US20110160827A1 - Electrode lead system - Google Patents
Electrode lead system Download PDFInfo
- Publication number
- US20110160827A1 US20110160827A1 US12/990,705 US99070509A US2011160827A1 US 20110160827 A1 US20110160827 A1 US 20110160827A1 US 99070509 A US99070509 A US 99070509A US 2011160827 A1 US2011160827 A1 US 2011160827A1
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- United States
- Prior art keywords
- lead
- nerve
- lead portion
- cuff
- anchor
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
- A61N1/0556—Cuff electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
- A61N1/0558—Anchoring or fixation means therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
Definitions
- the present disclosure relates generally to an implantable stimulation system for stimulating and monitoring soft tissue in a patient, and more particularly, the present disclosure relates to a lead system for positioning an electrode and lead body of an implantable stimulation system within a body.
- Sleep apnea generally refers to the cessation of breathing during sleep.
- One type of sleep apnea referred to as obstructive sleep apnea (OSA)
- OSA obstructive sleep apnea
- One treatment for obstructive sleep apnea has included the delivery of electrical stimulation to the hypoglossal nerve, located in the neck region under the chin.
- Such stimulation therapy activates the upper airway muscles to maintain upper airway patency.
- increased respiratory effort resulting from the difficulty in breathing through an obstructed airway is avoided by synchronized stimulation of an upper airway muscle or muscle group that holds the airway open during the inspiratory phase of breathing.
- the genioglossus muscle is stimulated during treatment of sleep apnea by a cuff electrode place around the hypoglossal nerve.
- a related challenge in maintaining the proper positioning of the electrode includes making a proper placement of a lead body that extends from the electrode to an implantable pulse generator, which is typically located in the pectoral region of the patient.
- FIG. 1 is a schematic diagram of an implantable stimulation system, according to an embodiment of the present disclosure
- FIG. 2 is a side view of a lead system utilized in an implantable stimulation system, according to an embodiment of the present disclosure
- FIG. 3 is a perspective view of an expandable cuff electrode, according to an embodiment of the present disclosure.
- FIG. 4 is a sectional view of the cuff electrode as taken along lines 4 - 4 of FIG. 3 , according to an embodiment of the present disclosure
- FIG. 5 is a sectional view of an expandable electrode cuff in a larger diameter, fully engaged position, according to an embodiment of the present disclosure
- FIG. 6 is a side plan view of a lead assembly including a cuff electrode and a lead body, according to an embodiment of the present disclosure.
- FIG. 7 is plan view schematically illustrating deployment of the lead assembly of FIG. 6 , according to an embodiment of the present disclosure.
- Embodiments of the present disclosure provide a lead system including a cuff electrode configured to be secured on a nerve and a lead body extending from the cuff electrode to connect with an implantable pulse generator located remotely from the location of the nerve.
- the lead body includes a first lead portion, an anchor, and a second lead portion.
- the anchor is secured relative to a non-nerve anatomical structure, such as a tendon, in close proximity to the location of the cuff electrode on the nerve.
- the first lead body is configured with a length substantially greater than a distance between the secured cuff electrode and the secured anchor.
- the first lead portion includes a generally serpentine configuration formed of a resilient material.
- a strain relief mechanism is established to prevent the cuff electrode from being dislodged from the nerve, or from placing undue stress on the nerve, on the cuff electrode, and/or on the lead body.
- FIGS. 1-7 These embodiments, and other embodiments, will be described in association with FIGS. 1-7 .
- FIG. 1 is a schematic diagram of an implantable stimulation system 12 , according to an embodiment of the present disclosure.
- an example of an implantable stimulation system 12 includes an implantable pulse generator (IPG) 55 , capable of being surgically positioned within a pectoral region of a patient 10 , and a stimulation lead 52 electrically coupled with the IPG 55 via a connector (not shown) positioned within a connection port of the IPG 55 .
- the lead 52 includes an electrode or electrode system 65 and extends from the IPG 55 so that the electrode system 65 is position around a desired nerve, such as the hypoglossal nerve 53 of the patient 10 , to enable stimulation of the nerve 53 , as described below in detail.
- FIG. 1 An exemplary implantable stimulation system in which lead 52 may be utilized, for example, is described in U.S. Pat. No. 6,572,543 to Christopherson et al., incorporated herein by reference in its entirety, and further includes a sensor lead 57 electrically coupled to the IPG 55 and extending from the IPG 55 so that a sensor or transducer 60 can be positioned in the patient 10 for sensing of respiratory effort.
- the sensor 60 may be a pressure sensor that is surgically implanted in a region that has pressure continuity with the intrapleural space, such as the suprasternal notch, the space between the trachea and esophagus, or by being attached to either of the trachea or esophagus.
- the sensor 60 may also be positioned intercostally, or secured in a position for sensing pressure at the posterior side of the manubrium.
- the suprasternal notch 62 and manubrium 63 of the sternum 64 are well known structures on the upper chest that are in anatomical continuity with the intrapleural space. It is also well known that changes in intrapleural pressure provide a characteristic respiratory effort waveform.
- the location for placement of the sensor 60 is, at least in part, chosen as a function of a delay, i.e. the propagation time associated with a pressure waveform characteristic of respiratory effort propagating from the respiratory point of origin to the sensor position.
- the chosen location is also a function of the amount of filtering necessary to achieve a usable sensed signal at a particular location, i.e. the amount of filtering that is necessary to remove waveforms other than the waveform associated with the desired sensed characteristic, such as the filtering required to remove cardiac waveform activity, for example.
- the positioning of the sensor 60 enables the IPG 55 to receive respiratory effort waveform information utilized to determine increased respiratory effort, which is then used by the IPG 55 to control delivery of therapy in response to determined increases in respiratory effort.
- FIG. 2 is a side view of a lead system 80 utilized in the implantable stimulation system, according to an embodiment of the present disclosure, with lead system 80 being used in place of lead 52 of FIG. 1 .
- the lead system 80 includes a lead body 82 , connector 88 , and an expandable cuff electrode 90 .
- the lead body 82 extends from a proximal end 84 to a distal end 86 , with the connector 88 being positioned at the proximal end 84 of the lead body 82 for electrically connecting the lead body 82 to the IPG 55 .
- the expandable electrode cuff 90 is located at the distal end 86 of the lead body 82 and is configured to be positioned around a target nerve, such as a hypoglossal nerve or other nerve.
- the electrode cuff 90 includes one or more electrodes 92 embedded within a wall of the electrode cuff 90 so that when the electrode cuff 90 is positioned around the nerve, the respective electrodes 92 are in contact with the nerve.
- the lead body 82 includes conductors (not shown) extending within the lead body 82 to electrically connect the electrodes 92 and the connector 88 so that the electrodes 92 are electrically coupled to the IPG 55 via respective connector pins 94 of the connector 88 , as is known in the art.
- FIG. 3 is a perspective view of an expandable electrode cuff 100 , according to one embodiment of the present disclosure, which can be deployed in place of the cuff electrode 90 in lead system 80 .
- cuff 100 includes a cuff body 101 and an array 102 of electrodes 103 .
- the cuff body 101 defines a lumen 140 through which a target nerve will extend.
- the cuff body 101 includes a pair of resilient fingers 134 , 150 (e.g., flange members) that have a generally arcuate shape and that extend from a base portion 120 of cuff body 101 .
- the cuff body 101 resumes the shape illustrated in FIG. 3 .
- the materials and construction of the fingers 134 , 150 permit automatic expansion of the size of lumen 140 to accommodate expansion of the size of the nerve encircled by the cuff body 101 .
- the electrodes 103 are held in close contact against the nerve while allowing for expansion of a diameter of lumen 140 defined between fingers 134 , 150 and base 120 .
- the array 102 of electrodes 103 are embedded within a wall of the cuff body 101 with the respective electrodes 103 spaced apart from each other along a length of the cuff body 101 .
- the electrodes 103 are aligned in series along a single longitudinal axis on a common side or portion of the cuff body 101 .
- cuff 100 additionally includes an outer flap or flange member that is biased and configured to maintain releasable coverage of at least a portion of an outer surface of the cuff body 101 and of the re-closable opening 109 between the distal ends of fingers 134 , 150 , as will be described in more detail in association with at least FIGS. 4-5 .
- this outer flap is omitted.
