US20220016002A1 - Non-aluminium antiperspirant compositions - Google Patents
Non-aluminium antiperspirant compositions Download PDFInfo
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- US20220016002A1 US20220016002A1 US17/297,836 US201917297836A US2022016002A1 US 20220016002 A1 US20220016002 A1 US 20220016002A1 US 201917297836 A US201917297836 A US 201917297836A US 2022016002 A1 US2022016002 A1 US 2022016002A1
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- United States
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- composition
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- amphiphilic material
- volatile silicone
- ethanol
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- 239000000203 mixture Substances 0.000 title claims abstract description 86
- 230000001166 anti-perspirative effect Effects 0.000 title claims abstract description 25
- 239000003213 antiperspirant Substances 0.000 title claims abstract description 25
- 239000004411 aluminium Substances 0.000 title claims description 7
- 229910052782 aluminium Inorganic materials 0.000 title claims description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 79
- 239000000463 material Substances 0.000 claims abstract description 45
- 229920001296 polysiloxane Polymers 0.000 claims abstract description 30
- 239000003906 humectant Substances 0.000 claims abstract description 20
- WNWHHMBRJJOGFJ-UHFFFAOYSA-N 16-methylheptadecan-1-ol Chemical compound CC(C)CCCCCCCCCCCCCCCO WNWHHMBRJJOGFJ-UHFFFAOYSA-N 0.000 claims abstract description 10
- ARIWANIATODDMH-AWEZNQCLSA-N 1-lauroyl-sn-glycerol Chemical compound CCCCCCCCCCCC(=O)OC[C@@H](O)CO ARIWANIATODDMH-AWEZNQCLSA-N 0.000 claims abstract description 6
- ARIWANIATODDMH-UHFFFAOYSA-N Lauric acid monoglyceride Natural products CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 claims abstract description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 48
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 42
- 239000003380 propellant Substances 0.000 claims description 21
- CLAHOZSYMRNIPY-UHFFFAOYSA-N 2-hydroxyethylurea Chemical compound NC(=O)NCCO CLAHOZSYMRNIPY-UHFFFAOYSA-N 0.000 claims description 10
- 239000000443 aerosol Substances 0.000 claims description 9
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical group COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 claims description 8
- -1 siloxanes Chemical class 0.000 claims description 7
- YFCGDEUVHLPRCZ-UHFFFAOYSA-N [dimethyl(trimethylsilyloxy)silyl]oxy-dimethyl-trimethylsilyloxysilane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C YFCGDEUVHLPRCZ-UHFFFAOYSA-N 0.000 claims description 6
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 6
- UQEAIHBTYFGYIE-UHFFFAOYSA-N hexamethyldisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)C UQEAIHBTYFGYIE-UHFFFAOYSA-N 0.000 claims description 5
- 150000003839 salts Chemical class 0.000 claims description 5
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 claims description 4
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 claims description 3
- 125000003277 amino group Chemical group 0.000 claims description 3
- FBZANXDWQAVSTQ-UHFFFAOYSA-N dodecamethylpentasiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C FBZANXDWQAVSTQ-UHFFFAOYSA-N 0.000 claims description 3
- 229940087203 dodecamethylpentasiloxane Drugs 0.000 claims description 3
- 229910052726 zirconium Inorganic materials 0.000 claims description 3
- 239000004215 Carbon black (E152) Substances 0.000 claims description 2
- 229930195733 hydrocarbon Natural products 0.000 claims description 2
- 150000002430 hydrocarbons Chemical class 0.000 claims description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- DHXVGJBLRPWPCS-UHFFFAOYSA-N Tetrahydropyran Chemical compound C1CCOCC1 DHXVGJBLRPWPCS-UHFFFAOYSA-N 0.000 claims 1
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 8
- 239000002781 deodorant agent Substances 0.000 description 6
- 239000004599 antimicrobial Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000002537 cosmetic Substances 0.000 description 4
- 230000000845 anti-microbial effect Effects 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 150000002632 lipids Chemical class 0.000 description 3
- 239000004973 liquid crystal related substance Substances 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 2
- CRDAMVZIKSXKFV-UHFFFAOYSA-N farnesol Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCO CRDAMVZIKSXKFV-UHFFFAOYSA-N 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 150000003754 zirconium Chemical class 0.000 description 2
- CRDAMVZIKSXKFV-FBXUGWQNSA-N (2-cis,6-cis)-farnesol Chemical compound CC(C)=CCC\C(C)=C/CC\C(C)=C/CO CRDAMVZIKSXKFV-FBXUGWQNSA-N 0.000 description 1
