UA95797C2 - Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 - Google Patents

Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2

Info

Publication number
UA95797C2
UA95797C2 UAA200812109A UAA200812109A UA95797C2 UA 95797 C2 UA95797 C2 UA 95797C2 UA A200812109 A UAA200812109 A UA A200812109A UA A200812109 A UAA200812109 A UA A200812109A UA 95797 C2 UA95797 C2 UA 95797C2
Authority
UA
Ukraine
Prior art keywords
antibody
growth factor
vascular endothelial
receptor type
tumor therapy
Prior art date
Application number
UAA200812109A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Томас ФРИСС
Макс Хасманн
Вернер ШОЙЕР
Original Assignee
Ф. Хоффманн-Ля Рош Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ф. Хоффманн-Ля Рош Аг filed Critical Ф. Хоффманн-Ля Рош Аг
Publication of UA95797C2 publication Critical patent/UA95797C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Abstract

The present invention provides a method of treating a breast cancer disease in a patient who has failed prior treatment with an anti-VEGF antibody, comprising administering to the patient a therapeutically effective amount of an anti-HER2 antibody while continuing said anti-VEGF antibody therapy. The invention also provides corresponding articles of manufacture and pharmaceutical compositions.
UAA200812109A 2006-03-22 2007-03-20 Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 UA95797C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06111523 2006-03-22

Publications (1)

Publication Number Publication Date
UA95797C2 true UA95797C2 (en) 2011-09-12

Family

ID=36540182

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200812109A UA95797C2 (en) 2006-03-22 2007-03-20 Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2

Country Status (3)

Country Link
CN (1) CN101405030B (en)
UA (1) UA95797C2 (en)
ZA (1) ZA200807764B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2286330C (en) * 1997-04-07 2008-06-10 Genentech, Inc. Anti-vegf antibodies
IL143596A0 (en) * 1998-12-22 2002-04-21 Genentech Inc Vascular endothelial cell growth factor antagonists and uses thereof

Also Published As

Publication number Publication date
CN101405030A (en) 2009-04-08
ZA200807764B (en) 2009-07-29
CN101405030B (en) 2013-03-13

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