATTTGT
	GTTCCTTTCAAGTTGCCTGTAAAAAGTGATGATTGAAATATGACTGTTTT
	TAACCTTGTATAAATTGTTTTTGCTAGCTGACTTGTTTTATAAATTATTT
	TCTTGAATAGTGAGGTTTAATCAAGCTAAATAAGATACTTAGATTTATTA
	TCTTCA
	(SEQ ID NO: 174)

pARBI-955:	GGGCTCCCGCAGCACAGCCTTTCTCCGGCCCTAGCCCAAATCGCCCAGAC	1806
SOCS1_1_	CAGGCGCGGATCCCAGCCTGGCCAGCAGGCGGCGGGCGCGGGGGGCGAGC
Endogenous_61	CGGGGCCGGACGGCTGGAGCCAGAACCGGCTGCTCTCCACGCCCCCCTCT
	CGGTGCTGCCCGGAGGCCGGACTCCGCCTCCACCGAGCCCCCACCCGCCG
	GGAAGAGCTCCGCGGAGTACAGAGCCCATTTTCTAGCTGTGTCCACTGAG
	GCTGAACGGATCCGCGCGGACTTGGTGCTCCGTGCTCGCCCCCTAGGGCC
	GGGTCCGCCGGGAGCGCCGCCCTCCGGAGTTGTCCGGCCGGCGCACACCT
	GCCCGGCCCCGCAGCGCCCCAGCTCACCTCTTTGTCTCTCCCGCAGCGCA
	CCCCCGGACGCTATGGCCCACCCCTCCGGCTGGCCCCTTCTGTAGGATGt
	ccggatccggagagggcaggggatctctccttacttgtggcgacgtggag
	gagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGT
	GGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCA
	GCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTG
	AAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGT
	GACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACA
	TGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAG
	GAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCGA
	GGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCA
	TCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAAC
	TACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCAT
	CAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAGC
	TCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTG
	CTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCC
	CAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCG
	GGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagct
	tataatggttacaaataaagcaatagcatcacaaatttcacaaataaagc
	atttttttcactgcattctagttgtggtttgtccaaactcatcaatgtat
	cttatGTAGCACACAACCAGGTGGCAGCCGACAATGCAGTCTCCACAGCA
	GCAGAGCCCCGACGGCGGCCAGAACCTTCCTCCTCTTCCTCCTCCTcgcc
	cgcggcccccgcgcgcccgcggccgtgccccgcggtcccggccccggCCC
	CCGGCGACACGCACTTCCGCACATTCCGTTCGCACGCCGATTACCGGCGC
	ATCACGCGCGCCAGCGCGCTCCTGGACGCCTGCGGATTCTACTGGGGGCC
	CCTGAGCGTGCACGGGGCGCACGAGCGGCTGCGCGCCGAGCCCGTGGGCA
	CCTTCCTGGTGCGCGACAGCCGCCAGCGGAACTGCTTTTTCGCCCTTAGC
	GTGAAGATGGCCTCGGGACCCACGAGCATCCGCGTGCACTTTCAGGCCGG
	CCGCTTTCACCTGGATGGCAGCCGCGAGAGCTTCGACTGCCTCTTCGAGC
	TGCTG
	(SEQ ID NO: 175)

pARBI-956:	GGATCCCAGCCTGGCCAGCAGGCGGCGGGCGCGGGGCGGCGAGCCGGGGC	1806
SOCS1_2_	CGGACGGCTGGAGCCAGAACCGGCTGCTCTCCACGCCCCCCTCTCGGTGC
Endogenous_62	TGCCCGGAGGCCGGACTCCGCCTCCACCGAGCCCCCACCCGCCGGGAAGA
	GCTCCGCGGAGTACAGAGCCCATTTTCTAGCTGTGTCCACTGAGGCTGAA
	CGGATCCGCGCGGACTTGGTGCTCCGTGCTCGCCCCCTAGGGCCGGGTCC
	GCCGGGAGCGCCGCCCTCCGGAGTTGTCCGGCCGGCGCACACCTGCCCGG
	CCCCGCAGCGCCCCAGCTCACCTCTTTGTCTCTCCCGCAGCGCACCCCCG
	GACGCTATGGCCCACCCCTCCGGCTGGCCCCTTCTGTAGGATGGTAGCAC
	ACAACCAGGTGGCAGCCGACAATGCAGTCTCCACAGCAGCAGAGCCCCGA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCGGCGGCCAGAACCTTCCTCCTCTTCCTCCTCCTcgcccgcggc
	ccccgcgcgcccgcggccgtgccccgcggtcccggccccggCCCCCGGCG
	ACACGCACTTCCGCACATTCCGTTCGCACGCCGATTACCGGCGCATCACG
	CGCGCCAGCGCGCTCCTGGACGCCTGCGGATTCTACTGGGGGCCCCTGAG
	CGTGCACGGGGCGCACGAGCGGCTGCGCGCCGAGCCCGTGGGCACCTTCC
	TGGTGCGCGACAGCCGCCAGCGGAACTGCTTTTTCGCCCTTAGCGTGAAG
	ATGGCCTCGGGACCCACGAGCATCCGCGTGCACTTTCAGGCCGGCCGCTT
	TCACCTGGATGGCAGCCGCGAGAGCTTCGACTGCCTCTTCGAGCTGCTGG
	AGCACTACGTGGCGGCGCCGCGCCGCATGCTGGGGGCCCCGCTGCGCCAG
	CGCCGC
	(SEQ ID NO: 176)

pARBI-957:	CGGACTCCGCCTCCACCGAGCCCCCACCCGCCGGGAAGAGCTCCGCGGAG	1806
SOCS1_3_	TACAGAGCCCATTTTCTAGCTGTGTCCACTGAGGCTGAACGGATCCGCGC
Endogenous_63	GGACTTGGTGCTCCGTGCTCGCCCCCTAGGGCCGGGTCCGCCGGGAGCGC
	CGCCCTCCGGAGTTGTCCGGCCGGCGCACACCTGCCCGGCCCCGCAGCGC
	CCCAGCTCACCTCTTTGTCTCTCCCGCAGCGCACCCCCGGACGCTATGGC
	CCACCCCTCCGGCTGGCCCCTTCTGTAGGATGGTAGCACACAACCAGGTG
	GCAGCCGACAATGCAGTCTCCACAGCAGCAGAGCCCCGACGGCGGCCAGA
	ACCTTCCTCCTCTTCCTCCTCCTcgcccgcggcccccgcgcgcccgcggc
	cgtgccccgcggtcccggccccggCCCCCGGCGACACGCACTTCCGCACA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTTCCGTTCGCACGCCGATTACCGGCGCATCACGCGCGCCAGCGC
	GCTCCTGGACGCCTGCGGATTCTACTGGGGGCCCCTGAGCGTGCACGGGG
	CGCACGAGCGGCTGCGCGCCGAGCCCGTGGGCACCTTCCTGGTGCGCGAC
	AGCCGCCAGCGGAACTGCTTTTTCGCCCTTAGCGTGAAGATGGCCTCGGG
	ACCCACGAGCATCCGCGTGCACTTTCAGGCCGGCCGCTTTCACCTGGATG
	GCAGCCGCGAGAGCTTCGACTGCCTCTTCGAGCTGCTGGAGCACTACGTG
	GCGGCGCCGCGCCGCATGCTGGGGGCCCCGCTGCGCCAGCGCCGCGTGCG
	GCCGCTGCAGGAGCTGTGCCGCCAGCGCATCGTGGCCACCGTGGGCCGCG
	AGAACCTGGCTCGCATCCCCCTCAACCCCGTCCTCCGCGACTACCTGAGC
	TCCTTC
	(SEQ ID NO: 177)

pARBI-958:	GGCAGACAAACAGTTAAAACAGAGGAGTGGGGTAAGTGATGACCTAACCC	1806
SRP14_1_	AGCCCCGCTGCTCTAGTTTTGTTAAACACCTCATCTGCTATCACGGTCTG
Endogenous_64	GCGAAACCCTGGAGAAACTATTATTTCCACGACGGAAACATGTAATATCG
	AAGCACGTTAAATTCCACTCAAAGTGGCGGCGTCTGGGATCCCTGACAAA
	GAGCCCTGGGCTGCTTGGGGCCCATTGTTACCAGAAGCAACCTAGGCGGC
	TCAGTGCTGGGGACTGAGCCAGCTACAATCCCTACTATTTTCCGGGCCCG
	AAGCCCCGAATGTGCTCAGTACAGGGTGGGGAAAGGTAGAGGAAGGCGGC
	GGTCCGCGGCAGACAGACTCCGGTGGCTCCCAGACACCGGGAACCCAGGG
	AGCATCGCCCGGCTCCCCTCCCGCTGCTTACACTTCTTCAAGGTGATATA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGACGCTGCCCGACGTCCGGCACTTCTGGAAAAGTCTGGTCAGCT
	CCGTCAGGAACTGGAAAACAACAGGCCCAGCCCCGTTAGCCAGCCCCAAA
	TCCTCGTCCTGCCGCGTCAAGGCCCTGGTCCTCCTGCAGGAGGCACAGGT
	CTCGAGTAACGCCTGAGCCGCCCCCTTCCCTCGGCCGGCCAGGCCTAGCC
	ATACCTGCTCGCTCTCCAACAACACCATCGCGGCGACGCTGGCTCGACTC
	CCTCCGCTTAAGCCCCTAGCAGTGAGAGCCGGAAGTTCGGCCTAGGCTGG
	GGGGACTTCCGCTACTAGACTTCCATTGTCTTCCACCAATCTCTTCTCTT
	CCACCAATCCCGGCCTGCGCCCTCCCCCCTCCCCGCCCGCCTAGCGCCCG
	CGCCCTGGGACGTCCGGGGGCCTGTGACCCGGAGGCGCTGGGGCTGTCCT
	GGGTC
	(SEQ ID NO: 178)

pARBI-959:	GTCTGTCTGCCGCGGACCGCCGCCTTCCTCTACCTTTCCCCACCCTGTAC	1806
SRP14_2_	TGAGCACATTCGGGGCTTCGGGCCCGGAAAATAGTAGGGATTGTAGCTGG
Endogenous_	CTCAGTCCCCAGCACTGAGCCGCCTAGGTTGCTTCTGGTAACAATGGGCC
65_66	CCAAGCAGCCCAGGGCTCTTTGTCAGGGATCCCAGACGCCGCCACTTTGA
	GTGGAATTTAACGTGCTTCGATATTACATGTTTCCGTCGTGGAAATAATA
	GTTTCTCCAGGGTTTCGCCAGACCGTGATAGCAGATGAGGTGTTTAACAA
	AACTAGAGCAGCGGGGCTGGGTTAGGTCATCACTTACCCCACTCCTCTGT
	TTTAACTGTTTGTCTGCCGCTCAGCCACGTACGCGGCCGTGTTCACCAGG
	ATGCATTTTTTCCTTCAGATGACGGTCGAACCAAACCCATTCCAAAGAAG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGGTACTGTGGAGGGCTTTGAGCCCGCAGACAACAAGTGTCTGTT
	AAGAGCTACCGATGGGAAGAAGAAGATCAGCACTGTGGTGAGCTTAATTT
	CTAAGGCTGTCTTTTGAAATGTAAAGACTTGAACTTAACAGAGGATGGGG
	CGTTTCTGAACCAGGCTTTTATTTGTTTTTCCCTTTTGCCCTGTGTGGCT
	ATTTTTGAGACCAGGACCTTCCTATACTTTAGTAGTGGAAACCTCAAGAA
	TAAAATAAGAAGGTAGAGGTCAGACAGTCGTTAGTTCTGCTAAAGCTCTT
	GTGGAAATGAAAGTAGCATATTGGTCCTTATTCGTAGTACTGTAAGGAGC
	AGCTGGCATAAATATTTGATTCCTTAGCCCCTTACTGTGCTGGGCCTTCA
	ATAAGCAGTTTCTTGGTACCAGGTGATGCTATTATTTCCTTATCTTTGTG
	GTTCAC
	(SEQ ID NO: 179)

pARBI-960:	CCCACGTCAGTGAGTGCTCACAAGTCTGTGAGGTAGGCGGCGCCACAGAG	1806
SRSF9_1_	AGAAACTGAGGCGCGGGAGCCCAAGCCACTTGTCCAGCGCCTCAGCCGAG
Endogenous_67	CGCGAACCGCGCTCGGGGATGGCATCCACACGGCCCGGCCCCAGGCTCTC
	CCTGTCAGCGCCCGAAGGCCCTTCGCACCTCCAGGGGGCGCCGGCCTGCG
	CGCACGCGCAATGGTCGCAGCCGCGTTCTCTTTAAGAGGACTCCTTTTGC
	CTCCGCCGACCCCTTCGCTTCCGCTCCGCGTTCCCACAATGCAGTGCGGC
	TGAGCGCCTCGGAGCCCGCGGGGACGCTGCGGGGGGACCCGTGCTGAggc
	ggcggcggcgacgtgggctgcggcgggcccgcggcgtcgggcggtgcgga
	tgtcgggctgggcggacgagcgcggcggcgAGGGCGACGGGCGCATCTAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGTGGGGAACCTTCCGACCGACGTGCGCGAGAAGGACTTGGAGGA
	CCTGTTCTACAAGTACGGCCGCATCCGCGAGATCGAGCTCAAGAACCGGC
	ACGGCCTCGTGCCCTTCGCCTTCGTGCGCTTCGAGGACCCCCGGTGAGGc
	ccccgcgcccctgccctctcctcctcggtgcctgaggcccccgccttccc
	tgctgtcccctcccccagggctcccctccccccggcctcccctccccccg
	cctccgcgcagacccctcaCGGCGCCCCCTCACGGGTGGAGGATGAGGCA
	GCCTCTCCTCGCAGGCCCGGGCCGTCCTTCGCGCCGTCGTCACTTCCTTT
	ATTTTTATTATTCCAATATTTTACTTAGAAACCCAAAAGCTGAGCCTTTG
	GAGGGCCCAAGCCCGCCTGCACCGGCCTCGGGGGGTCCAAATGAGCCTTG
	TCCGCC
	(SEQ ID NO: 180)

pARBI-961:	TGTGGTGTGCTTTTCGAGAAAATGCTCACGAAGATTAGAAAAACACTGAT	1806
SRSF9_2_	GGTTTATTGGCAAAATCAATAATCTGTCAGCAGTTGATTCttttttttCT
Endogenous_68	CTGAATTAGCCCTCTTATGAGTAATCTGTTTGCTCATTCATTATAATTTC
	ATACCTCTAAAACTGCGTGTGACAGCTGTAAAGGTTAATTCCAGTATCAT
	GAAACGTCTCCAAACCAAAGCAGAAGTGCTTCAGGATCCTGATTTGTGTG
	TTTTTTTCTTCACTCTAGGTTTCCCTTTTATGCTTACTACTCATGCCCCT
	CACTTGGAAAGTCACTTGGCCTCCTGAACAGCACTAACTCCAAACGtttt
	ttttgttgttgttgttttttttAGAGATGCAGAGGATGCTATTTATGGAA
	GAAATGGTTATGATTATGGCCAGTGTCGGCTTCGTGTGGAGTTCCCCAGG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatACTTATGGAGGTCGGGGTGGGTGGCCCCGTGGTGGGAGGAATGG
	GCCTCCTACAAGAAGATCTGATTTCCGAGTTCTTGTTTCAGGTATGTTCC
	TTTCAAACAGaatgagatgatacatgtaaaatacttaacacagagtctgt
	cttccaagaaatgatagctgttattcttCAGTGCATGGGACACGGGGGCT
	TTCTTTTCAATAGCCTGTGTGAAGCCTTGCCCTGGATTGCCAATGAGGAA
	AGTATCCTGCAAATGAAATTGCGCTGGGAGTGCAGCCTTGGAAGAACATA
	ACCATATTTCTTGTAAAGGAGTTTTCTAGTGGTGAGAAGGAAAGATGATG
	GGAAAACTTGAGCTACAATTCTAAAGATGCTTCTTTTGGAATATACTTGG
	CATCAGACATGGTAGAAAGGCATTCAAGGAGCCAGATTTGAACAACTTAC
	CCAGCC
	(SEQ ID NO: 181)

pARBI-962:	GATGGCATCCACACGGCCCGGCCCCAGGCTCTCCCTGTCAGCGCCCGAAG	1806
SRSF9_3_	GCCCTTCGCACCTCCAGGGGGCGCCGGCCTGCGCGCACGCGCAATGGTCG
Endogenous_69	CAGCCGCGTTCTCTTTAAGAGGACTCCTTTTGCCTCCGCCGACCCCTTCG
	CTTCCGCTCCGCGTTCCCACAATGCAGTGCGGCTGAGCGCCTCGGAGCCC
	GCGGGGACGCTGCGGGGGGACCCGTGCTGAggcggcggcggcgacgtggg
	ctgcggcgggcccgcggcgtcgggcggtgcggatgtcgggctgggcggac
	gagcgcggcggcgAGGGCGACGGGCGCATCTACGTGGGGAACCTTCCGAC
	CGACGTGCGCGAGAAGGACTTGGAGGACCTGTTCTACAAGTACGGCCGCA
	TCCGCGAGATCGAGCTCAAGAACCGGCACGGCCTCGTGCCCTTCGCCTTC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGTGCGCTTCGAGGACCCCCGGTGAGGcccccgcgcccctgccct
	ctcctcctcggtgcctgaggcccccgccttccctgctgtcccctccccca
	gggctcccctccccccggcctcccctccccccgcctcegcgcagacccct
	caCGGCGCCCCCTCACGGGTGGAGGATGAGGCAGCCTCTCCTCGCAGGCC
	CGGGCCGTCCTTCGCGCCGTCGTCACTTCCTTTATTTTTATTATTCCAAT
	ATTTTACTTAGAAACCCAAAAGCTGAGCCTTTGGAGGGCCCAAGCCCGCC
	TGCACCGGCCTCGGGGGGTCCAAATGAGCCTTGTCCGCCTCCTGCCTGGG
	GCAGCACCGTAGGGGGAAGCGGCCGCGGGGCAGCGCGGGGGTCGCCGTTC
	GCCCTTCCCGCTCGCCTCTCCCCCGGCCCGTGCTCGCCGTGGCTGGAGAG
	CAAGCT
	(SEQ ID NO: 182)

pARBI-963:	GTAACTGACTAGCCTTAGTAGACTGTGGTTTCCAGGTTTATTCAGAAGTA	1806
SUB1_1_	GCAAGATCCCTCCAtttttttttCTACCAAAGAAATCGTATGTGGGATCC
Endogenous_70	CAAACCACAAAATAACCGTTCCTGTGGTTAATACTACTATAATGCCTGAA
	GTGTCTTTTGGGATCCTGAGAACAGAGTTTGAAAACATTACTAGACAGAA
	GGATTGGTTAGATTCATAGTTTTGTTGTTGAGTGAAACTTGCTTATGTAT
	ATATTTATGATATTTTGGATGTAGTCTTTTGATTGTTTAAATCTTAAAAA
	GTAATGGGATCTTTTGACACTGGGGTATGTTTTATTTTTATGTGTGCAAA
	TTTTAACCATATTCTTTTCTAGTTAAAGAGGAAAAAGCAAGTTGCTCCAG
	AAAAACCTGTAAAGAAACAAAAGACAGGTGAGACTTCGAGAGCCCTGTCA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTCTTCTAAACAGAGCAGCAGCAGCAGAGATGATAACATGTTTCA
	GGTAAAGTTGGCTAttttttttttttttttttttgacatggagtcatgct
	ctgtcacccaggctggagtgcagtggcgccatctcggctcactgcaacct
	cagcctcctgagttcaagcagttctctgcctcagcctcccgagtagctag
	gattacaggcatccgccaccagacctggctaatttttgtatttttagtag
	agatggggtttcaccatcttggccaggctggtcttgaactcctgaccttg
	tgatccaactgcctcagcctccaaaagtgctgggtttacaggtgtgagcc
	accatgccttgccAAAGTTGGCTGTTTCTTTAGATTCAGAGGAATTATTA
	TCTGGCTTGATCTGAAGAATGTTAAAAGTACTATGATCTGATAATTGCCT
	AATATG
	(SEQ ID NO: 183)

pARBI-964:	ATAAATAAACATATCCTGGAAATGGAATAAGTTGGTTATATTCTTTTTAA	1806
SUB1_2_	TTAGTATATCTGCTTCGTAAAATAAGTAACTGACTAGCCTTAGTAGACTG
Endogenous_71	TGGTTTCCAGGTTTATTCAGAAGTAGCAAGATCCCTCCATTTTTTTTTCT
	ACCAAAGAAATCGTATGTGGGATCCCAAACCACAAAATAACCGTTCCTGT
	GGTTAATACTACTATAATGCCTGAAGTGTCTTTTGGGATCCTGAGAACAG
	AGTTTGAAAACATTACTAGACAGAAGGATTGGTTAGATTCATAGTTTTGT
	TGTTGAGTGAAACTTGCTTATGTATATATTTATGATATTTTGGATGTAGT
	CTTTTGATTGTTTAAATCTTAAAAAGTAATGGGATCTTTTGACACTGGGG
	TATGTTTTATTTTTATGTGTGCAAATTTTAACCATATTCTTTTCTAGTTA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatAAGAGGAAAAAGCAAGTTGCTCCAGAAAAACCTGTAAAGAAACA
	AAAGACAGGTGAGACTTCGAGAGCCCTGTCATCTTCTAAACAGAGCAGCA
	GCAGCAGAGATGATAACATGTTTCAGGTAAAGTTGGCTATTTTTTTTTTT
	TTTTTTTTTGACATGGAGTCATGCTCTGTCACCCAGGCTGGAGTGCAGTG
	GCGCCATCTCGGCTCACTGCAACCTCAGCCTCCTGAGTTCAAGCAGTTCT
	CTGCCTCAGCCTCCCGAGTAGCTAGGATTACAGGCATCCGCCACCAGACC
	TGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCA
	GGCTGGTCTTGAACTCCTGACCTTGTGATCCAACTGCCTCAGCCTCCAAA
	AGTGCTGGGTTTACAGGTGTGAGCCACCATGCCTTGCCAAAGTTGGCTGT
	TTCTTT
	(SEQ ID NO: 184)

pARBI-965:	AATTAGTATATCTGCTTCGTAAAATAAGTAACTGACTAGCCTTAGTAGAC	1806
SUB1_3_	TGTGGTTTCCAGGTTTATTCAGAAGTAGCAAGATCCCTCCATTTTTTTTT
Endogenous_72	CTACCAAAGAAATCGTATGTGGGATCCCAAACCACAAAATAACCGTTCCT
	GTGGTTAATACTACTATAATGCCTGAAGTGTCTTTTGGGATCCTGAGAAC
	AGAGTTTGAAAACATTACTAGACAGAAGGATTGGTTAGATTCATAGTTTT
	GTTGTTGAGTGAAACTTGCTTATGTATATATTTATGATATTTTGGATGTA
	GTCTTTTGATTGTTTAAATCTTAAAAAGTAATGGGATCTTTTGACACTGG
	GGTATGTTTTATTTTTATGTGTGCAAATTTTAACCATATTCTTTTCTAGT
	TAAAGAGGAAAAAGCAAGTTGCTCCAGAAAAACCTGTAAAGAAACAAAAG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatACAGGTGAGACTTCGAGAGCCCTGTCATCTTCTAAACAGAGCAG
	CAGCAGCAGAGATGATAACATGTTTCAGGTAAAGTTGGCTATTTTTTTTT
	TTTTTTTTTTTGACATGGAGTCATGCTCTGTCACCCAGGCTGGAGTGCAG
	TGGCGCCATCTCGGCTCACTGCAACCTCAGCCTCCTGAGTTCAAGCAGTT
	CTCTGCCTCAGCCTCCCGAGTAGCTAGGATTACAGGCATCCGCCACCAGA
	CCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATCTTGGC
	CAGGCTGGTCTTGAACTCCTGACCTTGTGATCCAACTGCCTCAGCCTCCA
	AAAGTGCTGGGTTTACAGGTGTGAGCCACCATGCCTTGCCAAAGTTGGCT
	GTTTCTTTAGATTCAGAGGAATTATTATCTGGCTTGATCTGAAGAATGTT
	AAAAGT
	(SEQ ID NO: 185)

pARBI-966:	CACATTTTAATTTTTGTTTCCATGCTCTTTAGAATTCAACTAGAGGGCAG	1806
TET2_1_	CCTTGTGGATGGCCCCGAAGCAAGCCTGATGGAACAGGATAGAACCAACC
Endogenous_73	ATGTTGAGGGCAACAGACTAAGTCCATTCCTGATACCATCACCTCCCATT
	TGCCAGACAGAACCTCTGGCTACAAAGCTCCAGAATGGAAGCCCACTGCC
	TGAGAGAGCTCATCCAGAAGTAAATGGAGACACCAAGTGGCACTCTTTCA
	AAAGTTATTATGGAATACCCTGTATGAAGGGAAGCCAGAATAGTCGTGTG
	AGTCCTGACTTTACACAAGAAAGTAGAGGGTATTCCAAGTGTTTGCAAAA
	TGGAGGAATAAAACGCACAGTTAGTGAACCTTCTCTCTCTGGGCTCCTTC
	AGATCAAGAAATTGAAACAAGACCAAAAGGCTAATGGAGAAAGACGTAAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTTCGGGGTAAGCCAAGAAAGAAATCCAGGTGAAAGCAGTCAACC
	AAATGTCTCCGATTTGAGTGATAAGAAAGAATCTGTGAGTTCTGTAGCCC
	AAGAAAATGCAGTTAAAGATTTCACCAGTTTTTCAACACATAACTGCAGT
	GGGCCTGAAAATCCAGAGCTTCAGATTCTGAATGAGCAGGAGGGGAAAAG
	TGCTAATTACCATGACAAGAACATTGTATTACTTAAAAACAAGGCAGTGC
	TAATGCCTAATGGTGCTACAGTTTCTGCCTCTTCCGTGGAACACACACAT
	GGTGAACTCCTGGAAAAAACACTGTCTCAATATTATCCAGATTGTGTTTC
	CATTGCGGTGCAGAAAACCACATCTCACATAAATGCCATTAACAGTCAGG
	CTACTAATGAGTTGTCCTGTGAGATCACTCACCCATCGCATACCTCAGGG
	CAGATC
	(SEQ ID NO: 186)

pARBI-967:	AATGGAGAAAGACGTAACTTCGGGGTAAGCCAAGAAAGAAATCCAGGTGA	1806
TET2_2_	AAGCAGTCAACCAAATGTCTCCGATTTGAGTGATAAGAAAGAATCTGTGA
Endogenous_74	GTTCTGTAGCCCAAGAAAATGCAGTTAAAGATTTCACCAGTTTTTCAACA
	CATAACTGCAGTGGGCCTGAAAATCCAGAGCTTCAGATTCTGAATGAGCA
	GGAGGGGAAAAGTGCTAATTACCATGACAAGAACATTGTATTACTTAAAA
	ACAAGGCAGTGCTAATGCCTAATGGTGCTACAGTTTCTGCCTCTTCCGTG
	GAACACACACATGGTGAACTCCTGGAAAAAACACTGTCTCAATATTATCC
	AGATTGTGTTTCCATTGCGGTGCAGAAAACCACATCTCACATAAATGCCA
	TTAACAGTCAGGCTACTAATGAGTTGTCCTGTGAGATCACTCACCCATCG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCATACCTCAGGGCAGATCAATTCCGCACAGACCTCTAACTCTGA
	GCTGCCTCCAAAGCCAGCTGCAGTGGTGAGTGAGGCCTGTGATGCTGATG
	ATGCTGATAATGCCAGTAAACTAGCTGCAATGCTAAATACCTGTTCCTTT
	CAGAAACCAGAACAACTACAACAACAAAAATCAGTTTTTGAGATATGCCC
	ATCTCCTGCAGAAAATAACATCCAGGGAACCACAAAGCTAGCGTCTGGTG
	AAGAATTCTGTTCAGGTTCCAGCAGCAATTTGCAAGCTCCTGGTGGCAGC
	TCTGAACGGTATTTAAAACAAAATGAAATGAATGGTGCTTACTTCAAGCA
	AAGCTCAGTGTTCACTAAGGATTCCTTTTCTGCCACTACCACACCACCAC
	CACCATCACAATTGCTTCTTTCTCCCCCTCCTCCTCTTCCACAGGTTCCT
	CAGCTT
	(SEQ ID NO: 187)

pARBI-968:	GGAAAAAGCACTCTGAATGGTGGAGTTTTAGAAGAACACCACCACTACCC	1806
TET2_3_	CAACCAAAGTAACACAACACTTTTAAGGGAAGTGAAAATAGAGGGTAAAC
Endogenous_75	CTGAGGCACCACCTTCCCAGAGTCCTAATCCATCTACACATGTATGCAGC
	CCTTCTCCGATGCTTTCTGAAAGGCCTCAGAATAATTGTGTGAACAGGAA
	TGACATACAGACTGCAGGGACAATGACTGTTCCATTGTGTTCTGAGAAAA
	CAAGACCAATGTCAGAACACCTCAAGCATAACCCACCAATTTTTGGTAGC
	AGTGGAGAGCTACAGGACAACTGCCAGCAGTTGATGAGAAACAAAGAGCA
	AGAGATTCTGAAGGGTCGAGACAAGGAGCAAACACGAGATCTTGTGCCCC
	CAACACAGCACTATCTGAAACCAGGATGGATTGAATTGAAGGCCCCTCGT
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTTTCACCAAGCGGAATCCCATCTAAAACGTAATGAGGCATCACT
	GCCATCAATTCTTCAGTATCAACCCAATCTCTCCAATCAAATGACCTCCA
	AACAATACACTGGAAATTCCAACATGCCTGGGGGGCTCCCAAGGCAAGCT
	TACACCCAGAAAACAACACAGCTGGAGCACAAGTCACAAATGTACCAAGT
	TGAAATGAATCAAGGGCAGTCCCAAGGTACAGTGGACCAACATCTCCAGT
	TCCAAAAACCCTCACACCAGGTGCACTTCTCCAAAACAGACCATTTACCA
	AAAGCTCATGTGCAGTCACTGTGTGGCACTAGATTTCATTTTCAACAAAG
	AGCAGATTCCCAAACTGAAAAACTTATGTCCCCAGTGTTGAAACAGCACT
	TGAATCAACAGGCTTCAGAGACTGAGCCATTTTCAAACTCACACCTTTTG
	CAACAT
	(SEQ ID NO: 188)

pARBI-969:	AAAGGGAGGTTGAGATGGGCTGAGGTCTTCTAGGAGGCGGGGAGGGAGTG	1806
TIGIT_1_	CAGCCTTGACAAGCCTCCCTGTGGGCGAGGTGTAAAGAGGGGCAGAAGTC
Endogenous_76	AGCTCTGGAAGCATAGGGCAGTGGGTGGGGAGGAGATGGGCTGGGCTGGG
	CTGGAGTAGAGATGTGTGGAGAAGGGTGAGAAGACTGGAAAGACAACCTG
	AATGGGGGACTGGGAGCCTTGAATAACAGGCATGGAGAGGAGCGTCTCTT
	GAAATGGAAGAAACAGGAAATAATTACAGCCTCTATGGAGGAGCAACAGG
	ATGGACTGGAGAAACTATCATTCCAAAATCCAGTTGGGGCCTCAAAGGCC
	CTTAGAATTTTTCTAGGAAGGTTGAAGGCCAGCTGCTGACCCAGGACTCA
	CATGTGCTTCGTCCTCTTCCCTAGGAATGATGACAGGCACAATAGAAACA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatACGGGGAACATTTCTGCAGAGAAAGGTGGCTCTATCATCTTACA
	ATGTCACCTCTCCTCCACCACGGCACAAGTGACCCAGGTCAACTGGGAGC
	AGCAGGACCAGCTTCTGGCCATTTGTAATGCTGACTTGGGGTGGCACATC
	TCCCCATCCTTCAAGGATCGAGTGGCCCCAGGTCCCGGCCTGGGCCTCAC
	CCTCCAGTCGCTGACCGTGAACGATACAGGGGAGTACTTCTGCATCTATC
	ACACCTACCCTGATGGGACGTACACTGGGAGAATCTTCCTGGAGGTCCTA
	GAAAGCTCAGGTATTCCTGCTGGAGCAAGTTGGTGGATAAACCTCTCCCT
	CTAGCATAGAAAATGCAATCCTGAAACACTGCACAGCAGGGCTTCTCAAT
	TCGGGATCACATTTGAATCACCTGAGGAGATTTTAAATCATACTGATGCC
	GAGGCC
	(SEQ ID NO: 189)

pARBI-970:	GAGGAGATGGGCTGGGCTGGGCTGGAGTAGAGATGTGTGGAGAAGGGTGA	1806
TIGIT_2_	GAAGACTGGAAAGACAACCTGAATGGGGGACTGGGAGCCTTGAATAACAG
Endogenous_77	GCATGGAGAGGAGCGTCTCTTGAAATGGAAGAAACAGGAAATAATTACAG
	CCTCTATGGAGGAGCAACAGGATGGACTGGAGAAACTATCATTCCAAAAT
	CCAGTTGGGGCCTCAAAGGCCCTTAGAATTTTTCTAGGAAGGTTGAAGGC
	CAGCTGCTGACCCAGGACTCACATGTGCTTCGTCCTCTTCCCTAGGAATG
	ATGACAGGCACAATAGAAACAACGGGGAACATTTCTGCAGAGAAAGGTGG
	CTCTATCATCTTACAATGTCACCTCTCCTCCACCACGGCACAAGTGACCC
	AGGTCAACTGGGAGCAGCAGGACCAGCTTCTGGCCATTTGTAATGCTGAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTTGGGGTGGCACATCTCCCCATCCTTCAAGGATCGAGTGGCCCC
	AGGTCCCGGCCTGGGCCTCACCCTCCAGTCGCTGACCGTGAACGATACAG
	GGGAGTACTTCTGCATCTATCACACCTACCCTGATGGGACGTACACTGGG
	AGAATCTTCCTGGAGGTCCTAGAAAGCTCAGGTATTCCTGCTGGAGCAAG
	TTGGTGGATAAACCTCTCCCTCTAGCATAGAAAATGCAATCCTGAAACAC
	TGCACAGCAGGGCTTCTCAATTCGGGATCACATTTGAATCACCTGAGGAG
	ATTTTAAATCATACTGATGCCGAGGCCTCACCCAGACCAATTCAATCAGA
	ATCCCTAATAGCAGAGCTAAACAAGGGTAAGGTCTAAAAGCATTTCCAGG
	TGATTCTAATGGGCAGCCAATACTGAGAACCACTGTTCTTATGTAAGAAG
	CACATC
	(SEQ ID NO: 190)

pARBI-971:	CCTCCCTGTGGGCGAGGTGTAAAGAGGGGCAGAAGTCAGCTCTGGAAGCA	1806
TIGIT_3_	TAGGGCAGTGGGTGGGGAGGAGATGGGCTGGGCTGGGCTGGAGTAGAGAT
Endogenous_78	GTGTGGAGAAGGGTGAGAAGACTGGAAAGACAACCTGAATGGGGGACTGG
	GAGCCTTGAATAACAGGCATGGAGAGGAGCGTCTCTTGAAATGGAAGAAA
	CAGGAAATAATTACAGCCTCTATGGAGGAGCAACAGGATGGACTGGAGAA
	ACTATCATTCCAAAATCCAGTTGGGGCCTCAAAGGCCCTTAGAATTTTTC
	TAGGAAGGTTGAAGGCCAGCTGCTGACCCAGGACTCACATGTGCTTCGTC
	CTCTTCCCTAGGAATGATGACAGGCACAATAGAAACAACGGGGAACATTT
	CTGCAGAGAAAGGTGGCTCTATCATCTTACAATGTCACCTCTCCTCCACC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatACGGCACAAGTGACCCAGGTCAACTGGGAGCAGCAGGACCAGCT
	TCTGGCCATTTGTAATGCTGACTTGGGGTGGCACATCTCCCCATCCTTCA
	AGGATCGAGTGGCCCCAGGTCCCGGCCTGGGCCTCACCCTCCAGTCGCTG
	ACCGTGAACGATACAGGGGAGTACTTCTGCATCTATCACACCTACCCTGA
	TGGGACGTACACTGGGAGAATCTTCCTGGAGGTCCTAGAAAGCTCAGGTA
	TTCCTGCTGGAGCAAGTTGGTGGATAAACCTCTCCCTCTAGCATAGAAAA
	TGCAATCCTGAAACACTGCACAGCAGGGCTTCTCAATTCGGGATCACATT
	TGAATCACCTGAGGAGATTTTAAATCATACTGATGCCGAGGCCTCACCCA
	GACCAATTCAATCAGAATCCCTAATAGCAGAGCTAAACAAGGGTAAGGTC
	TAAAAG
	(SEQ ID NO: 191)

pARBI-972:	TAATGCCCAGCCTAAGTTGGGGAGACCACTCCAGATTCCAAGATGTACAG	1806
TRAC_1_	TTTGCTTTGCTGGGCCTTTTTCCCATGCCTGCCTTTACTCTGCCAGAGTT
Endogenous_79	ATATTGCTGGGGTTTTGAAGAAGATCCTATTAAATAAAAGAATAAGCAGT
	ATTATTAAGTAGCCCTGCATTTCAGGTTTCCTTGAGTGGCAGGCCAGGCC
	TGGCCGTGAACGTTCACTGAAATCATGGCCTCTTGGCCAAGATTGATAGC
	TTGTGCCTGTCCCTGAGTCCCAGTCCATCACGAGCAGCTGGTTTCTAAGA
	TGCTATTTCCCGTATAAAGCATGAGACCGTGACTTGCCAGCCCCACAGAG
	CCCCGCCCTTGTCCATCACTGGCATCTGGACTCCAGCCTGGGTTGGGGCA
	AAGAGGGAAATGAGATCATGTCCTAACCCTGATCCTCTTGTCCCACAGAT
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatATCCAGAACCCTGACCCTGCCGTGTACCAGCTGAGAGACTCTAA
	ATCCAGTGACAAGTCTGTCTGCCTATTCACCGATTTTGATTCTCAAACAA
	ATGTGTCACAAAGTAAGGATTCTGATGTGTATATCACAGACAAAACTGTG
	CTAGACATGAGGTCTATGGACTTCAAGAGCAACAGTGCTGTGGCCTGGAG
	CAACAAATCTGACTTTGCATGTGCAAACGCCTTCAACAACAGCATTATTC
	CAGAAGACACCTTCTTCCCCAGCCCAGGTAAGGGCAGCTTTGGTGCCTTC
	GCAGGCTGTTTCCTTGCTTCAGGAATGGCCAGGTTCTGCCCAGAGCTCTG
	GTCAATGATGTCTAAAACTCCTCTGATTGGTGGTCTCGGCCTTATCCATT
	GCCACCAAAACCCTCTTTTTACTAAGAAACAGTGAGCCTTGTTCTGGCAG
	TCCAGA
	(SEQ ID NO: 192)

