US20100036359A1 - Medical Device Package - Google Patents

Medical Device Package Download PDF

Info

Publication number
US20100036359A1
US20100036359A1 US12/544,435 US54443509A US2010036359A1 US 20100036359 A1 US20100036359 A1 US 20100036359A1 US 54443509 A US54443509 A US 54443509A US 2010036359 A1 US2010036359 A1 US 2010036359A1
Authority
US
United States
Prior art keywords
agents
medical device
agent
device package
container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12/544,435
Inventor
Joshua B. Stopek
Matthew D. Cohen
Joseph Hotter
William Denman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covidien LP
Original Assignee
Tyco Healthcare Group LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tyco Healthcare Group LP filed Critical Tyco Healthcare Group LP
Priority to US12/544,435 priority Critical patent/US20100036359A1/en
Assigned to TYCO HEALTHCARE GROUP LP reassignment TYCO HEALTHCARE GROUP LP ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: DENMAN, WILLIAM, COHEN, MATTHEW D., HOTTER, JOSEPH, STOPEK, JOSHUA B.
Publication of US20100036359A1 publication Critical patent/US20100036359A1/en
Abandoned legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06114Packages or dispensers for needles or sutures
    • A61B17/06133Packages or dispensers for needles or sutures of parallelepipedal shape, e.g. made of rectangular or slightly oval panels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/005Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00526Methods of manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00893Material properties pharmaceutically effective
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06114Packages or dispensers for needles or sutures
    • A61B2017/06142Packages or dispensers for needles or sutures having needle- or suture- retaining members, e.g. holding tabs or needle parks
    • A61B2017/06147Foam blocks, e.g. slitted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06114Packages or dispensers for needles or sutures
    • A61B2017/06152Packages or dispensers for needles or sutures containing a suture wound in a figure-8 configuration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A61B2050/3005Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments containing a preservative liquid, e.g. an antiseptic liquid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices

Definitions

  • the present disclosure relates generally to packaging for medical devices, and more particularly, to a medical device package including a container having an area configured to receive a medical device and an area configured for storing at least one agent and a port for permitting the passage of a contact material between the outside of the container and the area of the container configured for storing the agent.
  • Combination medical devices i.e., medical devices coated with drugs or other bioactive agents
  • these combination medical devices known to those skilled in the art.
  • Many of these devices require specialized coatings to facilitate both bioactive agent elution and, more importantly, maintain or enhance the core fictionally of the medical device.
  • a suture containing an antimicrobial coating must be able to facilitate the elution of the antimicrobial agent in the coating and also maintain a certain tensile strength, handling ability, knot-tying ability, and degradation rate to ensure the coated suture remains functional as a wound closure device.
  • the present disclosure describes a package for a medical device aimed at simplifying the design and application of combination medical device coatings to provide the following benefits: sensitive agents can be delivered without compromising standard storage or transport conditions; the ability to later combine a specific medical device with agents that were unable to tolerate the required sterilization process for that specific device, under sterile conditions; the medical professional has greater control over product selection; and longer shelf-life of products due to more stable format.
  • a package for a medical device in accordance with the present disclosure includes a container for receiving a medical device wherein the container has an area configured for storing at least one agent and a port for permitting the passage of a contact material between the outside of the container and the area of the container configured for storing at least one agent therein.
  • the area configured for storing the agent may be defined within the container or as a separate compartment positioned within or adjacent to the container.
  • a medical device package as described herein may include a container configured for receiving a medical device including a reservoir for storing at least one agent and a port for permitting the passage of a contact material between the outside of the container and the reservoir configured for storing the agent.
  • the reservoir is positioned within the container in a manner capable of applying the agent to at least a portion of the medical device received in the container.
  • the portion of the medical device to be contacted by the agent and/or the contact material may pass through or be positioned within the reservoir.
  • a medical device package in accordance with the present disclosure includes a container for receiving a medical device having at least one separate, self-contained agent and a port for permitting the passage of a contact material between the outside of the container and the self-contained agent. It is envisioned that the contact material will interact with the self-contained agent in any manner suitable for activating and/or releasing the agent stored therein so that the medical device received by the container may come in contact with the agent and/or the contact material.
  • FIG. 1 is a top view of a medical device package described herein, wherein the area configured for storing at least one agent is defined within the container;
  • FIG. 2 is a perspective view of a medical device package described herein, wherein the area configured for storing at least one agent is a compartment defined within a portion of the container;
  • FIG. 3 is a perspective view of a medical device package described herein, wherein at least one separate, self-contained agent is positioned within the container.
  • the medical device packages described herein include a container having an area configured for receiving a medical device, an area configured for storing at least one agent and a port for permitting the passage of a contact material between the outside of the container and the area configured for storing at least one agent.
  • the container may include a single area configured for receiving both the medical device and the agent.
  • any medical device may be stored within the package.
  • Some examples include, but are not limited to, sutures, staples, clips, adhesives, sealants, stents, grafts, meshes, sternum closures, pins, screws, tacks, and adhesion barriers.
  • the container is dimensioned and configured to receive a medical device.
  • the container may be any conventional enclosure for storing medical devices and more than one container may be combined to form the medical device packages described herein.
  • Some examples of useful containers include, but are not limited too, pouches, paper retainers, plastic retainers, bags, trays, envelopes, Tyvek® bags, foil-packs, and the like. It is envisioned that the containers may be sealable, non-sealable, breathable, non-breathable, peelable, resealable, and combinations thereof.
  • the container may be manufactured from any material known to those skilled in the art which is suitable for receiving or storing a medical device.
  • suitable materials include, but are not limited to, polycarbonate, high-density polyethylene, polyethylene, polypropylene, thermoplastic resins, polytetrafluoroethylene, ⁇ -caprolactone, glycolide, 1-lactide, d,1-lactide, d-lactide, meso-lactide, trimethylene carbonate, 4,4-dimethyl-1,3-dioxan-2-one, p-dioxanone, dioxepanone, ⁇ -valerolactone, ⁇ -butyrolactone, ⁇ -decalactone, 2,5-diketomorpholine, pivalolactone, ⁇ , ⁇ -diethylpropiolactone, 6,8-dioxabicyclooctan-7-one, ethylene carbonate, ethylene oxalate, 3-methyl-1,4-dioxan
  • the container includes an area configured for storing at least one agent.
  • the area for storing the agent is positioned within or adjacent to the package and/or the container in a manner which allows the agent to interact with at least a portion of the medical device. It is envisioned that the agent or agents may be stored in the area configured for storing the agent at any time between the manufacturing of the package and the end-use or withdrawal of the medical device. In some embodiments, the area configured for storing the agent may be intended to keep the agent from prematurely reacting with the medical device prior to use by medical personnel or the introduction of the contact material via the port.
  • the area configured for storing the agent may be defined within the container (See FIG. 1 ). In some embodiments, the area configured for storing the agent may be defined within a portion of the container (See FIG. 2 ). In still other embodiments, the container may include at least one separate, self-contained agent positioned anywhere within or adjacent to the container (See FIG. 3 ).
  • the area configured for storing the agent is capable of storing the agent in any suitable form.
  • the agent may be stored as solid, liquid, semi-solid, gas, or any combination thereof.
  • the at least one agent may be selected from any bioactive and/or non-bioactive agent suitable for combination with the medical device.
  • Suitable agents include, but are not limited to, drugs, such as antiseptics, anesthetics, muscle relaxants, antihistamines, decongestants, antimicrobial agents, anti-viral agents, anti-fungal agents, antimalarials, amebicides, antituberculosal agents, antiretroviral agents, leprostatics, antiprotazoals, antihelmitics, antibacterial agents, steroids, hematopoietic agents, antiplatelet agents, anticoagulants, coagulants, thrombolytic agents, hemorrheologic agents, hemostatics, plasma expanders, hormones, sex hormones, uterine-active agents, bisphosphonates, antidiabetic agents, glucose-elevating agents, growth hormones, thyroid hormones, inotropic agents, antiarrhythmic agents, calcium channel blockers, vasodilators, sympatholytics, antihyperlipidemic agents, vasopressors, angiotensin antagonists, sclerosing agents,
  • the package includes a port.
  • the port is designed to permit the passage of at least one diluent between the outside of the container and the area configured for storing the agent. It is envisioned that the port may be any type of port or hub, known to allow the passage of a diluent therethrough.
  • the port may be made of any size, shape or dimension and may be composed of any rubber, gel, metallic, polymeric, or thermoplastic material known to those skilled in the art.
  • the port may also be sealable, non-sealable, resealable, stationary, movable, peelable, self-puncturable and combinations thereof.
  • the port may be positioned along any side, edge or corner of the container.
  • the port may be positioned along any side, edge or corner of any of the containers included in the package.
  • the package may contain more than one port and/or more than container may share a common port.
  • the port may be an injectable-hub, or injection port, which is designed to remain sealed by self-sealing action to ensure no liquid, semi-solid, or gas medium can escape and also so no pathogens can breach the container.
  • the port may be a hub designed in such a way that only a particular injector can mate with the port, i.e., male/female or lock/key type hubs. These types of ports provide more safety to the user of the port because the port does not necessarily require the use of a sharp injector or needle.
  • the contact material is intended to be delivered from outside the container, via the port, to the area configured for storing at least one agent.
  • the contact material may be introduced to initiate or enhance the interaction, penetration, impregnation, or coating of the medical device by the stored agent.
  • the term “contact material” is meant to include any material, i.e., solid, liquid, semi-solid, gas, or combination thereof which interacts with the agent, the medical device, or the container itself.
  • the contact material may be any of the bioactive or non-bioactive agents described herein.
  • contact materials include diluents or wetting agents, such as water, saline, dextrose and lactated ringers.
  • package 10 including container 20 having a single area 40 configured for storing at least one agent and receiving the medical device, and a port 60 for permitting the passage of a contact material between the outside of container 20 and area 40 configured for storing the agent.
  • medical device 30 i.e., a suture
  • Port 60 is positioned on an outer edge of container 20 and is connected to area 40 .
  • an injector may be connected to port 60 to deliver a contact material through port 60 and into area 40 to interact with agent 50 . Since at least a portion of medical device 30 is positioned within area 40 , the contact material and agent 50 may coat, impregnate, react with, or be absorbed by medical device 30 .
  • container 20 includes an area configured for receiving a medical device 25 , an area configured for storing at least one agent 40 and a port 60 .
  • the area configured for storing an agent 40 is shown as a reservoir or compartment positioned within container 20 .
  • the reservoir or compartment may be designed as a hollow chamber configured for storing agent 50 .
  • the reservoir may be used to apply agent 50 to specific portions of medical device 30 .
  • the reservoir may be used to apply agent 50 to at least a portion of medical device 30 as it is withdrawn from container 20 .
  • the reservoir may be detachable or removable from container 20 . It is envisioned that the reservoir is capable of storing from about 0.01 microliters to about 10,000 microliters. In some embodiments, the reservoir 40 does not contain an agent. Rather, an agent or a contact material or both may be added to reservoir 40 via port 60 by the end-user of the medical device immediately prior to withdrawal of the medical device.
  • package 10 is shown including container 20 having an area configured for receiving a medical device 25 , at least one separate, self-contained agent 50 and a port 60 .
  • the self-contained agent is capable of being dissolved, reconstituted, emulsified, suspended, vaporized, melted, and the like, by the contact material to initiate or enhance the interaction, penetration, impregnation, or coating of the medical device.
  • the self-contained agents may take the form of or be stored within capsules, tablets, pellets, particulate matters, pressed powders, organized gels, and the like.
  • the self-contained agents may include materials such as gelatin, polyvinyl alcohols, hydrophilic, hydrophobic, and amphiphilic materials.
  • a pair of self-contained agents 50 in the form of gelatin capsules, will not interact with medical device 30 until the introduction of a contact material via port 60 .
  • Port 60 is capable of permitting the passage of the contact material between the outside of the container and self-contained agents 50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Dentistry (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Surgical Instruments (AREA)
  • Materials For Medical Uses (AREA)
  • Packages (AREA)

