US1728965A - Apparatus for enabling the withdrawing of the contents of ampules - Google Patents

Apparatus for enabling the withdrawing of the contents of ampules Download PDF

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Publication number
US1728965A
US1728965A US75035824A US1728965A US 1728965 A US1728965 A US 1728965A US 75035824 A US75035824 A US 75035824A US 1728965 A US1728965 A US 1728965A
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Prior art keywords
syringe
ampul
coupling
contents
ampules
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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George N Hein
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NEUTYPE INSTR Co
NEUTYPE INSTRUMENT Co
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NEUTYPE INSTR Co
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Priority to US75035824 priority Critical patent/US1728965A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096Combination of a vial and a syringe for transferring or mixing their contents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06Ampoules or carpules
    • A61J1/065Rigid ampoules, e.g. glass ampoules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202Separating means
    • A61J1/2044Separating means having slits

Definitions

  • the third method is to break one end of the ampul and insert it into the end of the syringe barrel, then breaking the other end permitting the ampul contents to flow into the syringe.
  • This method like the others, has several objections in that it requires a double ended ampul, and there is always the liability of the solution flowing from the syringe outwardly through the needle during the filling operation.
  • the medi cal solutions contained in ampules are during the transfer exposed to the air, and there is a liability of particles of glass, due to the breaking of the ampul, entering the syringe during the filling operation.
  • the present invention relates to a coupling for use in connection with the filling of hypodermic syringes with the contents of ampules without unduly exposing the solution to the action of the air, and for reducing to a minimum the liability of glass entering the syringe.
  • the invention consists primarily in a coupling member of tubular formation, the opposite ends of which are adapted to receive respectively the broken end of an ampul and the needle mounting end of a syringe, said chambers being separated by a wall having a duct therein of very small diameter, insuring a means for screening or separating the glass from the solution as the same passes through the coupling. It is desirable that the wall surrounding one chamber at least be of elastic structure to receive ampules of various diameters and to tightly engage the same to preclude the entrance of air.
  • FIG. 1 is aview in side elevation of one embodiment of coupling illustrating the coupling formed in two parts, one non-elastic and the other elastic.
  • Fig. 2 is a longitudinal sectional view of the embodiment of the invention illustrated 1n Fig. 1 with an ampul received Within one end of the coupling and the syringe tip in the other end of the coupling.
  • Fig. 3 is a view in side elevation of an other form of coupling constructed of a single piece of elastic material
  • Fig. 4 is a longitudinal sectional view of the structure illustrated in Fig. 3.
  • the numeral 1 inclicates a tubular mounting member formed inwardly in one endwith a si'lbstantially conical opening 2, which termlnates at the opposite end of the member 1 in a perforation or duct 3 of relatively small diameter.
  • An annular flange 4 projects outwardly from the member 1 intermediate its ends and adjacent the same lying in spaced relation thereto the member 1 is formed with an annular bead or head 5 affording between the flange 4t and its inner surface a circumferential channel 6 for the hereinafter described purpose. 7
  • tubular elastic member one end of which is stretched as at 8 over the member 5 with its end wall received within the circumferential. channel 6.
  • the opposite end of the elastic member 7 is flared outwardly as at 9 affording an inwardly tapering channeled recess 10 into which is inserted the broken end 11 of an ampul 12 from which it is desired to withdraw the contents into a syringe, as in Fig. 1.
  • the tapered tip end 13 of asyringe barrel 14 is inserted into the conical opening 2 and the operation of the syringe pistonwill with the ampul end in serted into the end of the member 7, withdraw the medicinal solution within the am pul therefrom and into the syringe barrel.
  • the passage of the solution from the ampul into the syringe barrel is through the perforation 3 which will preclude the passage of any foreign material such as glass particles and the like into the syringe barrel.
  • the coupling is illustrated as being constructed of a single piece of elastic material 15. formed in its opposite ends with the respective substantially conical recesses 16 and 17, the recess 17 being of a diameter greater than that of the recess 16.
  • These recesses or chambers are arranged with their apexes adjacent each other, separated by the wall 18, in which is a perforation 19 of very small diameter.
  • the perforation or duct 3 in the principal embodiment and the perforation 19 in the modification are of such size as to afford filtering means for the material passing therethrough, their diameter be ing approximately that of the ordinary hypodermic needle. This diameter is suflicient to enable the filtering of particles of glass of the ampul from the fluid during its passage into the syringe, but if it is desirable afilter ing medium such as cotton or the like may be inserted into the perforation to filter finer particles from the fluid as it passes therethrough.
  • An ampul and syringe coupling comprising a structure formed with substantially conical recesses at its opposite ends, one constituting a syringe receiving socket and the other a socket for supporting an ampul in position to be emptied into the syringe, said recesses communicating at their apexes through a perforation, the wall surrounding one of said recesses being elastic.
  • An ampul and syringe coupling formed at opposite ends with aligned recesses, one affording a syringe receiving socket and the other a socket for supporting an ampul in position to be emptied into the syringe, said recesses communicating at their a-peXes through a perforation affording a means for straining the contents of the ampul.
  • An ampul and syringe coupling comprising a tubular elastic member formed in each end with a substantially conical recess, one constituting a syringe receiving socket and the other a socket for supporting an ampul in position to be emptied into the syringe, said recesses arranged with their axes in alignment and their apeXes adjacent each other, said coupling being formed with a. perforation of relatively small diameter connecting the apexes of the respective conical recesses and constituting a means for strain ing the contents of the ampul.
  • An ampul and syringe coupling provided with a syringe receiving socket and having means associated with the socket for supporting an ampul in position to be emptied into the syringe, and means carried by the coupling for straining the contents of the ampul.
  • An ampul and syringe coupling provided with a tubular end for cooperating with a syringe, and having means associated with the coupling for receiving and support ing an ampul in position to be emptied into the syringe, and means within the coupling for straining the contents of the ampul.

