UA92740C2 - N-sulphonylpyrroles and their use as histone deacetylase inhibitors - Google Patents

N-sulphonylpyrroles and their use as histone deacetylase inhibitors

Info

Publication number
UA92740C2
UA92740C2 UAA200711109A UAA200711109A UA92740C2 UA 92740 C2 UA92740 C2 UA 92740C2 UA A200711109 A UAA200711109 A UA A200711109A UA A200711109 A UAA200711109 A UA A200711109A UA 92740 C2 UA92740 C2 UA 92740C2
Authority
UA
Ukraine
Prior art keywords
sulphonylpyrroles
histone deacetylase
deacetylase inhibitors
inhibitors
compounds
Prior art date
Application number
UAA200711109A
Other languages
Russian (ru)
Inventor
Томас Майер
Томас Бер
Томас Беккерс
Астрид Циммерманн
Зигфрид Шнайдер
Фолькер Гекелер
Original Assignee
4Сц Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 4Сц Аг filed Critical 4Сц Аг
Publication of UA92740C2 publication Critical patent/UA92740C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.(I)
UAA200711109A 2005-03-15 2006-03-14 N-sulphonylpyrroles and their use as histone deacetylase inhibitors UA92740C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05102019 2005-03-15

Publications (1)

Publication Number Publication Date
UA92740C2 true UA92740C2 (en) 2010-12-10

Family

ID=34938979

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200711109A UA92740C2 (en) 2005-03-15 2006-03-14 N-sulphonylpyrroles and their use as histone deacetylase inhibitors

Country Status (2)

Country Link
UA (1) UA92740C2 (en)
ZA (1) ZA200706012B (en)

Also Published As

Publication number Publication date
ZA200706012B (en) 2008-09-25

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