Abstract

The present disclosure provides a medical device package including a container for receiving a medical device having an area configured for storing at least one agent and a port for permitting the passage of a contact material between the outside the container and the area configured for storing the agent.

Description

    BACKGROUND
  • 1. Technical Field
  • The present disclosure relates generally to packaging for medical devices, and more particularly, to a medical device package including a container having an area configured to receive a medical device and an area configured for storing at least one agent and a port for permitting the passage of a contact material between the outside of the container and the area of the container configured for storing the agent.
  • 2. Background of Related Art
  • Combination medical devices, i.e., medical devices coated with drugs or other bioactive agents, have become more prevalent commercially in recent years. There are many of these combination medical devices known to those skilled in the art. Many of these devices require specialized coatings to facilitate both bioactive agent elution and, more importantly, maintain or enhance the core fictionally of the medical device. For example, a suture containing an antimicrobial coating must be able to facilitate the elution of the antimicrobial agent in the coating and also maintain a certain tensile strength, handling ability, knot-tying ability, and degradation rate to ensure the coated suture remains functional as a wound closure device.
  • Further, with the selection of a new coating, drug or any combination of medical devices comes the challenge of marrying the selected agents with a coating or medical device that can accommodate both technical requirements described above, as well as the manufacturing, sterilizing, and transporting processes involved in producing such products. This often requires the design of new coating polymers, which are specialized to be compatible with a specific agent, as well as new coating, manufacturing, sterilizing and transporting processes. In addition, designing these new coatings and processes creates the added pressures of possibly impacting the shelf-life of the device as well as the end-use of the combination medical device in a negative manner.
  • Also, medical professionals are limited to using the combination medical device in the dosage and strength produced, without flexibility to alter the product as needed for their respective patients.
  • Therefore, the present disclosure describes a package for a medical device aimed at simplifying the design and application of combination medical device coatings to provide the following benefits: sensitive agents can be delivered without compromising standard storage or transport conditions; the ability to later combine a specific medical device with agents that were unable to tolerate the required sterilization process for that specific device, under sterile conditions; the medical professional has greater control over product selection; and longer shelf-life of products due to more stable format.
  • SUMMARY
  • Accordingly, a package for a medical device in accordance with the present disclosure includes a container for receiving a medical device wherein the container has an area configured for storing at least one agent and a port for permitting the passage of a contact material between the outside of the container and the area of the container configured for storing at least one agent therein. The area configured for storing the agent may be defined within the container or as a separate compartment positioned within or adjacent to the container.
  • In another embodiment, a medical device package as described herein may include a container configured for receiving a medical device including a reservoir for storing at least one agent and a port for permitting the passage of a contact material between the outside of the container and the reservoir configured for storing the agent. The reservoir is positioned within the container in a manner capable of applying the agent to at least a portion of the medical device received in the container. The portion of the medical device to be contacted by the agent and/or the contact material may pass through or be positioned within the reservoir.
  • In still another embodiment, a medical device package in accordance with the present disclosure includes a container for receiving a medical device having at least one separate, self-contained agent and a port for permitting the passage of a contact material between the outside of the container and the self-contained agent. It is envisioned that the contact material will interact with the self-contained agent in any manner suitable for activating and/or releasing the agent stored therein so that the medical device received by the container may come in contact with the agent and/or the contact material.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • Various embodiments are described herein with reference to the drawings wherein:
  • FIG. 1 is a top view of a medical device package described herein, wherein the area configured for storing at least one agent is defined within the container;
  • FIG. 2 is a perspective view of a medical device package described herein, wherein the area configured for storing at least one agent is a compartment defined within a portion of the container; and
  • FIG. 3 is a perspective view of a medical device package described herein, wherein at least one separate, self-contained agent is positioned within the container.
  • DETAILED DESCRIPTION
  • The medical device packages described herein include a container having an area configured for receiving a medical device, an area configured for storing at least one agent and a port for permitting the passage of a contact material between the outside of the container and the area configured for storing at least one agent. In some embodiments, the container may include a single area configured for receiving both the medical device and the agent.
  • It is envisioned that any medical device may be stored within the package. Some examples include, but are not limited to, sutures, staples, clips, adhesives, sealants, stents, grafts, meshes, sternum closures, pins, screws, tacks, and adhesion barriers.
  • The container is dimensioned and configured to receive a medical device. The container may be any conventional enclosure for storing medical devices and more than one container may be combined to form the medical device packages described herein. Some examples of useful containers include, but are not limited too, pouches, paper retainers, plastic retainers, bags, trays, envelopes, Tyvek® bags, foil-packs, and the like. It is envisioned that the containers may be sealable, non-sealable, breathable, non-breathable, peelable, resealable, and combinations thereof.
  • The container may be manufactured from any material known to those skilled in the art which is suitable for receiving or storing a medical device. Some examples of suitable materials include, but are not limited to, polycarbonate, high-density polyethylene, polyethylene, polypropylene, thermoplastic resins, polytetrafluoroethylene, ε-caprolactone, glycolide, 1-lactide, d,1-lactide, d-lactide, meso-lactide, trimethylene carbonate, 4,4-dimethyl-1,3-dioxan-2-one, p-dioxanone, dioxepanone, δ-valerolactone, β-butyrolactone, ε-decalactone, 2,5-diketomorpholine, pivalolactone, α,α-diethylpropiolactone, 6,8-dioxabicyclooctan-7-one, ethylene carbonate, ethylene oxalate, 3-methyl-1,4-dioxane-2,5-dione, 3,3-dimethyl-1,4-dioxane-2,5-dione, polyolefins, polysiloxanes, polyalkylene glycols, polyacrylates, aminoalkyl acrylates, polyvinylalcohols, polyvinylpyrrolidones, polyoxyethylenes, polyacrylamides, poly(2-hydroxy-ethylmethacrylate), polymethacrylamide, dextran, alginic acid, sodium alginate, polysaccharides, gelatin and copolymers, homopolymers, and block copolymers thereof.
  • As further described herein, the container includes an area configured for storing at least one agent. The area for storing the agent is positioned within or adjacent to the package and/or the container in a manner which allows the agent to interact with at least a portion of the medical device. It is envisioned that the agent or agents may be stored in the area configured for storing the agent at any time between the manufacturing of the package and the end-use or withdrawal of the medical device. In some embodiments, the area configured for storing the agent may be intended to keep the agent from prematurely reacting with the medical device prior to use by medical personnel or the introduction of the contact material via the port.
  • In some embodiments, the area configured for storing the agent may be defined within the container (See FIG. 1). In some embodiments, the area configured for storing the agent may be defined within a portion of the container (See FIG. 2). In still other embodiments, the container may include at least one separate, self-contained agent positioned anywhere within or adjacent to the container (See FIG. 3).
