UA76096C2 - 3-(4,5-dihydroisoxazole -5-yl)benzoylpyrazole and use thereof as herbicide - Google Patents

Abstract

The invention relates to 3-(4,5-dihydroisoxazole-5-yl)benzoylpyrazole of the formula (I), wherein the variables have the following meanings: R1, R2 represent halogen, alkyl, alkoxy, alkylsulfonyl; R3 - R6 represent hydrogen; R7 represents alkyl, halogenalkyl, dialkoxymethyl; R11 represents optionally substituted pyrazole that is bound in the 4 position. The invention also relates to the agriculturally useful salts thereof, to methods and to intermediate products for preparing the 3-(4,5-dihydroisoxazole-5-yl)benzoylpyrazole, to agents containing them and to the use of said derivatives or the agents containing them for combating undesired plants. (I)

Description

Description of the invention

This invention relates to 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles of formula 5. on, t g -Ж is

Horses and Owls. "AND. M is I NECK Me and he r dn r yh 70 I. I che V Щ ! back in Sh-

And where the substitutes have the following meanings:

B", B? mean hydrogen, nitro, shalogen, cyano, C.-Svalkyl, C.-Svhaloalkyl, C.-Svalkoxy,

S.-Swhaloalkyloxy, S.--Swalkylthio, S.--Swhaloalkylthio, S.--Swalkylsulfinyl, S.--Swhaloalkyl-sulfinyl,

C.-Svalkylsulfonyl or C.-Svhaloalkylsulfonyl;

EZ means hydrogen, halogen or S.-Svalkyl; 27 hydrogen or S. Salkil; 25, 85 hydrogen, halogen, cyano, nitro, Ci-C; alkyl, Ci-C, alkoxy-C. , di-(C4-C.alkyl)-amino-C.-Alkyl, di-(C.--C;alkyl)amino-imino-C.-Alkyl, hydroxyimino-C.-Alkyl,

C.-C.-Alkoxyimino-C.i.-C.alkyl, C.-C., Alkoxycarbonyl-C.-C.alkyl. , school

C.-C.cyanoalkyl, C.sub.3-C.sub.cycloalkyl, C.sub.1-C.sub.6,-Alkoxy, C.-S.-Salkoxy-C.sub.6-C.sub.Alkoxy, C.sub.-C.sub.haloalkyl,

C.i.-C.-alkylthio, C.-C.-haloalkylthio, di-(C.-C.-alkyl)-amino, soc, phenyl or benzyl, and both of the latter substituents may be partially or fully halogenated and/ or may have from one to three of the following groups: nitro, cyano, C1-Sulfalkyl, C1-C1haloalkyl, C1-C1. or c zo B i 25 together form a Co-Svalcandiyl chain, which can be substituted one to four times

C.-C.alkyl and/or may be interrupted by oxygen or optionally replaced by C.-C.alkyl with nitrogen; me)

B means halogen, cyano, hydroxy, C.--Swalkyl, C.--Swhaloalkyl, C.--Swallowoxy, C.-4-Swhaloalkyl, Ha»)

C.-Cu-alkylthio, C.-Cvhalogenalkylthio, C.--Cvalkylsulfinyl, C.-Cvhalogenalkylsulfinyl, C.--Cvalkylsulfonyl, so

C.i-Ci-haloalkylsulfonyl, amino, C.--Cialkylamino, di-(C.i-Ci-alkyl)damino, di-(Ci-Ci-alkyl)methyl, hydroxyimino-Ci-Cialkyl, Ci-Ci-Ci-alkyl -C4-Slalkil or SOKU; and -

BZ stands for hydrogen, C.-Slalkyl, C.i-Sahaloalkyl, hydroxy, C.--Slalkoxy, C.4-Slalkoxy-Co-C;alkoxy,

C.-C.halogenalkoxy, C3-Svalkenyloxy, C3-Svalkynyloxy or MAV o;

IN? hydrogen or S.-Salkil; « 20 VO S.-Sualkil; -в с В" means the pyrazole of the formula ІІ 14 bound in position 4. В "» M -

CPC

"Mk CHE (e)) dz I

TE sh12 o y, e

Ge) as | | | Also in means hydrogen, C.i-C;alkyl, C.i-Ci-haloalkyl, C3-C6-alkenyl, C3-C;alkynyl, C.4-C;alkylcarbonyl, c» cC.-C,-haloalkylcarbonyl, C .-C.alkylsulfonyl, C.-C., -haloalkylsulfonyl, thienylmethyl, phenyl, benzyl, phenylcarbonyl, phenylsulfonyl or phenylcarbonylmethyl, and the phenyl residue of the last five substituents may be partially or fully halogenated and/or may have from one to three of the following groups: nitro, cyano, 25 C.-Sualkyl, C.-C.haloalkyl, C.-C.-alkoxy or C.-C.haloalkyl;

HF) BZ means C1-Salkyl, C1-C8haloalkyl or C3-C8-cycloalkyl; g B" means hydrogen, C-C alkyl or C 3-C cycloalkyl; as well as their agriculturally applicable salts. In addition, the invention relates to a method and intermediate products for obtaining compounds of formula I, means containing these compounds, as well as the use of these derivatives or agents containing them to control unwanted plants.

From literary sources, for example, from UMO 96/26206, pyrazol-4-yl-benzoyl derivatives are known.

The herbicidal properties of the compounds known so far, as well as their tolerance by cultivated plants, however, are satisfactory only conditionally. Therefore, the purpose of this invention is to develop new, herbicidally active compounds with improved properties.

According to this, 3-(4,5-dihydroisoxazol-5-yl)/benzoylpyrazoles of formula !, as well as their herbicidal activity, were developed.

Next, herbicides containing compounds of formula I were developed! and have a very good herbicidal effect.

In addition, a method of combating unwanted plant growth using compounds of formula I was developed.

Compounds of formula I may contain, depending on the type of substitution, one or more centers of chirality and then may have the form of pure enantiomers or diastereomers. The object of the invention is both pure enantiomers or diastereomers, and their mixtures.

Compounds of formula I can be presented in the form of their salts used in agriculture, and the type of salt, as a rule, does not matter. In general, salts of such cations, respectively, acid-addition salts of such acids, cations, respectively, whose anions do not have a negative effect on the herbicidal effect of compounds I, are used.

In the function of cations, in particular, ions of alkali metals, preferably such as lithium, sodium or potassium, alkaline earth metals, preferably calcium or magnesium, and transition metals, preferably manganese, copper, zinc and iron, as well as ammonium, and here from one to four hydrogen atoms can be replaced by C.-C.alkyl, hydroxy-C.i.-C.alkyl, and/or phenyl or benzyl, preferably ammonium, diisopropylammonium, tetramethylammonium, tetrabutylammonium. trimethylbenzylammonium, then phosphonium ions, sulfonium, preferably tri(C.-C,-alkyl)usulfonium and sulfoxonium ions, preferably tri(C.-C,-alkyl)usulfoxonium.

The anions of the acid additive salts used are primarily chloride, bromide, fluoride, hydrogen sulfate, sulfate, dihydrogen phosphate, hydrogen phosphate, nitrate, hydrogen carbonate, carbonate, hexafluorosilicate, hexafluorophosphate, benzoate, as well as anions of C. and C. alkanoic acids, preferably formate , acetate, propionate and butyrate.

Given for substitutes KE 1-7? or as residues on phenyl rings, organic parts of the molecule are collective concepts for individual enumeration of individual links of groups. All hydrocarbon chains, namely, alkyl, haloalkyl, cyanoalkyl, alkenyl, alkynyl, alkoxy, haloalkyl, alkylthio, Ha g; галогеналкілтіо, алкільсульфінільні, галогеналкілсульфінільні, алкілсульфонільні, галогеналкілсульфонільні, алкілкарбонільні, галогеналкілкарбонільні, алкоксикарбонільні, галогеналкоксикарбанільні, алкенілокси, о алкінілокси, алкіламіно, діалкіламіно, алкоксіалкільні, діалкоксиметильні, алкілтісалкільні, діалкіламінсалкільні, діалкіламіноімінсалкільні, гідроксіїміноалкільні, алкоксіїмінсалкільні, алкоксикарбонілалкільні та алкоксіалкокси-ч-астини можуть бути branched or unbranched. Unless otherwise specified, halogenated substituents preferably carry from one to five identical or different halogen atoms. Halogen means fluorine, chlorine, bromine or iodine. b

Then there are the following meanings for substitutes: aw! - C.-Slalkyl, as well as alkyl parts of C.-C.alkylcarbonyl, di-(C4-C.-alkyl)-C.4-C-alkyl di-(C4-C.-alkyl)-aminoimino-C. 4-C,-alkyl, C4-C-alkoxyimino-C.4-C,-alkyl and hydroxyimino-C.-C.alkyl mean, for example, methyl, ethyl, propyl, 1-methylethyl, butyl, 1 -methylpropyl, 2-methylpropyl and 1,1-dimethylethyl; - - C4-C6-alkyl means C-C-alkyl, given above, as well as, for example, pentyl, 1-methylbutyl, 2-methylbutyl,

3-methylbutyl, 2,2-dimethyl-propyl, 1-ethylpropyl, hexyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1- dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, « 2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1 -ethyl-1-methyl-propyl and 1-ethyl-3-methylpropyl; - с - Сб.-C,-haloalkyl, as well as the haloalkyl parts of C.-C.haloalkylcarbonyl also mean the C.-C,-alkyl residue, given above, partially or completely substituted by fluorine, chlorine, bromine and/or iodine , for example, chloromethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoromethyl, dichlorofluoromethyl, chlorodifluoromethyl, bromomethyl, iodomethyl, 1-fluoroethyl, 1-chloroethyl, 1-bromomethyl, 1-iodoethyl, 2-fluoroethyl, 2- chloroethyl, 2-bromomethyl, 2-iodoethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, -I 2-chloro-2-fluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro- 2-fluoroethyl, 2,2,2-trichloroethyl, pentafluoroethyl, 2-fluoropropyl, 3-fluoropropyl, 2,2-difluoropropyl, 2,3-difluoropropyl, 2-chloropropyl, 3-chloropropyl, 2,3-dichloropropyl, b 2 -bromopropyl, 3-bromopropyl, 3,3,3-trifluoropropyl, 3,3,3-trichloropropyl, 2,2,3,3,3-pentafluoropropyl, av!heptafluoropropyl, 1-(fluoromethyl)-2-fluoroethyl, 1 --(chloromethyl)-2-chloroethyl, 1-"(bromomethyl)-2-bromomethyl, 4-fluorobutyl, 4-chlorobutyl, 4-bromobutyl and nanofluorobutyl; o - C.-Ce-haloalkyl means in reduced C.-C.haloalkyl, as well as, for example, 5-fluoropentyl,

FO B-chloropentyl, 5-bromopentyl, 5-iodopentyl, undecafluoropentyl, b-fluorohexyl, b-chlorohexyl, b-bromohexyl, b-iodohexyl and dodecafluorohexyl; - C.-C.cyanoalkyl means, for example, cyanomethyl, 1-cyanoeth-1-yl, 2-cyanoeth-1-yl, 1-cyanoprop-1-yl, 2-cyanoprop-1-yl, 3-cyanoprop-1 -yl, 1-cyanoprop-2-yl, 2-cyanoprop-2-yl, 1-cyanobut-1-yl, 2-cyanobut-1-yl,

3-cyanobut-1-yl, 4-cyanobut-1-yl, 1-cyanobut-2-yl, /2-cyanobut-2-yl, 1-cyanobut-3-yl, /2-cyanobut-3-yl,

F, 1-cyano-2-methyl-prop-3-yl, 2-cyano-2-methyl-prop-3-yl, 3-cyano-2-methyl-prop-3-yl and 2-cyanomethyl-prop- 2-il; co - C3-C.alkenyl means, for example, prop-1-en-1-yl, prop-2-en-1-yl, 1-methyl-ethen-1-yl, buten-1-yl, buten-2 -yl, buten-3-yl, 1-methyl-prop-1-en-1-yl, 2-methyl-prop-1-en-1-yl, 1-methyl-prop-2-en-1-yl or bo 2-methyl-prop-2-en-1-yl; - C3-Sualquinyl means, for example, prop-1-yn-1-yl, prop-2-yn-1-yl, but-1-yn-1-yl, but-1-yn-3-yl, but- 1-yn-4-yl or but-2-yn-1-yl; - C.-C.Alkoxy, as well as the alkoxy-parts of di-(C.1-C,-Alkoxy)methyl and di-(C.4-C,-Alkoxy)-C.--C,-Alkyl, mean , for example, methoxy, ethoxy, propoxy, 1-methylethoxy, butoxy, 1-methylpropoxy, 2-methylpropoxy and 65 1,1-dimethyl-ethoxy; - C.-Salkoxy, as well as C.4-Cv-Alkoxyimino-C--C.l.alkyl means the above

C.-C.-Alkoxy, as well as, for example, pentoxy, 1-methylbutoxy, 2-methylbutoxy, 3-methoxybutoxy, 1,1-dimethylpropoxy, 1,2-dimethylpropoxy, 2,2-dimethylpropoxy, 1-ethylpropoxy, hexoxy , 1-methylpentoxy, 2-methylpentoxy, 3-methylpentoxy, 4-methylpentoxy, 1,1-dimethylbutoxy, 1,2-dimethylbutoxy, 1,3-dimethylbutoxy, 2,2-dimethylbutoxy, 2,3-dimethylbutoxy, 3,3 -dimethylbutoxy, 1-ethylbutoxy, 2-ethylbutoxy, 1,1,2-trimethylpropoxy, 1,2,2-trimethylpropoxy, 1-ethyl-1-methylpropoxy and 1-ethyl-2-methylpropoxy; - C.-C.-halo-alkoxy means the above-mentioned C.-C.-alkyl-residue substituted partially or completely by fluorine, chlorine, bromine and/or iodine, namely, for example, fluoromethoxy, difluoromethoxy, trifluoromethoxy, 7/0 chlorodifluoromethoxy, bromodifluoromethoxy, 2-fluoroethoxy, 2-chloroethoxy, 2-bromo-methoxy, 2-iodoethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-2-fluoro-ethoxy, 2-chloro-2, 2-difluoroethoxy, 2,2-dichloro-2-fluoroethoxy, 2,2,2-trichloro-ethoxy, pentafluoroethoxy, 2-fluoropropoxy, 3-fluoropropoxy, 2-chloropropoxy, 3-chloropropoxy, 2-bromopropoxy, 3-bromopropoxy, 2,2-difluoropropoxy, 2,3-difluoropropoxy, 2,3-dichloropropoxy, 3,3,3-trifluoropropoxy, 3,3,3-trichloropropoxy, 2,2,3,3,3-pentafluoropropoxy, 7/5 Heptafluoropropoxy , 1-(fluoromethyl)-2-fluoroethoxy, 1-(chloromethyl)-2-chloroethoxy, 1-«(bromomethyl)-2-bromomethoxy, 4-fluorobutoxy, 4-chlorobutoxy, 4-bromobutoxy and nonafluorobutoxy, - C.-Co -haloalkyl means the above C.-C.haloalkyl, as well as, for example, 5-fluoropentoxy,

b-chloropentoxy, 5-bromopentoxy, 5-iodopentoxy, undecafluoropentoxy, b-fluorohexoxy, b-chlorohexoxy, b-bromohexoxy, b-iodohexoxy and dodecafluorohexoxy, - Sb.-C,-alkylthio means, for example, methylthio, ethylthio, propylthio, 1-methyl-ethylthio, butylthio, 1-methylpropylthio, 2-methylpropylthio | 1,1-dimethyl-ethylthio, - C1-C1-alkylthio means the above C1-C1-alkylthio, as well as, for example, pentylthio, 1-methylbutylthio, 2-methylbutylthio, 3-methylbutylthio, 2,2-dimethylpropylthio, 1-ethylpropylthio, hexylthio, 1,1-dimethylpropylthio, 1,2-dimethylpropylthio, 1-methylpentylthio, 2-methylpentylthio, 3-methylpentylthio, 4-methylpentylthio, 1,1-dimethylbutylthio, 1,2-dimethylbutylthio, 1,3 -dimethylbutylthio 2,2-dimethylbutylthio, 2,3-dimethylbutylthio, 3,3-dimethylbutylthio, 1-ethylbutylthio, 2-ethylbutylthio, 1,1,2-trimethylpropylthio, /1,2,2-trimethylpropylthio, (8) 1- ethyl-1-methylpropylthio and 1-ethyl-2-methylpropylthio, - C,-C,-haloalkylthio means the above-mentioned C,-C,-alkylthio residue partially or completely substituted by fluorine, chlorine, bromine and/or iodine, namely , for example, fluoromethylthio, difluoromethylthio, trifluoromethylthio, Hezo Xchlorodifluoromethylthio, bromodifluoromethylthio, 2-fluoroethylthio, 2-chloroethylthio, 2-bromomethylthio, 2-iodoethylthio, 2,2-difluoroethylthio, 2,2,2-trifluoroethylthio, 2 ,2,2-trichloroethylthio, 2-chloro-2-fluoro-ethylthio, Me) 2-chloro p-2,2-difluoroethylthio, 2,2-dichloro-2-fluoroethylthio, pentafluoroethylthio, 2-fluoropropylthio, 3-fluoropropylthio, "3 2-chloropropylthio, 3-chloropropylthio, 2-bromopropylthio, 3-bromopropylthio, 2,2- difluoropropylthio, 2,3-difluoropropylthio, 2,3-dichloropropylthio, 3,3,3-trifluoropropylthio, 3,3,3-trichloropropylthio, 2,2,3,3,3-pentafluoropropylthio, re) heptafluoropropylthio, 1-(fluoromethyl) )-2-fluoroethylthio, 1-(chloromethyl)-2-chloroethylthio, 1-"bromomethyl)-2-bromomethylthio, n-4-fluorobutylthio, 4-chlorobutyl-thio, 4-bromobutylthio and nonafluorobutylthio; - C.-Ce-haloalkylthio means the above C.-C.haloalkylthio, as well as, for example, 5-fluoropentylthio,

B-chloropentylthio, 5-bromopentylthio, 5-iodopentylthio, undecafluoropentylthio, b-fluorohexylthio, b-chlorohexylthio, b-bromohexylthio, b-iodohexylthio and dodecafluorohexylthio; " - С1-Св-alkylsulfinyl means (С--Св-alkyl-5(-0О)-) for example, methylsulfinyl, ethylsulfinyl, stv) c propylsulfinyl, 1-methylethylsulfinyl, butylsulfinyl, 1-methylpropylsulfinyl, 2-methylpropylsulfinyl, 1, 1-dimethylethylsulfinyl, pentylsulfinyl, 1-methyl-butylsulfinyl, 2-methylbutylsulfinyl, ;" 3-methylbutylsulfinyl, 2,2-dimethylpropylsulfinyl, 1-ethylpropylsulfinyl, 1,1-dimethylpropylsulfinyl, 1,2-dimethylpropylsulfinyl, hexylsulfinyl, 1-methylpentylsulfinyl, 2-methylpentylsulfinyl,

3-methylpentylsulfinyl, 4-methylpentylsulfinyl, 1,1-dimethylbutylsulfinyl, 1,2-dimethylbutylsulfinyl, -I 1,3-dimethylbutylsulfinyl, 2,2-dimethylbutylsulfinyl, 2,3-dimethylbutylsulfinyl, 3,3-dimethylbutylsulfinyl, 1-ethylbutylsulfinyl, 2-ethylbutylsulfinyl, /1,1,2-trimethylpropylsulfinyl,

Me, 1,2,2-trimethylpropylsulfinyl, 1-ethyl-1-methylpropylsulfinyl and 1-ethyl-2-methylpropylsulfinyl; o - C.-Co-haloalkylsulfinyl means the C.-Cv-alkylsulfinyl residue given above, which. partially or completely substituted by fluorine, chlorine, bromine and/or iodine, for example, fluoromethylsulfinyl, i.c. difluoromethylsulfinyl, trifluoromethylsulfinyl, chlorodifluoromethylsulfinyl, bromodifluoromethylsulfinyl,

Ф 2-fluoroethylsulfinyl, 2-chloroethylsulfinyl, 2-bromomethylsulfinyl, 2-iodoethylsulfinyl, 2,2-difluoroethylsulfinyl, 2,2,2-trifluoroethylsulfinyl, 2,2,2-trichloroethylsulfinyl, 2-chloro-2-fluoroethylsulfinyl, 2-chloro -2,2-difluoroethylsulfinyl, 2,2-dichloro-2-fluoroethylsulfinyl, or pentafluoroethylsulfinyl, 2-fluoropropylsulfinyl, 3-fluoropropylsulfinyl, 2-chloropropylsulfinyl,

C-chloropropylsulfinyl, 2-bromopropylsulfinyl, C-bromopropylsulfinyl, 2,2-difluoropropylsulfinyl,

F) 2,3-difluoropropylsulfinyl, 2,3-dichloropropylsulfinyl, 3,3,3-trifluoropropylsulfinyl, ka C,3,3-trichloropropylsulfinyl, 2,2,3,3,3-pentafluoropropylsulfinyl, heptafluoropropylsulfinyl, 1-"(fluoromethyl )-2-fluoroethylsulfinyl, 1-(chloromethyl)-2-chloroethylsulfinyl, 1-(bromomethyl)-2-bromomethylsulfinyl, bo 4-fluorobutylsulfinyl, 4-chlorobutylsulfinyl, 4-bromobutylsulfinyl, nonafluorobutylsulfinyl, 5-fluoropentylsulfinyl, 5-chloropentylsulfinyl -bromopentylsulfinyl, 5-iodopentylsulfinyl, undecafluoropentylsulfinyl, b-fluorohexylsulfinyl, b-chlorohexylsulfinyl, b-bromohexylsulfinyl b-iodohexylsulfinyl and dodecafluorohexylsulfinyl, - Sb.i-C,-alkylsulfonyl and means (C.i-C,-alkyl-Z(- 0O)25-), for example, methylsulfonyl, ethylsulfonyl, 65 propylsulfonyl, 1-methylethylsulfonyl, butylsulfonyl, 1-methylpropylsulfonyl, 2-methylpropylsulfonyl 11,1-dimethylethylsulfonyl,

- C,-C,-alkylsulfonyl means the above C,-C,-alkylsulfonyl, as well as, for example, pentylsulfonyl, 1-methylbutylsulfonyl, 2-methylbutylsulfonyl, 3-methylbutylsulfonyl, 1,1-dimethylpropylsulfonyl, 1,2-dimethylpropylsulfonyl, 2,2- dimethylpropylsulfonyl, 1-ethylpropylsulfonyl, hexylsulfonyl, 1-methylpentylsulfonyl, 2-methylpentylsulfonyl 3-methylpentylsulfonyl, 4-methylpentylsulfonyl, 1,1-dimethylbutylsulfonyl 1,2-dimethylbutylsulfonyl, 1,3-dimethylbutylsulfonyl, 2,2-dimethylbutylsulfonyl, 2, 3-dimethylbutylsulfonyl, 3,3-dimethylbutylsulfonyl, 1-ethylbutylsulfonyl, 2-ethylbutylsulfonyl, 1,1,2-trimethylpropylsulfonyl, 1,2,2-trimethylpropylsulfonyl, 1-ethyl-1-methylpropylsulfonyl | 1-ethyl-2-methylpropylsulfonyl, 70 - C.-C.haloalkylsulfonyl means the C.-C.alkylsulfonyl residue given above, which is partially or completely substituted by fluorine, chlorine, bromine and/or iodine, namely, for example, fluoromethylsulfonyl difluoromethylsulfonyl, trifluoromethylsulfonyl . 2-difluoroethylsulfonyl, 2,2-dichloro-2-fluoroethylsulfonyl, 2,2,2-trichloroethylsulfonyl, pentafluoroethylsulfonyl, 2-fluoropropylsulfonyl, 3-fluoropropylsulfonyl, 2-chloropropylsulfonyl,

C-chloropropylsulfonyl, 2-bromopropylsulfonyl, C-bromopropylsulfonyl, 2,2-difluoropropylsulfonyl, 2,3-difluoropropylsulfonyl, 2,3-dichloropropylsulfonyl, 3,3,3-trifluoropropylsulfonyl, 3,3,3-trichloropropylsulfonyl, 2,2, 3,3,3-pentafluoropropylsulfonyl, heptafluoropropylsulfonyl, (fluoromethyl)-2-fluoroethylsulfonyl, 1-(chloromethyl)-2-chloroethylsulfonyl, 1-(bromomethyl)-2-bromomethylsulfonyl, 4-fluorobutylsulfonyl, 4-chlorobutylsulfonyl, 4-bromobutylsulfonyl And nonafluorobutyl-sulfonyl; - C.-C.halogenalkylsulfonyl means the above C.-C.halogen-alkylsulfonyl residue, as well as, for example, 5-fluoropentylsulfonyl, 5-chloropentylsulfonyl, 5-bromopentylsulfonyl, 5-iodopentylsulfonyl, b-fluorohexylsulfonyl, b-bromohexylsulfonyl, b-iodohexylsulfonyl and dodecafluorohexylsulfonyl, сч - Сб.-С,аlkoxycarbonyl means, for example, methoxycarbonyl, ethoxycarbonyl, propoxycarbonyl, 1-methylethoxycarbonyl, butoxycarbonyl, 1-methylpropoxy-carbonyl, 2-methylpropoxycarbonyl and i) 1,1-dimethoxycarbonyl; - C.-C.halogenalkoxycarbonyl means the above-mentioned C.-C.-alkoxycarbonyl residue, which is partially or completely substituted by fluorine, chlorine, bromine and/or iodine, namely, for example, fluoromethoxycarbonyl, heso-difluoromethoxycarbonyl, trifluoromethoxycarbonyl, chlorodifluoromethoxycarbonyl, bromodifluoromethoxycarbonyl, 2-fluoroethoxycarbonyl, 2-chloroethoxycarbonyl, 2-bromomethoxycarbonyl, 2-iodoethoxycarbonyl, Me 2,2-difluoroethoxycarbonyl, 2,2,2-trifluoroethoxycarbonyl, 2-chloro-2-fluoroethoxycarbonyl, o 2-chloro-2,2-difluoroethoxycarbonyl, 2,2-dichloro-2-fluoroethoxycarbonyl, 2,2,2-trichloroethoxycarbonyl, pentafluoroethoxycarbonyl, 2-fluoropropoxycarbonyl, 3-fluoropropoxycarbonyl, 2-chloropropoxycarbonyl, ise)