pARBI-973:	GATTCCAAGATGTACAGTTTGCTTTGCTGGGCCTTTTTCCCATGCCTGCC	1806
TRAC_2_	TTTACTCTGCCAGAGTTATATTGCTGGGGTTTTGAAGAAGATCCTATTAA
Endogenous_80	ATAAAAGAATAAGCAGTATTATTAAGTAGCCCTGCATTTCAGGTTTCCTT
	GAGTGGCAGGCCAGGCCTGGCCGTGAACGTTCACTGAAATCATGGCCTCT
	TGGCCAAGATTGATAGCTTGTGCCTGTCCCTGAGTCCCAGTCCATCACGA
	GCAGCTGGTTTCTAAGATGCTATTTCCCGTATAAAGCATGAGACCGTGAC
	TTGCCAGCCCCACAGAGCCCCGCCCTTGTCCATCACTGGCATCTGGACTC
	CAGCCTGGGTTGGGGCAAAGAGGGAAATGAGATCATGTCCTAACCCTGAT
	CCTCTTGTCCCACAGATATCCAGAACCCTGACCCTGCCGTGTACCAGCTG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatAGAGACTCTAAATCCAGTGACAAGTCTGTCTGCCTATTCACCGA
	TTTTGATTCTCAAACAAATGTGTCACAAAGTAAGGATTCTGATGTGTATA
	TCACAGACAAAACTGTGCTAGACATGAGGTCTATGGACTTCAAGAGCAAC
	AGTGCTGTGGCCTGGAGCAACAAATCTGACTTTGCATGTGCAAACGCCTT
	CAACAACAGCATTATTCCAGAAGACACCTTCTTCCCCAGCCCAGGTAAGG
	GCAGCTTTGGTGCCTTCGCAGGCTGTTTCCTTGCTTCAGGAATGGCCAGG
	TTCTGCCCAGAGCTCTGGTCAATGATGTCTAAAACTCCTCTGATTGGTGG
	TCTCGGCCTTATCCATTGCCACCAAAACCCTCTTTTTACTAAGAAACAGT
	GAGCCTTGTTCTGGCAGTCCAGAGAATGACACGGGAAAAAAGCAGATGAA
	GAGAAG
	(SEQ ID NO: 193)

pARBI-974:	TTCCTGTGGTAGCGGAACTCACTAAGGGGCCCATCTGGACCCGAGGTATT	1806
TRAC_3_	GTGATGATAAATTCTGAGCACCTACCCCATCCCCAGAAGGGCTCAGAAAT
Endogenous_81	AAAATAAGAGCCAAGTCTAGTCGGTGTTTCCTGTCTTGAAACACAATACT
	GTTGGCCCTGGAAGAATGCACAGAATCTGTTTGTAAGGGGATATGCACAG
	AAGCTGCAAGGGACAGGAGGTGCAGGAGCTGCAGGCCTCCCCCACCCAGC
	CTGCTCTGCCTTGGGGAAAACCGTGGGTGTGTCCTGCAGGCCATGCAGGC
	CTGGGACATGCAAGCCCATAACCGCTGTGGCCTCTTGGTTTTACAGATAC
	GAACCTAAACTTTCAAAACCTGTCAGTGATTGGGTTCCGAATCCTCCTCC
	TGAAAGTGGCCGGGTTTAATCTGCTCATGACGCTGCGGCTGTGGTCCAGC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTGAGGTGAGGGGCCTTGAAGCTGGGAGTGGGGTTTAGGGACGCG
	GGTCTCTGGGTGCATCCTAAGCTCTGAGAGCAAACCTCCCTGCAGGGTCT
	TGCTTTTAAGTCCAAAGCCTGAGCCCACCAAACTCTCCTACTTCTTCCTG
	TTACAAATTCCTCTTGTGCAATAATAATGGCCTGAAACGCTGTAAAATAT
	CCTCATTTCAGCCGCCTCAGTTGCACTTCTCCCCTATGAGGTAGGAAGAA
	CAGTTGTTTAGAAACGAAGAAACTGAGGCCCCACAGCTAATGAGTGGAGG
	AAGAGAGACACTTGTGTACACCACATGCCTTGTGTTGTACTTCTCTCACC
	GTGTAACCTCCTCATGTCCTCTCTCCCCAGTACGGCTCTCTTAGCTCAGT
	AGAAAGAAGACATTACACTCATATTACACCCCAATCCTGGCTAGAGTCTC
	CGCACC
	(SEQ ID NO: 194)

pARBI-975:	ATTATTAAGTAGCCCTGCATTTCAGGTTTCCTTGAGTGGCAGGCCAGGCC	1806
TRAC_4_	TGGCCGTGAACGTTCACTGAAATCATGGCCTCTTGGCCAAGATTGATAGC
Endogenous_82	TTGTGCCTGTCCCTGAGTCCCAGTCCATCACGAGCAGCTGGTTTCTAAGA
	TGCTATTTCCCGTATAAAGCATGAGACCGTGACTTGCCAGCCCCACAGAG
	CCCCGCCCTTGTCCATCACTGGCATCTGGACTCCAGCCTGGGTTGGGGCA
	AAGAGGGAAATGAGATCATGTCCTAACCCTGATCCTCTTGTCCCACAGAT
	ATCCAGAACCCTGACCCTGCCGTGTACCAGCTGAGAGACTCTAAATCCAG
	TGACAAGTCTGTCTGCCTATTCACCGATTTTGATTCTCAAACAAATGTGT
	CACAAAGTAAGGATTCTGATGTGTATATCACAGACAAAACTGTGCTAGAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatATGAGGTCTATGGACTTCAAGAGCAACAGTGCTGTGGCCTGGAG
	CAACAAATCTGACTTTGCATGTGCAAACGCCTTCAACAACAGCATTATTC
	CAGAAGACACCTTCTTCCCCAGCCCAGGTAAGGGCAGCTTTGGTGCCTTC
	GCAGGCTGTTTCCTTGCTTCAGGAATGGCCAGGTTCTGCCCAGAGCTCTG
	GTCAATGATGTCTAAAACTCCTCTGATTGGTGGTCTCGGCCTTATCCATT
	GCCACCAAAACCCTCTTTTTACTAAGAAACAGTGAGCCTTGTTCTGGCAG
	TCCAGAGAATGACACGGGAAAAAAGCAGATGAAGAGAAGGTGGCAGGAGA
	GGGCACGTGGCCCAGCCTCAGTCTCTCCAACTGAGTTCCTGCCTGCCTGC
	CTTTGCTCAGACTGTTTGCCCCTTACTGCTCTTCTAGGCCTCATTCTAAG
	CCCCTT
	(SEQ ID NO: 195)

pARBI-976:	TTCATTTCCATTTGAGTTGTTCTTATTGAGTCATCCTTCCTGTGGTAGCG	1806
TRAC_6_	GAACTCACTAAGGGGCCCATCTGGACCCGAGGTATTGTGATGATAAATTC
Endogenous_84	TGAGCACCTACCCCATCCCCAGAAGGGCTCAGAAATAAAATAAGAGCCAA
	GTCTAGTCGGTGTTTCCTGTCTTGAAACACAATACTGTTGGCCCTGGAAG
	AATGCACAGAATCTGTTTGTAAGGGGATATGCACAGAAGCTGCAAGGGAC
	AGGAGGTGCAGGAGCTGCAGGCCTCCCCCACCCAGCCTGCTCTGCCTTGG
	GGAAAACCGTGGGTGTGTCCTGCAGGCCATGCAGGCCTGGGACATGCAAG
	CCCATAACCGCTGTGGCCTCTTGGTTTTACAGATACGAACCTAAACTTTC
	AAAACCTGTCAGTGATTGGGTTCCGAATCCTCCTCCTGAAAGTGGCCGGG
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatTTTAATCTGCTCATGACGCTGCGGCTGTGGTCCAGCTGAGGTGA
	GGGGCCTTGAAGCTGGGAGTGGGGTTTAGGGACGCGGGTCTCTGGGTGCA
	TCCTAAGCTCTGAGAGCAAACCTCCCTGCAGGGTCTTGCTTTTAAGTCCA
	AAGCCTGAGCCCACCAAACTCTCCTACTTCTTCCTGTTACAAATTCCTCT
	TGTGCAATAATAATGGCCTGAAACGCTGTAAAATATCCTCATTTCAGCCG
	CCTCAGTTGCACTTCTCCCCTATGAGGTAGGAAGAACAGTTGTTTAGAAA
	CGAAGAAACTGAGGCCCCACAGCTAATGAGTGGAGGAAGAGAGACACTTG
	TGTACACCACATGCCTTGTGTTGTACTTCTCTCACCGTGTAACCTCCTCA
	TGTCCTCTCTCCCCAGTACGGCTCTCTTAGCTCAGTAGAAAGAAGACATT
	ACACTC
	(SEQ ID NO: 196)

pARBI-977:	CAGTCCATCACGAGCAGCTGGTTTCTAAGATGCTATTTCCCGTATAAAGC	1806
TRAC_	ATGAGACCGTGACTTGCCAGCCCCACAGAGCCCCGCCCTTGTCCATCACT
Endogenous_83	GGCATCTGGACTCCAGCCTGGGTTGGGGCAAAGAGGGAAATGAGATCATG
	TCCTAACCCTGATCCTCTTGTCCCACAGATATCCAGAACCCTGACCCTGC
	CGTGTACCAGCTGAGAGACTCTAAATCCAGTGACAAGTCTGTCTGCCTAT
	TCACCGATTTTGATTCTCAAACAAATGTGTCACAAAGTAAGGATTCTGAT
	GTGTATATCACAGACAAAACTGTGCTAGACATGAGGTCTATGGACTTCAA
	GAGCAACAGTGCTGTGGCCTGGAGCAACAAATCTGACTTTGCATGTGCAA
	ACGCCTTCAACAACAGCATTATTCCAGAAGACACCTTCTTCCCCAGCCCA
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGGTAAGGGCAGCTTTGGTGCCTTCGCAGGCTGTTTCCTTGCTTC
	AGGAATGGCCAGGTTCTGCCCAGAGCTCTGGTCAATGATGTCTAAAACTC
	CTCTGATTGGTGGTCTCGGCCTTATCCATTGCCACCAAAACCCTCTTTTT
	ACTAAGAAACAGTGAGCCTTGTTCTGGCAGTCCAGAGAATGACACGGGAA
	AAAAGCAGATGAAGAGAAGGTGGCAGGAGAGGGCACGTGGCCCAGCCTCA
	GTCTCTCCAACTGAGTTCCTGCCTGCCTGCCTTTGCTCAGACTGTTTGCC
	CCTTACTGCTCTTCTAGGCCTCATTCTAAGCCCCTTCTCCAAGTTGCCTC
	TCCTTATTTCTCCCTGTCTGCCAAAAAATCTTTCCCAGCTCACTAAGTCA
	GTCTCACGCAGTCACTCATTAACCCACCAATCACTGATTGTGCCGGCACA
	TGAATG
	(SEQ ID NO: 197)

pARBI-978:	TGAGGAAGAAGCGCGGGCGGCGCCTTCGGGAGGCGAGCAGGCAGCAGTTG	1806
TRIM28_1_	GCCGTGCCGTAGCAGCGTCCCGCGCGCGGCGGGCAGCGGCCCAGGAGGCG
Endogenous_85	CGTGGCGGCGCTCGGCCTCGCGGCGGCGGCGGCGGCAGCGGCCCAGCAGT
	TGGCGGCGAGCGCGTCTGCGCCTGCGCGGCGGGCCCCGCGCCCCTCCTCC
	CCCCCTGGGCGCCCCCGGCGGCGTGTGAATGGCGGCCTCCGCGGCGGCAG
	CCTCGGCAGCAGCGGCCTCGGCCGCCTCTGGCAGCCCGGGCCCGGGCGAG
	GGCTCCGCTGGCGGCGAAAAGCGCTCCACCGCCCCTTCGGCCGCAGCCTC
	GGCCTCTGCCTCAGCCGCGGCGTCGTCGCCCGCGGGGGGCGGCGCCGAGG
	CGCTGGAGCTGCTGGAGCACTGCGGCGTGTGCAGAGAGCGCCTGCGACCC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGAGAGGGAGCCCCGCCTGCTGCCCTGTTTGCACTCGGCCTGTAG
	TGCCTGCTTAGGGCCCGCGGCCCCCGCCGCCGCCAACAGCTCGGGGGACG
	GCGGGGCGGCGGGCGACGGCACCGGTAAGTACGAAGTGATCGGTGCCACC
	CCTCCCCCTACTCTCTGCCTTTGATTCCGACTGGGTGCAGAGATGAGGAT
	GCCACCTGGGCGAGAGGATGGGGGCCCGGACAGGGCACGGGAAATACTTT
	CTGGGTCCTGCATACGAACGTGGGTTTGTGCTGGCCGCTGAGATGGGACA
	TCTGACTAAAGTTGGAGAAAAGAAGGCTCGGGGAGGGGAGGGGCTGGTTC
	GCTGCGGGATAATGGTCGGGGGCCCACCCAGCAGGGGAATGGTGGGGGCC
	ATAACCTGGGTGGGAACTTGTAACAGTCTCCCACATCCCTGCTTCTCGAA
	GTGGTG
	(SEQ ID NO: 198)

pARBI-979:	TCGAAGTGGTGGACTGTCCCGTGTGCAAGCAACAGTGCTTCTCCAAAGAC	1806
TRIM28_2_	ATCGTGGAGAATTATTTCATGCGTGATAGTGGCAGCAAGGCTGCCACCGA
Endogenous_86	CGCCCAGGATGCGAACCAGGTGCGTCCTATCTCAGCAACCACAAGGAGGT
	TTCTGGGGAGGGGGCATCTGCGCAGGAGGAGCTTGGCACCAGCTCCAGGC
	TGTTACTCCACTTTCCCAAGGCTCTGGGTGGGCTGCCTAGGTTGGGTCAA
	GGGACCAATCTTAAATCTCCGGTTGTATTTTCTGGGATGTAAACGTGGAT
	CTATCAAGTIGTCTTGCCTTCTCTGACCCTGCCTTTGTCTGGCAGTGCTG
	CACTAGCTGTGAGGATAATGCCCCAGCCACCAGCTACTGTGTGGAGTGCT
	CGGAGCCTCTGTGTGAGACCTGTGTAGAGGCGCACCAGCGGGTGAAGTAC
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatACCAAGGACCATACTGTGCGCTCTACTGGTACATGAGGCTGAGG
	GGGGCTGTTGGAGTTGTTCTCCCATGTGTGCCCTCAGTTGCTTTTATGAT
	GTTGGTTGCATCTGGTGGATGGGTCCTAGAGTTCTCTAGGGGGTGCCGCC
	CGAAGGGCCCGAGGGCAGAACTCCAGAAGCAGAAAAACTGGGGTTGTGGT
	GTGTAGTCTCTAGGGCCTAGGTGGGAGAGGGTGGGAAGGGGAAATAAGGG
	AGACCTTAATGTGCTGCAGGGAGGTACAAAGGGTTTGAGAAGGCTTATCA
	GGGAGTTGTCAGACCTGGTGGTGAAGGGCTCAGCATATGCAAACAGGGAA
	AGGCATGGTGTGAAGGGCTTTCTGGGTTTGTGGTTCCCTGGCACACATCT
	GGTATAAGATGCTGCTAGGGAAAGTAGACTGTGGGTCCATGGATTATAAG
	TGATGA
	(SEQ ID NO: 199)

pARBI-980:	GGCGCCCAATGCGCGTGCGCGGCGGCGTCGGCGCCAGTTATTTCTGTCCC	1806
TRIM28_3_	GCCCCCCGGCCTCGGCTCTTTCTGCGAGCGGGCGCGCGGGCGAGCGGTTG
EndogenouS_87	TGCTTGTGCTTGTGGCGCGTGGTGCGGGTTTCGGCGGCGGCTGAGGAAGA
	AGCGCGGGCGGCGCCTTCGGGAGGCGAGCAGGCAGCAGTTGGCCGTGCCG
	TAGCAGCGTCCCGCGCGCGGCGGGCAGCGGCCCAGGAGGCGCGTGGCGGC
	GCTCGGCCTCGCGGCGGCGGCGGCGGCAGCGGCCCAGCAGTTGGCGGCGA
	GCGCGTCTGCGCCTGCGCGGCGGGCCCCGCGCCCCTCCTCCCCCCCTGGG
	CGCCCCCGGCGGCGTGTGAATGGCGGCCTCCGCGGCGGCAGCCTCGGCAG
	CAGCGGCCTCGGCCGCCTCTGGCAGCCCGGGCCCGGGCGAGGGCTCCGCT
	tccggatccggagagggcaggggatctctccttacttgtggcgacgtgga
	ggagaaccccggccccATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGG
	TGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGCCACAAGTTC
	AGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAAGCTGACCCT
	GAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCG
	TGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatGGCGGCGAAAAGCGCTCCACCGCCCCTTCGGCCGCAGCCTCGGC
	CTCTGCCTCAGCCGCGGCGTCGTCGCCCGCGGGGGGCGGCGCCGAGGCGC
	TGGAGCTGCTGGAGCACTGCGGCGTGTGCAGAGAGCGCCTGCGACCCGAG
	AGGGAGCCCCGCCTGCTGCCCTGTTTGCACTCGGCCTGTAGTGCCTGCTT
	AGGGCCCGCGGCCCCCGCCGCCGCCAACAGCTCGGGGGACGGCGGGGCGG
	CGGGCGACGGCACCGGTAAGTACGAAGTGATCGGTGCCACCCCTCCCCCT
	ACTCTCTGCCTTTGATTCCGACTGGGTGCAGAGATGAGGATGCCACCTGG
	GCGAGAGGATGGGGGCCCGGACAGGGCACGGGAAATACTTTCTGGGTCCT
	GCATACGAACGTGGGTTTGTGCTGGCCGCTGAGATGGGACATCTGACTAA
	AGTTGG
	(SEQ ID NO: 200)

pARBI-596:	ATCTCGGCCAATAAAGGAGAAAGGGCGCGGCCCGTACGCGCGCCAGGTGC	2541
APRT_1_	GTGGGCGAGACCAGCTCACGCCCCTCCTCCAGCCGCCAAGGCCCCGGCCC
Exogenous_1	ACAGCTGCCTGGCTGCAGTCAGAAGCGTAGCCCGAGACAAGGAAGGGCGC
	CTTGACTCGCACTTTTGTCCGGTTCGAACGTTCTGctcagtggtgcgtgg
	aatgcgagcgcgtcttaaaatcgatggcgcctaggagtccatgaaatacg
	gTACAGGCTTCCGGCGACGGATGCCCCGCCCCTCACCCACGCTCCGCCCT
	CCGGGGATGCCCCACCCCTCGTGGCGGTCCCGCCCGTCCCCGCGCAGGCG
	CGCTCGGGCTGCCGCTGGCTCTTCGCACGCGGCCATGGCCGACTCCGAGC
	TGCAGCTGGTTGAGCAGCGGATCCGCAGCTTCCCCGACTTCCCCACCCCA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatGGCGTGGTAT
	TCAGGTGCACGCACAGGCCGCCCTCGTGGCGCCCCGACCTGCGGGCCTAC
	GGATGGGAGCGCGTGGCCCGCGACCTCCGGGGGGCGGGGCGGGAACCCTC
	GTCTTTCGCCCCCGGGGCCCTGCCCTCCTTCGGCCCCGGCGTCACCAGGC
	CTGTCCTTGGGTCCAGGGACATCTCGCCCGTCCTGAAGGACCCCGCCTCC
	TTCCGCGCCGCCATCGGCCTCCTGGCGCGACACCTGAAGGCGACCCACGG
	GGGCCGCATCGACTACATCGCAGGCGAGTGCCCAGTGGCCGCATCTAGGG
	CGCTTCCGCCTCTGCGCGCGCCGAGGGCAGCACGTGGGCTCTGCGCGTCT
	GCTTGGGGGAGGGCCTTTGGGGTGCTTCAGGGGGCGCCGGGACGGGCGCC
	GTGCTTGGGTCGCCCGGGAAGGGTTGTGAGATTGAGCCC
	(SEQ ID NO: 201)

pARBI-597:	TGCCCCGCCCCTCACCCACGCTCCGCCCTCCGGGGATGCCCCACCCCTCG	2541
APRT_2_	TGGCGGTCCCGCCCGTCCCCGCGCAGGCGCGCTCGGGCTGCCGCTGGCTC
Exogenous_2	TTCGCACGCGGCCATGGCCGACTCCGAGCTGCAGCTGGTTGAGCAGCGGA
	TCCGCAGCTTCCCCGACTTCCCCACCCCAGGCGTGGTATTCAGGTGCACG
	CACAGGCCGCCCTCGTGGCGCCCCGACCTGCGGGCCTACGGATGGGAGCG
	CGTGGCCCGCGACCTCCGGGGGGGGGGGGCGGGAACCCTCGTCTTTCGCC
	CCCGGGGCCCTGCCCTCCTTCGGCCCCGGCGTCACCAGGCCTGTCCTTGG
	GTCCAGGGACATCTCGCCCGTCCTGAAGGACCCCGCCTCCTTCCGCGCCG
	CCATCGGCCTCCTGGCGCGACACCTGAAGGCGACCCACGGGGGCCGCATC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGACTACATC
	GCAGGCGAGTGCCCAGTGGCCGCATCTAGGGCGCTTCCGCCTCTGCGCGC
	GCCGAGGGCAGCACGTGGGCTCTGCGCGTCTGCTTGGGGGAGGGCCTTTG
	GGGTGCTTCAGGGGGCGCCGGGACGGGCGCCGTGCTTGGGTCGCCCGGGA
	AGGGTTGTGAGATTGAGCCCCCGAGGCCGCCGCGCTGTGCAGGCGTCCTT
	CCCGCAGGTTCCGGGTCCCCAGCCCAGGACAGGCGTGACCGAGTTGCCGG
	GTCAGTTGGTCTCCCTGGAGTGCCCAAGCTGAATCCACAGGGCCCAGCTG
	CCTTGCTTCTTGTTCCTTCTGCGAGCTGGTATTGAGCGCCTGCCACGAGC
	CAGGCCTTCCCTGGTGAAGATCACGGAATGCCCACCCAGGGAAGGGAGGC
	CTGGAGGCCTCCGGGAGAGCCCAAGAGGTGGCCCAGGGAGA
	(SEQ ID NO: 202)

pARBI-598:	CGTTCTGctcagtggtgcgtggaatgcgagcgcgtcttaaaatcgatggc	2541
APRT_3_	gcctaggagtccatgaaatacggTACAGGCTTCCGGCGACGGATGCCCCG
Exogenous_3	CCCCTCACCCACGCTCCGCCCTCCGGGGATGCCCCACCCCTCGTGGCGGT
	CCCGCCCGTCCCCGCGCAGGCGCGCTCGGGCTGCCGCTGGCTCTTCGCAC
	GCGGCCATGGCCGACTCCGAGCTGCAGCTGGTTGAGCAGCGGATCCGCAG
	CTTCCCCGACTTCCCCACCCCAGGCGTGGTATTCAGGTGCACGCACAGGC
	CGCCCTCGTGGCGCCCCGACCTGCGGGCCTACGGATGGGAGCGCGTGGCC
	CGCGACCTCCGGGCGGGCGGGGGGGGAACCCTCGTCTTTCGCCCCCGGGG
	CCCTGCCCTCCTTCGGCCCCGGCGTCACCAGGCCTGTCCTTGGGTCCAGG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatGACATCTCGC
	CCGTCCTGAAGGACCCCGCCTCCTTCCGCGCCGCCATCGGCCTCCTGGCG
	CGACACCTGAAGGCGACCCACGGGGGCCGCATCGACTACATCGCAGGCGA
	GTGCCCAGTGGCCGCATCTAGGGCGCTTCCGCCTCTGCGCGCGCCGAGGG
	CAGCACGTGGGCTCTGCGCGTCTGCTTGGGGGAGGGCCTTTGGGGTGCTT
	CAGGGGGCGCCGGGACGGGCGCCGTGCTTGGGTCGCCCGGGAAGGGTTGT
	GAGATTGAGCCCCCGAGGCCGCCGCGCTGTGCAGGCGTCCTTCCCGCAGG
	TTCCGGGTCCCCAGCCCAGGACAGGCGTGACCGAGTTGCCGGGTCAGTTG
	GTCTCCCTGGAGTGCCCAAGCTGAATCCACAGGGCCCAGCTGCCTTGCTT
	CTTGTTCCTTCTGCGAGCTGGTATTGAGCGCCTGCCACGA
	(SEQ ID NO: 203)

pARBI-599:	AGTAATTTGATGGGGGCTATTATGAACTGAGAAATGAACTTTGAAAAGTA	2541
B2M_1_	TCTTGGGGCCAAATCATGTAGACTCTTGAGTGATGTGTTAAGGAATGCTA
Exogenous_4	TGAGTGCTGAGAGGGCATCAGAAGTCCTTGAGAGCCTCCAGAGAAAGGCT
	CTTAAAAATGCAGCGCAATCTCCAGTGACAGAAGATACTGCTAGAAATCT
	GCTAGAAAAAAAACAAAAAAGGCATGTATAGAGGAATTATGAGGGAAAGA
	TACCAAGTCACGGTTTATTCTTCAAAATGGAGGTGGCTTGTTGGGAAGGT
	GGAAGCTCATTTGGCCAGAGTGGAAATGGAATTGGGAGAAATCGATGACC
	AAATGTAAACACTTGGTGCCTGATATAGCTTGACACCAAGTTAGCCCCAA
	GTGAAATACCCTGGCAATATTAATGTGTCTTTTCCCGATATTCCTCAGGT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatACTCCAAAG
	ATTCAGGTTTACTCACGTCATCCAGCAGAGAATGGAAAGTCAAATTTCCT
	GAATTGCTATGTGTCTGGGTTTCATCCATCCGACATTGAAGTTGACTTAC
	TGAAGAATGGAGAGAGAATTGAAAAAGTGGAGCATTCAGACTTGTCTTTC
	AGCAAGGACTGGTCTTTCTATCTCTTGTACTACACTGAATTCACCCCCAC
	TGAAAAAGATGAGTATGCCTGCCGTGTGAACCATGTGACTTTGTCACAGC
	CCAAGATAGTTAAGTGGGGTAAGTCTTACATTCTTTTGTAAGCTGCTGAA
	AGTTGTGTATGAGTAGTCATATCATAAAGCTGCTTTGATATAAAAAAGGT
	CTATGGCCATACTACCCTGAATGAGTCCCATCCCATCTGATATAAACAAT
	CTGCATATTGGGATTGTCAGGGAATGTTCTTAAAGATCAGA
	(SEQ ID NO: 204)

pARBI-600:	AAGATCTTAATCTTCTGGGTTTCCGTTTTCTCGAATGAAAAATGCAGGTC	2541
B2M_2_	CGAGCAGTTAACTGGCTGGGGCACCATTAGCAAGTCACTTAGCATCTCTG
Exogenous_5	GGGCCAGTCTGCAAAGCGAGGGGGCAGCCTTAATGTGCCTCCAGCCTGAA
	GTCCTAGAATGAGCGCCCGGTGTCCCAAGCTGGGGCGCGCACCCCAGATC
	GGAGGGCGCCGATGTACAGACAGCAAACTCACCCAGTCTAGTGCATGCCT
	TCTTAAACATCACGAGACTCTAAGAAAAGGAAACTGAAAACGGGAAAGTC
	CCTCTCTCTAACCTGGCACTGCGTCGCTGGCTTGGAGACAGGTGACGGTC
	CCTGCGGGCCTTGTCCTGATTGGCTGGGCACGCGTTTAATATAAGTGGAG
	GCGTCGCGCTGGCGGGCATTCCTGAAGCTGACAGCATTCGGGCCGAGATG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatTCTCGCTCCG
	TGGCCTTAGCTGTGCTCGCGCTACTCTCTCTTTCTGGCCTGGAGGCTATC
	CAGCGTGAGTCTCTCCTACCCTCCCGCTCTGGTCCTTCCTCTCCCGCTCT
	GCACCCTCTGTGGCCCTCGCTGTGCTCTCTCGCTCCGTGACTTCCCTTCT
	CCAAGTTCTCCTTGGTGGCCCGCCGTGGGGCTAGTCCAGGGCTGGATCTC
	GGGGAAGCGGCGGGGTGGCCTGGGAGTGGGGAAGGGGGTGCGCACCCGGG
	ACGCGCGCTACTTGCCCCTTTCGGCGGGGAGCAGGGGAGACCTTTGGCCT
	ACGGCGACGGGAGGGTCGGGACAAAGTTTAGGGCGTCGATAAGCGTCAGA
	GCGCCGAGGTTGGGGGAGGGTTTCTCTTCCGCTCTTTCGCGGGGCCTCTG
	GCTCCCCCAGCGCAGCTGGAGTGGGGGACGGGTAGGCTCG
	(SEQ ID NO: 205)

pARBI-601:	AGGAATGCTATGAGTGCTGAGAGGGCATCAGAAGTCCTTGAGAGCCTCCA	2541
B2M_3_	GAGAAAGGCTCTTAAAAATGCAGCGCAATCTCCAGTGACAGAAGATACTG
Exogenous_6	CTAGAAATCTGCTAGAAAAAAAACAAAAAAGGCATGTATAGAGGAATTAT
	GAGGGAAAGATACCAAGTCACGGTTTATTCTTCAAAATGGAGGTGGCTTG
	TTGGGAAGGTGGAAGCTCATTTGGCCAGAGTGGAAATGGAATTGGGAGAA
	ATCGATGACCAAATGTAAACACTTGGTGCCTGATATAGCTTGACACCAAG
	TTAGCCCCAAGTGAAATACCCTGGCAATATTAATGTGTCTTTTCCCGATA
	TTCCTCAGGTACTCCAAAGATTCAGGTTTACTCACGTCATCCAGCAGAGA
	ATGGAAAGTCAAATTTCCTGAATTGCTATGTGTCTGGGTTTCATCCATCC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGACATTGAA
	GTTGACTTACTGAAGAATGGAGAGAGAATTGAAAAAGTGGAGCATTCAGA
	CTTGTCTTTCAGCAAGGACTGGTCTTTCTATCTCTTGTACTACACTGAAT
	TCACCCCCACTGAAAAAGATGAGTATGCCTGCCGTGTGAACCATGTGACT
	TTGTCACAGCCCAAGATAGTTAAGTGGGGTAAGTCTTACATTCTTTTGTA
	AGCTGCTGAAAGTTGTGTATGAGTAGTCATATCATAAAGCTGCTTTGATA
	TAAAAAAGGTCTATGGCCATACTACCCTGAATGAGTCCCATCCCATCTGA
	TATAAACAATCTGCATATTGGGATTGTCAGGGAATGTTCTTAAAGATCAG
	ATTAGTGGCACCTGCTGAGATACTGATGCACAGCATGGTTTCTGAACCAG
	TAGTTTCCCTGCAGTTGAGCAGGGAGCAGCAGCAGCACTTG
	(SEQ ID NO: 206)

pARBI-602:	GATCTCACATTCTAGCGCCCAGACATGTCGGGAACGCCTTACGCCAACTT	2541
CAPNS1_1_	GGGGTCCCCACCAAGAGAACCCCCACCAGATCTGCACCCTCCCCTTCACG
Exogenous_7	CGTGCACCCAGTCCAGGCTCCCTCAAGCCCCACGGGTGCCTTTTAGACCT
	GAGGAGGTTGCAAACCTGATCCCCCATACCTGCCCCACCCATCCGCGGAC
	AACCCGCCCTCGCAAACTCAGACCCCCACCCGGAGGCTTCAGATTCCTCC
	CAGGTCCAGCTGCCGGAAATGCGTGTTTGAAGGGAGGGTGTGGGCTCAGG
	GGCGAAGCACCCACTGGTCCCCTTTTTTCCCCCCAGCAGTGAGTCGCAGC
	CATGTTCCTGGTTAACTCGTTCTTGAAGGGCGGCGGCGGCGGCGGCGGGG
	GAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatAGCGGGGCC
	GGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGG
	TGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCA
	GGTAAGGCGGAGACTATCAGAGGGGCGGGGCCTGGGAATGGGAGGAGCCT
	CAGTGAGGCGTGGTCTGGGAGGGGCGTGGTCTAAAAATAGAATAGGATTA
	ACCTGGAGGCTAACCTGGGTACATGAATTAGGCCGGGGAGGCCTGGTTTG
	AGAGTTCTGCTGTAAGGGGGTGGACCCCAGTGAGGCGGATATCAGTCATT
	GGGGGCGGTGCTTGATATGGGAGTAGTCTGATTGTGTGGGACCAGGACAA
	TGTGGTCCTGAGGGGACTGATGTGGAGTTTTGGCGGGTGGGGCTTATGGG
	TCTGGGCTCAGCCTGCATTGGCTAACCTGGAGATGAACGTT
	(SEQ ID NO: 207)

pARBI-603:	CGGGCATTTAGGAAGCGGGCCATGGAGTAGGGTCTTGGGCAGATGGCACC	2541
CAPNS1_2_	TGAGGAGGATAAGGCCTTGGGAAGCTGGGGCAGAGCCTCTATGAAGTGAG
Exogenous_8	CCCTCCAAGGGGCGGGGTCTTTTGATTCTACGTGGGATTTTTTAGGTTTA
	GGGTGGCCAAGATGACTGAAATCTGCCACTGGGTAGGTGTGCCTGGCAGG
	AGGGGAGCCTCCCAGGGGACCGGTCTCTGGGTTTCCTCGAGGGTGGGGTT
	GGCCTGAGGAAGGGAGAAGAGGGGCACGACCAGGGCAGTGTGGATTGGGA
	CAGATGAGGACAAGAACAAATGAAAGGCACAGCAACCAAGTAAGGAAGAT
	AACGGCTGGGGTCTGGAGCGTTGGGGCTGATGGTTCTGTAGTGCTGCCCG
	TTGGAGGCCCCGCCCCTGGCACTAACCCCTCCCCCTTATCTCTTCGCAGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACAT
	CGCCCACAGTCCCCGAGAAGTTGGGGGGAGGGGTCGGCAATTGAACGGGT
	GCCTAGAGAAGGTGGCGCGGGGTAAACTGGGAAAGTGATGTCGTGTACTG
	GCTCCGCCTTTTTCCCGAGGGTGGGGGAGAACCGTATATAAGTGCAGTAG
	TCGCCGTGAACGTTCTTTTTCGCAACGGGTTTGCCGCCAGAACACAGCTG
	AAGCTTCGAGGGGCTCGCATCTCTCCTTCACGCGCCCGCCGCCCTACCTG
	AGGCCGCCATCCACGCCGGTTGAGTCGCGTTCTGCCGCCTCCCGCCTGTG
	GTGCCTCCTGAACTGCGTCCGCCGTCTAGGTAAGTTTAAAGCTCAGGTCG
	AGACCGGGCCTTTGTCCGGCGCTCCCTTGGAGCCTACCTAGACTCAGCCG
	GCTCTCCACGCTTTGCCTGACCCTGCTTGCTCAACTCTACGTCTTTGTTT
	CGTTTTCTGTTCTGCGCCGTTACAGATCCAAGCTGTGACCGGCGCCTACT
	CTAGAGCTAGCGAATTgccgccaccATGGTGAGCAAGGGCGAGGAGCTGT
	TCACCGGGGTGGTGCCCATCCTGGTCGAGCTGGACGGCGACGTAAACGGC
	CACAAGTTCAGCGTGTCCGGCGAGGGCGAGGGCGATGCCACCTACGGCAA
	GCTGACCCTGAAGTTCATCTGCACCACCGGCAAGCTGCCCGTGCCCTGGC
	CCACCCTCGTGACCACCCTGACCTACGGCGTGCAGTGCTTCAGCCGCTAC
	CCCGACCACATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGG
	CTACGTCCAGGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGA
	CCCGCGCCGAGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAG
	CTGAAGGGCATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCT
	GGAGTACAACTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGA
	AGAACGGCATCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGC
	AGCGTGCAGCTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGG
	CCCCGTGCTGCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGA
	GCAAAGACCCCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTG
	ACCGCCGCCGGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtt
	tattgcagcttataatggttacaaataaagcaatagcatcacaaatttca
	caaataaagcatttttttcactgcattctagttgtggtttgtccaaactc
	atcaatgtatcttatGAGGCGGCTGCGCAGTACAACCCGGAGCCCCCGGT
	AAGCCCCCTCTGCAACCAGACCCCCTTCTCCTGCCAAGGCCTCTTCGAGG
	TCCCATCCCTGTTCCTGTAGAGAAGCCCCACCTTCCTCCCCTTCTTGTGA
	AATTCCTCTGCCAGTTCCTCCCATGCCGTGTCTGCAGCTTCGCCATGGGT
	CTTAGCCATGCCCCACATACGTGCACCCCATTCACTACCACCCCTCATTC
	TTTTCCTCATCAAGCTGCCCAGCCCACTCTGACTTCCCCACCCAGGGTAC
	CTGGGTTTGGGGAGCCGTCCTGGCCGGGTTCCCCTCCCCCTGCTCTGAGC
	TCTCCTCCCTTTGCAGCCCCCACGCACACATTACTCCAACATTGAGGCCA
	ACGAGAGTGAGGAGGTCCGGCAGTTCCGGAGACTCTTTGCCCAGCTGGCT
	GGAGATGTAAGTAAC
	(SEQ ID NO: 208)