  • The area configured for storing the agent is capable of storing the agent in any suitable form. The agent may be stored as solid, liquid, semi-solid, gas, or any combination thereof. The at least one agent may be selected from any bioactive and/or non-bioactive agent suitable for combination with the medical device. Suitable agents include, but are not limited to, drugs, such as antiseptics, anesthetics, muscle relaxants, antihistamines, decongestants, antimicrobial agents, anti-viral agents, anti-fungal agents, antimalarials, amebicides, antituberculosal agents, antiretroviral agents, leprostatics, antiprotazoals, antihelmitics, antibacterial agents, steroids, hematopoietic agents, antiplatelet agents, anticoagulants, coagulants, thrombolytic agents, hemorrheologic agents, hemostatics, plasma expanders, hormones, sex hormones, uterine-active agents, bisphosphonates, antidiabetic agents, glucose-elevating agents, growth hormones, thyroid hormones, inotropic agents, antiarrhythmic agents, calcium channel blockers, vasodilators, sympatholytics, antihyperlipidemic agents, vasopressors, angiotensin antagonists, sclerosing agents, anti-impotence agents, urinary alkanizers, urinary acidifiers, anticholinergics, diuretics, bronchodilators, surfactants, antidepressants, antipsychotics, antianxiety agents, sedatives, hypnotics, barbiturates, antiemetic agents, analgesics, stimulants, anticonvulsants, antiparkinson agents, proton pump inhibitors, H2-antagonists, antispasmodics, laxatives, antidiarrheals, antiflatulents, digestive enzymes, gallstone solubilizing agents, antihypertensive agents, cholesterol-lowering agents, radiopaque agents, immune globulins, monoclonal antibodies, antibodies, antitoxins, antivenins, immunologic agents, anti-inflammatory agents, antineoplastic agents, alkylating agents, antimetabolites, antimitotic agents, radiopharmaceuticals, vitamins, herbs, trace elements, amino acids, enzymes, chelating agents, immunomodulatory agents and immunosuppressive agents; coating materials such as lubricants, and non-bioabsorbable substances such as silicone, beeswax, or polytetrafluoroethylene, as well as absorbable substances such as collagen, chitosan, chitin, carboxymethylcellulose, and homopolymers and/or copolymers of polyalkylene glycols, and higher fatty acids or salts or esters thereof, glycolic acid, a glycolide, lactic acid, a lactide, p-dioxanone, valerolactone and other lactones derived from linear aliphatic hydroxycarboxylic acids, α-hydroxybutyric acid, ethylene carbonate, ethylene oxide, propylene oxide, propylene carbonate, malic acid ester lactones, succinic acid, adipic acid and other linear aliphatic dicarboxylic acids, and linear aliphatic diols such as butanediol and hexanediol; wound healing agents; adhesives; sealants; blood products; blood components; preservatives; colorants; dyes; ultraviolet absorbers; ultraviolet stabilizers; photochromic agents; anti-adhesives; proteins; polysaccharides; peptides; genetic material; viral vectors; nucleic acids; nucleotides; plasmids; lymphokines; radioactive agents; metals; alloys; salts; growth factors; growth factor antagonists; cells; hydrophobic agents; hydrophilic agents; immunological agents; anti-colonization agents; diagnostic agents; imaging agents; diluents, such as water, saline, dextrose; and combinations thereof.
  • In addition to the container and the area configured for storing at least one agent, the package includes a port. The port is designed to permit the passage of at least one diluent between the outside of the container and the area configured for storing the agent. It is envisioned that the port may be any type of port or hub, known to allow the passage of a diluent therethrough. The port may be made of any size, shape or dimension and may be composed of any rubber, gel, metallic, polymeric, or thermoplastic material known to those skilled in the art. The port may also be sealable, non-sealable, resealable, stationary, movable, peelable, self-puncturable and combinations thereof.
  • The port may be positioned along any side, edge or corner of the container. In embodiments wherein the package includes more than one container, the port may be positioned along any side, edge or corner of any of the containers included in the package. In addition, the package may contain more than one port and/or more than container may share a common port.
  • In some embodiments, the port may be an injectable-hub, or injection port, which is designed to remain sealed by self-sealing action to ensure no liquid, semi-solid, or gas medium can escape and also so no pathogens can breach the container. In some embodiments, the port may be a hub designed in such a way that only a particular injector can mate with the port, i.e., male/female or lock/key type hubs. These types of ports provide more safety to the user of the port because the port does not necessarily require the use of a sharp injector or needle.
  • The contact material is intended to be delivered from outside the container, via the port, to the area configured for storing at least one agent. In embodiments where the container includes at least one agent, the contact material may be introduced to initiate or enhance the interaction, penetration, impregnation, or coating of the medical device by the stored agent. The term “contact material” is meant to include any material, i.e., solid, liquid, semi-solid, gas, or combination thereof which interacts with the agent, the medical device, or the container itself. In some embodiments, the contact material may be any of the bioactive or non-bioactive agents described herein. In particularly useful embodiments, contact materials include diluents or wetting agents, such as water, saline, dextrose and lactated ringers.
  • Turning now to FIG. 1, package 10 is shown including container 20 having a single area 40 configured for storing at least one agent and receiving the medical device, and a port 60 for permitting the passage of a contact material between the outside of container 20 and area 40 configured for storing the agent. In some embodiments, at least a portion of medical device 30, i.e., a suture, may be in contact or coated with an agent 50 prior to be received and stored within container 20. Port 60 is positioned on an outer edge of container 20 and is connected to area 40. It is envisioned that an injector may be connected to port 60 to deliver a contact material through port 60 and into area 40 to interact with agent 50. Since at least a portion of medical device 30 is positioned within area 40, the contact material and agent 50 may coat, impregnate, react with, or be absorbed by medical device 30.
  • In another embodiment, as shown in FIG. 2, container 20 includes an area configured for receiving a medical device 25, an area configured for storing at least one agent 40 and a port 60. The area configured for storing an agent 40 is shown as a reservoir or compartment positioned within container 20. In some embodiments, the reservoir or compartment may be designed as a hollow chamber configured for storing agent 50. In some other embodiments, the reservoir may be used to apply agent 50 to specific portions of medical device 30. In still other embodiments, the reservoir may be used to apply agent 50 to at least a portion of medical device 30 as it is withdrawn from container 20.
  • It is also envisioned that the reservoir may be detachable or removable from container 20. It is envisioned that the reservoir is capable of storing from about 0.01 microliters to about 10,000 microliters. In some embodiments, the reservoir 40 does not contain an agent. Rather, an agent or a contact material or both may be added to reservoir 40 via port 60 by the end-user of the medical device immediately prior to withdrawal of the medical device.
  • Turning now to FIG. 3, package 10 is shown including container 20 having an area configured for receiving a medical device 25, at least one separate, self-contained agent 50 and a port 60. It is envisioned that the self-contained agent is capable of being dissolved, reconstituted, emulsified, suspended, vaporized, melted, and the like, by the contact material to initiate or enhance the interaction, penetration, impregnation, or coating of the medical device. In some embodiments, the self-contained agents may take the form of or be stored within capsules, tablets, pellets, particulate matters, pressed powders, organized gels, and the like. The self-contained agents may include materials such as gelatin, polyvinyl alcohols, hydrophilic, hydrophobic, and amphiphilic materials. As shown in FIG. 3, a pair of self-contained agents 50, in the form of gelatin capsules, will not interact with medical device 30 until the introduction of a contact material via port 60. Port 60 is capable of permitting the passage of the contact material between the outside of the container and self-contained agents 50 It is well understood that various modifications may be made to the embodiments disclosed herein. Therefore, the above description should not be construed as limiting, but merely as exemplifications of particularly useful embodiments. Those skilled in the art will envision other modifications within the scope and spirit of the claims appended hereto.