- FIG. 3 illustrates cuff body 101 without an outer flap for illustrative clarity in viewing the features and attributes of cuff body 101 that would otherwise be obscured by the presence of an outer flap.
- FIG. 4 is a sectional view of the expandable electrode cuff 100 , as taken along lines 4 - 4 of FIG. 3 , according to an embodiment of the present disclosure.
- the cuff body 101 of the expandable electrode cuff 100 includes a base portion 120 , a first flange member 130 , a second flange member 134 , and a third flange member 150 .
- FIG. 4 also illustrates one of the electrodes 103 that is embedded in cuff body 101 , as previously illustrated in FIG. 3 .
- electrode 103 includes a proximal trunk portion 110 , a body portion 111 , and a distal hook portion 112 with the distal hook portion 112 defining a recess 114 that extends between a distal tip portion 115 and body portion 111 .
- the proximal trunk portion 110 extends within, and is embedded within, the base portion 120 of the cuff body 101 while the body portion 111 is embedded within the second flange member 134 to be exposed within lumen 140 .
- the base portion 102 includes a top wall 122 , a bottom wall 124 , a first side wall 126 , and a second side wall 128 .
- the second flange member 134 and the third flange member 150 comprise arcuate shaped fingers that are shaped, biased, and have a length to define a generally circular shaped lumen 140 .
- the second flange member 134 extends generally outward from the second side wall 128 and from the top wall 122 of the base portion 120 with at least a portion of the second flange member 134 being spaced apart from the top wall 122 of the base portion 120 .
- the third flange member 150 extends generally outward from the first side wall 126 and from the top wall 122 of the base portion 120 .
- the first flange member 130 includes a proximal end 131 and a distal end or portion 132 with the proximal end 131 being bonded to the third flange member 150 along a portion of an outer wall 152 of the third flange member 150 .
- the first flange member 130 has a length sufficient to extend about, and be in releasable contact with, the periphery or outer surface of both the third flange member 150 and a majority of a length of the second flange member 134 .
- the first flange member 130 is biased to maintain coverage across the substantially re-closable opening 109 (between the distal ends 136 , 152 of the respective second and third flange members 134 , 150 ).
- the free distal portion (including distal end 132 ) of the first flange member 130 extends in a first direction or orientation opposite to the direction (or orientation) in which the free distal portion (including distal end 136 ) of the second flange member 134 extends.
- each of the distal ends 132 , 136 of the respective first and second flange members 130 , 134 will move in opposite directions upon expansion of the lumen 140 in response to a swollen nerve or during positioning of the cuff 100 about a nerve, as will be further described in association with at least FIG. 5 .
- the electrode cuff 100 During its normal, unbiased state, prior to insertion around the nerve, the electrode cuff 100 is in a fully engaged position (shown in FIG. 4 ). Together, the distal ends 136 , 152 of the respective second and third flange members 134 , 150 form the substantially re-closable opening 109 that provides selective access to lumen 140 and that generally maintains a nerve securely within the lumen 140 , unless affirmative steps are taken to remove the electrode cuff 100 from the nerve.
- the electrode cuff 100 may be either in the fully engaged position of FIG. 5 or in a partially fully engaged position ( FIG. 5 ), which occurs in the event that the cuff automatically expands in size to accommodate a larger sized diameter nerve or a swollen nerve.
- a partially fully engaged position FIG. 5
- the general configuration of the electrode cuff 100 remains generally the same as the fully engaged position except that, because the first flange member 130 is slidably movable relative to the second flange member 134 and because the generally flexible, distal portion of the second flange member 134 permits rotational movement of the second flange member 134 away from the third flange member 150 , the distal end 132 of the first flange member 130 will be positioned along, the outer side wall 146 of the second flange member 134 in a location spaced further away from the second side wall 128 than shown in FIG. 4 .
- the substantially re-closable opening 109 between the distal end 136 of the second flange member 134 and the distal end 152 of the third flange member 150 will at least partially open as a gap between the distal ends 136 , 152 , as shown in FIG. 5 .
- the lumen 140 remains generally closed because the first flange member 130 has a length sufficient to still extend across the gap (in the substantially re-closable opening 109 ) between the respective distal ends 136 , 152 and to extend further over (and in releasable contact with) substantial remaining portions of the second flange member 134 .
- FIG. 6 is a side plan view of a lead system, according to an embodiment of the present disclosure.
- the lead system 200 comprises a cuff electrode 202 , a first lead portion 204 , a second lead portion 208 , an anchor 206 , and a connector 210 .
- the cuff electrode 202 of lead system 850 comprises a cuff electrode having substantially the same features and attributes as the embodiments of cuff electrode 100 , as previously described in association with FIGS. 2-5 .
- the cuff electrode 202 comprises other features and attributes of conventional electrode cuffs.
- the first lead portion 204 extends proximally from the cuff electrode 202 and is formed of a resilient material to have a pre-formed, generally serpentine configuration.
- the second lead portion 208 also is formed of a resilient material to have a pre-formed, generally serpentine configuration.
- the second lead portion 208 has a length substantially greater than a length of the first lead portion 204 .
- the second lead portion 208 has a length about seven times the length of the first lead portion 204 .
- the second lead portion 208 has a length sufficient to extend from the placement location of the cuff electrode 202 at a target nerve (e.g. hypoglossal nerve) to the location of placement of the IPG 55 ( FIG. 1 ) within a pectoral region.
- a target nerve e.g. hypoglossal nerve
- the generally serpentine configuration of the respective first and second lead portions 204 , 208 comprises a generally sinusoidal pattern including a series of S-shaped curves.
- the generally serpentine configuration of the respective first and second lead portions 204 , 208 comprises other undulating or curvaceous shapes and patterns.
- a respective one of the first and second lead portions 204 , 208 has a first type of undulating or curvaceous pattern while the other respective one of the first and second lead portions 204 , 208 have a second, different type of undulating or curvaceous pattern.
- the anchor 206 is interposed between the first lead portion and the second lead portion 208 and is configured to be secured relative to a body structure adjacent to the target nerve on which the cuff electrode 202 is mounted.
- the connector 210 extends proximally from the second lead portion 208 and is configured to electrically connect to an implantable pulse generator (such as IPG 55 in FIG. 1 ). Accordingly, in this embodiment, the first anchor 204 is not accompanied by a second anchor along the lead body.
- the lead system 200 additionally includes a second anchor interposed between the second lead portion 208 and the connector 210 at a location represented by reference numeral 220 (or another location closer to the first anchor 204 ).
- This second anchor is configured to be secured relative to a body structure and is provided to provide strain relief for the lead system relative to the IPG 55 and relative to the first anchor 204 (when it is secured in close proximity to the cuff electrode and nerve).
- FIG. 7 schematically illustrates a method 300 of placing or delivering the lead assembly 850 .
- the method 300 comprises first providing a lead assembly such as lead assembly 200 as previously described in association with FIG. 6 .
- the first lead portion 204 is maneuvered and arranged to extend proximally from the cuff electrode 202 to a non-nerve bodily structure 330 (such as a digastric tendon, other tendon, or bony structure) that is in close proximity to the hypoglossal nerve 310 and through the mylohyoid muscle (not shown).
- a non-nerve bodily structure 330 such as a digastric tendon, other tendon, or bony structure
- the first anchor 206 is secured the anchor (via sutures 333 or other biocompatible fasteners) to the non-nerve bodily structure 330 adjacent the target nerve 310 while maintaining at least a portion 341 of the first lead portion 204 in a generally serpentine or undulating configuration between the cuff electrode 202 and the anchor 206 .
- other portions 340 of the first lead portion 204 are no longer retain their pre-formed generally serpentine shape.
- method 300 includes arranging the secured cuff electrode 202 and the secured anchor 206 in substantially the same vertical plane such that a majority of the first lead portion 204 extends generally perpendicular to the vertical plane. In one aspect, this arrangement helps to provide the strain relief described below in more detail.
- the second lead portion 208 is then maneuvered and arranged to extend proximally from the anchor toward an implantable pulse generator, using tunneling tools as known in the art. Finally, the connector is used to establish electrical communication and mechanical connection to the IPG 55 .
- a substantial length or portion 341 of the first lead portion 204 remains in a serpentine or otherwise undulating configuration to thereby provide strain relief upon relative movement of the nerve 310 and the tendon 330 .