3-chloropropoxycarbonyl, 2-bromopropoxycarbonyl, 3-bromopropoxycarbonyl, 2,2-difluoropropoxycarbonyl, 2,3-difluoropropoxycarbonyl, 2,3-dichloropropoxycarbonyl, 3,3,3-trifluoropropoxycarbonyl, 3,3,3-trichloropropoxycarbonyl , 2,2,3,3,3-pentafluoropropoxycarbonyl, heptafluoropropoxycarbonyl, 1-"(fluoromethyl)-2-fluoroethoxycarbonyl, 1-(chloromethyl)-2-chloroethoxycarbonyl, 1-"(bromomethyl)-2-bromomethoxycarbonyl, 4-fluorobutoxycarbonyl . buten-1-yloxy, buten-2-yloxy, buten-3-yloxy, 1-methyl-prop-1-en-1-yloxy, 2-methyl-prop-1-en-1-yloxy, with 1-methyl -prop-2-en-1-yloxy, 2-methyl-prop-2-en-1-yloxy, penten-1-yloxy, penten-2-yloxy, penten-3-yloxy, penten-4-yloxy, 1 -methyl-but-1-en-1-yloxy, 2-methyl-but-1-en-1-yloxy, 3-methyl-but-1-en-1-yloxy, 1-methyl-but-2-ene -1-yloxy, 2-methyl-but-2-en-1-yloxy, 3-methyl-but-2-en-1-yloxy, 1-methyl-but- 3-en-1-yloxy, -I 2-methyl-but-3-en-1-yloxy, 3-methyl-but-3-en-1-yloxy, 1,1-dimethyl-prop-2-en- 1-yloxy, 1,2-dimethyl-prop-1-en-1-yloxy, 1,2-dimethyl-prop-2-en-1-yloxy, 1-ethyl-prop-1-en-2-yloxy, me) 1-ethyl-prop-2-en-1-yloxy, hex-1-en-1-yloxy, hex-2-en-1-yloxy, hex-3-en-1-yloxy, hex-4- en-1-yloxy, o hex-5-en-1-yloxy, 1-methyl-pent-1-en-1-yloxy, 2-methyl-pent-1-en-1-yloxy, 3-methyl-pent -1-en-1-yloxy, 4-methyl-pent-1-en-1-yloxy, 1-methyl-pent-2-en-1-yloxy, 2-methyl-pent-2-en-1-yloxy , se) 3-methyl-pent-2-en-1-yloxy, 4-methyl-pent-2-en-1-yloxy, 1-methyl-pent-3-en-1-yloxy,

F 2-methyl-pent-3-en-1-yloxy, 3-methyl-pent-3-en-1-yloxy, 4-methyl-pent-3-en-1-yloxy, 1-methyl-pent-4 -en-1-yloxy, 2-methyl-pent-4-en-1-yloxy, 3-methyl-pent-4-en-1-yloxy, 4-methyl-pent-4-en-1-yloxy, 1 ,1-dimethyl-but-2-en-1-yloxy, 1,1-dimethyl-but-3-en-i-yloxy, 1,2-dimethyl-but-1-en-1-yloxy, 1,2 -dimethyl-but-2-en-1-yloxy, 1,2-dimethyl-but-3-en-1-yloxy, 1,3-dimethyl-but-1-en-1-yloxy, 1,3-dimethyl -but-2-en-1-yloxy, 1,3-dimethyl-but-3-en-1-yloxy, (F) 2,2-dimethyl-but-3-en-1-yloxy, 2,3- dimethyl-but-1-en-1-yloxy, 2,3-dimethyl-but-2-en-1-yloxy, ka 2,3-dimethyl-but-3-en-1-yloxy, 3,3-dimethyl -but-1-en-1-yloxy, 3,3-dimethyl-but-2-en-1-yloxy, 1-ethyl-but-1-en-1-yloxy, 1-ethyl-but-2-ene -1-yloxy, 1-ethyl-but-3-en-1-yloxy, 2-ethyl-but-1-en-1-yloxy, 2-ethyl-but-2-en-1-yloxy, 2- ethyl-but-3-en-1-yloxy, 1,1,2-trimethyl-prop-2-en-1-yloxy, 1-ethyl-1-methyl-prop-2-en-1-yloxy, 1- ethyl-2-methyl-prop-1-en-1-yloxy and 1-ethyl-2-methyl-prop-2-en-1-yloxy; - C3-C6-alkynyloxy means, for example, prop-1-yn-1-yloxy, prop-2-yn-1-yloxy, but-1-yn-1-yloxy, but-1-yn-3-yloxy, but-1-yn-4-yloxy, but-2-yn-1-yloxy, pent-1-yn-1-yloxy, pent-1-yn-3-yloxy, pent-1-yn-4-yloxy, pent-1-yn-5-yloxy, pent-2-yn-1-yloxy, pent-2-yn-4-yloxy, pent-2-yn-5-yloxy, 65 3-methyl-but-1-yn -3-yloxy, 3-methyl-but-y-yn-4-yloxy, hex-1-yn-1-yloxy, hex-1-yn-3-yloxy, hex-1-yn-4-yloxy, hex -1-yn-5-yloxy, hex-1-yn-6-yloxy, hex-2-yn-1-yloxy, hex-2-yn-4-yloxy,

hex-2-yn-5-yloxy, hex-2-yn-6-yloxy, hex-3-yn-1-yloxy, hex-3-yn-2-yloxy, 3-methylpent-1-yn-1- iloxy,

3-methyl-pent-1-yn-3-yloxy, 3-methylpent-1-yn-4-yloxy, 3-methylpent-1-yn-5-yloxy, 4-methylpent-1-yn-1-yloxy, 4-methylpent-2-yn-4-yloxy and 4-methylpent-2-yn-5-yloxy; - C.-Co-alkylamino means, for example, methylamino, ethylamino, propylamino, 1-methylethylamino, butylamino, 1-methylpropylamino, 2-methylpropylamino, 1,1-dimethylethylamino, pentylamino, 1-methylbutylamino, 2-methylbutylamino, C -methylbutylamino, 2,2-dimethylpropylamino, 1-ethylpropylamino, hexylamino, 1,1-dimethylpropylamino, 1,2-dimethylpropylamino, 1-methylpentylamino, 2-methylpentylamino,

3-methylpentylamino, 4-methylpentylamino, 1,1-dimethylbutylamino, 1,2-dimethylbutylamino, 70 1,3-dimethylbutylamino, 2,2-dimethylbutylamino, 2,3-dimethylbutylamino, 3,3-dimethylbutylamino, 1-ethylbutylamino, 2 -ethylbutylamino, 1,1,2-trimethylpropylamino, 1,2,2-trimethylpropylamino, 1-ethyl-1-methylpropylamino or 1-ethyl-2-methylpropylamino; - di-(Ci-C-alkyl)-amino, as well as dialkylamino-astines of di-(C.--C,-alkyl)aminoimino-C.-C,-alkyl mean, for example, M,M-dimethylamino , M,M-diethylamino, M,M-dipropylamino, M,M-di-(1-methyl-ethyl)amino,

M,M-dibutylamino, M,M-di-(1-methylpropyl)amino, M,M-di-(2-methylpropyl)amino, M,M-di-(1,1-dimethylethyl)amino,

M-ethyl-M-methylamino, M-methyl-M-propylamino, M-methyl-M-(1-methylethyl)amino, M-butyl-M-methylamino,

M-methyl-M-(1-methylpropyl)amino, M-methyl-M-(2-methylpropyl)amino, M-(1,1-dimethylethyl)-M-methylamino,

M-ethyl-M-proptamino, /M-ethyl-M-(1-methylethyl)amino, M-butyl-M-ethylamino, /M-ethyl-M-(1-methylpropyl)amino,

M-ethyl-M-(2-methylpropyl)amino, M-ethyl-M-(1,1-dimethylethyl)amino, M-(1-methylethyl)-M-proptamino,

M-butyl-M-propylamino, M-(1-methylpropyl)-M-propylamino, M-(2-methylpropyl)-M-propylamino,

IM-(1,1-dimethylethyl)-M-propylamino, M-butyl-M-(1-methyl-ethyl)amino, /- M-(1-methylethyl)-M-(1-methylpropyl)amino,

M-(1-methylethyl)-M-(2-methylpropyl)-amino, M-(1,1-dimethylethyl)-M-(1-methylethyl)amino,

M-butyl-M-(1-methylpropyl)amino, M-butyl-M-(2-methylpropyl)amino, M-butyl-M-(1,1-dimethylethyl)amino,

M-(1-methylpropyl)-M-(2-methylpropyl)amino, M-(1,1-dimethylethyl)-M-(1-methylpropyl)amino and sc dv MA(1,1-dimethylethyl)-M-( 2-methylpropyl)amino; - di-(C1-C1-alkyl)amino means the above-mentioned di-(C1-C1-alkyl)amino, as well as M,M-dipentylamino, (8)

M,M-dihexylamino, M-methyl-M-pentylamino, M-ethyl-M-pentylamino, M-methyl-M-hexylamino or

M-ethyl-M-hexylamino. - di-(C.-C.alkyl)C1-Slalkyl means substituted by the above di-(C.4-C.-alkyl)amino C--Slalkyl, namely, "o z For example, M,M-dimethylaminomethyl, M ,M-diethylaminomethyl, M,M-dipropylaminomethyl,

M,M-di-(1-methylethyl)aminomethyl, M,M-dibutylaminomethyl, M,M-di-(1-methylpropyl)aminomethyl, Me)

M,M-di-(2-methylpropyl)aminomethyl, M,M-di-(1,1-dimethylethyl)aminomethyl, M-ethyl-M-methylaminomethyl, o

M-methyl-M-propylaminomethyl, M-methyl-M-(1-methylethyl)aminomethyl, M-butyl-M-methylaminomethyl,

M-methyl-M-(1-methylpropyl)aminomethyl, M-methyl-M-(2-methylpropyl)aminomethyl, ise)

M-(1,1-dimethylethyl)-M-methylaminomethyl, M-ethyl-M-propylaminomethyl, M-ethyl-M-(1-methylethyl)aminomethyl, i-

M-butyl-M-ethylaminomethyl, M-ethyl-M-(1-methylpropyl)aminomethyl, M-ethyl-M-(2-methylpropyl)aminomethyl,

M-ethyl-M-(1,1-dimethylethyl)aminomethyl, /- M-(1-methylethyl)-M-propylaminomethyl, / M-butyl-M-propylaminomethyl,

M-(1-methylpropyl)-M-propylaminomethyl, M-(2-methylpropyl)-M-propylaminomethyl,

IM-(1,1-dimethylethyl)-M-propyl-aminomethyl, M-butyl-M-(1-methylethyl)aminomethyl, " 40. M-(1-methylethyl)-M-(1-methylpropyl)aminomethyl, M -(1-methylethyl)-M-(2-methylpropyl)aminomethyl, with М-(1,1-dimethylethyl)-M-(1-methylethyl)aminomethyl, M-butyl-M-(1-methylpropyl)aminomethyl,

M-butyl-M-(2-methylpropyl)aminomethyl, M-butyl-M-(1,1-dimethylethyl)aminomethyl, ; » M-(1-methylpropyl)-M-(2-methylpropyl)aminomethyl, M-(1,1-dimethylethyl)-M-(1-methylpropyl)aminomethyl,

M-(1,1-dimethylethyl)-M-(2-methylpropyl)aminomethyl, 2-(M,M-dimethylamino)-ethyl, 2-(M,M-dimethylamino)ethyl, 2-(M,M-dipropylamino) )-ethyl, 2-IM,M-di-(1-methylethyl)amino|ethyl, 2-IM,M-dibutylamino|ethyl, -I 2-IM,M-di-(1-methylpropyl)amino|ethyl, 2-IM,M-di-(2-methylpropyl)amino|ethyl, 2-IM,M-di-(1,1-dimethylethyl)amino|ethyl, 2-(M-ethyl-M-methylamino|ethyl, 2 -I(M-methyl-M-propylamino|ethyl,

Me, 2-IM-methyl-M-(1-methylethyl)amino|ethyl, 2-(M-butyl-M-methylamino|ethyl, 2-IM-methyl-M-(1-methylpropyl)amino|ethyl, o 2-I(M-methyl-M-(2-methyl-propyl)amino|ethyl, 2-(M-(1,1-dimethylethyl)-M-methylamino|ethyl, boro 2-1M-ethyl-M-propylamino |ethyl, 2-(M-ethyl-M-(1-methylethyl)amino|ethyl, 2-N-butyl-M-ethylamino|ethyl, ik 2-(M-ethyl-M-(1-methylpropyl)amino| ethyl, 2-N-ethyl-N-(2-methylpropyl)amino|ethyl,

Ф 2-IM-ethyl-M-(1,1-dimethylethylamino|ethyl, 2-IM-(1-methylethyl)-M-proptamino|ethyl, 2-IM-butyl-M-propylamino|ethyl, 2-IM- (1-methylpropyl)-M-propylamino|ethyl, 2-(M-(2-methylpropyl)-M-propylamino|ethyl, 2-IM-(1,1-dimethylethyl)-M-propylamino|ethyl, 2-( M-butyl-M-(1-methyl-ethyl)amino|ethyl, two 2-II-A(1-methylethyl)-M-(1-methyl-propyl)amino|ethyl, 2-(M-(1- methylethyl)-M-(2-methylpropyl)amino|ethyl, 2-IM-(1,1-dimethylethyl)-M-(1-methylethyl)amino|ethyl, 2-IM-butyl-M-(1-methylpropyl) amino|ethyl,

Ф) 2-IM-butyl-M-(2-methylpropyl)amino|ethyl, 2-I(M-butyl-M-(1,1-dimethylethyl)amino|ethyl, ka 2-IM-(1-methylpropyl) -M-(2-methylpropyl)amino|ethyl, 2-(IM-(1,1-dimethyl-ethyl)-M-(1-methylpropyl)amino|ethyl, 2-(M-(1,1-dimethylethyl) -M-(2-methylpropyl)amino|)ethyl, 3-(M,M-dimethylamino)propyl, 3-(M,M-diethylamino)propyl, and 4-(M,M-dimethylamino)butyl and 4 -(M,M-diethylamino)butyl; - C4-C.alkyl means substituted by the above-mentioned C.-C.-alkyl-residue C.-C.-alkyl, namely, methoxymethyl, ethoxymethyl, propoxymethyl, (1-methylethoxy)methyl , butoxymethyl, (1-methylpropoxy)methyl, (2-methylpropoxy)methyl, (1,1-dimethylethoxy)methyl, 2-(methoxy)ethyl, 2-(ethoxy)ethyl, 2-(propoxy)ethyl, 2-( 1-methylethoxy)ethyl, 2-(butoxy)ethyl, 2-(1-methylpropoxy)ethyl, 2-(2-methylpropoxy)ethyl, 65 2-(1,1-dimethylethoxy)ethyl, 2-(methoxy)propyl 2 -(ethoxy)propyl, 2-(propoxy)propyl, 2-(1-methylethoxy)propyl, 2-(butoxy)propyl, 2-(1-methylpropoxy)propyl, 2-(2-methylpropoxy)propyl, 2-( 1,1-dimethyl-ethoxy)propyl,

3-(methoxy)propyl, 3-(ethoxy)propyl, 3-(propoxy)propyl, 3-(1-methylethoxy)propyl, 3-(butoxy)propyl, 3-(1-methylpropoxy)propyl, 3-( 2-methylpropoxy)propyl, 3-(1,1-dimethylethoxy)propyl, 2-(methoxy)-butyl, 2-(ethoxy)butyl, 2-(propoxy)butyl, 2-(1-methylethoxy)butyl, 2- (butoxy)butyl, 2-(1-methylpropoxy)butyl, 2-(2-methylpropoxy)butyl, 2-(1,1-dimethylethoxy)butyl, 3-(methoxy)butyl, 3-(ethoxy)butyl, 3- (propoxy)-butyl, 3-(1-methylethoxy)butyl, 3-(butoxy)butyl, 3-(1-methylpropoxy)-butyl, 3-(2-methylpropoxy)butyl, 3-(1,1-dimethylethoxy) butyl, 4-(methoxy)-butyl, 4-(ethoxy)butyl, 4-(propoxy)butyl, 4-(1-methylethoxy)butyl, 4-(butoxy)butyl, 4-(1-methylpropoxy)butyl, 4 -(2-methylpropoxy)butyl and 4-(1,1-dimethylethoxy)butyl; - C.-Alkylthio-C4-C;.alkyl means substituted by the above C.-C,alkylthio C--C,.alkyl, namely, for example, 7/0 Mmethylthiomethyl, ethylthio-methyl, propylthiomethyl, (1-methylethylthio) methyl, butylthiomethyl, (1-methylpropylthio)methyl, (2-methylpropylthio)methyl, (1,1-dimethylethylthio)methyl, 2-methylthioethyl, 2-ethylthioethyl, 2-(propylthio)ethyl, 2-(1-methylethylthio)ethyl , 2-(butylthio)ethyl, 2-(1-methylpropylthio)ethyl, 2-(2-methylpropylthio)ethyl, 2-(1,1-dimethylethylthio)ethyl, 2-(methylthio)propyl, 3-(methylthio)propyl , 2-(ethylthio)propyl, 3-(ethylthio)propyl,

C-(propylthio)propyl, C-(butylthio)propyl, 4-(methylthio)butyl, 4-(ethylthio)butyl, 4-(propylthio)butyl and . 75. 4-("butylthio)butyl; - C.-C.-alkyl means C.-C.-alkyl substituted by C.-C.-alkyl-carbonyl, namely, for example, methoxycarbonylmethyl, ethoxycarbonylmethyl, propoxycarbonylmethyl, (1-methylethoxycarbonyl)methyl, butoxycarbonylmethyl, (1-methylpropoxycarbonyl )methyl, (2-methylpropoxycarbonyl)methyl, (1,1-dimethylethoxycarbonyl)methyl, 2-(methoxycarbonyl)ethyl, 2-(ethoxycarbonyl)ethyl, 2-(propoxy-carbonyl)ethyl, 2-(1-methylethoxycarbonyl)ethyl , 2-(butoxycarbonyl)ethyl, 2-(1-methylpropoxycarbonyl)ethyl, 2-(2-methylpropoxycarbonyl)ethyl, 2-(1,1-dimethylethoxycarbonyl)ethyl, 2-(methoxycarbonyl)propyl, 2-(ethoxycarbonyl)propyl , 2-(propoxycarbonyl)propyl, 2-(1-methylethoxycarbonyl)propyl, 2-(butoxycarbonyl)propyl, 2-(1-methylpropoxycarbonyl)propyl, 2-(2-methylpropoxycarbonyl)propyl, 2-(1,1-dimethylethoxycarbonyl) )propyl, 3-(methoxycarbonyl)-propyl, 3-(ethoxycarbonyl)propyl, sch

3-(propoxycarbonyl)propyl, 3-(1-methylethoxycarbonyl)propyl, 3-(butoxycarbonyl)propyl, 3-(1-methylpropoxycarbonyl)propyl, 3-(2-methylpropoxycarbonyl)propyl, 3-(1,1-dimethylethoxycarbonyl) propyl, and) 2-(methoxycarbonyl)butyl, 2-(ethoxycarbonyl)butyl, 2-(propoxycarbonyl)butyl, 2-(1-methylethoxycarbonyl)butyl, 2-(butoxycarbonyl)butyl, 2-(1-methylpropoxycarbonyl)butyl, 2-(2-methylpropoxycarbonyl)butyl, 2-(1,1-dimethylethoxycarbonyl)butyl, 3-(methoxycarbonyl)butyl, 3-(ethoxycarbonyl)butyl, "o zo 3-(propoxycarbonyl)butyl, 3-(1-methylethoxy -carbonyl)butyl, 33-(butoxycarbonyl)butyl, 3-(1-methylpropoxycarbonyl)butyl, 3-(2-methylpropoxycarbonyl)butyl, / 3-(1,1-dimethylethoxycarbonyl)butyl, Me 4-(methoxycarbonyl)butyl, 4-(ethoxycarbonyl)butyl, 4-(propoxycarbonyl)butyl, 4-(1-methylethoxycarbonyl)butyl, s 4-(butoxycarbonyl)butyl, 4-(1-methylpropoxy)butoxy, 4-(2-methylpropoxy)butoxy and 4 -(1,1-dimethylethoxycarbonyl)butyl; ise) - C, -C, Alkoxy-C, C, Alkoxy means the above C, and -C, -Alkoxy C, -C, -Alkoxy, for example, 1- 2-(methoxy)ethoxy, 2-(ethoxy)ethoxy, 2-(propoxy)ethoxy, 2-(1-methylethoxy)ethoxy, 2-(butoxy)ethoxy, 2-(1-methylpropoxy)ethoxy, 2-(2-methylpropoxy)ethoxy, /2-(1,1-dimethylethoxy )ethoxy, 2-(methoxy)propoxy, 2-(ethoxy)propoxy, 2-(propoxy)propoxy, 2-(1-methylethoxy)propoxy, 2-(butoxy)propoxy, 2-(1-methylpropoxy)propoxy, 2 -(2-methylpropoxy)propoxy, 2-(1,1-di'zmethylethoxy)propoxy, "

3-(methoxy)-propoxy, 3-(ethoxy)propoxy, 3-(propoxy)propoxy, 3-(1-methylethoxy)propoxy, sv) with 3-(butoxy)propoxy, 3-(1-methylpropoxy)propoxy, 3-(2-methylpropoxy)propoxy, . 3-(1,1-dimethylethoxy)propoxy, 2-(methoxy)butoxy, 2-(ethoxy)butoxy, 2-(propoxy)butoxy, and? 2-(1-methylethoxy)butoxy, 2-(butoxy)-butoxy, 2-(1-methylpropoxy)butoxy, / 2-(2-methylpropoxy)butoxy, 2-(1,1-dimethylethoxy)butoxy, 3-( methoxy)butoxy, 3-(ethoxy)-butoxy, 3-(propoxy)butoxy, 3-(1-methylethoxy)butoxy, 3-(butoxy)butoxy, 3-(1-methylpropoxy)butoxy, 3-(2-methylpropoxy) )butoxy, -I 3-(1,1-dimethylethoxy)butoxy, 4-(methoxy)-butoxy, 4-(ethoxy)butoxy, 4-(propoxy)butoxy, 4-(1-methylethoxy)butoxy, 4-( butoxy)butoxy, 4-(1-methylpropoxy)butoxy, 4-(2-methylpropoxy)butoxy and me)4-(1,1-dimethylethoxy)butoxy; o - Co-Csalkanedyl means, for example, ethane-1,2-diyl, propane-1,33-diyl, butane-1,4-diyl, pentane-1,5-diyl and hexane-1,6-diyl; ik - C3-Ce-cycloalkyl: 2.8. cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl;

Ф - C3--Svacycloalkyl means the above C3-Secycloalkyl, as well as cycloheptyl or cyclooctyl.

All phenyl rings are preferably unsubstituted or have from one to three halogen atoms, a mAb or a nitro group, a cyano residue and/or one or two methyl, trifluoromethyl, methoxy or two trifluoromethoxy substituents.

Taking into account the use of the declared compounds of formula I as herbicides, the substituents have the desired effect

F) variant has the following values, namely, separately and in combination. ko B", 2 means nitro, halogen, cyano, C.-Cvalkyl, C.-Cvhaloalkyl, C.-Cv-Alkoxy,

C.-Svhaloalkyloxy, C.-Svalkylthio, S.-Svhalogen-alkylthio, S.i-Svalkylsulfinyl, C.-Svhalogenalkylsulfinyl, because S.i-Svalkyl-sulfonyl or C.-Svhalogenalkylsulfonyl; particularly preferred are nitro, halogen, such as chlorine and bromine, C-Salkyl, such as methyl and ethyl, C-Swealkoxy, such as methoxy and ethoxy,

C-S-haloalkyl, such as difluoromethyl and trifluoromethyl, C 4-C-alkylthio, such as methylthio and ethylthio, C-Salkylsulfinyl, such as methylsulfinyl and ethylsulfinyl, C-Salkylsulfonyl, such as .

EZ hydrogen;

In hydrogen; ve", o hydrogen, halogen, iano, nitro, S.-Salkyl, S.-Salkoxy-S.-S.-alkyl, 17A tA 1

C.-C,-Alkoxycarbonyl-C.-Alkyl, C.-C.Alkylthio-C.-C.-Alkyl, C.-C.haloalkyl, C.-C.cyanoalkyl, C.-C.cycloalkyl, C.-C ;Alkoxy, C.i-C,Alkoxy-Co-C,Alkoxy, C.C.-C.Haloalkyloxy, C.-Salkylthio,

C.i.-C.haloalkylthio, di-(C.-C.,-alkyl)amino, owl, phenyl or benzyl, and both of the latter substituents may be partially or fully halogenated and/or may have from one to three such groups : nitro, cyano, C4-Alkyl, C1-C1haloalkyl, C1-C; substituted by 276 70 C.-C.alkyl and/or can be interrupted by optionally substituted C.-C.-alkyl nitrogen; in a particularly preferred embodiment, KO means hydrogen, halogen, cyano, nitro, C.-C.alkyl, C.-C., alkoxy-C.-C.-alkyl, C.-C.,-alkyl-carbonyl-C.4-C.alkyl. C.-C.-alkylthio-C.--C;alkyl, C.-Subhaloalkyl, C.-C.cyanoalkyl,

C3-Cv-cycloalkyl, C.i-C;Alkoxy, C.I-C.Alkoxy-Co-C,Alkoxy, C.-C.Haloalkyl, C.-Sulfylthio,

C.i.-C.haloalkylthio, di-(C.-C.-alkyl)amino, owl, phenyl or benzyl. Moreover, both of the latter substituents may be partially or fully halogenated and/or may have from one to three of the following groups: nitro, cyano, C-C alkyl, C-C haloalkyl, C-C alkoxy or C-C. haloalkoxy; in particular, in the preferred version, KU means hydrogen or S.-Salkil; especially desirable KZ means hydrogen, S.-Salkil,

C.-C.haloalkyl, C.-C.alkoxycarbonyl or C.O., especially preferably KZ means hydrogen or C.-Slalkyl; in the optimal version, KU means hydrogen or C.-C.sub.6-alkyl, especially hydrogen; in the optimal version, B means hydrogen;

B means halogen, C.i-Svalkyl, C.-Svhaloalkyl, C.i-Svaloxy, C.-Svalkylthio, C.-Svalkylsulfinyl,

C.-C alkylsulfonyl, amino, C.-Salkylamino, di-(C.sub.1-C.sub.6-alkyl)amino, di-(C.sub.1-C.sub.6-alkyl)methyl or sov; especially preferably C.-C.alkyl, such as, for example, methyl, ethyl, 1-methylethyl or 1,1-dimethylethyl, hydroxycarbonyl or C.-C.,-alkoxycarbonyl, such as, for example, methoxycarbonyl or ethoxycarbonyl; at

VZ means C-Slalkyl, hydroxy, C-Slalkoxy or MAUV 9;

VE? hydrogen or S.-Salkil; vya s.-C,-alkyl; (Se) in'? hydrogen, C.-C.alkyl, C.-C.halogenalkyl, C.-C.alkylcarbonyl, C.-C.halogenalkylcarbonyl, Fo

C.-C alkylsulfonyl, C.4-C.sup.-haloalkylsulfonyl, phenyl, benzyl, phenylcarbonyl or phenyl or phenylsulfonyl, and the phenyl residue of the five last-mentioned substituents is partially or fully halogenated and/or o may have from one to three such groups : nitro, cyano, C--Slalkyl, S--Slahaloalkyl, C--C,-Alkoxy or He

C.-C. haloalkoxy; hydrogen, C.4-C.alkyl, C.4-C.-alkylsulfonyl, C.4-C.haloalkylsulfonyl, 32 phenyl, benzyl or phenylsulfonyl are particularly preferred, and the phenyl residue of the last three substituents may be partially or fully halogenated and /or may have from one to three of the following groups: nitro, cyano,

C1-C1 alkyl, C1-C1 haloalkyl, C4-C1 alkyl or C1-C1 haloalkyl; in particular, preferably means hydrogen or C,-C,-alkylsulfonyl, C,-C,haloalkylsulfonyl or "phenylsulfonyl, and the phenyl residue may be partially or fully halogenated and/or may have - from one to three such groups nitro, cyano, C.-C.alkyl, C.-C.haloalkyl, C.i.-C., .alkyloxy or C.-C.haloalkyl; "» especially preferably hydrogen, C.--C; alkyl, C.--C,-alkylsulfonyl, C.-C.haloalkylsulfonyl, thienylmethyl, "phenyl, benzyl, phenylsulfonyl or phenylcarbonylmethyl, and the phenyl residue of the last four substituents may be partially or fully halogenated and/or may have from one to three of the following -1 45 groups: nitro, cyano, C--Sulfalkyl, C4-C/haloalkyl, C-Slalkoxy or C-C-halogen-alkoxy;

BZ C.4-Cv-alkyl or Ca-Cv-cycloalkyl; especially preferably methyl, ethyl, 1-methylethyl or 1,1-dimethylethyl or

Ge) cyclopropyl; o B" is hydrogen or C-C-C-alkyl; hydrogen or methyl is particularly preferred.