- 239000000260 (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol Substances 0.000 description 1
- XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 description 1
- OWEGWHBOCFMBLP-UHFFFAOYSA-N 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one Chemical compound C1=CN=CN1C(C(=O)C(C)(C)C)OC1=CC=C(Cl)C=C1 OWEGWHBOCFMBLP-UHFFFAOYSA-N 0.000 description 1
- KDTZBYPBMTXCSO-UHFFFAOYSA-N 2-phenoxyphenol Chemical compound OC1=CC=CC=C1OC1=CC=CC=C1 KDTZBYPBMTXCSO-UHFFFAOYSA-N 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 1
- 229920001090 Polyaminopropyl biguanide Polymers 0.000 description 1
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 1
- OGELJRHPEZALCC-UHFFFAOYSA-N [3-(2,3-dihydroxypropoxy)-2-hydroxypropyl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCC(O)COCC(O)CO OGELJRHPEZALCC-UHFFFAOYSA-N 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 159000000013 aluminium salts Chemical class 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
- RLGQACBPNDBWTB-UHFFFAOYSA-N cetyltrimethylammonium ion Chemical class CCCCCCCCCCCCCCCC[N+](C)(C)C RLGQACBPNDBWTB-UHFFFAOYSA-N 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- 229960003344 climbazole Drugs 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- GPLRAVKSCUXZTP-UHFFFAOYSA-N diglycerol Chemical compound OCC(O)COCC(O)CO GPLRAVKSCUXZTP-UHFFFAOYSA-N 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 description 1
- 229940043259 farnesol Drugs 0.000 description 1
- 229930002886 farnesol Natural products 0.000 description 1
- 125000001153 fluoro group Chemical group F* 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 229940031575 hydroxyethyl urea Drugs 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 229960004125 ketoconazole Drugs 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 229960003966 nicotinamide Drugs 0.000 description 1
- 235000005152 nicotinamide Nutrition 0.000 description 1
- 239000011570 nicotinamide Substances 0.000 description 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- 229940093424 polyaminopropyl biguanide Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000010677 tea tree oil Substances 0.000 description 1
- 229940111630 tea tree oil Drugs 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000010678 thyme oil Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 229960003500 triclosan Drugs 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 229940043810 zinc pyrithione Drugs 0.000 description 1
- PICXIOQBANWBIZ-UHFFFAOYSA-N zinc;1-oxidopyridine-2-thione Chemical compound [Zn+2].[O-]N1C=CC=CC1=S.[O-]N1C=CC=CC1=S PICXIOQBANWBIZ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/591—Mixtures of compounds not provided for by any of the codes A61K2800/592 - A61K2800/596
Definitions
- the present invention is in the field of cosmetic compositions and their use as antiperspirants, in particular, non-aluminium antiperspirant compositions.
- EP 550,960 A1 (Unilever, 1992) discloses the use as an antiperspirant active of an amphiphilic material which forms, upon contact with perspiration, a water-insoluble liquid crystal phase of greater than one dimensional periodicity. This publication does not disclose ethanolic compositions, nor their stability issues.
- WO 94/024993 discloses an antiperspirant composition
- an amphiphilic material which forms, upon contact with perspiration, a water-insoluble liquid crystal phase of greater than one dimensional periodicity, in a cosmetic vehicle comprising a volatile silicone and containing less than 10% by weight of the total composition of a short chain monohydric alcohol.
- composition that has a high degree of storage stability and that delivers skin care benefits.
- an antiperspirant composition comprising ethanol, amphiphilic material, volatile silicone and a humectant, the amphiphilic material being a mixture consisting of glycerol monolaurate and isostearyl alcohol at a ratio of from 25:75 to 45:, wherein:
- an antiperspirant aerosol composition comprising the addition of propellant to a composition according to the first aspect of the invention.
- a cosmetic method of attaining an antiperspirant benefit comprising the topical application of a composition according to the first aspect of the invention.
- ambient conditions refers to 20° C. and 1 atmosphere pressure, unless otherwise indicated.
- cosmetic methods and compositions should be understood to mean non-therapeutic methods and compositions, respectively.
- an “amphiphilic material” is a material defined by having both hydrophilic and hydrophobic portions in its structure.