- the first lead portion 204 has an arcuate length (L 1 ) of about three inches and an at-rest, end-to-end length (L 2 ) of about one inch.
- the arcuate length corresponds to the length of the first lead portion 204 from end-to-end if the first lead portion 204 were stretched out to eliminate the curved portions.
- the end-to-end length (L 2 ) corresponds to the length of the first lead portion 204 from its proximal end (at anchor 206 ) to its distal end (at cuff electrode 202 ) without accounting for the length of the curved portions between the respective ends of the first lead portion 204 .
- the first lead portion 204 has other lengths greater or less than the above-described dimensions provided that the selected length is substantially greater than an expected degree of movement or range of motion of the target nerve 310 relative to the adjacent non-nerve anatomical structure 330 .
- the second lead portion 208 has an arcuate length (L 3 ) of about ten to twelve inches (i.e., including the length of the curved portions) and an end-to-end length (i.e., excluding the length of the curved portions) of about seven inches.
- the second lead portion 208 has other lengths greater or less than the above-described dimensions provided that the selected length is sufficiently long to provide compensate for some degree of bodily movement between the point at which anchor 206 is fastened and the location of the IPG 55 ( FIG. 1 ).
- Embodiments of the present disclosure ensure long term, robust deployment of a cuff electrode on a nerve via a lead system.
- this robust engagement is accomplished via placing a relatively long, generally serpentine lead portion between the secured cuff electrode and an anchor secured to a non-nerve anatomical structure close to the cuff electrode and nerve.
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- Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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US12/990,705 US20110160827A1 (en) | 2008-05-02 | 2009-05-01 | Electrode lead system |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US4992708P | 2008-05-02 | 2008-05-02 | |
US12/990,705 US20110160827A1 (en) | 2008-05-02 | 2009-05-01 | Electrode lead system |
PCT/US2009/042546 WO2009135142A1 (fr) | 2008-05-02 | 2009-05-01 | Système de fil d’électrode |
Publications (1)
Publication Number | Publication Date |
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US20110160827A1 true US20110160827A1 (en) | 2011-06-30 |
Family
ID=40852476
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
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US12/990,702 Active 2032-01-12 US9227053B2 (en) | 2008-05-02 | 2009-05-01 | Self expanding electrode cuff |
US12/990,705 Abandoned US20110160827A1 (en) | 2008-05-02 | 2009-05-01 | Electrode lead system |
US14/982,197 Abandoned US20160184581A1 (en) | 2008-05-02 | 2015-12-29 | Self expanding electrode cuff |
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Application Number | Title | Priority Date | Filing Date |
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US12/990,702 Active 2032-01-12 US9227053B2 (en) | 2008-05-02 | 2009-05-01 | Self expanding electrode cuff |
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Application Number | Title | Priority Date | Filing Date |
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US14/982,197 Abandoned US20160184581A1 (en) | 2008-05-02 | 2015-12-29 | Self expanding electrode cuff |
Country Status (7)
Country | Link |
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US (3) | US9227053B2 (fr) |
EP (2) | EP2310084B1 (fr) |
JP (2) | JP5538367B2 (fr) |
CN (2) | CN102202726A (fr) |
AU (2) | AU2009242504A1 (fr) |
CA (2) | CA2722982A1 (fr) |
WO (2) | WO2009135142A1 (fr) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080125827A1 (en) * | 2002-07-24 | 2008-05-29 | Biocontrol Medical Ltd. | Selective nerve fiber stimulation for treating heart conditions |
US20090005845A1 (en) * | 2007-06-26 | 2009-01-01 | Tamir Ben David | Intra-Atrial parasympathetic stimulation |
US20100042186A1 (en) * | 2008-08-13 | 2010-02-18 | Tamir Ben-David | Electrode devices for nerve stimulation and cardiac sensing |
US20110098796A1 (en) * | 2003-05-23 | 2011-04-28 | Tamir Ben-David | Electrode cuffs |
US20110137365A1 (en) * | 2006-09-07 | 2011-06-09 | Bio Control Medical (B.C.M.) Ltd. | Techniques for reducing pain associated with nerve stimulation |
US20120130463A1 (en) * | 2010-11-22 | 2012-05-24 | Tamir Ben-David | Electrode cuff with recesses |
US8494655B2 (en) | 2002-05-23 | 2013-07-23 | Bio Control Medical (B.C.M.) Ltd. | Electrode devices with resistive elements |
US8880192B2 (en) | 2012-04-02 | 2014-11-04 | Bio Control Medical (B.C.M.) Ltd. | Electrode cuffs |
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WO2016149344A1 (fr) | 2015-03-19 | 2016-09-22 | Inspire Medical Systems, Inc. | Stimulation pour le traitement de troubles respiratoires du sommeil |
US20170056466A1 (en) * | 2011-12-21 | 2017-03-02 | Xigen Inflammation Ltd. | Novel JNK inhibitor Molecules for Treatment of Various Diseases |
WO2018045056A1 (fr) * | 2016-08-31 | 2018-03-08 | Medtronic Xomed, Inc. | Système pour surveiller l'intégrité neuronale |
US20180078761A1 (en) * | 2006-10-13 | 2018-03-22 | Cyberonics, Inc. | Obstructive sleep apnea treatment devices, systems and methods |
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US9227053B2 (en) | 2008-05-02 | 2016-01-05 | Medtronic, Inc. | Self expanding electrode cuff |
US8340785B2 (en) | 2008-05-02 | 2012-12-25 | Medtronic, Inc. | Self expanding electrode cuff |
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JP6092212B2 (ja) | 2011-08-11 | 2017-03-08 | インスパイア・メディカル・システムズ・インコーポレイテッドInspire Medical Systems, Inc. | 呼吸努力の検知結果に基づいて刺激プロトコルを選択するためのシステム |
US8934992B2 (en) | 2011-09-01 | 2015-01-13 | Inspire Medical Systems, Inc. | Nerve cuff |
CN103157181B (zh) * | 2011-12-08 | 2015-07-22 | 百多力欧洲股份两合公司 | 可植入的电极引线 |
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WO2016040038A1 (fr) | 2014-09-08 | 2016-03-17 | CARDIONOMIC, Inc. | Procédés de neuromodulation électrique du cœur |
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EP4252833A3 (fr) | 2015-11-17 | 2023-11-15 | Inspire Medical Systems, Inc. | Dispositif de traitement par microstimulation pour les troubles respiratoires du sommeil (sdb) |
DE102016103597A1 (de) * | 2016-02-29 | 2017-08-31 | Albert-Ludwigs-Universität Freiburg | Implantierbare Manschettenelektrode |
CN109310863A (zh) | 2016-03-09 | 2019-02-05 | 卡迪诺米克公司 | 心脏收缩性神经刺激系统和方法 |
US11324950B2 (en) | 2016-04-19 | 2022-05-10 | Inspire Medical Systems, Inc. | Accelerometer-based sensing for sleep disordered breathing (SDB) care |
US20170333692A1 (en) * | 2016-05-23 | 2017-11-23 | Boston Scientific Neuromodulation Corporation | Lead for electrostimulation of a target stimulation region |
EP3509480A4 (fr) * | 2016-09-06 | 2020-04-15 | Axion Biosystems, Inc. | Dispositifs et procédés pour réparer un dommage à un nerf |
