UA94428C2 - Polymorphous form and the amorphous form of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide - Google Patents

Polymorphous form and the amorphous form of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide

Info

Publication number
UA94428C2
UA94428C2 UAA200805521A UAA200805521A UA94428C2 UA 94428 C2 UA94428 C2 UA 94428C2 UA A200805521 A UAA200805521 A UA A200805521A UA A200805521 A UAA200805521 A UA A200805521A UA 94428 C2 UA94428 C2 UA 94428C2
Authority
UA
Ukraine
Prior art keywords
oxo
oxazolidine
morpholinyl
chloro
phenyl
Prior art date
Application number
UAA200805521A
Other languages
Russian (ru)
Inventor
Альфонс Груненберг
Яна Ленц
Герхард Арнольд Браун
Биргит Кайль
Кристиан Р. Томас
Original Assignee
Баер Шеринг Фарма Акциенгезельшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Баер Шеринг Фарма Акциенгезельшафт filed Critical Баер Шеринг Фарма Акциенгезельшафт
Publication of UA94428C2 publication Critical patent/UA94428C2/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

The invention relates to a novel polymorphous form and the amorphous form of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide, methods for the production thereof, medicaments containing the same, and the use thereof for fighting diseases.
UAA200805521A 2005-10-04 2006-09-22 Polymorphous form and the amorphous form of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide UA94428C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005047563A DE102005047563A1 (en) 2005-10-04 2005-10-04 New modification of specific substituted thiophene carboxamide, useful for prevention and treatment of thrombo-embolic disease, has higher solubility than known modifications

Publications (1)

Publication Number Publication Date
UA94428C2 true UA94428C2 (en) 2011-05-10

Family

ID=37852805

Family Applications (2)

Application Number Title Priority Date Filing Date
UAA201100290A UA107446C2 (en) 2005-10-04 2006-09-22 A method for polymorphic form of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide preparing in the modification ii
UAA200805521A UA94428C2 (en) 2005-10-04 2006-09-22 Polymorphous form and the amorphous form of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UAA201100290A UA107446C2 (en) 2005-10-04 2006-09-22 A method for polymorphic form of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide preparing in the modification ii

Country Status (2)

Country Link
DE (1) DE102005047563A1 (en)
UA (2) UA107446C2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009018807A1 (en) * 2007-08-06 2009-02-12 Schebo Biotech Ag Novel pharmaceuticals, method for the production thereof, and use thereof in therapy
CN102786516B (en) * 2012-08-21 2014-10-01 湖南师范大学 Method for synthesizing rivaroxaban

Also Published As

Publication number Publication date
DE102005047563A1 (en) 2007-04-05
UA107446C2 (en) 2015-01-12

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