pARBI-604:	GCTGATGGTTCTGTAGTGCTGCCCGTTGGAGGCCCCGCCCCTGGCACTAA	2541
CAPNS1_3_	CCCCTCCCCCTTATCTCTTCGCAGCGAGGCGGCTGCGCAGTACAACCCGG
Exogenous_9	AGCCCCCGGTAAGCCCCCTCTGCAACCAGACCCCCTTCTCCTGCCAAGGC
	CTCTTCGAGGTCCCATCCCTGTTCCTGTAGAGAAGCCCCACCTTCCTCCC
	CTTCTTGTGAAATTCCTCTGCCAGTTCCTCCCATGCCGTGTCTGCAGCTT
	CGCCATGGGTCTTAGCCATGCCCCACATACGTGCACCCCATTCACTACCA
	CCCCTCATTCTTTTCCTCATCAAGCTGCCCAGCCCACTCTGACTTCCCCA
	CCCAGGGTACCTGGGTTTGGGGAGCCGTCCTGGCCGGGTTCCCCTCCCCC
	TGCTCTGAGCTCTCCTCCCTTTGCAGCCCCCACGCACACATTACTCCAAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCC
	GCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGTCGCGTTCTGCCGCCT
	CCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGTCTAGGTAAGTTTAAA
	GCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCCCTTGGAGCCTACCTA
	GACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTGCTTGCTCAACTCTAC
	GTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAGATCCAAGCTGTGACC
	GGCGCCTACTCTAGAGCTAGCGAATTgccgccaccATGGTGAGCAAGGGC
	GAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGTCGAGCTGGACGGCGA
	CGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGGGCGAGGGCGATGCCA
	CCTACGGCAAGCTGACCCTGAAGTTCATCTGCACCACCGGCAAGCTGCCC
	GTGCCCTGGCCCACCCTCGTGACCACCCTGACCTACGGCGTGCAGTGCTT
	CAGCCGCTACCCCGACCACATGAAGCAGCACGACTTCTTCAAGTCCGCCA
	TGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTCTTCAAGGACGACGGC
	AACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGGCGACACCCTGGTGAA
	CCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGGACGGCAACATCCTGG
	GGCACAAGCTGGAGTACAACTACAACAGCCACAACGTCTATATCATGGCC
	GACAAGCAGAAGAACGGCATCAAGGTGAACTTCAAGATCCGCCACAACAT
	CGAGGACGGCAGCGTGCAGCTCGCCGACCACTACCAGCAGAACACCCCCA
	TCGGCGACGGCCCCGTGCTGCTGCCCGACAACCACTACCTGAGCACCCAG
	TCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGATCACATGGTCCTGCT
	GGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCATGGACGAGCTGTACA
	Aatgattgtttattgcagcttataatggttacaaataaagcaatagcatc
	acaaatttcacaaataaagcatttttttcactgcattctagttgtggttt
	gtccaaactcatcaatgtatcttatATTGAGGCCAACGAGAGTGAGGAGG
	TCCGGCAGTTCCGGAGACTCTTTGCCCAGCTGGCTGGAGATGTAAGTAAC
	CTGGGGTCCCTGGCCCCGTCCTAACCGTTCCATCCCTTCCCTTGTGGCTG
	CCCTTGCACACACACCCTTGACCATGACAATCCCAGTGTTCCCATTCTCC
	ATGACATTCTCAGACCCCTTTCAGTCACCCCTGACCTGCCCCTAACTTCC
	GCCCGCAGGACATGGAGGTCAGCGCCACAGAACTCATGAACATTCTCAAT
	AAGGTTGTGACACGACGTAAGTGACCGGGGTTAAGGAATAGGGTAGATTC
	AGAGGCAGAGGGGTCAGAGAGGATTTGACCTCTGGCCTCTGACTTTCAAC
	CTGTTACCCACAGACCCTGATCTGAAGACTGATGGTTTTGGCATTGACAC
	ATGTCGCAGCATGGTGGCCGTGATG
	(SEQ ID NO: 209)

pARBI-605:	ggagagttatagcagatggagacaaaaaagggaactgctggggatcaaac	2541
CBLB_1_	cttgtaaagtccttctaagtgatatatgaggactttgacttttattcaaa
Exogenous_10	gttagaaggctttgaacaaaagaattatttcatttgtgttttacaatggt
	cacaagtgccgtagcgagaataggctgTGTAGAGAAGAGATTTTGTGGTT
	TTCTTTTTTGTTCTCTGTATTCTCTTCCTGAAAAATCTGTTTTCTGCCTA
	ATCATATTTCTGTAAAGAACAATAGACTTGAACGTCTGCTGTTAAGTAAC
	AAAGGTTGACCTAAACCACATAAGGTCAGATTAACTTTTAAAATATCCAA
	GATAATGTTAAGTGTATTAAATATGGTTCAGTATGTAATCAAAATATTTG
	ATATTCTCTAGATACTAATCTCttttaatttttttattttttAGCCTTGG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGGCTCTATT
	TTGCGGAATTGGAATTTCTTAGCTGTGACACATCCAGGTTACATGGCATT
	TCTCACATATGATGAAGTTAAAGCACGACTACAGAAATATAGCACCAAAC
	CCGGAAGGTAAGACTTTTTAGCAGTAATATTATGTGATATATCCAAAGAT
	GAAAAATTCTCCATGGTTTGTTCCTAAGTAAGTCAGCAATACCCGCTGAT
	GGCATGCTTGGGAGGGGGCTAGAAAAGGTAAAAGACCAAAATGGTGCTTC
	TTAACATAATGTTTTAAATTGATACATTGTGCTTACTCTGAAACTTGGTA
	TTCATAAAGTGAAAGGGGATATGGTCTCCTTTCTGTTTTCATGATATCCG
	TGTTTATGTGCAAAATTGAATGTATATATTTGAATACTTGAATACTGTGC
	TAAAGAACAAATAAATAGAACAGTCTTATGTTCATTACTTT
	(SEQ ID NO: 210)

pARBI-606:	CATATTACTCATTTGTGCAATGAATAAAGGATTTCTATTATTATATGGAC	2541
CBLB_2_	CCATCATCTTATGACTGTTTTTAGAAAATGAGAATTAAATCTTGATTCAT
Exogenous_11	TATTAAATAACCTTGTATACACACATGAAGAGGTCATGACACATAAGACT
	TTGACCTAATACCTTTTTTCAGATATGTTTCTATAGCTATCTTGATAGCC
	TAGGACTGTTTGAGAGAAAATTAATTTAAATTTTTGTCATATTCTTAGCA
	AATGCAAAATAATTGAGTTAAACAGAACCCACTACATTTGTTCTGAAATA
	TGAACAATATTCTCAAATATTTGTCTGGTAGTACAAATACAATTATATTA
	ATTTTATTATTGAATTTTGCTGCTTCAAAGGGAGGTATTTCTTAAATGAT
	ACTTGATTCAATTATTTCCCTTTTTTTCCACCTTGCACAGAACTATCGTA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCAC
	ATGAAGCAGCACGACTTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCA
	GGAGCGCACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCG
	AGGTGAAGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGC
	ATCGACTTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAA
	CTACAACAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCA
	TCAAGGTGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAG
	CTCGCCGACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCT
	GCTGCCCGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACC
	CCAACGAGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCC
	GGGATCACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagc
	ttataatggttacaaataaagcaatagcatcacaaatttcacaaataaag
	catttttttcactgcattctagttgtggtttgtccaaactcatcaatgta
	tcttatCCATGGAAAGTATTCAGACAGTGCCTTCATGAGGTCCACCAGAT
	TAGCTCTGGCCTGGAAGCAATGGCTCTAAAATCAACAATTGATTTAACTT
	GCAATGATTACATTTCAGTTTTTGAATTTGATATTTTTACCAGGCTGTTT
	CAGGTAAGTTTATACTTGCTTAGTCTATCCATTCCCTtcttctctctccc
	tgtcttttctctctgtttctctctctctctgtctctctctcacacacaca
	cacaTAAACAAACATATGGAAAATAGTGTCATTCCTATTAGTCTGTAATT
	TTATTGGTATGTTTGGTCATTGTTAAAAGTTTAGAGTGAGCCATTTGGCT
	TAAGTTTGGAGTTATCAGATGCTGTGAGCCTGGTGGCTGCTTGTTAGCTT
	TGAGAGGATCCATCCAAAAGAGCTTTGTTTTAAACTCTCTACTTAGTTTC
	TTACTT
	(SEQ ID NO: 211)

pARBI-607:	TTAAACTTTAGAGGTTCAAAATAAGGATATGATATAGAAAAGATTGAATG	2541
CBLB_3_	GTAGGAGAACAGAATAGGATTTATTTATATTATGACAAACGTGACTATCA
Exogenous_12	GTTAATAAATTGGAGATAGTAAGTTAAGATCATTATTTATATTATGGAAA
	AATGAAGAAATAGGACATGGTTCTCTAACTTTTTAATTTTTCTGTGAAAT
	AAAATATTATGACTTATTTTATTTTTATCTTTGTTTTTAGGTAAGACTGT
	GCCAAAATCCCAAACTTCAGTTGAAAAATAGCCCACCATATATACTTGAT
	ATTTTGCCTGATACATATCAGCATTTACGACTTATATTGAGTAAATATGA
	TGACAACCAGAAACTTGCCCAACTCAGTGAGAATGAGTACTTTAAAATCT
	ACATTGATAGCCTTATGAAAAAGTCAAAACGGGCAATAAGACTCTTTAAA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGAAGGCAAG
	GAGAGAATGTATGAAGAACAGTCACAGGACAGGTAAGAAGAATATTTCAG
	ATGTTTTGGTGTAAAGGTCATTTATGTTGCTTTTTACTTAATAGTTAACC
	TAAACGTCACCATGTAATTGTTTTGGGGTAAATGTGAGTCGCTTTGTATA
	Tagtcatgtggtacttaacgatggggatactttacaagaaatgcattttt
	agacaatttcattgttgtgtggacatgatagagtgtacttacacagagct
	agatggtattacctaccgcacacctaggctgtatgatgtagcctattgct
	cctaggctgcaaatctatacagtatgttactgtactgaatactgtgggca
	gttgtaacacaatggtaagtatgtgtgtatctaaatatacctaaacatag
	aaaaggtatggtaaaaatactgtataaaaggccgggcgtgg
	(SEQ ID NO: 212)

pARBI-608:	AGATGAGAAAACCTATCCTTCCCAATTTTTTTGTGTGAGAATTAAAATGC	2541
CD2_1_	AGCAAGAAAACACACACTCATAAACACATCTGCTTTGGCAAAGGAGCACA
Exogenous_13_	TCAGAAGGGCTGGCTTGTGCGCGCTCTTGCTCTCTGTGTATGTGTATTAT
14_15	GTTTTATGTTACTGTAAAAGATGTAAAGAGAGGCACGTGGTTAAGCTCTC
	GGGGTGTGGACTCCACCAGTCTCACTTCAGTTCCTTTTGCATGAAGAGCT
	CAGAATCAAAAGAGGAAACCAACCCCTAAGATGAGCTTTCCATGTAAATT
	TGTAGCCAGCTTCCTTCTGATTTTCAATGTTTCTTCCAAAGGTAAGCATA
	AGAGTCAAAGAAGTCCCAACCCAGCTTTCCCTGAAAGTGACTCTCAGTAA
	CTCTTTTGCTTTTTATAGGTGCAGTCTCCAAAGAGATTACGAATGCCTTG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGAAACCTGG
	GGTGCCTTGGGTCAGGACATCAACTTGGACATTCCTAGTTTTCAAATGAG
	TGATGATATTGACGATATAAAATGGGAAAAAACTTCAGACAAGAAAAAGA
	TTGCACAATTCAGAAAAGAGAAAGAGACTTTCAAGGAAAAAGATACATAT
	AAGCTATTTAAAAATGGAACTCTGAAAATTAAGCATCTGAAGACCGATGA
	TCAGGATATCTACAAGGTATCAATATATGATACAAAAGGAAAAAATGTGT
	TGGAAAAAATATTTGATTTGAAGATTCAAGGTAAGTGTTCATTCCCTTAA
	TTGCTTTATTTCAGTGTGGGTGCTATTTGGCAAGTTGGAAAATAGCATTT
	CTAATATTCCCCAGCGCTGACCTCTGCCTCCAGGGGGGCTATACAGGAAA
	CCAGATGCATGTCTCCTGCCCCAGTGGAGACTGTGGTCCAA
	(SEQ ID NO: 213)

pARBI-609:	AGGATTGTTCTAGTTGATTGGTATGTGTGCACTCCTAGTTGTTAAATATT	2541
CD3_	TTCACTATCACACCTGGATATACTCAACAAATATTTGTTGAGCCAAATAC
E_1_	TCAACACCAGCCAAACACGTAGTATTTACTTTAGCTTAAGCGAATTATTT
Exogenous_16	AGCCCTGACAGAAGCCCTGGAATGTGGGTCTTTAAGTTCCTATTTTTGAG
	ATGGGAAAGCTGAGGCTCACGGAAGGAGGTGACCAGCTCAAGTCTCCTAC
	CGTCCATGCCAAATTAGAATTCCAGCCTGCCTCCTGACTTCAAGTCCAAA
	GTTCTTCCCACGCACTAAAGCTAGCTCTTCAGTGTCCTTTCTTAGGAGGT
	ACTTCCTCCCGCACCACTGACCGCCCCCTCTCTATTTCACCCCCAGCCCA
	TCCGGAAAGGCCAGCGGGACCTGTATTCTGGCCTGAATCAGAGACGCATC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatTGACCCTCTG
	GAGAACACTGCCTCCCGCTGGCCCAGGTCTCCTCTCCAGTCCCCCTGCGA
	CTCCCTGTTTCCTGGGCTAGTCTTGGACCCCACGAGAGAGAATCGTTCCT
	CAGCCTCATGGTGAACTCGCGCCCTCCAGCCTGATCCCCCGCTCCCTCCT
	CCCTGCCTTCTCTGCTGGTACCCAGTCCTAAAATATTGCTGCTTCCTCTT
	CCTTTGAAGCATCATCAGTAGTCACACCCTCACAGCTGGCCTGCCCTCTT
	GCCAGGATATTTATTTGTGCTATTCACTCCCTTCCCTTTGGATGTAACTT
	CTCCGTTCAGTTCCCTCCTTTTCTTGCATGTAAGTIGTCCCCCATCCCAA
	AGTATTCCATCTACTTTTCTATCGCCGTCCCCTTTTGCAGCCCTCTCTGG
	GGATGGACTGGGTAAATGTTGACAGAGGCCCTGCCCCGTT
	(SEQ ID NO: 214)

pARBI-610:	AATAATAAAATAATAACAATACTTAACATTTATTGAGTGCTTATTAAGTC	2541
CD3_E_2_	TCAAGCACTGTCTGTACCCAACACTTATCAAGGATTCTTTTTCATGTAAT
Exogenous_17_18	CCTCTCAACAACTATATGGGTTAAGTATCATTTTATTCCCATGAGTAAAG
	GGATGAGGAAACAGAGGGTTTGTGAGTTGAAAACACATTTCACGCTTCTC
	ACAGCTAGTGAGTAATAAAGCTGGGACTCAAACCCAGGGCTGTTTGACTC
	CAGTGCCTCTACCCACGGCCACCACTCTTTGCTTGTCAATGTTGTTCTAA
	ACATATTGAAGGGGGGGCTCTGACCGTGGCAAGCGTGTGAGTAGTAAGGG
	GAGAATGGCCTTCATGCACTCCCTCCTCACCTCCAGCGCCTTGTGTTTTC
	CTTGCTTAGTGATTTCCCCTCTCCCCACCCCACCCCCCACAGTGTGTGAG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatAACTGCATGG
	AGATGGATGTGATGTCGGTGGCCACAATTGTCATAGTGGACATCTGCATC
	ACTGGGGGCTTGCTGCTGCTGGTTTACTACTGGAGCAAGAATAGAAAGGC
	CAAGGCCAAGCCTGTGACACGAGGAGCGGGTGCTGGCGGCAGGCAAAGGG
	GTAAGGCTGTGGAGTCCAGTCAGAGGAGATTCCTGCCAAGGGGGACGACC
	AGCCTGGGCCAGGGTGGGTGGCAAGTCCACAGCTAGGTCAGAACAGCTTC
	TCTAGAGCTTCTATGCACAGCTTCTATTACTGTGATGACAAGATCTCAAC
	AGACGGTTTCAAATCTCACATCACTCCCCTCCTTCCCATCCTAGAAAAGT
	GCAAAAAAGTTTATGAAAGTGATGGGCTTCCTCACATACCTGTCAATGCC
	TGCAGTCATCCGATTCCGCCCCTAAGCTGTGGGAAGAGAG
	(SEQ ID NO: 215)

pARBI-611:	ACTGTGACCCATGAACCAGTAGGTATTGGCGTCACCTGGGATCCTGACGT	2541
CD3G_1_	TAGTCTCTGTCAATCCTTCTCTTTAGTTCATCTATTCTACCCAAAGTGAT
Exogenous_19_20	CTCATCATCTGGTATGCTGTTAGCAGTTTCTTACCTGTATAGTATCTTCC
	AAATAACATGCCCCAAAATCCCAAAGTTTTACCCCTACTAATTACAGCAA
	TGTCTCTTTTATTCTTCACCCCCTGACGCAGATATTGGCGTCACCCGAGA
	GCATGTTAGTAATGCAGAATCTCCCCTCCCCAGAACTACTAAATAGCACC
	TGAAATTTTAACAAGATCCCCATGTGATTCATGTGCACATCAAAGTTTGA
	GAAACACTACTCTAATGATCTCCTGGTATGCAGAAGCAGGGAGAATTTCA
	GAGGCAAGATCCTTAATAGAACCACGGCTTTTCTCATTTCAGGAAACCAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatTTGGTTAAGG
	TGTATGACTATCAAGAAGATGGTTCGGTACTTCTGACTTGTGATGCAGAA
	GCCAAAAATATCACATGGTTTAAAGATGGGAAGATGATCGGCTTCCTAAC
	TGAAGATaaaaaaaaaTGGAATCTGGGAAGTAATGCCAAGGACCCTCGAG
	GGATGTATCAGTGTAAAGGATCACAGAACAAGTCAAAACCACTCCAAGTG
	TATTACAGAAGTATGTAATCCCCTTTGGTCTGTTTGTTGTGAAATTAATC
	AGTATTTGCTGTTCTGGTGAGCTTTTTATCTGGGGTGAAAGTGGAAATAG
	ATCCTCAACAGTAATATTATCGCCTGTTCTCTTAATTTCAGCTTGCCTCT
	TTTAAAATACTGTAAGATACTTCCCTCACCCTATTGAAAAACTACAGCCA
	GTCCTGTAAAATTTTGTTTACCTTTGGGTGGGCTCCATGG
	(SEQ ID NO: 216)

pARBI-612:	TTCGAGACAAGCCTGGCCAACATGATGAAACTCTGTCTCTACTAAAAATA	2541
CD3G_3_	CAAAAAAAATTAACCAGGCGTGGAGGCGCGCGCCTGTAGTCCCAGCTACT
Exogenous_21	CAGGAGGCTGAGGCAGGAGGACCACTTGAACCCAGGAGGTCGAGGTTGCA
	GTGAGCTGCGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGAAAGAC
	TCCGTCTCAAAAAAAAAAAAGAGAGAGAGAGAAAAAGAAAAAAGACAGAG
	CCTCCATCTCCTTGTCCTCTTTCCATCCTCAGGACCATGAAGTACCCACT
	CCAAATTCTCACATATAAAAAACATTCAATAAACATGCATCAAATTAATT
	AATAGAGGATGGAAAAAATGACTTATGACTGTGCTGTCCTTTCCAGCCCC
	TCAAGGATCGAGAAGATGACCAGTACAGCCACCTTCAAGGAAACCAGTTG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatAGGAGGAAT
	TGAACTCAGGACTCAGAGTAGGTGGGTTCTTCAATGCCAATTCTAATAAA
	GGACCCTTGCATCAACTGCCCTCGCAATTGCTTCTAAGTCTAGCTCCCTT
	CCCTAAGCGGCTATAAGCATCAGACTCTGGGGATCAGGGATTGGGACGTG
	GTTTGGGGTACTCTTTTCTAAAAATTCTGGGGCCATACTGATTGTCTTGG
	CCTAGGTAAATATGAATTTTATGTATCTGTAAATCCTGTCAGAGCAGGGC
	CTCAAGCCATAGAGATGCTGAATATTAATCTTAACCTACATTTGAATTTC
	TCATTATCTACACTATTAACATTTTGGGCTAATTAATTATTTGTGATGAG
	GGGCTAGCCTGTGCATTGTAGGAGTTATGGAAGCATCCCTGGCCTCTCTC
	CACCAGATGCTGGTAGATTGTCCAGTGTGACAATCAAAAAT
	(SEQ ID NO: 217)

pARBI-613:	GACCTCAGGTGATCTGCCCGCCTCAGCTTCCCAAAGTGCTGGGATTACAG	2541
CD5_1_	GCATGAGCCACCACACCTGGCCTAAAATTAATTTTTAAAGATCTCTTAAA
Exogenous_22	AAGCAGACACCAGCCCCAATCTCAGACCCCTTGAGACAGAATTTCCAGGA
	CAGGGGCCATCCTGCTGGACAGTGGGTGCCGAGAACACCTTGCCCATTTA
	TCTGAGCTCCCTTCTGACTCTGAAATCTGGAGCCCCACCCTCCTGGGTCT
	AGCTTCGGGGCTGCCTGGGTCAGGGTCCTCTGGGAAGCCCCTGCAGTGCC
	CCAGAAGGGACGAAGCTCACAAGGGGCAAGGCAGGCAGCCCACGGGGCAG
	GAGGGAGCTCAACTGGGCGTCCTAGGGAGAGGGCAGTGAGGGGTGCCAGT
	GGGGAACCCCTCCCAGCCTGACCCCCACCACACCTTTCTGACCCCCAGAT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTTCCAGGCA
	AGGCTCACCCGTTCCAACTCGAAGTGCCAGGGCCAGCTGGAGGTCTACCT
	CAAGGACGGATGGCACATGGTTTGCAGCCAGAGCTGGGGCCGGAGCTCCA
	AGCAGTGGGAGGACCCCAGTCAAGCGTCAAAAGTCTGCCAGCGGCTGAAC
	TGTGGGGTGCCCTTAAGCCTTGGCCCCTTCCTTGTCACCTACACACCTCA
	GAGCTCAATCATCTGCTACGGACAACTGGGCTCCTTCTCCAACTGCAGCC
	ACAGCAGAAATGACATGTGTCACTCTCTGGGCCTGACCTGCTTAGGTGGG
	TAACTAGCCAGCCACACGGGCACCCTGGGCCTGGGCGCCAGCCCCGAGGA
	GACTGCCCGAGGCCTGTGATCTAGGGTCTGAGCAGGCTGGTGGAAGGGGT
	GGGGGGACCCCAGTTTATAACCACTCCCCAAGACACATACC
	(SEQ ID NO: 218)

pARBI-614:	GGACAGGGGCCATCCTGCTGGACAGTGGGTGCCGAGAACACCTTGCCCAT	2541
CD5_2_	TTATCTGAGCTCCCTTCTGACTCTGAAATCTGGAGCCCCACCCTCCTGGG
Exogenous_23	TCTAGCTTCGGGGCTGCCTGGGTCAGGGTCCTCTGGGAAGCCCCTGCAGT
	GCCCCAGAAGGGACGAAGCTCACAAGGGGCAAGGCAGGCAGCCCACGGGG
	CAGGAGGGAGCTCAACTGGGCGTCCTAGGGAGAGGGCAGTGAGGGGTGCC
	AGTGGGGAACCCCTCCCAGCCTGACCCCCACCACACCTTTCTGACCCCCA
	GATTTCCAGGCAAGGCTCACCCGTTCCAACTCGAAGTGCCAGGGCCAGCT
	GGAGGTCTACCTCAAGGACGGATGGCACATGGTTTGCAGCCAGAGCTGGG
	GCCGGAGCTCCAAGCAGTGGGAGGACCCCAGTCAAGCGTCAAAAGTCTGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCAGCGGCTG
	AACTGTGGGGTGCCCTTAAGCCTTGGCCCCTTCCTTGTCACCTACACACC
	TCAGAGCTCAATCATCTGCTACGGACAACTGGGCTCCTTCTCCAACTGCA
	GCCACAGCAGAAATGACATGTGTCACTCTCTGGGCCTGACCTGCTTAGGT
	GGGTAACTAGCCAGCCACACGGGCACCCTGGGCCTGGGCGCCAGCCCCGA
	GGAGACTGCCCGAGGCCTGTGATCTAGGGTCTGAGCAGGCTGGTGGAAGG
	GGTGGGGGGACCCCAGTTTATAACCACTCCCCAAGACACATACCCAGGAG
	GGGGACTGGAAGGGGCCAGCACCCATCTGTAGGATGGCAATGGAGGACCT
	AGTTCTGCCAATCACTGACTTCATCGTCGCCTCTGAACCTCCATTCTCCC
	ATCTGTGAAGTGGGGTGGTACTTCCCGCCTCGCAGGAGGCT
	(SEQ ID NO: 219)

pARBI-615:	tgctgggattacaggcatgagccaccacacctggcctaaaattaattttt	2541
CD5_3_	aaagaTCTCTTAAAAAGCAGACACCAGCCCCAATCTCAGACCCCTTGAGA
Exogenous_24	CAGAATTTCCAGGACAGGGGCCATCCTGCTGGACAGTGGGTGCCGAGAAC
	ACCTTGCCCATTTATCTGAGCTCCCTTCTGACTCTGAAATCTGGAGCCCC
	ACCCTCCTGGGTCTAGCTTCGGGGCTGCCTGGGTCAGGGTCCTCTGGGAA
	GCCCCTGCAGTGCCCCAGAAGGGACGAAGCTCACAAGGGGCAAGGCAGGC
	AGCCCACGGGGCAGGAGGGAGCTCAACTGGGCGTCCTAGGGAGAGGGCAG
	TGAGGGGTGCCAGTGGGGAACCCCTCCCAGCCTGACCCCCACCACACCTT
	TCTGACCCCCAGATTTCCAGGCAAGGCTCACCCGTTCCAACTCGAAGTGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatCAGGGCCAGC
	TGGAGGTCTACCTCAAGGACGGATGGCACATGGTTTGCAGCCAGAGCTGG
	GGCCGGAGCTCCAAGCAGTGGGAGGACCCCAGTCAAGCGTCAAAAGTCTG
	CCAGCGGCTGAACTGTGGGGTGCCCTTAAGCCTTGGCCCCTTCCTTGTCA
	CCTACACACCTCAGAGCTCAATCATCTGCTACGGACAACTGGGCTCCTTC
	TCCAACTGCAGCCACAGCAGAAATGACATGTGTCACTCTCTGGGCCTGAC
	CTGCTTAGGTGGGTAACTAGCCAGCCACACGGGCACCCTGGGCCTGGGCG
	CCAGCCCCGAGGAGACTGCCCGAGGCCTGTGATCTAGGGTCTGAGCAGGC
	TGGTGGAAGGGGTGGGGGGACCCCAGTTTATAACCACTCCCCAAGACACA
	TACCCAGGAGGGGGACTGGAAGGGGCCAGCACCCATCTGT
	(SEQ ID NO: 220)

pARBI-616:	TGTCCAAAGTGTGTGTCACCTGCTCTGTGTTCACCCACTGGGTTCATCAG	2541
chr2_1_	AGGGGCACTTGAACAAAACAGGAATGTCACTGGAGAGGGGAACAAATGCT
Exogenous_106	GTCCCCAAGTCCTTCCCTGCCGTTTAGAGTAACGCAGCCCCTGTCCGCAC
	ATCCTCACCCCCATCTGCCCTCTGCTTGCCAGAATTATCAGAATCTCTCA
	ATTCTAATTTCAGCCATTCTCTGTGAAAATGAAAAGTTAGTGGCAGGCAA
	TGGACACCCTATTGAAATAGAAATTGTTCTTCATATGTCAGAAAAGTCCC
	AGAGTAATCTGGGAGTAATCTGAGCAAACTGATTCAAAGGATTATTACAA
	TTTCTTAGTCTTCTACTGCTGCAAAAGTGGCACTCTTTGATTCTCATGTT
	TGAGGTTCTAATTACTACCTCATGCAGGACTTACAAGAGATCAGCCATGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTGCTTACAT
	TGTGTGTAGTGAATCAATGTTATTCTGAAGGGCCTCCTGGAAGCAGTAGG
	GATTGGAGAATGTATGTCTTTTAACATGATCATTCCCATCCTATGGGGGT
	TGGGCACTCTTAACTCATGTTGCAGATGAGTAAACTGAGGCTTTTGAGAG
	TTTGAGGGTGCACAGCTTGAGGCAGAGGTGGAATTCCCAGCTTCATCCAA
	GAAATCACGAATCTCCAATGGCTTGCACACATCCAGGTTTGCTGGATCCT
	ATTTGTCAAGACCACATGCAGATTAGGAGCCTTCAAACAAATTATTTCCA
	AGGGAGGGCATCTTTCTCTGTAACCCCTACCCTGGCAATTCTCCATGGCC
	TCAGGGAGTCCAGCCGGAAGCTCTGCAATGAGTCCTGGGGAACTCTCATC
	TGGAAAAAGGCGCTCATGACAGGTGGTGCCAACCTTCCACG
	(SEQ ID NO: 221)

pARBI-617:	CTACAAGCATGCATCACCAGGCCTGGCTAATTTTTCTATTTTTTGTAGGG	2541
chr2_2_	ACAGGGTTTTGCTGTGTTGCCCAGGCTGGTCTCAATTTCCTGGACACAAG
Exogenous_107	CAATCTGCCTGCCTCAGCCTCATAATGTTTTTTTTTAATGTTAAACCCCT
	TCTTGTGTTGAGAGGCCTGGCTTGTGTGTTTGAGCGCAGCTGCCTACCTT
	TGCAGCTGTAAATGTCAGGGCTCCAGGAGGGCTGGCTGGGTCTCCCCTCC
	TCCCCTGTTGGGTGGGTGGGGCCCTGAGCTTATCCAGGCATCCCTAGGTG
	GATGGATGGGTGGATGGGTAGGCCCTGGCCTTCAGGGAATGCACTGTGTG
	TGGTCTTCCAGCCCCAGCAAAGTCTCAGGGGGCCCGAGCGGGAAGTCGCC
	ATCCTCAGGGGGTCCGAGTGGGGAGTCACCATCCTCACGGTCAGCCGTGG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTTTCGAATT
	GAGCTCCCAGGGGCGGAGACTCCATTCCCCCGGGGAACAATCTGATAGCC
	AGAAATGAGAGCAGTGAGTGACTTGGACGCTGTGTGATTCAGGAGGGTCC
	CAGTCCCTCAGAGTCGCCTGGACACCAGATTGTATTTACAAAACAGATGG
	ATGAGGAAATGGAGATTGGGTCTTCAAAAGAATTAACCTCAGATTTTATT
	TATTTATTTTAAAAATTTTAATTTTTCCCAAGGACCCTTTCCAAGTCAAG
	AATTGTTTTAAAAAGAAGCCTGGTGAAGGCAAATGCTGTCTGTGGCCGAA
	GGCACCGTGAGGAGCTGAGGCTGACTTATGTTTCTCCTCTGGGCTATGTG
	CGCCTCTAAGGAGTTCACACACTTTAACCCCCTTAGGAACCCTACATGAT
	CATCCTCGTTTCTTAAAGAGGAAGCAGAGCCAGCAAACAAG
	(SEQ ID NO: 222)

pARBI-618:	TCTTGATGGATACCCATCCTTCTCTGCTGTTCTCTCTTTCCTCCATCCTC	2541
chr2_3_	AAGCACAGGGAGCTTTTGGCGAGGTTAGCTAACTTCGGGGCAGCTGTGAA
Exogenous_108	TTAGATACTGGCTGTAAGTTACCTCCAACATCCAGAGCATTTAAACGCTC
	GGCTGTCAATGATTGTCATTTTCATTGTTTACATATAGTCACATCCTCAG
	TTTGTGGGGTGGATGCATTTGATTCAATTCAGATATGCCTTTCAAGCTGG
	CCCTGCTGAGCTGGGCCTGAAAGGCACATGGCTCATCTCATCTGCATGTG
	ACAGTCTCTTTGAAGTCCCCAGAAGTGCCTGCTCAGAGTCATGCTCGGGA
	GGGAAGAGGTAAGGCACAGAATGAGTACAGACTGCCACCCAGCCGCAGGA
	AAGGTGACTGCACACCAGAGGTTCCTGGTAAGGAGGTGACTCACCCGCGA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCTGTCTCAC
	CTGTCCAAAGTGTGTGTCACCTGCTCTGTGTTCACCCACTGGGTTCATCA
	GAGGGGCACTTGAACAAAACAGGAATGTCACTGGAGAGGGGAACAAATGC
	TGTCCCCAAGTCCTTCCCTGCCGTTTAGAGTAACGCAGCCCCTGTCCGCA
	CATCCTCACCCCCATCTGCCCTCTGCTTGCCAGAATTATCAGAATCTCTC
	AATTCTAATTTCAGCCATTCTCTGTGAAAATGAAAAGTTAGTGGCAGGCA
	ATGGACACCCTATTGAAATAGAAATTGTTCTTCATATGTCAGAAAAGTCC
	CAGAGTAATCTGGGAGTAATCTGAGCAAACTGATTCAAAGGATTATTACA
	ATTTCTTAGTCTTCTACTGCTGCAAAAGTGGCACTCTTTGATTCTCATGT
	TTGAGGTTCTAATTACTACCTCATGCAGGACTTACAAGAGA
	(SEQ ID NO: 223)

pARBI-619:	TGAGCAAATAGTTCTATCCTTTTTGACACATTTTCCACAGTTTGTATAAT	2541
chr3_1_	TTATTCATAGAATCCTTCTTAGACTACTAATAAATTCCTATGGGACATAG
Exogenous_112	TCCTTTTATATGCGGAGGAATCCACCACCATGAAATGTTCACAAGAAATG
	ACTTTTAAAATTTTATTTGTGGCCATGCTGATTATGAATTTCTGAATTAT
	GTCTGGGCTGCTCTTTTTCTCGGAATATGCAAAGTGGGATACTGGCATCT
	CTGTATCTGGAGAGTTACAGCTTCTGAGTTAAAAGATGAATGGGAAGTAG
	CAGGAGAGGGAGAGATCAGAAATCTCCACTCCCTGAAACACAGACACTTC
	ACATACCCAGGAGGTAAATTCCTGGCATGAATTGTAACAAGTATACACAG
	GCATTTGTACATTGTTTGCTTATGTGCTAGATGACATGGCAGTCTATGAA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCAGGGGCCC
	CACATCTGCAGGCAGGACATTCAGCCCTGTATCTTGCCACTACCATGAAA
	TCTGAGGTTCTTTCATTTTTGTTTTTCTATTCTGATGAGATTGAGGTACA
	CTGACTCACTGGTAAAGAAGACAATTTATTTGTGAACTTGTAGTCACTCC
	ATTTGACGGCCTCCCTCTACTCACTGAGGCACAGCACGTGTGGAACAGGA
	AAAAGGCCTCTGGAGAGCTTGTGTTCCACTGGTTTCTTTGACTTTTGCCA
	ACCAACTTTGCAAATGTTCTCAAAAGGCATTCATTACCTCTGCAGGTGTG
	AAATAACTCTGCAGTTCAAGGGTTTGTGAAATCACGTGAAACAGCTGAAA
	GCTGTTCTGGCAAAGCGACCAGAGTCAGAGTTAGCTGTCACCAAGCCACA
	TCCTGGCTTAAACGATGTTATTTATATCTAACTGCACTCGA
	(SEQ ID NO: 224)

pARBI-620:	AGATGCCCATTGTACCACCTACCATTGCTTGACCCCCGCCCATGAGCTGT	2541
chr3_2_	TCCTTCATACTCATAACTAAAATGCCAAATGTGTGACTTGAGTAATTAAC
Exogenous_113	TAGAGACCTCCAGAAGGCTTTCCTTCTTATTCTGGGTACATTGATATTTA
	CTTTAGTATTTGTTTTGCCTTTAAAGTCATGTTCCCTTTTGATTCTTTAA
	TATCATATCCAAAACGAAGTCCTTTTAACCTATAACAATGCAAATCAAAA
	GTGCTGTCTTTCAGCTACCTCAAGGATTTAGCAAGCGTTCCTGGAAATCT
	AACCAACCTTTTAAAAAGTATTTCTATGGGAATGTATTTCTGAGCCCTAA
	ATTATGGATTTTGAAACTAAAATAGAAGAATACTGTAAGTGCAAAACTTC
	CAGTAGATAACAGAATTTGCAAAATCTCTAATCTCTTGTATGTGCCCCAA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatGTAGTACTCT
	CTATAGGCCATTGGAACAGAACATCTGGCTTAAAATAATCTCAGCACCAA
	AAACGGTCTAACTATGGTCTCCACAACATAACCCGATGGTTCTCATATTT
	TAGATGCTTGATGCACAAGTTGAACTGGCTAACAATTCAGACTTCAGGAC
	TTGACTCCCCTGGGAATCTGCAGTTGTTTCCCTCCCCTTGAGTGAGACTG
	ACTGTTGGGAGTAGAATAACCGCATGCTCTGGGTCAGAATGCCTGGCCCT
	TCAGAGTAACGGCAGCCATGATCGCTGAGCTCCTACTGTGAGGCACATAC
	TTCGCCACACTAACACATGGAATCCTTGCAAGCTCCTTACATAATCAGTA
	TTTTATGCACTTTGCAAATGAGAATACTAAGGCTCAGAAGAGGCAAGCTC
	CTCTCCCACTGTTAAACAGCTAGTGATGAACAGAGCTGGG
	(SEQ ID NO: 225)