FR3059476A1 (fr) * | 2016-11-30 | 2018-06-01 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Dispositif de connexion electrique |
US11478643B2 (en) | 2017-01-10 | 2022-10-25 | Inspire Medical Systems, Inc. | Power element for an implantable medical device |
WO2018144631A1 (fr) * | 2017-02-01 | 2018-08-09 | The Alfred E. Mann Foundation For Scientific Research | Systèmes et procédés associés à un stimulateur pour traitement de l'apnée obstructive du sommeil |
US20180318577A1 (en) * | 2017-05-02 | 2018-11-08 | The Alfred E. Mann Foundation For Scientific Research | Nerve cuff electrode locking mechanism |
US11298540B2 (en) | 2017-08-11 | 2022-04-12 | Inspire Medical Systems, Inc. | Cuff electrode |
WO2019055434A1 (fr) | 2017-09-13 | 2019-03-21 | CARDIONOMIC, Inc. | Systèmes de neurostimulation et procédés pour affecter la contractilité cardiaque |
WO2019071080A1 (fr) | 2017-10-06 | 2019-04-11 | Medtronic Xomed, Inc. | Ensembles électrodes d'enregistrement et de stimulation de tampon |
US10589089B2 (en) | 2017-10-25 | 2020-03-17 | Epineuron Technologies Inc. | Systems and methods for delivering neuroregenerative therapy |
US11247045B2 (en) | 2017-10-25 | 2022-02-15 | Epineuron Technologies Inc. | Systems and methods for delivering neuroregenerative therapy |
JP7086810B2 (ja) | 2017-11-09 | 2022-06-20 | 日本工機株式会社 | 燃焼装置及び炬火装置 |
WO2019110378A1 (fr) * | 2017-12-04 | 2019-06-13 | Synergia Medical | Électrode ou optrode à manchon comprenant des bords souples et procédé de production associé |
US10729342B2 (en) | 2018-02-28 | 2020-08-04 | Medtronic Xomed, Inc. | Nerve monitoring and/or stimulation electrode assemblies |
EP3793666A1 (fr) | 2018-05-12 | 2021-03-24 | Inspire Medical Systems, Inc. | Dispositif médical comprenant une partie de préhension d'outil |
DE102018213120A1 (de) * | 2018-08-06 | 2020-02-06 | Neuroloop GmbH | Medizinisches Implantat in Art einer Wickelmanschetten-Elektrodenanordnung |
CA3107959A1 (fr) | 2018-08-13 | 2020-02-20 | CARDIONOMIC, Inc. | Systemes et procedes pour affecter la contractilite et/ou la relaxation cardiaques |
US20200147376A1 (en) | 2018-11-13 | 2020-05-14 | Inspire Medical Systems, Inc. | Multiple type sleep apnea |
JP2022519297A (ja) | 2019-02-05 | 2022-03-22 | インスパイア・メディカル・システムズ・インコーポレイテッド | 睡眠呼吸障害(sdb)ケアのための移植アクセス切開部および感知 |
WO2020219912A1 (fr) * | 2019-04-24 | 2020-10-29 | Galvani Bioelectronics Limited | Interface neuronale |
EP3965639A4 (fr) | 2019-05-06 | 2022-12-07 | Cardionomic, Inc. | Systèmes et procédés de débruitage de signaux physiologiques pendant une neuromodulation électrique |
WO2020243104A1 (fr) | 2019-05-24 | 2020-12-03 | Inspire Medical Systems, Inc. | Systèmes et procédés de traitement de l'incontinence |
AU2020316105A1 (en) | 2019-07-25 | 2022-03-03 | Inspire Medical Systems, Inc. | Respiration detection |
US20230140863A1 (en) | 2019-07-25 | 2023-05-11 | Inspire Medical Systems, Inc. | Systems and methods for operating an implantable medical device based upon a sensed physical action |
US20230095780A1 (en) | 2019-07-25 | 2023-03-30 | Inspire Medical Systems, Inc. | Sleep detection for sleep disordered breathing (sdb) care |
EP4003497A1 (fr) | 2019-07-25 | 2022-06-01 | Inspire Medical Systems, Inc. | Systèmes et procédés pour faire fonctionner un dispositif médical implantable sur la base d'informations de postures détectées |
US11364381B2 (en) | 2019-10-01 | 2022-06-21 | Epineuron Technologies Inc. | Methods for delivering neuroregenerative therapy and reducing post-operative and chronic pain |
CN112869747B (zh) * | 2019-11-29 | 2022-11-25 | 清华大学 | 微电极及其制作和使用方法、塞类装置和微电极系统 |
EP4285834A3 (fr) | 2020-05-19 | 2023-12-13 | Coravie Medical, Inc. | Systèmes de surveillance hémodynamique injectables |
JP2023526870A (ja) | 2020-05-23 | 2023-06-23 | インスパイア・メディカル・システムズ・インコーポレイテッド | 睡眠呼吸障害を治療するための単一または複数の神経刺激 |
WO2022020489A1 (fr) | 2020-07-24 | 2022-01-27 | Inspire Medical Systems, Inc. | Indication de charge de maladie |
WO2022098786A1 (fr) | 2020-11-04 | 2022-05-12 | Invicta Medical, Inc. | Électrodes implantables à délivrance de puissance à distance pour le traitement de l'apnée du sommeil, ainsi que systèmes et méthodes associés |
US20240139526A1 (en) | 2021-03-04 | 2024-05-02 | Inspire Medical Systems, Inc. | Assemblies and methods for wirelessly interfacing with an implantable medical device |
US20240149064A1 (en) | 2021-03-11 | 2024-05-09 | Inspire Medical Systems, Inc. | Systems and methods for treating bladder and/or bowel dysfunction |
AU2022279294A1 (en) | 2021-05-21 | 2023-12-14 | Inspire Medical Systems, Inc. | Multiple target stimulation therapy for sleep disordered breathing |
EP4351417A1 (fr) | 2021-06-10 | 2024-04-17 | Inspire Medical Systems, Inc. | Détection de respiration |
US11833348B2 (en) | 2021-07-09 | 2023-12-05 | The Alfred E. Mann Foundation For Scientific Research | Electrode leads having multi-application helical nerve cuffs and associated systems and methods |
WO2023043889A2 (fr) * | 2021-09-15 | 2023-03-23 | The Trustees Of Indiana University | Activation et blocage de nerf périphérique à l'aide d'un ensemble manchon et d'un courant alternatif basse fréquence sinusoïdal |
US20240009452A1 (en) * | 2022-07-05 | 2024-01-11 | The Alfred E. Mann Foundation For Scientific Research | Tissue stimulation apparatus and methods of making the same |
Citations (96)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2006600A (en) * | 1932-07-08 | 1935-07-02 | Oesterreichische Dynamit Nobel | Corrosion-resistant and malleable alloy |
US3654933A (en) * | 1968-11-18 | 1972-04-11 | Medtronic Inc | Implatable electrode |
US3774618A (en) * | 1972-07-03 | 1973-11-27 | Avery Labor Inc | Implantable nerve stimulation electrode |
US4044774A (en) * | 1976-02-23 | 1977-08-30 | Medtronic, Inc. | Percutaneously inserted spinal cord stimulation lead |
US4154247A (en) * | 1977-04-01 | 1979-05-15 | Medtronic, Inc. | Formable cardiac pacer lead and method of assembly and attachment to a body organ |
US4374527A (en) * | 1978-07-19 | 1983-02-22 | Medtronic, Inc. | Body stimulation lead |
US4379462A (en) * | 1980-10-29 | 1983-04-12 | Neuromed, Inc. | Multi-electrode catheter assembly for spinal cord stimulation |
US4414986A (en) * | 1982-01-29 | 1983-11-15 | Medtronic, Inc. | Biomedical stimulation lead |
US4512351A (en) * | 1982-11-19 | 1985-04-23 | Cordis Corporation | Percutaneous lead introducing system and method |
US4573481A (en) * | 1984-06-25 | 1986-03-04 | Huntington Institute Of Applied Research | Implantable electrode array |
US4590946A (en) * | 1984-06-14 | 1986-05-27 | Biomed Concepts, Inc. | Surgically implantable electrode for nerve bundles |
US4602624A (en) * | 1984-10-11 | 1986-07-29 | Case Western Reserve University | Implantable cuff, method of manufacture, and method of installation |
US4628614A (en) * | 1983-09-26 | 1986-12-16 | Thompson Stanley P | Flighting for horizontal dryers |
US4649936A (en) * | 1984-10-11 | 1987-03-17 | Case Western Reserve University | Asymmetric single electrode cuff for generation of unidirectionally propagating action potentials for collision blocking |
