US20180221660A1 - Stimulator systems and methods for obstructive sleep apnea - Google Patents

Stimulator systems and methods for obstructive sleep apnea Download PDF

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Publication number
US20180221660A1
US20180221660A1 US15/885,618 US201815885618A US2018221660A1 US 20180221660 A1 US20180221660 A1 US 20180221660A1 US 201815885618 A US201815885618 A US 201815885618A US 2018221660 A1 US2018221660 A1 US 2018221660A1
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United States
Prior art keywords
electrode
nerve
electrode contacts
patient
cuff body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US15/885,618
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English (en)
Inventor
Harshit Suri
Joseph L. Calderon
Gregory Frederick Molnar
George S. Goding, Jr.
Alanie Atyabi
Siegmar Schmidt
William Dai
Brian Dearden
Desmond B. Keenan
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Alfred E Mann Foundation for Scientific Research
Original Assignee
Alfred E Mann Foundation for Scientific Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfred E Mann Foundation for Scientific Research filed Critical Alfred E Mann Foundation for Scientific Research
Priority to US15/885,618 priority Critical patent/US20180221660A1/en
Assigned to THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH reassignment THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KEENAN, DESMOND B., GODING, GEORGE S., Molnar, Gregory Frederick, DEARDEN, Brian, ATYABI, Alanie, CALDERON, JOSEPH L., DAI, WILLIAM, SCHMIDT, SIEGMAR, SURI, Harshit
Publication of US20180221660A1 publication Critical patent/US20180221660A1/en
Priority to US16/245,509 priority patent/US20190143110A1/en
Priority to US16/812,947 priority patent/US11638826B2/en
Priority to US16/992,439 priority patent/US20200368526A1/en
Priority to US17/083,532 priority patent/US11654284B2/en
Priority to US17/091,182 priority patent/US11642529B2/en
Priority to US18/296,805 priority patent/US20230241393A1/en
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/3611—Respiration control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/267—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the respiratory tract, e.g. laryngoscopes, bronchoscopes
    • A61B5/04886—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836—Measuring rate of CO2 production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/087—Measuring breath flow
    • A61B5/0878—Measuring breath flow using temperature sensing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/389—Electromyography [EMG]
    • A61B5/394—Electromyography [EMG] specially adapted for electroglottography or electropalatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4806—Sleep evaluation
    • A61B5/4818—Sleep apnoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3601—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of respiratory organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/378—Electrical supply
    • A61N1/3787—Electrical supply from an external energy source
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0219—Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Optics & Photonics (AREA)
  • Obesity (AREA)
  • Otolaryngology (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
US15/885,618 2017-02-01 2018-01-31 Stimulator systems and methods for obstructive sleep apnea Abandoned US20180221660A1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US15/885,618 US20180221660A1 (en) 2017-02-01 2018-01-31 Stimulator systems and methods for obstructive sleep apnea
US16/245,509 US20190143110A1 (en) 2017-02-01 2019-01-11 Stimulator systems and methods for obstructive sleep apnea
US16/812,947 US11638826B2 (en) 2017-02-01 2020-03-09 Stimulator systems and methods for obstructive sleep apnea
US16/992,439 US20200368526A1 (en) 2017-02-01 2020-08-13 Stimulator systems and methods for obstructive sleep apnea
US17/083,532 US11654284B2 (en) 2017-02-01 2020-10-29 Stimulator systems and methods for obstructive sleep apnea
US17/091,182 US11642529B2 (en) 2017-02-01 2020-11-06 Stimulator systems and methods for obstructive sleep apnea
US18/296,805 US20230241393A1 (en) 2017-02-01 2023-04-06 Stimulator systems and methods for obstructive sleep apnea

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762453311P 2017-02-01 2017-02-01
US15/885,618 US20180221660A1 (en) 2017-02-01 2018-01-31 Stimulator systems and methods for obstructive sleep apnea

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US16/245,509 Continuation US20190143110A1 (en) 2017-02-01 2019-01-11 Stimulator systems and methods for obstructive sleep apnea