Claims (12)

1. A medical device package comprising:
a container having an area configured for receiving a medical device, a reservoir positioned therein for storing at least one agent; and
a port for permitting the passage of a contact material between the outside of the container and the reservoir storing the at least one agent.
2. The medical device package of claim 1 further comprising a medical device selected from the group consisting of sutures, staples, clips, grafts, stents, meshes, sternum closures, pins, screws, tacks, and combinations thereof.
3. The medical device package of claim 1 wherein the medical device is a suture.
4. The medical device package of claim 1 further comprising at least one agent selected from the group consisting of drugs, coating materials, wound healing agents, adhesives, sealants, blood products, blood components, preservatives, colorants, dyes, ultraviolet absorbers, ultraviolet stabilizers, photochromic agents, anti-adhesives, proteins, polysaccharides, peptides, genetic material, viral vectors, nucleic acids, nucleotides, plasmids, lymphokines, radioactive agents, metals, alloys, salts, growth factors, growth factor antagonists, cells, hydrophobic agents, hydrophilic agents, immunological agents, anti-colonization agents, diagnostic agents, imaging agents, radiopaque agents, and combinations thereof.
5. The medical device package of claim 4 wherein the at least one agent is a drug.
6. The medical device package of claim 5 wherein the drug is selected from the group consisting of antiseptics, anesthetics, muscle relaxants, antihistamines, decongestants, antimicrobial agents, anti-viral agents, anti-fungal agents, antimatarials, amebicides, antituberculosal agents, antiretroviral agents, leprostatics, antiprotazoals, antihelmitics, antibacterial agents, steroids, hematopoietic agents, antiplatelet agents, anticoagulants, coagulants, thrombolytic agents, hemorrheologic agents, hemostatics, plasma expanders, hormones, sex hormones, uterine-active agents, bisphosphonates, antidiabetic agents, glucose-elevating agents, growth hormones, thyroid hormones, inotropic agents, antiarrhythmic agents, calcium channel blockers, vasodilators, sympatholytics, antihyperlipidemic agents, vasopressors, angiotensin antagonists, sclerosing agents, anti-impotence agents, urinary alkanizers, urinary acidifiers, anticholinergics, diuretics, bronchodilators, surfactants, antidepressants, antipsychotics, antianxiety agents, sedatives, hypnotics, barbiturates, antiemetic agents, analgesics, stimulants, anticonvulsants, antiparkinson agents, proton pump inhibitors, H.sub.2-antagonists, antispasmodics, laxatives, antidiarrheals, antiflatulents, digestive enzymes, gallstone solubilizing agents, antihypertensive agents, cholesterol-lowering agents, radiopaque agents, immune globulins, monoclonal antibodies, antibodies, antitoxins, antivenins, immunologic agents, anti-inflammatory agents, antineoplastic agents, alkylating agents, antimetabolites, antimitotic agents, radiopharmaceuticals, vitamins, herbs, trace elements, amino acids, enzymes, chelating agents, immunomodulatory agents, immunosuppressive agents and combinations thereof.
7. The medical device package of claim 1 wherein the reservoir is removable from the container.
8. The medical device package of claim 2 wherein at least a portion of the medical device is positioned within the reservoir.
9. The medical device package of claim 2 wherein at least a portion of the medical device passes through the reservoir.
10. The medical device package of claim 1 wherein the contact material is water.
11. The medical device package of claim 1 wherein the contact material is saline.
12. The medical device package of claim 1 wherein the port is an injection port.
US12/544,435 2006-10-06 2009-08-20 Medical Device Package Abandoned US20100036359A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/544,435 US20100036359A1 (en) 2006-10-06 2009-08-20 Medical Device Package