US4838272A (en) * | 1987-08-19 | 1989-06-13 | The Regents Of The University Of California | Method and apparatus for adaptive closed loop electrical stimulation of muscles |
US4852573A (en) * | 1987-12-04 | 1989-08-01 | Kennedy Philip R | Implantable neural electrode |
US4940065A (en) * | 1989-01-23 | 1990-07-10 | Regents Of The University Of California | Surgically implantable peripheral nerve electrode |
US4967755A (en) * | 1989-02-28 | 1990-11-06 | Medtronic, Inc. | Electromedical lead with pressure sensor |
US5038781A (en) * | 1988-01-21 | 1991-08-13 | Hassan Hamedi | Multi-electrode neurological stimulation apparatus |
US5105826A (en) * | 1990-10-26 | 1992-04-21 | Medtronic, Inc. | Implantable defibrillation electrode and method of manufacture |
US5107856A (en) * | 1991-01-10 | 1992-04-28 | Siemens-Pacesetter, Inc. | Multiple lead suture sleeve |
US5121754A (en) * | 1990-08-21 | 1992-06-16 | Medtronic, Inc. | Lateral displacement percutaneously inserted epidural lead |
US5158080A (en) * | 1990-11-08 | 1992-10-27 | Medtronic, Inc. | Muscle tone |
US5238006A (en) * | 1991-06-24 | 1993-08-24 | Medtronic, Inc. | Apnea stimulation lead |
US5265624A (en) * | 1990-09-06 | 1993-11-30 | Edentec | Stimulation collar |
US5282468A (en) * | 1990-06-07 | 1994-02-01 | Medtronic, Inc. | Implantable neural electrode |
US5324322A (en) * | 1992-04-20 | 1994-06-28 | Case Western Reserve University | Thin film implantable electrode and method of manufacture |
US5344438A (en) * | 1993-04-16 | 1994-09-06 | Medtronic, Inc. | Cuff electrode |
US5351394A (en) * | 1991-05-03 | 1994-10-04 | Cyberonics, Inc. | Method of making a nerve electrode array |
US5398596A (en) * | 1990-07-27 | 1995-03-21 | Nestec S.A. | Extraction device for preparation of a beverage |
US5487756A (en) * | 1994-12-23 | 1996-01-30 | Simon Fraser University | Implantable cuff having improved closure |
US5505201A (en) * | 1994-04-20 | 1996-04-09 | Case Western Reserve University | Implantable helical spiral cuff electrode |
US5531778A (en) * | 1994-09-20 | 1996-07-02 | Cyberonics, Inc. | Circumneural electrode assembly |
US5591216A (en) * | 1995-05-19 | 1997-01-07 | Medtronic, Inc. | Method for treatment of sleep apnea by electrical stimulation |
US5634462A (en) * | 1993-10-15 | 1997-06-03 | Case Western Reserve University | Corrugated inter-fascicular nerve cuff method and apparatus |
US5741319A (en) * | 1995-01-27 | 1998-04-21 | Medtronic, Inc. | Biocompatible medical lead |
US5824027A (en) * | 1997-08-14 | 1998-10-20 | Simon Fraser University | Nerve cuff having one or more isolated chambers |
US5919220A (en) * | 1994-09-16 | 1999-07-06 | Fraunhofer Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. | Cuff electrode |
US5922014A (en) * | 1997-09-02 | 1999-07-13 | Medtronic, Inc. | Single pass lead and method of use |
US5938596A (en) * | 1997-03-17 | 1999-08-17 | Medtronic, Inc. | Medical electrical lead |
US6066195A (en) * | 1998-07-09 | 2000-05-23 | Ko; Ellick Yiu-Cho | Accessory for duct systems |
US6066165A (en) * | 1998-04-30 | 2000-05-23 | Racz; Gabor B | Medical lead with sigma feature |
US6093197A (en) * | 1997-12-08 | 2000-07-25 | Axon Engineering, Inc. | Spiral nerve cuff electrode implantation tool |
US6361494B1 (en) * | 1998-05-18 | 2002-03-26 | Med-El. Elektromedizinische Gerate Ges.M.B.H. | Electrode and method for measuring muscle activity in the pharyngeal airways |
US6366815B1 (en) * | 1997-01-13 | 2002-04-02 | Neurodan A /S | Implantable nerve stimulator electrode |
US6449507B1 (en) * | 1996-04-30 | 2002-09-10 | Medtronic, Inc. | Method and system for nerve stimulation prior to and during a medical procedure |
US20020128700A1 (en) * | 2001-03-08 | 2002-09-12 | Cross Thomas E. | Lead with adjustable angular and spatial relationships between electrodes |
US6456866B1 (en) * | 1999-09-28 | 2002-09-24 | Dustin Tyler | Flat interface nerve electrode and a method for use |
US20030040785A1 (en) * | 2001-08-21 | 2003-02-27 | Maschino Steve E. | Circumneural electrode assembly |
US20040111139A1 (en) * | 2002-12-10 | 2004-06-10 | Mccreery Douglas B. | Apparatus and methods for differential stimulation of nerve fibers |
US20040230278A1 (en) * | 2000-12-29 | 2004-11-18 | Medtronic, Inc. | Bifurcated lead system for a cardiac vein |
US20050010265A1 (en) * | 2003-04-02 | 2005-01-13 | Neurostream Technologies Inc. | Fully implantable nerve signal sensing and stimulation device and method for treating foot drop and other neurological disorders |
US20050096710A1 (en) * | 2003-09-22 | 2005-05-05 | Cvrx, Inc. | Baroreceptor activation for epilepsy control |
US20050113710A1 (en) * | 2003-09-18 | 2005-05-26 | Stahmann Jeffrey E. | Implantable device employing movement sensing for detecting sleep-related disorders |
US6907295B2 (en) * | 2001-08-31 | 2005-06-14 | Biocontrol Medical Ltd. | Electrode assembly for nerve control |
US20060030919A1 (en) * | 2004-08-04 | 2006-02-09 | Ndi Medical, Llc | Devices, systems, and methods employing a molded nerve cuff electrode |
US20060103407A1 (en) * | 2003-12-30 | 2006-05-18 | Intel Corporation | Method and an apparatus for testing transmitter and receiver |
US7054692B1 (en) * | 2001-06-22 | 2006-05-30 | Advanced Bionics Corporation | Fixation device for implantable microdevices |
US7065410B2 (en) * | 2000-09-18 | 2006-06-20 | Cameron Health, Inc. | Subcutaneous electrode with improved contact shape for transthorasic conduction |
US7082336B2 (en) * | 2003-06-04 | 2006-07-25 | Synecor, Llc | Implantable intravascular device for defibrillation and/or pacing |
US20060195170A1 (en) * | 2002-05-23 | 2006-08-31 | Ehud Cohen | Electrode assembly for nerve control |
US20060235484A1 (en) * | 2005-03-14 | 2006-10-19 | Jaax Kristen N | Stimulation of a stimulation site within the neck or head |
US20060266369A1 (en) * | 2005-05-27 | 2006-11-30 | Prospex Medical Ii, Inc. | Devices and methods for treating sleep disorders |
US20060271137A1 (en) * | 2005-05-25 | 2006-11-30 | The Cleveland Clinic Foundation | Apparatus and system to stimulate a nerve |
US20060282127A1 (en) * | 2005-03-24 | 2006-12-14 | Vanderbilt University | Respiratory triggered, bilateral laryngeal stimulator to restore normal ventilation in vocal fold paralysis |
US7160255B2 (en) * | 2001-07-12 | 2007-01-09 | Vahid Saadat | Method and device for sensing and mapping temperature profile of a hollow body organ |
US20070043411A1 (en) * | 2005-08-17 | 2007-02-22 | Enteromedics Inc. | Neural electrode |
US7277749B2 (en) * | 2003-01-15 | 2007-10-02 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Treatments for snoring using injectable neuromuscular stimulators |
US20070233204A1 (en) * | 2006-02-16 | 2007-10-04 | Lima Marcelo G | RFID-based apparatus, system, and method for therapeutic treatment of a patient |
US20070239243A1 (en) * | 2006-03-30 | 2007-10-11 | Advanced Bionics Corporation | Electrode contact configurations for cuff leads |
US20070255379A1 (en) * | 2003-06-04 | 2007-11-01 | Williams Michael S | Intravascular device for neuromodulation |
