US1098514A - Pipette. - Google Patents

Pipette. Download PDF

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Publication number
US1098514A
US1098514A US73564912A US1912735649A US1098514A US 1098514 A US1098514 A US 1098514A US 73564912 A US73564912 A US 73564912A US 1912735649 A US1912735649 A US 1912735649A US 1098514 A US1098514 A US 1098514A
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Prior art keywords
tube
frame
pipette
fluid
rollers
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US73564912A
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Robert D Maddox
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0213Accessories for glass pipettes; Gun-type pipettes, e.g. safety devices, pumps
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids

Definitions

  • My invention relates to pipettes for taleing up, by suction, fluids in definite amounts, which are minutely accurate. It relates particularly to pipettes for use in making tests of blood, to determine the amount of corpuscles in a definite amount of the blood, and the relative proportion therein of the different kinds of corpuscles, such as red and white ones, to each other.
  • FIG. 1 is a perspective view of a pipette embodying my invention.
  • Fig, 2 is a detail view of the rollers, the frame, and the rubber tube embodying my invention.
  • Fig. is a sectional view taken upon. line 3-3 of Fig. 1.
  • the pipette embodying my invention comprises a glass tube A, into which the liquid is to be drawn by suction, a rubber tube B, the compression of which controls the pres sure of air within the glass tube, rolls D D, adapted to exert a pressure along the rub ber tube, and a frame E, in which the glass tube and the rollers are mounted.
  • the glass tube A is of the form usually used in making blood tests, that is, it has a central minute bore a, extending longitudinally through it, a bulb a, within which is a loose glass spheroid a a pointed fluidreceiving end (6 and a reduced upper end a over which the rubber tube B is fitted snugly.
  • the frame E consists of longitudinal ]S)arallel plates, between which. is held a linger piece, which has circular rings (2 6, adapted to receive the fingers of the operator, for supporting the device.
  • Rolls D D are mounted between the longitudinal plates of the frame.
  • the spindle (Z of roll D has eccentric ends (5. which extend through the plates and receive lock-nuts (Z By means of these eccentrics, the distance of spindle d from spindle d of roll D, may be regulated, according to the size of the tube
  • the periphery of roll D is knurled.
  • the frame E has upon its front end a ball 6 which is engaged by the socket g of a clamp G, which is formed from spring plates 9 7 which are held together in their centers by means of a bolt 9 and a wing nut and-at one end are curved to form a split collar 9 which fits about the tubeA, and at the other end. are swaged outward to form the socket g.
  • said amount may be drawn up into the bulb a, by removing the receiving end (L from the fluid and then rotating the roller D in a clockwise motion.
  • the roller D When one desires to eject the fluid from the pipette, he rotates the roller D in a contra-clockwise direction.
  • a pipette the combination of a frame, coniipression rollers and a fluid-receiving tube mounted on the frame, and a rubber tube connected to the fiuid-receiving tube and passing between the compression rollers whereby the rotation of the rollers compresses the tube at progressive points along its length and Varies its length between the fluid-receiving tube and the rollers.
  • a pipette comprising a frame, means on, the frame for holding a fluid-receiving tube, finger pieces upon the frame, and compression rollers mounted in the frame adjacent to the finger piece, a fluid-receiving tube mounted in the frame, and a rubber tube secured to the aforesaid tube and pass ing between the compression rollers.
  • a support adapted for use in pipettes and comprising a frame, rollers mounted upon the frame and adapted by their rotation to compress a tube between them, and means for holding the fluidreeeiving tube upon the frame.
  • a frame In combination with the fluid-receiving tubeof a pipette, a frame, an adjustable clamp mounted on the frame and adapted to engage the tube, a pair of compression rollers rotatably mounted on the frame, and a. collapsible tube secured to one end of the fluid-receiving tube and passing between the compression rollers.
  • a pipette comprising a fluid-receiving tube, a frame, a clamp, adapted to engage the tube, adjustably mounted on one end of the frame, a pair of cooperating compression rollers rotatably mounted on the frame, so that the peripheral face of one roller projects to an accessible position beyond the end of the frame opposite to the clamp, and a collapsible tube secured to the fluidreceiving tube and passing between the rollers.
  • a pipette comprising a fluid-receiving tube, a frame extending substantially at right angles to the tube, an adjustable clamp, for engaging the tube, adjustably mounted on the frame, a pair of cooperating compression rollers ro-tatably mounted on the frame, with "the peripheral edge of one roller projecting to an accessible position beyond the frame, a finger grip mounted on the frame between the rollers and the clamp, and a collapsible tube secured to one end of the fluid-receiving tube and passing between the compression rollers, whereby the rotation of the rollers compresses the tube at progressive points along its length and caries its length between the fluid-receiving tube and the rollers.
  • a pipette comprising a fluid-receiving tube, a frame, means for securing the tube to the frame, a collapsible tube secured to one end of the fluid-receiving tube, a pair of compression rollers rotatably mounted on the frame and between which the collapsible tube extends, and means for adjusting the positions of the rollers relatively to each other.

