US20070016181A1 - Microwave tissue resection tool - Google Patents

Microwave tissue resection tool Download PDF

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Publication number
US20070016181A1
US20070016181A1 US11452637 US45263706A US2007016181A1 US 20070016181 A1 US20070016181 A1 US 20070016181A1 US 11452637 US11452637 US 11452637 US 45263706 A US45263706 A US 45263706A US 2007016181 A1 US2007016181 A1 US 2007016181A1
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Patent type
Prior art keywords
device
tissue
power
microwave
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11452637
Inventor
Daniel van der Weide
Fred Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Neuwave Medical Inc
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Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A61B2018/00023Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid

Abstract

A medical instrument or device is used for resonant delivery of microwave power to tissue for the purpose of resection and coagulation of vessels during surgery and/or other medical procedures. The device enables delivery of large amounts of power to tissue without the need for ground pads by accomplishing an impedance match between tissue and the characteristic impedance of the waveguide that feeds power to it. The device includes a semi-rigid coaxial cable having a center conductor which protrudes from an outer conductor by a length set to be a λ/4 (quarter-wavelength) at the frequency of excitation in the dielectric environment of the tissue of interest. The coaxial cable is shrouded by a dielectric sleeve that provides both thermal and electrical insulation. Fitted against this sleeve is a conductive sleeve whose length is set to be a λ/4 (quarter-wavelength) at the frequency of excitation in the dielectric environment of the dielectric sleeve and the shroud. The device is connected to a feed cable at its proximal end, and can be connected to a source of microwave power. A directional coupler or other wave-sampling mechanism in combination with a power sensor and feedback circuit can be used to monitor reflected power from the device during the procedure, and to control the amount of power supplied to the device.