pARBI-621:	ACTCCCCTGGGAATCTGCAGTTGTTTCCCTCCCCTTGAGTGAGACTGACT	2541
chr3_3_	GTTGGGAGTAGAATAACCGCATGCTCTGGGTCAGAATGCCTGGCCCTTCA
Exogenous_114	GAGTAACGGCAGCCATGATCGCTGAGCTCCTACTGTGAGGCACATACTTC
	GCCACACTAACACATGGAATCCTTGCAAGCTCCTTACATAATCAGTATTT
	TATGCACTTTGCAAATGAGAATACTAAGGCTCAGAAGAGGCAAGCTCCTC
	TCCCACTGTTAAACAGCTAGTGATGAACAGAGCTGGGACCTAAACTTGTC
	TGATTTCCCACACTGCTGCTCCATCAGATTGTTTGCCAGGTTAAGGATTC
	ATGCCAGGACCTTAAATCCCTCTGAATCGACAGAGCTAACCTAAAGGGCA
	CCTTGATTTCAGGTTTTGTTCCCAAACCTATGACTGTGGCCTGGCCACGT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatAATGAAGAC
	CCGGTTGGTTCTAGCTTCACAATGAGCTCATTGGCATTGTCCCCACAACC
	ACCACCCCCTCTCCACCTCTGATCATCCACTATCATTTCTATATGGCCTT
	TGCCAGGCTTGTCCTCATATCAAAGCTTCTGCCCTCTATGTTTAAATGCA
	TAAGCTTGACAAATGTTTTCATTTGAGAAGGCAAGCTGCCTCCCCGTGCT
	TGGTCTAATGTGAGCTTGGTAGAGTGACACTGCTGGATTCAGTTTTAGTC
	ATCAACACTTCCAGCTGATGCTGATCTGAGTAATTGTCCTATTTAGACTC
	TGACAGGTGAAAGTCATAGATTCAGGAAACGGAGACTCCCCTCACCCTGC
	TATGAAGGGGAGTTTGAGAGGGTTGGGCAGCTCTTCCCGGCAGTGGCAGG
	CAGTGTGGGGACACACGTATGGATAAATTGTTAATGCTCTT
	(SEQ ID NO: 226)

pARBI-622:	CTGCAGGTGGCAGACTTACTCATTCTCATGCTTCAGCTCCAGGGGTTCCC	2541
chr3:	CTGTATGAGTCTTCTCTGCCCGCTCCCACACCCCAGGTAGCATTGCCCCT
1865_	GCTTGCTTTGTGCCCTCACTGTCTCCACATATATACACATCTCTTACAAT
Exogenous_109	AATATTAAATACCAGCCAACATTTATATAGTACTTCTTATGTACCAAGTA
	CTGTTGTCTATCTATCTATCATCTATCTATCTATCTATGTACACACACAC
	TCATATTATCTTCACAATGCTATGAAATAGGTATTATTGCTGTCCATTTT
	ACAGATGGGGAAACCAATCTATAATTGGTTTAGTGAGATTTACTGAGCAT
	ATCTACAGGTATTTGTCCTTGGTTATAGGAAACCAATCTGTCACTGGTTT
	CCCCTTCTGTAAAATAAGTTAAATAATTTGCTTAAGCTCACTCAGATAGT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatGTGTGGTTGA
	GTCATAATCTGAGCTACTCTCTGGCCCAAACTGCTTATTGTAACCACCAC
	ATCATATGGCCACTTCAGCACCAGTCACACCTCATTTTACTTGTTGATGT
	CTCAGTTTTCCCCTCTATTCTGCGGGCTACTTGAGAAGACTTCTGTCTTC
	TTCCTCTAGGTATCTCTGTGCTTGACTCAGTATCGAGACCATAGGTGTGT
	GGGTGGGGTTAATCCACACTTGCTGAACACATGTGTCCGTGCCCAATGTC
	CCTGTGCATAGTGGCTACTTCCCATGGTTCACACGCATCTTCATGGCTCT
	TGTTTCTTCCATTCACCCATCCCATGTCCCTGGCCCTGTTCTCAGTGCTG
	AGGATGGAACCTCATTGCTGCTGCTTCCAGCCCTGGCCCTGCCCCTGTTT
	GGGGCTCAGTGCTTCATCCCGTGGAGCTCAAGGGGTGCTG
	(SEQ ID NO: 227)

pARBI-623:	CTTCTCATCCTCACACCCATTCATTTCTTAGTTTCCCATACTCTGACTTC	2541
chr3:	TACTACCCCAAGTTCATAAAGACCTCATGAACACAACCTGGAGAACGCCC
1865_	TCAGCCTCATCTCACCTCCCTGCAACACATGGCTCACTTGTCTGCTTCTT
Exogenous_110	CCTTCTTAGAGTCCTCTCTCTGGTTGACCTGTCAAAGATGGGATTCTCCT
	GTTAACGACCCTGACTCCTTTGTCTCCTTCTACAAAGATAATGCACTGAC
	TTTCCAAATGTACTAACTAGTATGATCATCACTGTCTACTGTTGCATCGA
	ACCACTACTAACCTCAATAGGGAAGGCACCAGGTTCAAGAGGCCAAAGAA
	GAGACCCAGAGCCAGCAAATGAGACATGGGGTTTTATGAGGGGCTCACAT
	AGAGGGGAGAGAGTCCAGTGGCAGTGGGCTGGGCAGGAGAACCACCTTAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatACGTGGTCC
	AGTGGTGGGAGGCTGGAAAAGAGATCTGTCTTGCCTACAGTTCAGTGGTG
	GCGGGTTGGGCAGGAAAACCACAACTGCCTGCAAACATCATGCAGTTTAC
	ATAACATTGTCACTTAGCAGCCTCCCCTAACGACCTCCACCTGGCAATCT
	TCATTTAACCCAAAACTCAAGGCCTCAATCCCCTGTATGGACCATGTTTC
	ATGGGACAGGCCAGGGGCTCAGAAGTTTATCATAGATAAGGAATGAATCT
	CCGGGTTGGCCACTCCTGGATTCCCTAGCTTGGAACACACATTCAAGTGT
	ATCTGCCATTCTGAGTGTATTCTTCAATTATTGCTGTCAGGTGTGTTGAC
	CCTCTATCTACATAAGTATTTCTCAAACCAGGGCCCTACGATCAGCATCA
	GCATCACCTGGGGTATATGTGAAAAATGCAGCTCCTGGACC
	(SEQ ID NO: 228)

pARBI-624:	GGGCCAAGCAAGCTCTGAGACAAGCTGTCTCACCTCCTCATCTCCTGAGC	2541
chr3:	ACAACTCACCCACAGCTCTGCCCTCGCCTCCACCTACATCATGCCTTCCT
1865_	GCATGCCAACTTCCCTCTGAGGTTCCCTTCACCCACTTACAACCACAGCC
Exogenous_111	TCCTTCCGGACCTCCCCTACACGATGAACAGTCTGCCAGTTAATATACAT
	CAAGCTGCCACCATGAAACAGCTCGGAAAGCCCCATTTGTTCTCAATAGC
	ATTCCAGCTAGAAAGACCATCCACCACCCATGGCCACTGAAGAAGGTCCT
	CCCCTGAGTGCCAGGCAGTGGGGCTCCTAACTCTGGGCCCCAATTAGCTT
	AGCTTGGGGGAGCAAAGGACAGGAGCACTGTTCACCCAGTTGGACTAACA
	GCTCCACACTGTGCCTAATAGGAACCTCCTTCTCACAGGTGGCACCTTTG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTGAATCAGG
	GTCTGTCCTGAGCCACCCTCCCTTGGAGAGATCTGAGCACTGAGAACCAC
	AGAGCCTGGGACACCAGCACAGGGTTTGAAAAACTCCACTCCCAGTCAGC
	TGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGT
	GGATCACAAGGTCAGGAGTTCGAGACAGCTTGACCAGCATGGTAAAACCC
	CATCTCTACTAAAAGTACAAAAATTAGCCAGGCATGGTGTTGGGCACCTA
	TAATCCCAGCTACTCGGGAGGCTGAGGCAGGGGAATTGTTTGAACCTGGG
	AGCTGGAGGTTGCAGTGAGCCGAGATCGCACCACTGCACTCCAGCCTGGG
	GGCTGAGCGAGATTCTGTCTCAAAAAAATGGGAAAAACATCATTCCCATG
	TGTGTCCTGGTTGCTTGTCTCTTTCAAAGTACTGCATACT
	(SEQ ID NO: 229)

pARBI-625:	CCACATCATGGACCAGAAGCCACTTGGTCTGGTTGTGAGGATGACGGAAC	2541
chr8_1_	CTTGCCCGAGGAAATGGGCAATGAACAGGAGCCTGTTTGTTTCTCCTTCC
Exogenous_115	AGCTCCTGACCTGTCTAGCTCCTGACCCTCTCAGTGTCATTCTTGCTCAC
	CCCTGGCCCTGCTCCCTGGATATGCAGACAGGATGGGCTTCTTCCCTTTA
	GACCTTCACTTTGCTCTTTTGGACTCCTCTTCTGGCCTTGCCTTCCCCTG
	GTGTCATCTGCTGGCTCCCTGCCTGATACTGCCACACTGGTCATGCTGGC
	CTCCTGGCCTTTGGTGACACCGCATCAGCAGGCTCCTGCTTCCCTGTCAA
	GGGATACAAGCCAGCACCGGTCTTTCGCCACAAGGTATGTGTGTAAAGAT
	TGCTTCCTGTACTTGGTGTCCACAGGATTTTAAAGAACTCCTGGCCCACT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCGGAACTCT
	ACGCTTGAAACAGAAACATCTTCTCAAAACACCTCTGGTATTGGCCCATT
	TCTCTATTACTGTTTCTTGTGGTTTCATACTGAGGTTTTTGGTGCATTGC
	AATTGCCCTGGAGTTTATTTTTAGTAATAAAGACAGAGTTCAATTAATGT
	CAAAACATGAGGGTAATTGCAGAGGAAGGATTAGTAAGTCTAGGGGAAAA
	TGTGCCCAACTTTTTTTCTTCTGATAACATCTTTCACTGATCATACACCG
	TCACACCCACAGACACGGAGCTTCCTCCGTGATGTCTGCAATGCACTAGG
	CCCAGTCGGGGAGCAGTGGCTGCGCCACCACCTGAAAACGAAAGCATTTC
	TGAGTCTCTTTCAGTCCAGCTCATCTAGCAGCCAGCCACACAGGTGACCA
	CCCACCGTAGCTGTCACTATGGGTGATGATTATCATTATGG
	(SEQ ID NO: 230)

pARBI-626:	AGGATCTTTCTCTCTACAGTGCCTCTTGTGGGACGGGTTCTGCTGATGGG	2541
chr8_2_	GGCTGTGTTTGGGATCTCGCCTGGAAACACGATCTCTCCAACTTTCCCTG
Exogenous_116	GGAGCAGAGCCTTGGGTCTCACTGAACCCACCTCCCCAGCACCTTGTGTG
	GTGACTGGCAGGAGGTAGCCATTCCCTCCTGTCCTCTCTGCCCTTGTCCA
	CTTTCCTGTTATGAGTCAGTTGCTGAGATAGGCTATGAGGAGTTAACAGA
	GTGGATAAAAAAGAGCTTTGTCCTTCTTTAAAGCCTTCAAAATATACAGA
	TGTATTAGTCAGGGCTTTCCAGAGAAACAGGACCAATAGAACATGAAGAT
	AGATGCGTATCCATGTCTATATCAATATCTACCTTGATATTTATATCTAT
	ATCTAGGAGATTTATTTATTATAAGGTATTGGCTCATGCAATTATGGACC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCAGAGGGGT
	CCTGTGATTTGCCACCTGCAGGCTGGAGACCTAGGAAACAGCTGTCGTGT
	CACAAAGGGCAGAGGGCTGGAGAACCTGTAGTGTAGATTCCAGTCCAGAT
	TCGAAGGCCTGAGGACCAGGAATGCCAAGGGCAGGAGAAGATCGATGTCC
	CAGAACAAGCAATCAGGCAGAGATGAAATTCAACCTTCCTGTGCCTTTCT
	GTTCTATTCAGGCCTTCAGTGGGTTGAATGAGGCCCAACCCACATTGAAG
	AGGACCATCTGCTTTACTCAGTCTCCTGGTTGAAGTGATAATCTCATCTG
	GACATACTCAGAAATGCTGTTTAACCAGCTCTCTGGAAATCCTGTGGCCC
	AGTCAAGTTGACACACAAAATTAACCATCACACTGCAGAGACACAGTCTA
	TCCCAATACCTGTATTTACTGGGTAACGTGCATCTCAGCTC
	(SEQ ID NO: 231)

pARBI-627:	TAATAATGACTCTGCTGGTAATTTGTGTCCTTCTGCTTGGAACTGTTTCC	2541
chr8_3_	TTTTTAGTTTGGTCACCCTCCCAGAGCTGGTTTCAATGGGGGCATACCCA
Exogenous_117	TTATGGGATGCAGGGCATCCTGCATCCTGAGGAATTTTTTTTCCTCCAAA
	AATGAAACCTTGAAATGAGGACATTGTCCTGTCCACGGACTGCACAACAA
	CACTGAGCCTCAAGGACTCATACTGGCATTTTTCTTCTTTTGCAGAGTGT
	GGGCACCCTGGCTTCAAGCTCACGAGAAACCAGGTCGGGATTTAAACAAT
	GTTGGGTTAAAGCAAAGTTTCATAAAGACAGAATCAAGAAAAAAAGAAAG
	AGAAACCAATCTAAGTGCCATCCTCCCTGAGTTGCATCTTACCTGAGTCT
	TCAGCCGCCGCCCCCTGCTGCTGTGGGAGGAAACGGGAAAGTGACTGGCC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatATGGGGACA
	GGGGTCGGGGGTGTGAGGGTTAGTGGTAGCAGGGAGGTAGCACTTCTGTG
	AAGCCGGAAAGGAGACCTGAACCTGGCTCTCTGCTTTGCTGCTTGCCAGC
	CCTCTGGCTGGGAAGAAGGCTCTTGGCTCTTGTGAGCCTCGGTTTCCTCT
	GCAGAGTGGCCTGTTCTGAGGACAGGCTGACATTGCTGTCCATCAGTCTT
	CCAGGACCCTGAGGATTTCAGCTCTACCCATGGGCACTGAACTGGAACAT
	TCACTGGTCATTTGCTTTCGTTTTTTTTTTTTGTTTGTTTGTTTTTTGAT
	ACAGAGTTTCACTCTTGTTGCCTAGGGTGGAGTACAATGGCGTGATCTCA
	GCTCACCACAAGCTCTGCCTCCCGGGGTCAAGCGATTCTCCCCAGTAGCT
	GAGATTACAGGCATGCGCCACCACGTCCGGCTAATTTTGTA
	(SEQ ID NO: 232)

pARBI-628:	AAGTCAACAACAGGCTCCAGAAAAAAATGGAAATATAAATGGTCCCCAAT	2541
chr9_1_	TTGGCATTTTGGAATTTGAGGCTTATATAGTATGAGCAAAATAAACTCCT
Exogenous_118	CCTGCTTCTATGAATTCTTTGCACTTTTTCTCTATAATTCCTTATCAAGC
	AATGGGTTTGTCTGTTAACCAAGACTATACATAAAATGTATTCCCGTAGT
	TCCTTTTATTACATTTTTTCTTTGTTGTTACTAGTGGAGAAGCTAACAAG
	AGCAGAATTTCCTGCCCAACCGTAGCAAATACAGAAAATCAAAAAGAGAA
	GCTTTGATACAGCCAGTGTAGATACAGCTAGGACGTCATGAATCAGAGCT
	CCCACACACGATGATAATGGAAACATCTTATCCATATCTGATTTGCTCAC
	ATATAGTTATTTAGACAACAAATTTTACATTCCTGGATAGGGAGCCTCCG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatATTTGATTTC
	AATCTCATAGTCCAGGTAGGTGTAAAATGACTGCCAAGCCAGCAGACATA
	AATCTGTATTATCTCATTTTCATCACAGTCTCTGCATTGGGAAAAAAATG
	TGAGTGAAAAGACATTTTCTCCCACCTTGTTAAGTACACAATTACATAGT
	TTAAAGAAGATAAGAATTTCAAATTGTTAGAATGATATCATTATTCAAAT
	GATTCCCTGAGAACTTCAAGTATTCCCCTTCCCCCAAATGTAGGCAGGGC
	AAAATAGAACCAGTAGGAATGAAAAATGTTAATTGTTTCAGGTTCTGTAA
	TTTTGGGTTTAATGACTCAGGCTATGTGCTACTGAGTAAAATACTCATCT
	GGAGAAAAAGACTGTTGCATGACATATTTCTGATTAAGGACAATTTAAAC
	TAATTCTAAGAAAACTCTTACATACTGCACATGCCATAAA
	(SEQ ID NO: 233)

pARBI-629:	GATTAGGTCTGGAATAAGATTGCACCATGACTAAAATGACTTCTTTAGCC	2541
chr9_2_	AATGACATTCCTGAAGATTGGATCAGAGTAAAGTTAAACTAACCTACTCA
Exogenous_119	AGGAAGACTTTCCTAAATCAGCCCCTTTGCTGTATAATTTAGTATGGAGA
	GCTGATTGTGGGTTTTTCTTGTTTCATTGTTTAATACATAGAGGTTTCAC
	ATTTCATTTTGAAACAGAAAGAGGGACTGGAAGAGATAAGTTAGTATGAG
	TGAGGAAAAGATTAGAAGGTAGAGATAGGATCGCAATGCTGTTATCACCT
	TTGCTTTATTGATAATCTCAGGAAGGACTAGACTGCTAAGAAAGAGGAGC
	CCAGATTGGAATAAAAGAGACGATGCCAGGATCAGCCTGTGAGAGGATGT
	CTCACTTAGTACACCTCAAGGATCATGTCAGCTGAGCATCTATACCCCGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCG
	AGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGGGC
	GAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACCAC
	CGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTACG
	GCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACTTC
	TTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTCTT
	CAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGGCG
	ACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGGAC
	GGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAACGT
	CTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAAGA
	TCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACCAG
	CAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCACTA
	CCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGATC
	ACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCATG
	GACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaata
	aagcaatagcatcacaaatttcacaaataaagcatttttttcactgcatt
	ctagttgtggtttgtccaaactcatcaatgtatcttatGTGATGAATATT
	GCATACAGACTCTGCCTTCAAGTCATCCCCCATTCGACAAGCATTTATTT
	AAGGTTCTTACATTCCAGGACTTGTACTAGATGCTAGAAACAAACAGATA
	AGGAAAACGTAGGAAAATGCTTCTCTCAGGAAGCAATATTGTATATGAGT
	GGTGAAGAGCTTCAAATCTGGGGCCAAACTGCTGGGTTTGAAATTTGGCT
	TGGCCACCTACTGGCTGTGAAATCTTGGGCAACTTTCTTAATCACTCTGT
	GCCTCAGTTTCTTCATCTGTAAAATGAAATAGCCATAGTACTTATTACAA
	ATAGGTAATAATTAGTGAGAATTAATTTGAGTCAATACATAAAAATGACT
	CAGAATAAAAGACCAGCTAAGAATATATACACACATACTTAGCTACTTAT
	AATCTAGTAGGAAAGATGGGTATGTTATCAGAGGACTT
	(SEQ ID NO:
	234)

pARBI-630:	CAGATAAAAAAAGCTGAAGCTCAGGGATATTGTCATTTACCCATGAGCTC	2541
chr9_3_	ACAGGCAGGAAGTGGTGAAACTATCATTAAACTACGGTTGGCCTTGTTCT
Exogenous_120	TTTGTGGTTTCATTTCACTAAGCCTCTGACACCCTGACCTCAACTTCCTT
	CTGTAGATATGTCACCTGGCCTCCTTCAGTCTAAGACACTACACACTGGC
	CACACACTTTGTCATCCTCATAGACTGACAACCTGCTCTCACATACCCTG
	CTTTCTTACTGTGTAGGCTCTCTTTTCTTGCTCAGAATGTCCTTCCCCAC
	TTCTTCATGTGCCAACTCCTAGTCATCCTACAAGAACCACATTCACTTTA
	AGTTTCTTTTGAAGCCTTTTCAGTGTCCCATACCCTGATCCCATTACCTC
	TTCTATGTATGCAGGGCTTGCTTCATGCTTGTGTAACCCAAGGGCCCTGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatATTTGATTTA
	ACACATTTTAAAATTCTTAACAATTTATGAAAAAGGAAACCCATATGTTC
	ATTCTGCCCTGGACCCTGCAAATTATGCAGCCAATCCTGTGTGTGTTTTT
	TCATGTTGCGTAGACTCTATTACAGTCAGTAACATATTGAGAAAGAGTGT
	GTGTCTCCTCTGATAGTCTATGAGCTCCTTGAAGCAAGAGGCTTGTCTTA
	GTCATTGCTGTATCCTCACACCAGACTCTACGGGATGCTCAGGATTCACC
	TGTTGATCTGTGAGGAAGCCCAAGGCTCAGTTAATGCCCCCCACCCTCCT
	TCCATAACAGTCTCCTGATTAGGAAACAGTGCTTGACCTCTAGACAATCT
	GAGTATCCACTCCAGGAAGTGGAACATTGCCTTCCCAATGTTGAAACTGT
	TAGCACTCAATCATGTTTCAGGAACATATAGAAGGTATGT
	(SEQ ID NO: 235)

pARBI-631:	TGGACCTTATGCAGGGTAATAAAAACCAACACGTGGGGCCTGTGCTGTAA	2541
chr10_1_	GGTGGCAGAGGGCGATGACTCACCCCACTCATGCAGGTTGAGTCATTTCA
Exogenous_90	AGGCAGAGTTGTGCCAGTTCAGTACCCAGTAATATTTTCCAGTCGACGAG
	TATCAGTGAACAGGAGATAACCAGTCATTTCTAGATTCTGCTCAGAGTCC
	CAGCTTAGAGGCTCCACCAGCTCAAAGAGACGGGATGGCAAAACAGCCAC
	CTTAATTTCCAGATCATCTGCCAGCTCATCTGCCAGCTGACACACAGCCC
	ATGGCTCCACTATTGCCAGTGCTGTAGCTGCACCAGACCAATCTGGTTCA
	ACTTTTATGTAACAAAGTTGTGATTTGTTTTTCAGTTGCCCGGGACTCCC
	AGGTTGAAGATCATGAGCATGCCCTGATGAGCCAAGGCATGCAACCACAG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGGGAACCTA
	AGTGCTTGGACTGAGGAGTGGGGACTGAAATAAGAAGCGGACACTGCAGG
	GCAGGATCAGGATCCAATCAGATCGAGCCCTGGCATCACCTCATGGCAGG
	ATCTAGTCAGATCGTGGCTTTTGACATCACTTCATTGTGAAATCCAATCA
	GATCACACCTTATTACCCTATCCTTATAAAACCGGACCTAGCCCCCAGCT
	CGAGGAGGCACTGCTTTGGGAGTTATCCCAGGTGTTCTTGTTACTAGTTG
	CAAGGAATAAAATCCTCTTGCTAAATCCTCCTTGGTTGTGCAGATGTTGG
	CATGGATGTGGAGAGAAGGGAACACTTACGCTTTGTTGGTGAGGATGTAA
	ATTAGCTCAACTCTGTGATAAACAGTATGGAGAGTTTTCAAAGAACTAAA
	AATAGAACTTCTACTCAACCCAGCAATCCTATGAGTGCATG
	(SEQ ID NO: 236)

pARBI-632:	ACATCTAATCCCACACCATGACTAATAAACATGGCATGCTGCAATGGGCA	2541
chr10_2_	TTAATTTATGGGTAACAGAAGCAGATCCAAGCCTTTTAGCTAATTAAATA
Exogenous_88	AAAATGCACCATACAGCAACCATCCTGCCTGCTTGGGTGTAAAATAGAGA
	GGAGAAAGATGGCATGCTGGTCATTGAGAGATAATTACCTGCAATTTCAG
	AGCTGGAATCTAGTGACAACATAAGAAAAATAATAACCTCTCTGGCTGTT
	AGGATTCTCAGTTCTAGCTGCGAGCAAGGAGCAAAGGCACCCACAGACTT
	GCCAAACCTATGTCAGGAATGACGAATAGAAGGCAGAAATCCACATCCCC
	AGGTGGTAAAATTGTTATCCACCTTCGTCACCTCTTTCCTAATGGAGGAA
	GTGAGGACAGGCAGCCTTGGAGTCCTACTTGAATGAGGCCTGGACCTTAT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGCAGGGTAA
	TAAAAACCAACACGTGGGGCCTGTGCTGTAAGGTGGCAGAGGGCGATGAC
	TCACCCCACTCATGCAGGTTGAGTCATTTCAAGGCAGAGTTGTGCCAGTT
	CAGTACCCAGTAATATTTTCCAGTCGACGAGTATCAGTGAACAGGAGATA
	ACCAGTCATTTCTAGATTCTGCTCAGAGTCCCAGCTTAGAGGCTCCACCA
	GCTCAAAGAGACGGGATGGCAAAACAGCCACCTTAATTTCCAGATCATCT
	GCCAGCTCATCTGCCAGCTGACACACAGCCCATGGCTCCACTATTGCCAG
	TGCTGTAGCTGCACCAGACCAATCTGGTTCAACTTTTATGTAACAAAGTT
	GTGATTTGTTTTTCAGTTGCCCGGGACTCCCAGGTTGAAGATCATGAGCA
	TGCCCTGATGAGCCAAGGCATGCAACCACAGGGGAACCTAA
	(SEQ ID NO: 237)

pARBI-633:	TGAGGTCTTGGTATGTTGCCCAGGATGGTCTCAAACTCCTGGGCTCAAGC	2541
chr10_3_	AATCCTCCTGCCTCCACCTCCCAAAGCGCTGAGATTATAGGCATGAGACA
Exogenous_89	CAGAGCCCAGCCACTGTCCGCATTTCTTTCCTGGCTTCCTTACTGGGTTC
	TCTACTTTCACTCTTGCCTTCTTCCTCTCTTCCACCAGCATAAGTTTTAG
	AAACTGCACTTCTGATCATGCTGCTCTGCTGCTTAAAATCCTTCATGCAG
	ATCATGTAAGACCTTCCTGATCCAGTGCTGCCTTGCCCTCTAGAACCCAG
	GGTGCCTTTCTCCCCTCTGCAGTTCTACTGCGCCACCTGCAGTTTCTCTC
	TCCTGTGTTCATGTGTCTACTCCCTCTGAATGGTAGGCTCACACCCTCCA
	CCTGGCCAACTCTTACTAAATCTTGGGCTTCAACTCAAGGATCACCTTCA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatTGGTTCACTC
	CACCAGGCTGGGCTGTGTGTCCTGCCCAGTTCCTATAGTGCCCTAACTCA
	CTTTTTTAAAAAAATACTTTAAGTTCTGGGGTACATGTGCAGAACATGCA
	GGTTTGTTACATAGGTATACACTTGCCATGGTGGTTTGCTGAAGCCATCA
	ATGTCATCTACATTAGGCATTTCTCCTAATGCTGTCCCTCCCCTAGCCTC
	CCACCCCCCAACAGGCCCCAGTGTGTGATGTTCCCCTTCCTGTGTCCATG
	TGTTCTCGTTGTTCAGCTTCCACTTATGAGTGAGAACATGCGGTGTTTGG
	TTTTCTGTTCCTGTGTTAGTTTGCTGAGAATGATGCTTTCCAGCTTCATC
	CATGTCCCTGCAAAGGACATGAACTCATTCTTTTTTATGGCTGTCCATTA
	TTCCATGGTGTATGTGTGCCACATTTTATTTATCCAGTCT
	(SEQ ID NO: 238)

pARBI-634:	CCTTCCACCCCCTTCCTTAATAGTTTTCCTCCTCCGCCTCCTGCACGGCC	2541
chr10_1_	TCCGCCTCCGCCTGACCGTCCTCGGAAACCTCCCAGCCGCAGCCCGGCCC
Exogenous_92	TCCCCAGCGGCCTGAGTGGCCTCCTCCCGCGGCGCCCCCCAGCTCCGCAC
	CTCCCCAGCCCCGCCCGAGGCGCGCCCAGCGAGCGTGACCCCGACCCAGG
	GCCACGGCTGCGCCCGTAGGATCGCGGGCGCGCGGGTCTCCATGAGGGAC
	TGGGAGAGATGCGTCACCCGCTAATCCCTCAACTGGGTCGCACCCGGTCT
	GCCTTGGTTGGTCCCTTCTGATGGCGGAGGCGGGACCTCGACTTGGTGGC
	CAATGAGGAGCCTCGTGGGGGTGCTCTCGGCTGCCATGGCAACGGAGGGG
	CCGCCCGCTTCCCCGCGGGGCGAGGCCGGCTCTCCCAGGACTGGCCACAT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTGCAGTCAC
	GCGCTGTGGCCCCAGTCCTGTTAGCATGAGGTGGGGGTCAGAAGTTGAGG
	AACAACTCGGACCTAAAGCCTTGACAATTGCCAACAGTGTAGACAAGTCC
	CAGCATGCCCAAAATTTATAAGAGAAGGCTGCCTGGAAGAGGGACACGAT
	GAGGAGGGTCTGCTGAAACGGACAAAGAAACCCAGTTCAGTGCAGTGGAG
	TGGACATGGCACGGGCAGGGCACGGAGTGGGGTCGGTGCTTAGTAAGCGG
	ATTAGGGTTTCCAAGCCAAGACCCACCCAGGGCAGGATGGGGAACCAAGG
	TGAGCAGGTGCGCTGAATTGTGGGTCTCACACTGTCCTTCAGTGTCCCGC
	AGGAAGAGAGAGCTAAGGATCACCAGGGTCATTCCCCTGCCTCAGGCAGC
	CTGCACTCCACCTTAGGTACAGTCATGTCCGGTCTTCAGCA
	(SEQ ID NO: 239)

pARBI-635:	TGATCCTCCCACCTCAGTCTCCCAAAGAGCTGGGATTACAGGCATAAGCC	2541
chr10_2_	ACCTTGCCCCGCCAGTTTTTAGCCTGTCAGCTCTTTGAGGGACACTTGTT
Exogenous_91	ATGGTCATACCCACAGCTTTGACCCTTACCAGGTGGTCAGGTGGATGAAT
	GAATGAGTAGAAAGAAGGAAGAGAAGGCAGGAGGGAGAAGAGGAAGAATG
	AAGGAAGGGTTGAGTTTGTTCTGGAAGCTCCCAGCTTCCATCCGCACCAC
	ACTCTCCCTCTGTCCCCAGGACACCAGGGAACTGACTCAAGGCTCTCCTC
	TTACCAGGTGCTGTGTGGGGTCCAGGGAGAAGAGCCCATTTGAAATGGGG
	CACTGGTCTAAACTCTGGACCTGCTGCTCACTATTGACTGAACTTAGCCA
	CTTAAATATTCTCCTCTATAAAATGGGAGTGACCATAGCAACTACCTCGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTGAATTGTA
	GGGAGACCCAAAAAATGTATATGAATACATTTGTCAACTAAAGAGTGTTA
	GGGATTATCTCAGTGGAGGGATAGGCAGTGCAGGCTCTGGAACCAGACTT
	CTTGTGTTCACATCCCTGCTCCACTGCTTGGAGACCTTTGGCAAGGTCCT
	TAACTCCTCTGGACCTCAGTTTTCTCATCTGTAAAACAGGGATTATACTA
	GTTCCTACCTCACAGAGTTGTGAAGATTAAATGAGATAATGCATGAAAGG
	CTTTTCAATAAGAGCAGGGCACACATTAGGCATGATGTCCATGATCAAGT
	GCCTAATATGTGCCTGCTCTCAGGAAGGATGCTGTGAACTACTTCACACT
	AAAGTGTAAATGAATGATAAGATCTACTATGCTCCACTCATGCCTGTAAT
	CCTAGCACTTTGGGAGGCCGAAGCAAGTGGATCACCTGAGG
	(SEQ ID NO: 240)

pARBI-636:	GGTGAGGTCACCCTGGGTACCTGGAGTTACTCAGAGTGACACTAGTACAC	2541
chr10_3_	GCCTGGCAGGAGTGATGGATGAGCTAGGCTCCAGGAAAGCAGGTGGGGCT
Exogenous_93	GGAAACCACCCAAGACAAGGAAATTGTTGGGTTTGAAATTCCAGGTAAGC
	AGAGTATGGCCTGAGAGCAGCGGCAGAGGCTGAAAGTGGGCTTGGTCTCG
	GTATTTTTGAGGCTGAGGTAGCTCCAACTCTCTCCCTCTGAGTCAGCACC
	CCACTTAAGACAGAAATACTGAGATCTGCGACCCCAGCCTCCCCCACAGC
	AACTCCACAGTCCCCAAACCTTTGCTCCGCTGGGTCCTCCCAAGTATGGT
	AGCTGACACAGCCCTGAGCAGCCCACTGTCCTCTGCCCTGCCAAGTCTTC
	TCACTCTTGTCACTTTGTCCTACATCATTTCTTTGTCTGGCACCCCTCCT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatAGAATTGGT
	GCCCCAGAGGTGGGAAAAACCTACCCTGCTCACTGCTCTATCTCCTGGGC
	TTAGCTCAGACTCTGGCATACGTGAGTGCTTAGTAGAAACTTGATGGGGT
	ATTAAAATTGAGACCTGGGTGGGTTCTCACATTAAATTTCTAACACTCCT
	TAGGTGGCTTGGGCCCACCCCTCTGAGCCCTGTTTCCACATCTGTAAAGT
	AGCAAACCATCGCCATGAAGAACAGGGAAGAACCAGGTCAGCAGGCAGGG
	CGGATGAAGCATCCAGCCAGTTCTAGGAAGTTTCCGATGGCTAATCCTTC
	AGATGCAGCTTGTAAGCAGGTCAAATACAGAATAGGAAACTGAGGCGCAA
	CGAAGTCATGCTTAGAAGTCTGTCCAGGGAGACCAGTCAAGGCCTCCCCC
	ACACCCTGCAAGCCCTTCTAGGAGCTCTGGTTAAGTCACTC
	(SEQ ID NO: 241)

pARBI-637:	ATCTTCAAATTGTAGTCTTTGTAACAACCAAATAACCTTTTGTGGTCACT	2541
chr11_1_	GTAAAATTAATATTTGGTAGACAGAATCCATGTACCTTTGCTAAGGTTAG
Exogenous_99	AATGAATAATTTATTGTATTTTTAATTTGAATGTTTGTGCTTTTTAAATG
	AGCCAAGACTAGAGGGGAAACTATCACCTAAAATCAGTTTGGAAAACAAG
	ACCTAAAAAGGGAAGGGGATGGGGATTGTGGGGAGAGAGTGGGCGAGGTG
	CCTTTACTACATGTGTGATCTGAAAACCCTGCTTGGTTCTGAGCTGCGTC
	TATTGAATTGGTAAAGTAATACCAATGGCTTTTTATCATTTCCTTCTTCC
	CTTTAAGTTTCACTTGAAATTTTAAAAATCATGGTTATTTTTATCGTTGG
	GATCTTTCTGTCTTCTGGGTTCCATTTTTTAAATGTTTAAAAATATGTTG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatACATGGTAG
	TTCAGTTCTTAACCAATGACTTGGGGATGATGCAAACAATTACTGTCGTT
	GGGATTTAGAGTGTATTAGTCACGCATGTATGGGGAAGTAGTCTCGGGTA
	TGCTGTTGTGAAATTGAAACTGTAAAAGTAGATGGTTGAAAGTACTGGTA
	TGTTGCTCTGTATGGTAAGAACTAATTCTGTTACGTCATGTACATAATTA
	CTAATCACTTTTCTTCCCCTTTACAGCACAAATAAAGTTTGAGTTCTAAA
	CTCATTAGAATTGTTGTATTGCTATGTTACATTTCTCGACCCCTATCACA
	TTGCCTTCATAACGACTTTGGATGTATCTTCATATTGTAGATTTAGGTCT
	AGATTTGCTAGCTCCAAGTAATTAAGGCCATGTAGGAGAGCATGGTAACC
	ACAGATAGAACTGGTATTATCCCAAGTGGTCTGCAGACTGC
	(SEQ ID NO: 242)

pARBI-638:	TTACAGCACAAATAAAGTTTGAGTTCTAAACTCATTAGAATTGTTGTATT	2541
chr11_2_	GCTATGTTACATTTCTCGACCCCTATCACATTGCCTTCATAACGACTTTG
Exogenous_97	GATGTATCTTCATATTGTAGATTTAGGTCTAGATTTGCTAGCTCCAAGTA
	ATTAAGGCCATGTAGGAGAGCATGGTAACCACAGATAGAACTGGTATTAT
	CCCAAGTGGTCTGCAGACTGCTGAGTGGGGATGGGATCTGCTCTCTGTTG
	AGAGTTGGTAATCATTGGTTTGAAATGTGATGAAACCACTCAAGCCAATG
	AAGGTGGGTGTGTAGGTGGGGAGTACTTTGCCATAATATTTTAAAACATT
	ACCTGGTTAGAGTTCTAAGTGGTACTTATTTTTGTTTGGTTAGGGGAAAG
	CCTGAATAAAAACAGAAATGGACACATAATATGCATATTCCATAGTCTTT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGGGAGGCTG
	GAATGTGCCTGGGATTTGGGTCTAAGTGTATGCGTAATTCTTACCTCACT
	AAAGAATTTGCCTTGTTTTTTTCCTTTTGGTGAGTGACTAAAACGTCTGG
	GCTTCCCTGTGTGCGTGCTACAGTAAGCAAGCAGAGGCTGTGCAAAGGTG
	TGAGCAGGATCACGTGGAATCTGGAGGATACATCTTGGCTTGCAAACTGC
	CTCTGTCTCCTGGGTGGGACTGTTCTGTCCTTGCACTGCTGTTCTGTGTT
	ACCTCTTGGGGTGTAAGGTTTTGCTTACAGGAGACAAACTTTGGGCGTAG
	AATGGAAGCCACTGCCAGCCTCTGTGCTGAGAAGGAAGGTGCTTGTTTCA
	AAGGGAGCAGCAAGGGAGGCTTGTTCTACTCACCTGGGCCTGTTTGCCTG
	AGAAGGGGAGATAAGGGCTGAACTGGGACTAGCCAGGGGGA
	(SEQ ID NO: 243)