Publications (1)

Publication Number Publication Date
US20180221660A1 true US20180221660A1 (en) 2018-08-09

Family

ID=61193177

Family Applications (7)

Application Number Title Priority Date Filing Date
US15/885,618 Abandoned US20180221660A1 (en) 2017-02-01 2018-01-31 Stimulator systems and methods for obstructive sleep apnea
US16/245,509 Abandoned US20190143110A1 (en) 2017-02-01 2019-01-11 Stimulator systems and methods for obstructive sleep apnea
US16/812,947 Active 2038-08-06 US11638826B2 (en) 2017-02-01 2020-03-09 Stimulator systems and methods for obstructive sleep apnea
US16/992,439 Abandoned US20200368526A1 (en) 2017-02-01 2020-08-13 Stimulator systems and methods for obstructive sleep apnea
US17/083,532 Active 2038-08-08 US11654284B2 (en) 2017-02-01 2020-10-29 Stimulator systems and methods for obstructive sleep apnea
US17/091,182 Active 2038-08-26 US11642529B2 (en) 2017-02-01 2020-11-06 Stimulator systems and methods for obstructive sleep apnea
US18/296,805 Pending US20230241393A1 (en) 2017-02-01 2023-04-06 Stimulator systems and methods for obstructive sleep apnea

Family Applications After (6)

Application Number Title Priority Date Filing Date
US16/245,509 Abandoned US20190143110A1 (en) 2017-02-01 2019-01-11 Stimulator systems and methods for obstructive sleep apnea
US16/812,947 Active 2038-08-06 US11638826B2 (en) 2017-02-01 2020-03-09 Stimulator systems and methods for obstructive sleep apnea
US16/992,439 Abandoned US20200368526A1 (en) 2017-02-01 2020-08-13 Stimulator systems and methods for obstructive sleep apnea
US17/083,532 Active 2038-08-08 US11654284B2 (en) 2017-02-01 2020-10-29 Stimulator systems and methods for obstructive sleep apnea
US17/091,182 Active 2038-08-26 US11642529B2 (en) 2017-02-01 2020-11-06 Stimulator systems and methods for obstructive sleep apnea
US18/296,805 Pending US20230241393A1 (en) 2017-02-01 2023-04-06 Stimulator systems and methods for obstructive sleep apnea

Country Status (5)

Country Link
US (7) US20180221660A1 (fr)
EP (1) EP3576838A1 (fr)
AU (1) AU2018215194B2 (fr)
CA (1) CA3071628A1 (fr)
WO (1) WO2018144631A1 (fr)

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WO2020181123A1 (fr) * 2019-03-06 2020-09-10 Medtronic Xomed, LLC Système de simulation de muscle lingual sensible à la position pour apnée obstructive du sommeil
US11167127B2 (en) * 2020-01-24 2021-11-09 Medtronic Xomed, Inc. System and method for therapy
US11167140B2 (en) * 2020-01-24 2021-11-09 Medtronic Xomed, Inc. System and method for therapy
US11298540B2 (en) 2017-08-11 2022-04-12 Inspire Medical Systems, Inc. Cuff electrode
US11324950B2 (en) 2016-04-19 2022-05-10 Inspire Medical Systems, Inc. Accelerometer-based sensing for sleep disordered breathing (SDB) care
WO2022211946A1 (fr) * 2021-03-30 2022-10-06 The Alfred E. Mann Foundation For Scientific Research Fils d'électrode ayant des gaines de nerf et systèmes associés
US11491324B2 (en) 2019-10-16 2022-11-08 Invicta Medical, Inc. Adjustable devices for treating sleep apnea, and associated systems and methods
US11617888B2 (en) * 2020-11-04 2023-04-04 Invicta Medical, Inc. Implantable electrodes with remote power delivery for treating sleep apnea, and associated systems and methods
US11623086B2 (en) 2020-01-24 2023-04-11 Medtronic Xomed, Inc. System and method for therapy
US11666755B2 (en) 2020-01-24 2023-06-06 Medtronic Xomed, Inc. System and method for therapy
US11738197B2 (en) 2019-07-25 2023-08-29 Inspire Medical Systems, Inc. Systems and methods for operating an implantable medical device based upon sensed posture information
US11833348B2 (en) 2021-07-09 2023-12-05 The Alfred E. Mann Foundation For Scientific Research Electrode leads having multi-application helical nerve cuffs and associated systems and methods
US11964154B1 (en) 2023-06-07 2024-04-23 Invicta Medical, Inc. Signal delivery devices to treat sleep apnea, and associated methods and systems

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EP3432975B1 (fr) 2016-03-21 2024-02-14 Nalu Medical, Inc. Dispositifs de positionnement de dispositifs externes par rapport à des dispositifs implantés
US11247039B2 (en) 2016-05-03 2022-02-15 Btl Healthcare Technologies A.S. Device including RF source of energy and vacuum system
US10583287B2 (en) 2016-05-23 2020-03-10 Btl Medical Technologies S.R.O. Systems and methods for tissue treatment
US10556122B1 (en) 2016-07-01 2020-02-11 Btl Medical Technologies S.R.O. Aesthetic method of biological structure treatment by magnetic field
EP3484577A4 (fr) 2016-07-18 2020-03-25 Nalu Medical, Inc. Procédés et systèmes de traitement de troubles pelviens et d'affections douloureuses
EP3585475B1 (fr) 2017-02-24 2024-04-03 Nalu Medical, Inc. Appareil avec stimulateurs implantés séquentiellement
JP2021518249A (ja) 2018-03-20 2021-08-02 セカンド・ハート・アシスト・インコーポレイテッド 循環補助ポンプ
BR112022022112A2 (pt) 2020-05-04 2022-12-13 Btl Healthcare Tech A S Dispositivo para tratamento não assistido do paciente
US11878167B2 (en) 2020-05-04 2024-01-23 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
AU2021296809A1 (en) * 2020-06-22 2023-02-02 Nalu Medical, Inc. Stimulation energy systems with current steering
US11896816B2 (en) 2021-11-03 2024-02-13 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
WO2024020233A1 (fr) * 2022-07-22 2024-01-25 RBI Medical Système et procédé de stimulation nerveuse

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Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11324950B2 (en) 2016-04-19 2022-05-10 Inspire Medical Systems, Inc. Accelerometer-based sensing for sleep disordered breathing (SDB) care
US11298540B2 (en) 2017-08-11 2022-04-12 Inspire Medical Systems, Inc. Cuff electrode
US11975197B2 (en) 2017-08-11 2024-05-07 Inspire Medical Systems, Inc. Cuff electrode
US11266837B2 (en) 2019-03-06 2022-03-08 Medtronic Xomed, Inc. Position sensitive lingual muscle simulation system for obstructive sleep apnea
WO2020181123A1 (fr) * 2019-03-06 2020-09-10 Medtronic Xomed, LLC Système de simulation de muscle lingual sensible à la position pour apnée obstructive du sommeil
US11738197B2 (en) 2019-07-25 2023-08-29 Inspire Medical Systems, Inc. Systems and methods for operating an implantable medical device based upon sensed posture information
US11491324B2 (en) 2019-10-16 2022-11-08 Invicta Medical, Inc. Adjustable devices for treating sleep apnea, and associated systems and methods
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US20210038889A1 (en) 2021-02-11
AU2018215194B2 (en) 2023-02-02
US20200206501A1 (en) 2020-07-02
US11638826B2 (en) 2023-05-02
US20230241393A1 (en) 2023-08-03
WO2018144631A1 (fr) 2018-08-09
CA3071628A1 (fr) 2018-08-09
US11654284B2 (en) 2023-05-23
EP3576838A1 (fr) 2019-12-11
US20210052893A1 (en) 2021-02-25
AU2018215194A1 (en) 2019-08-15
US11642529B2 (en) 2023-05-09
US20200368526A1 (en) 2020-11-26
US20190143110A1 (en) 2019-05-16

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