Description

    CLAIM OF PRIORITY
  • [0001]
    This application is a Continuation-In-Part of co-pending U.S. Non-Provisional Patent Applications entitled “Triaxial Antenna for Microwave Tissue Ablation” filed Apr. 29, 2004 and assigned U.S. application Ser. No. 10/834,802; “Segmented Catheter for Tissue Ablation” filed Sep. 28, 2005 and assigned U.S. application Ser. No. 11/237,136; “Cannula Cooling and Positioning Device” filed Sep. 28, 2005 and assigned U.S. application Ser. No. 11/237,430; “Air-Core Microwave Ablation Antennas” filed Sep. 28, 2005 and assigned U.S. application Ser. No. 11/236,985; and “Microwave Surgical Device” filed May 24, 2006 and assigned U.S. application Ser. No. 11/440,331; the entire disclosures of each and all of these applications are hereby herein incorporated by reference.
  • [0002]
    This application further claims priority to U.S. Provisional Patent Applications entitled “Segmented Catheter for Tissue Ablation” filed May 10, 2005 and assigned U.S. application Ser. No. 60/679,722; “Microwave Surgical Device” filed May 24, 2005 and assigned U.S. application Ser. No. 60/684,065; “Microwave Tissue Resection Tool” filed Jun. 14, 2005 and assigned U.S. application Ser. No. 60/690,370; “Cannula Cooling and Positioning Device” filed Jul. 25, 2005 and assigned U.S. application Ser. No. 60/702,393; “Intralumenal Microwave Device” filed Aug. 12, 2005 and assigned U.S. application Ser. No. 60/707,797; “Air-Core Microwave Ablation Antennas” filed Aug. 22, 2005 and assigned U.S. application Ser. No. 60/710,276; and “Microwave Device for Vascular Ablation” filed Aug. 24, 2005 and assigned U.S. application Ser. No. 60/710,815; the entire disclosures of each and all of these applications are hereby herein incorporated by reference.
  • CROSS-REFERENCE TO RELATED APPLICATIONS
  • [0003]
    This application is related to co-pending U.S. Non-Provisional Patent Applications entitled “Triaxial Antenna for Microwave Tissue Ablation” filed Apr. 29, 2004 and assigned U.S. application Ser. No. 10/834,802; “Segmented Catheter for Tissue Ablation” filed Sep. 28, 2005 and assigned U.S. application Ser. No. 11/237,136; “Cannula Cooling and Positioning Device” filed Sep. 28, 2005 and assigned U.S. application Ser. No. 11/237,430; “Air-Core Microwave Ablation Antennas” filed Sep. 28, 2005 and assigned U.S. application Ser. No. 11/236,985; and “Microwave Surgical Device” filed May 24, 2006 and assigned U.S. application Ser. No. 11/440,331; and to U.S. Provisional Patent Applications entitled “Segmented Catheter for Tissue Ablation” filed May 10, 2005 and assigned U.S. application Ser. No. 60/679,722; “Microwave Surgical Device” filed May 24, 2005 and assigned U.S. application Ser. No. 60/684,065; “Microwave Tissue Resection Tool” filed Jun. 14, 2005 and assigned U.S. application Ser. No. 60/690,370; “Cannula Cooling and Positioning Device” filed Jul. 25, 2005 and assigned U.S. application Ser. No. 60/702,393; “Intralumenal Microwave Device” filed Aug. 12, 2005 and assigned U.S. application Ser. No. 60/707,797; “Air-Core Microwave Ablation Antennas” filed Aug. 22, 2005 and assigned U.S. application Ser. No. 60/710,276; and “Microwave Device for Vascular Ablation” filed Aug. 24, 2005 and assigned U.S. application Ser. No. 60/710,815; the entire disclosures of each and all of these applications are hereby herein incorporated by reference.
  • FIELD OF INVENTION
  • [0004]
    The present disclosure relates generally to medical instruments, and in particular to medical instruments in the field of tissue resection, coagulation, and hemostasis. Specifically, the present disclosure relates to a medical tool or device for resonant delivery of microwave power or energy to tissue for the purpose of resection and coagulation of vessels.
  • BACKGROUND
  • [0005]
    Use of energy to ablate, resect or otherwise cause necrosis in diseased tissue has proven beneficial both to human and to animal health. Electrosurgery is a well-established technique to use electrical energy at DC or radio frequencies (i.e. less than 500 kHz) to simultaneously cut tissue and to coagulate small blood vessels. Radio-frequency (RF) ablation of tumor tissue was developed from the basis of electrosurgery, and has been used with varied success to coagulate blood vessels while creating zones of necrosis sufficient to kill tumor tissue with sufficient margin.
  • [0006]
    Limitations of the above techniques center on the need for ground pads on the skin of the patient to provide a return path for the current, as well as the undesirable stimulation of the nervous system as cuts are being made; this usually requires injection of a temporary paralyzing agent. Limitations of tissue impedance, particularly as the tissue becomes desiccated or charred during the course of the procedure, limit the amount of current, and hence the amount of ablative power, that can be applied to the tissue. This in turn limits the size of vessels that can be effectively shut down.
  • [0007]
    Thus current procedures are limited when applied to resection of tumors from highly-vascularized organs, e.g. liver. Furthermore, the limitations of current and power limit the speed at which these procedures can be performed. Accordingly, there is a need for a device which overcomes the problems and disadvantages associated with current procedures, and which is an improvement thereover. The present disclosure fulfills this need.
  • SUMMARY
  • [0008]