pARBI-639:	TGGGGCTTTGGGGAATTTAGTGCGTGGGTGAGCCAAGAAAATACTAATTA	2541
chr11_3_	ATAATAGTAAGTTGTTAGTGTTGGTTAAGTTGTTGCTTGGAAGTGAGAAG
Exogenous_98	TTGCTTAGAAACTTTCCAAAGTGCTTAGAACTTTAAGTGCAAACAGACAA
	ACTAACAAACAAAAATTGTTTTGCTTTGCTACAAGGTGGGGAAGACTGAA
	GAAGTGTTAACTGAAAACAGGTGACACAGAGTCACCAGTTTTCCGAGAAC
	CAAAGGGAGGGGTGTGTGATGCCATCTCACAGGCAGGGGAAATGTCTTTA
	CCAGCTTCCTCCTGGTGGCCAAGACAGCCTGTTTCAGAGGGTTGTTTTGT
	TTGGGGTGTGGGTGTTATCAAGTGAATTAGTCACTTGAAAGATGGGCGTC
	AGACTTGCATACGCAGCAGATCAGCATCCTTCGCTGCCCCTTAGCAACTT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatAGGTGGTTG
	ATTTGAAACTGTGAAGGTGTGATTTTTTCAGGAGCTGGAAGTCTTAGAAA
	AGCCTTGTAAATGCCTATATTGTGGGCTTTTAACGTATTTAAGGGACCAC
	TTAAGACGAGATTAGATGGGCTCTTCTGGATTTGTTCCTCATTTGTCACA
	GGTGTCTTGTGATTGAAAATCATGAGCGAAGTGAAATTGCATTGAATTTC
	AAGGGAATTTAGTATGTAAATCGTGCCTTAGAAACACATCTGTTGTCTTT
	TCTGTGTTTGGTCGATATTAATAATGGCAAAATTTTTGCCTATCTAGTAT
	CTTCAAATTGTAGTCTTTGTAACAACCAAATAACCTTTTGTGGTCACTGT
	AAAATTAATATTTGGTAGACAGAATCCATGTACCTTTGCTAAGGTTAGAA
	TGAATAATTTATTGTATTTTTAATTTGAATGTTTGTGCTTT
	(SEQ ID NO: 244)

pARBI-640:	CGACCAACCCATCAAACTCCCCGCCCCCAGCACTTTTATTTCTCCTCTTT	2541
chr11_1_	AGGAAGTACACTTCAGTATCTTTGGCACAGTGCATGAGCACGACTAAAGT
Exogenous_94	AAAACATCGCAGAAAACATAGCTTTAGTCTACCCTTCGTGTCCTAAAAGG
	AAAACCAGTAGCTTCCCAGGCCACCGGAAGGGCAACACATGTCCTCTGCA
	GTTTCTGCACACGGGAAGGTAAAGACAGAGAGAGGACCTACTCCTCAACA
	CAGAAACATTTCAAAATCTTTCCTCGCCTGCAACCCAAGCTGAAGTCATT
	CTCCCCAGAAATAACAAAAGTTGGAAGAGAAGCCGGAGACAGGATAGGTG
	CAGGAAGCCCACACTTTGAGGGCAGCACTCAGACACCCTCTCCTGTGTGC
	AGGACGTGCCGAATGTTCAGGTGCAATGAGAATGAGCCATGCTTGGCTTA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCGAGGGCAA
	TCTGGCCCATCAAGTGGCCTTCGCCTCTGGGAGTAACAAAAATGCACTTC
	AAAATAGCTTCTGTAATCAAGCTGCATGGGTGGAGTACTCCCCAGCTGAC
	TCCAGGAAGTTCTCTATCCAAAGCTATTCATTAGGCCAGAGCTGTGCAAA
	TAATTAGTCACCCACTTGCTCCATAACCCTCCATGACAGCCCAGGCATTG
	AGTCCAGGTGGGACCATCAAGCCATGCTCTGGTGGCTCATGCATTATCAT
	AGAAATGGGAGGCTTTATTTATTTTACTAAAAAGAACAAAAACAACAGAC
	TGCTGTCCTTTAGACAATAGGATCACGTCATCTGAGCCCTCTGTGCCCCA
	GGTGACAAGCCCAGCCCCAAGTTCTCTTTCCTCAGCCTCCCCACACATGT
	TCTGGAGGAGATGGGCCCAGCAGGCTGCTCTGAGGCCTGGC
	(SEQ ID NO: 245)

pARBI-641:	TCACAGAATCTTGTTTGAGCTAACAACCAGTTATTCTACCCAAAGTAAAG	2541
chr11_2_	AGTAACTTAAATTTTCCCATTGTTCTTCCAGGCTGGAAGATGTAAGAAAC
Exogenous_96	ACACACAGTATAGTGTAGGTTTCCTCCATAGTTAAGTACCCCAGAGCTAG
	GCTGAAATCCAGTGTTGGATTGTTTCCAACTTATAGTAGGGAACCGCCAA
	TGACATGAAAGAGCATTACCTTACCGGACTGATTCATATTCTACTTCCAG
	TCATAGTACAAATGATCACATGTCCACACCCACATGTGCTCTGATAAGTA
	GTCAATTGAGAGGAGTGAGTCAGGGAGCCGTAACTTTGCAGCCAACCTGC
	CAAGAAGAACTGATGCTTTTAGAAATTCAGCAGCTTTCATTGGCATAGAA
	GTTTCAGCCTTATAGGCCCAGGGTTTCTCTGAGGCAGAGGCAAACCCTGT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTGTTATGTT
	GTTATCTCAGGATTCTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTT
	GCCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCGCC
	TCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACT
	ACAGGCGCCCGCCACCACGCCTTTCTAAATTTTGTATTTTTAGTAGAGAC
	GGGATTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGAT
	CCGCCGCCCTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGC
	GCCCAGCCTATCTCAGGATTCTTAATGTAAAAACAGTTCAGTATGGAAAG
	CGTACTTATGACAGAGCTGTTGCAGAATGTGAAATCACCCATGTGCCTAA
	GTGTCTCCCTACTACCTGGAACACTAGACCACATGCAGCAG
	(SEQ ID NO: 246)

pARBI-642:	CAGCCCTGAACTCAGCCTTCACGGCCCTCCCTAAACACATGGGCCAGCCA	2541
chr11_3_	CAGGGAAGAAAAAAATGCCCTGTAGCACAGGAATCTAAAACATTGCTGTT
Exogenous_95	GTTCTAGTTAATAAAAGGACTTAGAGATTGAAAAGAAGTACCATCTGTAT
	GGCTGGCAACAGACAGCATGATTTTGATGACTGACTCTGGGGAGATCTGA
	GAAAACAGTACATAATATGTCCTTACCTCTGCTCCATCATTCATGACCCA
	AGCTCCTGCCCTGTCTTCTCAGGAAGATTCTTACAGTAACTCCAGTTTGG
	AATTCCCCTTTCATATTTGAAATAACAACAGTAATAGTGACCACTAATGC
	TTACCGAGTGTCCACTCTGTGCCAAGCATCGTGTTTTTATCATCTTTTTT
	GTTAGGCACTGTACATGGATTAATACAATTACAACCCACCACAACCCCAT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGAGATAAGT
	ACTTGTACTATCCTCATTTTATGGGTGATGATACAAGAAACAGAAAGGTT
	CAGCAACATGCCTAAAGCCACACAGCTACTATGAGGCAAAGTCTAGGTTT
	GAACTCAGAAATTCTGACTTCAGACTCACTTATCTTATTATACTTCACTT
	AGTATCTCCCATTAATTAATTCATTCATTCTTCCTTTTATTTGTTAATTC
	ACCAAATATTCTGGGAAGCTACTTGTCTAGACACTGTATGAAAAATGAGA
	ATGGATACAAAGCAACCTCAGACATGAACTCAAGGTCCTTACAAGCTTAA
	ACGTATATGATACATTTCCAAATAGCAATACTATGAGGACAGCTGATACT
	CACAACATAAGTCTTGGTGGTCACAGGAGATCTATCATAGGATTTCACGA
	AGAACCTGACACTGAAAACCAGAACTTGAGGGAAATAAAAC
	(SEQ ID NO: 247)

pARBI-643:	GTGTCCATCCTGCATGTCTCAAGTCACAATCCTCCAGATATTCAACCAAA	2541
chr15_1_	GTGCTTGATTCTGTTGGCACAAGGACCATGAAATCTTCAGTAGCTAAGGA
Exogenous_100	GACTCTTTGACAAATAGATTTATTGCATATGATGTAAAAGGGTCTCATTC
	AGAGAACTACACATTTACTACACATTTACTAGCTGTTAGATGTGAGAAAT
	TGAAGCTTTGAGAATTGTCATTTTGTAAGCACGCTGTAATAATTGTGTTC
	TCTACAAAAATGGAGAAATACTTAATCTTTGCAGGTTTTTATTAGCTTCG
	AAAAAGGGAATACAAATATTTTGATACCTGACTTTATTTTAAAGATACTG
	GCAAGCAAGGAAAGATACTCAGTTTGCTAAATTATAGCATAGATTTGAAA
	GACGGAAATTTTTTTTTGTTATTTTGATTCTTTCTGATTCAGAACCTGCG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTGAGTTTCC
	ATTCCTGGGATAGAGAGCCCTGCCAAAGCCAACTCAGTCTCCTGTTATTG
	CAGAAATTTAAAGGTTACTTGAGCTGATTGATACCAATTAAAATAAAAGC
	ATCTACTGCCATTTTATTAAACGCCCTATTTAATCTCCACATCCCAAGTT
	CATTCTCTCTCTCTTTTAAGGCTATACATGGGCCTCAACATTCTCTCTTC
	TTCAGTATCAGCTGTCCTCATCCCTATTCAAAGTCAGAATGACTTGGAAT
	CTATTCAGGGCTGCTACTTAATTGGATGAAGAAAGTACTCTGTTGCATGC
	TAACCTCCCAGATTTGAATTAGAACCAAGGTCCTGAATCTACACAAGACC
	TTTTTCCCTTTCCTTTCTGCATTTATTTCTTTTTTTTCTACATCTTTCTT
	TTTGAATTTTTTTTTTTTTTTTTTTCTGAGATAGAGTCTTG
	(SEQ ID NO: 248)

pARBI-644:	ATCATCAAAATCTTCATTTATACAAATCACGGGTATTAGAAATAAAATCA	2541
chr15_2_	GGTATTGTGTACAGTCAGATCCCAGGTTTACACAAACTAGAGGTTTCAAT
Exogenous_101	TAAGTTTCCTTCATTTTATAAAACCATGACACAAGCTGTAAATAAAGGAG
	CTCTGGCTTTAGGCCTTCTTCTGTTTATAGACAGTAAATTTTAATCCTCT
	GTCCCTGCAGACCAACTCAAAGCAGTAACCTTGGCTACCGTTGCCGCAGA
	AGAAACACACCCTGCAGATTTCCAGTTCTATATTCAGTCTTAGAAAATTG
	GTCATGTTGAAAGGGAAAAAACAATTTTACTTTGCCTCAGTTATTGACAC
	CAAGAAGCACTCCTCAGCCTGTTCAGAGGGGAAACAATGAGTCATTCATG
	CTGTCAGCCCAGGTGGTGCATGAATTCCAGACAGAGGCCGCTGAATTAAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCCGTGGAGG
	CGTCTCTCTGAGCAGAGCCCGCAATGCGCCTGCTTGGGGCTCCCTGCAGC
	CTCTGGGGGAGGCAGGGCGGCCCAGAGCAGGCCTGTGCTGGAAAGGAACG
	CGAAGCCCTGTAACCAAGCCTGTACCTCTGCAGTGCTAGTCCCAAGGGGC
	CTCCGAGCTGTTTGTCACCATGTGATTGGCTCAGGAGAGGGGTGGAGAAA
	TGAAAACACTCTGCCCAGGATATATTTAGTTGAAGTGCAGCTGGGGAAGT
	GCTTAAACAAGGGAGCTTTTGTCCTTATGTTGAAGTGTTTTTCTTAACTC
	CTCAAGGGTGAAAAACTTGAGCCACGTACTGATCCCATTCCCCCCCACCA
	CCCCCAATATATTTTCTCTTCTTTAGGAAATGCTCTTATTCTGAAACTTT
	AGAATTTTCTAGGGTTTGTTGCATAAGAGGAAACTGAATAA
	(SEQ ID NO: 249)

pARBI-645:	CTTTCCTTTCTGCATTTATTTCTTTTTTTTCTACATCTTTCTTTTTGAAT	2541
chr15_3_	TTTTTTTTTTTTTTTTTTCTGAGATAGAGTCTTGCTCTGTCGCCAGGCTG
Exogenous_102	GAGTGCAGTGGTGTGATCTTGGCTCACTGCAGTCTCCAACTCTGGTTCAA
	GCAATTCTCCTGCCTCAGCCTCCGGGTAGCTGGGACTACAGGCATACACC
	ACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCAT
	AGTGGCCAGGATGGTCTCCATCTCTTGACCTCGTGACCTGACCCCCTCGG
	CCTCCCAAAGTGCTGAGATTACAGGCATGAGCCACCGCGCCCGGCCTCTT
	TTTGAATTTTTTTAAAAAAACACCTAAAGTTTAGGAAAGTATAAGAGGCC
	AAAGAAACAAGAGTTCAAAGAAACAAGAGTGTTATACACGCACACTTGCA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatGAAAGGTAGT
	AAAATATCTGTATAGTTCTGGCTGTCAAGCTTTTGGACTGAGATATGCGT
	AAGCAAGGCAAAAAGATCCCATAGTCCAGGAATATCAACCAGTCCAGTTT
	CCCAAGGAAACTAAAAGTAACTGAAAATGAGAAGGGTGCCATATAGGAAA
	ATTGAAGGTGGGGCATAATTATTAATACACTGCTTTGGAAATGCTGGTAT
	GGAAGATTCATATATGGACTTCAAAGCATACATGTCTTATACTTAGCTAT
	GGGAAAATTATCATCAAAATCTTCATTTATACAAATCACGGGTATTAGAA
	ATAAAATCAGGTATTGTGTACAGTCAGATCCCAGGTTTACACAAACTAGA
	GGTTTCAATTAAGTTTCCTTCATTTTATAAAACCATGACACAAGCTGTAA
	ATAAAGGAGCTCTGGCTTTAGGCCTTCTTCTGTTTATAGA
	(SEQ ID NO: 250)

pARBI-646:	TGTCTTCACGGCACGGCCCCCGCTTCACCAGCTGCACTGTTTGATGAGCT	2541
chr16_1_	TTGCAGGTCCCAGATCTTATAAGCTCATGGTGATTGATCCAAATGATGCA
Exogenous_103	GAGGTCGGCCTAAAGTTAGAAGTGGGCCCCTCTCTGCCCCAAGACAGCCC
	TTCACCCCAATTCCATTCCCACAGTTTGGGCATCCACCCAGGCTGCCAAG
	CCAAGCGGGGGCTGCCCGGGTTAGCAGGGACCTGGCCATGGGCCTCCTCA
	GCTAGGGGCCGCCTCTCTGAGGAGTGGGTGCCCCGCCCCTCCGTGGGCCG
	CCTGGTTTCTCTTATTGGCAGCGTCTGTAGTCCCCTGGCTCTGTCACCCG
	CAGCTATTCTAGGCCTCTGGTTCCTTTCACTTTCTGCTCTGCGTCTTCCT
	GCCTCGGTGGTTCCCCACCATCCAGCCTGAGACCTCCCCGTTGCCCGCCC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggggggcaggacagcaagggggaggattgggaagacaatagcag
	gcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGTG
	CCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGGG
	GGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAAA
	CTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGGG
	GAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAAC
	GGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTCC
	TTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGTC
	GCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGTC
	TAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCCC
	TTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTGC
	TTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAGA
	TCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccaccA
	TGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGTC
	GAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGGG
	CGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACCA
	CCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTAC
	GGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACTT
	CTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTCT
	TCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGGC
	GACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGGA
	CGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAACG
	TCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAAG
	ATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACCA
	GCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCACT
	ACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGAT
	CACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCAT
	GGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaat
	aaagcaatagcatcacaaatttcacaaataaagcatttttttcactgcat
	tctagttgtggtttgtccaaactcatcaatgtatcttatTGGGTTTCTGT
	CTGCTCCTCTCCGTGGTGGCCGGCCCTGGCTCTGCCCCAAAGCCATGGAG
	AAGGCCAAATGCAGGCTGTAGAAAGGTCTGGGATCAGATCCCCCCATCCT
	TCCATGGCCACGTGACCGGGCCCGCCTCTTCCCTCTGAGCCTCACATCCT
	CATCTGAAGAGGGAATGCTGCTCATGCCCACCTTGCGGGGATGTGGGGAG
	GGGGTGCTGCCAGTGGAGACTCCCAGGGGACCCTCCAGGAGTCTCATCCT
	GACTCGAGACTGGGCACCTGGTGGGGGCACAGGCCCCCTCTCCCGCCATG
	GGACCGCCACATCCAGGCTCTCGTGGGTTGAGATGCTGAGGAAAGGAAAG
	AACAAAACCTGCTGGAGGAGCAGCGAACACGGCCCTCAGCTGGGTGACCT
	TGGGCAAGTCACTTCCCCTCTCTGGGCCTCAGTTTCCAT
	(SEQ ID
	NO: 251)

pARBI-647:	CTGAAGAGGGAATGCTGCTCATGCCCACCTTGCGGGGATGTGGGGAGGGG	2541
chr16_2_	GTGCTGCCAGTGGAGACTCCCAGGGGACCCTCCAGGAGTCTCATCCTGAC
Exogenous_104	TCGAGACTGGGCACCTGGTGGGGGCACAGGCCCCCTCTCCCGCCATGGGA
	CCGCCACATCCAGGCTCTCGTGGGTTGAGATGCTGAGGAAAGGAAAGAAC
	AAAACCTGCTGGAGGAGCAGCGAACACGGCCCTCAGCTGGGTGACCTTGG
	GCAAGTCACTTCCCCTCTCTGGGCCTCAGTTTCCATATCTGTGAATGAGG
	CAGCTGGACTGAAGAATAGAGAGTCACAAAGCAGAGTGACACAAACTGGG
	CTACAGGAAACCCTGGAGGCCCTCGACCCAGGCTGGGGCCGGGGATGGTT
	CTGCAAAGCCTCTTGGGAGAGGGTTGCCTGAGCTGAGTCTCCAAACAGAA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCAGTGGCCT
	TAAGTCACGGGAGATGAGCCAGAGCAGTCCAGAGGGCACGGTCAGCACAT
	GCTAAGGTCCTGGGGCACAGAGTACAGGGCTTGAGAAGGGTTCCTCTTGC
	TCCATGTGACTTTCATCATCCAACAGCCTGTGGTGGCACTTGCCTGTATC
	CCAGCTATCTAGGAGGCTGAGGTGGGAGGATTGCTTGAGTCTGAGAGGTC
	GGGCTTGTTCTCCCGGTGTTGGCAGAGTCCAGAGGGAGCAAGTGGAAGCC
	ACAGGTGTCTTGAGGCCTAGGCTGAGATCTAGCACATCACCGCGTCACTT
	CATCCCTTCATTTCATCCTATTGGCCAAAGCAGCCCAATTCTAGGGATGG
	GGATCTAGACTCAACTTCTTGATGGGAGAAGTAGCAAAGTCACACTGCCA
	AGGGCAGGGACACAGGGAGGGATGAAGAGTTAGGAATGGTT
	(SEQ ID NO: 252)

pARBI-648:	AAGCCACCTCCCTGCTCTGTTGCTGGCTCTCCTTGAAGACAAGTGTTTTT	2541
chr16_3_	CAATTAACCAAAGCGGTGCATGGCAATGTGATAGGGGAATGAAACACAGC
Exogenous_105	AACAGAATCAATGCCCCACGCTGGGCAATAGCCGACTTTCTGTTCGCTCC
	CATCCCTTCCTTCCCTCCCCGCCTCCTTCCCCTGCTCCTTCCATTCCACA
	AACATTTATTGAGCACCCGCTGTGTGCCAGCCACTGTTCTAGGCCCTGAA
	GACACAGAAGTGAACAAAAAAAAAGAGTCCCTGTGCACATCCTGGAGGGA
	CTTTCCCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTATACAGTGTA
	TGGAGACAGTGGATAATAAAAGCTGTTTATGAGGCACTTTCTCTGAGCTG
	TTCCATGTGCTTCACTTATACTCATTCAGCTAATCCTCAGGACACCCCCG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTGAAGTCAG
	TGATATTAGTCACAGAGGCCCAGAGAAGTGAAGTGACTTGCCCAAGGTCA
	CACAGCCAGCAAGAGGCCAAGCCCGGATTGAACCCCAGCCGCCTGGCTCT
	GGAGCCTGCAGCATAACCACAGCAGGGAACTGCCACCGGAGACAGACATC
	GACAGCCACTAGGAGATGTTAACCAACAGGCTTGTCTTCACGGCACGGCC
	CCCGCTTCACCAGCTGCACTGTTTGATGAGCTTTGCAGGTCCCAGATCTT
	ATAAGCTCATGGTGATTGATCCAAATGATGCAGAGGTCGGCCTAAAGTTA
	GAAGTGGGCCCCTCTCTGCCCCAAGACAGCCCTTCACCCCAATTCCATTC
	CCACAGTTTGGGCATCCACCCAGGCTGCCAAGCCAAGCGGGGGCTGCCCG
	GGTTAGCAGGGACCTGGCCATGGGCCTCCTCAGCTAGGGGC
	(SEQ ID NO: 253)

pARBI-649:	GGGGGCGGCCGCACGGCTAGAGCGGAGACCCCGCGCCCCCTCCGCCCGCG	2541
EDF1_1_	TGGCCCGGCCGGGGTGCGGGGCCCGGGGAGGCACGGGGGCTGCGCGTCGG
Exogenous_25	GGCGCAGCCGCCGCCCGCGTGTGCTCGGAGGCCGCGGGGCCCGGGCTCCG
	GGGTCCTCCCGACCTGCAGCCCCAGCGGCTACCGCGCCTCGCCAGGCCAG
	GCCAGGCCCCGACGTCGCCTTCCCTACGTCGCCGGCGCCCGGCCACGACG
	TCCCTCAGACGAGCCGAACGCCGAATGGCCCCGAGCACGGGAAGTGCCCG
	CCCCCCGCGTGCAGCCAGCCAATGGGACGCCGAAAGCGGGGAGGTGCCGA
	GGGGACGTAGCGTCGCCGCGCCAGGTCTCTAGCAGCTGCCGCTGAGCCGC
	CGGACGGACGCTCGTCTTCGCCCGCCATGGCCGAGAGCGACTGGGACACG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGTGACGGTG
	CTGCGCAAGAAGGGCCCTACGGCCGCCCAGGCCAAATCCAAGCAGGTGCT
	TTGCTGACTGAGGAGCGGCCGGGCCGGGCGGGGCGGACGCTgggccgggg
	ccacggaccgtggggcagggggctcggggaagggcaggcggggcctggga
	cagggcgcaggggacggggacaaggctggGGTGCCGGGGGCAGGACGGGG
	TTCGAAGGGCGGGGCGAATCGCAGGGGTAGGAGGACCGGGCCAGGACagg
	ggtgggaaggtggggggcggacccaggaggggatggacggacccaggagg
	cagggggCGGGCGACTGGAGGAGGAGAGGAGCAGGGAACCGGACGGGGCA
	AGGGGCAGGCGATAGGGCCGGGACCAGTGCCAGGGTGGGGGGGGGAGGGG
	ATAGGGGCAGGGACTGTTGGTGGGGACAGGTGTGAGGACAG
	(SEQ ID NO: 254)

pARBI-650:	ACGGCTAGAGCGGAGACCCCGCGCCCCCTCCGCCCGCGTGGCCCGGCCGG	2541
EDF1_2_	GGTGCGGGGCCCGGGGAGGCACGGGGGCTGCGCGTCGGGGCGCAGCCGCC
Exogenous_26	GCCCGCGTGTGCTCGGAGGCCGCGGGGCCCGGGCTCCGGGGTCCTCCCGA
	CCTGCAGCCCCAGCGGCTACCGCGCCTCGCCAGGCCAGGCCAGGCCCCGA
	CGTCGCCTTCCCTACGTCGCCGGCGCCCGGCCACGACGTCCCTCAGACGA
	GCCGAACGCCGAATGGCCCCGAGCACGGGAAGTGCCCGCCCCCCGCGTGC
	AGCCAGCCAATGGGACGCCGAAAGCGGGGAGGTGCCGAGGGGACGTAGCG
	TCGCCGCGCCAGGTCTCTAGCAGCTGCCGCTGAGCCGCCGGACGGACGCT
	CGTCTTCGCCCGCCATGGCCGAGAGCGACTGGGACACGGTGACGGTGCTG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatCGCAAGAAGG
	GCCCTACGGCCGCCCAGGCCAAATCCAAGCAGGTGCTTTGCTGACTGAGG
	AGCGGCCGGGCCGGGCGGGGCGGACGCTgggccggggccacggaccgtgg
	ggcagggggctcggggaagggcaggcggggcctgggacagggcgcagggg
	acggggacaaggctggGGTGCCGGGGGCAGGACGGGGTTCGAAGGGCGGG
	GCGAATCGCAGGGGTAGGAGGACCGGGCCAGGACaggggtgggaaggtgg
	ggggcggacccaggaggggatggacggacccaggaggcagggggCGGGCG
	ACTGGAGGAGGAGAGGAGCAGGGAACCGGACGGGGCAAGGGGCAGGCGAT
	AGGGCCGGGACCAGTGCCAGGGTGGGGCGGGGAGGGGATAGGGGCAGGGA
	CTGTTGGTGGGGACAGGTGTGAGGACAGAGGCAGGAGGTG
	(SEQ ID NO: 255)

pARBI-651:	CCCTGGAGTCGGTGTGAGGCAAAAGCAGAGGAGAGGATTTGGAATTAACC	2541
EDF1_3_	TGAAGAAAAACCATTTCAAAGCGGTAACCAGACCCCAGAGGCTGCCTGAA
Exogenous_27	CTCAAGGGGACATGGGAACCCAGGCTGTCCCAAGTTCACACACCTCAGGT
	CGTGGACTTCCAGAGTTTTCTCTCAGTTATGAGGACAGGCAGCTGTACTC
	ATGCCAACCAGAGCTGCTCTGGGAAGATGGCTGCCTCCCAGGGCTCCGGC
	CAGCACCGGTGCAGGCAGGCACTCAGCTGACAACGTCCCCGGGGGCGCCG
	CACACACCACACCCACCAGCACATGGACCCCACAGCACAGCCTCATGTTG
	CAAGCGGAAACACAAGTACCTACATTTCTTGGAAGTCTCCACATCTTCTC
	CTCGTCTCTGTGCCGCTAAGATAGCCTAGAAAATTAGAAAACATCAGTGG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTTTCTAAAG
	AGAAGATGTGCTTTATACACATCAGCTCCACTAGGACTGCTGCAAAACCA
	GGCGCGAAGCGTCGCCTGAGAACAGCAGCTTCTAGGGCCCCTGGGGTACG
	CACCCACACGCAGCTGGGTTTTGTGCGAGAGGCAGTGAGAGCCGGGCTGA
	CCTGGCTTCCCGAGGCATTCCCTGCAGGGGAACCAGGGGGGTGGAGCCCA
	CCCTCCCCGTGCTATCTGAACACCGGCCATCCCCCTCCCCAAACCCACAA
	CCCCAGGAGTGAGAGCCCCGGCGCAGCCTCACCGTGGCCAGGTCCTTCTG
	CGTAAGCCCCTTGCTCTGCCGACCTTGCTGGATCACCTTGCCCACCTCCA
	GGGTCACCCTGTCATGGTGCAGCTCCTCTGTCTCCCGGTCCAGCTTGGCC
	GTGTTCTTGGTAATAGAATGTTGTTTGTTCTGGCCAGCAGC
	(SEQ ID NO: 256)

pARBI-652:	CTCTTGCTTCAACAGTGTTTGGACGGAACAGATCCGGGGACTCTCTTCCA	2541
FTL_1_	GCCTCCGACCGCCCTCCGATTTCCTCTCCGCTTGCAACCTCCGGGACCAT
Exogenous_2830	CTTCTCGGCCATCTCCTGCTTCTGGGACCTGCCAGCACCGTTTTTGTGGT
	TAGCTCCTTCTTGCCAACCAACCATGAGCTCCCAGATTCGTCAGAATTAT
	TCCACCGACGTGGAGGCAGCCGTCAACAGCCTGGTCAATTTGTACCTGCA
	GGCCTCCTACACCTACCTCTCTCTGGTGAGTCCCCAGGACGCCCCTGGCC
	CTAATTTCCTCCAGCTGCGCACCTCCGGCCCTCACTGCACGCGCCAGCCT
	TCTTTGTGCGGTCGGGTAAACAGAGGGCGGAGTCCCCTTGGCCTCGCCTC
	CCGCTAACCATTGTTGCCTCCATCTCTTCCCGTAGGGCTTCTATTTCGAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatCGCGATGATG
	TGGCTCTGGAAGGCGTGAGCCACTTCTTCCGCGAATTGGCCGAGGAGAAG
	CGCGAGGGCTACGAGCGTCTCCTGAAGATGCAAAACCAGCGTGGCGGCCG
	CGCTCTCTTCCAGGACATCAAGGTAACTAGTGTGTGGGTAATGGACTACA
	TCTCCCAGCAGGCCGTGCGCGCGAGGAGCCTTGATTTGAGGGCGTAGGTG
	TCGCGTGGGCTTCTGGGAGATTGAGTTCGGTCTTGTGAGCCCTCTTAACC
	GCTGGAAATAGAGGCGCACCTCGTGCAGTGCCCACAACACGCGGCAGTCC
	ACACCGCTGCGTGGTCTTAGGGACGTATAGCTGTAAGAGCTAGGACAGGG
	TGCGGAGAGTGATAAATACAAGCTGTCACATGTCTTTGTGGCCTGGGCCT
	CTGACCCCCAACGACTCTTGGGAAATGTAGGTTTAGTTCT
	(SEQ ID NO: 257)

pARBI-653:	TGGGGCGGGGGGCTGAGACTCCTATGTGCTCCGGATTGGTCAGGCACGGC	2541
FTL_2_	CTTCGGCCCCGCCTCCTGCCACCGCAGATTGGCCGCTAGCCCTCCCCGAG
Exogenous_29	CGCCCTGCCTCCGAGGGCCGGCGCACCATAAAAGAAGCCGCCCTAGCCAC
	GTCCCCTCGCAGTTCGGCGGTCCCGCGGGTCTGTCTCTTGCTTCAACAGT
	GTTTGGACGGAACAGATCCGGGGACTCTCTTCCAGCCTCCGACCGCCCTC
	CGATTTCCTCTCCGCTTGCAACCTCCGGGACCATCTTCTCGGCCATCTCC
	TGCTTCTGGGACCTGCCAGCACCGTTTTTGTGGTTAGCTCCTTCTTGCCA
	ACCAACCATGAGCTCCCAGATTCGTCAGAATTATTCCACCGACGTGGAGG
	CAGCCGTCAACAGCCTGGTCAATTTGTACCTGCAGGCCTCCTACACCTAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCTCTCTCTG
	GTGAGTCCCCAGGACGCCCCTGGCCCTAATTTCCTCCAGCTGCGCACCTC
	CGGCCCTCACTGCACGCGCCAGCCTTCTTTGTGCGGTCGGGTAAACAGAG
	GGCGGAGTCCCCTTGGCCTCGCCTCCCGCTAACCATTGTTGCCTCCATCT
	CTTCCCGTAGGGCTTCTATTTCGACCGCGATGATGTGGCTCTGGAAGGCG
	TGAGCCACTTCTTCCGCGAATTGGCCGAGGAGAAGCGCGAGGGCTACGAG
	CGTCTCCTGAAGATGCAAAACCAGCGTGGCGGCCGCGCTCTCTTCCAGGA
	CATCAAGGTAACTAGTGTGTGGGTAATGGACTACATCTCCCAGCAGGCCG
	TGCGCGCGAGGAGCCTTGATTTGAGGGCGTAGGTGTCGCGTGGGCTTCTG
	GGAGATTGAGTTCGGTCTTGTGAGCCCTCTTAACCGCTGGA
	(SEQ ID NO: 258)

pARBI-654:	CTTTGCATAGTTTATCCTATTAGTAATCTATTCTGTCTTTGGAATATGTT	2541
PTEN_1_	TTGTGATGATGAAATAAATACTATAAATAGTATTATTCCTTTTGCATTGA
Exogenous_31	GAGTCCTGACGAAATGTCCATGTGACAGTTCATTTTGGGTTTAGCTCTAC
	CTCTAATATGTGACCTATGCTACCAGTCCGTATAGCGTAAATTCCCAGAA
	TATATCCTCCTGAATAAAATGGGGGAAAATAATACCTGGCTTCCTTAATG
	ATTATATTTAAGACTTATCAAGAGACTATTTTCTATTTAACAATTAGAAA
	GTTAAGCAATACATTATTTTTCTCTGGAATCCAGTGTTTCTTTTAAATAC
	CTGTTAAGTTTGTATGCAACATTTCTAAAGTTACCTACTTGTTAATTAAA
	AATTCAAGAGTTTTTTTTTCTTATTCTGAGGTTATCTTTTTACCACAGTT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCG
	CACCATCTTCTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGA
	AGTTCGAGGGCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGAC
	TTCAAGGAGGACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAA
	CAGCCACAACGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGG
	TGAACTTCAAGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCC
	GACCACTACCAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCC
	CGACAACCACTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACG
	AGAAGCGCGATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATC
	ACTCTCGGCATGGACGAGCTGTACAAatgattgtttattgcagcttataa
	tggttacaaataaagcaatagcatcacaaatttcacaaataaagcatttt
	tttcactgcattctagttgtggtttgtccaaactcatcaatgtatcttat
	GCACAATATCCTTTTGAAGACCATAACCCACCACAGCTAGAACTTATCAA
	ACCCTTTTGTGAAGATCTTGACCAATGGCTAAGTGAAGATGACAATCATG
	TTGCAGCAATTCACTGTAAAGCTGGAAAGGGACGAACTGGTGTAATGATA
	TGTGCATATTTATTACATCGGGGCAAATTTTTAAAGGCACAAGAGGCCCT
	AGATTTCTATGGGGAAGTAAGGACCAGAGACAAAAAGGTAAGTTATTTTT
	TGATGTTTTTCCTTTCCTCTTCCTGGATCTGAGAATTTATTGGAAAACAG
	ATTTTGGGTTTCTTTTTTTCCTTCAGTTTTATTGAGGTGTAATTGACAAG
	TAAAAATTATATATAAATACAATGTATAATATGATGTTTTGATGTATGTG
	TATATACATTGTGAAATGATTACTACAGTCAAACTACTTAACATATTCAT
	(SEQ ID NO: 259)

pARBI-655:	GCTACCAGTCCGTATAGCGTAAATTCCCAGAATATATCCTCCTGAATAAA	2541
PTEN_2_	ATGGGGGAAAATAATACCTGGCTTCCTTAATGATTATATTTAAGACTTAT
Exogenous_32	CAAGAGACTATTTTCTATTTAACAATTAGAAAGTTAAGCAATACATTATT
	TTTCTCTGGAATCCAGTGTTTCTTTTAAATACCTGTTAAGTTTGTATGCA
	ACATTTCTAAAGTTACCTACTTGTTAATTAAAAATTCAAGAGTTTTTTTT
	TCTTATTCTGAGGTTATCTTTTTACCACAGTTGCACAATATCCTTTTGAA
	GACCATAACCCACCACAGCTAGAACTTATCAAACCCTTTTGTGAAGATCT
	TGACCAATGGCTAAGTGAAGATGACAATCATGTTGCAGCAATTCACTGTA
	AAGCTGGAAAGGGACGAACTGGTGTAATGATATGTGCATATTTATTACAT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatCGGGGCAAAT
	TTTTAAAGGCACAAGAGGCCCTAGATTTCTATGGGGAAGTAAGGACCAGA
	GACAAAAAGGTAAGTTATTTTTTGATGTTTTTCCTTTCCTCTTCCTGGAT
	CTGAGAATTTATTGGAAAACAGATTTTGGGTTTCTTTTTTTCCTTCAGTT
	TTATTGAGGTGTAATTGACAAGTAAAAATTATATATAAATACAATGTATA
	ATATGATGTTTTGATGTATGTGTATATACATTGTGAAATGATTACTACAG
	TCAAACTACTTAACATATTCATCACCTCACATAATTATTATTCTCCCCCC
	AGGGTGAAAGCATTTAAGATCTACAAGCTACAATTTTCAATTATACAATG
	TTATTATTAACTATAGTCACTATGCTGTCCAGTAGAGCTTCAGATCTTGT
	TCATCTTGTGTTCCTCCCTCCCCACCCTCAGTCCCTGGAA
	(SEQ ID NO: 260)

pARBI-656:	ATAAATAGTATTATTCCTTTTGCATTGAGAGTCCTGACGAAATGTCCATG	2541
PTEN_3_	TGACAGTTCATTTTGGGTTTAGCTCTACCTCTAATATGTGACCTATGCTA
Exogenous_33	CCAGTCCGTATAGCGTAAATTCCCAGAATATATCCTCCTGAATAAAATGG
	GGGAAAATAATACCTGGCTTCCTTAATGATTATATTTAAGACTTATCAAG
	AGACTATTTTCTATTTAACAATTAGAAAGTTAAGCAATACATTATTTTTC
	TCTGGAATCCAGTGTTTCTTTTAAATACCTGTTAAGTTTGTATGCAACAT
	TTCTAAAGTTACCTACTTGTTAATTAAAAATTCAAGAGTTTTTTTTTCTT
	ATTCTGAGGTTATCTTTTTACCACAGTTGCACAATATCCTTTTGAAGACC
	ATAACCCACCACAGCTAGAACTTATCAAACCCTTTTGTGAAGATCTTGAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCAATGGCTA
	AGTGAAGATGACAATCATGTTGCAGCAATTCACTGTAAAGCTGGAAAGGG
	ACGAACTGGTGTAATGATATGTGCATATTTATTACATCGGGGCAAATTTT
	TAAAGGCACAAGAGGCCCTAGATTTCTATGGGGAAGTAAGGACCAGAGAC
	AAAAAGGTAAGTTATTTTTTGATGTTTTTCCTTTCCTCTTCCTGGATCTG
	AGAATTTATTGGAAAACAGATTTTGGGTTTCTTTTTTTCCTTCAGTTTTA
	TTGAGGTGTAATTGACAAGTAAAAATTATATATAAATACAATGTATAATA
	TGATGTTTTGATGTATGTGTATATACATTGTGAAATGATTACTACAGTCA
	AACTACTTAACATATTCATCACCTCACATAATTATTATTCTCCCCCCAGG
	GTGAAAGCATTTAAGATCTACAAGCTACAATTTTCAATTAT
	(SEQ ID NO: 261)

