Львівський Національний Університет Ветеринарної Медицини Та Біотехнологій Ім. С.З. Гжицького
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Priority to UAU201413771UpriorityCriticalpatent/UA99020U/en
Publication of UA99020UpublicationCriticalpatent/UA99020U/en
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents
(AREA)
Abstract
A method of producing a vaccine to prevention pneumococcal infections of calves comprises preparing antigen, inactivation, adjuvant introduction. Strains of Streptococcus pneumoniae are isolated from fluids and organs of sick or dead calves from local epizootic outbreak, inoculation of differential diagnostic environment is conducted, a pure culture id identified and isolated, using bioassays, epizootic strain is cultured in the broth of Hotingera, inactivating by s physical method, soaking in a water bath, hydroalcoholic propolis emulsion is added as an adjuvant, blending components. Bacterial and fungal microflora are examine to make sure that the contamination is absent pursuant to the GOST 4483 and mycoplasma pursuant to the GOST 4613, immunogenicity is determined on laboratory animals, it is packaged and sealed.
UAU201413771U2014-12-222014-12-22Method for preparing a vaccine to prevent pneumococcal disease of calves
UA99020U
(en)
Recombinant microorganisms, methods for preparing vaccine strains, antigens, and vector vaccine compositions of same, uses thereof, and related antibodies, diagnostic kit, and treatment and/or prophylactic methods
Pharmaceutical composition useful as a vaccine against Escherichia coli bacteria producing shigatoxins (stec), comprising at least one antigen or an immunogenic outer membrane protein or associated immunogenic protein and conserved in stec strains.