US20070282209A1 (en) * | 2006-06-02 | 2007-12-06 | Cook Vascular Incorporated | Adjustable tension cuff assembly |
US20070282410A1 (en) * | 2006-04-28 | 2007-12-06 | Cross Thomas E Jr | Implantable medical lead assemblies with improved flexibility and extensibility and having a substantially two-dimensional nature |
US20080091255A1 (en) * | 2006-10-11 | 2008-04-17 | Cardiac Pacemakers | Implantable neurostimulator for modulating cardiovascular function |
US20080103570A1 (en) * | 2006-10-31 | 2008-05-01 | Medtronic, Inc. | Implantable medical elongated member including intermediate fixation |
US20080103545A1 (en) * | 2006-10-13 | 2008-05-01 | Apnex Medical, Inc. | Obstructive sleep apnea treatment devices, systems and methods |
US20080132987A1 (en) * | 2001-04-13 | 2008-06-05 | Greatbatch Ltd. | Medical lead system utilizing electromagnetic bandstop filters |
US7389149B2 (en) * | 2004-06-30 | 2008-06-17 | Cvrx, Inc. | Connection structures for extra-vascular electrode lead body |
US20080172116A1 (en) * | 2007-01-16 | 2008-07-17 | Ndi Medical, Inc. | Devices, systems, and methods employing a molded nerve cuff electrode |
US20080172101A1 (en) * | 2000-09-27 | 2008-07-17 | Cvrx, Inc. | Non-linear electrode array |
US20080208282A1 (en) * | 2007-01-22 | 2008-08-28 | Mark Gelfand | Device and method for the treatment of breathing disorders and cardiac disorders |
US7463934B2 (en) * | 2002-04-12 | 2008-12-09 | Medtronic, Inc. | Implantable medical device with captivation fixation |
US20080319506A1 (en) * | 2007-06-25 | 2008-12-25 | Microtransponder, Inc. | Grooved electrode and wireless microtransponder system |
US20090099439A1 (en) * | 2007-10-16 | 2009-04-16 | Giancarlo Barolat | Surgically implantable electrodes |
US20090210042A1 (en) * | 2008-02-15 | 2009-08-20 | Angeltear Solutions Inc. | Adjustable tissue or nerve cuff and method of use |
US7596414B2 (en) * | 2005-12-05 | 2009-09-29 | Boston Scientific Neuromodulation Corporation | Cuff electrode arrangement for nerve stimulation and methods of treating disorders |
US7634315B2 (en) * | 2007-05-31 | 2009-12-15 | Pacesetter, Inc. | Techniques to monitor and trend nerve damage and recovery |
US20100047376A1 (en) * | 2006-08-29 | 2010-02-25 | Marc-Olivier Imbeau | Nerve cuff injection mold and method of making a nerve cuff |
US20100094379A1 (en) * | 2008-10-09 | 2010-04-15 | Imthera Medical, Inc. | Method of Stimulating a Hypoglossal Nerve for Controlling the Position of a Patient's Tongue |
US7725198B2 (en) * | 2007-04-30 | 2010-05-25 | Medtronic, Inc. | Implantable medical lead assemblies with delivery tether |
US7734350B2 (en) * | 2006-06-14 | 2010-06-08 | Zmed Technologies, Inc. | Respiration apparatus |
US20100145221A1 (en) * | 2008-12-08 | 2010-06-10 | Brunnett William C | Nerve electrode |
US20100174341A1 (en) * | 2008-12-31 | 2010-07-08 | Bolea Stephen L | Obstructive Sleep Apnea Treatment Devices, Systems and Methods |
US20100198103A1 (en) * | 2007-10-09 | 2010-08-05 | Imthera Medical, Inc. | System and method for neural stimulation |
US7787959B1 (en) * | 2006-12-22 | 2010-08-31 | Pacesetter, Inc. | Mechanism and method of attaching a stimulation and/or sensing electrode to a nerve |
US8155757B1 (en) * | 2007-07-26 | 2012-04-10 | Advanced Neuromodulation Systems, Inc. | Cuff electrode having tubular body with controlled closing force |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994000188A1 (fr) * | 1992-06-24 | 1994-01-06 | Cyberonics, Inc. | Traitement de troubles neuropsychiatriques par la stimulation d'un nerf |
WO2000006249A2 (fr) | 1998-07-27 | 2000-02-10 | Case Western Reserve University | Procede et appareil de stimulation en boucle fermee du nerf hypoglosse chez des patients humains en vue de traiter l'apnee obstructive du sommeil |
RU2243790C2 (ru) * | 2000-03-29 | 2005-01-10 | Карашуров Сергей Егорович | Имплантируемый программируемый электростимулятор карашурова с.е. для стимуляции органов и тканей организма |
JP4169460B2 (ja) * | 2000-07-12 | 2008-10-22 | 仁敬 越久 | 体内埋め込み電極 |
US20080177348A1 (en) | 2000-09-27 | 2008-07-24 | Cvrx, Inc. | Electrode contact configurations for an implantable stimulator |
US7499742B2 (en) | 2001-09-26 | 2009-03-03 | Cvrx, Inc. | Electrode structures and methods for their use in cardiovascular reflex control |
JP4469926B2 (ja) * | 2000-09-29 | 2010-06-02 | 学校法人立命館 | カフ型アクチュエータおよびカフ型インタフェース装置 |
AU2002247449B2 (en) | 2001-03-30 | 2006-10-12 | Case Western Reserve University | Systems and methods for selectively stimulating components in, on, or near the pudendal nerve or its branches to achieve selective physiologic responses |
JP2003220420A (ja) | 2002-01-28 | 2003-08-05 | Nippon Steel Corp | 板の成形方法及び成形装置 |
JP4387724B2 (ja) * | 2003-08-12 | 2009-12-24 | テルモ株式会社 | 生体植込み用電極リード |
US7680538B2 (en) | 2005-03-31 | 2010-03-16 | Case Western Reserve University | Method of treating obstructive sleep apnea using electrical nerve stimulation |
US7395119B2 (en) | 2005-05-19 | 2008-07-01 | Cvrx, Inc. | Implantable electrode assembly having reverse electrode configuration |
CN100469401C (zh) * | 2005-10-28 | 2009-03-18 | 清华大学 | 一种植入式神经电脉冲刺激系统 |
US8214056B2 (en) | 2006-06-02 | 2012-07-03 | Neurostream Technologies General Partnership | Nerve cuff, method and apparatus for manufacturing same |
US20100241207A1 (en) | 2006-08-14 | 2010-09-23 | Henry Bluger | Implantable Medical Cuff with Electrode Array |
US8868211B2 (en) | 2006-08-15 | 2014-10-21 | Case Western Reserve University | Nerve cuff for implantable electrode |
US8340785B2 (en) | 2008-05-02 | 2012-12-25 | Medtronic, Inc. | Self expanding electrode cuff |
US9227053B2 (en) | 2008-05-02 | 2016-01-05 | Medtronic, Inc. | Self expanding electrode cuff |
EP3708219B1 (fr) | 2008-05-15 | 2022-08-03 | Inspire Medical Systems, Inc. | Appareil de détection de la pression respiratoire dans un système de stimulation implantable |
EP3714771A1 (fr) | 2008-10-01 | 2020-09-30 | Inspire Medical Systems, Inc. | Système de traitement de l'apnée du sommeil par voie transveineuse |
EP3184045B1 (fr) | 2008-11-19 | 2023-12-06 | Inspire Medical Systems, Inc. | Système de traitement de troubles respiratoires du sommeil |
WO2010117810A1 (fr) | 2009-03-31 | 2010-10-14 | Inspire Medical Systems, Inc. | Accès percutané pour systèmes de traitement de troubles respiratoires du sommeil |
US8585617B2 (en) | 2009-12-21 | 2013-11-19 | Nyxoah SA | Diagnosis and prediction of obstructive sleep apnea |
US10806926B2 (en) | 2009-10-20 | 2020-10-20 | Man & Science Sa | Implantable electrical stimulator |
-
2009
- 2009-05-01 US US12/990,702 patent/US9227053B2/en active Active
- 2009-05-01 JP JP2011507688A patent/JP5538367B2/ja active Active
- 2009-05-01 EP EP09739944.8A patent/EP2310084B1/fr active Active
- 2009-05-01 CN CN2009801256760A patent/CN102202726A/zh active Pending
- 2009-05-01 WO PCT/US2009/042546 patent/WO2009135142A1/fr active Application Filing
- 2009-05-01 AU AU2009242504A patent/AU2009242504A1/en not_active Abandoned
- 2009-05-01 AU AU2009242500A patent/AU2009242500A1/en not_active Abandoned
