US1072745A - Pharmaceutical compound. - Google Patents

Pharmaceutical compound. Download PDF

Info

Publication number
US1072745A
US1072745A US74771413A US1913747714A US1072745A US 1072745 A US1072745 A US 1072745A US 74771413 A US74771413 A US 74771413A US 1913747714 A US1913747714 A US 1913747714A US 1072745 A US1072745 A US 1072745A
Authority
US
United States
Prior art keywords
copper
per cent
lecithin
compounds
pharmaceutical compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US74771413A
Inventor
Graefin Maria Von Linden
Ernst Meissen
Near Bonn
Artur Strauss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Farbenfabriken Vorm Friedr Bayer and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farbenfabriken Vorm Friedr Bayer and Co filed Critical Farbenfabriken Vorm Friedr Bayer and Co
Priority to US74771413A priority Critical patent/US1072745A/en
Application granted granted Critical
Publication of US1072745A publication Critical patent/US1072745A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M129/00—Lubricating compositions characterised by the additive being an organic non-macromolecular compound containing oxygen
    • C10M129/02—Lubricating compositions characterised by the additive being an organic non-macromolecular compound containing oxygen having a carbon chain of less than 30 atoms
    • C10M129/26—Carboxylic acids; Salts thereof
    • C10M129/28—Carboxylic acids; Salts thereof having carboxyl groups bound to acyclic or cycloaliphatic carbon atoms
    • C10M129/38—Carboxylic acids; Salts thereof having carboxyl groups bound to acyclic or cycloaliphatic carbon atoms having 8 or more carbon atoms
    • C10M129/40—Carboxylic acids; Salts thereof having carboxyl groups bound to acyclic or cycloaliphatic carbon atoms having 8 or more carbon atoms monocarboxylic

Definitions

  • lecithin such as lecithin, jecorin, cuorin, kephalin
  • inor anic or organic copper compounds to comp ex copper comroved to be valuable remedies against in ectious diseases, especially against tuberculosis.
  • he process for producing the new compounds consists in reacting with the copper compounds upon sus nsions or solutions of lecithin or of its ana ogues, until the copper compounds used have disappeared.
  • Example 1 1 part of the dry copper salt 6 of cinnamic acid is triturated at a moderate temperature together with 2 parts of lecithin until the blue color of the copper salt has disappeared and a uniform li ht green paste is obtained, which is the comp ex com ⁇ und obtained from the cinnamate of co per and the lecithin. It is soluble with a lig t green coloration in etherand chloroform, insoluble in alcohol, and contains about 5.5 per cent. 0
  • the new complex cop er compound of lecithin being a browms -green product soluble in ether and olive oil with a light green coloration, containing about 6 per cent.

Description

' pounds which have UNITED STATES PATENT OFFICE.
eRArrN MARIA v01.- LINDEN, or BONN, ERNST "MnIssEN, or normNHoNNEr, NEAR BONN, AND AR'IUB s'rnAuss, or BARMEN, GERMANY, ASSIGNORS ro FARBEN- FABRIKEN VORM'. FBIEDR. BAYER TION OF GERMANY.
No Drawing.
Specification of Letters Patent. Application filed February 11, 1913. Serial No. 747,714.
Patented Sept. 9, 1913.
To all whom it may concern: Be it known that we, GRZFIN MARIA VON LINDEN, professorinBonn, ERNST MEISSEN, professor of medicine in Hohenhonnef, and ARTUR STRAUSS, doctor of medicine in Barmen, citizens of the German Empire, residing, respectively, in Bonn, Hohenhonnef, near Bonn, and Barmen, Germany, have invented new and useful Improvements in Pharmaceutical Compounds, of which the following is a specification.
We have found that lecithin compounds,
such as lecithin, jecorin, cuorin, kephalin can be combined with inor anic or organic copper compounds to comp ex copper comroved to be valuable remedies against in ectious diseases, especially against tuberculosis.
he process for producing the new compounds consists in reacting with the copper compounds upon sus nsions or solutions of lecithin or of its ana ogues, until the copper compounds used have disappeared.
In order to illustrate the new process more fully the following examples are given, the parts being by weight:
Example 1: 1 part of the dry copper salt 6 of cinnamic acid is triturated at a moderate temperature together with 2 parts of lecithin until the blue color of the copper salt has disappeared and a uniform li ht green paste is obtained, which is the comp ex com \und obtained from the cinnamate of co per and the lecithin. It is soluble with a lig t green coloration in etherand chloroform, insoluble in alcohol, and contains about 5.5 per cent. 0
' copper.
as an amorphous brownish-green mass, soluble in ether and olive oil*w1th a light green coloration and insoluble in alcohol. It contains about 6 per cent. of copper and 3 per cent. of phosphorus.
The product obtained from kephalin (ob,-
' tained from the brains of cows) and copper acetate is a greenish product containing 5.5-6 per cent. of co per. The complex copper compound obtained from jecorin (proneed from the liver of horse's) contains about 5.7 per cent. of copper and 2.1 per cent. of phosphorus.
We claim 1. The new complex copper compounds of lecithin compounds, which are greenish products, soluble in ether and in chloroform,- insoluble in alcohol, containing about from 5 to 6 per cent. of copper; and beingvaluable remedies against infectious dlseases, substantially as described.
2. The new complex cop er compound of lecithin, being a browms -green product soluble in ether and olive oil with a light green coloration, containing about 6 per cent.
of copper and 3 per cent. of phosphorus;
being a valuable remedy against infectious diseases, substantially as described.
In testimony whereof we havehereunto set our hands in the scribing witnesses.
GRiiFIN MARIA VON LINDEN. ERNST MEISSEN. ARTUR STRAUSS.
presence of the sub- Witnesses to signatures of Griifin Maria von Linden and Ernst Meissen:
LOUIS VANDonY, 'Bnssm F. DUNLAP. Witnesses to signature of Artur Strauss:
HELEN Norm, ALBERT NUFER.
US74771413A 1913-02-11 1913-02-11 Pharmaceutical compound. Expired - Lifetime US1072745A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US74771413A US1072745A (en) 1913-02-11 1913-02-11 Pharmaceutical compound.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74771413A US1072745A (en) 1913-02-11 1913-02-11 Pharmaceutical compound.

Publications (1)

Publication Number Publication Date
US1072745A true US1072745A (en) 1913-09-09

Family

ID=3140978

Family Applications (1)

Application Number Title Priority Date Filing Date
US74771413A Expired - Lifetime US1072745A (en) 1913-02-11 1913-02-11 Pharmaceutical compound.

Country Status (1)

Country Link
US (1) US1072745A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2465733A (en) * 1943-12-31 1949-03-29 Levis Irene Becker Lecithin-metal compound

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2465733A (en) * 1943-12-31 1949-03-29 Levis Irene Becker Lecithin-metal compound

Similar Documents

Publication Publication Date Title
US1072745A (en) Pharmaceutical compound.
EP2050754B1 (en) Method for manufacturing alkyl-methoxymethyl-trimethylsilanylmethyl amines
US1572768A (en) Pharmaceutical product
Puri et al. Derivatives of titanium with compounds having bidentate ligands: IV. Chloride acetylacetonates of titanium
US1144270A (en) Process for the production of antiseptically-acting bodies.
US2046876A (en) Preparation of diaryl dithiocarbamates
DE2301411C3 (en) Process for the preparation of Aminoäthylphosphonaten
US523018A (en) bayer
US1217447A (en) Substituted barbituric acids.
US943560A (en) Thiosalicylic compound and process of making same.
US2744912A (en) 4-o. o-diphenylphosphonylamino-antipyrin and process for its production
US1140716A (en) Diacidylpyrocatechin-ortho-carboxylic-acid compound.
US1126432A (en) Pharmaceutical product.
US675538A (en) Diethylcarbinolurethane and process of making same.
US1101734A (en) Iron salts of high molecular fatty acids containing arsenic and a halogen.
US2611784A (en) Dialkyl bicyclo [2.2.1]-5-heptene-2-phosphonates
US698694A (en) Zinc gelatose compound.
US994445A (en) Methoxymethylmenthol.
US620141A (en) Bismuth compound and process of making same
US596797A (en) Ernst ta uber
US953049A (en) Process of making 1-8-diaminonaphthalene-4-sulfonic acid.
US675539A (en) Methylisopropylcarbinolurethane and process of making same.
US1129865A (en) Oxyquinolin compounds.
US2012394A (en) Hydroxybiphenylketocarboxylic
IL38098A (en) Preparation of n-((1-ethyl-pyrrolidinyl-2)methyl)-2-methoxy-5-sulphamoylbenzamide