US11564654B2 - Method and system for calibrating an X-ray imaging system - Google Patents
Method and system for calibrating an X-ray imaging system Download PDFInfo
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- US11564654B2 US11564654B2 US16/958,894 US201816958894A US11564654B2 US 11564654 B2 US11564654 B2 US 11564654B2 US 201816958894 A US201816958894 A US 201816958894A US 11564654 B2 US11564654 B2 US 11564654B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/58—Testing, adjusting or calibrating apparatus or devices for radiation diagnosis
- A61B6/582—Calibration
- A61B6/583—Calibration using calibration phantoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/488—Diagnostic techniques involving pre-scan acquisition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3904—Markers, e.g. radio-opaque or breast lesions markers specially adapted for marking specified tissue
- A61B2090/3916—Bone tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3966—Radiopaque markers visible in an X-ray image
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3991—Markers, e.g. radio-opaque or breast lesions markers having specific anchoring means to fixate the marker to the tissue, e.g. hooks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/44—Constructional features of apparatus for radiation diagnosis
- A61B6/4429—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units
- A61B6/4435—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure
- A61B6/4441—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure the rigid structure being a C-arm or U-arm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5205—Devices using data or image processing specially adapted for radiation diagnosis involving processing of raw data to produce diagnostic data
Definitions
- the invention relates to a method and a system for determining, during operation, the geometrical features of a system for reconstructing a three-dimensional (3D) image from images acquired by an X-ray imaging system.
- the invention thus allows online calibration of an X-ray imaging system.
- the geometrical features are estimated during the rotational acquisition of a C-arm device.
- a mobile radiology system it is common to use a mobile radiology system to perform surgical or interventional procedures.
- These systems also called mobile C-arms (or block amplifier), allow the surgeon to acquire X-ray images during the intervention and to monitor the position of the tools (catheter, needle, prosthesis, etc.) that are used by the surgeon in real time in a way that is as non-invasive as possible.
- the majority of these systems make it possible to obtain two-dimensional images with a video image stream of thirty images per second. The practitioner then uses these images to mentally reconstruct the morphology of the patient in order to position the tool precisely in the area to be operated on, in real time. More recently, more sophisticated systems have emerged and make it possible to acquire a 3D image of the tool that is used by a surgeon during an intervention.
- the radiology system performs a rotation about the patient for the purpose of obtaining a set of two-dimensional 2D images. These 2D images are then processed by a reconstruction algorithm, allowing a 3D volume image to be obtained. In order to reconstruct the image, the algorithm needs to know, for each 2D image, the exact geometry of the C-arm, that is to say the position of the detector and of the X-ray source with respect to the patient.
- the systems used at present propose to calibrate the C-arm offline during preventative maintenance phases of the device, every six months or every year.
- U.S. Pat. No. 6,510,241 describes a method for calibrating a radiology apparatus, wherein a virtual volume surrounding the object to be imaged is generated and broken down into voxels (3D pixels).
- the method comprises a step of acquiring the set of numbered projected two-dimensional images and the three-dimensional image is reconstructed from the projected image.
- U.S. Pat. No. 6,320,928 describes an image reconstruction method in which a plurality of two-dimensional digital images of an object are acquired for various positions of a camera revolving around the object.
- the projected images are calibrated in a volume containing the object and divided into voxels whose spatial coordinates are identified in a chosen calibration reference frame.
- U.S. Pat. No. 6,049,582 relates to a C-arm device calibration method for a 3D reconstruction in an imaging system comprising an imaging source and an imaging plane, which uses a planar transformation to link the voxels in a voxel space and pixels in the imaging plane.
- Patent application EP3141187 relates to a calibration chart for geometrically calibrating an X-ray imaging device intended to generate three-dimensional images of an object through reconstruction based on two-dimensional projections of said object.
- the calibration chart comprises a volume support equipped with markers having a radiological absorbance that provides contrast with respect to the volume support, the markers being distributed in a three-dimensional pattern.
- the markers are distributed into subsets of markers that are distributed in respective substantially parallel straight lines such that sequences of cross-ratios are able to be constructed from the respective subsets of markers.
- Each sequence of cross-ratios comprises a single cross-ratio for each quadruplet of markers in which the markers are ordered in an order depending on the rank numbers of the respective markers along the straight line on which they are aligned, in a first predefined direction, said order being common to all of the cross-ratios, and when a subset of markers comprises at least five markers, the order of the cross-ratios in the respective sequences of cross-ratios follows a predefined rule common to all of the sequences of cross-ratios.
- a first method is based on the use of markers.
- a calibration chart is positioned on or next to a patient during the intervention. This makes it possible to precisely estimate the geometry of the device online, without having to worry about the reproducible nature of the measurement conditions.
- Patent application US 201000284601 describes such a method.
- the chart has to be produced precisely in order that the 3D position of the points is known with precision, which represents a cost
- a second type of image reconstruction method is based on using an image. These methods make use of the anatomical content of an image in order to perform both a 3D image reconstruction and a geometrical calibration.
- the invention is based on a novel approach using self-adhesive markers without having to know the 3D position of the markers.