    The present disclosure relates to delivery of microwave (e.g. approximately 800 MHz and higher frequencies) power to tissue for the purpose of ablating tissue or resecting tissue with little or no loss of blood.
  • [0009]
    The device enables delivery of large amounts of power (e.g. greater than 100 Watts) to tissue without the need for ground pads since it accomplishes an impedance match between tissue and the characteristic impedance of the waveguide that feeds power to it. This is accomplished in a hand-held format similar to many surgical tools. It can accept a variety of tips for different cutting and coagulation purposes. Furthermore, because of the impedance matching, reflected power from the tool is minimized. Reflected power can further be monitored at the generator or along the feed cable to use as feedback to the generator power control.
  • [0010]
    Numerous other advantages and features of the disclosure will become readily apparent from the following detailed description, from the claims and from the accompanying drawings in which like numerals are employed to designate like parts throughout the same.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0011]
    A fuller understanding of the foregoing may be had by reference to the accompanying drawings wherein:
  • [0012]
    FIG. 1 is a cross-sectional view of a preferred embodiment of the present disclosure, showing the arrangement of an impedance-matching sleeve and the tip.
  • [0013]
    FIG. 2 is a plan view of the preferred embodiment of the present disclosure encapsulated in a ceramic or plastic housing.
  • [0014]
    FIG. 3 is a schematic circuit diagram for a microwave power delivery and control system in accordance with the preferred embodiment of the present disclosure.
  • DESCRIPTION OF DISCLOSED EMBODIMENT(S)
  • [0015]
    While the invention is susceptible of embodiment in many different forms, there is shown in the drawings and will be described herein in detail one or more embodiments of the present disclosure. It should be understood, however, that the present disclosure is to be considered an exemplification of the principles of the invention, and the embodiment(s) illustrated is/are not intended to limit the spirit and scope of the invention and/or the claims herein.
  • [0016]
    With reference to the drawings, an example of the preferred embodiment of the energy delivery device or microwave tissue resection tool of the present disclosure is shown in FIG. 1.
  • [0017]
    As illustrated in FIG. 1, a semi-rigid coaxial cable, preferably constructed of copper or silver with a suitable low-loss dielectric, forms the basis of the device. The cable's center conductor 10 protrudes from the outer conductor 12 by a length L1, which is set to be a λ/4 (quarter-wavelength) at the frequency of excitation (e.g. 915 MHz, 2.45 GHz, or another suitable frequency) in the dielectric environment of the tissue of interest. The cable can be chosen from commercially-available standards, but it should be thick enough to be rated for the power delivered.
  • [0018]
    The coaxial cable is shrouded by a dielectric sleeve 14 that provides both thermal and electrical insulation. Fitted against this sleeve is a conductive sleeve (e.g. made of copper or silver or another suitable conductor) whose length is set to be a λ/4 (quarter-wavelength) at the frequency of excitation (e.g. 915 MHz, 2.45 GHz, or another suitable frequency) in the dielectric environment of the dielectric sleeve 14 and the shroud 30 (FIG. 2). This conductive sleeve 16 contacts the outer conductor of the coaxial cable 12 at a point 18, where it is free to slide if necessary to fine-tune the impedance matching effect. It can then be fixed in place with adhesive or other suitable mechanism.
  • [0019]
    The protrusion of the coaxial cable's center conductor 10 is shrouded by a non-stick material 20 (e.g. PTFE or Teflon) to minimize adhesion of the device to the tissue. A tip 22 at the distal end of the device can be specially formed to maximize the electric field emanating from it. For example, the tip 22 can be sharpened and optionally exposed directly to the tissue.
  • [0020]
    The device is connected to a feed cable at its proximal end 26. This cable can be optionally connectorized, by attaching any suitable connector known in the art of connecting cable, to simplify exchange of the device.
  • [0021]
    As shown in FIG. 2, the device can be enshrouded in a suitable ceramic or plastic housing 30, which can contain cooling fluid (e.g. air, nitrogen, water, etc) and microwave absorbing material (e.g. polyiron) to minimize radiation from the tool to the extent necessary or desired.
  • [0022]
    As shown in FIG. 3, the device 30 can be used in a system by which it is connected to a source of microwave power 36 via a cable 32. A directional coupler or other wave-sampling mechanism 34 in combination with a power sensor and feedback circuit 38 can be used to monitor reflected power from the device during the procedure. If the amount of reflected power exceeds a threshold, power from the generator 36 can be reduced to minimize heating of the device 30, while if the amount of reflected power is below a threshold, power can be increased to speed the procedure.
  • [0023]
    It is to be understood that the embodiment(s) herein described is/are merely illustrative of the principles of the present invention. Various modifications may be made by those skilled in the art without departing from the spirit or scope of the claims which follow.