- water-insoluble means having a solubility in water of less than 0.1% by weight (at 37° C.).
- Antiperspirant compositions according to the present invention are preferably free of aluminium or zirconium antiperspirant salts. Indeed, they are more preferably free of any aluminium or zirconium salts.
- free of means having less 0.1% and preferably less than 0.01% of the specified component or components.
- a “volatile silicone” is a silicone having a vapour pressure of greater than 1 Pa at 25° C.
- compositions of the invention are particularly effectively when applied to the underarm regions of the human body and/or the feet.
- the compositions are especially effectively when applied to the underarm regions of the human body.
- Antiperspirant aerosol compositions consist of a propellant and a base.
- the components of the base are typically mixed together first and the propellant is added last in a process sometimes called “gassing”. It is important that the base has good storage stability because there can be a significant period between the preparation of the base and the addition of the propellant.
- the “base” of an antiperspirant aerosol composition is all the components of the total composition other than the propellant.
- the fully formulated antiperspirant composition has good storage stability, so that it can survive prolonged transit to stores and extended periods on shelf prior to purchase and use.
- the amphiphilic material is a mixture consisting of glycerol monolaurate and isostearyl alcohol at a ratio of from 25 75 to 45:55
- amphiphilic material is at least 10% of the tri-component mixture consisting of ethanol, amphiphilic material and volatile siloxane.
- the ratio of amphiphilic material to (ethanol+volatile silicone) is from 1:9 to 2:3, this ratio being alternatively stated as being from 10:90 to 40:60.
- the amount of amphiphilic material in the tri-component mixture consisting of ethanol, amphiphilic material and volatile siloxane is from 10% to 40%.
- amphiphilic material serves as the antiperspirant active for the composition, just as in the prior publications EP 550,960 A1 and WO 94/024993 by Unilever.
- the amphiphilic material physically swells and forms a liquid crystal structure on contact with perspiration, hence enhancing the pore-blocking effect.
- the content of the amphiphilic material in the total composition, ignoring any propellant therein, is preferably at least 10%, more preferably at least 12% and most preferably at least 15%.
- the volatile silicone and its level of incorporation serves to reduce potential irritation and/or promote the good sensory properties of the composition.
- the ratio of volatile silicone to (ethanol+amphiphilic material) in compositions of the invention is from 1:9 to 11:9, alternatively expressed as from 10:90 to 55:45. This equates to the volatile silicone being present at from 10% to 55% of the tri-component mixture consisting of ethanol, amphiphilic material and volatile siloxane. Preferably, the volatile silicone is present at from 10% to 50% and more preferably at from 15 to 40% of the tri-component mixture consisting of ethanol, amphiphilic material and volatile siloxane.
- the content of volatile silicone in the total composition is preferably from 10% to 67%, more preferably from 10% to 50% most preferably from 15% to 40%.
- the volatile silicone comprises greater than 90% by weight of, or consists of siloxanes having from 2 to 6 silicone atoms, arranged in either a cyclic or linear fashion.
- the volatile silicone comprises greater than 90% by weight of, or consists of, siloxanes selected from the group consisting of hexamethyldisiloxane, octamethyltrisiiloxane, decamethyltetrasiloxane, dodecamethylpentasiloxane and decamethylcyclopentasiloxane.
- the volatile silicone comprises greater than 90% by weight of, or consists of, siloxanes selected from the group consisting of hexamethyldisiloxane, octamethyltrisiiloxane, decamethyltetrasiloxane and decamethylcyclopentasiloxane.
- Ethanol is an essential component of compositions of the invention, serving to aid the solubilisation of the amphiphilic material.
- the ratio of ethanol to (amphiphilic material+volatile silicone) is from 3:7 to 3:2, alternative expressed as from 30:70 to 60:40. This equates to ethanol being present at from 30 to 60% of the tri-component mixture consisting of ethanol, amphiphilic material and volatile silicone.
- the ratio of ethanol to amphiphilic material is at least 10:7. More preferably this ratio is at least 2:1 or 67:33.
- the content of ethanol in the total composition, ignoring any propellant therein, is preferably at least 30%, more preferably at least 33% and most preferably at least 35%.
- a humectant is an essential component of compositions od the invention.
- Humectants used in the present invention are hygroscopic materials having the ability to form hydrogen-bonds.
- the purpose of the humectant is to aid skin care by retaining moisture in the skin. This can improve the barrier properties of the skin.