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)

Description

R. D; MADDOX.
PIPETTE.
APPLIGATION FILED DEC. 9, 1912.
' 1,098,514L Patented June 2,1914.
ROBERT D. MADIDOX, OF CINCINNATI, OHIO.
PIPE'TTE.
Specification of Letters Intent.
Patented June 2, 1914.
Application filed December 9, 1912. Serial No. 735,649.
To all whom it may concern Be it known that 1, ROBERT D. MADDOX, a citizen of the United States of America, and resident of Cincinnati, county of Hamilton, and State of Ohio, have invented certain new and useful Improvements in Pipettes, of which the following is a specification.
My invention relates to pipettes for taleing up, by suction, fluids in definite amounts, which are minutely accurate. It relates particularly to pipettes for use in making tests of blood, to determine the amount of corpuscles in a definite amount of the blood, and the relative proportion therein of the different kinds of corpuscles, such as red and white ones, to each other.
The object of my invention is a pipette, in which the suction may be accurately controlled by the hand of the operator. This object is attained by the means described in the specification, and illustrated in the accompanying drawings, in which- Figure 1 is a perspective view of a pipette embodying my invention. Fig, 2 is a detail view of the rollers, the frame, and the rubber tube embodying my invention. Fig. is a sectional view taken upon. line 3-3 of Fig. 1.
The pipette embodying my invention comprises a glass tube A, into which the liquid is to be drawn by suction, a rubber tube B, the compression of which controls the pres sure of air within the glass tube, rolls D D, adapted to exert a pressure along the rub ber tube, and a frame E, in which the glass tube and the rollers are mounted.
The glass tube A is of the form usually used in making blood tests, that is, it has a central minute bore a, extending longitudinally through it, a bulb a, within which is a loose glass spheroid a a pointed fluidreceiving end (6 and a reduced upper end a over which the rubber tube B is fitted snugly.
The frame E consists of longitudinal ]S)arallel plates, between which. is held a linger piece, which has circular rings (2 6, adapted to receive the fingers of the operator, for supporting the device. Rolls D D are mounted between the longitudinal plates of the frame. The spindle (Z of roll D has eccentric ends (5. which extend through the plates and receive lock-nuts (Z By means of these eccentrics, the distance of spindle d from spindle d of roll D, may be regulated, according to the size of the tube The periphery of roll D is knurled.
The frame E has upon its front end a ball 6 which is engaged by the socket g of a clamp G, which is formed from spring plates 9 7 which are held together in their centers by means of a bolt 9 and a wing nut and-at one end are curved to form a split collar 9 which fits about the tubeA, and at the other end. are swaged outward to form the socket g.
In operation: To adjust clamp Gr relatively to the frame E, at an angle which the operator finds most convenient, the wing out 9" is loosened, the clamp turned upon the ball g to said angle, and then held in that position by tightening the wing nut. The operator places the index linger through the ring (2, his middle finger through the ring a, which brings his thumb adj accnt to the roller D. The point of the tube A is then inserted in the fluid, which is to be drawn into the bore a of the tube A. To create suction in the tube, the operator rotatcs the roller D in a clockwise direction, by means of his thumb. This feeds the tube B upward, thereby increasing the length of the rubber tube between the glass tube A and the rollers D D and rarefying the air in the pipette, which causes the liquid to be drawn into the receiving end thereof. By imparting a very slight rotation to the roller D, a correspondingly slight movement may be imparted to the rubber tube B, and hence a minute change in the pressure of the air in the pipette may be effected. Since it requires little experience and little skill to regulate the rotation of the roller D, minute changes in the pressure of the air in the pipette can be effected, without the exercise of undue skill. 'llherefore, one may easily draw into the pipette, fluid in exact amounts. After the desired. amount of fluid has been drawn into the tube it, said amount may be drawn up into the bulb a, by removing the receiving end (L from the fluid and then rotating the roller D in a clockwise motion. When one desires to eject the fluid from the pipette, he rotates the roller D in a contra-clockwise direction.
What T claim is:
1. In a pipette, the combination of a frame, coniipression rollers and a fluid-receiving tube mounted on the frame, and a rubber tube connected to the fiuid-receiving tube and passing between the compression rollers whereby the rotation of the rollers compresses the tube at progressive points along its length and Varies its length between the fluid-receiving tube and the rollers.
2. A pipette, comprising a frame, means on, the frame for holding a fluid-receiving tube, finger pieces upon the frame, and compression rollers mounted in the frame adjacent to the finger piece, a fluid-receiving tube mounted in the frame, and a rubber tube secured to the aforesaid tube and pass ing between the compression rollers.
3. A support adapted for use in pipettes and comprising a frame, rollers mounted upon the frame and adapted by their rotation to compress a tube between them, and means for holding the fluidreeeiving tube upon the frame.
4. In combination with the fluid-receiving tubeof a pipette, a frame, an adjustable clamp mounted on the frame and adapted to engage the tube, a pair of compression rollers rotatably mounted on the frame, and a. collapsible tube secured to one end of the fluid-receiving tube and passing between the compression rollers.
A pipette comprising a fluid-receiving tube, a frame, a clamp, adapted to engage the tube, adjustably mounted on one end of the frame, a pair of cooperating compression rollers rotatably mounted on the frame, so that the peripheral face of one roller projects to an accessible position beyond the end of the frame opposite to the clamp, and a collapsible tube secured to the fluidreceiving tube and passing between the rollers.
(3. A pipette comprising a fluid-receiving tube, a frame extending substantially at right angles to the tube, an adjustable clamp, for engaging the tube, adjustably mounted on the frame, a pair of cooperating compression rollers ro-tatably mounted on the frame, with "the peripheral edge of one roller projecting to an accessible position beyond the frame, a finger grip mounted on the frame between the rollers and the clamp, and a collapsible tube secured to one end of the fluid-receiving tube and passing between the compression rollers, whereby the rotation of the rollers compresses the tube at progressive points along its length and caries its length between the fluid-receiving tube and the rollers.
7. A pipette, comprising a fluid-receiving tube, a frame, means for securing the tube to the frame, a collapsible tube secured to one end of the fluid-receiving tube, a pair of compression rollers rotatably mounted on the frame and between which the collapsible tube extends, and means for adjusting the positions of the rollers relatively to each other.
In testimony whereof, I have hereunto subscribed my name this 6th day of December, 1912.
ROBERT D. Mannox.
Witnesses:
WALTER F. 'MUBBAY, W. THORNTON Boemrr.
Copies of this patent may be obtained for five cents each, by addressing the Commissioner of Patents, Washington, D. 0."
US73564912A 1912-12-09 1912-12-09 Pipette. Expired - Lifetime US1098514A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2866340A (en) * 1955-09-06 1958-12-30 Goldberg Moshe Device for taking samples of liquid for testing
US2960868A (en) * 1957-12-23 1960-11-22 George E Price Pipette pump
US3115783A (en) * 1961-11-15 1963-12-31 Frederick E Martin Pumpette
US3327898A (en) * 1964-10-19 1967-06-27 Bioconsultants Inc Titration means and method
US4056360A (en) * 1975-02-18 1977-11-01 Risch Gerhard M Apparatus for dilution of liquid specimens
FR2429341A1 (en) * 1978-06-23 1980-01-18 Inst Biolog Fiz METERING APPARATUS AND SYSTEMS WITH PERISTALTIC ACTION
US6598765B2 (en) * 2000-06-30 2003-07-29 Brewer Science, Inc. Disposable syringe dispenser system
WO2019206944A1 (en) * 2018-04-26 2019-10-31 Robert Bosch Gmbh Device and method for preparing sample material

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2866340A (en) * 1955-09-06 1958-12-30 Goldberg Moshe Device for taking samples of liquid for testing
US2960868A (en) * 1957-12-23 1960-11-22 George E Price Pipette pump
US3115783A (en) * 1961-11-15 1963-12-31 Frederick E Martin Pumpette
US3327898A (en) * 1964-10-19 1967-06-27 Bioconsultants Inc Titration means and method
US4056360A (en) * 1975-02-18 1977-11-01 Risch Gerhard M Apparatus for dilution of liquid specimens
FR2429341A1 (en) * 1978-06-23 1980-01-18 Inst Biolog Fiz METERING APPARATUS AND SYSTEMS WITH PERISTALTIC ACTION
US6598765B2 (en) * 2000-06-30 2003-07-29 Brewer Science, Inc. Disposable syringe dispenser system
WO2019206944A1 (en) * 2018-04-26 2019-10-31 Robert Bosch Gmbh Device and method for preparing sample material
CN111989048A (en) * 2018-04-26 2020-11-24 罗伯特·博世有限公司 Apparatus and method for preparing sample material

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