Claims (10)

  1. 1. A device for delivery of microwave power to tissue, comprising:
    a coaxial cable;
    a resonant sleeve for impedance matching;
    a resonant tip; and
    a polymer coating for said tip.
  2. 2. The device of claim 1, further comprising a means for controlling the power delivered to the tissue based on monitoring reflected power from the device.
  3. 3. The device of claim 1, wherein the device delivers greater than 100 Watts of power to tissue without the need for ground pads.
  4. 4. A medical device comprising:
    a coaxial cable having a center conductor and an outer conductor;
    a dielectric sleeve shrouding the coaxial cable; and
    a conductive sleeve fitted against the dielectric sleeve and contacting the outer conductor;
    wherein the center conductor protrudes from the outer conductor by a length, and wherein the device accomplishes an impedance match between tissue of interest and a characteristic impedance of the waveguide that feeds power to the device.
  5. 5. The device of claim 4, wherein the conductive sleeve is positionable to adjust the impedance matching effect.
  6. 6. The device of claim 4, wherein the length that the center conductor protrudes from the outer conductor is set to be a quarter-wavelength at the frequency of excitation in the dielectric environment of the tissue.
  7. 7. The device of claim 4, wherein the conductive sleeve has a length set to be a quarter-wavelength at the frequency of excitation in the dielectric environment of the dielectric sleeve and a shroud which houses the device.
  8. 8. The device of claim 7, wherein the shroud includes cooling fluid.
  9. 9. The device of claim 7, wherein the shroud includes microwave absorbing material.
  10. 10. A method of delivering microwave power to tissue, comprising the steps of:
    feeding power to a microwave delivery device;
    accomplishing an impedance match between the tissue and a characteristic impedance of the waveguide that feeds power to the device; and
    delivering microwave power to tissue.
US11452637 2004-04-29 2006-06-14 Microwave tissue resection tool Abandoned US20070016181A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US10834802 US7101369B2 (en) 2004-04-29 2004-04-29 Triaxial antenna for microwave tissue ablation
US11237430 US20060276781A1 (en) 2004-04-29 2005-09-28 Cannula cooling and positioning device
US11237136 US7467015B2 (en) 2004-04-29 2005-09-28 Segmented catheter for tissue ablation
US11236985 US7244254B2 (en) 2004-04-29 2005-09-28 Air-core microwave ablation antennas
US11440331 US20070016180A1 (en) 2004-04-29 2006-05-24 Microwave surgical device
US11452637 US20070016181A1 (en) 2004-04-29 2006-06-14 Microwave tissue resection tool

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US11452637 US20070016181A1 (en) 2004-04-29 2006-06-14 Microwave tissue resection tool
PCT/US2006/023176 WO2006138382A3 (en) 2005-06-14 2006-06-14 Microwave tissue resection tool
PCT/US2006/028821 WO2007014208A3 (en) 2005-07-25 2006-07-25 Cannula cooling and positioning device
US11502783 US20070055224A1 (en) 2004-04-29 2006-08-11 Intralumenal microwave device
PCT/US2006/031644 WO2007022088A3 (en) 2005-08-12 2006-08-11 Intralumenal microwave device
PCT/US2006/032811 WO2007024878A1 (en) 2005-08-22 2006-08-22 Air-core microwave ablation antennas
PCT/US2006/033341 WO2007025198A3 (en) 2005-08-24 2006-08-24 Microwave device for vascular ablation
US11509123 US20070049918A1 (en) 2005-08-24 2006-08-24 Microwave device for vascular ablation
EP20060802385 EP1954207A4 (en) 2005-08-24 2006-08-24 Microwave device for vascular ablation
US13154934 US20110238061A1 (en) 2005-08-24 2011-06-07 Microwave device for vascular ablation
US13563050 US20120316551A1 (en) 2004-04-29 2012-07-31 Triaxial Antenna for Microwave Tissue Ablation
US13567881 US9031699B2 (en) 2005-09-28 2012-08-06 Kinematic predictor for articulated mechanisms
US15211161 US20170014185A1 (en) 2004-04-29 2016-07-15 Triaxial antenna for microwave tissue ablation

Related Parent Applications (5)

Application Number Title Priority Date Filing Date
US10834802 Continuation-In-Part US7101369B2 (en) 2004-04-29 2004-04-29 Triaxial antenna for microwave tissue ablation
US11237430 Continuation-In-Part US20060276781A1 (en) 2004-04-29 2005-09-28 Cannula cooling and positioning device
US11237136 Continuation-In-Part US7467015B2 (en) 2004-04-29 2005-09-28 Segmented catheter for tissue ablation
US11236985 Continuation-In-Part US7244254B2 (en) 2004-04-29 2005-09-28 Air-core microwave ablation antennas
US11440331 Continuation-In-Part US20070016180A1 (en) 2004-04-29 2006-05-24 Microwave surgical device

Related Child Applications (4)

Application Number Title Priority Date Filing Date
US10834802 Continuation-In-Part US7101369B2 (en) 2004-04-29 2004-04-29 Triaxial antenna for microwave tissue ablation
US11502783 Continuation-In-Part US20070055224A1 (en) 2004-04-29 2006-08-11 Intralumenal microwave device
US13563050 Continuation US20120316551A1 (en) 2004-04-29 2012-07-31 Triaxial Antenna for Microwave Tissue Ablation
US13567881 Continuation US9031699B2 (en) 2004-04-29 2012-08-06 Kinematic predictor for articulated mechanisms