pARBI-657:	TAGTGACGGTATCAAGAGCAGCATCCCAGGTTGACTTTCTTTGGGGCAGG	2541
PTPN2_1_	ACCTTGCTTGTGTCTTAACCCTTGGTTCCTACccaagtttgtctctctag
Exogenous_34	tcctcaactctgaaagccacttgatatcttacacaattccttttttgcct
	gagaaaaaaaagtcagttttgatcatttacaaccaaaaatcctaactaac
	acaGACCTGTTTTTGAAATCAGGTAGATTGGAAGTCTTGGTTTACTTCTT
	ATAAGCCCGTCCGCTGTCTGTCTTGTAACATCCCAGGAGCAGACTTAACA
	AGGCCTTCCTGGAGCCTTGCTCTTTCTGTCTGCTTCCCTCATCTGctctc
	tctcctctctctTCACAGGGTCCACTTCCTAACACATGCTGCCATTTCTG
	GCTTATGGTTTGGCAGCAGAAGACCAAAGCAGTTGTCATGCTGAACCGCt
	gacgactgtgccttctagttgccagccatctgttgtttgcccctcccccg
	tgccttccttgaccctggaaggtgccactcccactgtcctttcctaataa
	aatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggg
	gggtggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatATTGTGGAGA
	AAGAATCGGTGAGTAATATTTAATATTTACAACTTAGTATACTGTATGTG
	ATCATTAGCATATAAAGATTTTCATTTTGGGGCCAATATTCATTCCTTAG
	TTTTGGCCTTTAATTGCTAAAGGCTAGCGGTCAAAGTGTTTCTGTCCGGA
	AAAACTCATGTATCCTTTTCCTTTCTTAAGTATTTTTATAACAATTGCAG
	ACCTTTCATCTCCAAGATAGAAATACAATGGAATAAATATGGACTAGCAG
	TGACATATAGATCTTTGGAATCCCTAGGAATCCTTATTGACCTATTGTCA
	ATAAGTCCTCTTCCAGCTTTAAGATCTTGTACTGTTCTACTTCAGATTTC
	TTACTTTATTCTACATTTCATAATTGCTGGTTTTTAATGATGATGAAAAT
	TTCCTAATCCACTTCTAATTAGATGTGGCAATGACATGCC
	(SEQ ID NO: 262)

pARBI-658:	CAGAATTTGAATATGATGTGGCTGACCATAGATACCTCCATTGCATTAAT	2541
PTPN2_2_	TCTGCTTCATAAAGTGTTTGATGCTTGCTTGTAGGTGTTGAATAGAGCCT
Exogenous_35	AATTAGCAGTAAGTAAACAGATCTagagcacagactttggcatctgaagg
	accttggttcaatgctgggactgccacttactagctatgggatctttggt
	ggatttttaacctttgaaagcctttcatccctcacagatataatggggaa
	gaaaatcgtttccattagtattgtgaggattaaatgattaattgatgtaa
	acaatgtgctttccatagtacttggcatatcataagtgcttcatGTTATT
	TTACGCTGGCTGGGAAGATAAGTTTTGCTGTGGAGAATTTAAGAGGGATA
	TTAAAATATATTTTTGTTATTTTAAGGAAATTCGAAATGAGTCCCATGAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatTATCCTCATA
	GAGTGGCCAAGTTTCCAGAAAACAGAAATCGAAACAGATACAGAGATGTA
	AGCCCATGTAAGTACTTGTGGGTTTGTGTGCATGTGTATTTTTTGGTTTG
	TTTTAGGAGGCAGGATGTAGTGAAAAGGAGGGCTTGGGGTCAGTGTTGAT
	AAATACAGTAATTTTTTTCCTATTTACGTAAGACACGTTCTTTAAGAATT
	TAAAGGTGTAGAATAGTGGAAGGAAAAATAATTACCCATAATTATTTCAT
	CCTTCAAACATAGGCACCATTATTTTGGTGTATTTCCCACAACCTGTTTT
	TCTTATGCACAGTTTTCCTTTCTTTAAAATAATTGTAATTATAGATGTCT
	ATATAATATCCATATGTATTTCCTTTTCATATCATTCCATCCCCTTTGTA
	AGTTTTGCTTAAAATAGTTATTGGTGTAGTTTGGTTTTTT
	(SEQ ID NO: 263)

pARBI-659:	ACCAGTTATCGTTTTGTAGGTAGACCAATCAATTCTTAGGTACCAAGAAT	2541
PTPN2_3_	CTGAATGATCCTTTTACTTTTAGGAAGGTAAGTACTTTATTCATTTAACT
Exogenous_36	ATGTTTACTCCTGGTCGATTTTTCAAGTCACAATGGCTAATGTGCTACAA
	ACAGAAGTGCTTCCTTTCCAGCACTATAGTAATAAACAAGATTGCATTTT
	ATACTCCTTACAAAAAAAGTAGAGAATAGTTTAGGATTTGTCTCAACTCT
	ATTATGATGCTAATTCATTTTTCTTATTTCTTCTGTCTTTTTATAAATAC
	CTAGAATATTAATATGAAGATAAAAACAGTAATTTTGAAATGACAGTTGT
	GGTTTATCATTCTCTATTTTCAGATGATCACAGTCGTGTTAAACTGCAAA
	ATGCTGAGAATGATTATATTAATGCCAGTTTAGTTGACATAGAAGAGGCA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatCAAAGGAGTT
	ACATCTTAACACAGGCAAGTAATACGATACCACGCAAATGTCTGAAAATG
	ATGTGTTTGTGCTTGTTCTGCTTTAAATCATAGGTAAAAGTATATCTTGA
	CTTCTTTTGGAAATGAAATGGTATTTCAGTTTTTTTCTGACGATGTAATG
	AATTATGGACATTATAAGGTTTTGAAGCTTTGAGTATTTAAGATAAAAGG
	CAAGTTATTTTTGATATTACACGTTCTGTGAAGGAAAATTCTTAGGAAAT
	GGCTTAGGCCAGTTCTTTGGCAGATTGTGTTCCTTACATTATATCTGACA
	CAGAGTGCTGCTTATGCTTCTTAGTGTCTTCTTTTCTCTTCCCATACCCT
	GTGGCAAAACCAGAGGCCCTGGACAGCTCTTCTGTAGCTCCCCCTGCCTC
	GCATATATCTTCAGAGAGTACACCAAGCCCTGGATGGTGT
	(SEQ ID NO: 264)

pARBI-660:	CCTGCTCAAGGGCCGAGGTGTCCACGGTAGCTTCCTGGCTCGGCCCAGTC	2541
PTPN6_1_	GCAAGAACCAGGGTGACTTCTCGCTCTCCGTCAGGTAGGTGGGCCCCCCG
Exogenous_37	CAACCCCGGGCATTTTGGCCACTCTCTTGTGCCATCCAGGCCCTGAACCA
	CTCATTCCTGGTTCCCCGTGGCAGTGCTGACTCCCCGTCTGTTCCCTTGC
	CCCCAACCCCCACACTCCCCATCCCTGTCTGTGCCCACCCATGCCCATGT
	GTGCCCCCACCCAGGACCTCAGCCGATCCCTGCCCTCCTGCCTCTACTCC
	TGCACCGACTGGCCTCACCGCCTGGTGCCCTGCAGGGTGGGGGATCAGGT
	GACCCATATTCGGATCCAGAACTCAGGGGATTTCTATGACCTGTATGGAG
	GGGAGAAGTTTGCGACTCTGACAGAGCTGGTGGAGTACTACACTCAGCAG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCAGGGTGTC
	CTGCAGGACCGCGACGGCACCATCATCCACCTCAAGTACCCGCTGAACTG
	CTCCGATCCCACTAGTGAGAGGTGAGGGCTCCGCACCCCCGCCATTCCCA
	AGCAGGGATGAGCCGGCTCCCACCCTGAACAGCCAGGGAGGCAGGGAGAC
	TGGCAGCCGGCGCTGCCTACCCTCCATCCCCTCCCCTCCCTGCACCAGCT
	GGGGCTCTCAATGTCCCTCCTCCCTGCTGTCCTGGGACCTGGTGTCTCAG
	AGCCTAACCTACCACCCTTTCCACCTAACCCCGAGGAAGCCACAGAAAGC
	TGCCTCGCCCTACTCCGGGAGCCCTGGCCGCTGCAACCCAGGTCCCACTG
	GAGACAGGGAGGCCACTGCTGGTGGCCAGCATGTCGTGCAGGCCAGCTCT
	GTTGTTAGAAAGCTCTTCTTCCTCTGGAATCGAGCCTGCCT
	(SEQ ID NO: 265)

pARBI-661:	CTGGGTTCGAAGCCCGGTTAGAACTCTGGAGGCTAGGATGGCTTGAACCT	2541
PTPN6_2_	GGGAGGTCGAGGCTGCAGAGAGCTGTAACCGCGCCACTGCACTCCAGCCT
Exogenous_38	GGGCAACAGAGCTCTGGAAGCTTGCCCTAGAGTCAGTCAAGGGCCCTAGG
	CCAGTGAGTAACAGCTCAGCGTCAGTTTCCTCATCTATAAAATGGGGGTA
	ATATCATACCTAGCTCTCAGCATGTTTGTGAGAGACCTAAATGAGGTGGT
	GGATTTGGAAGCATGTAGCGCAGTGCCTGGCACACAGTAGGTGCTTGATT
	TCCGGCCCCTCTCTGTGAATGTCTCTGCTCAGCGCCTTCCCCTGTGGCCT
	GGGTCTTACCTTCCCTGACGCTGCCTTCTCTAGGTGGTACCATGGCCACA
	TGTCTGGCGGGCAGGCAGAGACGCTGCTGCAGGCCAAGGGCGAGCCCTGG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatACGTTTCTT
	GTGCGTGAGAGCCTCAGCCAGCCTGGAGACTTCGTGCTTTCTGTGCTCAG
	TGACCAGCCCAAGGCTGGCCCAGGCTCCCCGCTCAGGGTCACCCACATCA
	AGGTCATGTGCGAGGTAAGGCAGCCAGGCGGCGGGGGAGCCTCTGCTGAG
	GCTCCTGTCTGTGACCACAGTGTGGGTGGCAGGGAGGGTCTGCCTGGGCT
	TGAATTCAAGGCTGGGGACCCAGGGAGGGAGACTCAAGTCCTGTGAATGG
	CCTAATTTGGCTCCCCCCAGGGTGGACGCTACACAGTGGGTGGTTTGGAG
	ACCTTCGACAGCCTCACGGACCTGGTGGAGCATTTCAAGAAGACGGGGAT
	TGAGGAGGCCTCAGGCGCCTTTGTCTACCTGCGGCAGGTCAGGGGTGGGC
	CCAGCTGCCTCCCCACTTCCCCTGAGCTGTCCCCCAGATGT
	(SEQ ID NO: 266)

pARBI-662:	TGTCACATATGTGCAATGCCATGCTCCTGAGCCTTTGATTGCAGACGTGT	2541
PTPN6_3_	GGGAAGTGGGCCCCGTCCCCACCCCCAGTGCCACCCTGCTCTGCTTCTCT
Exogenous_39	TCCCTTGCTGTGCTCTAAAACGAGAAGTACAAGTGAGTTCCCCCAAGGGG
	TCGGCCGCGCCTCTTCCTGTCCCCGCCCTGCCGGCTGCCCCAGGCCAGTG
	GAGTGGCAGCCCCAGAACTGGGACCACCGGGGGTGGTGAGGCGGCCCGGC
	ACTGGGAGCTGCATCTGAGGCTTAGTCCCTGAGCTCTCTGCCTGCCCAGA
	CTAGCTGCACCTCCTCATTCCCTGCGCCCCCTTCCTCTCCGGAAGCCCCC
	AGGATGGTGAGGTAAGGGCCTGCCACCCACGGTAGACAGGAGGCAAGGGT
	GCCTGGTGCCCACGGGACCCCTCCTCACTGCCCTGCCTGGGCCGCCCAGG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTGGTTTCAC
	CGAGACCTCAGTGGGCTGGATGCAGAGACCCTGCTCAAGGGCCGAGGTGT
	CCACGGTAGCTTCCTGGCTCGGCCCAGTCGCAAGAACCAGGGTGACTTCT
	CGCTCTCCGTCAGGTAGGTGGGCCCCCCGCAACCCCGGGCATTTTGGCCA
	CTCTCTTGTGCCATCCAGGCCCTGAACCACTCATTCCTGGTTCCCCGTGG
	CAGTGCTGACTCCCCGTCTGTTCCCTTGCCCCCAACCCCCACACTCCCCA
	TCCCTGTCTGTGCCCACCCATGCCCATGTGTGCCCCCACCCAGGACCTCA
	GCCGATCCCTGCCCTCCTGCCTCTACTCCTGCACCGACTGGCCTCACCGC
	CTGGTGCCCTGCAGGGTGGGGGATCAGGTGACCCATATTCGGATCCAGAA
	CTCAGGGGATTTCTATGACCTGTATGGAGGGGAGAAGTTTG
	(SEQ ID NO: 267)

pARBI-663:	TCTTTAGCTAATGTTCTGTAGCTTGTTTTAGATCTGTGTCTACATATTAT	2541
PTPRC_1_	ATGTATCTCTGTATGCATCAATATTTGTATATATGCATGCATATATGTGT
Exogenous_40	ATGTATATTTATGAATACATATACACACCATATACATACACTTATGTATG
	GTGTGTGCATATGTATGTGTAGATATATGTACATACACACTATAGTGGAC
	TGGGGAGTTAGTATACTGGGAGGAGCATACATTTAGGGTATGATTCACAT
	ATTTATTTTGTCCTTCTCCCATTTTCCATTAATTAACAGGATTGACTACA
	GCAAAGATGCCCAGTGTTCCACTTTCAAGTGACCCCTTACCTACTCACAC
	CACTGCATTCTCACCCGCAAGCACCTTTGAAAGAGAAAATGACTTCTCAG
	AGACCACAACTTCTCTTAGTCCAGACAATACTTCCACCCAAGTATCCCCG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGACTCTTTG
	GATAATGCTAGTGCTTTTAATACCACAGGTTGGCACACAAAAGTTGTTAA
	CTTAAATATCAGGGAATGTCATTTAGAAAATTCTACAGTTATCAGTACAA
	CTTGTCTTTAAATTATTTGCACAGTTTCTAAGTATGTGATTTTATTCAAG
	TGCAGAAATTGCAGGAAATTAGTATCTGTGAAATATAGATCGACTGAAGT
	AATTAATGCATGTTGTTAGGGAGTGGAGAGAGAAAAGAAGGGAAGCAAGA
	TCTCCAAGGACAATCAGGAGGGGAAATTTGTTCTAGTATCCTCTGATCTA
	TACACACTCGCCATGATTCTCCCGCTTGGCTTCCCGCCACCTGGACAGAT
	GAGAATTTCCCTAGTTCAGAGATTATCAGTTCTACTCTCCTTGGAAGGTG
	TCTTAAATGGGAGTCTTCCCATTTCTTTGTTTCACTCTAGA
	(SEQ ID NO: 268)

pARBI-664:	AGGGAATTTTTATATGTTGGTCATATTATATCCCTAGCATGTGGCATAAT	2541
PTPRC_2_	GTCTAGCACAAAATAGGTGCTCAATTAATCATCATTATCTAAATAAATAA
Exogenous_41	TGCATTTGGGAAAAAAAAGTTTCAAAAGTTTTTCAAAAGTCTTTTGCAGG
	CTTGAAATTAATCCCAATAGTGATCCTTTAGTCTGTTATGTTTCTGATTT
	AGCCTGGGGATTCAAAAAATAAATAACATAATTTTGATATATTTGGGCTT
	TGTAAACATGGTACTAAGAGAGGAAATATAGTTTCATTAGGGTAAAAGCT
	ACTGAAAATTGCCACTTGGTGAATGTTCTATCATAGACTTGAGGTACATA
	TAAAAATCTAATATATGTTTACATTAATATGAATGAAATTTGAAATTTTC
	TAAGAGATTTTTGTTTCTTCTTTGCAGGGCAAAGCCCAACACCTTCCCCC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatACTGGTAAG
	AATTAATATTTATATTTTTACTAATTTTATTTTCTTGTTGCAAAGTTTAT
	ATATTTAACTACAATTTTCTATTATTAACACTGAAATTATTTTTAAGGAT
	AAATTTTATAATCATGAGTGATTCTTGACATTCACTTGTTCTTAAACTTT
	CTGCTTATACGTTATAGAGTTTAATAACTACCTAAACATGTTATTAAATT
	TGTATATATATTTTGTGTATAAATAGTAACTTTTCCCAAACTTGACAGTA
	AATCACACAACAGGTTTCTACTCTCTTTTAATATTTTAAGACTATAAAAA
	AATGCATTTAAATTAGATAACAAAATTTTATAGTCTGAAAGCAGGTTAAC
	AGCTGTCTATGTATGTTATAGATATGTAGATAACAGATTTGCATATGTCT
	ATATTTCTTTAAGAGTATGTTGCTTTTTTCAATGGTATGCA
	(SEQ ID NO: 269)

pARBI-665:	CCTTTAGCACCATAAAGAAACTAAATTATTTAGATGTTTTTATGAGAACA	2541
PTPRC_3_	TATCAAAAAGTACTTTTCTGTCATCCAATACTTCCACAAATAAATCATTA
Exogenous_42	GTTCTTGCTAATCTTCATCTGGCATAAAAATAATGACATCAACTTTCTTC
	ATGTAATTTCCCACTTAATTCCTTTACTAGGAGCAATATCAATTCCTATA
	TGACGTCATTGCCAGCACCTACCCTGCTCAGAATGGACAAGTAAAGAAAA
	ACAACCATCAAGAAGATAAAATTGAATTTGATAATGAAGTGGACAAAGTA
	AAGCAGGATGCTAATTGTGTTAATCCACTTGGTGCCCCAGAAAAGCTCCC
	TGAAGCAAAGGAACAGGCTGAAGGTTCTGAACCCACGAGTGGCACTGAGG
	GGCCAGAACATTCTGTCAATGGTCCTGCAAGTCCAGCTTTAAATCAAGGT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTCATAGGAA
	AAGACATAAATGAGGAAACTCCAAACCTCCTGTTAGCTGTTATTTCTATT
	TTTGTAGAAGTAGGAAGTGAAAATAGGTATACAGTGGATTAATTAAATGC
	AGCGAACCAATATTTGTAGAAGGGTTATATTTTACTACTGTGGAAAAATA
	TTTAAGATAGTTTTGCCAGAACAGTTTGTACAGACGTATGCTTATTTTAA
	AATTTTATCTCTTATTCAGTAAAAAACAACTTCTTTGTAATCGTTATGTG
	TGTATATGTATGTGTGTATGGGTGTGTGTTTGTGTGAGAGACAGAGAAAG
	AGAGAGAATTCTTTCAAGTGAATCTAAAAGCTTTTGCTTTTCCTTTGTTT
	TTATGAAGAAAAAATACATTTTATATTAGAAGTGTTAACTTAGCTTGAAG
	GATCTGTTTTTAAAAATCATAAACTGTGTGCAGACTCAATA
	(SEQ ID NO: 270)

pARBI-666:	aaggaaaaaggcactgagtgctggggggtgctggggtgggctgcagtgat
PTPRCAP_1_	agacatcagggtagaggttaaggtcaggttcagcctcactggggtgaagt
Exogenous_43	ttgagcacggtgagcaggccatgcagcccgggggaggggaggatgggagg
	aggtggagctttccgggcagagggaacagccagtgcgaaggccccaggca
	ggtggcttaatgcagctgttgggggaggtgagtggtagggaggaggctgg
	agggatgggggctgatctcacagggccagagcctggttgaccaaataagg
	ccttggccttttctGCTTGGCTGTCCCAAGAGGATCCCAAAGAGAAAAAA
	ACGAAAGTGGTCTTGGTCACCCAGCCTGCCCCACACCAGGCCCCACCCCA
	GGTGCTGAGCCCTCTGAGCCCCTGCCTGTCTCCCACAGGCTCTGCCCTGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatACCTTAGGGC
	TCGGGATGCTGCTGGCCCTGCCAGGGGCCTTGGGCTCGGGTGGCAGCGCG
	GAGGACAGCGTGGGCTCCAGCTCTGTCACCGTTGTCctgctgctgctgct
	gctcctactgctgGCCACTGGCCTAGCACTGGCCTGGCGCCGCCTCAGCC
	GTGACTCAGGGGGCTACTACCACCCGGCCCGCCTAGGTGCCGCGCTGTGG
	GGCCGCACGCGGCGCCTGCTCTGGGCCAGCCCCCCAGGTCGCTGGCTGCA
	GGCCCGAGCTGAGCTGGGGTCCACAGACAATGACCTTGAGCGACAGGAGG
	ATGAGCAGGACACAGACTATGACCACGTCGCGGATGGTGGCCTGCAGGCT
	GACCCTGGGGAAGGCGAGCAGCAATGTGGAGAGGCGTCCAGCCCAGAGCA
	GGTCCCCGTGCGGGCTGAGGAAGCCAGAGACAGTGACACG	2541
	(SEQ ID NO: 271)

pARBI-667:	aaggtcaggttcagcctcactggggtgaagtttgagcacggtgagcaggc	2541
PTPRCAP_2_	catgcagcccgggggaggggaggatgggaggaggtggagctttccgggca
Exogenous_44	gagggaacagccagtgcgaaggccccaggcaggtggcttaatgcagctgt
	tgggggaggtgagtggtagggaggaggctggagggatgggggctgatctc
	acagggccagagcctggttgaccaaataaggccttggccttttctGCTTG
	GCTGTCCCAAGAGGATCCCAAAGAGAAAAAAACGAAAGTGGTCTTGGTCA
	CCCAGCCTGCCCCACACCAGGCCCCACCCCAGGTGCTGAGCCCTCTGAGC
	CCCTGCCTGTCTCCCACAGGCTCTGCCCTGCACCTTAGGGCTCGGGATGC
	TGCTGGCCCTGCCAGGGGCCTTGGGCTCGGGTGGCAGCGCGGAGGACAGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGTGGGCTCC
	AGCTCTGTCACCGTTGTCctgctgctgctgctgctcctactgctgGCCAC
	TGGCCTAGCACTGGCCTGGCGCCGCCTCAGCCGTGACTCAGGGGGCTACT
	ACCACCCGGCCCGCCTAGGTGCCGCGCTGTGGGGCCGCACGCGGCGCCTG
	CTCTGGGCCAGCCCCCCAGGTCGCTGGCTGCAGGCCCGAGCTGAGCTGGG
	GTCCACAGACAATGACCTTGAGCGACAGGAGGATGAGCAGGACACAGACT
	ATGACCACGTCGCGGATGGTGGCCTGCAGGCTGACCCTGGGGAAGGCGAG
	CAGCAATGTGGAGAGGCGTCCAGCCCAGAGCAGGTCCCCGTGCGGGCTGA
	GGAAGCCAGAGACAGTGACACGGAGGGCGACCTGGTCCTCGGCTCCCCAG
	GACCAGCGAGCGCAGGGGGCAGTGCTGAGGCCCTGCTGAGT
	(SEQ ID NO: 272)

pARBI-668:	cagtgcgaaggccccaggcaggtggcttaatgcagctgttgggggaggtg	2541
PTPRCAP_3_	agtggtagggaggaggctggagggatgggggctgatctcacagggccaga
Exogenous_45	gcctggttgaccaaataaggccttggccttttctGCTTGGCTGTCCCAAG
	AGGATCCCAAAGAGAAAAAAACGAAAGTGGTCTTGGTCACCCAGCCTGCC
	CCACACCAGGCCCCACCCCAGGTGCTGAGCCCTCTGAGCCCCTGCCTGTC
	TCCCACAGGCTCTGCCCTGCACCTTAGGGCTCGGGATGCTGCTGGCCCTG
	CCAGGGGCCTTGGGCTCGGGTGGCAGCGCGGAGGACAGCGTGGGCTCCAG
	CTCTGTCACCGTTGTCctgctgctgctgctgctcctactgctgGCCACTG
	GCCTAGCACTGGCCTGGCGCCGCCTCAGCCGTGACTCAGGGGGCTACTAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCACCCGGCC
	CGCCTAGGTGCCGCGCTGTGGGGCCGCACGCGGCGCCTGCTCTGGGCCAG
	CCCCCCAGGTCGCTGGCTGCAGGCCCGAGCTGAGCTGGGGTCCACAGACA
	ATGACCTTGAGCGACAGGAGGATGAGCAGGACACAGACTATGACCACGTC
	GCGGATGGTGGCCTGCAGGCTGACCCTGGGGAAGGCGAGCAGCAATGTGG
	AGAGGCGTCCAGCCCAGAGCAGGTCCCCGTGCGGGCTGAGGAAGCCAGAG
	ACAGTGACACGGAGGGCGACCTGGTCCTCGGCTCCCCAGGACCAGCGAGC
	GCAGGGGGCAGTGCTGAGGCCCTGCTGAGTGACCTGCACGCCTTTGCTGG
	CAGCGCAGCCTGGGATGACAGCGCCAGGGCAGCTGGGGGCCAGGGCCTCC
	ATGTCACCGCACTGTAGAGGCCGGTCTTGGTGTCCCATCCC
	(SEQ ID NO: 273)

pARBI-669:	ATAGAGTAGGGCGGGGGATGCCATGGAGAGGCTCCATGGGGGAGGGCCGG	2541
RPS23_1_	GGAAGCGCCGCTCCAGGAGGCACGTGGTCCGGCGCGGAAGGGGCCCATGA
Exogenous_46	GGCGTGGAGGCCGCCGAGGTCGGGGTACCGAGGGACGCAGGGAGGCCAGC
	GCTTCCTCCCGGGCATTCGAGCGGGGCCTCGTCCTTCGGGAGAACACATT
	CTCCGGAGCCCTCTTCGAACGTTTATTAGTCGGTTCAGGGCAACTTGAAG
	GCCAAATGTTTGGCCCACAGGCCAATAAATAGTACGAGAGCCAATCGGCT
	TAAGGGTTTATTCCAGGTGAGGCGAGTGTCTTAGAAGATGGGAAACACGT
	AGATGGCGTGTTTTTACGGAAGAACTAAAATATTTAATTTTTAGGCAAGT
	GTCGTGGACTTCGTACTGCTAGGAAGCTCCGTAGTCACCGACGAGACCAG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatAAGTGGCAT
	GATAAACAGTATAAGAAAGCTCATTTGGGCACAGCCCTAAAGGCCAACCC
	TTTTGGAGGTGCTTCTCATGCAAAAGGAATCGTGCTGGAAAAAGTGTAAG
	TCCATTGCTCCCGTCAAGTTTTAGTTTATTATAGGAATTCGAGACATGAA
	CTTACGAATTCTTGTTTTGAAAGTAATTGCAGGTTTTTGTGTAGTAGTAT
	TCATTTGGGCATTGTGGGGTAAAATTGCAAAGCGTTTGTTCTATTTAAAA
	GTTGGTAAAATTAGTTTTTGGGAATTAGGTAGTTAAGGTTTTAATTTAAC
	GTTGGCCTGGAAGGAATTGGAGAAGATACTAGCAATGATGAAGTAAAGGA
	CACAAACACCTTTACTGTGGGAGTTGTTATAAGTAAATGGCACGTGTCAG
	CTATTGAACTTTATCGACTTGATAAAACTAAGGTGAAGAGA
	(SEQ ID NO: 274)

pARBI-670:	CAAGCGGGACTTGGGGTCTTGGGGACGGGCGGGCGGATGCGAATAGAGTA	2541
RPS23_2_	GGGCGGGGGATGCCATGGAGAGGCTCCATGGGGGAGGGCCGGGGAAGCGC
Exogenous_	CGCTCCAGGAGGCACGTGGTCCGGCGCGGAAGGGGCCCATGAGGCGTGGA
47_48	GGCCGCCGAGGTCGGGGTACCGAGGGACGCAGGGAGGCCAGCGCTTCCTC
	CCGGGCATTCGAGCGGGGCCTCGTCCTTCGGGAGAACACATTCTCCGGAG
	CCCTCTTCGAACGTTTATTAGTCGGTTCAGGGCAACTTGAAGGCCAAATG
	TTTGGCCCACAGGCCAATAAATAGTACGAGAGCCAATCGGCTTAAGGGTT
	TATTCCAGGTGAGGCGAGTGTCTTAGAAGATGGGAAACACGTAGATGGCG
	TGTTTTTACGGAAGAACTAAAATATTTAATTTTTAGGCAAGTGCCGCGGA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCTTCGTACT
	GCTAGGAAGCTCCGTAGTCACCGACGAGACCAGAAGTGGCATGATAAACA
	GTATAAGAAAGCTCATTTGGGCACAGCCCTAAAGGCCAACCCTTTTGGAG
	GTGCTTCTCATGCAAAAGGAATCGTGCTGGAAAAAGTGTAAGTCCATTGC
	TCCCGTCAAGTTTTAGTTTATTATAGGAATTCGAGACATGAACTTACGAA
	TTCTTGTTTTGAAAGTAATTGCAGGTTTTTGTGTAGTAGTATTCATTTGG
	GCATTGTGGGGTAAAATTGCAAAGCGTTTGTTCTATTTAAAAGTTGGTAA
	AATTAGTTTTTGGGAATTAGGTAGTTAAGGTTTTAATTTAACGTTGGCCT
	GGAAGGAATTGGAGAAGATACTAGCAATGATGAAGTAAAGGACACAAACA
	CCTTTACTGTGGGAGTTGTTATAAGTAAATGGCACGTGTCA
	(SEQ ID NO: 275)

pARBI-671:	TTGTATATCCTTTTTAAAGTTATTCTTTTTAGTTAATTGCTCTATGTGTA	2541
RTRAF_1_	TTGAGACTAGGAATCAGAAAGCTTAGATTCTAGTCCCAGGTGTAAGTTGT
Exogenous_49	GTAACCCTTGGCAAGTGTCAATCTCTAGGCCTCAGCTTTCTCATCTATAA
	AATGAGGAAGTTGTCGTATTCTATTTTTTTTCTTAAGATGATACACTTAA
	ATGTTCCCTTCTGTTGGGTTATATAATTGCATCAAAAGTGTAGTAATGTT
	ATTAAAAAATTGTTAGAGATCCAAACTAAGGTCTCTTTCAACTCTCCCAT
	TCTTTTTTCTGTGACTTTATGGTAATAATGAAACTGGTGGTTTTCTTTTC
	TTCCCCCTCACAGTATCTCAGAGATGTTAACTGTCCTTTCAAGATTCAAG
	ATCGACAAGAAGCTATTGACTGGCTTCTTGGTTTAGCTGTTAGACTTGAA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatTATGGAGATA
	ATGGTACGTTTTGTGGGGAATGTGTATTTTAAAGAGAGAGGAAAGATGGG
	AAAGGGAGTGTGAAAATGTAGGGAACTTTGCAGTTTGTTTTGTCTAGTAC
	TATTTTACCTTTGGTTTATTCTTATCACAAGTTAAAAGCACTTTTATTGT
	CTTTCATTGGTGTTTATATATTTCTGTTAGAATTTGGAAATGGTGCCCTC
	TGGAGAAGGCTAATTGACTGTCTTCTCACAGAGTAACACTACTTTGATAA
	TATGGTCTGCACCTTAGCCTTTCAAATTAAATTGTTTTTAGTGTCCCAGA
	ATTGATGGGACTTTGAAGTGTTGTTGCAGTAGGTAATTTCTCAAAAGACT
	GAAACATGTCTAATGCCAATATACATTAATACTCTATAGGCCAGAATATA
	TTACTTATGTTTACTGTCTTAGCACAGATACTTCTATGGT
	(SEQ ID NO: 276)

pARBI-672:	GCACCTGTTATGTAGGAGGAGTAATAAAATGAATGAATGCACTCAAAACA	2541
RTRAF_2_	CTAAACAGTAATTCTGTAATCCAACGGGAGGTACAGCGAATACCAAAAGC
Exogenous_50	CTACATATACTATTCTCTGCATGCTATAGCAAGAAAGAAAGGAAAGTGGC
	TTCCCGGTGGTTTTCTGCCTATTGTACAACCAGGAAGCTGACAATAAAGT
	TTATTTGAGCGTCGACGTGCGCCGACGTGGCCCCGCCTCCCCAGCCGGAG
	CCGCGATTGGTGGGCATTTGCCGGCGGCCACCGCTTTTAAGCCACGATTG
	GCGAAGGCCGCCGTCATTTCGGAGCGACTCAGCGCCTGCCCGCCCTCTCG
	CCGCGTCGCCGGTGCCTGCGCCTCCCGCTCCACCTCGCTTCTTCTCTCCC
	GGCCGAGGCCCGGGGGACCAGAGCGAGAAGCGGGGACCATGTTCCGACGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatAAGTTGACG
	GCTCTCGACTACCACAACCCCGCCGGCTTCAACTGCAAAGGTGAGGCGGC
	GGCCTCAGCCCGGCCGCGTGTCCCTGACCTGGGCGGAGGTCCCAGCCTCA
	GTGCCCGCACCCCACCTCCCCGTCGGGACCCTCGGCGGCCTGGTTTCCGC
	CGGCAGCCTCCGGGCCCCTCTCCTCTGGGTCGCCACGTACCTCGGCTCTT
	CGCCGCCCCTTCCCGCCTTTAAAGCCCTCTCACCTACTCCTGTCTCGGCA
	TGTTACTTTCTGCACTTGCTTAACTCCAAGCATCACGTAACTACCTTCTC
	TGTACATAAAAGGGAGAGCATTCGTCTTTCTCACTCACTATTCAACTCCA
	TGGTTCCCTGGGTAATTAGGCGATACCTTGAGCACCTGCTAATTATGGGC
	CAGCGCGGTGCTGGATTCTGAGGAAGGTGCTGAGTAACTTG
	(SEQ ID NO: 277)

pARBI-673:	CACTAAACAGTAATTCTGTAATCCAACGGGAGGTACAGCGAATACCAAAA	2541
RTRAF_3_	GCCTACATATACTATTCTCTGCATGCTATAGCAAGAAAGAAAGGAAAGTG
Exogenous_51	GCTTCCCGGTGGTTTTCTGCCTATTGTACAACCAGGAAGCTGACAATAAA
	GTTTATTTGAGCGTCGACGTGCGCCGACGTGGCCCCGCCTCCCCAGCCGG
	AGCCGCGATTGGTGGGCATTTGCCGGCGGCCACCGCTTTTAAGCCACGAT
	TGGCGAAGGCCGCCGTCATTTCGGAGCGACTCAGCGCCTGCCCGCCCTCT
	CGCCGCGTCGCCGGTGCCTGCGCCTCCCGCTCCACCTCGCTTCTTCTCTC
	CCGGCCGAGGCCCGGGGGACCAGAGCGAGAAGCGGGGACCATGTTCCGAC
	GCAAGTTGACGGCTCTCGACTACCACAACCCCGCCGGCTTCAACTGCAAA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGGTGAGGCG
	GCGGCCTCAGCCCGGCCGCGTGTCCCTGACCTGGGCGGAGGTCCCAGCCT
	CAGTGCCCGCACCCCACCTCCCCGTCGGGACCCTCGGCGGCCTGGTTTCC
	GCCGGCAGCCTCCGGGCCCCTCTCCTCTGGGTCGCCACGTACCTCGGCTC
	TTCGCCGCCCCTTCCCGCCTTTAAAGCCCTCTCACCTACTCCTGTCTCGG
	CATGTTACTTTCTGCACTTGCTTAACTCCAAGCATCACGTAACTACCTTC
	TCTGTACATAAAAGGGAGAGCATTCGTCTTTCTCACTCACTATTCAACTC
	CATGGTTCCCTGGGTAATTAGGCGATACCTTGAGCACCTGCTAATTATGG
	GCCAGCGCGGTGCTGGATTCTGAGGAAGGTGCTGAGTAACTTGAAGACTA
	GTTCACTGCCTGCCAGGAGCTAAAGGGACGAGGGGTGGAAG
	(SEQ ID NO: 278)

pARBI-674:	CCGGGTTAGGCATAGGCCCTCCCGGATCTTCCGCGGTGTAAGGAGAAGGC	2541
SERF2_1_	CAGCGCCCCTGTGATAGGCCCAGAGCCCCCACTCCACAAGCCAGCCCATC
Exogenous_52	CCCCACGGAGACCCAAACCGTCCACACACACCTTGCCAGCTGTTTGGGCC
	CCACGCCGCCCCAAAACACGCCTCCAGCTGGCCCCTTGGGACCTCCCTTC
	TCTAGTCCGTATTTTGACCTGGCCCGTGGCAGATTCGCCACTCCCCCCTA
	CCCCAAGCAGCCTGGGCCTCGATGGGCCGTTGTCGGGGCCCGGAGATTGA
	AGTGGTGTTGGATCCTGCTGCTGGCCGCGCTGGGGTAGAAGGGTCGCCGG
	TGTGTGGGCAGAGCGGCCCCCGCGTCTCACCTTTAATTTTCTTTCCTTAG
	GCGGTAACCAGCGTGAGCTCGCCCGCCAGAAGAATATGAAAAAGCAGAGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGACTCGGTT
	AAGGGAAAGCGCCGAGATGACGGGCTTTCTGCTGCCGCCCGCAAGCAGAG
	GTAGCCCCAGGGAGGGGAGGGAAAGGGACGGTGGAGACCTGGGTTAGACC
	AAGGGTTATAGAAGGAAAGAGAGCTACCTCAGGGCTTGAATGTGGACTAG
	TCGTGAGGAGCAGAGTGCATTGCTTCCTCTAGGGTTTTATTTCCTCCCCA
	CCCTCCAAATTGTTAGCTCACAGCCTTACAGGAAAGGACGGGGGCGGGCG
	CCTGCCCTCAGTCTGATTTCTGAGCGTCCCTGGGTCTGACCTTAAGGGCA
	AGGGCAGGGAGCTTCACATTTCAAATACAGTTGTGGTTACGGCAGCCCAG
	TACTTTTGGCCCTCCTTGCTGTTCGGTTCTCCTCCCTTCTCCCAACCTCC
	TCACTGGTGTTGCTGGGTGTGGTCCTCAATACAGAATAGAG
	(SEQ ID NO: 279)

