UA92450C2 - 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia - Google Patents

1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia

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Publication number
UA92450C2
UA92450C2 UAA200508000A UA2005008000A UA92450C2 UA 92450 C2 UA92450 C2 UA 92450C2 UA A200508000 A UAA200508000 A UA A200508000A UA 2005008000 A UA2005008000 A UA 2005008000A UA 92450 C2 UA92450 C2 UA 92450C2
Authority
UA
Ukraine
Prior art keywords
prophylaxis
modulators
diabetes
metabolism
treatment
Prior art date
Application number
UAA200508000A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Роберт М. Джоунз
Греем Семпл
Беатриц Фьораванти
Гильерми Перейра
Имельда Кальдерон
Джейн Ю
Камешвари Дуввури
Цзинь Сунь Керолайн Чои
Ифен Сюн
Вибха Дейв
Михай Д. Азимиора
Original Assignee
Арена Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Арена Фармасьютикалз, Инк. filed Critical Арена Фармасьютикалз, Инк.
Publication of UA92450C2 publication Critical patent/UA92450C2/en

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to certain 1,2,3-trisubstituted aryl and heteroaryl derivatives of Formula (Ia) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.
UAA200508000A 2003-01-14 2004-01-14 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia UA92450C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44039403P 2003-01-14 2003-01-14

Publications (1)

Publication Number Publication Date
UA92450C2 true UA92450C2 (en) 2010-11-10

Family

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Family Applications (1)

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UAA200508000A UA92450C2 (en) 2003-01-14 2004-01-14 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia

Country Status (3)

Country Link
CN (1) CN1835943B (en)
UA (1) UA92450C2 (en)
ZA (1) ZA200505001B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8513233B2 (en) * 2007-10-11 2013-08-20 Shanghai Institute Of Materia Medica, Cas Pyrimidinyl-propionic acid derivatives and their use as PPAR agonists
AU2010261341B2 (en) * 2009-06-18 2014-02-06 Cadila Healthcare Limited Novel GPR 119 agonists
PL2473049T3 (en) * 2009-09-04 2019-07-31 Biogen Ma Inc. Bruton's tyrosine kinase inhibitors
FR2976942B1 (en) * 2011-06-23 2013-07-12 Metabolys PIPERAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF IN THE TREATMENT OF INSULIN RESISTANCE
US11174243B2 (en) 2016-07-21 2021-11-16 Sunesis Pharmaceuticals, Inc. Succinate forms and compositions of Bruton's tyrosine kinase inhibitors
CN113518776B (en) * 2019-04-30 2024-03-26 四川科伦博泰生物医药股份有限公司 Benzothiophene compound and preparation method and application thereof
CN115340526B (en) * 2021-05-12 2024-02-02 中国科学院上海药物研究所 Phthalimide compound, pharmaceutical composition, preparation method and application thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0556889A1 (en) * 1992-02-18 1993-08-25 Duphar International Research B.V Method of preparing aryl(homo)piperazines
GB9400889D0 (en) * 1994-01-18 1994-03-16 Sandoz Ltd Novel compounds
WO1996033994A1 (en) * 1995-04-28 1996-10-31 Nippon Soda Co., Ltd. Amino-substituted derivatives, process for the preparation thereof, and herbicide
WO1996036613A1 (en) * 1995-05-19 1996-11-21 Nippon Soda Co., Ltd. Substituted benzoic acid derivatives, process for the production thereof, and herbicides
US6187777B1 (en) * 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
KR100521735B1 (en) * 2000-02-25 2005-10-17 에프. 호프만-라 로슈 아게 Adenosine receptor modulators
CN1245391C (en) * 2001-06-01 2006-03-15 弗·哈夫曼-拉罗切有限公司 Pyrimidine, Triazine and pyrazine derivatives as glutamate receptors
JP4510442B2 (en) * 2001-06-26 2010-07-21 ブリストル−マイヤーズ スクイブ カンパニー N-heterocyclic inhibitor of TNF-α expression

Also Published As

Publication number Publication date
ZA200505001B (en) 2007-02-28
CN1835943A (en) 2006-09-20
CN1835943B (en) 2012-03-07

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