- Preferred humectants for use in the present invention have multiple hydrophilic groups, in particular hydroxyl groups and/or amine groups. Such materials can be particularly effective hydrogen-bond donors making them particular good humectants.
- amine groups include such groups linked to a carbonyl group to form an amide, whether part of larger functional group or not.
- humectants are selected from glycerol, 2-hydroxyethyl urea (HEU) and propylene glycol (PG).
- humectants are polyhydroxylated materials like PG, dipropylene glycol (DPG) and glycerol.
- An especially preferred humectant is glycerol.
- the total amount of humectant used is from 0.1 to 10%, excluding any propellant that may be present. This level is preferably from 0.5 to 6% and more preferably from 1 to 5% of the composition excluding any propellant that may be present.
- Humectants have been difficult to incorporate into conventional antiperspirant compositions comprising aluminium and zirconium antiperspirant salts. We have found that they can be incorporated into the alternative antiperspirant compositions of the present invention by careful selection of the amounts and ratios of components. Without such selection, multiphasic or unstable compositions result.
- the composition is an antiperspirant aerosol composition comprising a propellant.
- the propellant preferably comprises from 35 to 95% of the total composition, more preferably from 40 to 90% and most preferably from 50 to 85% of the total composition.
- the propellant is commonly either a compressed gas or a material that boils at below ambient temperature, preferably at below 0° C., and especially at below ⁇ 10° C.
- compressed gasses include nitrogen and carbon dioxide.
- low boiling point materials include dimethyl ether.
- Other possible low boiling point materials that may be used as propellants are hydrofluorocarbons containing from 2 to 4 carbons, at least one hydrogen and 3 to 7 fluorine atoms.
- the propellant used comprises dimethyl ether or hydrocarbon.
- compositions according to the invention are aerosol compositions, they can be made in a conventional manner by first preparing a base composition, charging the base composition into the aerosol can, fitting a valve assembly into the mouth of the can, thereby sealing the can, and thereafter charging propellant into the can to a desired pressure, and finally fitting an actuator on or over the valve assembly.
- compositions of the invention is a deodorant active.
- deodorant active typically antimicrobial agents active against bacterial on the skin of the human body. These serve to reduce malodour and especially useful in compositions in which the amphiphilic material is not itself an antimicrobial agent.
- the level of incorporation is preferably 0.01%-5%, more preferably from 0.01-2% and most preferably from 0.03%-0.5% by weight of the total composition.
- Preferred anti-microbial deodorant agents are those that are more efficacious than simple alcohols such as ethanol.
- Particularly preferred anti-microbial deodorant agents are soluble in ethanol, meaning that they a solubility in ethanol of at least 10 g/L at 20° C.
- Suitable anti-microbial deodorant agents include niacinamide; quaternary ammonium compounds, like cetyltrimethylammonium salts; chlorhexidine and salts thereof; and diglycerol monocaprate, diglycerol monolaurate, glycerol monolaurate, and similar materials, as described in “Deodorant Ingredients”, S. A. Makin and M. R. Lowry, in “Antiperspirants and Deodorants”, Ed. K. Laden (1999, Marcel Dekker, New York).
- polyhexamethylene biguanide salts also known as polyaminopropyl biguanide salts
- an example being Cosmocil CQ available from Arch Chemicals, 2′,4,4′-trichloro,2-hydroxy-diphenyl ether (triclosan), 3,7,11-trimethyldodeca-2,6,10-trienol (farnesol), essential oils such as Tea Tree Oil and Thyme Oil, climbazole, octapyrox, ketoconazole, zinc pyrithione and mixtures thereof.
- a preferred optional component is a preservative, such as ethyl or methyl parabens or BHT (butyl hydroxy toluene), typically in an amount of from 0.01 to 0.1% by weight of the total composition.
- a preservative such as ethyl or methyl parabens or BHT (butyl hydroxy toluene)
- amphiphilic material used in these examples is designated as “lipid” and was a 60:40 blend of glycerol monolaurate and isostearyl alcohol.
- the ethanol used in these examples was absolute alcohol.
- the volatile silicone used in these examples was either DC200 or a 15:85 mix of DC245 and DC200, referred to in Table 1 as “Mix”.
- humectants used in these examples were hydroxyethyl urea (HEU), propylene glycol (PG) and glycerol.
- compositions indicated in Table 1 were prepared by methods known in the art.
- the stability of the examples 5 to 8 and 12 to 15 was monitored for 8 weeks at 20° C.