- the invention relates to a method for calculating, during operation, the geometrical parameters of an X-ray imaging system, an object or a patient to be observed being positioned between the X-ray source and an X-ray detector detecting X-rays that have passed through the object or the patient, characterized in that it comprises at least the following steps:
- the method may comprise an offline calibration step in order to initially calculate the calibration matrices used in the final step of determining the geometry parameters.
- the initial projection matrices are calculated using the orientation sensors or the positioning sensors of the system.
- the markers may be inserted or contained in patches that are positioned on or close to the patient or the object, and the patches that are used are for example adhesive patches defined as follows:
- Another possibility consists in using small markers distributed over the entirety of a compressive garment before covering the area to be reconstructed.
- Another variant consists in using one or more anatomical markers or else in using radio-opaque markers implanted in the patient's anatomy, for example in a bone.
- the method may comprise a step of using the geometrical features of the system to reconstruct a 3D image.
- FIG. 1 shows a diagram showing a patient in position
- FIG. 2 shows an example of a patch positioned on the patient
- FIG. 3 shows a sequence of steps implemented by the method according to the invention.
- FIG. 1 illustrates an example of a device allowing a practitioner to track, in real time, the position of a tool that he is using during a surgical intervention.
- the device comprises an imaging system comprising an X-ray source 10 and an X-ray detector 11 .
- the device consists of an arch 12 or C-arm supporting the X-ray source at a first end 12 1 and the X-ray detector at a second end 12 2 .
- the arch or C-arm 12 is held on a frame 13 by a holding part 14 .
- a horizontal guide 15 attached to the frame 13 via a vertical part 16 and to the holding part 14 of the arch allows the arch to move horizontally in translation, arrow ⁇ right arrow over (H) ⁇ .
- the holding part 14 allows the C-arm 12 to perform an “orbital rotation” movement along the arrow R .
- the vertical movement is created by the horizontal translational movement of the guide and of the vertical part.
- the device also comprises a processing device 17 comprising a processor 18 configured to execute the steps of the method according to the invention, in order to determine the geometrical features of the device during the intervention by the surgeon.
- the device may comprise a screen 19 on which the surgeon is able to view the position of the tool in real time.
- the device is also equipped with orientation sensors 22 or positioning sensors 23 .
- FIG. 2 outlines one exemplary implementation of the method in which the markers are incorporated or integrated into a patch.
- the patch 30 is positioned in the upper part of the body and comprises at least one marker q.
- the coordinates of the patch or the position of the patches are not known initially. It is possible to use one or more patches to implement the method according to the invention.
- FIG. 3 illustrates an example of a sequence of steps implemented by the method according to the invention, in the case in which the markers are integrated into a patch.
- One or more patches 30 incorporating radio-opaque markers are affixed to the skin of the patient or of the object 20 , for example close to an area to be operated on, 31 . This will allow the practitioner to precisely obtain a reconstruction of the organ on which he has to operate.
- a plurality of 2D images are acquired for various viewpoints in order to perform a 3D reconstruction, 32 .
- the X-ray source and the detector are moved around the body 20 to be imaged so as to perform a plurality of projections of the body at different viewing angles. The projections that are thus performed will be used to reconstruct a three-dimensional image of the imaged body.
- the radio-opaque markers contained in the patch 30 are detected in each 2D image acquired at the X-ray detector and are paired from one image to another, 33 . Geometrical or radiometric similarity criteria are used to pair the markers.
- a 3D reconstruction of the markers is performed using a first estimation of the projection matrices, 34 .
- These projection matrices Mi may be determined during a preliminary offline calibration or predicted based on the position sensors of the system.
- These 4*3 projection matrices make it possible to match each point of the object or of the patient in the 3D space, for example with respect to the terrestrial reference frame, with its projection onto a planar 2D detector linked to the detector.
- the 3D position of the markers and the knowledge of the projection matrices are then iteratively fine-tuned, 35 .
- the geometrical parameters, specifically the projection matrices and the 3D position of the markers, are estimated jointly while minimizing the criterion set forth below.
- q ij denotes the 2D coordinates of a marker numbered j detected in an image i obtained by the system
- X is the set of L 3D points to be reconstructed
- X j is the point numbered j
- M is the set of N projection matrices
- M i is the projection matrix of the image i.
- the 3D images thus obtained may be used to allow a practitioner to precisely position his tools during an operation, 36 .
- Any other algorithm taking the coordinates of a marker as determined by executing the method at input in order to deduce the geometrical parameters of the device therefrom may be used.
- the method comprises a preliminary offline calibration step that leads to imprecise geometry of the C-arm.
- the calibration matrices resulting from the “offline” calibration are used in the fourth step in order to perform the first reconstruction.
- the markers that are used on the patch are for example spherical markers in order to facilitate detection. They may also have shapes exhibiting rotational symmetry about axes of rotational symmetry.
- the patch or patches containing the markers may be adhesively bonded directly to the patient or be positioned close to the area to be imaged.
- the self-adhesive patches may be single-use.
- the markers are for example distributed so as to cover the entire surface of the patch.