The following forms of execution of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of the formula I should be especially highlighted: (Ce) 1. In the desired form of execution of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of the formula

F B" means nitro, halogen, C 1 -C 1 alkyl, C 1 -C 1 -haloalkyl, C 1 -C 1 alkyl, or C 1 -C 2 -haloalkyl; especially preferred is nitro, halogen, such as chlorine or bromine, C 1 -C 1 -alkyl, such as methyl or ethyl,

C.-C.haloalkyl, such as difluoromethyl or trifluoromethyl, C.i.-C.alkyl, such as methoxy or ethoxy, or

C.-C. haloalkoxy, such as difluoromethoxy or trifluoromethoxy; in particular, halogen, such as chlorine or bromine, C1-C6 alkyl, such as methyl or ethyl, or C1-C6 alkoxy, such as methoxy or ethoxy; (F; preferably halogen, such as chlorine or bromine, C.-C.alkyl, such as methyl or ethyl; 2 means halogen, C.-Swhaloalkyl, C.-Swalkylthio, C.-Swhaloalkylthio, C.-- Swalkylsulfinil, 1756 16 16 16

C.-C.halogenalkylsulfinyl, C.-C-alkylsulfonyl or C.-C.halogenalkylsulfonyl; 17-6 17-6 17-46 is particularly preferably halogen, such as fluorine or chlorine, C 4-C, haloalkyl, such as difluoromethyl or trifluoromethyl, or C,-C,-alkylsulfonyl, such as methylsulfonyl or ethylsulfonyl; in particular, means halogen, such as fluorine or chlorine, or C1-C1-alkylsulfonyl, such as methylsulfonyl or ethylsulfonyl. 2. In another preferred embodiment of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of formula 65, BZ means hydrogen. 3. In another preferred embodiment of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of the formula

VZ means halogen or S.-Salkyl; in particular, chlorine or methyl. 4. In another preferred embodiment of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of the formula

B" means hydrogen; vo means hydrogen, halogen, cyano, nitro, S.-Sualkyl, S.-Salcoxy-S.-Salkyl,

C.-C alkoxycarbonyl-C,-C,alkyl, C.-C.alkylthio-C.-C.-alkyl, C.-C.haloalkyl, C.-C.cyanoalkyl,

C3-Swcycloalkyl, C.-C,-Alkoxy, C4-SlalkoxyCo-C,Alkoxy, C.-C.haloalkyl, C.-C.-Alkylthio,

C.-Chaloalkylthio, di(C.--Cu-alkyl)amino, C.-C.-alkylcarbonyl, C.4-Slalkoxycarbonyl, SOMAULO, phenyl or benzyl, and both of the latter substituents may be partially or fully halogenated and/ or may have from one to three of the following groups: nitro, cyano, C--Slalkyl, C1-C1-haloalkyl, C1-C1-alkyl, or

C.-C. haloalkoxy; especially preferably, hydrogen, C.4-C.alkyl, C--C.haloalkyl, C.-C.alkoxycarbonyl or SOMC zdo. in particular, hydrogen or C-C alkyl such as methyl or ethyl; in the optimal version, hydrogen: 75 25 means hydrogen or C-alkyl, such as methyl or ethyl; hydrogen is particularly preferred. 5. In another preferred embodiment of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of the formula

B means halogen, C.--Cvalkyl, C.--Cvhaloalkyl, C.i-Cvalkyl, C.-Cv-alkylthio, C.--Cvalkylsulfinyl,

C.-C alkylsulfonyl, amino, C.i-Cv-alkylamino, di-(Ci-Cv-alkyl)damino, di(C--Svaloxy)methyl, formyl,

C.-C.alkylcarbonyl, C.-C.haloalkylcarbonyl, hydroxycarbonyl, C.-C.alkoxycarbonyl, C.-C.halogenalkoxycarbonyl or SOMAUV o; particularly preferably, halogen such as chlorine or bromine, C 1 -C 1 -alkyl such as methyl, ethyl, 1-methylethyl or 1,1-dimethylethyl, C 1 -C 1 -alkyl such as methoxy or ethoxy,

C, -C, alkylthio, such as methylthio or ethylthio, C, -C, alkylsulfinyl, such as methylsulfinyl or ethylsulfinyl, C, -C, alkylsulfonyl, such as methylsulfonyl or ethylsulfonyl, amino, C -- C, alkylamino, such as methylamino or ethylamino, di-(C 4-C, -alkyl)uamino, such as dimethylamino or diethylamino, Ge! di(C 1 -C 1 -alkoxy)methyl, such as dimethoxymethyl or diethoxymethyl, C .--C;alkylcarbonyl, such as o methylcarbonyl or ethylcarbonyl, hydroxycarbonyl,

C.-C.Alkoxycarbonyl, such as methoxycarbonyl or ethoxycarbonyl or COM 9; especially preferably C1-C6 alkyl, such as methyl, ethyl, 1-methylethyl or 1,1-dimethylethyl, hydroxycarbonyl or C1-C1-alkoxycarbonyl, such as methoxycarbonyl or ethoxycarbonyl; |se) in the optimal version, C.-C. alkyl, such as methyl, ethyl, 1-methylethyl or 1,1-dimethylethyl; Fo 6. In another preferred embodiment of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of the formula v'? means C.-Alkyl, C.-C.haloalkyl, C.-C.alkylcarbonyl, C.-C.haloalkylcarbonyl, o

C.-C.alkylsulfonyl, C1-C1haloalkyl-sulfonyl, phenyl, benzyl, phenylcarbonyl or phenylsulfonyl, and the He phenyl residue of the last four substituents given may be partially or fully halogenated or may have from one to three of the following groups: nitro, cyano, Si -C.-Alkyl, C.-C.haloalkyl, C.-C.,.Alkoxy or -

C.-C. haloalkoxy; preferably C-C alkyl, C 1-C alkylsulfonyl, C 4-C haloalkylsulfonyl, phenyl, benzyl or phenylsulfonyl, and the phenyl residue of the last three substituents may be partially or fully halogenated and/or may have from one to three such groups : nitro, cyano, C.-C; alkyl, "

C.-Shaloalkyl, C.i-Sl.Alkoxy or C.-Shalogenalkoxy; especially preferably /C.-C.alkylsulfonyl, - 70 C.-C.haloalkylsulfonyl or phenylsulfonyl, and the phenyl residue may be partially or fully halogenated and/or may have from one to three of the following groups: nitro, cyano, C.- C,-alkyl, C.--C.haloalkyl, C.i-C;-alkyl or C.-C.haloalkyl; also in a particularly preferred variant means benzyl, and the phenyl residue may be partially or fully halogenated and/or may have from one to three of the following groups: nitro, cyano, C-C alkyl,

C.-C.haloalkyl, C.-C.alkoxy or C.-C.haloalkyl. and 7. In another preferred embodiment of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles. of formula (o) B" means C.sub.-Sulalkyl, C.sub.3-Sulylquinyl, thienylmethyl, benzyl, phenylcarbonyl, phenylsulfonyl or phenyl o carbonyl methyl, and the phenyl residue of the last four substituents may be partially or fully halogenated and/or may have from one up to three of the following groups: nitro, cyano, C1-C4alkyl, se) 20 C1-C4-haloalkyl, C1-C4-alkyl or C1-C4-haloalkyl, preferably thienylmethyl such as 3-thienylmethyl ,

F is benzyl, phenylcarbonyl, phenylsulfonyl, or phenylcarbonylmethyl, and the phenyl residue of the last four substituents may be partially or fully halogenated and/or may have one to three of the following groups: nitro, cyano, C-C alkyl, C4-C haloalkyl, C4-C;.Alkoxy or C.-C.Haloalkoxy. in 8. In another preferred embodiment of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of formula I, K 72 means hydroxy. (F) 9. In another preferred form of execution of -3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of formula ka BZ means C,-C,-alkyl, such as methyl, ethyl, methylethyl or 1,1 -dimethylethyl or C .-Seccycloalkyl, such as cyclopropyl; 60 is preferably C1-C1 alkyl, such as methyl, ethyl, 1-methylethyl or 1,1-dimethylethyl; especially desirable

C3-Secycloalkyl, such as cyclopropyl;

B" means hydrogen or C.-C.alkyl, such as, for example, methyl or ethyl; especially preferably hydrogen or methyl; 10. In another preferred embodiment of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of the formula And 65 V" means halogen, C4-Slalkyl or C.-Slalkoxy; K? means halogen or C-Slalkylsulfonyl; VU, VK" and 5 mean hydrogen;

VE? means hydrogen or S.-Salkil; especially hydrogen

B stands for C 1 -C 1 -alkyl, di(C 1 -C 1 -hydroxy)methyl, hydroxycarbonyl or C 1 -C 1 -hydroxycarbonyl; 72 means hydrogen, Ca3-C.-alkynyl, thienylmethyl, benzyl, phenylcarbonyl phenylsulfonyl or phenylcarbonylmethyl, and the phenyl residue of the last four substituents may be partially or fully halogenated and/or may have from one to three such nitro, cyano, C groups. -C, alkyl,

C.-C.haloalkyl, C.-C;.

BZ stands for C.-Slalkyl, C.4-S.haloalkyl or cyclopropyl, in particular C.-C;alkyl or cyclopropyl, 2"I means hydrogen, C.-C.alkyl or cyclopropyl, in particular hydrogen or C.-C,alkyl. then In particular, 3-(4,5-dihydroisoxazol-5-yl)/benzoyl-pyrazoles of the formula Iai (where K'/ - SI, K2 - 50, СНа, ВЗ, Вы, КК Н, КЗ - СНУ) are especially desirable compounds from Iai 1 to Ia! 64, and the residues from VK" to Vya not only in combination with each other, but also each separately have a special meaning for the invention that is claimed.

Yi : Yii Ne Ma, ; And where

I Zn | Oct. . KZ

There is a high school

F

» F o

F zv in " o - - i" 5 z

F o u

F

5 o yu zo bo ivy.34| СНо-СНо-СНо-СНо sleep

; yu

I'm sorry

F from F o

F

- compounds Ia?2, in particular, compounds Ia2.1-Ia2.64, which differ from compounds

Ia1.1-Ia1.b4 that В "З means ethyl. -я. В | НЯ « skh et is Ж y Z s 70 svy uv zh she de ta? г" schi. As: И С : в

T he | spring,

B, S. b Also, in particular, compounds IaZ, especially compounds IaZ3.1-Ia.64, which differ from compounds (a) Ia1.1-Ia1.64 in that VK "Z means isopropyl o M. in I took her

I can bear with

Also, in particular, compounds Ia4, especially compounds Ia4.1-Ia4.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that K"Z means tert.-butyl b5

Z. p a 7 |. | pe | I'm a widow sha o an: tab / ni ve Chek; schih B A CHYN

Also, in particular, compounds Iab5, especially compounds Iab5.1-Ia5.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that "B" means the methyl group of the first line: PN ZK

Mesyur kN sho. Bya sne 8, what about God's SLEEP;

Also, in particular, compounds Iab, especially compounds Iab.1-Iab.64, which differ from compounds (22) are desirable

Ia1.1-Ia1.64 by the fact that KZ means ethyl and B? means methyl.

Shchy : and Riist che and V | tv and I 5 z z May Vsh annii 7 ; io 700 voBosh ek, y sh Sov

He" Also desirable are, in particular, compounds Ia7, especially compounds Ia7.1-Ia7.64, which differ from compounds about Ia1.1-Ia1.64 in that B": means isopropyl and B"" means methyl. d. "in and ' and I I M " "In and OO oh yu shi shiy you I viv,

SPISN) with:

Also desirable are, in particular, compounds Ia, especially compounds Ia8.1-Ia8.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that KZ means tert.-butyl and B" means methyl. b5 and off di i 70 Kok sa NY ev SHI Ve k 7 - "EVEN nah i pu. ; that t Also desirable are, in particular, compounds Ia9, especially compounds Ia9.1-Ia9.64, which differ from compounds

Ia1.1-Ia1.64 because EV! means methyl. what ОВ я о OST dyny re 7 І Іі Ше І Х і | s 00 Mer IY sh o it ee so yu Si her

Also desirable are, in particular, compounds Ia10, especially compounds Ia10.1-Ia10.64, which differ from compounds

And 1:p1iz (ав) а1.1-(а1.64 by the fact that K' means methyl and K " means ethyl. pos: CHYNY ,. shi che i" 10980000 BbSNu i le: щ Kon:

Ф Also desirable are, in particular, compounds Ia11, especially compounds Ia11.1-Ia11.64, which differ from compounds "in Ia1.1-Ia1.64 in that B" means methyl and K C means isopropyl in

OS melon « Zh zh yan yaev dad

Honey; sna Ok and She sita yah yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu yu what

CH(CH3Z3 65) Also desirable are, in particular, compounds Ia12, especially compounds Ia12.1-Ia12.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl AND B C means tert-butyl.

ka On gay kl sen

І 4 e Vogolya ly і і п ю Mody і t Also desirable are, in particular, compounds Ia13, especially compounds Ia13.1-Ia13.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! | E"" means methyl. и вой кише о ди 29 и и ши; y z What Z "r d)

Se 1 same Y I Iv I - so u SCHO un vodnu; F uch ha

Also desirable are, in particular, compounds Ia14, especially compounds Ia14.1-Ia14.64, which differ from compounds o

Ia1.1-Ia1.64 by the fact that B" and B"? mean methyl and КВ "Z means ethyl. re) and ti Sh and

OO bnu j oy du U sia y schi y zh nk. KU "m ydeeesy V. e K y I. z "z IY b: : sya sh, ry: Shu vshei vh s she: shi :

Yi Chi Son.

Also desirable are, in particular, compounds Ia15, especially compounds Ia15.1-Ia15.64, which differ from compounds

Ia1.1-Ia1.64 in that B and B" mean methyl and KZ means isopropyl. o 50 o Z shori i ki ee HO taya 65 Also desirable are, in particular, compounds Ia1b6, especially compounds Ia16.1-Ia16. 64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? mean methyl and KE "Z means tert.-butyl.

her St. E. t s ozh z not OT o

M. Y. A t e t mn "7 Ves sna ro

Also desirable E, in particular, compounds Ia17, especially compounds Ia17.1-Ia17.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means trifluoromethyl. t ge p tya b sv dey

WHERE: in St. Shiya and I Ki sr SCHI zni tai7. kl Ya Gi "dv s p NN ee

Shit

Also desirable are, in particular, compounds Ia18, especially compounds Ia18.1-Ia18.64, which differ from compounds Ia

Ia1.1-Ia1.64 by the fact that B! means trifluoromethyl and B "Z means ethyl. av! that 5 (Te; pl

Y: and in! ! and drink; rya t their dogs dog subtyattt ba te I still Tai

Y pssskiy s- y " tv i m t, Kot M y t. " 7 Жмк ШЕ s o z - ..

Also desirable are, in particular, compounds Ia19, especially compounds Ia19.1-Ia19 64, which differ from compounds b Ia1.1-Ia1.64 in that B" means trifluoromethyl and KZ means isopropyl. o 50 va; b -k ke і что En Z что Виши Бня s, бикс Ка я aa что ЗЕ ИЙ Р | тий ю 4 On. zeeSYz. 60 SNysneo

Also desirable are, in particular, compounds Ia20, especially compounds Ia20.1-Ia20.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means trifluoromethyl and B C means tert-butyl. b5 not Bk with . and | and. at. that J and sisns 5.

Also desirable are, in particular, compounds Ia21, especially compounds Ia21.1-Ia21,64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means trifluoromethyl and KE"? means methyl. and St. with the same 000 EC

Sho ya bang gu. - and neck ps Y pa I e I I se t Her "ve o

TE "Yana and z y roya be ne SHU skot ney pi ch ie; she: і"

Also desirable are, in particular, compounds Ia22, especially compounds Ia22.1-Ia22.64, which differ from compounds o

Ia1.1-Ia1.64 by the fact that B" means trifluoromethyl, K "Z means ethyl and BK"! means methyl. ise) what SHY else: p. im same v. bno M. .. i and and ЕЙ Y ns IS

Not: п и Й .и | and What and | pe govkiedi « ev me mi yiv28 y breya il y NYA 15 y etc. rods -: U sh KE shsh with Moss and pk: SHY KE shchi 7 Sh with Son

Ф Also desirable are, in particular, compounds Ia23, especially compounds Ia23.1-Ia23.64, which differ from compounds (in Ia1.1-Ia1.64 in that B" means trifluoromethyl, VK "Z means isopropyl, and K" ? means methyl.-

F OBZH, where are we?

NO. axis and child neo, HB TV23. t Zh. s with iy h shk. "y x Wei -- to. , I will go to bed

Also desirable are, in particular, compounds Ia24, especially compounds Ia24.1-Ia24.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means trifluoromethyl, B C means tert.-butyl and B" means methyl. b5 b shk.

ОО ЭБх дын with more. and zhisiv AK SYNI sno "Em s yy skh chi shov "In Ye schy yy : El b that "v y esh ;, y I A Te SYN and y I zn 7 vbev, t Also desirable are, in particular, compounds Ia25, especially compounds Ia25.1-Ia25.64, which differ from compounds

Ia1.1-Ia1.64 because EV! means methoxy. 2 0 Osn dey, I 30 check, F

Also desirable are, in particular, compounds Ia26, especially compounds Ia26.1-Ia26.64, which differ from compounds av!

Ia1.1-Ia1.64 by the fact that B! means methoxy and B C means ethyl. with 35 p. or "KZ i-

What are you? Today I ate 45.

Also desirable are, in particular, compounds Ia27, especially compounds Ia27.1-Ia27.64, which differ from compounds about Ia1.1-Ia1.64 in that B" means methoxy and K 3 means isopropyl. 50 (se) that uk in

Every other day: y. i shchei p. | . Also desirable are, in particular, compounds Ia28, especially compounds Ia28.1-Ia28.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methoxy and B C means tert-butyl. and OS Fr

Also desirable are, in particular, compounds Ia29, especially compounds Ia29.1-Ia29.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that "B" means methoxy and KE? means methyl.

Ka. Osn di Yasha

Medici 0 from Zhe - write Ge)

Also desirable are, in particular, compounds IaZO, especially compounds IaZ30.1-Ia30.64, which differ from compounds of

Ia1.1-Ia1.64 in that B" means methoxy, K"Z means ethyl and K"" means methyl.

What - I'm full: o

Psa sha VN I'm where. pelvis with ;z" Na ak i li Ve i sn 2 Na shi 18 Yi i - and Nv is I

From a dream

Also preferred are, in particular, compounds IaZ1, especially compounds IaZ31.1-Ia31.64, which differ from compounds Ia1.1-Ia1.64 in that B" means methoxy, B"Z means isopropyl and B"" means methyl . 7 and same V sh Sha vno tazi vo i Mei vOvsnu

Also desirable are, in particular, compounds Ia32, especially compounds Ia32.1-Ia32.64, which differ from compounds in; 1а1.1-1а1.64 because VK! means methoxy, KZ means tert-butyl and K"" means methyl.

td seym y 7. vo shi she shi iz Also desirable are, in particular, compounds IaZ33, especially compounds Ia33.1-Ia33.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl. and zu. In and see and WE in: roya BOS r shchi | (Se)

On (about)

Also desirable are, in particular, compounds Ia34, especially compounds Ia34.1-Ia34 64, which differ from compounds av

Ia1.1-Ia1.64 by what B? means ethylsulfonyl and КВ"Z means ethyl. so ii o: louse ЗНе side c. Blue (e)) (ав) Also desirable are, in particular, compounds Ia35, especially compounds Ia35.1-Ia35.64, which differ from compounds of 070. a1.1-a1.64 in that B" means ethylsulfonyl and KZ means ethyl.

VO alone 55 . tsy de y n sho 7 Y. HE AND OZONE

СВИСН3312 b Also desirable are, in particular, compounds IaZb, especially compounds IaZ36.1-Ia36.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl and BZ means tert-butyl. i pedsha u i s ody

SASNe ra.

Also desirable are, in particular, compounds Ia37, especially compounds Ia37.1-Ia37.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl and K"" means methyl. Dir. ney "u. punk I M. shk sia es still | Her. | d z» odi MV I y ho tazzh o

AND HE 5bhsoN. F (av)

Also desirable E are, in particular, compounds IaZ38, especially compounds IaZ38.1-Ia38.64, which differ from He compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, BZ means ethyl and B" means methyl. 35 . shk her : zho Z « same a. . son Ne ov 2 ih She kis nyny be, : do not sew nits: Z - I vro i (av) Also preferred are, in particular, compounds Ia39, especially compounds Ia39.1-Ia39.64, which differ from compounds 070.a1.1-1a1.64 in that B? means ethylsulfonyl, K means isopropyl and K"" means methyl.

Ф My zy to yu pav YAN SHT ai ta39

V. y y y chi vi pil what m m y Re, i. y y o 60 y y SCHE BE zh Sha tky Ki y dosch 65 Also desirable are, in particular, compounds Ia40, especially compounds Ia40.1-Ia40.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, KZ means tert-butyl and K" means methyl.

What else are you doing?

Shle and shishe V M ta4b sisni) with

Also desirable are, in particular, compounds Ia41, especially compounds Ia41.1-Ia41.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl and 2 means ethylsulfonyl. ab i | yah Ya ya : ryh ya Ya E i -Y. - Y E p. with:

TITTdln their Fu

Also desirable E, in particular, compounds Ia42, especially compounds Ia42.1-Ia42.64, which differ from compounds o

Ia1.1-Ia1.64 by the fact that B" means methyl, B? means ethylsulfonyl and КВ "З means ethyl. (Se) se i- s p pona i i pok ots o S 5 ee z KE « y Y on MBO Ne -i . University of Ge

Ф SenЕ o Also desirable are, in particular, compounds Ia43, especially compounds Ia43.1-Ia43.64, which differ from compounds со 50 а1.1-(а1.64 in that B! means methyl, B? means ethylsulfonyl, and BZ means isopropyl

Also desirable are, in particular, compounds Ia44, especially compounds Ia44.1-Ia44.64, which differ from compounds 65 Ia1.1-Ia1.64 in that EK! means methyl, K2 means ethylsulfonyl and K"Z means tert-butyl.

I'm sleeping in a yak; still sha in . | and in E, however, about | and be from NYA I rise

Also desirable are, in particular, compounds Ia45, especially compounds Ia45.1-Ia45.64, which differ from compounds 79 |a1,1-Ia1.64 in that B | EC" means methyl and B"Z means ethylsulfonyl. " what. in I we YAN Ye her dae ME o Ki Iva. 7 še KOasSane

Also desirable are, in particular, compounds Ia4b6, especially compounds Ia46.1-Ia46.64, which differ from compounds Fo

Ia1.1-Ia1.64 by the fact that B! | K"" mean methyl, B? means ethylsulfonyl and B C means ethyl. o v ye a s, y y y (So) ve. With Ya and Ka; SHE s i and -

Mezhria Shk siza IY still o) s y i sha g "Tl TI. sht nich tak pa. " td yo i t

Exactly -I

Also desirable are, in particular, compounds Ia47, especially compounds Ia47.1-Ia47 64, which differ from compounds b Ia1.1-Ia1.64 in that B" and B"? means methyl, K2 means ethylsulfonyl and means isopropyl.

Fo o b dyn

ТП ст терки Но я Е т ст ,: ее ст ; : 7 o pra y z zhe shi ШЧ no ро BO Szne: vo SNiSNz z

Also desirable are, in particular, compounds Ia48, especially compounds Ia48.1-Ia48.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B and B"" mean methyl, B? means ethylsulfonyl and BZ means tert-butyl. b5

; VOSYAu is a miracle and we are Tazhy 70 Mk | and pf p. you are not

STSNIZ: 75 dust

Also desirable are, in particular, compounds Ia49, especially compounds Ia49.1-Ia49 64, which differ from compounds

Ia1.1-Ia1.64 in that B" means trifluoromethyl and B" means ethylsulfonyl.

Still SE m och SHI;

Her and her, 7,. I . ne - -- dk ke ayy Bon v y ; For. schi a DYN zo o ro GOD.

SI. F

Also desirable are, in particular, compounds Ia5O, especially compounds IabBoO.1-Ia50.64, which differ from compounds o

Ia1.1-Ia1.64 in that B" means trifluoromethyl, K2 means ethylsulfonyl, and K"Z means ethyl. |se) also Vs Bow M 0 fer ro OV - and I di- N ie NE NK i dru, shk « ! go - TS Z Y tav - » Mody sh that 1 toatht r - SN

F and av | Also desirable are, in particular, compounds Iab51, especially compounds Ia5b1.1-Ia51.64, which differ from compounds 50. Ia1.1-Ia1.64 in that B! means trifluoromethyl, EC? stands for ethylsulfonyl and KZ stands for isopropyl.

F ia r sia V

GF! some ke ZE tya g! 1 Ше з гай К Шо с szhеофнний бо и шН ВО Ne syst: бо Also desirable are, in particular, compounds Ia52, especially compounds Ia5b52.1-Ia52.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means trifluoromethyl, B? means ethylsulfonyl and BZ means tert-butyl. z o ska ay t--- Xia STILL Alive.

DE s sao MOSCHI in u i BOZZONE oh

SS

Also desirable are, in particular, compounds Ia53, especially compounds Ia53.1-Ia53.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means trifluoromethyl, K2 means ethylsulfonyl and B"" means methyl. » same OB

Ve and ; , it "hin and la pa E E nina ; i mya so i he BOZZSNe 4 ich1xE 7 sho o zo SNU b"

Also desirable are, in particular, compounds Iab54, especially compounds Iab4.1-Ia54.64, which differ from compounds o

Ia1.1-Ia1.64 by the fact that B" means trifluoromethyl, K2 means ethylsulfonyl, B"Z means ethyl and B" means methyl.

ОО 00 бЭх дибки ож. lai te che Sche nn «6 doty ts and genes FOAM eh v aa. and with with : ; and And d. What And and ; :» Mei kdd shi yin "v Z r Shef Neva z Ka 18 1 EE Osn and SUK. o Also desirable are, in particular, compounds Ia55, especially compounds Iab55.1-Ia55.64, which differ from compounds

Ta1.1-Ia1.64 by the fact that KE" means trifluoromethyl, KE? means ethylsulfonyl, KZ means isopropyl and BK"? means (Ce) methyl.

F g. sa:

PC in the 1st M p IN - own fi: ze and (F) yo spla OS dya "SHIE iy p DB theo bo tt EN z gai TO Yake dr or schu bo Also desirable are, in particular, compounds Ia5b, especially compounds Iab5b .1-Ia56.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means trifluoromethyl, K7 means ethylsulfonyl, B" means tert-butyl and K"" means

ОБЖ жек п Jak shchey tyl V I "Not where I am; ; - re in. SHA with in. Ч ч и У к з и И о и: I hai

Senya

Also desirable are, in particular, compounds Ia57, especially compounds Ia57.1-Ia57.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methoxy and KE? means ethylsulfonyl.

CHE SYH nev siv ge ZHE 2 sr and shchi and yah. from K, sha. Jan "o: Shk: fairy

Phi sch i o Ky Taschu sch

Nya, in . zh: rya ali le SCHE: ii. zon, y y i tea ve Ge) - oh and; : s y n BRA V . she and ro BbisyaN. I di Y x,

SNU F

Also desirable are, in particular, compounds Ia58, especially compounds Iab58.1-Ia58.64, which differ from compounds (a)

Ia1.1-Ia1.64 by the fact that B! means methoxy, VE? means ethylsulfonyl and BZ means ethyl. so od be sshkh is EXTERNAL; Sha (I I what.