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/544,503 US20080171972A1 (en) 2006-10-06 2006-10-06 Medical device package
US12/544,435 US20100036359A1 (en) 2006-10-06 2009-08-20 Medical Device Package

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US11/544,503 Division US20080171972A1 (en) 2006-10-06 2006-10-06 Medical device package

Publications (1)

Publication Number Publication Date
US20100036359A1 true US20100036359A1 (en) 2010-02-11

Family

ID=39283855

Family Applications (3)

Application Number Title Priority Date Filing Date
US11/544,503 Abandoned US20080171972A1 (en) 2006-10-06 2006-10-06 Medical device package
US12/544,444 Active 2028-12-04 US8997978B2 (en) 2006-10-06 2009-08-20 Medical device package
US12/544,435 Abandoned US20100036359A1 (en) 2006-10-06 2009-08-20 Medical Device Package

Family Applications Before (2)

Application Number Title Priority Date Filing Date
US11/544,503 Abandoned US20080171972A1 (en) 2006-10-06 2006-10-06 Medical device package
US12/544,444 Active 2028-12-04 US8997978B2 (en) 2006-10-06 2009-08-20 Medical device package

Country Status (6)

Country Link
US (3) US20080171972A1 (en)
EP (1) EP2079388A4 (en)
JP (1) JP2010505520A (en)
AU (1) AU2007307072A1 (en)
CA (1) CA2662445A1 (en)
WO (1) WO2008045338A2 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060091034A1 (en) * 2002-10-04 2006-05-04 Howard Scalzo Method of preparing an antimicrobial packaged medical device
US20090301033A1 (en) * 2002-10-04 2009-12-10 Ethicon, Inc. Method of preparing a packaged antimicrobial medical device
US8112973B2 (en) 2002-10-04 2012-02-14 Ethicon, Inc. Method of making a packaged antimicrobial suture
US8960422B2 (en) 2002-10-04 2015-02-24 Ethicon, Inc. Packaged antimicrobial medical device and method of preparing same
US9474524B2 (en) 2002-10-04 2016-10-25 Ethicon, Inc. Packaged antimicrobial medical device having improved shelf life and method of preparing same
US10245025B2 (en) 2012-04-06 2019-04-02 Ethicon, Inc. Packaged antimicrobial medical device having improved shelf life and method of preparing same
US11807729B2 (en) 2021-04-14 2023-11-07 Goex Corporation Polyethylene terephthalate-polyethylene naphthalate copolymer extruded sheet suitable for medical device packaging

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090209031A1 (en) * 2006-01-26 2009-08-20 Tyco Healthcare Group Lp Medical device package
CN102076280B (en) 2008-06-24 2014-08-27 生物活性外科公司 Surgical sutures incorporated with stem cells or other bioactive materials
KR20110042107A (en) 2008-08-07 2011-04-22 바이오엑티브 써지컬, 아이엔씨. Stem cell capture and immobilization coatings for medical devices and implants
US8439188B2 (en) * 2009-03-06 2013-05-14 The Cleveland Clinic Foundation Method for storing a bioabsorble medical device
US9421009B1 (en) * 2011-09-27 2016-08-23 A. Jamie Riley Suture delivery system
JP7048118B2 (en) 2017-07-17 2022-04-05 アンテリス テクノロジーズ コーポレイション Sterilization packaging system for catheters
KR20210097162A (en) 2018-11-29 2021-08-06 에디컨인코포레이티드 Operating Room Coating Applicators and Methods
USD958358S1 (en) * 2020-10-07 2022-07-19 Alex McClure Suture kit holder
CN118102984A (en) * 2021-08-13 2024-05-28 爱惜康股份有限公司 Systems, kits and methods for coating suture with pharmaceutical compounds immediately prior to implantation of the suture
KR102577817B1 (en) * 2023-04-20 2023-09-13 오지수 Antibacterial Suture Packaging Kit