DARBI-675:	AATCGAGCCCTTTGCCCACGGCTACTTCACGGGACCACCCTCCCGGGTTA	2541
SERF2_2_	GGCATAGGCCCTCCCGGATCTTCCGCGGTGTAAGGAGAAGGCCAGCGCCC
Exogenous_	CTGTGATAGGCCCAGAGCCCCCACTCCACAAGCCAGCCCATCCCCCACGG
53_54	AGACCCAAACCGTCCACACACACCTTGCCAGCTGTTTGGGCCCCACGCCG
	CCCCAAAACACGCCTCCAGCTGGCCCCTTGGGACCTCCCTTCTCTAGTCC
	GTATTTTGACCTGGCCCGTGGCAGATTCGCCACTCCCCCCTACCCCAAGC
	AGCCTGGGCCTCGATGGGCCGTTGTCGGGGCCCGGAGATTGAAGTGGTGT
	TGGATCCTGCTGCTGGCCGCGCTGGGGTAGAAGGGTCGCCGGTGTGTGGG
	CAGAGCGGCCCCCGCGTCTCACCTTTAATTTTCTTTCCTTAGGCGGTAAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCAGCGCGAG
	CTTGCCCGCCAGAAGAATATGAAAAAGCAGAGCGACTCGGTTAAGGGAAA
	GCGCCGAGATGACGGGCTTTCTGCTGCCGCCCGCAAGCAGAGGTAGCCCC
	AGGGAGGGGAGGGAAAGGGACGGTGGAGACCTGGGTTAGACCAAGGGTTA
	TAGAAGGAAAGAGAGCTACCTCAGGGCTTGAATGTGGACTAGTCGTGAGG
	AGCAGAGTGCATTGCTTCCTCTAGGGTTTTATTTCCTCCCCACCCTCCAA
	ATTGTTAGCTCACAGCCTTACAGGAAAGGACGGGGGCGGGCGCCTGCCCT
	CAGTCTGATTTCTGAGCGTCCCTGGGTCTGACCTTAAGGGCAAGGGCAGG
	GAGCTTCACATTTCAAATACAGTTGTGGTTACGGCAGCCCAGTACTTTTG
	GCCCTCCTTGCTGTTCGGTTCTCCTCCCTTCTCCCAACCTC
	(SEQ ID NO: 280)

pARBI-676:	TTCAAAAGGAATCTTTTTGTTTCAACTATTAGGATCTTTTTAAATCAAAT	2541
SLC38A1_1_	ATGTATTTTAATGGTGTACACCAGACCTGAAGAAAAAGATCACAGAAGGA
Exogenous_55	ATTTCCCCTTTGTAAGATAGAGGTAGTTAAAAATAAGCCTTATGACCTAA
	TAGGTTAATTGTAATGCTCTGGTAGCCAACTTGAAAAAGGAGAAATGATG
	GTTGCATCTCACATTTTAAAATGTTAAGAATTTGTTTTGTAATGAGGATA
	CCTTAACCCCTGAAGGCCAAAATGACTATTTGTGTGAGTTTGAGAAAGGC
	ACATAGTAACTTGGGGAACAGTCAATAGAATGACAAAATCTTGACTATTT
	TAACTTTCTGAACCCTGTCATTTCTTGTGTTCTCAAATTTGATTTTTAAA
	TAGGCTGCATGGTGTATGAAAAGCTGGGGGAACAAGTCTTTGGCACCACA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatGGGAAGTTCG
	TAATCTTTGGAGCCACCTCTCTACAGAACACTGGAGGTAAAAAGAACATG
	CTTTTCTTTACATAACTTGAAACTAATTCTGGTGGATGAGCGGCCACATG
	AATTTTAACATAATTCAAGCAGTTATCATCCTCATTGCTAAAATGGCACA
	GGGAAAGTAAAGCAGAGACAGCAGTCACTTATTTAAAGCCACAAATCCTG
	CTAGAGTAGCTGAAGTTGCCTTTGTGTCTTACTGACAGTTGGTCTAAGAA
	CGGGCTGATAACTTTTTATGTAGCTTGCAACATAAGCCTTCGTATCTTCT
	TTCTAAAAATGTTCTCATTTTCCTTCAGCAATGCTGAGCTACCTCTTCAT
	CGTAAAAAATGAACTACCCTCTGCCATAAAGTTTCTAATGGGAAAGGAAG
	AGACATTTTCGTAAGTTATAGACCATTITTTTATGATATA
	(SEQ ID NO: 281)

pARBI-677:	TAAAGATGTCAAGCTTCAAATCATTATCATAAGGTTAAATATATTACGCA	2541
SLC38A1_2_	TGTCTTTACAGCAAGTTTATTTCTGATCGTGAAAGTAGAAGAAGTCTCAC
Exogenous_	AAACAGCCATTTGGAAAAAAAGAAGTGTGATGAGTATGTAAGTATCATTA
56_57	TAATGAAGTATGCTTATTTTTTTAATCATATAAATTGGGACAAATCTTTT
	TAATTCAAGTAGCATAGTACCAAAAGCATAACTACCTGTATTCACCAGGA
	TATTCCTCATACCTTATGTATTTTCTCTTGAAATCCATTCAAGGAAATAA
	CTAGATAACTAAGAATGGATTTTCTTGAATTTTACTTCCATATTGGTTCC
	TGAGAGTGCATTAAAGGCTTTGGCTTGATGAACTTTCTTGGGGATTATTT
	TGCTTAGTGTCAATGTTTGTTTCTTTGTTCAGATTCCAGGTACAACCTCC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTTAGGCATG
	TCAGTTTTTAACCTAAGCAACGCCATTATGGGCAGTGGGATTTTGGGACT
	CGCCTTTGCCCTGGCAAACACTGGAATCCTACTTTTTCTGTGAGTATTGA
	CGTGCCGGTACTTTCCATTTTAAAACTGAACTTTTTGTATGTTTCTGTTA
	TTACATAGAAGAAATGTGAAATATTTATAAATAGTTTTTTTATTAACTTG
	GCTAAGTTACAAGTACATACTTTGATATTTATTGCTTGAGTGATTTTCCA
	AACTGTACCTAATGCTTACAACAAAGAGGAAGGAGAAAATCTTTTTATTA
	ATCAAAAATACTGAAATAAGCATTTGTGAAAAGGATTAAAACATTTGAAA
	ATAACTTTTTTTGGTATTTTTGGAGTCTACCTGTGACTTTAAATCTCAGT
	TAAAATATTAAGAGGTGTTTAACCCCAGCCAGTCACCACTT
	(SEQ ID NO: 282)

pARBI-678:	ATCATTCTTCACACTAGTTCCTTTTCTGACTCTTCAGTCACCTCCAGAAT	2541
SMAD2_1_	TAATATCCTTAGAAGCATCTCTAAAATGAGTTTGATTTACTAAACATAGA
Exogenous_58	AGTTGACAAAGTTTTTCAAGTATAACTGCATAAACTCTCTTTTTTAAAAA
	ATCAGTTTTTCCCAAGTTGTTAGCCTTTCATTGGCATTTGAGTCATTTAT
	GTGACATATTTATAAGAAACATCTGCTAGTGCTGCTGCATACTTTTATCA
	GATCCATTAAATAGTACATTTTTGTTCTTGATTCTCACTAAAACTAACTA
	AATGGCTGTCATTCTTTTCTTTATGCTTTTATTGTACTAATTTAGCCCAT
	TTGACTGCACttttttttttttttttttAAAGTTCCCTCCTTTCTTTTCC
	CCTTGCTTCCCAACAGGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatAAAGGATTGC
	CACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTCACAGTCAT
	CATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAA
	GGATGAAGTATGTGTAAACCCTTACCACTATCAGAGAGTTGAGACACCAG
	GTAGGAATATTGCAAGTTTTTTTCTTGGTTTTGAATTAAATGCCTGAACT
	TCAGTATATTTAAGTACTCTTGTGACCCAGGAAAATTTTAGTGTAAATTC
	TAATAAATTACCTTAAATTGTGCATATTATTTGGTGGTAATTAAAAtttt
	tttatttttaaaaatttttAATGAGAAAACATATCTGTTTCTTGGAATAG
	CATATGATTTGGCATGAAAGTGCATATCCAGGAAATCCTGTAGATTGGCA
	GTCTGCTCAGCGCTATGCTGATGTGCTTCTACATGTCCCT
	(SEQ ID NO: 283)

pARBI-679:	TTCTATATTAAAAATCAGTTGACATCTGTTTTTAGATAATTTTTTAAAAA	2541
SMAD2_2_	ACTGGATTATAAAATGAAGCACTTAGTAAAGCTGATGGCAGAGGTTTTAG
Exogenous_59	ATCTTTTGAATACAGGAAAGTGGTAAGGGCATTATAGGTATGATTCATTG
	AGCTAGAGGGCGTTGGTGTTCACATTTTAAAAACATAATCATGACTTATC
	TGGAGTCACATGTTCCATTTTATTGGCTTCCTTCATATAGAAAATATAGT
	AACCAGCACTACATGCCTGTGAAAAAGTGAAGCAATTGTATATTTTCTGG
	GTGAAGGAAGTATTCTGTACATTCTCCATGTTTTACATCATGGTATTTTG
	AATAACCATGCTTCCATGTTCACATCAATTTTTTGTTTTTCAATTTATGC
	ACAGCACTTGCTCTGAAATTTGGGGACTGAGTACACCAAATACGATAGAT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCAGTGGGAT
	ACAACAGGCCTTTACAGCTTCTCTGAACAAACCAGGTGAATATTCTGCCC
	TCTGTCGAATCTTAGAGATCTTGTGGGAGGGGGGTATATTTTGAAAGACC
	TATATGGGGTTGCTTAGTATAATTTTGCCTAGGATGTTTCCTTAATGTAA
	AATAAGGCATAGCATTTAAAATATCTGCTTGCCAGTATAAAAAATATATT
	AAATGTTTCAGCTGATGTTTTAATCAATGCAATTCTAGTTTGAATCTTCT
	TTAAATTACTGTATCCCCTAAAGAATAATAATTTTGATAACTATATATTT
	ATTTTAGCTTGAGATCAGATTATAATCTGTTGTTGGCCTAATTTTTAAGT
	AGATACATGATGAGTTTTGCTAAATTTCTTGTTATCAGAATCTCATCTTT
	ATACTAATAAATACATACTTAATGAACCCCTTATATCACAA
	(SEQ ID NO: 284)

pARBI-680:	TCAATGTATTTTTGTATAGTCTTTTGAGATTAGAGTGAAGTTCTAAAAAG	2541
SMAD2_3_	TAAGAGAACCTTTTGTGAAAATATTTTAATTGACACTACTAAGAGTTTAA
Exogenous_60	AATAGTATTGGTGGTGAAAAATCGTTAAAAGTATCTGATTTTACTTGCAA
	AATTACTGTATTTTCCCACAAGAGGAGTCCTTACAACATTCTTGTTTTTA
	GAAGGGTTTGTTTCCATCATTCATTTAAATTCATAAAGATAACGTTTTCA
	TGGGTGGAGAAGTCTATTGGGAAAGTCATAATTCGAATTTCTATCTTGCT
	TTGCAGTTTGCTTTCTATGATAAGTTGAAATTATTACTTGATGTTCAAGG
	TAGTCTCTACATCATCCTTTCAATATTTCTGCTAGGTTCGATACAAGAGG
	CTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatTTGCCATTCA
	CGCCGCCAGTIGTGAAGAGACTGCTGGGATGGAAGAAGTCAGCTGGTGGG
	TCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTG
	TGAGAAAGCAGTGAAAAGTCTGGTGAAGAAGCTAAAGAAAACAGGACGAT
	TAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGT
	GTTACCATACCAAGGTAAGTTTTGTTAGATCCCAGGTTTGATCAAATTAT
	GTCAAGGAATCTGAAGGAAAGTTACTGAATTTGTGTTCCTTTCAAGTTGC
	CTGTAAAAAGTGATGATTGAAATATGACTGTTTTTAACCTTGTATAAATT
	GTTTTTGCTAGCTGACTTGTTTTATAAATTATTTTCTTGAATAGTGAGGT
	TTAATCAAGCTAAATAAGATACTTAGATTTATTATCTTCA
	(SEQ ID NO: 285)

pARBI-681:	GGGCTCCCGCAGCACAGCCTTTCTCCGGCCCTAGCCCAAATCGCCCAGAC	2541
SOCS1_1_	CAGGCGCGGATCCCAGCCTGGCCAGCAGGCGGCGGGCGCGGGGCGGCGAG
Exogenous_61	CCGGGGCCGGACGGCTGGAGCCAGAACCGGCTGCTCTCCACGCCCCCCTC
	TCGGTGCTGCCCGGAGGCCGGACTCCGCCTCCACCGAGCCCCCACCCGCC
	GGGAAGAGCTCCGCGGAGTACAGAGCCCATTTTCTAGCTGTGTCCACTGA
	GGCTGAACGGATCCGCGCGGACTTGGTGCTCCGTGCTCGCCCCCTAGGGC
	CGGGTCCGCCGGGAGCGCCGCCCTCCGGAGTTGTCCGGCCGGCGCACACC
	TGCCCGGCCCCGCAGCGCCCCAGCTCACCTCTTTGTCTCTCCCGCAGCGC
	ACCCCCGGACGCTATGGCCCACCCCTCCGGCTGGCCCCTTCTGTAGGATG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGTAGCACAC
	AACCAGGTGGCAGCCGACAATGCAGTCTCCACAGCAGCAGAGCCCCGACG
	GCGGCCAGAACCTTCCTCCTCTTCCTCCTCCTcgcccgcggcccccgcgc
	gcccgcggccgtgccccgcggtcccggccccggCCCCCGGCGACACGCAC
	TTCCGCACATTCCGTTCGCACGCCGATTACCGGCGCATCACGCGCGCCAG
	CGCGCTCCTGGACGCCTGCGGATTCTACTGGGGGCCCCTGAGCGTGCACG
	GGGCGCACGAGCGGCTGCGCGCCGAGCCCGTGGGCACCTTCCTGGTGCGC
	GACAGCCGCCAGCGGAACTGCTTTTTCGCCCTTAGCGTGAAGATGGCCTC
	GGGACCCACGAGCATCCGCGTGCACTTTCAGGCCGGCCGCTTTCACCTGG
	ATGGCAGCCGCGAGAGCTTCGACTGCCTCTTCGAGCTGCTG
	(SEQ ID NO: 286)

pARBI-682:	GGATCCCAGCCTGGCCAGCAGGCGGCGGGCGCGGGGCGGCGAGCCGGGGC	2541
SOCS1_2_	CGGACGGCTGGAGCCAGAACCGGCTGCTCTCCACGCCCCCCTCTCGGTGC
Exogenous_62	TGCCCGGAGGCCGGACTCCGCCTCCACCGAGCCCCCACCCGCCGGGAAGA
	GCTCCGCGGAGTACAGAGCCCATTTTCTAGCTGTGTCCACTGAGGCTGAA
	CGGATCCGCGCGGACTTGGTGCTCCGTGCTCGCCCCCTAGGGCCGGGTCC
	GCCGGGAGCGCCGCCCTCCGGAGTTGTCCGGCCGGCGCACACCTGCCCGG
	CCCCGCAGCGCCCCAGCTCACCTCTTTGTCTCTCCCGCAGCGCACCCCCG
	GACGCTATGGCCCACCCCTCCGGCTGGCCCCTTCTGTAGGATGGTAGCAC
	ACAACCAGGTGGCAGCCGACAATGCAGTCTCCACAGCAGCAGAGCCCCGA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCGGCGGCCA
	GAACCTTCCTCCTCTTCCTCCTCCTcgcccgcggcccccgcgcgcccgcg
	gccgtgccccgcggtcccggccccggCCCCCGGCGACACGCACTTCCGCA
	CATTCCGTTCGCACGCCGATTACCGGCGCATCACGCGCGCCAGCGCGCTC
	CTGGACGCCTGCGGATTCTACTGGGGGCCCCTGAGCGTGCACGGGGCGCA
	CGAGCGGCTGCGCGCCGAGCCCGTGGGCACCTTCCTGGTGCGCGACAGCC
	GCCAGCGGAACTGCTTTTTCGCCCTTAGCGTGAAGATGGCCTCGGGACCC
	ACGAGCATCCGCGTGCACTTTCAGGCCGGCCGCTTTCACCTGGATGGCAG
	CCGCGAGAGCTTCGACTGCCTCTTCGAGCTGCTGGAGCACTACGTGGCGG
	CGCCGCGCCGCATGCTGGGGGCCCCGCTGCGCCAGCGCCGC
	(SEQ ID NO: 287)

pARBI-683:	CGGACTCCGCCTCCACCGAGCCCCCACCCGCCGGGAAGAGCTCCGCGGAG	2541
SOCS1_3_	TACAGAGCCCATTTTCTAGCTGTGTCCACTGAGGCTGAACGGATCCGCGC
Exogenous_63	GGACTTGGTGCTCCGTGCTCGCCCCCTAGGGCCGGGTCCGCCGGGAGCGC
	CGCCCTCCGGAGTTGTCCGGCCGGCGCACACCTGCCCGGCCCCGCAGCGC
	CCCAGCTCACCTCTTTGTCTCTCCCGCAGCGCACCCCCGGACGCTATGGC
	CCACCCCTCCGGCTGGCCCCTTCTGTAGGATGGTAGCACACAACCAGGTG
	GCAGCCGACAATGCAGTCTCCACAGCAGCAGAGCCCCGACGGCGGCCAGA
	ACCTTCCTCCTCTTCCTCCTCCTcgcccgcggcccccgcgcgcccgcggc
	cgtgccccgcggtcccggccccggCCCCCGGCGACACGCACTTCCGCACA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTTCCGTTCG
	CACGCCGATTACCGGCGCATCACGCGCGCCAGCGCGCTCCTGGACGCCTG
	CGGATTCTACTGGGGGCCCCTGAGCGTGCACGGGGCGCACGAGCGGCTGC
	GCGCCGAGCCCGTGGGCACCTTCCTGGTGCGCGACAGCCGCCAGCGGAAC
	TGCTTTTTCGCCCTTAGCGTGAAGATGGCCTCGGGACCCACGAGCATCCG
	CGTGCACTTTCAGGCCGGCCGCTTTCACCTGGATGGCAGCCGCGAGAGCT
	TCGACTGCCTCTTCGAGCTGCTGGAGCACTACGTGGCGGCGCCGCGCCGC
	ATGCTGGGGGCCCCGCTGCGCCAGCGCCGCGTGCGGCCGCTGCAGGAGCT
	GTGCCGCCAGCGCATCGTGGCCACCGTGGGCCGCGAGAACCTGGCTCGCA
	TCCCCCTCAACCCCGTCCTCCGCGACTACCTGAGCTCCTTC
	(SEQ ID NO: 288)

pARBI-684:	GGCAGACAAACAGTTAAAACAGAGGAGTGGGGTAAGTGATGACCTAACCC	2541
SRP14_1_	AGCCCCGCTGCTCTAGTTTTGTTAAACACCTCATCTGCTATCACGGTCTG
Exogenous_64	GCGAAACCCTGGAGAAACTATTATTTCCACGACGGAAACATGTAATATCG
	AAGCACGTTAAATTCCACTCAAAGTGGCGGCGTCTGGGATCCCTGACAAA
	GAGCCCTGGGCTGCTTGGGGCCCATTGTTACCAGAAGCAACCTAGGCGGC
	TCAGTGCTGGGGACTGAGCCAGCTACAATCCCTACTATTTTCCGGGCCCG
	AAGCCCCGAATGTGCTCAGTACAGGGTGGGGAAAGGTAGAGGAAGGCGGC
	GGTCCGCGGCAGACAGACTCCGGTGGCTCCCAGACACCGGGAACCCAGGG
	AGCATCGCCCGGCTCCCCTCCCGCTGCTTACACTTCTTCAAGGTGATATA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGACGCTGCC
	CGACGTCCGGCACTTCTGGAAAAGTCTGGTCAGCTCCGTCAGGAACTGGA
	AAACAACAGGCCCAGCCCCGTTAGCCAGCCCCAAATCCTCGTCCTGCCGC
	GTCAAGGCCCTGGTCCTCCTGCAGGAGGCACAGGTCTCGAGTAACGCCTG
	AGCCGCCCCCTTCCCTCGGCCGGCCAGGCCTAGCCATACCTGCTCGCTCT
	CCAACAACACCATCGCGGCGACGCTGGCTCGACTCCCTCCGCTTAAGCCC
	CTAGCAGTGAGAGCCGGAAGTTCGGCCTAGGCTGGGCGGGACTTCCGCTA
	CTAGACTTCCATTGTCTTCCACCAATCTCTTCTCTTCCACCAATCCCGGC
	CTGCGCCCTCCCCCCTCCCCGCCCGCCTAGCGCCCGCGCCCTGGGACGTC
	CGGGGGCCTGTGACCCGGAGGCGCTGGGGCTGTCCTGGGTC
	(SEQ ID NO: 289)

pARBI-685:	GTCTGTCTGCCGCGGACCGCCGCCTTCCTCTACCTTTCCCCACCCTGTAC	2541
SRP14_2_	TGAGCACATTCGGGGCTTCGGGCCCGGAAAATAGTAGGGATTGTAGCTGG
Exogenous_	CTCAGTCCCCAGCACTGAGCCGCCTAGGTTGCTTCTGGTAACAATGGGCC
65_66	CCAAGCAGCCCAGGGCTCTTTGTCAGGGATCCCAGACGCCGCCACTTTGA
	GTGGAATTTAACGTGCTTCGATATTACATGTTTCCGTCGTGGAAATAATA
	GTTTCTCCAGGGTTTCGCCAGACCGTGATAGCAGATGAGGTGTTTAACAA
	AACTAGAGCAGCGGGGCTGGGTTAGGTCATCACTTACCCCACTCCTCTGT
	TTTAACTGTTTGTCTGCCGCTCAGCCACGTACGCGGCCGTGTTCACCAGG
	ATGCATTTTTTCCTTCAGATGACGGTCGAACCAAACCCATTCCAAAGAAG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGGTACTGTG
	GAGGGCTTTGAGCCCGCAGACAACAAGTGTCTGTTAAGAGCTACCGATGG
	GAAGAAGAAGATCAGCACTGTGGTGAGCTTAATTTCTAAGGCTGTCTTTT
	GAAATGTAAAGACTTGAACTTAACAGAGGATGGGGCGTTTCTGAACCAGG
	CTTTTATTTGTTTTTCCCTTTTGCCCTGTGTGGCTATTTTTGAGACCAGG
	ACCTTCCTATACTTTAGTAGTGGAAACCTCAAGAATAAAATAAGAAGGTA
	GAGGTCAGACAGTCGTTAGTTCTGCTAAAGCTCTTGTGGAAATGAAAGTA
	GCATATTGGTCCTTATTCGTAGTACTGTAAGGAGCAGCTGGCATAAATAT
	TTGATTCCTTAGCCCCTTACTGTGCTGGGCCTTCAATAAGCAGTTTCTTG
	GTACCAGGTGATGCTATTATTTCCTTATCTTTGTGGTTCAC
	(SEQ ID NO: 290)

pARBI-686:	CCCACGTCAGTGAGTGCTCACAAGTCTGTGAGGTAGGCGGCGCCACAGAG	2541
SRSF9_1_	AGAAACTGAGGCGCGGGAGCCCAAGCCACTTGTCCAGCGCCTCAGCCGAG
Exogenous_67	CGCGAACCGCGCTCGGGGATGGCATCCACACGGCCCGGCCCCAGGCTCTC
	CCTGTCAGCGCCCGAAGGCCCTTCGCACCTCCAGGGGGCGCCGGCCTGCG
	CGCACGCGCAATGGTCGCAGCCGCGTTCTCTTTAAGAGGACTCCTTTTGC
	CTCCGCCGACCCCTTCGCTTCCGCTCCGCGTTCCCACAATGCAGTGCGGC
	TGAGCGCCTCGGAGCCCGCGGGGACGCTGCGGGGGGACCCGTGCTGAggc
	ggcggcggcgacgtgggctgcggcgggcccgcggcgtcgggcggtgcgga
	tgtcgggctgggcggacgagcgcggcggcgAGGGCGACGGGCGCATCTAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatGTGGGGAACC
	TTCCGACCGACGTGCGCGAGAAGGACTTGGAGGACCTGTTCTACAAGTAC
	GGCCGCATCCGCGAGATCGAGCTCAAGAACCGGCACGGCCTCGTGCCCTT
	CGCCTTCGTGCGCTTCGAGGACCCCCGGTGAGGcccccgcgcccctgccc
	tctcctcctcggtgcctgaggcccccgccttccctgctgtcccctccccc
	agggctcccctccccccggcctcccctccccccgcctccgcgcagacccc
	tcaCGGCGCCCCCTCACGGGTGGAGGATGAGGCAGCCTCTCCTCGCAGGC
	CCGGGCCGTCCTTCGCGCCGTCGTCACTTCCTTTATTTTTATTATTCCAA
	TATTTTACTTAGAAACCCAAAAGCTGAGCCTTTGGAGGGCCCAAGCCCGC
	CTGCACCGGCCTCGGGGGGTCCAAATGAGCCTTGTCCGCC
	(SEQ ID NO: 291)

pARBI-687:	TGTGGTGTGCTTTTCGAGAAAATGCTCACGAAGATTAGAAAAACACTGAT	2541
SRSF9_2_	GGTTTATTGGCAAAATCAATAATCTGTCAGCAGTTGATTCttttttttCT
Exogenous_68	CTGAATTAGCCCTCTTATGAGTAATCTGTTTGCTCATTCATTATAATTTC
	ATACCTCTAAAACTGCGTGTGACAGCTGTAAAGGTTAATTCCAGTATCAT
	GAAACGTCTCCAAACCAAAGCAGAAGTGCTTCAGGATCCTGATTTGTGTG
	TTTTTTTCTTCACTCTAGGTTTCCCTTTTATGCTTACTACTCATGCCCCT
	CACTTGGAAAGTCACTTGGCCTCCTGAACAGCACTAACTCCAAACGtttt
	ttttgttgttgttgttttttttAGAGATGCAGAGGATGCTATTTATGGAA
	GAAATGGTTATGATTATGGCCAGTGTCGGCTTCGTGTGGAGTTCCCCAGG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggggggtggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatACTTATGGAG
	GTCGGGGTGGGTGGCCCCGTGGTGGGAGGAATGGGCCTCCTACAAGAAGA
	TCTGATTTCCGAGTTCTTGTTTCAGGTATGTTCCTTTCAAACAGaatgag
	atgatacatgtaaaatacttaacacagagtctgtcttccaagaaatgata
	gctgttattcttCAGTGCATGGGACACGGGGGCTTTCTTTTCAATAGCCT
	GTGTGAAGCCTTGCCCTGGATTGCCAATGAGGAAAGTATCCTGCAAATGA
	AATTGCGCTGGGAGTGCAGCCTTGGAAGAACATAACCATATTTCTTGTAA
	AGGAGTTTTCTAGTGGTGAGAAGGAAAGATGATGGGAAAACTTGAGCTAC
	AATTCTAAAGATGCTTCTTTTGGAATATACTTGGCATCAGACATGGTAGA
	AAGGCATTCAAGGAGCCAGATTTGAACAACTTACCCAGCC
	(SEQ ID NO: 292)

pARBI-688:	GATGGCATCCACACGGCCCGGCCCCAGGCTCTCCCTGTCAGCGCCCGAAG	2541
SRSF9_3_	GCCCTTCGCACCTCCAGGGGGCGCCGGCCTGCGCGCACGCGCAATGGTCG
Exogenous_69	CAGCCGCGTTCTCTTTAAGAGGACTCCTTTTGCCTCCGCCGACCCCTTCG
	CTTCCGCTCCGCGTTCCCACAATGCAGTGCGGCTGAGCGCCTCGGAGCCC
	GCGGGGACGCTGCGGGGGGACCCGTGCTGAggcggcggcggcgacgtggg
	ctgcggcgggcccgcggcgtcgggcggtgcggatgtcgggctgggcggac
	gagcgcggcggcgAGGGCGACGGGCGCATCTACGTGGGGAACCTTCCGAC
	CGACGTGCGCGAGAAGGACTTGGAGGACCTGTTCTACAAGTACGGCCGCA
	TCCGCGAGATCGAGCTCAAGAACCGGCACGGCCTCGTGCCCTTCGCCTTC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGTGCGCTTC
	GAGGACCCCCGGTGAGGcccccgcgcccctgccctctcctcctcggtgcc
	tgaggcccccgccttccctgctgtcccctcccccagggctcccctccccc
	cggcctcccctccccccgcctccgcgcagacccctcaCGGCGCCCCCTCA
	CGGGTGGAGGATGAGGCAGCCTCTCCTCGCAGGCCCGGGCCGTCCTTCGC
	GCCGTCGTCACTTCCTTTATTTTTATTATTCCAATATTTTACTTAGAAAC
	CCAAAAGCTGAGCCTTTGGAGGGCCCAAGCCCGCCTGCACCGGCCTCGGG
	GGGTCCAAATGAGCCTTGTCCGCCTCCTGCCTGGGGCAGCACCGTAGGGG
	GAAGCGGCCGCGGGGCAGCGCGGGGGTCGCCGTTCGCCCTTCCCGCTCGC
	CTCTCCCCCGGCCCGTGCTCGCCGTGGCTGGAGAGCAAGCT
	(SEQ ID NO: 293)

pARBI-689:	GTAACTGACTAGCCTTAGTAGACTGTGGTTTCCAGGTTTATTCAGAAGTA	2541
SUB1_1_	GCAAGATCCCTCCAtttttttttCTACCAAAGAAATCGTATGTGGGATCC
Exogenous_70	CAAACCACAAAATAACCGTTCCTGTGGTTAATACTACTATAATGCCTGAA
	GTGTCTTTTGGGATCCTGAGAACAGAGTTTGAAAACATTACTAGACAGAA
	GGATTGGTTAGATTCATAGTTTTGTTGTTGAGTGAAACTTGCTTATGTAT
	ATATTTATGATATTTTGGATGTAGTCTTTTGATTGTTTAAATCTTAAAAA
	GTAATGGGATCTTTTGACACTGGGGTATGTTTTATTTTTATGTGTGCAAA
	TTTTAACCATATTCTTTTCTAGTTAAAGAGGAAAAAGCAAGTTGCTCCAG
	AAAAACCTGTAAAGAAACAAAAGACAGGTGAGACTTCGAGAGCCCTGTCA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatTCTTCTAAAC
	AGAGCAGCAGCAGCAGAGATGATAACATGTTTCAGGTAAAGTTGGCTAtt
	ttttttttttttttttttgacatggagtcatgctctgtcacccaggctgg
	agtgcagtggcgccatctcggctcactgcaacctcagcctcctgagttca
	agcagttctctgcctcagcctcccgagtagctaggattacaggcatccgc
	caccagacctggctaatttttgtatttttagtagagatggggtttcacca
	tcttggccaggctggtcttgaactcctgaccttgtgatccaactgcctca
	gcctccaaaagtgctgggtttacaggtgtgagccaccatgccttgccAAA
	GTTGGCTGTTTCTTTAGATTCAGAGGAATTATTATCTGGCTTGATCTGAA
	GAATGTTAAAAGTACTATGATCTGATAATTGCCTAATATG
	(SEQ ID NO: 294)

pARBI-690:	ATAAATAAACATATCCTGGAAATGGAATAAGTTGGTTATATTCTTTTTAA	2541
SUB1_2_	TTAGTATATCTGCTTCGTAAAATAAGTAACTGACTAGCCTTAGTAGACTG
Exogenous_71	TGGTTTCCAGGTTTATTCAGAAGTAGCAAGATCCCTCCATTTTTTTTTCT
	ACCAAAGAAATCGTATGTGGGATCCCAAACCACAAAATAACCGTTCCTGT
	GGTTAATACTACTATAATGCCTGAAGTGTCTTTTGGGATCCTGAGAACAG
	AGTTTGAAAACATTACTAGACAGAAGGATTGGTTAGATTCATAGTTTTGT
	TGTTGAGTGAAACTTGCTTATGTATATATTTATGATATTTTGGATGTAGT
	CTTTTGATTGTTTAAATCTTAAAAAGTAATGGGATCTTTTGACACTGGGG
	TATGTTTTATTTTTATGTGTGCAAATTTTAACCATATTCTTTTCTAGTTA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatAAGAGGAAA
	AAGCAAGTTGCTCCAGAAAAACCTGTAAAGAAACAAAAGACAGGTGAGAC
	TTCGAGAGCCCTGTCATCTTCTAAACAGAGCAGCAGCAGCAGAGATGATA
	ACATGTTTCAGGTAAAGTTGGCTATTTTTTTTTTTTTTTTTTTTGACATG
	GAGTCATGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCCATCTCGGCTC
	ACTGCAACCTCAGCCTCCTGAGTTCAAGCAGTTCTCTGCCTCAGCCTCCC
	GAGTAGCTAGGATTACAGGCATCCGCCACCAGACCTGGCTAATTTTTGTA
	TTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCAGGCTGGTCTTGAACT
	CCTGACCTTGTGATCCAACTGCCTCAGCCTCCAAAAGTGCTGGGTTTACA
	GGTGTGAGCCACCATGCCTTGCCAAAGTTGGCTGTTTCTTT
	(SEQ ID NO: 295)

pARBI-691:	AATTAGTATATCTGCTTCGTAAAATAAGTAACTGACTAGCCTTAGTAGAC	2541
SUB1_3_	TGTGGTTTCCAGGTTTATTCAGAAGTAGCAAGATCCCTCCATTTTTTTTT
Exogenous_72	CTACCAAAGAAATCGTATGTGGGATCCCAAACCACAAAATAACCGTTCCT
	GTGGTTAATACTACTATAATGCCTGAAGTGTCTTTTGGGATCCTGAGAAC
	AGAGTTTGAAAACATTACTAGACAGAAGGATTGGTTAGATTCATAGTTTT
	GTTGTTGAGTGAAACTTGCTTATGTATATATTTATGATATTTTGGATGTA
	GTCTTTTGATTGTTTAAATCTTAAAAAGTAATGGGATCTTTTGACACTGG
	GGTATGTTTTATTTTTATGTGTGCAAATTTTAACCATATTCTTTTCTAGT
	TAAAGAGGAAAAAGCAAGTTGCTCCAGAAAAACCTGTAAAGAAACAAAAG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatACAGGTGAG
	ACTTCGAGAGCCCTGTCATCTTCTAAACAGAGCAGCAGCAGCAGAGATGA
	TAACATGTTTCAGGTAAAGTTGGCTATTTTTTTTTTTTTTTTTTTTGACA
	TGGAGTCATGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCCATCTCGGC
	TCACTGCAACCTCAGCCTCCTGAGTTCAAGCAGTTCTCTGCCTCAGCCTC
	CCGAGTAGCTAGGATTACAGGCATCCGCCACCAGACCTGGCTAATTTTTG
	TATTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCAGGCTGGTCTTGAA
	CTCCTGACCTTGTGATCCAACTGCCTCAGCCTCCAAAAGTGCTGGGTTTA
	CAGGTGTGAGCCACCATGCCTTGCCAAAGTTGGCTGTTTCTTTAGATTCA
	GAGGAATTATTATCTGGCTTGATCTGAAGAATGTTAAAAGT
	(SEQ ID NO: 296)

pARBI-692:	CACATTTTAATTTTTGTTTCCATGCTCTTTAGAATTCAACTAGAGGGCAG	2541
TET2_1_	CCTTGTGGATGGCCCCGAAGCAAGCCTGATGGAACAGGATAGAACCAACC
Exogenous_73	ATGTTGAGGGCAACAGACTAAGTCCATTCCTGATACCATCACCTCCCATT
	TGCCAGACAGAACCTCTGGCTACAAAGCTCCAGAATGGAAGCCCACTGCC
	TGAGAGAGCTCATCCAGAAGTAAATGGAGACACCAAGTGGCACTCTTTCA
	AAAGTTATTATGGAATACCCTGTATGAAGGGAAGCCAGAATAGTCGTGTG
	AGTCCTGACTTTACACAAGAAAGTAGAGGGTATTCCAAGTGTTTGCAAAA
	TGGAGGAATAAAACGCACAGTTAGTGAACCTTCTCTCTCTGGGCTCCTTC
	AGATCAAGAAATTGAAACAAGACCAAAAGGCTAATGGAGAAAGACGTAAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTTCGGGGTA
	AGCCAAGAAAGAAATCCAGGTGAAAGCAGTCAACCAAATGTCTCCGATTT
	GAGTGATAAGAAAGAATCTGTGAGTTCTGTAGCCCAAGAAAATGCAGTTA
	AAGATTTCACCAGTTTTTCAACACATAACTGCAGTGGGCCTGAAAATCCA
	GAGCTTCAGATTCTGAATGAGCAGGAGGGGAAAAGTGCTAATTACCATGA
	CAAGAACATTGTATTACTTAAAAACAAGGCAGTGCTAATGCCTAATGGTG
	CTACAGTTTCTGCCTCTTCCGTGGAACACACACATGGTGAACTCCTGGAA
	AAAACACTGTCTCAATATTATCCAGATTGTGTTTCCATTGCGGTGCAGAA
	AACCACATCTCACATAAATGCCATTAACAGTCAGGCTACTAATGAGTTGT
	CCTGTGAGATCACTCACCCATCGCATACCTCAGGGCAGATC
	(SEQ ID NO: 297)

