UA89200C2 - S-TRIAZOLYL-α-MERCAPTOACETANILDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE - Google Patents
S-TRIAZOLYL-α-MERCAPTOACETANILDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASEInfo
- Publication number
- UA89200C2 UA89200C2 UAA200702491A UAA200702491A UA89200C2 UA 89200 C2 UA89200 C2 UA 89200C2 UA A200702491 A UAA200702491 A UA A200702491A UA A200702491 A UAA200702491 A UA A200702491A UA 89200 C2 UA89200 C2 UA 89200C2
- Authority
- UA
- Ukraine
- Prior art keywords
- triazolyl
- reverse transcriptase
- mercaptoacetanildes
- inhibitors
- hiv reverse
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
Abstract
A series of S-triazolyl α-mercaptoacetanilides having general structure (1) are provided, where Q is COH, CONR, SOH, or SONR. The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60421904P | 2004-08-25 | 2004-08-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
UA89200C2 true UA89200C2 (en) | 2010-01-11 |
Family
ID=40908676
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200702491A UA89200C2 (en) | 2004-08-25 | 2005-08-25 | S-TRIAZOLYL-α-MERCAPTOACETANILDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE |
UAA200909742A UA97139C2 (en) | 2004-08-25 | 2005-08-25 | Normal;heading 1;heading 2;heading 3;2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID AND METHYL ESTER |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200909742A UA97139C2 (en) | 2004-08-25 | 2005-08-25 | Normal;heading 1;heading 2;heading 3;2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID AND METHYL ESTER |
Country Status (3)
Country | Link |
---|---|
KR (1) | KR100940058B1 (en) |
UA (2) | UA89200C2 (en) |
ZA (1) | ZA200702390B (en) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7642277B2 (en) * | 2002-12-04 | 2010-01-05 | Boehringer Ingelheim International Gmbh | Non-nucleoside reverse transcriptase inhibitors |
-
2005
- 2005-08-25 UA UAA200702491A patent/UA89200C2/en unknown
- 2005-08-25 KR KR1020097020694A patent/KR100940058B1/en active IP Right Grant
- 2005-08-25 UA UAA200909742A patent/UA97139C2/en unknown
-
2007
- 2007-03-22 ZA ZA200702390A patent/ZA200702390B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200702390B (en) | 2008-10-29 |
KR100940058B1 (en) | 2010-02-04 |
KR20090111357A (en) | 2009-10-26 |
UA97139C2 (en) | 2012-01-10 |
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