ZE: p shi. 1 slorni de m y y t t Vito b: zh shu et " to her I; y I I Щ TE z taya: p "» r h ee o, art. ii nk p

Sen. x -I - b Also desirable E are, in particular, compounds Ia59, especially compounds Ia59.1-Ia59.64, which differ from compounds o Ia1.1-Ia1.64 in that B" means methoxy, K2 means ethylsulfonyl and BZ means isopropyl. us. and: ! this

Zh. Syu: Sweaters: lyky o kove My lk WRITE and in tor Osn in Y. Mon, I I shi

Also desirable are, in particular, compounds Iabo, especially compounds Iabo.1-IaboO.64, which differ from compounds

Ia1.1-(a1.64 by the fact that EC! means methoxy, 2 means ethylsulfonyl and B "Z means tert.-butyl.

Also preferred are, in particular, compounds Iab1, especially compounds Iab1.1-Iab1.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methoxy, B? means ethylsulfonyl and B" means methyl. ee mes ! "tv ki Her pini І І ОООЭУ oh Her By. ih still you A і svia grav.

And V. g. and che KE. rei y g ia vi VO. about (Se)

Also desirable are, in particular, compounds Iab2, especially compounds Iab2.1-Iab2.64, which differ from compounds F

Ia1.1-Ia1.64 by the fact that B! means methoxy, VC? means ethylsulfonyl, BZ means ethyl and B" means methyl.

STILL TO ov SHY h -- Tov BezbaNE. Also preferred are, in particular, compounds Iab3, especially compounds Iab3.1-Iab63.64, which differ from compounds

Ge») Ia1.1-Ia1.64 in that B" means methoxy, K2 means ethylsulfonyl, KZ means isopropyl and K"" means methyl.

ДЯ - и '. g. : : : Go E so g. o bnisSku)"

Also desirable are, in particular, compounds Iab4, especially compounds Iab4i.1-Iab4.64, which differ from compounds

Ia1.1--41.64 because K' means methoxy, KB? means ethylsulfonyl, KZ means tert.-butyl and B" means methyl.

And years of wars

Also desirable are, in particular, compounds Iab5, especially compounds Iab5.1-Iab5.64, which differ from compounds Ia1.1-Ia1.64 in that B? means chlorine. b Y5 o M ' i same. . that's why - is)

Also desirable are, in particular, compounds Iabb, especially compounds Iabb.1-Iabb6.64, which differ from compounds F

Ia1.1-Ia1.64 because K? means chlorine and KZ means ethyl. Sh

VO ody F

From t Kk Y - i a os x tabb nn ya Shk y na oh p ah UOmy. F | what

Also preferred are, in particular, compounds Iab7, especially compounds Iab7.1-Iab7.64, which are different from these compounds. Ia1.1-Ia1.64 by what B? means chlorine and K"Z means isopropyl. Sh o nn, Ezai ry a i-y 5 i. (se) J. 1. z I

F sho dn aiv shi lish NI Pe i tab eNisSNTo. for

Also desirable are, in particular, compounds Iab8, especially compounds Iabv.1-Iab8.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine and KZ means tert-butyl. b5 wallpapers; i po ve No I OV chn tav

In and with share: i. What are we for? education" -

Also desirable are, in particular, compounds IabO, especially compounds Iabo.1-Iab9.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine and B"" means methyl. and poison TOU with I I Sho ; - and for I eh ; Bonya their x her o mKya iaB8. I'm still 85

And Ge) I Ge)

Also desirable are, in particular, compounds Ia70, especially compounds Ia70.1-Ia70.64, which differ from compounds |a1,1-i81.64 in that K2 means chlorine, B" means ethyl and K"" means methyl. -

I t y E. t y

К.

F Sun; (av)

Also desirable are, in particular, compounds Ia71, especially compounds Ia71.1-Ia71.64, which differ from compounds i-o Ia1.1-Ia1.64 in that B? means chlorine, KZ means isopropyl and K"" means methyl. 4) 5B ssh, Y t. chi me in 60 Be . how oi her zi i - E V he b - i i

Also desirable are, in particular, compounds Ia72, especially compounds Ia72.1-Ia72.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, VE Z means tert-butyl and B" means methyl

SE rila: SI o. I "y

Also desirable are, in particular, compounds Ia73, especially compounds Ia73.1-Ia73.64, which differ from compounds 20 Ia1.1-Ia1.64 in that B" means methyl and K2 means chlorine. U y t atatz zo y chu TLAJAYE Ne Kei -- (Se)

Her F

Also desirable are, in particular, compounds Ia74, especially compounds Ia74.1-Ia74.64, which differ from compounds (se) with 181.1-181. in that B" means methyl, 2" means chlorine and B C means ethyl. m ee sei Sh y ch y y cy; what

F Song (av)

Also desirable are, in particular, compounds Ia75, especially compounds Ia75.1-Ia75.64, which differ from compounds se) I t 1 2 :p1Z I : a1.1-(a1.64 tim, and "okK" means methyl, K- means chlorine and K 7 means isopropyl.

I : z E E y ZK iya : ts y she Ne: y sn(sniiz i

Also desirable are, in particular, compounds Ia7b6, especially compounds Ia76.1-Ia76.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl, B? means chlorine and B C means tert-butyl. i: g de et I o SN. dyny - What ko Y sm -Z she I he idntrtyns 4 go - 1 I o t t ay y sr pn Sha sho Ж tt Gyah sh KE s sik Y neo I kli She s EE ED i. MK re to | Be with F

Also desirable are, in particular, compounds Ia77, especially compounds Ia77.1-Ia77.64, which differ from compounds -

Ia1.1-Ia1.64 by the fact that B" and B"? mean methyl and B? means chlorine. av, still shk ashoshch so 50 rik

Ф Also desirable are, in particular, compounds Ia78, especially compounds Ia78.1-Ia78.64, which differ from compounds

Ia1.1-Ia1.64 in that B and B"! mean methyl, B? means chlorine and B"Z means ethyl. (F) ko bo b5

About; alone vd m shi she y

THE SAME; I'm still. and yah or and seed of it- This is clear in E borgy nya Я as IN; eh y v still tab t ek : i - as o M de te h Ach "VZ "Sne 15

Also desirable are, in particular, compounds Ia79, especially compounds Ia79.1-Ia79.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! and BM stand for methyl, B2 stands for chlorine and B "Z stands for isopropyl. 20 B ia vok p naya ve. 0000 I A M Nv vot t g zh o Z o pa:

Also desirable are, in particular, compounds Ia0O, especially compounds Ia80.1-Ia80.64, which differ from compounds o

Ia1.1-Ia1.64 by the fact that B! and B" mean methyl, B2 means chlorine and B"Z means tert-butyl. and (Se) and. me . .-. My Nh and I them and 35 du KE in t; yana I koi - i DY KK "DV. sho - Mokry ZSh u v p i. s(bnziz y (СН - Also desirable are, in particular, compounds Ia81, especially compounds Ia81.1-Ia81.64, which differ from compounds

Ge") Ia1.1-Ia1.64 by the fact that V! means trifluoromethyl and B? means chlorine. » booobveodiyoy m, - y "v - M i Rush DATA M tt There are:

K stenvnia San ke v. and about Mer en. p che mia, etc

Also desirable are, in particular, compounds Ia82, especially compounds Ia82.1-Ia82.64, which differ from compounds

Ia1.1-Ia1.b4 by what VE! mean trifluoromethyl, K2? means chlorine and KZ means ethyl. b5

Compounds Ia83, in particular, are also desirable. especially compounds Ia83.1-Ia83.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means trifluoromethyl, B? means chlorine and KZ means isopropyl. p.

WE V

Wasp some: . І І What І з s snia Ks Shiya s: schy y ia sizyl l Yar hi yav ko IZ y. with her miss". KB Shchi 1 C si. about (Se)

Also desirable E, in particular, compounds Ia84, especially compounds Ia84.1-Ia84.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means trifluoromethyl, K2 means chlorine, and KZ means tert-butyl. -

At least and . With o even and -y « rya CHI: NK ns: UAD p. - with I DY and NI in "div. te ON: i.

Also desirable are, in particular, compounds Ia85, especially compounds Ia85.1-Ia85.64, which differ from compounds "so 050. at.1-i81 64 in that B! mean trifluoromethyl, K? means chlorine and VK"! means methyl. из ШЕ шей

ОБ дуе пре І и І І Ш Ш Ш Ш Ш Ш Ш nn, lkve schy p De vo vo E na si oh to ШЧ

CH: 65 Also desirable are, in particular, compounds Ia87, especially compounds Ia87.1-Ia87.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! mean trifluoromethyl, K2 means chlorine, BZ means isopropyl, and "B" means methyl.

There is one more in the crotch

Vr SHI | more b, sl y eh sho B vni y -- wo sce p. pod pe - s nia y UNN Z Shche tyu s o IN era ly: LIV NI

Also desirable are, in particular, compounds Ia88, especially compounds Ia88.1-ia88.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! mean trifluoromethyl, VK? means chlorine, BZ means tert.-butyl, and B? means methyl. as ori her Y , her

SHY you nya and t -ri. - int zi i iya Yara! 7 and; r. | Kk tav se

M. t so dya a v. isenny U y y h cha . F from CISneu i: F (av)

Also desirable are, in particular, compounds Ia89, especially compounds Ia89.1-Ia89.64, which differ from compounds

I 1 :rdo2 (se) a1.1-I(a1.64 by the fact that K' means methoxy and K- means chlorine. 35 . in particular, compounds Ia90, especially compounds Ia900.1-Ia90.64, which differ from compounds (se) Ia1.1-Ia1.64 in that B! means methoxy, B? means chlorine and E"Z means ethyl. also I - no I I yes 500 The sword is flowing and the dog b5 Y

Also desirable are, in particular, compounds Ia91, especially compounds Ia91.1-Ia91.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methoxy, B? means chlorine and B. C means isopropyl.

And 1. | !

Sh b r y vn VV: eozk

EI V yivai,

Fn(Sn3)z

Also desirable are, in particular, compounds Ia92, especially compounds Ia92.1-Ia92.64, which differ from compounds uh Ia1.1-Ia1.64 in that B" means methoxy, VK? means chlorine and B"Z means tert. -butyl. y y es Keh koki t, y s

E Nnskesi sti F sissnuh o (Se)

Also desirable are, in particular, compounds Ia93, especially compounds Ia93.1-Ia93.64, which differ from compounds |a1.1-I841.64 in that B! means methoxy, KE? means chlorine and K"" means methyl. - writes There are also OS j i « che sia, і Што: E і і ос, і сты Z

From E Z KU "VZ sha: Bonn ZINEnk a ch i des! b tiig o. o Snu s 50 Also desirable are, in particular, compounds Ia94, especially compounds Ia9b4.1-Ia94.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methoxy, B? means chlorine, K Z means ethyl and VK" means methyl. ze ! y Te g ' y o : and this sh- M y | she doesn't care. y zh" Sh y a tshi sh'Mi ; sv what: B; this is du still "At Tai te shk nt still put i Not and I frog

Also desirable are, in particular, compounds Ia95, especially compounds Ia95.1-Ia95.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methoxy, B? means chlorine, BZ means isopropyl and B "means methyl. reco "dreadlocks still sleeping MN Y ro aa. then CHI ---E | y DE mi miy z dya Sh yo sha, You I and I and snesnz o. and

Also desirable are, in particular, compounds Ia9b6, especially compounds Ia9b.1-Ia96.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methoxy, K2 means chlorine, VK "Z means tert-butyl and K" means methyl.

Ki - day. 0 sh Os deya her not. DI! V : : A. bird and I psa sta s 7 І ІІ. 7 And hey and taz o

It dawns and GE sh te cha ; en, - gi ne yi Shk What and what ; MELONS F o.on. at

Also desirable are, in particular, compounds Ia97, especially compounds Ia97.1-Ia97.64, which differ from compounds (se)

Ia1.1-Ia1.64 by what B? means trifluoromethyl. they are 20 years old; : And with

She a m a loh She

F SYA

(ав) со 20 Also desirable are, in particular, compounds Ia98, especially compounds Ia98.1-Ia98.64, which differ from compounds

Ф Ia1.1-Ia1.64 by what B? means trifluoromethyl and KZ means ethyl. (F) ko bo b5

I am - But that's still V

And and | ni cha g: Z . and neither: whatever. re le di m co

Also desirable are, in particular, compounds Ia99, especially compounds Ia99.1-Ia99.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means trifluoromethyl and KZ means ethyl. with re k ni s aa same in Z (av)

Also desirable are, in particular, compounds Ia100, especially compounds Ia100.1-Ia100.64, which differ from compounds He)

Ia1.1-Ia164 by what KV? means trifluoromethyl and BZ means tert-butyl. m tk z-d sha ny sce I sh shi "v he V "I, .. TE " ih sii that: Sh

And the SCC

F SSP: I o Also desirable are, in particular, compounds Ia101, especially compounds Ia101.1-(a101.64), which differ from compounds "co 050. |a1.1-i81.64 in that B? means trifluoromethyl and K "7 means methyl.

OO yu pok 7 fa... and I would like to ski: pcs. ш 60 Y On What "EEC e

Also desirable are, in particular, compounds Ia102, especially compounds Ia102.1-Ia102.64, which differ from compounds dv; 181.1-1a1.64 in that 2 means trifluoromethyl, B "Z means ethyl and B" means methyl.

not zhk V t, Che iy z ku shu ; yah and her ha and za and -2 horror 70 ki ti; | I. sleep re

Sun and YAN

Also desirable are, in particular, compounds Ia103, especially compounds Ia103.1-Ia103.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means trifluoromethyl, В Z means isopropyl, and B" means methyl. sh- what I ne y and Fo Y i o shi i nai what Sh ich Hai vn y x "V de gde schi y Keti Se z" UN(SNZI z. F (av)

Also desirable are, in particular, compounds Ia104, especially compounds Ia104.1-Ia104.64, which differ from compounds "with

Ia1.1-Ia1.64 by what B? means trifluoromethyl, B C means tert-butyl and B" means methyl. k

Both wild povi iya | M y She - s se. sh more ich more shk. Mk about her. Sintai is "Vb tob a tie

Med Z She -a 72 o syh m

20 Also desirable are, in particular, compounds Ia105, especially compounds Ia105.1-Ia105.64, which differ from compounds

F Ia1.1-Ia1.64 by the fact that B! means methyl and 2? means trifluoromethyl.

GF! Hey: t y write she Ж жаио5 bo Fev oh, I b5 KN:

Also desirable are, in particular, compounds Ia106, especially compounds Ia106.1-Ia10664, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means methyl, B" means trifluoromethyl, and KZ means ethyl.

Also desirable are, in particular, compounds Ia107, especially compounds Ia107.1-Ia107.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl, B? means trifluoromethyl and B"Z means isopropyl.

Also desirable are, in particular, compounds Ia108, especially compounds Ia108.1-Ia108.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means methyl, B? means trifluoromethyl and KZ means o

VE in і- і ve ak: "MM tashov. with with with, | I | "re sov se, don Ya rrtei VI DK Ya

V. Sen o Also desirable are, in particular, compounds Ia109, especially compounds Ia109.1-Ia109.64, which differ from compounds Ia1.1-Ia1.64 in that B" and B"? mean methyl and B? means trifluoromethyl.

F ok zro

Io) ke І GAY І --- not 60 1 | HE her Eh.

Sleep

Also desirable are, in particular, compounds Ia110, especially compounds Ia110.1-Ia1 10.64, which differ from compounds |a1.1-Ia1.64 in that KE and 27" mean methyl, K2 means trifluoromethyl and KE "Z means ethyl .

b sv y I sn y TE | ИЙ yo; Co. and 119. 76 in | вк, Ya ze NA" ria Still g yah z

Sen;

Also desirable are, in particular, compounds Ia111, especially compounds Ia111.1-(a111.64), which differ from compounds

Ia1.1-Ia1.64 by the fact that B and B"" mean methyl, B? means trifluoromethyl and BZ means isopropyl. s: zn I shchi ploti neya i rn -

A re, Z hi . "at la -t and a Be - v and I and sya ; shcha te and K. and Z: ta111. s 2 her | ve o

Already -y o "y Yake and Ve zhh NO and to SE " from sn(snoY o. b

Also desirable are, in particular, compounds Ia112, especially compounds Ia112.1-Ia112.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? means methyl, K2 means trifluoromethyl and K C means tert-butyl. o o o ar HOW o o ' S disc as i-

Don't have dreams

SISNU) with -i and

Also desirable are, in particular, compounds Ia113, especially compounds Ia113.1-Ia113.64, which differ from compounds (22) | 1;p2 a1.1-I(a1.64 in that K' and K- mean trifluoromethyl. (ав)

F she shk and vo | you, I: y.

Also desirable are, in particular, compounds Ia114, especially compounds Ia114.1-Ia114.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that ВЕ" and В? mean trifluoromethyl and VK З means ethyl.

Also desirable are, in particular, compounds Ia115, especially compounds Ia115.1-Ia115.64, which differ from compounds

Ia1.1-Ia1.64 in that B" and B? mean trifluoromethyl and B "Z means isopropyl. shchi eh vo ps do

No, I'm still standing. lines as well as But and p2 pe B,

BACKGROUND

Also desirable are, in particular, compounds Ia116, especially compounds Ia116.1-Ia116.64, which differ from compounds ee, za1,1-I81.64 in that B and B? means trifluoromethyl and B C means tert-butyl. F what what AI g | Z y 2 yt- po shchy y B taiib: ney Or: t. I y "z I ; no SC -| Also desirable are, in particular, compounds Ia117, especially compounds Ia117.1-Ia117.64, which differ from compounds b Ia1.1-Ia1.64 by the fact that B" and B? mean trifluoromethyl and "B" means methyl.

Also desirable are, in particular, compounds Ia118, especially compounds Ia118.1-Ia118.64, which differ from compounds Ia1.1-Ia1.64 in that B and B? means trifluoromethyl and B" means methyl.

osv dyn o Z I "de ; svv What I IY n vyh I o Dy Sho and Y i vaika ka

Also desirable E, in particular, compounds Ia119, especially compounds Ia119.1-Ia119.64, which differ from compounds

Ia1.1-Ia1.64 by what B and B? mean trifluoromethyl, B means isopropyl and B means methyl.

Zh F

Also desirable are, in particular, compounds Ia120, especially compounds Ia120.1-Ia120.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B" mean trifluoromethyl, EK Z means tert.-butyl and K"" means methyl. with som Z shchi Z

CH) -1 Also desirable are, in particular, compounds Ia121, especially compounds Ia121.1-I(a121.64, which differ from compounds about Ia1.1-Ia1.64 in that B! means methoxy and B? means trifluoromethyl. o e: Osn niya that o Yaka Ei nei 4") and that and o. - Well, I'm sweaty. she yu I. with bo

Also desirable are, in particular, compounds Ia122, especially compounds Ia122.1-Ia122.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methoxy, B? means trifluoromethyl and B C means ethyl. b5 that vein MOV 000 Obneuyetnyah

IN; eat 1.00 a.m. not

In v ns Y Where t?

THAT is the TV of the 70s; SE

Also desirable are, in particular, compounds Ia123, especially compounds Ia123.1-Ia123.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methoxy, K2 means trifluoromethyl and VK"Z means isopropyl. r 1 t chi 15 y t. t I t Ne seti

He and her iy t V hai23

Meme oh shi oh

Also desirable are, in particular, compounds Ia124, especially compounds Ia124.1-Ia124.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methoxy, K2 means trifluoromethyl and B"Z means tert-butyl. at 3: SN. si - y shi: Shi: eh? KSNi)z b Also desirable are, in particular, compounds Ia125, especially compounds Ia125.1-Ia125.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methoxy, K2 means trifluoromethyl and VK "" means methyl. (av) w y. 4» Kk I pi z sne and Kyy shk sv 60 century g.

Also preferred are, in particular, compounds Ia126, especially compounds Ia126.1-Ia126.64, which differ from compounds where Ia1.1-Ia1.64 in that B" means methoxy, K2 means trifluoromethyl, K C means ethyl and K" " stands for methyl.

and in my wife I give TO Both

Щ What z v nya, y, sya sya ve y kh he i s t i: what zi ladan ti -Y TI Y ee; ov: taiyYe to ek yk, Ka y y on pas. Sho and 12 Also desirable are, in particular, compounds Ia127, especially compounds Ia127.1-Ia127 64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methoxy, B? means trifluoromethyl, B"C means isopropyl and B" means methyl.

In 0 beans de iy " ve Esh she;

I You he yT820t a nya Ks y t Y SHU She rhy s

Also desirable are, in particular, compounds Ia128, especially compounds Ia128.1-Ia128.64, which differ from He compounds)

Ia1.1-Ia1.64 by the fact that B" means methoxy, K2 means trifluoromethyl, KE "Z means tert.-butyl and EK" means methyl. o 0 fill in Ф

NO. but also 2 and 4 and oi - also s» nyan ne svi boyav te and o sa CHI ke Z p C. Y I z» pe do - 45 Also desirable are, in particular, compounds Ia129, especially compounds Ia129.1-Ia129 .64, which differ from compounds

Ia1.1-Ia1.64 by the fact that VZ means chlorine. so CT : ; from San

Ks WE: Yi She ay i gi khata a 1| Sho. ve o I Ok 05SNU

Siz Si. because J

Also desirable are, in particular, compounds Ia130, especially compounds Ia130.1-Ia130.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that BZ means chlorine and K"Z means ethyl. b5 sh tk В бобы " sew VA iai3o ze su y m kva yi Z y sv YAN t Also desirable are, in particular, compounds Ia131, especially compounds Ia131.1-Ia131.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that VZ means chlorine and K"Z means isopropyl.

And about odyssey

Also desirable are, in particular, compounds Ia132, especially compounds Ia132.1-Ia132.64, which differ from compounds Ia

Ia1.1-Ia1.64 by the fact that VZ means chlorine and KZ means tert.-butyl. aw! tsy Eh what what - g Sh nik y ke Ya. х ше ч- - Vely and I g» Ton dobet

In sy: (SN. Z Sh: -I KI Em

Ge) Also desirable are, in particular, compounds Ia133, especially compounds Ia133.1-Ia133.64, which differ from compounds about Ia1.1-Ia1.64 in that BZ means chlorine and B"" means methyl. o pnia z DE zvshi SHY av s anna zayi35 vo i I "LA, | ! Byka Y si dv,

Also desirable are, in particular, compounds Ia134, especially compounds Ia134.1-Ia134.64, which differ from compounds dio/181.11181.64 in that BZ means chlorine, VE C means ethyl and B" means methyl.

o s 7 nya i shcha her | he sozsv dream, p

Also preferred are, in particular, compounds Ia135, especially compounds Ia135.1-Ia135.64, which differ from compounds 75. Ia1.1-Ia1.64 in that BZ means chlorine, KZ means isopropyl and K"" means methyl. -k ay kv lish BUT WE are on teai55

And HER where: with | he | Hobevu sch t p Ge | - - Gee)

Also desirable E are, in particular, compounds Ia136, especially compounds Ia136.1-Ia136.64, which differ from compounds Hezo a1.1-Ia1.64 in that KZ means chlorine, KZ means tert-butyl and KE" means methyl. Ф all Ж Do y -eov yiv136 pli yan Shk zda: "

As 7th: not and with ZON: - p g and tar KV dk (6 g» bisnuuh

Also desirable are, in particular, compounds Ia137, especially compounds Ia137.1-Ia137.64, which differ from compounds Ia1.1-Ia1.64 in that B! stands for methyl and EZ stands for chlorine. (is))

Zk: yes, M.O. THE SAME

I«e) Zh t ih 1, I - Vel pl ve

F z: Na yaz I Ya sa;

Also desirable are, in particular, compounds Ia138, especially compounds Ia138.1-Ia138.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means methyl, BZ means chlorine and VK Z means ethyl. b5 and Km and tone To BOEV

Also desirable are, in particular, compounds Ia139, especially compounds Ia139.1-Ia139.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! stands for methyl, BZ stands for chlorine and BZ stands for isopropyl. in She

A dn or nn: VV taIz9 sch sv M shk CHYNY gy vozSnu F 5. mu nya CHA r I schy it as IN her Me)

Also desirable are, in particular, compounds Ia140, especially compounds Ia140.1-Ia140 64, which differ from compounds He) with Ia1.1-Ia1 64 in that B! means methyl, BZ means chlorine and BZ means tert-butyl. cha yo VZ in m "

CY 1 kN sh s Y sok zv sive - ": chi - s lsh Sun 47 and shi no

F Sibnews (av)

Also desirable are, in particular, compounds Ia141, especially compounds Ia141.1-I(a141.64, which differ from compounds Ia1.1-Ia1.64 in that KE" and B" mean methyl and BZ means chlorine. o t a sny v toi 60 t Mshe a cha 7 Olya, uv o. 65 Also desirable are, in particular, compounds Ia142, especially compounds Ia142.1-Ia142.64, which differ from compounds

Ia1.1-Ia1.64 in that B and B"" mean methyl, BZ means chlorine and BZ means ethyl. o What o; Si Nai to and el

Also desirable are, in particular, compounds Ia143, especially compounds Ia143.1-Ia143.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? stand for methyl, KZ for chlorine and KZ for isopropyl. ss October oo oz pd py shi shi. YV

I had her on August 7. from sleep with F

Also desirable are, in particular, compounds Ia144, especially compounds Ia144.1-Ia44.64, which differ from compounds o

Ia1.1-Ia1.64 by the fact that B" and B"? means methyl, KZ means chlorine and KZ means tert-butyl. ise) dev ge -

Fon o de ni i ori y en zatva s I iy she dv; she and

MeKTYA chu tv p, sv x, t Ii (e))

Also desirable are, in particular, compounds Ia145, especially compounds Ia145.1-Ia145.64, which differ from compounds Ia1.1-Ia1.64 in that B? means ethylsulfonyl and EZ means chlorine. i'm going

WHETHER I AM. and and Sh nya bla tsi se "in . pt UZH s t, I -- 5; and Shan des l-re in vo Yi on and ZO5SENE.

KV; h 65 Also desirable are, in particular, compounds Ia146, especially compounds Ia146.1-Ia146.64, which differ from compounds

Ia1.1-Ia1.64 by what B? stands for ethylsulfonyl, WZ stands for chlorine and WZ stands for ethyl.

pi pl Ese DY 0 Mee E i Z i sht i- i ttEin z s, it i o

Also desirable are, in particular, compounds Ia147, especially compounds Ia147.1-Ia147.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, KZ means chlorine and KZ means isopropyl. 7 Os de a and Y G . I heard it: I still have the House of the United Nations

R and we F (av)

Also desirable are, in particular, compounds Ia148, especially compounds Ia148.1-Ia148.64, which differ from compounds "with

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, BZ means chlorine and BZ means tert-butyl. k ih y - Still Sh « du still still Sh zay y nys -- KO shlya shk Z zh pod shchi t, y ni i pod. and I and sei ke su shchi E shchi Y - y 7 Y m | 50; Not (ав) Also desirable are, in particular, compounds Ia149, especially compounds Ia149.1-Ia149.64, which differ from compounds 050. а1.171121.64 in that B? means ethylsulfonyl, BZ means chlorine and B" means methyl.