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Description

Sept. 24, 1929. 4 N 1,728,965
APPARATUS FOR ENABLING THE WITHDRAWING OR THE CONTENTS OF AMPULES Original Filed Nov. 17, 1924 g INVENTOR z 4W- fgyiffi ATTORN EY Patented Sept. 24, 1929 UNITED STATES PATENT OFFICE.
GEORGE N. HEIN, OF SAN FRANCISCO, CALIFORNIA, ASSIG-NOR T0 NEUTYPE IIiTSTRU- MENT COMPANY, OF SAN FRANCISCO, CALIFORNIA, A CORPORATION OF CALI- FORNIA APPARATUS FOR ENABLING THE \VITHDBAWING OF THE CONTENTS OI? AMPULES Application filed November 17, 1924, Serial No. 750,358. Renewed February 7, 1927.
Among the methods now employed for filling hypodermic syringes with medicinal solutions contained in ampules are the fol.- lowing :One method is to fracture one end of the ampul and insert through the opening afforded thereby the needle of the syringe and draw the contents of the ampul through the needle into the syringe. The objection to this method is the slowness of the operation and the difficulty of keeping the needle submerged in the liquid. An other method is to break off the end of the ampul well up onto the body and insert the end of the syringe in such opening. The objections, however, to this method are the difficulty in breaking the ampul where intended and the liability of pieces of broken glass being drawn into the syringe. The third method is to break one end of the ampul and insert it into the end of the syringe barrel, then breaking the other end permitting the ampul contents to flow into the syringe. This method, like the others, has several objections in that it requires a double ended ampul, and there is always the liability of the solution flowing from the syringe outwardly through the needle during the filling operation.
In the above mentioned methods, the medi cal solutions contained in ampules are during the transfer exposed to the air, and there is a liability of particles of glass, due to the breaking of the ampul, entering the syringe during the filling operation.
The present invention relates to a coupling for use in connection with the filling of hypodermic syringes with the contents of ampules without unduly exposing the solution to the action of the air, and for reducing to a minimum the liability of glass entering the syringe.
The invention consists primarily in a coupling member of tubular formation, the opposite ends of which are adapted to receive respectively the broken end of an ampul and the needle mounting end of a syringe, said chambers being separated by a wall having a duct therein of very small diameter, insuring a means for screening or separating the glass from the solution as the same passes through the coupling. It is desirable that the wall surrounding one chamber at least be of elastic structure to receive ampules of various diameters and to tightly engage the same to preclude the entrance of air.
With the above mentioned and other objects in View, the invention consists in the novel construction and combination of parts hereinafter described, illustrated in the accompanying drawings, and set forth in the claims hereto appended, it being understood that various changes in the form, proportion, size and minor details of construction within the scope of the claims may be resorted to without departing from the spirit or sacrificing any of the advantages of the invention.
In the drawings illustrating my invention Fig. 1 is aview in side elevation of one embodiment of coupling illustrating the coupling formed in two parts, one non-elastic and the other elastic.
Fig. 2 is a longitudinal sectional view of the embodiment of the invention illustrated 1n Fig. 1 with an ampul received Within one end of the coupling and the syringe tip in the other end of the coupling.
Fig. 3 is a view in side elevation of an other form of coupling constructed of a single piece of elastic material, and
Fig. 4: is a longitudinal sectional view of the structure illustrated in Fig. 3.
Referring to Fig. 1, the numeral 1 inclicates a tubular mounting member formed inwardly in one endwith a si'lbstantially conical opening 2, which termlnates at the opposite end of the member 1 in a perforation or duct 3 of relatively small diameter. An annular flange 4 projects outwardly from the member 1 intermediate its ends and adjacent the same lying in spaced relation thereto the member 1 is formed with an annular bead or head 5 affording between the flange 4t and its inner surface a circumferential channel 6 for the hereinafter described purpose. 7
indicates a tubular elastic member, one end of which is stretched as at 8 over the member 5 with its end wall received within the circumferential. channel 6. The opposite end of the elastic member 7 is flared outwardly as at 9 affording an inwardly tapering channeled recess 10 into which is inserted the broken end 11 of an ampul 12 from which it is desired to withdraw the contents into a syringe, as in Fig. 1. The tapered tip end 13 of asyringe barrel 14 is inserted into the conical opening 2 and the operation of the syringe pistonwill with the ampul end in serted into the end of the member 7, withdraw the medicinal solution within the am pul therefrom and into the syringe barrel. The passage of the solution from the ampul into the syringe barrel is through the perforation 3 which will preclude the passage of any foreign material such as glass particles and the like into the syringe barrel.
