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Application filed by Ніколай Борісовіч СорокінfiledCriticalНіколай Борісовіч Сорокін
Priority to UAU201310083UpriorityCriticalpatent/UA88225U/en
Publication of UA88225UpublicationCriticalpatent/UA88225U/en
The method for manufacturing the pharmaceutical product comprises the dissolution of Nalbuphine hydrochloride in the water for injections followed by nitrogen bubbling. Then sodium citrate, citric acid, sodium hydrochloride and/or sodium metabisulfite or sodium metabisulfate are added with optional pH adjustment to 3.4-3.7 with 0.1 M solution of hydrochloric acid and nitrogen bubbling. The solution is sterilized by filtration and dispensed into ampoules/bottles. The dosage units are finally packaged.
UAU201310083U2013-08-132013-08-13Method for manufacturing nalbuphine-containing pharmaceutical product
UA88225U
(en)