Citations (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3648949A (en) * 1968-06-28 1972-03-14 Ethicon Inc Suture package
US4259184A (en) * 1976-08-30 1981-03-31 Arnal Hubert A D Sealed container adapted for medical usage and method of sealing
US4366901A (en) * 1981-02-02 1983-01-04 Medtronic, Inc. In situ rehydrating in sterile packages
US4424898A (en) * 1982-04-08 1984-01-10 Ethicon, Inc. Needle and suture holder and package
US4699271A (en) * 1984-06-14 1987-10-13 Lincoln Jay P Plastic dispensing pack for surgical sutures
US4896767A (en) * 1988-02-09 1990-01-30 Ethicon, Inc. Suture package
US4903826A (en) * 1988-02-09 1990-02-27 EMS Medical Group Ltd., Unit 3 Dispenser for surgical guidewire
US4961498A (en) * 1988-08-24 1990-10-09 Ethicon, Inc. Oval wrap suture package
US4967902A (en) * 1989-09-12 1990-11-06 Ethicon, Inc. One piece channel suture packages
US5024322A (en) * 1990-04-27 1991-06-18 United States Surgical Corporation Armed suture package
US5052551A (en) * 1991-01-31 1991-10-01 Ethicon, Inc. Oval wrap suture package with unequal end radii
US5056658A (en) * 1989-09-12 1991-10-15 Ethicon, Inc. One piece channel suture packages
US5099994A (en) * 1988-08-24 1992-03-31 Ethicon, Inc. Oval wrap suture package
US5131553A (en) * 1990-08-14 1992-07-21 Gordon Geasland Tubular plastic shipping, storage and dispensing container and parts usable therewith
US5131533A (en) * 1991-08-28 1992-07-21 Ethicon, Inc. Needle park
US5165217A (en) * 1989-09-12 1992-11-24 Ethicon, Inc. One piece channel suture packages
US5180053A (en) * 1992-02-28 1993-01-19 Ethicon, Inc. Cantilevered needle park
US5179818A (en) * 1988-08-24 1993-01-19 Ethicon, Inc. Oval wrap suture package
US5192483A (en) * 1991-12-02 1993-03-09 W. L. Gore & Associates, Inc. Method of thermoforming a sheet around a suture needle to form a holder
US5213210A (en) * 1992-02-28 1993-05-25 Ethicon, Inc. Easy-loading suture package
US5222978A (en) * 1987-08-26 1993-06-29 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5228565A (en) * 1992-02-26 1993-07-20 United States Surgical Corporation Package and method of loading for resilient surgical sutures
US5230424A (en) * 1992-06-19 1993-07-27 Ethicon, Inc. Multi-strand suture package and cover-latching element
US5236083A (en) * 1989-09-12 1993-08-17 Ethicon, Inc. One piece channel suture packages
US5246104A (en) * 1989-08-01 1993-09-21 United States Surgical Corporation Molded suture retainer
US5249673A (en) * 1992-02-07 1993-10-05 United States Surgical Corporation Package and method of loading for resilient surgical sutures
US5249671A (en) * 1992-02-07 1993-10-05 United States Surgical Corporation Package and method of loading for resilient surgical sutures
US5263585A (en) * 1992-05-07 1993-11-23 Myriadlase, Inc. Package for an elongated flexible fiber
US5271495A (en) * 1992-04-01 1993-12-21 Ethicon, Inc. Oval wrap suture package with rotary wheel
US5284240A (en) * 1993-01-22 1994-02-08 Ethicon, Inc. No touch suture package
US5342673A (en) * 1993-02-23 1994-08-30 W. L. Gore & Associates, Inc. Sterilizable packaging material
US5350060A (en) * 1993-01-15 1994-09-27 Ethicon, Inc. Procedure kit and package
US5359831A (en) * 1989-08-01 1994-11-01 United States Surgical Corporation Molded suture retainer
US5366081A (en) * 1987-08-26 1994-11-22 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5417036A (en) * 1990-08-13 1995-05-23 United States Surgical Corporation Molded suture retainer
US5433315A (en) * 1992-12-04 1995-07-18 B. Braun Melsungen Ag Suture material pack
US5462162A (en) * 1987-08-26 1995-10-31 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5472081A (en) * 1991-12-02 1995-12-05 W. L. Gore & Associates, Inc. Needle holder for a suture package
US5503266A (en) * 1993-10-15 1996-04-02 United States Surgical Corporation Molded suture retainer with needle park
US5575382A (en) * 1994-12-22 1996-11-19 Ethicon, Inc. Rotary self-winding two-piece ligature package
US5628395A (en) * 1995-06-23 1997-05-13 Ethicon, Inc. Suture tray package having grooved winding surface
US5655652A (en) * 1995-02-10 1997-08-12 Ethicon, Inc. Center dispense suture package
US5669490A (en) * 1995-06-07 1997-09-23 United States Surgical Corporation Suture retainer
US5675961A (en) * 1995-06-06 1997-10-14 Ethicon, Inc. Suture dispenser
US5681740A (en) * 1995-06-05 1997-10-28 Cytotherapeutics, Inc. Apparatus and method for storage and transporation of bioartificial organs
US5733293A (en) * 1996-05-08 1998-03-31 United States Surgical Corporation Disposable loading unit for a vascular suturing instrument
US5788062A (en) * 1994-04-04 1998-08-04 Ethicon, Inc. Suture dispenser
US5887706A (en) * 1997-12-05 1999-03-30 Ethicon, Inc. Fenestrated suture package
US5906273A (en) * 1997-12-05 1999-05-25 Ethicon, Inc. Armed suture package with universal dispensing capability
US5918733A (en) * 1998-04-08 1999-07-06 Ethicon, Inc. Ligating reel package
US5954748A (en) * 1996-07-15 1999-09-21 United States Surgical Corporation Gelatin coated gut suture
US6016905A (en) * 1998-03-06 2000-01-25 United States Surgical Corporation Surgical suture retainer package
US6047815A (en) * 1998-08-31 2000-04-11 Ethicon, Inc. Package for sutures
US6076659A (en) * 1998-01-19 2000-06-20 Ethicon, Inc. Packaging for surgical suture material
US6098796A (en) * 1997-06-10 2000-08-08 Ethicon, Inc. Surgical sutures dispenser and a method of coiling surgical sutures
US6135385A (en) * 1997-10-09 2000-10-24 B. Braun Surgical, S.A. Suture material dispenser
US6135272A (en) * 1999-10-22 2000-10-24 Ethicon, Inc. Package for sutures
US6138440A (en) * 1998-03-06 2000-10-31 United States Surgical Corporation Surgical suture retainer package
US6260699B1 (en) * 1987-08-26 2001-07-17 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US6394269B1 (en) * 2000-09-29 2002-05-28 Ethicon, Inc. Needle package with point guards
US6464071B2 (en) * 1998-12-02 2002-10-15 Ethicon, Inc. Packaging for surgical suture
US6481568B1 (en) * 1999-03-29 2002-11-19 Ethicon, Inc. Labyrinth package for sutures
US6481569B1 (en) * 1999-03-11 2002-11-19 Ethicon, Inc. Needle park and method of use
US6533112B2 (en) * 1999-12-03 2003-03-18 Ethicon, Gmbh Packaging for surgical suture material
US20030059463A1 (en) * 1999-12-07 2003-03-27 Mika Lahtinen Medical device
US20030198666A1 (en) * 2002-01-07 2003-10-23 Richat Abbas Oral insulin therapy
US6644469B2 (en) * 2001-07-11 2003-11-11 Ethicon, Inc. Large needle oval wound plastic suture package
US6648133B1 (en) * 2001-07-18 2003-11-18 Biomet, Inc. Device and method for hydrating and rehydrating orthopedic graft materials
US6807737B1 (en) * 2002-05-21 2004-10-26 Christina K. Davia Ergonomic opener for intravenous bag packaging
US20050167309A1 (en) * 2002-06-04 2005-08-04 Mtf Meditech Franken Gmbh Method and device for wetting a medical implant or transplant
US20050278012A1 (en) * 2004-06-10 2005-12-15 Design & Performance - Cyprus Limited Protected stent delivery system and packaging
US20060029722A1 (en) * 2004-08-04 2006-02-09 Larson Marian L Apparatus for coating medical devices
US20060027467A1 (en) * 2004-08-04 2006-02-09 Ferguson Patrick J Anti-microbial suture material dispenser system
US20060163752A1 (en) * 2004-04-05 2006-07-27 Xingwu Wang Storage assembly
US20060193884A1 (en) * 2004-12-01 2006-08-31 Joshua Stopek Novel biomaterial drug delivery and surface modification compositions