In Fig. 4: the coupling is illustrated as being constructed of a single piece of elastic material 15. formed in its opposite ends with the respective substantially conical recesses 16 and 17, the recess 17 being of a diameter greater than that of the recess 16. These recesses or chambers are arranged with their apexes adjacent each other, separated by the wall 18, in which is a perforation 19 of very small diameter. When in use, the tapered tip end 13 of the syringe barrel 14; is received in the recess 16 and the broken end 11 of the ampul 12 is received in the recess 17, the elasticity of the walls of the member 15 tightly gripping the surfaces of the portions 13 and 11. When in this position, the contents of the ampul are quickly and easily drawn into the syringe barrel without exposure to the atmosphere.
It is understood that these coupling members may be used repeatedly, and by their use it will be observed that the transfer of solution from ampules to syringe barrels is materially expedited over the methods now employed.
It will be observed that the perforation or duct 3 in the principal embodiment and the perforation 19 in the modification are of such size as to afford filtering means for the material passing therethrough, their diameter be ing approximately that of the ordinary hypodermic needle. This diameter is suflicient to enable the filtering of particles of glass of the ampul from the fluid during its passage into the syringe, but if it is desirable afilter ing medium such as cotton or the like may be inserted into the perforation to filter finer particles from the fluid as it passes therethrough.
I claim:
1. An ampul and syringe coupling comprising a structure formed with substantially conical recesses at its opposite ends, one constituting a syringe receiving socket and the other a socket for supporting an ampul in position to be emptied into the syringe, said recesses communicating at their apexes through a perforation, the wall surrounding one of said recesses being elastic.
2. An ampul and syringe coupling formed at opposite ends with aligned recesses, one affording a syringe receiving socket and the other a socket for supporting an ampul in position to be emptied into the syringe, said recesses communicating at their a-peXes through a perforation affording a means for straining the contents of the ampul.
8. An ampul and syringe coupling comprising a tubular elastic member formed in each end with a substantially conical recess, one constituting a syringe receiving socket and the other a socket for supporting an ampul in position to be emptied into the syringe, said recesses arranged with their axes in alignment and their apeXes adjacent each other, said coupling being formed with a. perforation of relatively small diameter connecting the apexes of the respective conical recesses and constituting a means for strain ing the contents of the ampul.
4. An ampul and syringe coupling provided with a syringe receiving socket and having means associated with the socket for supporting an ampul in position to be emptied into the syringe, and means carried by the coupling for straining the contents of the ampul. I
5. An ampul and syringe coupling provided with a tubular end for cooperating with a syringe, and having means associated with the coupling for receiving and support ing an ampul in position to be emptied into the syringe, and means within the coupling for straining the contents of the ampul.
In testimony whereof I have signed my name to this specification.
GEORGE N. HEIN.
US75035824 1924-11-17 1924-11-17 Apparatus for enabling the withdrawing of the contents of ampules Expired - Lifetime US1728965A (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2816550A (en) * 1955-11-14 1957-12-17 Milton A Lapin Dispensing cap
US2818864A (en) * 1955-11-14 1958-01-07 Adapto Inc Guide cap
US3156272A (en) * 1962-01-22 1964-11-10 William G Indrunas Bottle coupling device
US3219071A (en) * 1962-09-05 1965-11-23 Machinematics Inc Tubular sight flow device
US3261381A (en) * 1963-03-26 1966-07-19 West Chester Chem Co Two-part container for adhesives and the like
US3266533A (en) * 1964-04-10 1966-08-16 Michael J Mchale Drainage assembly
WO2004028923A1 (en) * 2002-09-24 2004-04-08 Sealants International Limited Multiple component container system
US20100016826A1 (en) * 2005-11-25 2010-01-21 Sanofi-Aventis Bushing for Receiving a Dropper Neck, and Corresponding Package and Kit
USD784556S1 (en) * 2015-05-18 2017-04-18 Adam C Alden Glass pod
WO2020254666A1 (en) * 2019-06-19 2020-12-24 Rabmed A/S Ampoule closure