- 2009-05-01 CA CA2722982A patent/CA2722982A1/fr not_active Abandoned
- 2009-05-01 EP EP09739940.6A patent/EP2310082B1/fr active Active
- 2009-05-01 WO PCT/US2009/042539 patent/WO2009135138A1/fr active Application Filing
- 2009-05-01 US US12/990,705 patent/US20110160827A1/en not_active Abandoned
- 2009-05-01 JP JP2011507685A patent/JP5575113B2/ja active Active
- 2009-05-01 CN CN2009801257161A patent/CN102112177A/zh active Pending
- 2009-05-01 CA CA2722987A patent/CA2722987A1/fr not_active Abandoned
-
2015
- 2015-12-29 US US14/982,197 patent/US20160184581A1/en not_active Abandoned
Patent Citations (101)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2006600A (en) * | 1932-07-08 | 1935-07-02 | Oesterreichische Dynamit Nobel | Corrosion-resistant and malleable alloy |
US3654933A (en) * | 1968-11-18 | 1972-04-11 | Medtronic Inc | Implatable electrode |
US3774618A (en) * | 1972-07-03 | 1973-11-27 | Avery Labor Inc | Implantable nerve stimulation electrode |
US4044774A (en) * | 1976-02-23 | 1977-08-30 | Medtronic, Inc. | Percutaneously inserted spinal cord stimulation lead |
US4154247A (en) * | 1977-04-01 | 1979-05-15 | Medtronic, Inc. | Formable cardiac pacer lead and method of assembly and attachment to a body organ |
US4374527A (en) * | 1978-07-19 | 1983-02-22 | Medtronic, Inc. | Body stimulation lead |
US4379462A (en) * | 1980-10-29 | 1983-04-12 | Neuromed, Inc. | Multi-electrode catheter assembly for spinal cord stimulation |
US4414986A (en) * | 1982-01-29 | 1983-11-15 | Medtronic, Inc. | Biomedical stimulation lead |
US4512351A (en) * | 1982-11-19 | 1985-04-23 | Cordis Corporation | Percutaneous lead introducing system and method |
US4628614A (en) * | 1983-09-26 | 1986-12-16 | Thompson Stanley P | Flighting for horizontal dryers |
US4590946A (en) * | 1984-06-14 | 1986-05-27 | Biomed Concepts, Inc. | Surgically implantable electrode for nerve bundles |
US4573481A (en) * | 1984-06-25 | 1986-03-04 | Huntington Institute Of Applied Research | Implantable electrode array |
US4602624A (en) * | 1984-10-11 | 1986-07-29 | Case Western Reserve University | Implantable cuff, method of manufacture, and method of installation |
US4649936A (en) * | 1984-10-11 | 1987-03-17 | Case Western Reserve University | Asymmetric single electrode cuff for generation of unidirectionally propagating action potentials for collision blocking |
US4838272A (en) * | 1987-08-19 | 1989-06-13 | The Regents Of The University Of California | Method and apparatus for adaptive closed loop electrical stimulation of muscles |
US4852573A (en) * | 1987-12-04 | 1989-08-01 | Kennedy Philip R | Implantable neural electrode |
US5038781A (en) * | 1988-01-21 | 1991-08-13 | Hassan Hamedi | Multi-electrode neurological stimulation apparatus |
US4940065A (en) * | 1989-01-23 | 1990-07-10 | Regents Of The University Of California | Surgically implantable peripheral nerve electrode |
US4967755A (en) * | 1989-02-28 | 1990-11-06 | Medtronic, Inc. | Electromedical lead with pressure sensor |
US5282468A (en) * | 1990-06-07 | 1994-02-01 | Medtronic, Inc. | Implantable neural electrode |
US5398596A (en) * | 1990-07-27 | 1995-03-21 | Nestec S.A. | Extraction device for preparation of a beverage |
US5121754A (en) * | 1990-08-21 | 1992-06-16 | Medtronic, Inc. | Lateral displacement percutaneously inserted epidural lead |
US5265624A (en) * | 1990-09-06 | 1993-11-30 | Edentec | Stimulation collar |
US5105826A (en) * | 1990-10-26 | 1992-04-21 | Medtronic, Inc. | Implantable defibrillation electrode and method of manufacture |
US5158080A (en) * | 1990-11-08 | 1992-10-27 | Medtronic, Inc. | Muscle tone |
US5107856A (en) * | 1991-01-10 | 1992-04-28 | Siemens-Pacesetter, Inc. | Multiple lead suture sleeve |
US5351394A (en) * | 1991-05-03 | 1994-10-04 | Cyberonics, Inc. | Method of making a nerve electrode array |
US5238006A (en) * | 1991-06-24 | 1993-08-24 | Medtronic, Inc. | Apnea stimulation lead |
US5324322A (en) * | 1992-04-20 | 1994-06-28 | Case Western Reserve University | Thin film implantable electrode and method of manufacture |
US5344438A (en) * | 1993-04-16 | 1994-09-06 | Medtronic, Inc. | Cuff electrode |
US5634462A (en) * | 1993-10-15 | 1997-06-03 | Case Western Reserve University | Corrugated inter-fascicular nerve cuff method and apparatus |
US5505201A (en) * | 1994-04-20 | 1996-04-09 | Case Western Reserve University | Implantable helical spiral cuff electrode |
US5919220A (en) * | 1994-09-16 | 1999-07-06 | Fraunhofer Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. | Cuff electrode |
US5531778A (en) * | 1994-09-20 | 1996-07-02 | Cyberonics, Inc. | Circumneural electrode assembly |
US5487756A (en) * | 1994-12-23 | 1996-01-30 | Simon Fraser University | Implantable cuff having improved closure |
US5741319A (en) * | 1995-01-27 | 1998-04-21 | Medtronic, Inc. | Biocompatible medical lead |
US5591216A (en) * | 1995-05-19 | 1997-01-07 | Medtronic, Inc. | Method for treatment of sleep apnea by electrical stimulation |
US6449507B1 (en) * | 1996-04-30 | 2002-09-10 | Medtronic, Inc. | Method and system for nerve stimulation prior to and during a medical procedure |
US6366815B1 (en) * | 1997-01-13 | 2002-04-02 | Neurodan A /S | Implantable nerve stimulator electrode |
US5938596A (en) * | 1997-03-17 | 1999-08-17 | Medtronic, Inc. | Medical electrical lead |
US7248930B1 (en) * | 1997-03-17 | 2007-07-24 | Medtronic, Inc. | Medical electrical lead |
US5824027A (en) * | 1997-08-14 | 1998-10-20 | Simon Fraser University | Nerve cuff having one or more isolated chambers |
US5922014A (en) * | 1997-09-02 | 1999-07-13 | Medtronic, Inc. | Single pass lead and method of use |
US6093197A (en) * | 1997-12-08 | 2000-07-25 | Axon Engineering, Inc. | Spiral nerve cuff electrode implantation tool |
US6066165A (en) * | 1998-04-30 | 2000-05-23 | Racz; Gabor B | Medical lead with sigma feature |
US6361494B1 (en) * | 1998-05-18 | 2002-03-26 | Med-El. Elektromedizinische Gerate Ges.M.B.H. | Electrode and method for measuring muscle activity in the pharyngeal airways |
US6066195A (en) * | 1998-07-09 | 2000-05-23 | Ko; Ellick Yiu-Cho | Accessory for duct systems |
US6456866B1 (en) * | 1999-09-28 | 2002-09-24 | Dustin Tyler | Flat interface nerve electrode and a method for use |
US7065410B2 (en) * | 2000-09-18 | 2006-06-20 | Cameron Health, Inc. | Subcutaneous electrode with improved contact shape for transthorasic conduction |
US20080172101A1 (en) * | 2000-09-27 | 2008-07-17 | Cvrx, Inc. | Non-linear electrode array |
US20040230278A1 (en) * | 2000-12-29 | 2004-11-18 | Medtronic, Inc. | Bifurcated lead system for a cardiac vein |
US20020128700A1 (en) * | 2001-03-08 | 2002-09-12 | Cross Thomas E. | Lead with adjustable angular and spatial relationships between electrodes |
US20080132987A1 (en) * | 2001-04-13 | 2008-06-05 | Greatbatch Ltd. | Medical lead system utilizing electromagnetic bandstop filters |
US7054692B1 (en) * | 2001-06-22 | 2006-05-30 | Advanced Bionics Corporation | Fixation device for implantable microdevices |
