US1915945A - Rectal anesthetic - Google Patents

Rectal anesthetic Download PDF

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Publication number
US1915945A
US1915945A US599594A US59959432A US1915945A US 1915945 A US1915945 A US 1915945A US 599594 A US599594 A US 599594A US 59959432 A US59959432 A US 59959432A US 1915945 A US1915945 A US 1915945A
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US
United States
Prior art keywords
rectal
ether
anesthetic
acetylsalicylic acid
oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US599594A
Inventor
Ferdinand W Nitardy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Priority to US599594A priority Critical patent/US1915945A/en
Application granted granted Critical
Publication of US1915945A publication Critical patent/US1915945A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof

Definitions

  • This invention relates to rectal anaesthetics having an ether-oil base.
  • This invention has for its object the provision of ether-oil rectal anaesthetics characterized by accelerated activity and other valuable properties.
  • ether-oil combinations are mixed with acetylsalicylic acid.
  • the oil may be any oleaginous material-e. g., liquid petrolatum, olive oil, lanolinor an equivalent thereof, and is preferably used ,in the proportion of between onehalf and three times the volume of ether. Additional substances, preferably paraldehyde, may also be included.
  • mixtures constituted in accordance with this invention function with extraordinary rapidity, accomplishing rectal anaesthesia .in about ten minutes; and the local insensibility so induced is of exceptional quality and of gratifying safety.
  • the acetylsalicylic acid acts as a powerful analgesic on the painful mucous mem- Application filed Iarch 17, 1932. Serial No. 599, 594.
  • branes and thus, by preventing irritation, forestalls the possibility of ejection of the rectal anaesthetic.
  • a rectal anaesthetic constituted in accordance with this invention may comprise:
  • Ether- 5 fluid ounces Liquid petrolatum 2 fluid ounces Paraldehyde 2 fluid drams Acetylsalicylic acid 15 grains ture of ether, an oil, and acetylsalicylic acid.
  • a metal anaesthetic comprising a mixture of ether, liquid petrolatum, and acetylsalicylic acid.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

Patented June 27, 1933 UNITED STATES PATENT OFFICE FERDINAND W. NITARDY, OF BROOKLYN, NEW YORK, ASSIGNOR TO E. R. SQUIBB &; SONS, OI NEW YORK, N. Y., A CORPORATION OF NEW YORK RECTAL .ANESTHETIC No Drawing.
This invention relates to rectal anaesthetics having an ether-oil base.
As hitherto constituted, combinations of ether with oils, though in some respects advantageous for bringing about rectal anaesthesia, have been seriously defective in speed of action, taking about an hour to induce the required condition.
This invention has for its object the provision of ether-oil rectal anaesthetics characterized by accelerated activity and other valuable properties.
In the practice of this invention, ether-oil combinations are mixed with acetylsalicylic acid. The oil may be any oleaginous material-e. g., liquid petrolatum, olive oil, lanolinor an equivalent thereof, and is preferably used ,in the proportion of between onehalf and three times the volume of ether. Additional substances, preferably paraldehyde, may also be included.
Presumably by reason of a synergistic efl'ect exercised by the acetylsalicylic acid upon the ether, mixtures constituted in accordance with this invention function with extraordinary rapidity, accomplishing rectal anaesthesia .in about ten minutes; and the local insensibility so induced is of exceptional quality and of gratifying safety. Furthermore, the acetylsalicylic acid acts as a powerful analgesic on the painful mucous mem- Application filed Iarch 17, 1932. Serial No. 599, 594.
branes, and thus, by preventing irritation, forestalls the possibility of ejection of the rectal anaesthetic.
As an example, a rectal anaesthetic constituted in accordance with this invention may comprise:
Ether- 5 fluid ounces Liquid petrolatum 2 fluid ounces Paraldehyde 2 fluid drams Acetylsalicylic acid 15 grains ture of ether, an oil, and acetylsalicylic acid.
3. A metal anaesthetic comprising a mixture of ether, liquid petrolatum, and acetylsalicylic acid.
In witness whereof I afiix my signature. FERDINAND W. NITARDY.
US599594A 1932-03-17 1932-03-17 Rectal anesthetic Expired - Lifetime US1915945A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US599594A US1915945A (en) 1932-03-17 1932-03-17 Rectal anesthetic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US599594A US1915945A (en) 1932-03-17 1932-03-17 Rectal anesthetic

Publications (1)

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US1915945A true US1915945A (en) 1933-06-27

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2431322A (en) * 1944-05-01 1947-11-25 California Research Corp Diesel engine starting fluid
US4987127A (en) * 1989-01-31 1991-01-22 Dal Sirany Method of treating a virus outbreak

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2431322A (en) * 1944-05-01 1947-11-25 California Research Corp Diesel engine starting fluid
US4987127A (en) * 1989-01-31 1991-01-22 Dal Sirany Method of treating a virus outbreak

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