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2816550A (en) * 1955-11-14 1957-12-17 Milton A Lapin Dispensing cap
US2818864A (en) * 1955-11-14 1958-01-07 Adapto Inc Guide cap
US3156272A (en) * 1962-01-22 1964-11-10 William G Indrunas Bottle coupling device
US3219071A (en) * 1962-09-05 1965-11-23 Machinematics Inc Tubular sight flow device
US3261381A (en) * 1963-03-26 1966-07-19 West Chester Chem Co Two-part container for adhesives and the like
US3266533A (en) * 1964-04-10 1966-08-16 Michael J Mchale Drainage assembly
WO2004028923A1 (en) * 2002-09-24 2004-04-08 Sealants International Limited Multiple component container system
US20100016826A1 (en) * 2005-11-25 2010-01-21 Sanofi-Aventis Bushing for Receiving a Dropper Neck, and Corresponding Package and Kit
KR101322736B1 (en) * 2005-11-25 2013-10-25 사노피 Bushing for receiving a dropper neck, and corresponding package and kit
US8800759B2 (en) 2005-11-25 2014-08-12 Sanofi-Aventis Bushing for receiving a dropper neck, and corresponding package and kit
USD784556S1 (en) * 2015-05-18 2017-04-18 Adam C Alden Glass pod
WO2020254666A1 (en) * 2019-06-19 2020-12-24 Rabmed A/S Ampoule closure

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