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2197717A (en) * 1937-07-27 1940-04-16 Armour & Co Process of packaging sutures
US2764979A (en) * 1953-04-09 1956-10-02 Henderson Edward Medicament dispensing unit
US3369708A (en) * 1965-09-07 1968-02-20 Lincoln Lab Inc Means for reconstituting a dry biological and for controlled dispensing thereof
US3342326A (en) * 1965-10-22 1967-09-19 Johnson & Johnson Sterile flexible package
US3661250A (en) 1970-05-28 1972-05-09 Data Packaging Corp Reel case with lock
US3768725A (en) * 1971-11-11 1973-10-30 Nat Distillers Chem Corp Breathable, sterilizable and peelable pouch and method of manufacture thereof
US4387727A (en) * 1981-03-30 1983-06-14 Medtronic, Inc. Coaxial service kit
US4423819A (en) * 1981-08-19 1984-01-03 U.S. Clinical Products, Inc. Flexible sterile closure system for containers
US4518684A (en) * 1984-05-17 1985-05-21 Howard Martin Rapid X-ray developing system
US5038938A (en) * 1990-06-28 1991-08-13 Ddj Enterprises, Inc. Disposable sanitary arthorcentesis reservoir
DE4140575A1 (en) * 1991-09-20 1993-03-25 Peter Florjancic DENTAL PRESENT CLEANER
CA2092937A1 (en) 1992-04-01 1993-10-02 Marvin Alpern Oval wrap suture package with rotary wheel
CA2097664C (en) * 1992-07-09 1999-05-04 David L. Brown Package for surgical devices
US5376108A (en) * 1993-05-20 1994-12-27 Telectronics Pacing Systems, Inc. Electrode lead anchoring apparatus and method employing dual suture collars
US5620095A (en) * 1993-06-11 1997-04-15 Minnesota Mining And Manufacturing Company Orthopedic casting material and hermetic package
DE4323266C2 (en) 1993-07-12 1995-08-03 Busak & Luyken Gmbh & Co Sealing arrangement
US5765740A (en) * 1993-12-30 1998-06-16 Ferguson; Patrick J. Suture-material-dispenser system for suture material
EP0728445B1 (en) 1995-02-21 1999-12-22 Ethicon, Inc. Suture package
US5698210A (en) * 1995-03-17 1997-12-16 Lee County Mosquito Control District Controlled delivery compositions and processes for treating organisms in a column of water or on land
DK172941B1 (en) 1996-09-18 1999-10-11 Coloplast As A urinary catheter assembly
US6443949B2 (en) * 1997-03-13 2002-09-03 Biocardia, Inc. Method of drug delivery to interstitial regions of the myocardium
JP2002500917A (en) 1998-01-23 2002-01-15 キュアリス・インコーポレーテッド Double package
WO2001036289A1 (en) 1999-11-17 2001-05-25 Fredrick Michael Coory Piercing cap for a container
JP3670265B2 (en) 2001-06-25 2005-07-13 株式会社塚田メディカル・リサーチ Large saphenous varices treatment device
US20030158598A1 (en) * 2001-09-17 2003-08-21 Control Delivery Systems, Inc. System for sustained-release delivery of anti-inflammatory agents from a coated medical device
FR2831144B3 (en) 2001-10-18 2003-12-12 Laurent Chaude DEVICE FOR OPENING / CLOSING A HERMETIC PACKAGE, IN PARTICULAR FOR THE PRESERVATION OF FOOD PRODUCTS
SE0201330D0 (en) 2002-04-30 2002-04-30 Astra Tech Ab Catheter assembly
ATE405224T1 (en) 2002-06-04 2008-09-15 Mtf Meditech Franken Gmbh METHOD AND DEVICE FOR MOISTURIZING NON-BIOLOGICAL MEDICAL IMPLANT MATERIALS
ES2584606T3 (en) * 2002-10-10 2016-09-28 Ono Pharmaceutical Co., Ltd. Microspheres comprising ONO-1301
DE11175010T1 (en) * 2003-08-08 2016-06-02 Hollister Inc. Steam hydration of a hydrophilic catheter in a package
DE602005027692D1 (en) * 2004-05-11 2011-06-09 Cadbury Adams Usa Llc PACKAGING FOR DISPENSING AND HOLDING OF GLUE-LUBRICATED TISSUE STRIPS
US20080241208A1 (en) * 2005-06-30 2008-10-02 Charles Shanley Methods, Compositions and Devices For Promoting Anglogenesis
US7435423B2 (en) * 2005-10-05 2008-10-14 Cory Collinge Wound treatment medium and method of packaging and use
US20070092398A1 (en) * 2005-10-25 2007-04-26 Mcdonald Duane L Pouch for sterilization of medical products
US20070170080A1 (en) * 2006-01-26 2007-07-26 Joshua Stopek Medical device package

Patent Citations (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3648949A (en) * 1968-06-28 1972-03-14 Ethicon Inc Suture package
US4259184A (en) * 1976-08-30 1981-03-31 Arnal Hubert A D Sealed container adapted for medical usage and method of sealing
US4366901A (en) * 1981-02-02 1983-01-04 Medtronic, Inc. In situ rehydrating in sterile packages
US4424898A (en) * 1982-04-08 1984-01-10 Ethicon, Inc. Needle and suture holder and package
US4699271A (en) * 1984-06-14 1987-10-13 Lincoln Jay P Plastic dispensing pack for surgical sutures
US6260699B1 (en) * 1987-08-26 2001-07-17 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5366081A (en) * 1987-08-26 1994-11-22 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5462162A (en) * 1987-08-26 1995-10-31 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5222978A (en) * 1987-08-26 1993-06-29 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5468252A (en) * 1987-08-26 1995-11-21 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US4903826A (en) * 1988-02-09 1990-02-27 EMS Medical Group Ltd., Unit 3 Dispenser for surgical guidewire
US4896767A (en) * 1988-02-09 1990-01-30 Ethicon, Inc. Suture package
US4961498A (en) * 1988-08-24 1990-10-09 Ethicon, Inc. Oval wrap suture package
US5099994A (en) * 1988-08-24 1992-03-31 Ethicon, Inc. Oval wrap suture package
US5179818A (en) * 1988-08-24 1993-01-19 Ethicon, Inc. Oval wrap suture package
US5246104A (en) * 1989-08-01 1993-09-21 United States Surgical Corporation Molded suture retainer
US5359831A (en) * 1989-08-01 1994-11-01 United States Surgical Corporation Molded suture retainer
US5236083A (en) * 1989-09-12 1993-08-17 Ethicon, Inc. One piece channel suture packages
US5165217A (en) * 1989-09-12 1992-11-24 Ethicon, Inc. One piece channel suture packages
US4967902A (en) * 1989-09-12 1990-11-06 Ethicon, Inc. One piece channel suture packages
US5056658A (en) * 1989-09-12 1991-10-15 Ethicon, Inc. One piece channel suture packages
US5024322A (en) * 1990-04-27 1991-06-18 United States Surgical Corporation Armed suture package
US5417036A (en) * 1990-08-13 1995-05-23 United States Surgical Corporation Molded suture retainer
US5131553A (en) * 1990-08-14 1992-07-21 Gordon Geasland Tubular plastic shipping, storage and dispensing container and parts usable therewith
US5052551A (en) * 1991-01-31 1991-10-01 Ethicon, Inc. Oval wrap suture package with unequal end radii
US5131533A (en) * 1991-08-28 1992-07-21 Ethicon, Inc. Needle park
US5192483A (en) * 1991-12-02 1993-03-09 W. L. Gore & Associates, Inc. Method of thermoforming a sheet around a suture needle to form a holder
US5472081A (en) * 1991-12-02 1995-12-05 W. L. Gore & Associates, Inc. Needle holder for a suture package
US5249671A (en) * 1992-02-07 1993-10-05 United States Surgical Corporation Package and method of loading for resilient surgical sutures
US5249673A (en) * 1992-02-07 1993-10-05 United States Surgical Corporation Package and method of loading for resilient surgical sutures
US5228565A (en) * 1992-02-26 1993-07-20 United States Surgical Corporation Package and method of loading for resilient surgical sutures
US5180053A (en) * 1992-02-28 1993-01-19 Ethicon, Inc. Cantilevered needle park
US5213210A (en) * 1992-02-28 1993-05-25 Ethicon, Inc. Easy-loading suture package
US5271495A (en) * 1992-04-01 1993-12-21 Ethicon, Inc. Oval wrap suture package with rotary wheel
US5263585A (en) * 1992-05-07 1993-11-23 Myriadlase, Inc. Package for an elongated flexible fiber
US5407071A (en) * 1992-05-07 1995-04-18 Myriadlase, Inc. Package for an elongated flexible fiber and method of use
US5230424A (en) * 1992-06-19 1993-07-27 Ethicon, Inc. Multi-strand suture package and cover-latching element
US5433315A (en) * 1992-12-04 1995-07-18 B. Braun Melsungen Ag Suture material pack
US5350060A (en) * 1993-01-15 1994-09-27 Ethicon, Inc. Procedure kit and package
US5284240A (en) * 1993-01-22 1994-02-08 Ethicon, Inc. No touch suture package
US5342673A (en) * 1993-02-23 1994-08-30 W. L. Gore & Associates, Inc. Sterilizable packaging material
US5503266A (en) * 1993-10-15 1996-04-02 United States Surgical Corporation Molded suture retainer with needle park
US5788062A (en) * 1994-04-04 1998-08-04 Ethicon, Inc. Suture dispenser
US5575382A (en) * 1994-12-22 1996-11-19 Ethicon, Inc. Rotary self-winding two-piece ligature package
US5655652A (en) * 1995-02-10 1997-08-12 Ethicon, Inc. Center dispense suture package
US5681740A (en) * 1995-06-05 1997-10-28 Cytotherapeutics, Inc. Apparatus and method for storage and transporation of bioartificial organs
US5675961A (en) * 1995-06-06 1997-10-14 Ethicon, Inc. Suture dispenser
US5669490A (en) * 1995-06-07 1997-09-23 United States Surgical Corporation Suture retainer
US5628395A (en) * 1995-06-23 1997-05-13 Ethicon, Inc. Suture tray package having grooved winding surface
US5704469A (en) * 1995-06-23 1998-01-06 Ethicon, Inc. Suture tray package having grooved winding surface
US5733293A (en) * 1996-05-08 1998-03-31 United States Surgical Corporation Disposable loading unit for a vascular suturing instrument
US5954748A (en) * 1996-07-15 1999-09-21 United States Surgical Corporation Gelatin coated gut suture
US6098796A (en) * 1997-06-10 2000-08-08 Ethicon, Inc. Surgical sutures dispenser and a method of coiling surgical sutures
US6135385A (en) * 1997-10-09 2000-10-24 B. Braun Surgical, S.A. Suture material dispenser
US5906273A (en) * 1997-12-05 1999-05-25 Ethicon, Inc. Armed suture package with universal dispensing capability
US5887706A (en) * 1997-12-05 1999-03-30 Ethicon, Inc. Fenestrated suture package
US6105339A (en) * 1997-12-05 2000-08-22 Ethicon, Inc. Method for making fenestrated suture packages
US6076659A (en) * 1998-01-19 2000-06-20 Ethicon, Inc. Packaging for surgical suture material
US6016905A (en) * 1998-03-06 2000-01-25 United States Surgical Corporation Surgical suture retainer package
US6138440A (en) * 1998-03-06 2000-10-31 United States Surgical Corporation Surgical suture retainer package
US5918733A (en) * 1998-04-08 1999-07-06 Ethicon, Inc. Ligating reel package
US6047815A (en) * 1998-08-31 2000-04-11 Ethicon, Inc. Package for sutures
US6464071B2 (en) * 1998-12-02 2002-10-15 Ethicon, Inc. Packaging for surgical suture
US6481569B1 (en) * 1999-03-11 2002-11-19 Ethicon, Inc. Needle park and method of use
US6481568B1 (en) * 1999-03-29 2002-11-19 Ethicon, Inc. Labyrinth package for sutures
US6135272A (en) * 1999-10-22 2000-10-24 Ethicon, Inc. Package for sutures
US6533112B2 (en) * 1999-12-03 2003-03-18 Ethicon, Gmbh Packaging for surgical suture material
US20030059463A1 (en) * 1999-12-07 2003-03-27 Mika Lahtinen Medical device
US6394269B1 (en) * 2000-09-29 2002-05-28 Ethicon, Inc. Needle package with point guards
US6644469B2 (en) * 2001-07-11 2003-11-11 Ethicon, Inc. Large needle oval wound plastic suture package
US6648133B1 (en) * 2001-07-18 2003-11-18 Biomet, Inc. Device and method for hydrating and rehydrating orthopedic graft materials
US20030198666A1 (en) * 2002-01-07 2003-10-23 Richat Abbas Oral insulin therapy
US6807737B1 (en) * 2002-05-21 2004-10-26 Christina K. Davia Ergonomic opener for intravenous bag packaging
US20050167309A1 (en) * 2002-06-04 2005-08-04 Mtf Meditech Franken Gmbh Method and device for wetting a medical implant or transplant
US20060163752A1 (en) * 2004-04-05 2006-07-27 Xingwu Wang Storage assembly
US20050278012A1 (en) * 2004-06-10 2005-12-15 Design & Performance - Cyprus Limited Protected stent delivery system and packaging
US20060029722A1 (en) * 2004-08-04 2006-02-09 Larson Marian L Apparatus for coating medical devices
US20060027467A1 (en) * 2004-08-04 2006-02-09 Ferguson Patrick J Anti-microbial suture material dispenser system
US20060193884A1 (en) * 2004-12-01 2006-08-31 Joshua Stopek Novel biomaterial drug delivery and surface modification compositions