- the stability of all of the other examples and comparative examples was monitored for 4 weeks at ambient temperature.
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EP18209520 | 2018-11-30 | ||
PCT/EP2019/078941 WO2020108885A1 (en) | 2018-11-30 | 2019-10-23 | Non-aluminium antiperspirant compositions |
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US (1) | US20220016002A1 (es) |
EP (1) | EP3886796A1 (es) |
CN (1) | CN113164351A (es) |
AU (1) | AU2019389075B2 (es) |
BR (1) | BR112021008466A2 (es) |
EA (1) | EA202190945A1 (es) |
MX (1) | MX2021006190A (es) |
PH (1) | PH12021550980A1 (es) |
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AU2022420330A1 (en) | 2021-12-22 | 2024-06-13 | Unilever Global Ip Limited | Cosmetic sweat management compositions |
WO2023117481A1 (en) | 2021-12-22 | 2023-06-29 | Unilever Ip Holdings B.V. | Cosmetic sweat management compositions |
WO2023117480A1 (en) | 2021-12-22 | 2023-06-29 | Unilever Ip Holdings B.V. | Cosmetic sweat management compositions |
Citations (3)
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EP0251679A2 (en) * | 1986-06-30 | 1988-01-07 | Dow Corning Corporation | Stick vehicle for skin care substances |
US4822602A (en) * | 1987-04-29 | 1989-04-18 | The Procter & Gamble Company | Cosmetic sticks |
US20020146376A1 (en) * | 2001-02-01 | 2002-10-10 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Cosmetic products for the reduction of sweat acidity |
Family Cites Families (9)
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DE3068546D1 (en) * | 1979-11-07 | 1984-08-16 | Procter & Gamble | Antiperspirant compositions |
DE3740186A1 (de) * | 1987-06-24 | 1989-01-05 | Beiersdorf Ag | Desodorierende und antimikrobielle zusammensetzung zur verwendung in kosmetischen oder topischen zubereitungen |
CA2082561A1 (en) | 1991-11-12 | 1993-05-13 | Francis J. Leng | Antiperspirant materials and compositions |
GB2273872A (en) * | 1992-12-22 | 1994-07-06 | Unilever Plc | A method of treating skin |
AU6679894A (en) | 1993-04-30 | 1994-11-21 | Unilever Plc | Antiperspirant compositions |
GB9502495D0 (en) * | 1995-02-09 | 1995-03-29 | Unilever Plc | Antiperspirant compositions |
GB0516418D0 (en) * | 2005-08-10 | 2005-09-14 | Unilever Plc | Antiperspirant compositions |
US20090130042A1 (en) * | 2007-11-16 | 2009-05-21 | Conopco, Inc., D/B/A Unilever | Topical composition |
CA2738683C (en) * | 2008-10-23 | 2013-11-26 | The Procter & Gamble Company | Anhydrous antiperspirant compositions |
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2019
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- 2019-10-23 CN CN201980078918.9A patent/CN113164351A/zh active Pending
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- 2019-10-23 EP EP19789707.7A patent/EP3886796A1/en active Pending
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0251679A2 (en) * | 1986-06-30 | 1988-01-07 | Dow Corning Corporation | Stick vehicle for skin care substances |
US4822602A (en) * | 1987-04-29 | 1989-04-18 | The Procter & Gamble Company | Cosmetic sticks |
US20020146376A1 (en) * | 2001-02-01 | 2002-10-10 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Cosmetic products for the reduction of sweat acidity |
Non-Patent Citations (3)
Title |
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245 Fluid Material Safety Data Sheet (Year: 2006) * |
Octamethylcyclotetrasiloxane Material Safety Data Sheet (Year: 2014) * |
SF 1202 Material Safety Data Sheet (Year: 2003) * |
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PH12021550980A1 (en) | 2021-11-08 |
ZA202103148B (en) | 2022-10-26 |
CN113164351A (zh) | 2021-07-23 |
EP3886796A1 (en) | 2021-10-06 |
WO2020108886A1 (en) | 2020-06-04 |
BR112021008466A2 (pt) | 2021-08-03 |
MX2021006190A (es) | 2021-06-30 |
AU2019389075B2 (en) | 2023-05-11 |
EA202190945A1 (ru) | 2021-09-27 |
WO2020108885A1 (en) | 2020-06-04 |
AU2019389075A1 (en) | 2021-05-27 |
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