That. With co | Hey and. Zh. - With sake More s; - o 6o t i vi IY "Osn

Also desirable are, in particular, compounds Ia150, especially compounds Ia150.1-Ia150.64, which differ from compounds 65 1a1.1-Ia1.64 in that КВ? means ethylsulfonyl, BZ means chlorine, KZ means ethyl and EC" means methyl. -BO0-

and U nn I vyv, » and en

CH 1

Also desirable are, in particular, compounds Ia151, especially compounds Ia151.1-Ia151.64, which differ from compounds 79 zatlla1.64 in that B? means ethylsulfonyl, BZ means chlorine, BZ means isopropyl and B" means methyl.

SN S. (Se)

Also desirable are, in particular, compounds Ia152, especially compounds Ia152.1-Ia152.64, which differ from compounds (o)

Ia1.1-Ia1.64 because K? means ethylsulfonyl, KZ means chlorine, K "Z means tert.-butyl and K"" means methyl.

Cina -I Also desirable are, in particular, compounds Ia153, especially compounds Ia153.1-Ia153.64, which differ from compounds

F Ia1.1-Ia1.64 by the fact that B" means methyl and EZ means chlorine. z: ZLI g pe z -

F o Ob vy

F; y Z g sha z. and we drank Not I and Z tai53

I'm sorry

Ge) Me and dan y o Neonnia with m I Id bo ON y

Also desirable are, in particular, compounds Ia154, especially compounds Ia154.1-Ia154.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl, B? stands for ethylsulfonyl, BZ stands for chlorine and B "Z stands for ethyl. b5 I still do

U y I 70 Shen ya nenya, nvete iz che i Ya s hd What 1 chn. nOzSane; sune ZHE t Also desirable are, in particular, compounds Ia155, especially compounds Ia155.1-Ia155.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, B? means ethylsulfonyl, KZ means chlorine and K"Z means isopropyl. that | I 0 SNa NYA m my own re and g si Ve Yake and I to whom ev shodo sho ok

І я І є є ke U tTa155 sch

Hey Shchy o shk KU o

Also desirable are, in particular, compounds Ia156, especially compounds Ia156.1-Ia156.64, which differ from compounds (22)

Ia1.1-Ia1.64 by the fact that B! means methyl, B? means ethylsulfonyl, VZ means chlorine | VZ stands for tert-butyl. at

I'm Fri! 7 and as ch- write SHE 7 o TATOb « sn j pishSht b v c) I ro BOzKON I i ch. -I Also desirable E, in particular, compounds Ia157, especially compounds Ia157.1-Ia157.64, which differ from compounds about Ia1.1-Ia1.64 in that B" and B"? means methyl, K2 means ethylsulfonyl and KZ means chlorine. that I: to her about: ak ay (se) 20 HANDS Ei Z As. Ker V i ii sh-oh Yi - and cho tat

Honey tk Still her neck in. Kg t. what about OKO bbuyen's ke you g Ne s. k: 60 Also desirable are, in particular, compounds Ia158, especially compounds Ia158.1-Ia158.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? means methyl, K2 means ethylsulfonyl, KZ means chlorine and KZ means ethyl. b5 ip M GA ; yvi5V yah she a 4 " Medic i pn nn i

Sleep is 75 JACK

Also desirable are, in particular, compounds Ia159, especially compounds Ia159.1-Ia159.64, which differ from compounds

Ia1.1-Iiai1.64 in that K' and 2"' mean methyl, KB' means ethylsulfonyl, BZ means chlorine and B"Z means isopropyl. 2 what I -K. and BOTH are working wonders

That | 8th of June

Also desirable are, in particular, compounds Ia160, especially compounds Ia160.1-Ia160.64, which differ from compounds o

Ia1.1-ia1.64 by the fact that K'" and EK"? mean methyl, BC? means ethylsulfonyl, KZ means chlorine and B"Z means "o tert.-butyl. what

F siSnu) s (av)

Also desirable E, in particular, compounds Ia161, especially compounds Ia161.1-Ia161.64, which differ from compounds and Ia1.1-Ia1.64 in that B? and VZ stand for chlorine.

FO tn,

Also ha zYa and. Did NOT have Bieikr, tey and 59 | " y y I S ke y and I; 7 and Kk y r. y 60 Mezhr zh: s k ze , z. YN so Kk t. i y. t / y Sh n Ye: y

SNU with b5 Also desirable are, in particular, compounds Ia162, especially compounds Ia162.1-i2162.64, which differ from compounds

Ia1.1-Ia1.64 by what B? and BZ stands for chlorine and BZ stands for ethyl. ; from ShK vy

Or Vic 70 is in | and. and in Q 35:

Shen KOZH

I'm Kony from

Also desirable are, in particular, compounds Ia163, especially compounds Ia163.1-Ia163.64, which differ from compounds

Ia1.1-Ia1.64 by what B? and BZ stand for chlorine and K "Z stands for isopropyl.

IN

OO dy z ro i eV 158 o

Also desirable are, in particular, compounds Ia164, especially compounds Ia164.1-Ia164.64, which differ from compounds (Ce)

Ia1.1-Ia1.64 in that B2 and BZ mean chlorine and KZ means tert.-butyl. shchi - - "and I Am! and "s p she she chav z" Morrnya chi kh chi - and shchi Kk. And oh! Also desirable are, in particular, compounds Ia165, especially compounds Ia165.1-Ia165.64, which differ from compounds sg Ia1.1-Ia1.64 in that B? and BZ are chlorine and B "7" is methyl.

F OO di V nn v s tated about SHSHSH. and Ha. nya or y g; Na y t - tia Ya bo Y I DE : Kok

Also desirable are, in particular, compounds Ia166, especially compounds Ia166.1-Ia166.64, which differ from compounds

Ia1.1-Ia1.64 by what B? and BZ stand for chlorine, KE "Z stands for ethyl and KV" stands for methyl. b5 -B4-

Fr. sdrg ry M. pozorzhi ki

SHO od shchih la. zhi 1 and Y 7 KE Y shchi o pas Na pn Taiiv8. "SU shcha

Also desirable are, in particular, compounds Ia167, especially compounds Ia167.1-Ia167.64, which differ from compounds

Ia1.1-Ia1.64 by what B? and VZ mean chlorine, K "Z means isopropyl and KE"? means methyl. about WE in | es o | with. shchi sne ay What oh she and I tat

Tk KO ke sch ve V zv. p

SNisneyu Si. F

Also desirable are, in particular, compounds Ia168, especially compounds Ia168.1-Ia168.64, which differ from compounds He)

Ia1.1-Ia1.64 by what B? and BZ mean chlorine, VE Z means tert.-butyl and B" means methyl. o i tt same F

AN nn iviyei s M "o ; ze - i koh 18 : p i Also desirable are, in particular, compounds Ia169, especially compounds Ia169.1-Ia169.64, which differ from compounds b Ia1.1-Ia1.64 in that B1 is methyl and 22 and EZ are chlorine.

Ф жу ды 4) и - : | g TtyU s oh

E І n sok 7 І t Г жан і7- I tv pe DE and the same I

Also desirable are, in particular, compounds Ia170, especially compounds Ia170.1-Ia170 64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl, B? and EZ are chlorine and B C is ethyl. b5 then WE are on our neck vry nya V jala she I | and TA z - 0 M edge y; I'm sorry, what are you doing?

Sun Si

Also desirable are, in particular, compounds Ia171, especially compounds Ia171.1-Ia71.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, B and BZ mean chlorine and K "Z means isopropyl. vaye she and Y sy. | in the hair dryer outside VV tagl ek Shh zo and ze what. b

Also desirable are, in particular, compounds Ia172, especially compounds Ia172.1-Ia172.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, B? and BZ mean chlorine and K "Z means tert.-butyl. about (Se)

SHO nn tai79

I g: ; is. i sia m zhk nn y 5 -v - i. І PO «In the same direct mail. "L - SSnUuz p. (e)) o Also desirable are, in particular, compounds Ia173, especially compounds Ia173.1-Ia173.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! and B"" represent methyl, B2 and BZ represent chlorine. o 50 o VO oi tiv tattz y M I Her i t tssh van "YY dn, y.

Also desirable are, in particular, compounds Ia174, especially compounds Ia174.1-Ia174.64, which differ from compounds -58b-

Ia1.1-Ia1.64 in that B and B"" mean methyl, B and BZ mean chlorine and BZ mean ethyl. I live at "Ek. PY r p et I ni bo zh t ten 7 " y lo y : і- і

Olt v 7 Tek i ve o de How ho lo

Also desirable are, in particular, compounds Ia175, especially compounds Ia175.1-Ia175.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! and B"" are methyl, B2 and BZ are chlorine and BZ is isopropyl. in shchi U Ka

Sh - "were p. zach ЧО жо и что OT оче еще в ое ее WHOSE WE sov.

Zh. s? i sch. che that r. I t I Be 7 uprchen

Also desirable are, in particular, compounds Ia176, especially compounds Ia176.1-Ia176.64, which differ from He compounds

Ia1.1-Ia1.64 by the fact that B and B"" mean methyl, K2 and BE? means chlorine and VZ means tert-butyl. scha od "DE : i ke i y : shiy, this is also s M eV a sii in tai 76 :" KASHA CHO i "ve:

In OV: g and ey - Yi tire

F Sesnzuz o 50 Also desirable are, in particular, compounds Ia177, especially compounds Ia177.1-Ia177.64, which differ from compounds Ia1.1-Ia1.64 in that VE! stands for chlorine and EZ stands for methyl. In particular, compounds Ia178, especially compounds Ia178.1-Ia178.64, which differ from compounds

Ia11-Ia1.64 in that BZ means methyl and KZ means ethyl.

the same the same V

SNM vn Thaitv niks WE I

Plague with more

Also desirable are, in particular, compounds Ia179, especially compounds Ia179.1-Ia179.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that BZ means methyl and KE "Z means isopropyl. ож 0 В -:. . 1; - ше х шовавесд ню » р ОН, BOЗSN; Ф

SN(SNnIe OKU. F

Also desirable are, in particular, compounds Ia180, especially compounds Ia180.1-I(a180.64, which differ from compounds at "" means tert-butyl

Jacques is not what she is, what is she, what is she? cry k. about SDENzZI i ST. Also desirable are, in particular, compounds Ia181, especially compounds Ia181.1-Ia181.64, which differ from compounds 42) Ia1.1-Ia1.64 in that BZ means methyl and B"7 means methyl. that m A ee See si a pa yu Nb Ya a i ah shshch! Her : Kk what Also desirable are, in particular, compounds Ia182, especially compounds Ia182.1-Ia182.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that BZ means methyl, B Z means ethyl and B" means methyl. y y Y gives 3 What V y "NI anna: so i ШЙ nn viv ro ono -5o5s,

Also desirable are, in particular, compounds Ia183, especially compounds Ia183.1-Ia183.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that BZ means methyl, B Z means isopropyl and B" means methyl.

NS not; OD Shchy in yaai85.

SHI And in VN shcha i chen Zh t y ry RY Ge

TV of Bosnia shnIENZIz SN

Also desirable E, in particular, compounds Ia185, especially compounds Ia185.1-Ia185.64, which differ from compounds b

Ia1.1-Ia1.64 in that KE" and BZ mean methyl.

Shchi Y ssh - zha («e) o in one

L izh io shchi i- v che shin Ta185 din i av « v, Y EN | y z s M "ya va v stik, v: tsi V sho --0 zi What p. NYA 7 Also desirable are, in particular, compounds Ia186, especially compounds Ia186.1-Ia186.64, which differ from compounds

Ge) Ia1.1-Ia1.64 by the fact that B! and BZ are methyl and BZ are ethyl. ze | links K. M. on v

Ф and І What kind of person are you sitting in? и и е І | Y s: I x v yu Y on. BOZSN, in SeNe SN:

Also desirable E, in particular, compounds Ia187, especially compounds Ia187.1-Ia187.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! and BZ are methyl and BZ are isopropyl. b5 shchi I I shk o: shNiSNUha ON; And so

Also desirable are, in particular, compounds Ia188, especially compounds Ia188.1-Ia188.64, which differ from compounds

Ia1.1-Ia1.64 in that B and BZ mean methyl and BZ means tert.-butyl. y m an laye o

I. And in

Kerr Jak p: po kry 7 chi ry Shchi ise) z she she F burned uzi z a STE, I shh ("in sSisnumya sv y

Also desirable are, in particular, compounds Ia189, especially compounds Ia 89.1-Ia189.64, which differ from compounds Ia1.1-Ia1.64 in that B", BZ and 2" mean methyl. gi with; "ex. m and 44 tv zzhzh shk JAN. d; Shchyi pi z shchy r intlyav 7 sh A Ko ai ris - Zhe no z iya yet not; g me EK Vk

And av | pe . GE p. a: so 20 - I z

Ф Also desirable are, in particular, compounds Ia190, especially compounds Ia190.1-Ia190.64, which differ from compounds

Ia1.1-Ia1.64 in that B", BZ and B" mean methyl and KZ means ethyl. (F) ko bo b5 ot SHHA more and : ЗШ | I t ss naE Jov ai en. dad is Me s sna CHASHI

Sleep; CH t Also desirable are, in particular, compounds Ia191, especially compounds Ia191.1-I(a191.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B", VZ | "E mean methyl and KE "Z means isopropyl. o OH; 7 Bez na oo y ten in BB tat91 shi she zhNesSn; sne F rea - pl o

Also desirable are, in particular, compounds Ia192, especially compounds Ia192.1-Ia192.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B", BZ | E"" mean methyl and K Z means tert.-butyl. o pnia (Te) pe Shche. s s da ACTS 47 scene" On

FO Also desirable are, in particular, compounds Ia193, especially compounds Ia193.1-Ia193.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl and EZ means methyl. and 50 pcs also OD: and "Z. eat I. Ya svi, y nya vi » SN SE

Also desirable are, in particular, compounds Ia194, especially compounds Ia194.1-Ia194.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, BZ means methyl, and KE "Z means ethyl. b5

E TE TK PI t Also desirable are, in particular, compounds Ia195, especially compounds Ia195.1-Ia195.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, KZ means methyl and KZ means isopropyl. sk sho -dI 2 and: sha and pika niv tha195 i and Sh ne s y y s s 25 va I YAE x What YES o

They are, I am, I am not, I am (Se)

Also desirable are, in particular, compounds Ia196, especially compounds Ia196.1-Ia196.64, which differ from compounds av!

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, BZ means methyl and BZ means tert-butyl. since November shchei and I shchei, shh. z y y: p ny tat96 « and E vy va va Her o zh y CHI | y - iz» de a a E " shi '. y B san ek

It's OK on the side. ziku TO l z. NATIONS ZY o rah, - SYANU syh me) Also desirable are, in particular, compounds Ia197, especially compounds Ia197.1-Ia197.64, which differ from compounds about Ia1.1-Ia1.64 in that B? means ethylsulfonyl, BZ means methyl and B" means methyl. "so 20 then zate

Nab. the rest of TYATYAU in - Yautnya still has us Zag. their tya y t She tm i - och p n- ro Bbon vo y tse, tan. she is a SNz

Also desirable are, in particular, compounds Ia198, especially compounds Ia198.1-Ia198.64, which differ from compounds where Ia1.1-Ia1.64 in that B? means ethylsulfonyl, BZ means methyl, VK Z means ethyl and K"" means methyl.

sei 00 DB OK owl. n

Also desirable are, in particular, compounds Ia199, especially compounds Ia199.1-Ia199.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, KZ means methyl, VC "Z means isopropyl and K"? means methyl. schi o r i and their She:

With | o pu I she NN on I he VV. Hut 99

Fo

Also desirable are, in particular, compounds Ia200, especially compounds Ia200.1-Ia200.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, KZ means methyl, K "Z means tert-butyl and K"" means methyl.

You have a glass of puddne shishshnne pelagov:

She she: NIK is drinking. g A i. Also desirable are, in particular, compounds Ia2.01, especially compounds Ia201.1-(a201.64, which differ from compounds

Ge") Ia1.1-Ia1.64 in that B and BZ mean methyl and 2 means ethylsulfonyl. o and zn. se: ze

The child is there

You are right; zhi She S tah: o t av No Ve yu r sBOzSN, sh che What sleep

Also desirable are, in particular, compounds Ia202, especially compounds Ia202.1-Ia202.64, which differ from compounds

Ia1.1-Ia1.64 in that B" and BZ mean methyl, K2 means ethylsulfonyl and КВ "З means ethyl. b5

VBOObnu di

D I DI. y : y: the same

Mer she ste I o ; y dnk t 70 I gy sya nishnny y twity sn

Also desirable are, in particular, compounds Ia203, especially compounds Ia203.1-Ia203.64, which differ from compounds

Ia1.1-Ia1.64 in that B" and BZ mean methyl, K2 means ethylsulfonyl and B"Z means isopropyl ester

Q: I am

There is a tone called Fr

Also desirable are, in particular, compounds Ia204, especially compounds Ia204.1-Ia204.64, which differ from compounds (22)

Ia1.1-Ia1.64 by the fact that B! and VZ mean methyl, B? means ethylsulfonyl and BZ means tert-butyl. oh ze bu. so Ku km tet i nn NV u « ch EY. Do not beat them

SaSNIi 0 CH 47 "CH3Iz SNU;

Also desirable are, in particular, compounds Ia205, especially compounds Ia205.1-Ia205.64, which differ from compounds about Ia1.1-Ia1.64 in that B", BZ and B"? means methyl and E2 means ethylsulfonyl. were walking o WHAT I A v ke ta KI sv sia i oo I sedk teo po nt i o: SHE Pe bo Kk. th pc t, on Sn

Also preferred are, in particular, compounds Ia206, especially compounds Ia206.1-Ia206.64, which differ from compounds B181.1-181.64 in that B", BZ and" mean methyl, K2 means ethylsulfonyl and KZ means ethyl.

wash

My, Co

It's not what it is

Also desirable are, in particular, compounds Ia207, especially compounds Ia207.1-Ia207.64, which differ from compounds

Ia1.1-Ia1.b4 in that B", BZ and "7" are methyl, B is ethylsulfonyl and BZ is isopropyl.

PI: food I i h Z i: ni i still. about ON; more She; M g

I am angry with her. and "vv Kk "V aus so nav Ne sv YN o shin ny

SN(ENIIYA SN. o

Also desirable are, in particular, compounds Ia208, especially compounds Ia208.1-Ia208.64, which differ from compounds o

Ia1.1-Ia1.64 by the fact that B", BZ | "E mean methyl, K2 means ethylsulfonyl and B "Z means tert.-butyl.

FO ryu y

Wb I shchi ni shi

Mk p y r her zhi v is shi - and I soni BO Na p dya: kiz she Y K ssh, Nu ' u z. Also desirable are, in particular, compounds Ia209, especially compounds Ia209.1-Ia209.64, which differ from compounds (2) Ia1.1-Ia1.64 in that B? means chlorine and VZ means methyl. o "eh tv. shk i s. y I-ba zn nn U UNN vo a shrey pe

Also desirable are, in particular, compounds Ia210, especially compounds Ia210.1-Ia210.64, which differ from compounds

Ia1.1-Ia1.64 by what B? stands for chlorine, KZ stands for methyl and VK Z stands for ethyl. b5 I'm about AB

Gu: y : what Y What r aa WE ey ta21o

M. Gr NVO in 70 tk Yan rze V V; this zm cuts

With hm p and how

Song Si

Also desirable are, in particular, compounds Ia211, especially compounds Ia211.1-(a211.64), which differ from compounds

Ha1.1-Ia1.64 tim, TsshovV? stands for chlorine, BZ stands for methyl and BZ stands for isopropyl. y I I : E t : i. what VE p how I where on zova

Ya en, Te zo SY(SNYAI» Well, Y F

Also desirable are, in particular, compounds Ia212, especially compounds Ia212.1-Ia212.64, which differ from compounds (a)

Ia1.1-Ia1.64 by what B? means chlorine, EZ means methyl and B C means tert-butyl. with ch- nie yet.

Ka i F. g. There is still a diooglii with shchi so A n u sk ptn - khz. And t 1 schi. ОДН " их чених и че что Я ba Kok Uk . в - Хо КЕ Bash s, Е и о Also desirable are, in particular, compounds Ia213, especially compounds Ia213.1-Ia213.64, which differ from compounds "so 050 . |a1.1-i81.64 by the fact that B? means chlorine, BZ means methyl and KZ means tert.-butyl. in particular, compounds Ia214, especially compounds Ia214.1-Ia214.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, EZ means methyl, B C means ethyl and B" means methyl.

Mega SHE dr tlagii

Mayor, ve 70 Y AD E | WITH.

Also desirable are, in particular, compounds Ia215, especially compounds Ia215.1-Ia215.64, which differ from compounds 75. |a1.1-Ia1.64 in that B? means chlorine, C means methyl, B "C is isopropyl and K"" methyl.

Persons as sho v koshchi Z vi ja sha ja es -6 pi pi NE oh di tazi

ENisSnUz sleep.

Also desirable are, in particular, compounds Ia216, especially compounds Ia216.1-Ia216.64, which differ from compounds (se) |a1.1-Ia1.64 in that B? means chlorine, KZ means methyl, K "Z means tert-butyl and B"" means methyl.

Also desirable are, in particular, compounds Ia217, especially compounds Ia217.1-Ia217.64, which differ from compounds 45. Ia1.1-Ia1.64 in that B" and BZ mean methyl and K2 means chlorine. and "aCe" Т. ши шт. што г ий шлоцой ж ев Ив ши ше: Ве 60 Also desirable are, in particular, compounds Ia218, especially compounds Ia218.1-Ia218.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and BZ mean methyl, K2 means chlorine and KZ means ethyl.

Ge ssh her a pra with.

Also desirable are, in particular, compounds Ia219, especially compounds Ia219.1-Ia219.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and BZ mean methyl, K2 means chlorine and KZ means isopropyl. F zoy | AN oz F an Tk y Uch: I am o

Also desirable E, in particular, compounds Ia220, especially compounds Ia220.1-Ia220.64, which differ from compounds |a1,1-Ii81,64 in that KE! and VZ mean methyl, B? means chlorine and ho means tert-butyl. - but Esh in a separate day "

I. and | and Still SV | sho - iy shsn)z SN

He) 20 Also desirable are, in particular, compounds Ia221, especially compounds Ia221.1-Ia221.64, which differ from compounds

Ф Ia1.1-Ia1.64 by the fact that B", BZ and B" mean methyl and B? means chlorine. Also desirable are, in particular, compounds Ia222, especially compounds Ia222.1-Ia222.64, which differ from compounds

Ia1.1-Ia1.64 because-K", BZ and B" mean methyl, VK? means chlorine and KZ means ethyl. scha Z: pn a y skh p

Me -- Ak Shchi o Sheya V cha Kk 70 M" nya on sv DY

Also desirable are, in particular, compounds Ia223, especially compounds Ia223.1-Ia223.64, which differ from compounds

Ia1.1-Ia1.b4 that B", BZ and "7 mean methyl, B? means chlorine and VZ isopropyl. this Sez og zkh dit ste o y---- vve y

SNISio JANV F "IV

Also desirable are, in particular, compounds Ia224, especially compounds Ia224.1-Ia224 64, which differ from compounds b

Ia1.1-181.64 in that vyv" means methyl, B? means chlorine and K"Z means tert-butyl. («in») ro o SN y 7 i yi- ih zo she kdd pad na ie SHU sho Tv Be not yet, krav chi,chnya shsh mal Yani i: el niy y: s zh Sov ih

SISNZI" ON. 15 se o -I Also desirable are, in particular, compounds Ia225, especially compounds Ia225.1-Ia225.64, which differ from compounds

Ф Іа1.1-Іа1.64 by the fact that ВК" means methylsulfonyl. p 5; и и ой zro de uh zh. Also: Й Й Be t. t i Ч и та ю ше и

Also desirable are, in particular, compounds Ia226, especially compounds Ia226.1-Ia226 64, which differ from compounds

Іа1.1-Іаі 64 in that КВ" means methylsulfonyl and В З means ethyl. b5

AS A yann-e ud ltazav: shk

Son OSY 18! MO ISTOTS,

Also desirable are, in particular, compounds Ia227, especially compounds Ia227.1-Ia227 64, which differ from compounds

Ia1.1-Iai 64 by the fact that B" means methylsulfonyl and B Z means isopropyl. ni g i t i g H t. :- iy x g dav vn tadau 7 i. g: : i i k . ; Ge slya iK: I niya snieneiz Zb3sNU F z son) i pi nevy i

Also desirable are, in particular, compounds Ia228, especially compounds Ia228.1-Ia228.64, which differ from compounds o

Ia1.1-Ia1.64 by the fact that B" means methylsulfonyl and B Z means tert.-butyl. pesh-iy ge leh o.

A "7 Y t oj - - STILL I she I -- pi. plzhast shh U Go " I About eO92sni 4 sn(snu with OSNa,

Ge) Also desirable are, in particular, compounds Ia229, especially compounds Ia229.1-Ia229.64, which differ from compounds about Ia1.1-Ia1.64 in that K"2 means methylsulfonyl and VK" means methyl.

Fo Ge. sii she: Still ShK se o oi and vn VV. aiv 60 scho Z otdti ma VOEN

Also desirable are, in particular, compounds Ia230, especially compounds Ia230.1-Ia230.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methylsulfonyl, B"C means ethyl and K"" means methyl. b5

OO go

All Zh oon nn V iz23y p shish schi Ya v. / Mk. in sex vv What is she YOU she

Kon BOEM

Also desirable are, in particular, compounds Ia231, especially compounds Ia231.1-Ia231.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means methylsulfonyl, B "Z means isopropyl and B" means methyl. s o, M A ketones yad lava a NI she: y yan nYA ih mch - vy T A: B shi In a dream (I will fall asleep o not o

Also desirable are, in particular, compounds Ia232, especially compounds Ia232.1-Ia232.64, which differ from compounds o

Ia1.1-Ia1.64 in that B" means methylsulfonyl, B C means tert-butyl and B" means methyl. (Se) sh ve ts ja sik Y PI PI o si. even wider HB 18239 « y yin Y ; " e sya ! iv: - r YAN. M Yanu BOasNU ts Susnazz

Also desirable are, in particular, compounds Ia233, especially compounds Ia233.1-Ia233.64, which differ from compounds

F Ia1.1-Ia1.64 by the fact that B" means methyl and K72 means methylsulfonyl.

Fo a about SIM 000 nn ord tovi yiv 3: about Mer I and V

Also desirable are, in particular, compounds Ia234, especially compounds Ia234.1-Ia234.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, VK? means methylsulfonyl and B"Z means ethyl. b5

NO MORE. not : With. shuy with all my might where E Z I - iY I

Shk: 502 sq.m

Also desirable are, in particular, compounds Ia235, especially compounds Ia235.1-Ia235.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, K 2 means methylsulfonyl and B"Z means isopropyl.

I I "ii I; (In and not, but them

My pelvis

Fo

Also desirable are, in particular, compounds Ia236, especially compounds Ia236.1-Ia236.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that "B" means methyl, K 2 means methylsulfonyl and KZ means tert.-butyl. that and Shan and I IY 15 OTIT in M shk -i Also desirable are, in particular, compounds Ia237, especially compounds Ia237.1-Ia237.64, which differ from compounds about Ia1.1-Ia1.64 in that B and B "" means methyl and B"? means methylsulfonyl. flat 7

Dyschi shchi aut i B. 000 yabUNU i

Also desirable are, in particular, compounds Ia238, especially compounds Ia238.1-Ia238.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? mean methyl, KV? means methylsulfonyl and B"Z means ethyl. b5

Uzh envi tagve 70 MK ro If - Z ih sne ZON; with

Also desirable are, in particular, compounds Ia239, especially compounds Ia239.1-Ia239.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? means methyl, K 72 means methylsulfonyl and BZ means isopropyl.