- the patch and markers assembly has for example a thickness of around 1 mm and an approximate size of 4 ⁇ 14 cm.
- the markers may be integrated into a stretchable fabric or “medical stretch suit”.
- the small markers for example opaque beads, are for example distributed over the entirety of the compressive garment before covering the assembly to be reconstructed, part of the patient for example. It is then possible to simultaneously calibrate the device, using the information obtained in the fourth step, on the one hand, and reconstruct the envelope (3D surface) of the object to be reconstructed, on the other hand. This envelope will be used a priori for the 3D reconstruction.
- the method will use one or more anatomical markers (characteristic and radio-opaque part of the human body) that correspond to points of interest present in an image.
- the markers will be extracted from the images using an image processing operation known to a person skilled in the art.
- the method will not perform step 31 of positioning a patch.
- the first step will consist in acquiring X-ray images.
- markers contained in patches and anatomical markers are associated with markers contained in patches and anatomical markers, the latter being able to be implanted in the patient's body, for example in a bone.
- the method according to the invention also makes it possible to calibrate a C-arm device using one or more markers, the position of these markers not being initially known.
Abstract
Description
-
- The chart itself may be bulky and difficult to use when the patient is present,
- The chart should have to be sterilized, since it is used in a sterile environment, and has to undergo a chemical/thermal treatment before and after it is used.
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- Using at least one marker, the marker initially having an unknown 3D position,
- Acquiring a plurality of 2D images for a plurality of viewpoints of the imaging system,
- Detecting the position of at least one marker in each of the acquired 2D images,
- Estimating the projection matrices corresponding to the projections of the object at different viewing angles and reconstructing the position of a marker in 3D from the estimation of the projection matrices.
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- An adhesive tape that will be affixed to an object or a patient,
- A set of radio-opaque markers distributed over the surface of the patch,
- A fluid-resistant outer surface.
where
qij denotes the 2D coordinates of a marker numbered j detected in an image i obtained by the system,
X is the set of
M is the set of N projection matrices, Mi is the projection matrix of the image i.
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- An adhesive tape that will be affixed to the skin of a patient or of an object, before the acquisition of the 2D images useful for reconstructing the 3D images,
- A set of radio-opaque markers distributed over the surface of the patch,
- An outer surface resistant to water, blood and friction, protecting the patch from its surroundings. The outer surface is for example made from plastic.
Claims (12)
X, M =armgin Σi=1 N Σ j=1 L ∥M iXj—qij ∥.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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FR1701389A FR3076203B1 (en) | 2017-12-28 | 2017-12-28 | METHOD AND SYSTEM FOR CALIBRATING AN X-RAY IMAGING SYSTEM |
FR1701389 | 2017-12-28 | ||
FR17/01389 | 2017-12-28 | ||
PCT/EP2018/097126 WO2019129879A1 (en) | 2017-12-28 | 2018-12-28 | Method and system for calibrating an x-ray imaging system |
Publications (2)
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US20200337670A1 US20200337670A1 (en) | 2020-10-29 |
US11564654B2 true US11564654B2 (en) | 2023-01-31 |
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US16/958,894 Active 2039-03-26 US11564654B2 (en) | 2017-12-28 | 2018-12-28 | Method and system for calibrating an X-ray imaging system |
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US (1) | US11564654B2 (en) |
EP (1) | EP3731758A1 (en) |
JP (1) | JP2021508549A (en) |
CN (1) | CN111655152A (en) |
FR (1) | FR3076203B1 (en) |
WO (1) | WO2019129879A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20210196215A1 (en) * | 2018-05-18 | 2021-07-01 | The Johns Hopkins University | Multi-motion compensation for high-quality cone-beam ct of the head |
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WO2023196184A1 (en) * | 2022-04-04 | 2023-10-12 | Intuitive Surgical Operations, Inc. | Pose-based three-dimensional structure reconstruction systems and methods |
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US6049582A (en) | 1997-12-31 | 2000-04-11 | Siemens Corporate Research, Inc. | C-arm calibration method for 3D reconstruction |
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2017
- 2017-12-28 FR FR1701389A patent/FR3076203B1/en active Active
-
2018
- 2018-12-28 CN CN201880087616.3A patent/CN111655152A/en active Pending
- 2018-12-28 US US16/958,894 patent/US11564654B2/en active Active
- 2018-12-28 JP JP2020536048A patent/JP2021508549A/en active Pending
- 2018-12-28 WO PCT/EP2018/097126 patent/WO2019129879A1/en unknown
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US20210196215A1 (en) * | 2018-05-18 | 2021-07-01 | The Johns Hopkins University | Multi-motion compensation for high-quality cone-beam ct of the head |
Also Published As
Publication number | Publication date |
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WO2019129879A1 (en) | 2019-07-04 |
JP2021508549A (en) | 2021-03-11 |
FR3076203B1 (en) | 2019-12-20 |
FR3076203A1 (en) | 2019-07-05 |
US20200337670A1 (en) | 2020-10-29 |
EP3731758A1 (en) | 2020-11-04 |
CN111655152A (en) | 2020-09-11 |
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