Publications (1)

Publication Number Publication Date
US20070016181A1 true true US20070016181A1 (en) 2007-01-18

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
US11452637 Abandoned US20070016181A1 (en) 2004-04-29 2006-06-14 Microwave tissue resection tool
US13563050 Pending US20120316551A1 (en) 2004-04-29 2012-07-31 Triaxial Antenna for Microwave Tissue Ablation
US13567881 Active 2033-06-12 US9031699B2 (en) 2004-04-29 2012-08-06 Kinematic predictor for articulated mechanisms

Family Applications After (2)

Application Number Title Priority Date Filing Date
US13563050 Pending US20120316551A1 (en) 2004-04-29 2012-07-31 Triaxial Antenna for Microwave Tissue Ablation
US13567881 Active 2033-06-12 US9031699B2 (en) 2004-04-29 2012-08-06 Kinematic predictor for articulated mechanisms

Country Status (2)

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US (3) US20070016181A1 (en)
WO (1) WO2006138382A3 (en)

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US20090131926A1 (en) * 2007-11-16 2009-05-21 Tyco Healthcare Group Lp Dynamically Matched Microwave Antenna for Tissue Ablation
US20090187180A1 (en) * 2008-01-23 2009-07-23 Vivant Medical, Inc. Choked Dielectric Loaded Tip Dipole Microwave Antenna
US20090295674A1 (en) * 2008-05-29 2009-12-03 Kenlyn Bonn Slidable Choke Microwave Antenna
US20100045559A1 (en) * 2008-08-25 2010-02-25 Vivant Medical, Inc. Dual-Band Dipole Microwave Ablation Antenna
US20100045558A1 (en) * 2008-08-25 2010-02-25 Vivant Medical, Inc. Dual-Band Dipole Microwave Ablation Antenna
US20100053015A1 (en) * 2008-08-28 2010-03-04 Vivant Medical, Inc. Microwave Antenna
WO2013106036A2 (en) 2011-04-08 2013-07-18 Preston Manwaring Impedance matching circuit
US9078655B2 (en) 2009-04-17 2015-07-14 Domain Surgical, Inc. Heated balloon catheter
US9107666B2 (en) 2009-04-17 2015-08-18 Domain Surgical, Inc. Thermal resecting loop
US9131977B2 (en) 2009-04-17 2015-09-15 Domain Surgical, Inc. Layered ferromagnetic coated conductor thermal surgical tool
US9149321B2 (en) 2011-04-08 2015-10-06 Domain Surgical, Inc. System and method for cooling of a heated surgical instrument and/or surgical site and treating tissue
US9220557B2 (en) 2009-04-17 2015-12-29 Domain Surgical, Inc. Thermal surgical tool
US9265556B2 (en) 2009-04-17 2016-02-23 Domain Surgical, Inc. Thermally adjustable surgical tool, balloon catheters and sculpting of biologic materials
US9526558B2 (en) 2011-09-13 2016-12-27 Domain Surgical, Inc. Sealing and/or cutting instrument
US9549774B2 (en) 2009-04-17 2017-01-24 Domain Surgical, Inc. System and method of controlling power delivery to a surgical instrument

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EP2859862B1 (en) 2009-07-28 2017-06-14 Neuwave Medical, Inc. Ablation system
CA2800312A1 (en) 2010-05-03 2011-11-10 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9321175B2 (en) 2013-02-28 2016-04-26 Mda U.S. Systems, Llc Robotic manipulator articulation techniques
JP6104667B2 (en) * 2013-03-28 2017-03-29 株式会社日立ハイテクサイエンス Position calculating unit of the actuator, the position calculating method and a position calculating program
US9260147B2 (en) * 2013-06-26 2016-02-16 Wisconsin Alumni Research Foundation Dynamic predictor for articulated mechanisms
CN104523333B (en) * 2015-01-28 2017-03-29 南京维京九洲医疗器械研发中心 Microwave ablation therapy for obstructive thrombus one kind of an ablation antenna and manufacturing method thereof
KR101627519B1 (en) * 2015-05-04 2016-06-08 재단법인대구경북과학기술원 Robot remote control apparatus and method thereof
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