Places I - Y She in school 1 M. in zn z ko 0.0 ZOENu and z SNISNI F

Also desirable are, in particular, compounds Ia240, especially compounds Ia240.1-Ia240.64, which differ from compounds o

Ia1.1-Ia1.64 by the fact that B and B" mean methyl, B" means methylsulfonyl and BZ means tert-butyl. what is it -

SV oho and what , y and y is sha ped tabchv not

Also desirable are, in particular, compounds Ia241, especially compounds Ia241.1-Ia241.64, which differ from compounds 50 Ia1.1-Ia1.64 in that B? means ethylsulfonyl and B? means methyl sulfonyl. which differ from compounds Ia1.1-Ia1.64 in that B? means ethylsulfonyl, B? means methylsulfonyl and B C means ethyl. 70 And LE to her and and; every but

Gestures re; Also Yaku Ya Yan sho. what

TT. and others p p i y: AJ nn pi g pOOzne

I SN bOZsne

Also desirable are, in particular, compounds Ia243, especially compounds Ia243.1-Ia243.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, K2 means methylsulfonyl and KZ means isopropyl. , with se ra shk i;

In lin KN hv, U z SCHO Y two 5 t you aut t 50000 days ory ev taza o p Yaschy still I IS in y I a. Am I deep down: F

СН СНи СН ий

Also desirable are, in particular, compounds Ia244, especially compounds Ia244.1-Ia244.64, which differ from compounds р)

With 1а1.1-Іа1.64 what B? means ethylsulfonyl, B? means methylsulfonyl and KZ means tert-butyl. eat what In what I would and «| and not she 2 " Shk I li: ee KOMY I not g". 1 Mer bl susniurh PTaSNU av | NT pi we

Also desirable are, in particular, compounds Ia245, especially compounds Ia245.1-Ia245.64, which differ from compounds Ia1.1-Ia1.64 in that B? means ethylsulfonyl, K2 means methylsulfonyl and "Z" means methyl.

More about our pelvis:

And! y o t vouiezye

Also desirable are, in particular, compounds Ia246, especially compounds Ia246.1-Ia246.64, which differ from compounds 65 |811-a1,64 in that K2 means methylsulfonyl, K!2 means ethylsulfonyl, B means ethyl and BK"? means -7A-

methyl. here I am. int

She she Sha rt BOSve - rya happened

San VOSN; t

Also desirable are, in particular, compounds Ia247, especially compounds Ia247.1-Ia247.64, which differ from compounds

Ia1.1--41.64 what BC? stands for ethylsulfonyl, BC? means methylsulfonyl, B'Z means isopropyl and B/7 means methyl. what m AV? her і u BU What else KE Щ and more | | gyi nya pettninni p. U ddu be : I and she in.

Me F zolo 7. Eh, eat. ha or F (Se)

Also desirable are, in particular, compounds Ia248, especially compounds Ia248.1-Ia248.64, which differ from their compounds

Ia1.1-Iia1.64 what BC? means ethylsulfonyl, B? means methylsulfonyl, B'Z means isopropyl and B means methyl. in. | o Vbosnu session

Also desirable are, in particular, compounds Ia249, especially compounds Ia249.1-Ia249.64, which differ from compounds two a1.1-Ia1.64 in that VK! means methyl, K2? means ethylsulfonyl and K 2 means methylsulfonyl. (F) ko bo b5 o Is this nn taboo 70 Mer a Y od sov o. Mrs. VOEN h.

Also desirable are, in particular, compounds Ia250, especially compounds Ia250.1-Ia250.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, KE? means ethylsulfonyl, B? means methylsulfonyl and B" means ethyl. still bo iy oi 6 B . aya EN ke vechya svt: so 7 i sho pi mezh. in b» sanNe ROoSNh o (Se)

Also desirable are, in particular, compounds Ia251, especially compounds Ia251.1-Ia251.64, which differ from compounds m

Ia1.1-Ia1.64 in that B" means methyl, KE? means ethylsulfonyl, B? means methylsulfonyl and B" means isopropyl. . al Ichkch zh " yu a Sta de : svi dit Z7Z es Z in zhh g zodetl g" sho shi i nn VE. Taboo. - TSI she Y I Y de January)"!

Also desirable are, in particular, compounds Ia252, especially compounds Ia252.1-Ia252.64, which differ from compounds about Ia1.1-Ia1.64 in that КЕ" means methyl, K2 means ethylsulfonyl, B"? means methylsulfonyl and KZ means imi)tert-butyl. because b5

Dreaming of thirst 70 years old

Also preferred are, in particular, compounds Ia253, especially compounds Ia253.1-Ia253.64, which differ from compounds |a1.1-I81.64 in that B and B" mean methyl, KE? means ethylsulfonyl and B"? means methylsulfonyl. 7

M Kk o SN shk

ZSh: sch nZo o Eb IchIa253 (8)

And in? oyu (Se) | 9 50" So No "c)

SNI 5O2SNI (Se)

Also desirable are, in particular, compounds Ia254, especially compounds Ia254.1-Ia254.64, which differ from compounds h-

Ia1.1-Ia1.64 by the fact that B and E"" mean methyl, B? means ethylsulfonyl, B" means methylsulfonyl and BZ means ethyl.

IN? "

N y M o CH oo - s Hn zo is Ia?254

Vo

M. M. at 502SoNe

Ф И о С»Не 505СНз - о 50

Also desirable are, in particular, compounds Ia255, especially compounds Ia255.1-Ia255.64, which differ from compounds 4» Ia1.1-Ia1.64 in that B! and E"" mean methyl, BV? means ethylsulfonyl, B'? means methylsulfonyl and BZ means isopropyl.

F) name) because b5

M Kk o SN ol ns i. There is Ia255

Ek in

М.

Also preferred are, in particular, compounds Ia254, especially compounds Ia254.1-Ia254.64, which differ from compounds

Ia1.1--a1.64 by the fact that B! and K"" mean methyl, K2 means ethylsulfonyl, B" means methylsulfonyl and KZ means ethyl.

Wet Zo 0000 F il you in PI UDNNNY i-

Also desirable are, in particular, compounds Ia257, especially compounds Ia257.1-Ia257.64, which differ from compounds "to 181.1-181.64 in that B? means chlorine and B" means methylsulfonyl. -o

M: Ii t... Ne zho vek styu, : ry r en ay ote o Me ee ay a Shi: y I Shiya so 50 E is -

F i Che this sfshzhti,

SV: vOsnu 25 Also desirable are, in particular, compounds Ia258, especially compounds Ia258.1-Ia258.64, which differ from compounds

Gee! Ia1.1-Ia1.64 by what B? means chlorine, K2 means methylsulfonyl and KZ means ethyl. Also desirable are, in particular, compounds Ia259, especially compounds Ia259.1-Ia259.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, K"2 means methylsulfonyl and KZ means isopropyl.

Well y a OVK dikh o vy ke o "yavi re J er A 7 syste NA she | about the web

ШЧИ Shk hChaSn o

Also desirable are, in particular, compounds Ia260, especially compounds Ia260.1-Ia260.64, which differ from compounds o

Ia1.1-Ia1.64 by what B? means chlorine, K"2 means methylsulfonyl and KZ means tert.-butyl. "o 35 it is j a -d3 im sh viya re? yu t shsry Sha Okh : |, s for Z t I 00 8OBKt".

Ge) : a oapdtni Ya ay Zh ; and them

With c(Siya B: (se) 50 Also desirable are, in particular, compounds Ia261, especially compounds Ia261.1-Ia261.64, which differ from compounds

Ф Ia1.1-Ia1.64 by what B? means chlorine, K"2 means methylsulfonyl and KZ means methyl. (F) ko bo b5 sh gne Z t

Esh She: and Snu BOSNe

Also desirable are, in particular, compounds Ia262, especially compounds Ia262.1-Ia262.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, K"2 means methylsulfonyl, KZ means ethyl and KE"? means methyl.

CY iz and ots. ha and a TE . IN

Ha. SI - i zo IY: tiy re IY | those I kN this this at E soy zhk

NS o M nan is VH.

Zhedebe Zyi

S, sht, her ssha F son BOHSNU o I "co

Also desirable are, in particular, compounds Ia263, especially compounds Ia263.1-Ia263.64, which differ from compounds 39 |a1.1-Ia1.64 in that B? means chlorine, VC? means methylsulfonyl, KZ means isopropyl and K "7 means methyl.

For sv: ev SCHI and po zi Y I: -1 and Her that i

F | во ав) теше я чо яки з Чо со BLUE 42) Also desirable are, in particular, compounds Ia264, especially compounds Ia264.1-Ia264.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, K"2 means methylsulfonyl, KZ means tert-butyl and K"" means methyl. (Ф) ko) bo b5 shi Shan; oh You

Also desirable are, in particular, compounds Ia265, especially compounds Ia265.1-Ia265.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means methyl, B? means chlorine and KE"? means methylsulfonyl.

About OS vichiya

PA Y nn Tab sch i! with, : sly yi-oi

Also desirable are, in particular, compounds Ia266, especially compounds Ia266.1-Ia266.64, which differ from compounds Ha")

Ia1.1-Ia1.64 by the fact that B! means methyl, B? means chlorine, B? means methylsulfonyl and BZ means ethyl. so vo brya y y ve SA no : it: sek ke schu N K. ne Z n» Mkzhui UGA and ro-k de, OO E that " t h o s. 45 m still sa no clan, - tone BbUSnU ( 22) o Also desirable are, in particular, compounds Ia267, especially compounds Ia267.1-Ia267.64, which differ from compounds dr 181.11a1.64 in that B" means methyl, B? means chlorine, B7 means methylsulfonyl and BZ means isopropyl. (Se) i ryarorshnia in o z se cheneva A ; and oh that. And also kan y CHAN av ZY bo Sho 5 Y s 65 SS y

Also desirable are, in particular, compounds Ia268, especially compounds Ia268.1-Ia268.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, B? means chlorine, K 72 means methylsulfonyl and K "Z means tert-butyl. sv vh i ZA She t ab DA y 70 Y -Y 4 Y ШЭ: ke v t Е ДН я | vOohsna, " sisngz

Also desirable are, in particular, compounds Ia269, especially compounds Ia269.1-Ia269.64, which differ from compounds |a1.1-i81.64 in that B and B" mean methyl, K2 means chlorine and B" means methylsulfonyl. there are zv "M" and their o o ; yes em op te pu 7 y V 7 ku E So More KO Z TI zhk sl Ge) yar Te NN "VE o

Z X i; same Ge)

Also desirable are, in particular, compounds Ia270, especially compounds Ia270.1-Ia270.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B | VK" means methyl, KE? means chlorine, B"? means methylsulfonyl and KZ means ethyl. -«f also | wow and Kit tab70 with Y! Sweat x it. "And we're going to go to bed

E bat SHAH t i

F X5Ne WAR. 42)

Also desirable are, in particular, compounds Ia271, especially compounds Ia271.1-Ia271.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? means methyl, K2 means chlorine, K72 means methylsulfonyl and KZ means ethyl.

F) name) because b5

With 0byah alone; Niskh i o... el

ZED: 'N'; in With I in

ZY. . them and E (I de Y 8: Shy

Mods in. Kk 70 B 9 What ke y

Also desirable are, in particular, compounds Ia272, especially compounds Ia272.1-Ia272.64, which differ from compounds

Ia1.1-Ia1.64 in that KV"! and B"" mean methyl, B? means chlorine, BEZ means methylsulfonyl and BZ means tert-butyl.

N. of them from - 5 eh Zh o g. 1 30 1 "OSY o

С(СН5И in. Fo (Se)

Also desirable are, in particular, compounds Ia273, especially compounds Ia273.1-Ia273 64, which differ from compounds 35 |a1.1-Ia1.64 in that KE" means phenylsulfonyl. in kA CE de ze Ku « 40 and pt Y T shi are mk same and nn Ia373 : Mch, - s that I that l. shi PI sh from Fo vovnu o NU 50» SeNv: ee, In particular, compounds Ia274 are also desirable, especially compounds Ia274.1-Ia274. 64, which differ from compounds 4" Ia1.1-Ia1.64 in that K" means phenylsulfonyl and KZ means ethyl. (F) ko bo b5

And si And y ; and. 7 7 that Ped Yake o.

PSH I am VOASNA and SZNE BOZENE

Also desirable are, in particular, compounds Ia275, especially compounds Ia275.1-Ia275.64, which differ from compounds

Ia1.1-Ia1.64 in that K"2 means phenylsulfonyl and VK 3 means isopropyl. 20

Avt OV 25 I Щ Another g. seg logvvkovchtsyam, grya Ya Noy 7 she za cy z che y. and How porridge and Her. i Bea-ya s zo B stabs and How where I still and b what F o BOSIZ "BOesene: F ochi ich-

Also desirable are, in particular, compounds Ia276, especially compounds Ia276.1-Ia276.64, which differ from compounds Ia1.1-Ia1.64 in that КВ" means phenylsulfonyl and BZ means tert-butyl. C: » | That's me. 7 SHY l tavtv

F Ed TA tvo so 50 : y a: EE. OZONE" her ve and D:. a ime) Also desirable are, in particular, compounds Ia277, especially compounds Ia277.1-Ia277.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means phenylsulfonyl and B C means methyl. because b5

IN

Shy y r her I 7 X TM Sho Ya Ki same Y Ben sni It

Also desirable E, in particular, compounds Ia278, especially compounds Ia278.1-Ia278.64, which differ from compounds

Ia1.1-Ia164 because "VK" means phenylsulfonyl and VZ means isopropyl.

Saint BOS F

Also desirable are, in particular, compounds Ia279, especially compounds Ia279.1-Ia279.64, which differ from compounds o

Ia1.1-Ia1.64 in that B" means phenylsulfonyl, B C means isopropyl and B" means methyl. g. (Se) vs ryad I Chevuv 17 il y son - ik" vo Y what she is Tit sh t v: Vo i se aE . « 0 I Moscow Z: but,

And: su; BOS "" ; 1 st

BO and -I g ote,

Also desirable are, in particular, compounds Ia280, especially compounds Ia280.1-Ia280.64, which differ from compounds 181.1l1a1.64 in that 2" means phenylsulfonyl, B C means tert-butyl, and B" ? means methyl. (se) 4) (F) ko bo b5

Mk same V t. r r My about me Where and WHAT is not BOZZSNV. vOoSvn village oh tt y

Also desirable are, in particular, compounds Ia281, especially compounds Ia281.1-Ia281.64, which differ from compounds 20.a1.1-Ia1.64 in that they mean methyl and K"2 means phenylsulfonyl. For example: panych benches about with she

TNZ 5bosne o

Also desirable are, in particular, compounds Ia282, especially compounds Ia282.1-Ia282.64, which differ from compounds i-o |a1.1-Ia1.64 in that B! means methyl, KV? means phenylsulfonyl and BZ means ethyl. in. : I : More leoovsty -

OS I - ; siy rea ze Y 7zh ney in su -e KAMMNYA -

F and t. svt: " Ms. 7 the same: lei. her ben BOZEVN (Se) 250 Also desirable are, in particular, compounds Ia283, especially compounds Ia283.1-Ia283.64, which differ from compounds

F Ia1.1-Ia1.64 in that B" means methyl, VK? means phenylsulfonyl and KZ means isopropyl.

Also desirable E, in particular, compounds Ia284, especially compounds Ia284.1-Ia284.64, which differ from compounds |a1.1-I81.64 in that B! means methyl, EK"? means phenylsulfonyl and BZ means tert.-butyl. What are the bad things?

Me NI ve -y U chit her 3 . ChNU writes shi also in and in NYA F

Not yet - A : min Od, to Z. I at 5О5СНЙ F

VOHSvNe F z5 ry i-

Also desirable are, in particular, compounds Ia285, especially compounds Ia285.1-Ia285.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? mean methyl and B" means phenylsulfonyl. "- c .

JH OSNE see what T : o | the city of Sakoi. t Pn dov r VV tav b t En ye Y dam ko s v : | and eat

Snu VOVSBNO rya Ki Ot 7

GF) Also desirable are, in particular, compounds Ia286, especially compounds Ia286.1-Ia286.64, which differ from compounds 7 Ia1.1-Ia1.64 in that B" and B"? means methyl, K2 means phenylsulfonyl and KZ means ethyl. because b5 shi shi

NU dey otdvniai ich ve 70: Mekshchy de | I I I hi dkh oj sani BOSEN,

Also desirable E, in particular, compounds Ia287, especially compounds Ia287.1-Ia287.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B and B"" mean methyl, КВ? means phenylsulfonyl and VZ means isopropyl. rain for MORE

SV oh no. щ дытя и ШЕ sa Шчи я Е д я им х ж ли Е s: not "а и: чОБСН". - Z t K.. weights se I «I

And what mo t (is)

Also desirable are, in particular, compounds Ia288, especially compounds Ia288.1-Ia288 64, which differ from compounds o

Ia1.1-Ia1.64 in that B and B" mean methyl, K2 means phenylsulfonyl, and KE means tert.-butyl. ich-

НЯ и re Чи цк, test K-ynYa tagnv: - I El M i E 7 ie chy i: E and nn data Z Koty at I

And av | I'm soft

Also desirable are, in particular, compounds Ia289, especially compounds Ia289.1-Ia289.64, which differ from compounds with Ia1.1-Ia1.64 in that B? means ethylsulfonyl and B" means phenylsulfonyl. (F) ko bo b5

. ; Zo y o s M; ey a Ve av CHAN

In arszne same.

Also desirable are, in particular, compounds Ia290, especially compounds Ia290.1-Ia290.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, K2 means phenylsulfonyl and KZ means ethyl.

GO! i Y "va o i ESonv 505SENe F

Also desirable are, in particular, compounds Ia291, especially compounds Ia291.1-Ia291.64, which differ from compounds o

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, K2 means phenylsulfonyl and KZ means isopropyl. ise) p h-

UDO pd I I Iv them ak. o pOosone

E I - -I: in NI I sg, pe. that r: in | in Oatmeal

I would be a senfisheya szh, at 50 SP(SNnI). (se)

Ф Also desirable are, in particular, compounds Ia292, especially compounds Ia292.1-Ia292.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, B? means phenylsulfonyl and BZ means tert-butyl. (F) ko bo b5 what Od

SHOMC pok Vdya mienn Yash VV taza! Ozone /5 5 n

Also desirable are, in particular, compounds Ia293, especially compounds Ia293.1-Ia293.64, which differ from compounds 20. Ta1.1-Ia1.64 in that B? means ethylsulfonyl, K"2 means phenylsulfonyl and B" means methyl. shen yet shi aa ee: sch zo y I, ON F

SY O»OSYANV to her

Also desirable are, in particular, compounds Ia294, especially compounds Ia294.1-Ia294.64, which differ from compounds -

Ia1.1-Ia1.64 in that K2 means ethylsulfonyl, K"2 means phenylsulfonyl, KZ means ethyl and K"E means methyl.

WHAT SOVY I syak opt Z "» ns. sce. di ne ezh- ЖЯ oo. ly, shk BT I dya t B ve del rya V

The United Nations Office for Economic and Social Affairs: Also desirable are, in particular, compounds Ia295, especially compounds Ia295.1-Ia295.64, which differ from compounds

Ia1.1-Iia1.64 what BC? means ethylsulfonyl, B? means phenylsulfonyl, "B" means isopropyl and B means methyl. and she is not

Topeka as far as

Also desirable are, in particular, compounds Ia296, especially compounds Ia296.1-Ia296.64, which differ from compounds

Ia1.1--a1.64 by the fact that K2 means ethylsulfonyl, B" means phenylsulfonyl, BZ means tert-butyl and B! means methyl.

Mayor and , - - . iy sho Yad. nty pd what t (se) » 090070 ven s z5 e(nUya t

Also desirable are, in particular, compounds Ia297, especially compounds Ia297.1-Ia297.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, B? means ethylsulfonyl, K 72 means phenylsulfonyl. "

SHY n. ta397 mini: GOM res Y v EE o shu vbson: y n-luChN 4") y t "z t

Also desirable are, in particular, compounds Ia298, especially compounds Ia298.1-Ia298.64, which differ from compounds vv 1a1.1-a41.64 in that VK! means methyl, K7 means ethylsulfonyl, K7 means phenylsulfonyl and KZ means ethyl.

Che t basket writes wild and she MV and 70 Moge bra IN koeinny CHYNY

Sun ZVoSene

Also desirable E, in particular, compounds Ia299, especially compounds Ia299.1-Ia299.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that KE" means methyl, K2 means ethylsulfonyl, B"? means phenylsulfonyl and K"Z means isopropyl

Y: and | ; Her face More and more, and more and more. KZ pala I ay "ya I and Bosh ay Y shi to zt sia

Ozon F

And the priest

SNISNi)zh F y i-

Also desirable are, in particular, compounds IaZO0, especially compounds Ia300.1-Ia300.64, which differ from compounds

Ia1.1-1a1.64 in that K" means methyl, VK" means phenylsulfonyl and K"" means tert-butyl. s Benz zii: svntozhseshkh shi i chi ne ta500 :z» che zh g: s len vya yo yo i nya z i V ZY IL Ye TO. r | NO. | IT. She 7 Sheoiya and

F; YASNU govt.:

Also desirable are, in particular, compounds IaZO1, especially compounds Ia301.1-Ia301.64, which differ from compounds 22 |a1.1-I81.64 in that B and B2 mean methyl, B? means ethylsulfonyl and "B" means phenylsulfonyl.

On. gozhe kN p y I syny ne y Zhe VE: chazo1: - M Cho YN I Zh is che - : K t zhchh .

Where is 70 Meekr? sleep and: the course at the university in What school. VbSene "SNU az sieN: t to Also desirable E, in particular, compounds IaZO2, especially compounds Ia302.1-Ia302.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! and B"" mean methyl, KE? means ethylsulfonyl, B? means phenylsulfonyl and KZ means ethyl. Che J

S. ev, g still ek I A: no. ad ey ee d za ss

KE - like Y, and them. ' t ge | Ge) t o BOVSeN F p fanty p. tya t pd y Ge») sene BOBSeN. iy

Also desirable are, in particular, compounds IaZOZ3, especially compounds Ia303.1-Ia303.64, which differ from compounds "i

Ia 1.1-Ia 1.64 by the fact that B! and KE" mean methyl, B? mean ethylsulfonyl, B" means phenylsulfonyl and VZ means isopropyl. - 0 St dy « п п 5 яд ша н н ДН ия What else is here:

F o teOBKen

Rv with I Ben g» NIH ZAY

FO SNY) F. 4; Also desirable are, in particular, compounds Ia304, especially compounds Ia304.1-Ia304.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! and B"" mean methyl, KE? means ethylsulfonyl, B? means phenylsulfonyl and KZ means tert-butyl. (F) ko bo b5

More pain

ОО жи « and ШШ n yivZtsЯ «M NE o When I o, es son eh, I. same

BOOEvNe and

SN

Also desirable are, in particular, compounds IaZO5, especially compounds Ia305.1-Ia305.64, which differ from compounds dd at 181.1-181.64 in that B? means chlorine and B? means phenylsulfonyl.

M Y ne y z 5 y, nya: cha shih niy y y aa What "V. in tai yk with F su VOZOen o

Also desirable are, in particular, compounds IaZ0b, especially compounds Ia306.1-Ia306.64, which differ from compounds che

Ia1.1-Ia1.64 by what B? means chlorine, K2 means phenylsulfonyl and KZ means ethyl. in v and their sya bi her and cho "em o, with VA zh Y s shiny vn a Z , to her t I She khh cha pu: ta and I p tn that g, Sh drink, Still in I: .

F and Bu si. Also desirable are, in particular, compounds Ia307, especially compounds Ia307.1-Ia307.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, B? means phenylsulfonyl and VZ means isopropyl. (F) ko bo b5 and KO CHE. r: and |! BOSS.

Also desirable are, in particular, compounds IaZO8, especially compounds Ia308.1-Ia308.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, K"2 means phenylsulfonyl and K"Z means tert-butyl. sao A vi dk zva KE V s i s oi ey Kk. Te) sleep WE "WHAT de bi. I. - g a: ota Fo

Also desirable are, in particular, the compounds IaZ09, especially the compounds Ia309.1-Ia309.64, which differ from the compounds Ia1.1-Ia1.64 in that B? means chlorine , EK"? means phenylsulfonyl and K"" means methyl. и и С:8) и Шк Шко а з век Я каконни тазбе бу и , шча ШЧА niv: я пат Ки ; and they have a dream and she has something. ше (ав) 3 I - y I ' Her 2 I t that y

Leads the OP si

Ft 7

J

52 Also desirable are, in particular, compounds IaZ310, especially compounds Ia310.1-Ia310.64, which differ from compounds about Ia1.1-Ia1.64 in that B? means chlorine, K"2 means phenylsulfonyl, KZ means ethyl and K"" means methyl. ko bo b5

: Che sov Hey t Zh shoyu tsk ; . І І ши и . What is E: yah n br y ; Russian s B 2. s sht ks I ney 70 essays sx zas "ChNNY t bat.

Her Yi sSane WATER I

Also desirable are, in particular, compounds Ia311, especially compounds Ia311.1-Ia311.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, VE? means phenylsulfonyl, B"C means isopropyl and B" means methyl. o Shi YAN r. o vk de shchi.

See her and where

Vozsene: F z sho F

Also desirable are, in particular, compounds Ia312, especially compounds Ia312.1-Ia312.64, which differ from compounds (Ce) with 18a1.1-Ia1.64 in that VK" means chlorine, B"? means phenylsulfonyl, K": means tert.-butyl and VK"! means methyl. them i e t i g m in one sko KO. Om sh dkischo h write nn Te33 5

She is a dreamer

Ф Also desirable are, in particular, compounds Ia313, especially compounds Ia313.1-Ia313.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means methyl, B? means chlorine and EC"? means phenylsulfonyl. (F) ko bo b5

I'm sleeping, my dear

Oy one ny ta3Zi3 ie ik dk

Kesrre and fu " enu rise

Also desirable are, in particular, the compounds Ia314, especially the compounds Ia314.1-Ia314.64, which differ from the compounds go. a1.1-a1.64 by the fact that BE" means methyl, K2 means chlorine, VK? means phenylsulfonyl and B"Z means ethyl.