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060091034A1 (en) * 2002-10-04 2006-05-04 Howard Scalzo Method of preparing an antimicrobial packaged medical device
US20090301033A1 (en) * 2002-10-04 2009-12-10 Ethicon, Inc. Method of preparing a packaged antimicrobial medical device
US8112973B2 (en) 2002-10-04 2012-02-14 Ethicon, Inc. Method of making a packaged antimicrobial suture
US8133437B2 (en) 2002-10-04 2012-03-13 Ethicon, Inc. Method of preparing an antimicrobial packaged medical device
US8156718B2 (en) 2002-10-04 2012-04-17 Ethicon, Inc. Method of preparing a packaged antimicrobial medical device
US8668867B2 (en) 2002-10-04 2014-03-11 Ethicon, Inc. Method of preparing an antimicrobial packaged medical device
US8960422B2 (en) 2002-10-04 2015-02-24 Ethicon, Inc. Packaged antimicrobial medical device and method of preparing same
US9149273B2 (en) 2002-10-04 2015-10-06 Ethicon, Inc. Packaged antimicrobial medical device
US9474524B2 (en) 2002-10-04 2016-10-25 Ethicon, Inc. Packaged antimicrobial medical device having improved shelf life and method of preparing same
US9597067B2 (en) 2002-10-04 2017-03-21 Ethicon, Inc. Packaged antimicrobial medical device and method of preparing same
US9597072B2 (en) 2002-10-04 2017-03-21 Ethicon, Inc. Method of preparing a packaged antimicrobial medical device
US10245025B2 (en) 2012-04-06 2019-04-02 Ethicon, Inc. Packaged antimicrobial medical device having improved shelf life and method of preparing same
US11707272B2 (en) 2012-04-06 2023-07-25 Cilag Gmbh International Packaged antimicrobial medical device having improved shelf life and method of preparing same
US11807729B2 (en) 2021-04-14 2023-11-07 Goex Corporation Polyethylene terephthalate-polyethylene naphthalate copolymer extruded sheet suitable for medical device packaging

Also Published As

Publication number Publication date
EP2079388A4 (en) 2013-03-27
US8997978B2 (en) 2015-04-07
US20080171972A1 (en) 2008-07-17
CA2662445A1 (en) 2008-04-17
AU2007307072A1 (en) 2008-04-17
EP2079388A2 (en) 2009-07-22
WO2008045338A2 (en) 2008-04-17
WO2008045338A3 (en) 2008-06-05
JP2010505520A (en) 2010-02-25
US20100116694A1 (en) 2010-05-13

Similar Documents

Publication Publication Date Title
US8997978B2 (en) Medical device package
EP1813220B1 (en) Medical device package
US8486047B2 (en) Packaged medical device
US8292068B2 (en) Medical device package
US9364215B2 (en) Medical device package
US8061520B2 (en) Medical device package including self-puncturable port
US20100096281A1 (en) Apparatus for accessing a medical package
CA2628071A1 (en) Packaged medical device

Legal Events

Date Code Title Description
AS Assignment

Owner name: TYCO HEALTHCARE GROUP LP,CONNECTICUT

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:STOPEK, JOSHUA B.;COHEN, MATTHEW D.;HOTTER, JOSEPH;AND OTHERS;SIGNING DATES FROM 20070227 TO 20070307;REEL/FRAME:023135/0168

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION