US1034161A - Cholesterin preparation. - Google Patents

Cholesterin preparation. Download PDF

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Publication number
US1034161A
US1034161A US62781211A US1911627812A US1034161A US 1034161 A US1034161 A US 1034161A US 62781211 A US62781211 A US 62781211A US 1911627812 A US1911627812 A US 1911627812A US 1034161 A US1034161 A US 1034161A
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United States
Prior art keywords
cholesterin
ester
preparation
oleic
germany
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US62781211A
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Max Stern
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Bayer AG
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Individual
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Publication date
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Priority to US62781211A priority Critical patent/US1034161A/en
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Publication of US1034161A publication Critical patent/US1034161A/en
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Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone

Definitions

  • I claim 1 The herein described therapeuticalcomposition comprising in intermixture esters of higher fatty acids "and esters of cholesterin, which possess a:low melting point and remain in a molten state at body temperatures and for some time even at ordinary temperatures when once melted, and which are suit-ablefor either internal assimilation or subcutaneous injection, substantially as described.
  • compositions comprising the oleic ester of cholesterin and an ester of a higher fatty acid.
  • compositions comprising the oleic' ester of cholesterin and an ester of oleic acid, substantially as described.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

' UNITED STATES PATENT OFFICE.
MAX swim, or ELBEREELD, GERMANY,
nssronou. T0 FARIBENFABRIKEN vomvr.
FRIEDR. BAYER & CO., OF ELBEBFELD, GERMANY, A CORPORATION OF GERMANY.
CHOLESTERIN PREPARATION.
No Drawing.
Specification of Letters latent. Application filed May 17, 1911. Serial No. 627,812.
Patented July 30, 1912.
they are once melted remain in the molten state at the ordinary temperature. It is thus possible 'to cause they assimilation by' the human body of cholesterin b administration either internally or by su cutaneous injection without using too-much of indifferent substances.
A mixture of 2 parts of the oleic ester of cholesterin and 1 part of the e'thylic ester of oleic acid melts at 29 C., the mixture with the methylic ester of palmitic acid melts at 31 C. 'While the pure cholesterin ester melts at 40-45 C. and is not suitable for subcutaneous injections. Olive oil or phenylpalmitate, etc., can also be used.
I claim 1. The herein described therapeuticalcomposition comprising in intermixture esters of higher fatty acids "and esters of cholesterin, which possess a:low melting point and remain in a molten state at body temperatures and for some time even at ordinary temperatures when once melted, and which are suit-ablefor either internal assimilation or subcutaneous injection, substantially as described.
2. The herein described therapeutical compositions'comprising the oleic ester of cholesterin and an ester of a higher fatty acid.
3. ,The herein described therapeutical compositions comprising the oleic' ester of cholesterin and an ester of oleic acid, substantially as described.
In testimony whereof I have hereunto set my hand in the presence of two subscribing witnesses.
CHAS. J WRIGHT, ALF ED HENKEL.
US62781211A 1911-05-17 1911-05-17 Cholesterin preparation. Expired - Lifetime US1034161A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US62781211A US1034161A (en) 1911-05-17 1911-05-17 Cholesterin preparation.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62781211A US1034161A (en) 1911-05-17 1911-05-17 Cholesterin preparation.

Publications (1)

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US1034161A true US1034161A (en) 1912-07-30

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US62781211A Expired - Lifetime US1034161A (en) 1911-05-17 1911-05-17 Cholesterin preparation.

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2498727A (en) * 1946-11-23 1950-02-28 Lanolin Plus Cosmetics Inc Isopropyl palmitate solution of lanolin cosmetic

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2498727A (en) * 1946-11-23 1950-02-28 Lanolin Plus Cosmetics Inc Isopropyl palmitate solution of lanolin cosmetic

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