OO of Dyba's sleep

And her No E. simple se si y y nn In the basin o I Also: Her "in pestezhkre Sh y I bir s van kn: zv Sh (Se) zo M i in se si shu sho y selk BOhsen to her. Hai - - t "ya

Also desirable are, in particular, compounds IaZ315, especially compounds Ia315.1-Ia315.64, which differ from compounds |a1,1-Ii81,64 in that EK! means methyl, K2 means chlorine, B72 means phenylsulfonyl and KZ means isopropyl. - and and and 1 and zhk Zh n-

Z. ЭХ г ТХ. 7 and t sh y o Ivo b" ; re pa x J

RON

(av) . snIsniyiv,

Also desirable are, in particular, compounds Ia316, especially compounds Ia316.1-Ia316.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means methyl, B? means chlorine, K 72 means phenylsulfonyl and KZ means tert-butyl. (F) ko bo b5

Z Av ony yan VE taVIE 70 Zhov y e ne "Ve vbychye

SS in

Also desirable E, in particular, compounds Ia317, especially compounds Ia317.1-Ia317.64, which differ from compounds |a1.1-i81.64 in that B | B" means methyl, B? means chlorine and B" means phenylsulfonyl. z vek schi -M o yad : SHE where

The language of Fr

Also desirable are, in particular, compounds IaZ318, especially compounds IaZ318.1-Ia318.64, which differ from compounds i-o |a1.1-Ia1.64 in that B | B"" mean methyl, B? means chlorine, B? means phenylsulfonyl and BZ means ethyl. in. Send us a message to Bazi. no, 4. in: the wife of VOUSENV; o Also desirable are, in particular, compounds Ia319, especially compounds Ia319.1-Ia319.64, which differ from compounds a1.1-ia41.64 in that BK! | EC" means methyl, K? means chlorine, BC"? means phenylsulfonyl and B'Z means

I«e) and isopropyl. 42) (F) ko) bo b5 and ke; o shchi shchi pelvis; 7 Mine. in still ' p - o call Mak

Sconce. nose

Also desirable are, in particular, compounds Ia320, especially compounds Ia320.1-Ia320.64, which differ from compounds Ia1.1-i81.64 in that B! and B"- mean methyl, B? means chlorine, B? means phenylsulfonyl and "Z" means tert-butyl. N-. y y code She E nai Zh What 35 . with. . Academician

Also desirable are, in particular, compounds Ia321, especially compounds Ia321.1-Ia321.64, which differ from compounds "

Ia1.1-Ia1.64 by the fact that "V" means 4-methylphenylsulfonyl. for Ge a child -- I Be and not az

And NOT - that I. her I. And I. chases I

Fsk Shesly M

Also desirable are, in particular, compounds Ia322, especially compounds Ia322.1-Ia321.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means 4-methylphenylsulfonyl and B C means ethyl. (F) because b5 is not what B is; and it is more E - b ET. p. TV 7 p of the set: -tr Yak

I

Save 583 SON OF EV

Also desirable E, in particular, compounds Ia323, especially compounds Ia323.1-Ia323.64, which differ from compounds

Ia1.1-Ia1:64 in that K72 means 4-methylphenylsulfonyl and KZ means isopropyl. . the same 7 -4 i. zh n ry Kk shik DY and I Sh g a (in Y roya | E I . o zo | elka ek E o

Y de Ne skh: t PN o

Also desirable are, in particular, compounds Ia324, especially compounds Ia324.1-Ia324.64, which differ from compounds -

Ia1.1-Ia1.64 in that B" means 4-methylphenylsulfonyl and KZ means tert-butyl.

There is about -- | sheopishchoh 7 - and SHY ate it at. : и ИЗ "и! : Ko

Bowls and -i SH M I o I Y "BOZHNAU

F; vozi eena snaH so o i

F Feb

Also desirable are, in particular, compounds Ia325, especially compounds Ia325.1-Ia325.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means 4-methylphenylsulfonyl and K"Z means methyl. (F) ko bo b5

, go shi sha

Also preferred are, in particular, compounds Ia326, especially compounds Ia326.1-Ia326.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means 4-methylphenylsulfonyl, B C means ethyl and K"" means methyl.

Gee)

Also desirable are, in particular, compounds Ia327, especially compounds Ia327.1-Ia327.64, which differ from compounds

Іа1.1-Іа1.б4tim that VK" means 4-methylphenylsulfonyl, BZ means isopropyl and K"" means methyl. o

What (Se) 7 shu oh I

Sho n, o» y i Y , 1; And: two Also preferred are, in particular, compounds Ia328, especially compounds Ia328.1-Ia328.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that K"2 means 4-methylphenylsulfonyl, B C means tert.-butyl and EC"? means methyl. 4) (F) ko bo b5 porno te a; sun and sun at min: 9 Vesnu

SNU) from

Also desirable are, in particular, compounds Ia329, especially compounds Ia329.1-Ia329.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl and B? means 4-methylphenylsulfonyl.

Also desirable are, in particular, compounds Ia330, especially compounds Ia330.1-Ia330.64, which differ from compounds 32 |a1,1-i81.64 in that B! means methyl, B? means 4-methylphenylsulfonyl and BZ means ethyl. т щ и что « about SNU ve ne s c) s ! І T є и и при. :» sov dv no V. jazz: pom chshi HIGHER J sce Son yaoh(4-bn. bno o Also desirable are, in particular, compounds Ia331, especially compounds Ia331.1-Ia331.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl, B? means 4-methylphenylsulfonyl and BZ means isopropyl. tyu tt and cha

Vs le Not a

B 9 BOS. vema-dvh eq to ZHNTSNIYA

Also desirable are, in particular, compounds Ia332, especially compounds Ia332.1-Ia332.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl, B? means 4-methylphenylsulfonyl and BZ means tert-butyl.

I am her. that tez db dyi t even tazza 70 - | She: ! | 5.4. "I

Mayor, t

Also desirable are, in particular, compounds Ia333, especially compounds Ia333.1-Ia333.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? mean methyl and КВ? means 4-methylphenylsulfonyl.

Also desirable are, in particular, compounds Ia334, especially compounds Ia334.1-Ia334.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? mean methyl, K2 means 4-methylphenylsulfonyl and B "Z means ethyl.

F Zanb ovo (asSnUSNoh

F;

Also desirable are, in particular, compounds Ia335, especially compounds Ia335.1-Ia335.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? mean methyl, K 72 means 4-methylphenylsulfonyl and B "Z means isopropyl. (F) kobo b5 g K Zhe - I. I. НН 2 и

O SN uki iv soni

Also desirable are, in particular, compounds Ia336, especially compounds Ia336.1-Ia336.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" and B"? means methyl, K 2 means 4-methylphenylsulfonyl and BZ means tert-butyl. it is given, and we: Sh y o svdinya y s yita s ba which 7 - on her . tv t se al y i . IY M i : i

And Ge)

STnUKa about (Se)

Also desirable are, in particular, compounds Ia337, especially compounds Ia337.1-Ia337.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl and B" means 4-methylphenylsulfonyl. -

Я их с г Я " и . . . . . . . . . . . . . . . . . . . . . . . . . . which are different from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, K"2 means 4-methylphenylsulfonyl and ВЕ means ethyl. (Ф) kobo b5

- shk z VE o: s eh sn EY spodi li Ken tazzv shi she ee y

E 1. SOIU p. a m, bune Bozazsvysenuu t Also desirable are, in particular, compounds Ia339, especially compounds Ia339.1-Ia339.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, K2 means 4-methylphenylsulfonyl and KZ means isopropyl. ; : 7 sk tya y - nt - m ia i os h ko OzSone i bozbesneovM s F shchi : What what I Zh F shi(snUih Fo (Se)

Also desirable are, in particular, compounds Ia340, especially compounds Ia340.1-Ia340.64, which differ from compounds Ia1,1-Ii81,64 in that K2 means ethylsulfonyl, B? means 4-methylphenylsulfonyl and KZ means tert-butyl. - d sh as OV: y y . | yad - "» vyh shtogl. i yin Kniya . DN a tk oh U y I JHE E p zh what Is 7 ? le: No. I Sh ,

V Y and 00 VO UNe

F Y she high school. damn, hundreds of dogs -

Fo I bass sleep I 7

FO 1 ssh

F SEN h

Also desirable are, in particular, compounds Ia341, especially compounds Ia341.1-Ia341 64, which differ from compounds |a1.1-Ia1.64 in that KE? means ethylsulfonyl, B? means 4-methylphenylsulfonyl and B" means methyl.

F) ko bo b5

De KD che in pc taza.

Yara in dk iy i CHYN sleep Ben Odnu; Also desirable are, in particular, compounds Ia342, especially compounds Ia342.1-Ia342.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, K2 means 4-methylphenylsulfonyl and K"" means methyl.

Also desirable are, in particular, compounds Ia343, especially compounds Ia343.1-Ia343.64, which differ from compounds He»)

Ia1.1-Ia1.64 by what KV? means ethylsulfonyl, B" means 4-methylphenylsulfonyl, KZ means isopropyl and B/7 o means methyl. in Te 7 i e : I cheh 2 t Sheeha S, - Ne ay 7 | ba sno o 50

Also desirable E, in particular, compounds Ia344, especially compounds IaZ344.1-Iaz344.64, which differ from compounds 4 Ia1.1-Ia1.64 in that КВ? means ethylsulfonyl, B? means 4-methylphenylsulfonyl, VZ means TRVT, -butyl and

B" means methyl. (F. ko bo b5 oko B 95 oi see DK

Yani and nyu Wo khan ch0554-Snu SEN hЙ

SNU

Also desirable are, in particular, compounds Ia345, especially compounds Ia345.1-Ia345.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, B? means ethylsulfonyl, and B" means 4-methylphenylsulfonyl. from action

M pi i i U wai cm

SHCHI MO "VE nshI F : SHKYA TT - would

Also desirable are, in particular, compounds Ia346, especially compounds Ia346.1-Ia346.64, which differ from compounds o

3Z5 Ia1.1-Ia1.64 by the fact that B! means methyl, B? means ethylsulfonyl, B? means 4-methylphenylsulfonyl and BZ y- means ethyl. what with sk dya: "

TE YAETe. "And oil I g" p and in o tazaye

SHE "her" V. at University of St. Sen at 50

Also desirable are, in particular, compounds Ia347, especially compounds Ia347.1-Ia347.64, which differ from compounds with Ia1.1-Ia1.64 in that B" means methyl, B? means ethylsulfonyl, B"? means 4-methylphenylsulfonyl and BZ means isopropyl.

F) ime) bo b5 nsh zegaesnU bno) and shchi

SypsNNEh 7

Also desirable are, in particular, the compounds Ia348, especially the compounds Ia348.1-Ia348.64, which differ from the compounds go. 181.1-а1.64 by the fact that ВТ 8" means methyl, K2 means ethylsulfonyl, K/2 means 4-methylphenylsulfonyl and

In C stands for tert-butyl. 0 sna vyb h yu Modrychi cha as F y prah sn pec mature with ! vp en Jena) at 35 4 - chena and "

Also desirable are, in particular, compounds Ia349, especially compounds Ia349.1-Ia349.64, which differ from compounds c 40 |a1.1-I81.64 in that B! and B" represent methyl, B? represents ethylsulfonyl, and B" means 4-methylphenylsulfonyl. 8

Щ Her nya Y ШЭ ч nak. AK A0odenn-o vi haziy o 5 More, that TD oo

F 89 Vaughan

Snu vbhs-Sni seni z o Also desirable are, in particular, compounds IaZ50, especially compounds Ia350.1-Iaz50.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B and E"" mean methyl, B? means ethylsulfonyl, B? means 4-methylphenylsulfonyl and o B C means ethyl. because b5

What's up

Z Evu db vro SAME , t What / with groin tie and ik Bas te s -. 7 Ka - 7th. t 70 Me with : E: soKE ku dvy she on ke : I - o che rosy p. to and -o San zi SLEEP BEANS Sena)

Also desirable are, in particular, compounds IaZ51, especially compounds Ia351.1-Iaz351.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B and B"" mean methyl, B? means ethylsulfonyl, B? means the same thing that t-vo V zhk zey y 1. that : y shchi What I. shi NI dn taZ5U

I t Ge) en (Snu Fo (Se)

Also desirable are, in particular, compounds Ia352, especially compounds Ia352.1-Ia352.64, which differ from compounds |a1.1-i81,64 in that B and K" mean methyl, VK? means ethylsulfonyl, B? means 4-methylphenylsulfonyl and -

VZ stands for tert-butyl.

Wet weather

M SHE. Also desirable are, in particular, compounds Ia353, especially compounds Ia353.1-Ia353.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine and B" means 4-methylphenylsulfonyl. (F) ko bo b5 her the same ho.

I have 70 things in 1 : 1 more : d

Also desirable are, in particular, compounds Ia354, especially compounds Taz54.1-I8354.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, K"2 means 4-methylphenylsulfonyl, and KZ means ethyl. I'm what you are. I'm still here.

Sena Zb (a she. OYUNaH o sia: (Se)

Also desirable are, in particular, compounds Ia355, especially compounds Ia355.1-Ia355.64, which differ from compounds Ia1,1-Ii81,64 in that K2 means chlorine, K2 means 4-methylphenylsulfonyl and KZ means isopropyl. - boss blame "

I'M STILL I'm still in . -- zh -i in Mn ay i shii ts : p » Z t i, : | и L VE - ki и a gi и ше I E Ukfokeya garden I what pe

Fi: p

Fo sho noi

R V i Z M v zhi i

Also desirable are, in particular, compounds IaZ356, especially compounds Ia356.1-Iaz56.64, which differ from compounds |a1.1-Ia1.64 in that ЕВ? means chlorine, B" means 4-methylphenylsulfonyl and BZ means tert.-butyl. (F) ko bo b5 ssh SHO bo Mor i - 7

Nose "V. Vk y ; 1 4 vk i tik -gtuuE zhO5iacOnI Senya)

And the wife.

Also preferred are, in particular, compounds Ia357, especially compounds Ia357.1-Ia357.64, which differ from compounds |a1.1-I81.64 in that 2 means chlorine, B? means 4-methylphenylsulfonyl and "Z means methyl . i : With so: not sch

NO, that's it! g: m Y nya y shin t y - N I SCHI same again: sy

In the same ts DI two - gozhe liu av!

Jenz br - SNU Seny Fr

Also desirable are, in particular, compounds IaZ358, especially compounds Ia358.1-Iaz58.64, which differ from their compounds

Ia1.1--41.64 what K2? means chlorine, K"2 means 4-methylphenylsulfonyl, KZ means ethyl and KE"? means methyl. ож " :z" OT dya -- t ti - te -y what and Phi sey her "y kyy 7 y 4 ssh kah 5

I don't know where she is

KMekv de: g, yav sho, shcha (o) Also g. is what - eg strdti, srzh pshe zh o on BO" (ex Svn (se) 50 Also desirable are, in particular, compounds Ia359, especially compounds Ia359.1- Iaz59.64, which differ from compounds

Ф Ia1.1-Ia1.64 by the fact that K2 means chlorine, K/2 means 4-methylphenylsulfonyl, B "Denotes isopropyl and BC"? means methyl. (F) ko bo b5

VO and I her te She k-y tia"

ZhMzhv z a zu Her she that "is -

FROM KNU Ovniykh

Also desirable are, in particular, compounds IaZ360, especially compounds IaZ360.1-Ia360.64, which differ from compounds

Ia1.1-Iiai1.64 what BC? means chlorine, B" means 4-methylphenylsulfonyl, BZ means tert-butyl and B means methyl.

B Seam V This is AK, Sun. sh te oi oi nt stv ZhShchaZ00 ss

SYA B Shen NN le a zheni i i i - : wide se sih,

I OA -SNya -Senkh) F h y-

Also desirable are, in particular, compounds Ia361, especially compounds Ia361.1-Ia361.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl, B? means chlorine and B? means 4-methylphenylsulfonyl.

Yason tazbi at 4. Still Y vti 7 kh p SK Y; and eat and my self as I ogllh I and e still vya what same ii. la 2 4)

Also desirable are, in particular, compounds Ia362, especially compounds Ia362.1-Ia362.64, which differ from compounds 29 |a1.1-Ia1.64 in that B! means methyl, B? means chlorine, K 7? means 4-methylphenylsulfonyl and BZ means ethyl. (F) ko bo b5

"k:. 2 of them in, yes and again, with; SNU de and cha shchi ey What sknni and -ve zhav I. A ! z. i. and Three chschi y , 75 SG " In

Also desirable are, in particular, compounds IaZ63, especially compounds Ia363.1-Iaz363.64, which differ from compounds

Ia1.1-Ia1.64 in that VK" means methyl, BK? means chlorine, B? means 4-methyl-phenylsulfonyl and "Z" means isopropyl. sho -k nn nn i. ' yy Nikyty m te i y t Z i t Ge) I have anything fresh o u food o vOug4e ON Sen. oh sneonyaua. re I eat-

Also desirable are, in particular, compounds Ia364, especially compounds IaZ364.1-Iaz64.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, B? means chlorine | K!2 means 4-methylphenylsulfonyl and B"Z means tert-butyl. And "Oh, well. where! WITH

M. and (and her KE 415 t ve chishe I t 5

V. she ka

F in i4-sna. Sena) o Sena» d) Also desirable are, in particular, compounds IaZ365, especially compounds IaZ365.1-Iaz365.64, which differ from compounds

F Ia1.1-Ia1.64 because VK! and B" means methyl, B" means chlorine and K/7 means 4-methylphenylsulfonyl. and t Art. Also, in particular, compounds Ia366, especially compounds IaZ366.1-Ia366.64, which differ from compounds

Ia1.1-ia41.64 by the fact that KE" and 2"? mean methyl, BC? means chlorine, VK" means 4-methylphenylsulfonyl and BZ means ethyl. Sh a s ЧЕ і і ли жк She Kl ns Ak zh i Kon V schazb5 - sni ini ren ya: і че - ня і х іх

And in a dream Boz (a-Snu sen

Also desirable are, in particular, compounds Ia367, especially compounds Ia367.1-Iaz367.64, which differ from compounds

Ia1.1-Iai1.64 by the fact that K' and B" mean methyl, BK? means chlorine, B"? means 4-methylphenylsulfonyl and BZ means isopropyl.

OO with gifts of

Shk sna With SE 7 we with EE ve shchi ee a same CHOSHSHY z" 1 Bbzia-Snu Sena! F

Also desirable E, in particular, compounds Ia368, especially compounds IaZ368.1-Iaz68.64, which differ from compounds that

Ia1.1-Iai1.64 by the fact that K' and B" mean methyl, BK? means chlorine, B"? means 4-methylphenylsulfonyl and BZ means tert-butyl.

Ge poh v j sosok o, - Mody dn o BOBY SN YeIna o. 7 Ka nya Eish i. and SusSnz them

Also desirable are, in particular, the compounds Ia369, especially the compounds Ia369.1-Ia369.64, which differ from the compounds about Ia1.1-Ia1.64 in that K"Z means cyclopropyl. yyoch zhi son - also y y hya y deya y g vyia SA : y ke b v

Also desirable are, in particular, compounds Ia370, especially compounds Ia370.1-Ia370.64, which differ from compounds

Ia1.1-Ia1.64 in that KZ means cyclopropyl and K"" means methyl. x rom pairs; g: on g. E B. gas Ge (Se)

Also desirable are, in particular, compounds Ia371, especially compounds Ia371.1-Ia371.64, which differ from compounds i-

Ia1.1-Ia1.64 by the fact that B! means methyl and BZ means cyclopropyl. shk YushV; at 40 p.m. s Z y - Mei U Y Shi shsh s SHIN zan yivati. I! ish; in -I L and mn ! in uni approx. BOZZSNV (e)) : about ХХ. with 50 Plys

FO Also desirable are, in particular, compounds Ia372, especially compounds Ia372.1-Ia372.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means methyl, KE "Z means cyclopropyl and K" means methyl. (F) ko bo b5

Z ME z v ih still so vs A i- en KV tnZ7

Кк кН Е и в В Я border: no . i I: zu i. I nnia 70 th, pi I chi: Y sec Osn: 18 More ZM

Also desirable are, in particular, compounds Ia373, especially compounds Ia373.1-Ia373.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means trifluoromethyl and BZ means cyclopropyl. one more well and what with shchi ih pe U. What and sect I, Bl o Bk t

Sha nina oh shi eh

NO ste esvsst I - Z pit slo Pp we on DY zh: YSHY she " BOzsNU o r F

Also preferred are, in particular, compounds Ia374, especially compounds Ia374.1-Ia374.64, which differ from compounds O |a1.1-Ia1.64 in that B" means trifluoromethyl, K C means cyclopropyl and B"" means methyl .

ОО ЕРУ ай « о web. rmy writes in VD taz s Well and - whether and k still and and Yensssya and U" om i "V - ved shi ZHY. le i"? nya 1" | WHAT ABOUT "DV.

There are about 50 of them

Also desirable are, in particular, compounds Ia3.75, especially compounds Ia375.1-Ia375.64, which differ from 4) compounds Ia1.1-Ia1.64 in that B" means methoxy and KZ means cyclopropyl. (F) ko because b5 o base you

Kai Yani Even in what Sh | - vet - kre 5, ko- z

Also desirable are, in particular, compounds Ia376, especially compounds Ia376.1-Ia376.64, which differ from compounds

Ia1.1-Ia1.64-by what B! means methoxy, KZ means cyclopropyl, and K" means methyl. What do you know? Giving a son, lush; PIDE Thes.

NICK. re In te3z't5 h

IP i i T and 2 are zhi : t Sun

WHAT EK KE O S SHSH I'M A WAR."

Zhish » A F

Also desirable are, in particular, compounds Ia377, especially compounds Ia377.1-Ia377.64, which differ from compounds (se)

Ia1.1-Ia1.64 by what B? means ethylsulfonyl and BZ means cyclopropyl. whatever I and i8 I and sho , with ol ry te with on Ko. Theses about

KE puppy Oz Son - U

Ф ХХ r I (se) 50 Also desirable are, in particular, compounds Ia378, especially compounds Ia378.1-Ia378.64, which differ from compounds

Ф Ia1.1-Ia1.64 by what B? means ethylsulfonyl, KZ means cyclopropyl and VC " means methyl.

Also desirable are, in particular, compounds Ia379, especially compounds Ia379.1-Ia379.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means methyl, B" means ethylsulfonyl and KZ means cyclopropyl.

Mesveitn and her t ON fall. oh

Also desirable are, in particular, compounds Ia380, especially compounds IaZ380.1-Iaz80.64, which differ from compounds 20.a1.1-a1.64 in that K' means methyl, B" means ethylsulfonyl, K? means cyclopropyl and K""! means methyl. 00 sv. de s V ShK I p Ta389 0

Yan sho Y ju CHI y, sk - ny. sia 5 "de iya i ii ge)

She shi She sl also F zo EE will eliminate: (o)

Also desirable are, in particular, compounds IaZ381, especially compounds IaZ381.1-Iaz81.64, which differ from compounds -

Ia1.1-Ia1.64 in that B" means trifluoromethyl, K2 means ethylsulfonyl and B"Z means cyclopropyl. 0 СР вы ю я 7, шчеея И. -о јей фо чув кіш BOdSUNe so R oaya 4) Also desirable are, in particular, compounds Ia382, especially compounds Ia382.1-Iaz382.64, which differ from compounds

Ia1.1-Iiai1.64 by what KE! means trifluoromethyl, B? means ethylsulfonyl, B'C means cyclopropyl and B" means methyl.

F) ko bo b5 na msho - i Sta i dya: iya - sa i chi ve ta

Are you her wife? ; ok soee with and Eya and and with BOB UNe, 7

Also preferred are, in particular, compounds Ia383, especially compounds Ia383.1-Ia383.64, which differ from compounds uy Ia1.1-Ia1.64 in that B" means methoxy, K2 means ethylsulfonyl and B"Z means cyclopropyl. y g Sk more, Y Ve she Rzd cha

With th / th | and sho 1: and Urich Ge

TO the bottom I kb" about zo and from BOrSZN . F 7 p. and av

GA with (Se)

Also desirable are, in particular, compounds Ia384, especially compounds IaZ384.1-Iaz84.64, which differ from compounds h-

Ia1.1-Ia1.64 in that BK" means methoxy, B? means ethylsulfonyl, B'Z means cyclopropyl and B"? means methyl. p shk, their v Ost u dk y c) s zalo - : t - J 4 what ; za o bjzhI MANNYA - and vyya SCHE - sya: Sh v y t u. ra szh tii Ex

F So VOoSene («c) - x th 7 shk. 4)

Also desirable are, in particular, compounds Ia385, especially compounds IaZ385.1-Iaz85.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine and K"Z means cyclopropyl. (F) ko bo b5

"and stand t"

Eh and

Also desirable are, in particular, compounds Ia386, especially compounds IaZ386.1-Iaz86.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, B C means cyclopropyl and B" means methyl. and o, code

About the seam: І E І ц І Ш zn o ley id en ya Yo ay t vvi o: SHISHKU i t A: a . R, Ya

J. (about)

Also desirable are, in particular, the compounds Ia387, especially the compounds Ia387.1-Ia387.64, which differ from the compounds i-oi |a1.1-Ia1.64 in that B" means methyl, B? means chlorine and KZ means cyclopropyl . - - S 7. 4 ku u She iniy ih 1 i: E . "he tru: i" p Hu "M: pi z. pi i sei i what pe "JHE: i o-sh ok t, z

F 4.

Fo and o 50 Y 4") Also desirable are, in particular, compounds Ia388, especially compounds Ia388.1-Ia388.64, which differ from compounds Ia1.1-Ia1.64 in that B" means methyl, K2 means chlorine, KZ stands for cyclopropyl and K"? means methyl. (F) ko bo b5

F - th - 7 K Y, | . the same

Well, my son has a son: I have a bad temper and I have a nose; sh. GP I am shcha x t Ted 7 Shchi en y t Eh i she Shto Yaysk SCHI piny. then | rank 2

Also desirable are, in particular, compounds Ia389, especially compounds IaZ389.1-Iaz89.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means trifluoromethyl, B? means chlorine and B C means cyclopropyl. more, more, more, more, more

mine g san for S shchi hangs Mk Y what Ge)

A, F 3o EX. F (av)

Also desirable are, in particular, compounds Ia390, especially compounds Ia390.1-Ia390.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means trifluoromethyl, K2 means chlorine, KZ means cyclopropyl and K"" means methyl.

E SCHE Chi Resl NN Hek I still and eat

F hak o t - o 20 Also desirable are, in particular, compounds Ia391, especially compounds Ia391.1-Ia391.64, which differ from

Fu Ia1.1-Ia1.64 by the fact that B" means methoxy, VK? means chlorine and VK"? means cyclopropyl. oh"

I and Pain and

A и " . ltviv ay, neck Ya Ok sh bo

Also desirable are, in particular, compounds Ia392, especially compounds Ia392.1-Ia392.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methoxy, K2 means chlorine, KZ means cyclopropyl and K"? means methyl. b5 i Ж g ещ с У ШИ - horror "Mk. re i ha dele Zk i: still I that | He is her

Also desirable are, in particular, compounds Ia393, especially compounds Ia393.1-Ia393.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means trifluoromethyl and BZ means cyclopropyl.

SHO anna. kha383 in ov and YN » A F

Also desirable are, in particular, compounds Ia394, especially compounds Ia394.1-Ia394.64, which differ from compounds (Ce) zvo 181.1181.64 in that B! means trifluoromethyl, B C means cyclopropyl and B" means methyl. m "zh. i. ee; B :7 B

VO about "

V y -y Vu;

F Ga : (av)

He) 20 Also desirable are, in particular, compounds Ia395, especially compounds Ia395.1-Ia395.64, which differ from compounds

F Ia1.1-Ia1.64 by the fact that B" means methyl, B? means trifluoromethyl and KZ means cyclopropyl. (F) ko bo b5

1 "To What; osno E ho sn sy I with what y yah. Chi pt y tya t a, Kon Ko Iaz9b yu o Mem ei yi kl SE;

Her and: Y

Also desirable are, in particular, compounds Ia396, especially compounds Ia396.1-Ia396.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, B? means trifluoromethyl, KZ means cyclopropyl and B"7 means methyl. i i vo mo V ra NN a otv taz sch still i 1 I |; ! Where

Mayor of Shch; still Sean I so /d o ve Eh o

Also desirable are, in particular, compounds Ia397, especially compounds Ia397.1-Ia397.64, which differ from compounds (Ce) zvo 181.1181.64 in that B and B? means trifluoromethyl and B C means cyclopropyl. m

BO shiya that 7 th E- that ksheno s dae y kin ta357 "» nn tn ptzh tv Ra Pet y: shock i what ii sake u 15 I ee in . t - cha i shogo

Ge") h o i o 50

Ф Also desirable are, in particular, compounds Ia398, especially compounds Ia398.1-Ia398.64, which differ from compounds

Ia1.1-Ia1.64 in that B" and B? mean trifluoromethyl, VK C means cyclopropyl and B" means methyl.