US7160255B2 (en) * | 2001-07-12 | 2007-01-09 | Vahid Saadat | Method and device for sensing and mapping temperature profile of a hollow body organ |
US6600956B2 (en) * | 2001-08-21 | 2003-07-29 | Cyberonics, Inc. | Circumneural electrode assembly |
US20030040785A1 (en) * | 2001-08-21 | 2003-02-27 | Maschino Steve E. | Circumneural electrode assembly |
US6907295B2 (en) * | 2001-08-31 | 2005-06-14 | Biocontrol Medical Ltd. | Electrode assembly for nerve control |
US7463934B2 (en) * | 2002-04-12 | 2008-12-09 | Medtronic, Inc. | Implantable medical device with captivation fixation |
US20060195170A1 (en) * | 2002-05-23 | 2006-08-31 | Ehud Cohen | Electrode assembly for nerve control |
US20040111139A1 (en) * | 2002-12-10 | 2004-06-10 | Mccreery Douglas B. | Apparatus and methods for differential stimulation of nerve fibers |
US7277749B2 (en) * | 2003-01-15 | 2007-10-02 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Treatments for snoring using injectable neuromuscular stimulators |
US20050010265A1 (en) * | 2003-04-02 | 2005-01-13 | Neurostream Technologies Inc. | Fully implantable nerve signal sensing and stimulation device and method for treating foot drop and other neurological disorders |
US7082336B2 (en) * | 2003-06-04 | 2006-07-25 | Synecor, Llc | Implantable intravascular device for defibrillation and/or pacing |
US20070255379A1 (en) * | 2003-06-04 | 2007-11-01 | Williams Michael S | Intravascular device for neuromodulation |
US20050113710A1 (en) * | 2003-09-18 | 2005-05-26 | Stahmann Jeffrey E. | Implantable device employing movement sensing for detecting sleep-related disorders |
US20050096710A1 (en) * | 2003-09-22 | 2005-05-05 | Cvrx, Inc. | Baroreceptor activation for epilepsy control |
US20060103407A1 (en) * | 2003-12-30 | 2006-05-18 | Intel Corporation | Method and an apparatus for testing transmitter and receiver |
US7389149B2 (en) * | 2004-06-30 | 2008-06-17 | Cvrx, Inc. | Connection structures for extra-vascular electrode lead body |
US20060030919A1 (en) * | 2004-08-04 | 2006-02-09 | Ndi Medical, Llc | Devices, systems, and methods employing a molded nerve cuff electrode |
US20060235484A1 (en) * | 2005-03-14 | 2006-10-19 | Jaax Kristen N | Stimulation of a stimulation site within the neck or head |
US20060282127A1 (en) * | 2005-03-24 | 2006-12-14 | Vanderbilt University | Respiratory triggered, bilateral laryngeal stimulator to restore normal ventilation in vocal fold paralysis |
US20060271137A1 (en) * | 2005-05-25 | 2006-11-30 | The Cleveland Clinic Foundation | Apparatus and system to stimulate a nerve |
US20060266369A1 (en) * | 2005-05-27 | 2006-11-30 | Prospex Medical Ii, Inc. | Devices and methods for treating sleep disorders |
US7644714B2 (en) * | 2005-05-27 | 2010-01-12 | Apnex Medical, Inc. | Devices and methods for treating sleep disorders |
US20070043411A1 (en) * | 2005-08-17 | 2007-02-22 | Enteromedics Inc. | Neural electrode |
US7596414B2 (en) * | 2005-12-05 | 2009-09-29 | Boston Scientific Neuromodulation Corporation | Cuff electrode arrangement for nerve stimulation and methods of treating disorders |
US7725195B2 (en) * | 2006-02-16 | 2010-05-25 | Imthera Medical, Inc. | RFID-based apparatus, system, and method for therapeutic treatment of obstructive sleep apnea |
US20070233204A1 (en) * | 2006-02-16 | 2007-10-04 | Lima Marcelo G | RFID-based apparatus, system, and method for therapeutic treatment of a patient |
US20070239243A1 (en) * | 2006-03-30 | 2007-10-11 | Advanced Bionics Corporation | Electrode contact configurations for cuff leads |
US20070282410A1 (en) * | 2006-04-28 | 2007-12-06 | Cross Thomas E Jr | Implantable medical lead assemblies with improved flexibility and extensibility and having a substantially two-dimensional nature |
US20070282209A1 (en) * | 2006-06-02 | 2007-12-06 | Cook Vascular Incorporated | Adjustable tension cuff assembly |
US7734350B2 (en) * | 2006-06-14 | 2010-06-08 | Zmed Technologies, Inc. | Respiration apparatus |
US20100047376A1 (en) * | 2006-08-29 | 2010-02-25 | Marc-Olivier Imbeau | Nerve cuff injection mold and method of making a nerve cuff |
US20080091255A1 (en) * | 2006-10-11 | 2008-04-17 | Cardiac Pacemakers | Implantable neurostimulator for modulating cardiovascular function |
US20080103545A1 (en) * | 2006-10-13 | 2008-05-01 | Apnex Medical, Inc. | Obstructive sleep apnea treatment devices, systems and methods |
US20080103570A1 (en) * | 2006-10-31 | 2008-05-01 | Medtronic, Inc. | Implantable medical elongated member including intermediate fixation |
US7787959B1 (en) * | 2006-12-22 | 2010-08-31 | Pacesetter, Inc. | Mechanism and method of attaching a stimulation and/or sensing electrode to a nerve |
US20080172116A1 (en) * | 2007-01-16 | 2008-07-17 | Ndi Medical, Inc. | Devices, systems, and methods employing a molded nerve cuff electrode |
US20080208282A1 (en) * | 2007-01-22 | 2008-08-28 | Mark Gelfand | Device and method for the treatment of breathing disorders and cardiac disorders |
US7725198B2 (en) * | 2007-04-30 | 2010-05-25 | Medtronic, Inc. | Implantable medical lead assemblies with delivery tether |
US7634315B2 (en) * | 2007-05-31 | 2009-12-15 | Pacesetter, Inc. | Techniques to monitor and trend nerve damage and recovery |
US7630771B2 (en) * | 2007-06-25 | 2009-12-08 | Microtransponder, Inc. | Grooved electrode and wireless microtransponder system |
US20080319506A1 (en) * | 2007-06-25 | 2008-12-25 | Microtransponder, Inc. | Grooved electrode and wireless microtransponder system |
US8155757B1 (en) * | 2007-07-26 | 2012-04-10 | Advanced Neuromodulation Systems, Inc. | Cuff electrode having tubular body with controlled closing force |
US20100198103A1 (en) * | 2007-10-09 | 2010-08-05 | Imthera Medical, Inc. | System and method for neural stimulation |
US20090099439A1 (en) * | 2007-10-16 | 2009-04-16 | Giancarlo Barolat | Surgically implantable electrodes |
US20090210042A1 (en) * | 2008-02-15 | 2009-08-20 | Angeltear Solutions Inc. | Adjustable tissue or nerve cuff and method of use |
US20100094379A1 (en) * | 2008-10-09 | 2010-04-15 | Imthera Medical, Inc. | Method of Stimulating a Hypoglossal Nerve for Controlling the Position of a Patient's Tongue |
US20100145221A1 (en) * | 2008-12-08 | 2010-06-10 | Brunnett William C | Nerve electrode |
US20100174341A1 (en) * | 2008-12-31 | 2010-07-08 | Bolea Stephen L | Obstructive Sleep Apnea Treatment Devices, Systems and Methods |
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JP5575113B2 (ja) | 2014-08-20 |
EP2310082B1 (fr) | 2015-10-21 |
EP2310084A1 (fr) | 2011-04-20 |
AU2009242504A1 (en) | 2009-11-05 |
CA2722982A1 (fr) | 2009-11-05 |
JP2011519627A (ja) | 2011-07-14 |
JP2011519630A (ja) | 2011-07-14 |
US9227053B2 (en) | 2016-01-05 |
AU2009242500A1 (en) | 2009-11-05 |
WO2009135142A1 (fr) | 2009-11-05 |
CN102112177A (zh) | 2011-06-29 |
US20110147046A1 (en) | 2011-06-23 |
CN102202726A (zh) | 2011-09-28 |
WO2009135138A1 (fr) | 2009-11-05 |
US20160184581A1 (en) | 2016-06-30 |
EP2310082A1 (fr) | 2011-04-20 |
EP2310084B1 (fr) | 2016-03-23 |
JP5538367B2 (ja) | 2014-07-02 |
CA2722987A1 (fr) | 2009-11-05 |
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