pARBI-693:	AATGGAGAAAGACGTAACTTCGGGGTAAGCCAAGAAAGAAATCCAGGTGA	2541
TET2_2_	AAGCAGTCAACCAAATGTCTCCGATTTGAGTGATAAGAAAGAATCTGTGA
Exogenous_74	GTTCTGTAGCCCAAGAAAATGCAGTTAAAGATTTCACCAGTTTTTCAACA
	CATAACTGCAGTGGGCCTGAAAATCCAGAGCTTCAGATTCTGAATGAGCA
	GGAGGGGAAAAGTGCTAATTACCATGACAAGAACATTGTATTACTTAAAA
	ACAAGGCAGTGCTAATGCCTAATGGTGCTACAGTTTCTGCCTCTTCCGTG
	GAACACACACATGGTGAACTCCTGGAAAAAACACTGTCTCAATATTATCC
	AGATTGTGTTTCCATTGCGGTGCAGAAAACCACATCTCACATAAATGCCA
	TTAACAGTCAGGCTACTAATGAGTTGTCCTGTGAGATCACTCACCCATCG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatCATACCTCA
	GGGCAGATCAATTCCGCACAGACCTCTAACTCTGAGCTGCCTCCAAAGCC
	AGCTGCAGTGGTGAGTGAGGCCTGTGATGCTGATGATGCTGATAATGCCA
	GTAAACTAGCTGCAATGCTAAATACCTGTTCCTTTCAGAAACCAGAACAA
	CTACAACAACAAAAATCAGTTTTTGAGATATGCCCATCTCCTGCAGAAAA
	TAACATCCAGGGAACCACAAAGCTAGCGTCTGGTGAAGAATTCTGTTCAG
	GTTCCAGCAGCAATTTGCAAGCTCCTGGTGGCAGCTCTGAACGGTATTTA
	AAACAAAATGAAATGAATGGTGCTTACTTCAAGCAAAGCTCAGTGTTCAC
	TAAGGATTCCTTTTCTGCCACTACCACACCACCACCACCATCACAATTGC
	TTCTTTCTCCCCCTCCTCCTCTTCCACAGGTTCCTCAGCTT
	(SEQ ID NO: 298)

pARBI-694:	GGAAAAAGCACTCTGAATGGTGGAGTTTTAGAAGAACACCACCACTACCC	2541
TET2_3_	CAACCAAAGTAACACAACACTTTTAAGGGAAGTGAAAATAGAGGGTAAAC
Exogenous_75	CTGAGGCACCACCTTCCCAGAGTCCTAATCCATCTACACATGTATGCAGC
	CCTTCTCCGATGCTTTCTGAAAGGCCTCAGAATAATTGTGTGAACAGGAA
	TGACATACAGACTGCAGGGACAATGACTGTTCCATTGTGTTCTGAGAAAA
	CAAGACCAATGTCAGAACACCTCAAGCATAACCCACCAATTTTTGGTAGC
	AGTGGAGAGCTACAGGACAACTGCCAGCAGTTGATGAGAAACAAAGAGCA
	AGAGATTCTGAAGGGTCGAGACAAGGAGCAAACACGAGATCTTGTGCCCC
	CAACACAGCACTATCTGAAACCAGGATGGATTGAATTGAAGGCCCCTCGT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatTTTCACCAAG
	CGGAATCCCATCTAAAACGTAATGAGGCATCACTGCCATCAATTCTTCAG
	TATCAACCCAATCTCTCCAATCAAATGACCTCCAAACAATACACTGGAAA
	TTCCAACATGCCTGGGGGGCTCCCAAGGCAAGCTTACACCCAGAAAACAA
	CACAGCTGGAGCACAAGTCACAAATGTACCAAGTTGAAATGAATCAAGGG
	CAGTCCCAAGGTACAGTGGACCAACATCTCCAGTTCCAAAAACCCTCACA
	CCAGGTGCACTTCTCCAAAACAGACCATTTACCAAAAGCTCATGTGCAGT
	CACTGTGTGGCACTAGATTTCATTTTCAACAAAGAGCAGATTCCCAAACT
	GAAAAACTTATGTCCCCAGTGTTGAAACAGCACTTGAATCAACAGGCTTC
	AGAGACTGAGCCATTTTCAAACTCACACCTTTTGCAACAT
	(SEQ ID NO: 299)

pARBI-695:	AAAGGGAGGTTGAGATGGGCTGAGGTCTTCTAGGAGGCGGGGAGGGAGTG	2541
TIGIT_1_	CAGCCTTGACAAGCCTCCCTGTGGGCGAGGTGTAAAGAGGGGCAGAAGTC
Exogenous_76	AGCTCTGGAAGCATAGGGCAGTGGGTGGGGAGGAGATGGGCTGGGCTGGG
	CTGGAGTAGAGATGTGTGGAGAAGGGTGAGAAGACTGGAAAGACAACCTG
	AATGGGGGACTGGGAGCCTTGAATAACAGGCATGGAGAGGAGCGTCTCTT
	GAAATGGAAGAAACAGGAAATAATTACAGCCTCTATGGAGGAGCAACAGG
	ATGGACTGGAGAAACTATCATTCCAAAATCCAGTTGGGGCCTCAAAGGCC
	CTTAGAATTTTTCTAGGAAGGTTGAAGGCCAGCTGCTGACCCAGGACTCA
	CATGTGCTTCGTCCTCTTCCCTAGGAATGATGACAGGCACAATAGAAACA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatACGGGGAAC
	ATTTCTGCAGAGAAAGGTGGCTCTATCATCTTACAATGTCACCTCTCCTC
	CACCACGGCACAAGTGACCCAGGTCAACTGGGAGCAGCAGGACCAGCTTC
	TGGCCATTTGTAATGCTGACTTGGGGTGGCACATCTCCCCATCCTTCAAG
	GATCGAGTGGCCCCAGGTCCCGGCCTGGGCCTCACCCTCCAGTCGCTGAC
	CGTGAACGATACAGGGGAGTACTTCTGCATCTATCACACCTACCCTGATG
	GGACGTACACTGGGAGAATCTTCCTGGAGGTCCTAGAAAGCTCAGGTATT
	CCTGCTGGAGCAAGTTGGTGGATAAACCTCTCCCTCTAGCATAGAAAATG
	CAATCCTGAAACACTGCACAGCAGGGCTTCTCAATTCGGGATCACATTTG
	AATCACCTGAGGAGATTTTAAATCATACTGATGCCGAGGCC
	(SEQ ID NO: 300)

pARBI-696:	GAGGAGATGGGCTGGGCTGGGCTGGAGTAGAGATGTGTGGAGAAGGGTGA	2541
TIGIT_2_	GAAGACTGGAAAGACAACCTGAATGGGGGACTGGGAGCCTTGAATAACAG
Exogenous_77	GCATGGAGAGGAGCGTCTCTTGAAATGGAAGAAACAGGAAATAATTACAG
	CCTCTATGGAGGAGCAACAGGATGGACTGGAGAAACTATCATTCCAAAAT
	CCAGTTGGGGCCTCAAAGGCCCTTAGAATTTTTCTAGGAAGGTTGAAGGC
	CAGCTGCTGACCCAGGACTCACATGTGCTTCGTCCTCTTCCCTAGGAATG
	ATGACAGGCACAATAGAAACAACGGGGAACATTTCTGCAGAGAAAGGTGG
	CTCTATCATCTTACAATGTCACCTCTCCTCCACCACGGCACAAGTGACCC
	AGGTCAACTGGGAGCAGCAGGACCAGCTTCTGGCCATTTGTAATGCTGAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTTGGGGTGG
	CACATCTCCCCATCCTTCAAGGATCGAGTGGCCCCAGGTCCCGGCCTGGG
	CCTCACCCTCCAGTCGCTGACCGTGAACGATACAGGGGAGTACTTCTGCA
	TCTATCACACCTACCCTGATGGGACGTACACTGGGAGAATCTTCCTGGAG
	GTCCTAGAAAGCTCAGGTATTCCTGCTGGAGCAAGTTGGTGGATAAACCT
	CTCCCTCTAGCATAGAAAATGCAATCCTGAAACACTGCACAGCAGGGCTT
	CTCAATTCGGGATCACATTTGAATCACCTGAGGAGATTTTAAATCATACT
	GATGCCGAGGCCTCACCCAGACCAATTCAATCAGAATCCCTAATAGCAGA
	GCTAAACAAGGGTAAGGTCTAAAAGCATTTCCAGGTGATTCTAATGGGCA
	GCCAATACTGAGAACCACTGTTCTTATGTAAGAAGCACATC
	(SEQ ID NO: 301)

pARBI-697:	CCTCCCTGTGGGCGAGGTGTAAAGAGGGGCAGAAGTCAGCTCTGGAAGCA	2541
TIGIT_3_	TAGGGCAGTGGGTGGGGAGGAGATGGGCTGGGCTGGGCTGGAGTAGAGAT
Exogenous_78	GTGTGGAGAAGGGTGAGAAGACTGGAAAGACAACCTGAATGGGGGACTGG
	GAGCCTTGAATAACAGGCATGGAGAGGAGCGTCTCTTGAAATGGAAGAAA
	CAGGAAATAATTACAGCCTCTATGGAGGAGCAACAGGATGGACTGGAGAA
	ACTATCATTCCAAAATCCAGTTGGGGCCTCAAAGGCCCTTAGAATTTTTC
	TAGGAAGGTTGAAGGCCAGCTGCTGACCCAGGACTCACATGTGCTTCGTC
	CTCTTCCCTAGGAATGATGACAGGCACAATAGAAACAACGGGGAACATTT
	CTGCAGAGAAAGGTGGCTCTATCATCTTACAATGTCACCTCTCCTCCACC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggggggcaggacagcaagggggaggattgggaagacaatagca
	ggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGGT
	GCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGGG
	GGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTAA
	ACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGGG
	GGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCAA
	CGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCTC
	CTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAGT
	CGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCGT
	CTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTCC
	CTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCTG
	CTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACAG
	ATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccacc
	ATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGGT
	CGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAGG
	GCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCACC
	ACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCTA
	CGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGACT
	TCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTTC
	TTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGGG
	CGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAGG
	ACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAAC
	GTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCAA
	GATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTACC
	AGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCAC
	TACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCGA
	TCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGCA
	TGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaaa
	taaagcaatagcatcacaaatttcacaaataaagcatttttttcactgca
	ttctagttgtggtttgtccaaactcatcaatgtatcttatACGGCACAAG
	TGACCCAGGTCAACTGGGAGCAGCAGGACCAGCTTCTGGCCATTTGTAAT
	GCTGACTTGGGGTGGCACATCTCCCCATCCTTCAAGGATCGAGTGGCCCC
	AGGTCCCGGCCTGGGCCTCACCCTCCAGTCGCTGACCGTGAACGATACAG
	GGGAGTACTTCTGCATCTATCACACCTACCCTGATGGGACGTACACTGGG
	AGAATCTTCCTGGAGGTCCTAGAAAGCTCAGGTATTCCTGCTGGAGCAAG
	TTGGTGGATAAACCTCTCCCTCTAGCATAGAAAATGCAATCCTGAAACAC
	TGCACAGCAGGGCTTCTCAATTCGGGATCACATTTGAATCACCTGAGGAG
	ATTTTAAATCATACTGATGCCGAGGCCTCACCCAGACCAATTCAATCAGA
	ATCCCTAATAGCAGAGCTAAACAAGGGTAAGGTCTAAAAG
	(SEQ ID NO: 302)

pARBI-698:	TAATGCCCAGCCTAAGTTGGGGAGACCACTCCAGATTCCAAGATGTACAG	2541
TRAC_1_	TTTGCTTTGCTGGGCCTTTTTCCCATGCCTGCCTTTACTCTGCCAGAGTT
Exogenous_79	ATATTGCTGGGGTTTTGAAGAAGATCCTATTAAATAAAAGAATAAGCAGT
	ATTATTAAGTAGCCCTGCATTTCAGGTTTCCTTGAGTGGCAGGCCAGGCC
	TGGCCGTGAACGTTCACTGAAATCATGGCCTCTTGGCCAAGATTGATAGC
	TTGTGCCTGTCCCTGAGTCCCAGTCCATCACGAGCAGCTGGTTTCTAAGA
	TGCTATTTCCCGTATAAAGCATGAGACCGTGACTTGCCAGCCCCACAGAG
	CCCCGCCCTTGTCCATCACTGGCATCTGGACTCCAGCCTGGGTTGGGGCA
	AAGAGGGAAATGAGATCATGTCCTAACCCTGATCCTCTTGTCCCACAGAT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatATCCAGAAC
	CCTGACCCTGCCGTGTACCAGCTGAGAGACTCTAAATCCAGTGACAAGTC
	TGTCTGCCTATTCACCGATTTTGATTCTCAAACAAATGTGTCACAAAGTA
	AGGATTCTGATGTGTATATCACAGACAAAACTGTGCTAGACATGAGGTCT
	ATGGACTTCAAGAGCAACAGTGCTGTGGCCTGGAGCAACAAATCTGACTT
	TGCATGTGCAAACGCCTTCAACAACAGCATTATTCCAGAAGACACCTTCT
	TCCCCAGCCCAGGTAAGGGCAGCTTTGGTGCCTTCGCAGGCTGTTTCCTT
	GCTTCAGGAATGGCCAGGTTCTGCCCAGAGCTCTGGTCAATGATGTCTAA
	AACTCCTCTGATTGGTGGTCTCGGCCTTATCCATTGCCACCAAAACCCTC
	TTTTTACTAAGAAACAGTGAGCCTTGTTCTGGCAGTCCAGA
	(SEQ ID NO: 303)

pARBI-699:	GATTCCAAGATGTACAGTTTGCTTTGCTGGGCCTTTTTCCCATGCCTGCC	2541
TRAC_2_	TTTACTCTGCCAGAGTTATATTGCTGGGGTTTTGAAGAAGATCCTATTAA
Exogenous_80	ATAAAAGAATAAGCAGTATTATTAAGTAGCCCTGCATTTCAGGTTTCCTT
	GAGTGGCAGGCCAGGCCTGGCCGTGAACGTTCACTGAAATCATGGCCTCT
	TGGCCAAGATTGATAGCTTGTGCCTGTCCCTGAGTCCCAGTCCATCACGA
	GCAGCTGGTTTCTAAGATGCTATTTCCCGTATAAAGCATGAGACCGTGAC
	TTGCCAGCCCCACAGAGCCCCGCCCTTGTCCATCACTGGCATCTGGACTC
	CAGCCTGGGTTGGGGCAAAGAGGGAAATGAGATCATGTCCTAACCCTGAT
	CCTCTTGTCCCACAGATATCCAGAACCCTGACCCTGCCGTGTACCAGCTG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatAGAGACTCT
	AAATCCAGTGACAAGTCTGTCTGCCTATTCACCGATTTTGATTCTCAAAC
	AAATGTGTCACAAAGTAAGGATTCTGATGTGTATATCACAGACAAAACTG
	TGCTAGACATGAGGTCTATGGACTTCAAGAGCAACAGTGCTGTGGCCTGG
	AGCAACAAATCTGACTTTGCATGTGCAAACGCCTTCAACAACAGCATTAT
	TCCAGAAGACACCTTCTTCCCCAGCCCAGGTAAGGGCAGCTTTGGTGCCT
	TCGCAGGCTGTTTCCTTGCTTCAGGAATGGCCAGGTTCTGCCCAGAGCTC
	TGGTCAATGATGTCTAAAACTCCTCTGATTGGTGGTCTCGGCCTTATCCA
	TTGCCACCAAAACCCTCTTTTTACTAAGAAACAGTGAGCCTTGTTCTGGC
	AGTCCAGAGAATGACACGGGAAAAAAGCAGATGAAGAGAAG
	(SEQ ID NO: 304)

pARBI-700:	TTCCTGTGGTAGCGGAACTCACTAAGGGGCCCATCTGGACCCGAGGTATT	2541
TRAC_3_	GTGATGATAAATTCTGAGCACCTACCCCATCCCCAGAAGGGCTCAGAAAT
Exogenous_81	AAAATAAGAGCCAAGTCTAGTCGGTGTTTCCTGTCTTGAAACACAATACT
	GTTGGCCCTGGAAGAATGCACAGAATCTGTTTGTAAGGGGATATGCACAG
	AAGCTGCAAGGGACAGGAGGTGCAGGAGCTGCAGGCCTCCCCCACCCAGC
	CTGCTCTGCCTTGGGGAAAACCGTGGGTGTGTCCTGCAGGCCATGCAGGC
	CTGGGACATGCAAGCCCATAACCGCTGTGGCCTCTTGGTTTTACAGATAC
	GAACCTAAACTTTCAAAACCTGTCAGTGATTGGGTTCCGAATCCTCCTCC
	TGAAAGTGGCCGGGTTTAATCTGCTCATGACGCTGCGGCTGTGGTCCAGC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTGAGGTGAG
	GGGCCTTGAAGCTGGGAGTGGGGTTTAGGGACGCGGGTCTCTGGGTGCAT
	CCTAAGCTCTGAGAGCAAACCTCCCTGCAGGGTCTTGCTTTTAAGTCCAA
	AGCCTGAGCCCACCAAACTCTCCTACTTCTTCCTGTTACAAATTCCTCTT
	GTGCAATAATAATGGCCTGAAACGCTGTAAAATATCCTCATTTCAGCCGC
	CTCAGTTGCACTTCTCCCCTATGAGGTAGGAAGAACAGTTGTTTAGAAAC
	GAAGAAACTGAGGCCCCACAGCTAATGAGTGGAGGAAGAGAGACACTTGT
	GTACACCACATGCCTTGTGTTGTACTTCTCTCACCGTGTAACCTCCTCAT
	GTCCTCTCTCCCCAGTACGGCTCTCTTAGCTCAGTAGAAAGAAGACATTA
	CACTCATATTACACCCCAATCCTGGCTAGAGTCTCCGCACC
	(SEQ ID NO: 305)

pARBI-701:	ATTATTAAGTAGCCCTGCATTTCAGGTTTCCTTGAGTGGCAGGCCAGGCC	2541
TRAC_4_	TGGCCGTGAACGTTCACTGAAATCATGGCCTCTTGGCCAAGATTGATAGC
Exogenous_82	TTGTGCCTGTCCCTGAGTCCCAGTCCATCACGAGCAGCTGGTTTCTAAGA
	TGCTATTTCCCGTATAAAGCATGAGACCGTGACTTGCCAGCCCCACAGAG
	CCCCGCCCTTGTCCATCACTGGCATCTGGACTCCAGCCTGGGTTGGGGCA
	AAGAGGGAAATGAGATCATGTCCTAACCCTGATCCTCTTGTCCCACAGAT
	ATCCAGAACCCTGACCCTGCCGTGTACCAGCTGAGAGACTCTAAATCCAG
	TGACAAGTCTGTCTGCCTATTCACCGATTTTGATTCTCAAACAAATGTGT
	CACAAAGTAAGGATTCTGATGTGTATATCACAGACAAAACTGTGCTAGAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatATGAGGTCT
	ATGGACTTCAAGAGCAACAGTGCTGTGGCCTGGAGCAACAAATCTGACTT
	TGCATGTGCAAACGCCTTCAACAACAGCATTATTCCAGAAGACACCTTCT
	TCCCCAGCCCAGGTAAGGGCAGCTTTGGTGCCTTCGCAGGCTGTTTCCTT
	GCTTCAGGAATGGCCAGGTTCTGCCCAGAGCTCTGGTCAATGATGTCTAA
	AACTCCTCTGATTGGTGGTCTCGGCCTTATCCATTGCCACCAAAACCCTC
	TTTTTACTAAGAAACAGTGAGCCTTGTTCTGGCAGTCCAGAGAATGACAC
	GGGAAAAAAGCAGATGAAGAGAAGGTGGCAGGAGAGGGCACGTGGCCCAG
	CCTCAGTCTCTCCAACTGAGTTCCTGCCTGCCTGCCTTTGCTCAGACTGT
	TTGCCCCTTACTGCTCTTCTAGGCCTCATTCTAAGCCCCTT
	(SEQ ID NO: 306)

pARBI-702:	TTCATTTCCATTTGAGTTGTTCTTATTGAGTCATCCTTCCTGTGGTAGCG	2541
TRAC_6_	GAACTCACTAAGGGGCCCATCTGGACCCGAGGTATTGTGATGATAAATTC
Exogenous_84	TGAGCACCTACCCCATCCCCAGAAGGGCTCAGAAATAAAATAAGAGCCAA
	GTCTAGTCGGTGTTTCCTGTCTTGAAACACAATACTGTTGGCCCTGGAAG
	AATGCACAGAATCTGTTTGTAAGGGGATATGCACAGAAGCTGCAAGGGAC
	AGGAGGTGCAGGAGCTGCAGGCCTCCCCCACCCAGCCTGCTCTGCCTTGG
	GGAAAACCGTGGGTGTGTCCTGCAGGCCATGCAGGCCTGGGACATGCAAG
	CCCATAACCGCTGTGGCCTCTTGGTTTTACAGATACGAACCTAAACTTTC
	AAAACCTGTCAGTGATTGGGTTCCGAATCCTCCTCCTGAAAGTGGCCGGG
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatTTTAATCTG
	CTCATGACGCTGCGGCTGTGGTCCAGCTGAGGTGAGGGGCCTTGAAGCTG
	GGAGTGGGGTTTAGGGACGCGGGTCTCTGGGTGCATCCTAAGCTCTGAGA
	GCAAACCTCCCTGCAGGGTCTTGCTTTTAAGTCCAAAGCCTGAGCCCACC
	AAACTCTCCTACTTCTTCCTGTTACAAATTCCTCTTGTGCAATAATAATG
	GCCTGAAACGCTGTAAAATATCCTCATTTCAGCCGCCTCAGTTGCACTTC
	TCCCCTATGAGGTAGGAAGAACAGTTGTTTAGAAACGAAGAAACTGAGGC
	CCCACAGCTAATGAGTGGAGGAAGAGAGACACTTGTGTACACCACATGCC
	TTGTGTTGTACTTCTCTCACCGTGTAACCTCCTCATGTCCTCTCTCCCCA
	GTACGGCTCTCTTAGCTCAGTAGAAAGAAGACATTACACTC
	(SEQ ID NO: 307)

pARBI-703:	CAGTCCATCACGAGCAGCTGGTTTCTAAGATGCTATTTCCCGTATAAAGC	2541
TRAC_	ATGAGACCGTGACTTGCCAGCCCCACAGAGCCCCGCCCTTGTCCATCACT
Exogenous_83	GGCATCTGGACTCCAGCCTGGGTTGGGGCAAAGAGGGAAATGAGATCATG
	TCCTAACCCTGATCCTCTTGTCCCACAGATATCCAGAACCCTGACCCTGC
	CGTGTACCAGCTGAGAGACTCTAAATCCAGTGACAAGTCTGTCTGCCTAT
	TCACCGATTTTGATTCTCAAACAAATGTGTCACAAAGTAAGGATTCTGAT
	GTGTATATCACAGACAAAACTGTGCTAGACATGAGGTCTATGGACTTCAA
	GAGCAACAGTGCTGTGGCCTGGAGCAACAAATCTGACTTTGCATGTGCAA
	ACGCCTTCAACAACAGCATTATTCCAGAAGACACCTTCTTCCCCAGCCCA
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGGTAAGGGC
	AGCTTTGGTGCCTTCGCAGGCTGTTTCCTTGCTTCAGGAATGGCCAGGTT
	CTGCCCAGAGCTCTGGTCAATGATGTCTAAAACTCCTCTGATTGGTGGTC
	TCGGCCTTATCCATTGCCACCAAAACCCTCTTTTTACTAAGAAACAGTGA
	GCCTTGTTCTGGCAGTCCAGAGAATGACACGGGAAAAAAGCAGATGAAGA
	GAAGGTGGCAGGAGAGGGCACGTGGCCCAGCCTCAGTCTCTCCAACTGAG
	TTCCTGCCTGCCTGCCTTTGCTCAGACTGTTTGCCCCTTACTGCTCTTCT
	AGGCCTCATTCTAAGCCCCTTCTCCAAGTTGCCTCTCCTTATTTCTCCCT
	GTCTGCCAAAAAATCTTTCCCAGCTCACTAAGTCAGTCTCACGCAGTCAC
	TCATTAACCCACCAATCACTGATTGTGCCGGCACATGAATG
	(SEQ ID NO: 308)

pARBI-704:	TGAGGAAGAAGCGCGGGCGGCGCCTTCGGGAGGCGAGCAGGCAGCAGTTG	2541
TRIM28_1_	GCCGTGCCGTAGCAGCGTCCCGCGCGCGGCGGGCAGCGGCCCAGGAGGCG
Exogenous_85	CGTGGCGGCGCTCGGCCTCGCGGCGGCGGCGGCGGCAGCGGCCCAGCAGT
	TGGCGGCGAGCGCGTCTGCGCCTGCGCGGCGGGCCCCGCGCCCCTCCTCC
	CCCCCTGGGCGCCCCCGGCGGCGTGTGAATGGCGGCCTCCGCGGCGGCAG
	CCTCGGCAGCAGCGGCCTCGGCCGCCTCTGGCAGCCCGGGCCCGGGCGAG
	GGCTCCGCTGGCGGCGAAAAGCGCTCCACCGCCCCTTCGGCCGCAGCCTC
	GGCCTCTGCCTCAGCCGCGGCGTCGTCGCCCGCGGGGGGCGGCGCCGAGG
	CGCTGGAGCTGCTGGAGCACTGCGGCGTGTGCAGAGAGCGCCTGCGACCC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGAGAGGGAG
	CCCCGCCTGCTGCCCTGTTTGCACTCGGCCTGTAGTGCCTGCTTAGGGCC
	CGCGGCCCCCGCCGCCGCCAACAGCTCGGGGGACGGCGGGGCGGCGGGCG
	ACGGCACCGGTAAGTACGAAGTGATCGGTGCCACCCCTCCCCCTACTCTC
	TGCCTTTGATTCCGACTGGGTGCAGAGATGAGGATGCCACCTGGGCGAGA
	GGATGGGGGCCCGGACAGGGCACGGGAAATACTTTCTGGGTCCTGCATAC
	GAACGTGGGTTTGTGCTGGCCGCTGAGATGGGACATCTGACTAAAGTTGG
	AGAAAAGAAGGCTCGGGGAGGGGAGGGGCTGGTTCGCTGCGGGATAATGG
	TCGGGGGCCCACCCAGCAGGGGAATGGTGGGGGCCATAACCTGGGTGGGA
	ACTTGTAACAGTCTCCCACATCCCTGCTTCTCGAAGTGGTG
	(SEQ ID NO: 309)

pARBI-705:	TCGAAGTGGTGGACTGTCCCGTGTGCAAGCAACAGTGCTTCTCCAAAGAC	2541
TRIM28_2_	ATCGTGGAGAATTATTTCATGCGTGATAGTGGCAGCAAGGCTGCCACCGA
Exogenous_86	CGCCCAGGATGCGAACCAGGTGCGTCCTATCTCAGCAACCACAAGGAGGT
	TTCTGGGGAGGGGGCATCTGCGCAGGAGGAGCTTGGCACCAGCTCCAGGC
	TGTTACTCCACTTTCCCAAGGCTCTGGGTGGGCTGCCTAGGTTGGGTCAA
	GGGACCAATCTTAAATCTCCGGTTGTATTTTCTGGGATGTAAACGTGGAT
	CTATCAAGTIGTCTTGCCTTCTCTGACCCTGCCTTTGTCTGGCAGTGCTG
	CACTAGCTGTGAGGATAATGCCCCAGCCACCAGCTACTGTGTGGAGTGCT
	CGGAGCCTCTGTGTGAGACCTGTGTAGAGGCGCACCAGCGGGTGAAGTAC
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatACCAAGGAC
	CATACTGTGCGCTCTACTGGTACATGAGGCTGAGGGGGGCTGTTGGAGTT
	GTTCTCCCATGTGTGCCCTCAGTTGCTTTTATGATGTTGGTTGCATCTGG
	TGGATGGGTCCTAGAGTTCTCTAGGGGGTGCCGCCCGAAGGGCCCGAGGG
	CAGAACTCCAGAAGCAGAAAAACTGGGGTTGTGGTGTGTAGTCTCTAGGG
	CCTAGGTGGGAGAGGGTGGGAAGGGGAAATAAGGGAGACCTTAATGTGCT
	GCAGGGAGGTACAAAGGGTTTGAGAAGGCTTATCAGGGAGTTGTCAGACC
	TGGTGGTGAAGGGCTCAGCATATGCAAACAGGGAAAGGCATGGTGTGAAG
	GGCTTTCTGGGTTTGTGGTTCCCTGGCACACATCTGGTATAAGATGCTGC
	TAGGGAAAGTAGACTGTGGGTCCATGGATTATAAGTGATGA
	(SEQ ID NO: 310)

pARBI-706:	GGCGCCCAATGCGCGTGCGCGGCGGCGTCGGCGCCAGTTATTTCTGTCCC	2541
TRIM28_3_	GCCCCCCGGCCTCGGCTCTTTCTGCGAGCGGGCGCGCGGGCGAGCGGTTG
Exogenous_87	TGCTTGTGCTTGTGGCGCGTGGTGCGGGTTTCGGCGGCGGCTGAGGAAGA
	AGCGCGGGCGGCGCCTTCGGGAGGCGAGCAGGCAGCAGTTGGCCGTGCCG
	TAGCAGCGTCCCGCGCGCGGCGGGCAGCGGCCCAGGAGGCGCGTGGCGGC
	GCTCGGCCTCGCGGCGGCGGCGGCGGCAGCGGCCCAGCAGTTGGCGGCGA
	GCGCGTCTGCGCCTGCGCGGCGGGCCCCGCGCCCCTCCTCCCCCCCTGGG
	CGCCCCCGGCGGCGTGTGAATGGCGGCCTCCGCGGCGGCAGCCTCGGCAG
	CAGCGGCCTCGGCCGCCTCTGGCAGCCCGGGCCCGGGCGAGGGCTCCGCT
	tgacgactgtgccttctagttgccagccatctgttgtttgcccctccccc
	gtgccttccttgaccctggaaggtgccactcccactgtcctttcctaata
	aaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctgg
	ggggtggggtggggcaggacagcaagggggaggattgggaagacaatagc
	aggcatgctggggatgcggtgggctctatggGGATCTGCGATCGCTCCGG
	TGCCCGTCAGTGGGCAGAGCGCACATCGCCCACAGTCCCCGAGAAGTTGG
	GGGGAGGGGTCGGCAATTGAACGGGTGCCTAGAGAAGGTGGCGCGGGGTA
	AACTGGGAAAGTGATGTCGTGTACTGGCTCCGCCTTTTTCCCGAGGGTGG
	GGGAGAACCGTATATAAGTGCAGTAGTCGCCGTGAACGTTCTTTTTCGCA
	ACGGGTTTGCCGCCAGAACACAGCTGAAGCTTCGAGGGGCTCGCATCTCT
	CCTTCACGCGCCCGCCGCCCTACCTGAGGCCGCCATCCACGCCGGTTGAG
	TCGCGTTCTGCCGCCTCCCGCCTGTGGTGCCTCCTGAACTGCGTCCGCCG
	TCTAGGTAAGTTTAAAGCTCAGGTCGAGACCGGGCCTTTGTCCGGCGCTC
	CCTTGGAGCCTACCTAGACTCAGCCGGCTCTCCACGCTTTGCCTGACCCT
	GCTTGCTCAACTCTACGTCTTTGTTTCGTTTTCTGTTCTGCGCCGTTACA
	GATCCAAGCTGTGACCGGCGCCTACTCTAGAGCTAGCGAATTgccgccac
	cATGGTGAGCAAGGGCGAGGAGCTGTTCACCGGGGTGGTGCCCATCCTGG
	TCGAGCTGGACGGCGACGTAAACGGCCACAAGTTCAGCGTGTCCGGCGAG
	GGCGAGGGCGATGCCACCTACGGCAAGCTGACCCTGAAGTTCATCTGCAC
	CACCGGCAAGCTGCCCGTGCCCTGGCCCACCCTCGTGACCACCCTGACCT
	ACGGCGTGCAGTGCTTCAGCCGCTACCCCGACCACATGAAGCAGCACGAC
	TTCTTCAAGTCCGCCATGCCCGAAGGCTACGTCCAGGAGCGCACCATCTT
	CTTCAAGGACGACGGCAACTACAAGACCCGCGCCGAGGTGAAGTTCGAGG
	GCGACACCCTGGTGAACCGCATCGAGCTGAAGGGCATCGACTTCAAGGAG
	GACGGCAACATCCTGGGGCACAAGCTGGAGTACAACTACAACAGCCACAA
	CGTCTATATCATGGCCGACAAGCAGAAGAACGGCATCAAGGTGAACTTCA
	AGATCCGCCACAACATCGAGGACGGCAGCGTGCAGCTCGCCGACCACTAC
	CAGCAGAACACCCCCATCGGCGACGGCCCCGTGCTGCTGCCCGACAACCA
	CTACCTGAGCACCCAGTCCAAGCTGAGCAAAGACCCCAACGAGAAGCGCG
	ATCACATGGTCCTGCTGGAGTTCGTGACCGCCGCCGGGATCACTCTCGGC
	ATGGACGAGCTGTACAAatgattgtttattgcagcttataatggttacaa
	ataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgc
	attctagttgtggtttgtccaaactcatcaatgtatcttatGGCGGCGAA
	AAGCGCTCCACCGCCCCTTCGGCCGCAGCCTCGGCCTCTGCCTCAGCCGC
	GGCGTCGTCGCCCGCGGGGGGCGGCGCCGAGGCGCTGGAGCTGCTGGAGC
	ACTGCGGCGTGTGCAGAGAGCGCCTGCGACCCGAGAGGGAGCCCCGCCTG
	CTGCCCTGTTTGCACTCGGCCTGTAGTGCCTGCTTAGGGCCCGCGGCCCC
	CGCCGCCGCCAACAGCTCGGGGGACGGCGGGGCGGCGGGCGACGGCACCG
	GTAAGTACGAAGTGATCGGTGCCACCCCTCCCCCTACTCTCTGCCTTTGA
	TTCCGACTGGGTGCAGAGATGAGGATGCCACCTGGGCGAGAGGATGGGGG
	CCCGGACAGGGCACGGGAAATACTTTCTGGGTCCTGCATACGAACGTGGG
	TTTGTGCTGGCCGCTGAGATGGGACATCTGACTAAAGTTGG
	(SEQ ID NO: 311)

Claims

1. A method of editing a cell having chromosomal DNA, comprising inserting at least one sequence comprising a transgene within a safe harbor locus in the chromosomal DNA of the cell, wherein the safe harbor locus is at any one or more of an sgRNA target loci selected from: chr11:128340000-128350000, chr15:92830000-92840000, chr10:33130000-33140000, chr10:72290000-72300000, chr11:65425000-65427000 (NEAT1), chr16: 11220000-11230000, chr2:87460000-87470000, chr3:186510000-186520000, chr3:59450000-59460000, chr8:127980000-128000000, chr9:7970000-7980000, APRT, B2M, CAPNS1, CBLB, CD2, CD3E, CD3G, CD5, EDF1, FTL, PTEN, PTPN2, PTPN6, PTPRC, PTPRCAP, RPS23, RTRAF, SERF2, SLC38A1, SMAD2, SOCS1, SRP14, SRSF9, SUB1, TET2, TIGIT, TRAC, or TRIM28.

2. The method of claim 1, wherein the sgRNA target locus is chr11:128340000-128350000 or chr15:92830000-92840000.

3. The method of claim 1, wherein the sgRNA target locus comprises an integration site comprising a start coordinate of chr11:128342576.

4. The method of claim 1, wherein the sgRNA target locus comprises an integration site comprising a start coordinate of chr15:92831131.

5. The method of claim 1, wherein the at least one sequence is operatively linked to an endogenous promoter.

6. The method of claim 1, wherein the at least one sequence is operatively linked to an exogenous promoter.

7. The method of claim 6, wherein the exogenous promoter is an EF1α promoter.

8. The method of claim 1, wherein the cell is a natural killer (NK) cell, an induced pluripotent stem cell (iPSC), a human pluripotent stem cell (HSPC), a T cell, a CD8+ T cell, or a T cell progenitor cell.

9. The method of claim 8, wherein the cell is a T cell, a CD8+ T cell, or a T cell progenitor cell.

10. The method of claim 8, wherein the cell is a CD8+ T cell.

11. The method of claim 13, wherein the transgene encodes a protein, a therapeutic agent, a cancer-specific therapeutic agent, a T-cell receptor (TCR), a Prime Receptor (primeR), or a chimeric antigen receptor (CAR).

12. The method of claim 1, wherein the transgene encodes a chimeric antigen receptor (CAR).

13. The method of claim 1, wherein the transgene encodes a T-cell receptor (TCR).

14. The method of claim 1, wherein the transgene encodes a Prime Receptor (primeR).

15. The method of claim 1, wherein the transgene encodes an shRNA, an miRNA, or an siRNA.

16. The method of claim 1, wherein the at least one sequence is inserted using a homology-directed repair or a homology independent targeted insertion.

17. The method of claim 1, wherein the at least one sequence is inserted using one or more guide ribonucleic acids (gRNAs) and one or more Cas9 endonucleases, optionally wherein the one or more gRNAs comprises any one of SEQ ID NOS: 1-120.

18. The method of claim 17, wherein the one or more gRNAs comprises SEQ ID NO: 94.

19. The method of claim 17, wherein the one or more gRNAs comprises SEQ ID NO: 102.

20. A guide ribonucleic acid (gRNA) for editing a cell at a safe harbor locus, wherein the gRNA comprises any one of SEQ ID NOS:1-120.

21. An ex vivo method of obtaining an engineered cell or population thereof, comprising:

a. obtaining a cell; and

b. genetically modifying the cell by inserting at least one sequence encoding a transgene within a safe harbor locus, wherein the safe harbor locus is at any one or more of an sgRNA target loci selected from: chr10:33130000-33140000, chr10:72290000-72300000, chr11:128340000-128350000, chr11:65425000-65427000 (NEAT1), chr15:92830000-92840000, chr16:11220000-11230000, chr2:87460000-87470000, chr3:186510000-186520000, chr3:59450000-59460000, chr8:127980000-128000000, chr9:7970000-7980000, APRT, B2M, CAPNS1, CBLB, CD2, CD3E, CD3G, CD5, EDF1, FTL, PTEN, PTPN2, PTPN6, PTPRC, PTPRCAP, RPS23, RTRAF, SERF2, SLC38A1, SMAD2, SOCS1, SRP14, SRSF9, SUB1, TET2, TIGIT, TRAC, or TRIM28.