Mon

GF) DE. cha M y Ne shkooi ti: lie down

Kh. 65th

Also desirable are, in particular, compounds Ia399, especially compounds Ia399.1-Ia399.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methoxy, K2 means trifluoromethyl and KZ means cyclopropyl.

SHY SCHO Chin Iazov 70; 1 E | | With shk where

Kerr i shchi she shi i: SHY

KK

Also desirable are, in particular, compounds Ia400, especially compounds Ia400.1-Ia400.64, which differ from compounds

Ia1.1-Iai1.64 by the fact that K' means methoxy, B? stands for trifluoromethyl, B'Z stands for cyclopropyl and B" stands for methyl. sho Ob de

NOT. M NI in such a way

KD. Her where am I g Ge")

Ak o

Also desirable are, in particular, compounds Ia401, especially compounds Ia401.1-Ia401.64, which differ from compounds che

Ia1.1-Ia1.64 in that VZ means chlorine and E"Z means cyclopropyl. mo 0 « o si al - s vo tadop1 z

Vo

M from M

In he BO»SNZ (e)) o c1 o 50 o Also desirable are, in particular, compounds Ia402, especially compounds Ia402.1-Ia402.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that BZ means chlorine, B C means cyclopropyl and B" means methyl. (F) ko bo b5

M Kk o si ol

Nzo

With | And in IchIa402 1 year before

M. -P 710 M On 5OzSNI si

Also desirable are, in particular, compounds Ia403, especially compounds Ia403.1-Ia403.64, which differ from compounds

Ia1.1-Ia1.64 by what KV? means ethylsulfonyl, BZ means chlorine and BZ means cyclopropyl. 7 e M 8; 71 oo in o

M. M on 5O2gSzN F

Fo si o (Se)

Also desirable are, in particular, compounds Ia404, especially compounds Ia404.1-Ia404.64, which differ from compounds i-

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, BZ means chlorine, BZ means cyclopropyl and B" means methyl. 1 "

M Kk (o) s 1 o - -E shsh s ns khz» Eb IabO4 5

ME K.

Ф 802 No (ав) ря си (се) 0 Also desirable are, in particular, compounds Ia405, especially compounds Ia405.1-Ia405.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" | EZ mean methyl and KZ means cyclopropyl. (F) ko bo b5

M V o SNI Ol ve tTa405 these | IS? co with 70 M

ON

ZOoOSNI - 3

Also desirable are, in particular, compounds Ia406, especially compounds Ia406.1-Ia406.64, which differ from compounds

Ia1.1-Ia1.64 in that B", BZ | B"" mean methyl and KZ means cyclopropyl. t

M Kk zo ta«06 de a (o) m! | Vo t-k Ga zo 8Ozon" F"

SN o (Se)

Also desirable are, in particular, compounds Ia407, especially compounds Ia407.1-Ia407.64, which differ from compounds i-

Ia1.1-Ia1.64 in that B", BZ | E"" mean methyl and BZ means cyclopropyl. 7

M ve o SNz zlo «-s de Iai407. in» " | ; VE

M

M ON

-I 58022 H5 (e)) at SNI at 50

FO Also desirable are, in particular, compounds Ia408, especially compounds Ia408.1-Ia408.64, which differ from compounds

Ia1.1-Ia1.64 in that B", 31 B"" means methyl, K2 means ethylsulfonyl and K"Z means cyclopropyl. (F) what about the sleep THESE "We are ta408 ki | so 710 M OH 5OzSzNE

SNU

Also desirable are, in particular, compounds Ia409, especially compounds Ia409.1-Ia409.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B | EZ mean methyl, B? stands for chlorine and VZ stands for cyclopropyl. -

M EE and r Ia409

AI at 5

MU. m KE o

ON I

C (Se) (av)

Also desirable are, in particular, compounds Ia410, especially compounds Ia410.1-Ia410.64, which differ from compounds of

Ia1.1-Ia1.64 by the fact that B", BZ | "E mean methyl, B? stands for chlorine and KZ stands for cyclopropyl. - - . 72

M Kk o; SN loz « yu S vo ta410 no s | I

From" | EE

M Hn! he zb1 -I

F SNZ av) i

Also desirable are, in particular, compounds Ia411, especially compounds Ia411.1-Ia411.64, which differ from compounds i-o Ia1.1-Ia1.64 in that B" means methylsulfonyl and KZ means cyclopropyl. 4) (Ф ) co bo b5 axis Mo y | o m -k- to iasia 5 70 M M Kk 5O0oSNU

BozSNZ

Also preferred are, in particular, compounds Ia412, especially compounds Ia412.1-Ia412.64, which differ from compounds 20.81.1-1a164 in that "2 means methylsulfonyl, KZ means cyclopropyl and KE" means methyl. o c1 I A (0! - p

N. p

Shi Ro Fr

Me ki

Eat! 5ОзСНз о (Се) 5О02СНЗ Etc

Also desirable are, in particular, compounds Ia413, especially compounds Ia413.1-Ia413.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B! means methyl, VC? means methylsulfonyl and K"Z means cyclopropyl.

F M o o 5ZzSNyaI o 50

F 503

Also preferred are, in particular, compounds Ia414, especially compounds Ia414.1-Ia414.64, which differ from compounds 59 |a1.1-Ia1.64 in that B and B" mean methyl, VE? means methylsulfonyl and BZ means cyclopropyl (F) ko bo b5

I-I

Sya dih o Z o - ns ko ta414

Id vo ik - that's 202SNa 505SNUZ

Also desirable are, in particular, compounds Ia415, especially compounds Ia415.1-Ia415.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means ethylsulfonyl, B? means methylsulfonyl and KZ means cyclopropyl. ! no skis and their Shess J

ZhK y n-eeve YiaYV village

Si shi shi in zo I and BOZZONE and what

Her from their BOS about

Also desirable are, in particular, compounds Ia416, especially compounds Ia416.1-Ia416.64, which differ from compounds c.

Ia1.1-Ia1.64 in that K2 means ethylsulfonyl, K'2 means methylsulfonyl, BZ means cyclopropyl and B means methyl. « o s1 MA - s oto: . g» nzs ve ta416 | | co

F o 502szH o | 2-25 at 50

F 50zSNI

Also preferred are, in particular, compounds Ia417, especially compounds Ia417.1-Ia417.64, which differ from compounds a1.1-Ia1.64 in that B" means methyl, KV? means ethylsulfonyl, B"? means methylsulfonyl and K"Z means cyclopropyl. (F) ko) bo b5

Mine to Ia417 these | then -

Nm) o

Z0zSaNe

ЗО2СНз

Also desirable are, in particular, compounds Ia418, especially compounds Ia418.1-Ia418.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B and E"" mean methyl, B? means ethylsulfonyl, B" means methylsulfonyl and BZ ho means cyclopropyl. 5 ven x B" n.e. SHE She sch

Why not and how I F 1 about thing Me)

Well, thanks to VI. "co

BOYEN

-

Also desirable are, in particular, compounds Ia419, especially compounds Ia419.1-Ia419.64, which differ from compounds

Ia1.1-Ia1 64 by what B? means chlorine, K2 means methylsulfonyl and KZ means cyclopropyl. " and c1 M in! - s ot -- . ». ' ) sh-- vo tia419 | ' - mi Vo

F She o si

F o 50 in 505СНa

Also desirable are, in particular, compounds Ia420, especially compounds Ia420.1-Ia420 64, which differ from compounds

Ia1.1--41.64 what K2? means chlorine, K"2 means methylsulfonyl, KZ means cyclopropyl and BK"? means

F) methyl. co bo b5

M Kk o s1 0-t

Nose 5 cht84120 m! | And - 70 | about se1

BOSS

Also desirable are, in particular, compounds Ia421, especially compounds Ia421.1-Ia421.64, which differ from compounds

Ia1.1-Ia1.64 by the fact that B" means methyl, K2 means chlorine, VK? means methylsulfonyl and BZ means cyclopropyl.

From A. |. i (2) and | o 0zsSiv; with h-

Also desirable are, in particular, compounds Ia422, especially compounds Ia422.1-Ia422.64, which differ from compounds

Ia1.1--a1.64 by what K" ii EK"? mean methyl, K2 means chlorine, BC" means methylsulfonyl, KZ means cyclopropyl. "

M in? - s o SN al g» ns

From ve Ia422

F. M. M

(av) o; -t si o 50 4) 502SNZ

Also desirable are, in particular, compounds Ia423, especially compounds Ia423.1-Ia423.64, which differ from compounds about Ia1.1-Ia1.64 in that B" means 4-methylphenylsulfonyl and KZ means cyclopropyl. ko bo b5

Gchi Kk

Y Y I r up to 70 M -- M p o 502СН3

AND

502(4-CH3-SeNi)

Also desirable are, in particular, compounds Ia424, especially compounds Ia424.1-Ia424.64, which differ from compounds

Ia1.1-Ia1.b4tim that VE? means 4-methylphenylsulfonyl, VK Z means cyclopropyl, and K" means methyl. Also -КЯ пай Ша я 0.

Sea And for: and - and We still go Ge) p vozenh - | in Ash at 70 BOYAesNnU: SNO F -

Also desirable are, in particular, compounds Ia425, especially compounds Ia425.1-Ia425.64, which differ from compounds

Ia1.1-Ia1.64 in that B" means methyl, K 2 means 4-methylphenylsulfonyl and B"Z means cyclopropyl. "

M E?7 -o s o CH ol . and - | | eh

F M

M o o 50zСН»5 o 50 | 4) 5Oz14-CHZ-SeNa 59 Also desirable are, in particular, compounds Ia426, especially compounds Ia426.1-Ia426.64, which differ from compounds (F. Ia1.1-Ia1.64 in that B" and B" ? mean methyl, K 72 means 4-methylphenylsulfonyl and BZ means cyclopropyl.

M Kk shchi o Snz det 95 3 ve tTa426 ki | in her-

M o 505СН3 ' " 503(4-SNI-SeNa)

Also desirable are, in particular, compounds Ia427, especially compounds Ia427.1-Ia427.64, which differ from compounds

Ia1.1-Ia1.64 by what B? means chlorine, K"2 means 4-methylphenylsulfonyl and KZ means cyclopropyl. in a", about with c and for Z.

Ki E Yi shi yi-v. 7 -4. u z o F «E- KE xx I t. sho zv Ov (4-SNI-SeNiu ze

Also desirable are, in particular, compounds Ia428, especially compounds Ia428.1-Ia428 64, which differ from compounds "

Ia1.1-Ia41.64 what BC? means chlorine, BC" means 4-methylphenylsulfonyl, B'"Z means cyclopropyl and BZ 70 means methyl. s z» i M v p 8) si alo -1 nzs kb I2a428 (e)) her AI! in o o o si and A

BO" (4-СНа-СеНа) o Also desirable are, in particular, compounds Ia429, especially compounds Ia429.1-Ia429.64, which differ from compounds Ia1.1-Ia1.64 in that K' means methyl, B ? means chlorine, K/2 means 4-methylphenylsulfonyl and B"Z means cyclopropyl. b5 is the base M

З - г и о Та479 vo nin ikh s1 805414-SNiZ-SeNa)

Also desirable are, in particular, compounds Ia430, especially compounds Ia430.1-Ia430 64, which differ from compounds 81.1-a1.64 in that B and 8" mean methyl, BK? means chlorine, B"? means 4-methylphenylsulfonyl and BZ means cyclopropyl. ha sya kg action - shi her on E and again DN Z - and sch

Kk y F zo y "v t NI

For I prebod s vdfu Wanshu zh (Te) zh kv peneoy SHA OSHNYA deya I Sen; EE. h- 3-(4,5-dihydroisoxazol-5-yl)/benzoylpyrazoles of the formula | can be obtained in different ways, for example in the following way:

Method A: "

Interaction of pyrazoles of the formula I (where 2-H) with activated benzoic acid IP" or benzoic acid pt") with Ps, which is preferably activated by ip ziz, with the receipt of an acetylation product and subsequent rearrangement.

Best i er -i k ; (22) / tey - and her Ese: shk shi shva

F vk Nv yak, an zhom ki z I X - vii s CI shcha U - VE - ayu , E

Ge) 1 HORSE in Hv. " ve he) shi she sn v r Ya ide bo mi. TA OO viz eYA ! i yi B," NE 65 Й7 means a nucleophilically displaced leaving group, such as halogen, for example, bromine, chlorine, hetaryl, for example, imidazolyl, pyridyl , carboxylate, for example, acetate, trifluoroacetate, etc.

Activated benzoic acid can be used directly, as in the case of benzoyl halides, or it can be prepared in situ, for example, with compounds such as dicyclohexylcarbodiimide, triphenylphosphanoic acid/azodicarboxylic acid ester, 2-pyridine sulfide/triphenylphosphane, carbonyldiimidazole, and TA .

If necessary, it may be advantageous to carry out the acetylation reaction in the presence of a base. Reagents and auxiliary base are used in equimolar amounts. A slight excess of auxiliary base, for example, from 1.2 to 15 molar equivalents per compound II, may provide advantages under certain conditions. 70 Tertiary alkylamines, pyridine or alkali metal carbonates can be used as auxiliary bases. Solvents that can be used are, for example, chlorinated hydrocarbons such as methylene chloride, 1,2-dichloroethane, aromatic hydrocarbons such as toluene, xylene, chlorobenzene, ethers such as diethyl ether, methyl tert-butyl ether, tetrahydrofuran, dioxane, polar aprotic solvents such as acetonitrile, dimethylformamide, dimethylsulfoxide or esters such as ethyl acetic acid or 7/5 mixtures thereof.

If benzoyl halides are used as an activated carboxylic acid component, it may be advisable to cool the reaction mixture to 0-102C when adding this component. After that, the reaction mixture is stirred at 20-1009C, preferably at 25-502C7, until complete conversion. Separation of the reaction mixture is carried out in the usual way, for example, the reaction mixture is poured into water the target product 2o is extracted. In particular, methylene chloride, diethyl ether and ethyl acetate can be used as a solvent. After drying the organic phase and removing the solvent, the crude ether can be used for rearrangement without further purification. Rearrangement of the complex ether to obtain compounds of the formula | it is expedient to carry out at a temperature from 20 to 40 92C in a solvent and in the presence of a base, and also, if necessary, with the help of a cyano compound as a catalyst. Ge

As a solvent, you can use, for example, acetonitrile, methylene chloride, 1,2-dichloroethane, dioxane, complex ethyl ester of acetic acid, toluene or mixtures thereof. Preferred are acetonitrile, dioxane dimethoxyethane.

Suitable bases can be tertiary amines, such as triethylamine, pyridine, or alkali metal carbonates, such as sodium carbonate, potassium carbonate, which are preferably used in equimolar (Ce) amounts or in excess of up to four times the ester. It is preferable to use triethylamine or alkali metal carbonates, preferably in an equimolar amount with respect to the ester. F

In the function of cyano compounds, inorganic cyanides are used, such as sodium cyanide, calcium cyanide, and organic cyano compounds, such as acetone cyanohydrin, trimethylsilicyanide. They are used in an amount from 1 to 5Omol. -o, for example, in an amount from 5 to 15, preferably 1Omol.9o, in terms of complex ether. -

Separation of the reaction mixture is carried out in a known manner. The reaction mixture is acidified, for example, with a dilute mineral acid, such as 5906 hydrochloric or sulfuric acid, and extracted with an organic solvent, for example, methylene chloride, acetic acid ester. The organic extract can be extracted with a 5-10956 alkali metal carbonate solution, for example, sodium carbonate or 70 potassium carbonate solution. The aqueous phase is acidified and the precipitate formed is suctioned off and/or extracted with methylene chloride or ethyl acetic acid, dried and concentrated (examples of obtaining esters of hydroxypyrazoles | rearrangement of esters are given, for example, in EP-A 282944 and 5 "» 4643757).

It is also expedient to obtain crude complex ester ip zysh | carrying out the rearrangement reaction without isolating and purifying the ester. -and Method B.

Ф Interaction of 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles of formula I! (where B 12-H) with the compound of formula M: ((c) o 50 42)

F) ime) 60 b5 then: cheek in . : 7 i - VU: s Ж s DE T t Ti she she: i tu Zk I I ate 4: І в: E ono tpyuriy vo de sk: shcha xx F

I Z led Oy ro

AND? means a nucleophilically displaced leaving group such as bromo, chlorine, hetaryl, eg imidazole, pyridyl, sulfonate. (se)

Compounds of formula M can be used directly, as, for example, in the case of sulfonic acid halides, sulfonic acid anhydrides, or others, for example, activated sulfonic acids (using sulfonic acid and dicyclohexylcarbonyldiimide, carbonyldiimidazole, etc.). (av)

The starting compounds are used, as a rule, in an equimolar ratio. Advantages can also be provided by the use of one or another component in an excess amount.

If necessary, it may be advantageous to carry out the reaction in the presence of a base. Reagents and its auxiliary base are used in equimolar amounts. A slight excess of auxiliary base, for example, from 1.5 to 3 molar equivalents per compound II, may provide advantages under certain conditions. Tertiary alkylamines, pyridine, alkali metal carbonates, such as sodium carbonate, potassium carbonate, and alkali metal hydrides, such as sodium hydride, preferably triethylamine and pyridine, are suitable as auxiliary bases. - c As a solvent, you can use, for example, chlorinated hydrocarbons, such as methylene chloride, 1,2-dichloroethane, and aromatic hydrocarbons, for example, toluene, xylene, chlorobenzene, a simple ether, such as diethyl ether, -» methyl-tert.-butyl ether, tetrahydrofuran, dioxane, polar, aprotic solvents such as acetonitrile, dimethylformamide, dimethylsulfoxide or esters such as acetic acid ester or mixtures thereof. -and As a rule, the reaction temperature is from 09C to the boiling point of the reaction mixture. Processing into b product can be carried out in a known way.

The pyrazoles of the formula I (where BK 72-H) used as starting materials are known and can be produced by known methods (for example, described in EP-A 240001 and in the publication of U. Rgaki Spet. 315, 383 (1973) "with the 050 method) .

Ф The derivatives of 3-(4,5-dihydroisoxazol-5-yl)-benzoic acid of the formula ІІ ni T І І : І К. value:

B", B? mean hydrogen, nitro, shalogen, cyano, C.-Svalkyl, C.-Svhaloalkyl, C.-Svalkoxy,

C.-Cohaloalkyloxy, C.-Cvalkylthio, C.--Cv-haloalkylthio, C--Cvalkylsulfinyl, C.--Cv-haloalkylsulfinyl,

C.-Cv-alkylsulfonyl or C.-Cv.haloalkylsulfonyl;

EZ hydrogen, halogen or S.-Svalkil; 27 hydrogen or S. Salkil; 25, 29 hydrogen, halogen, cyano, nitro, C--C; alkyl, C.-C;, alkoxy-C.--C; alkyl, di-(Ci4-C,-alkyl)- C.-Sulalkyl, di-(C1-Salkyl)-C4i-Sulalkyl, di-(C1-Salkyl)-amino-imino-C 4-Salkyl, hydroxy-imino-C1-Salkyl,

C.4-C-Alkoxyimino-C.-Alkyl, C.-C,-Alkoxycarbonyl-C -C.Alkyl, C.-C,-Alkylthio-C.-Alkyl,

C.i-C,-haloalkyl, C.-C.cyanoalkyl, C.i.-C.cycloalkyl, C.i-C; C-S-alkylthio, C-S-haloalkylthio, di-(Ci-C-alkyl)damino, SOKU, phenyl or benzyl, and both of the latter substituents may be partially or fully halogenated and/or may have from one to three such groups nitro, cyano, C--C;alkyl, C.--C.haloalkyl, C.i.-C.,.alkoxy or

C.i-C.halogenalkoxy; or 9 vide Co-Ce- and be vi and together form a Co-Cv-alkanedyl chain, which may be one to four times substituted by C.-C.-alkyl and/or may be interrupted by oxygen or optionally substituted

C.1-C.-alkyl nitrogen;

B means halogen, cyano, hydroxy, C--Salkyl, C--Cvhaloalkyl, C-C-C-Alkoxy, C-4-CvHalo-Alkoxy,

C.-Cvalkylthio, C.-Cvhaloalkylthio, C.-Cv-alkylsulfinyl, C.-Cvhalogenalkylsulfinyl, C.-Cv-alkylsulfonyl,

C.i.C.haloalkylsulfonyl, amino, C.-Ci.-alkylamino, di(C.i.-Ci.sub.6-alkyl)damino, di-(C.i.i.-C.i.-alkyloxy)methyl, hydroxyimino-C 1-Ci-dialkyl, C4- Sv-alkyoxmmino-C41-Cu alkyl or SOKZ;

BZ stands for hydrogen, C1-C1-alkyl, C1-C1-Shalogenalkyl, hydroxy, C1-C1-Alkoxy, C1-C1-C1-Alkoxy, C1-C1-C1-Alkoxy, C1-C1-Alkyl, C3-C1- alkenyloxy, C3-Svalkynyloxy or MAKUV 9; with

VE? means hydrogen or C, -C, alkyl; Gee)

VO means C.-C.alkyl; 275 means hydroxy or a residue removed by hydrolysis.

Examples of residues that can be removed by hydrolysis are alkoxy-, phenoxy-, alkylthio-, phenyl residues that may be optionally substituted, halides, heteryl residues bound by oxygen, amino residues, imino residues that are not can necessarily be substituted, etc. Preference is given to the halides (is) of 3-(4,5-dihydroisoxazol-5-yl)-benzoic acid of formula PI", where I is "halogen (- of formula II, where B is Y-halogen), o in (Ce) . E: 7 in p i- v i fi po " v shi s V . i? ta! -I where the substitutes from VE! to KE" have the given value for formula III and | means halogen, particularly chlorine or bromine.

Also desirable are 3-(4,5-dihydroisoxazol-5-yl)-benzoic acids of the formula Še (5 ШІ thi 5 - hydroxy), («c) Ш--« nn i Ж o («LUK (se) I- и Из - 4) Eye no Vo g sh ich) Yuyu vo ИИИЙ . . 1 7 . where the substituents from K' to K' have the values given for the formula HER.

Also desirable are complex esters of 3-(4,5-dihydroisoxazol-5-yl)-benzoic acid of the formula ПШ (- Ш, where

V'5-S.-Svalkoksi), b5

From V vk o ve

I: fi Ve v

E: eEz ,

III

75 where are the substitutes from EV! to B have the value given for the formula ХІ and I З means C.-C.-Alkoxy.

Especially preferred forms of execution of derivatives of 3-(4,5-dihydroisoxazol-5-yl)-benzoic acid of formula II with respect to substituents E1-K 7 correspond to 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles of formula I.

Benzoyl halides 3-(4,5-dihydroisoxazol-5-yl) of the formula PI" (where I is 1-SI, Vg) can be obtained in a known way by the interaction of 3-(4,5-dihydroisoxazol-5-yl)-benzoic acid of the formula PIPE with halogenation reagents such as thionyl chloride, thionyl bromide, phosgene, diphosgene, triphosgene, oxalyl chloride, oxalyl bromide 3-(4,5-dihydroisoxazol-5-yl)-benzoic acids of the formula Pe can be prepared in a known manner by acid or base hydrolysis from the corresponding of esters of formula II (where I is C-C-C-Alkoxy).

VE

59 o o va v y: ia ke

Ia Nuakhkoiuve nn nn shi in Vva no F 30 . and F

E: more | "in)

Ez (Se)

III III th-

Also, 3-(4,5-dihydroisoxazol-5-yl)-benzoic acids of the formula Ps can be obtained by the reaction of halogen-substituted compounds of the formula MI (where I" is a halogen), in particular, compounds of iodine or bromine, in the presence of a catalyst based on such a transition metal as palladium, nickel, cobalt or rhodium and bases with carbon monoxide and water under conditions of increased pressure.

Be sny iy i le shk SHE dv s Zdk o Ure y ch, Mn What and kasatuz ak Shi ay yy («v) ! : Mr. ! is), And here I am! 60th - there are still : ! at 65 SHY NI p sht h shk chan fri zhu, ry ap I SHT I: on ve YALTY

Further, the compounds of the formula MI can be converted using the Rosemund and Brown reaction into the corresponding nitriles of the formula MI! |see, for example, Ogo's publication. Have a drink Va P, 212 (19553) and convert them by subsequent saponification into compounds of formula PI. "The compounds of the formula MI, respectively MY, are also new, shi . p shcha i zd o. i so V y" i is

It is another pe dischona OY EV 70 ii Ж основ Ж Ж

And vv. at; . ; s he s". sh and gant ZE: and the substitutes here have the following meanings:

B", B? mean hydrogen, nitro, shalogen, cyano, C.-Svalkyl, C.-Svhaloalkyl, C.-Svalkoxy,

C.-C.halogenalkoxy, C.--Cvalkylthio, C.--Cv-halogenalkylthio, C--Cvalkylsulfinyl, C.-Cvhalogenalkylsulfinyl,

C.-Cv-alkylsulfonyl or C.-Cv.haloalkylsulfonyl;

EZ means hydrogen, halogen, or C-C alkyl;

VE? means hydrogen or S.-Sualkil; 25, 89 means hydrogen, halogen, cyano, nitro, C.--Sulalkyl, C.--C, alkoxy-C.-C,-alkyl, di-(C.i-C; alkoxy)- c

C.-Alkyl, di-(C4-C.alkyl)amino-C -C.-alkyl, di-(C.4-Alkyl)-amino-imino-C -Alkyl, Ge) hydroxy-imino-C 1- C; alkyl. C.-Cs-Sulfoxyimino-C-Sulfalkyl, cS.-C,-Alkoxycarbonyl-C 4-C.-Alkyl,

C.4-Salkylthio-C.--Salkyl, C.-C.halogenoalkyl, C.-C.cyanoalkyl, C.-C.cycloalkyl, C.-C; alkoxy,

C4-C/Alkoxy-C6-Alkoxy, C.i-Subhaloalkyloxy, C.-C;alkylthio, C.-C.haloalkylthio, di-(C.-C,-alkyl)amino,

СОВ8, phenyl or benzyl, and both of the latter substituents may be partially or fully halogenated and/or may have from one to three of the following groups: nitro, cyano, C--C;alkyl, C--C.haloalkyl, He »)

C.i-Slalkoxy or C.-C.halogenalkoxy; o or 25 kb together form a Co-C3-alkanedyl chain, which can be (Ce) substituted one to four times by C.-C.alkyl and/or may be interrupted by oxygen or optionally substituted by C.-C.alkyl nitrogen; m

B means halogen, cyano, hydroxy, C--Salkyl, C--Cvhaloalkyl, C-C-C-Alkoxy, C-4-CvHalo-Alkoxy,

S.-Swalkylthio, S.-Swhaloalkylthio, S.-Swalkylsulfinyl, S.--Swhaloalkylsulfinyl, S.--Swalkylsulfonyl,

C.i-Cvhaloalkylsulfonyl, amino, C.-Cvalkylamino, di-(Ci-Cv-alkyl)amino, di-(Ci-C; alkoxy)methyl, « hydroxyimino-C 1-Slalkyl, C4-Cv-alkoxyimino-C /-Slalkil or SOKU;

BZ means hydrogen, C.i-Slalkyl, C.i-Sahaloalkyl, hydroxy, C.i-C.-alkoxy, C.4-Slalkoxy-Co-C.alkoxy, - with C.-C haloalkoxy, C3-Sv -alkenyloxy, C3-Svalkynyloxy or MUK"; with E? hydrogen or C.-Salkyl;

VO S.-Sualkil;

AND

I" halogen. -i Special forms of the compound of the formula MI, respectively, MII, with respect to the substituents K 1.87 correspond to the substituents of 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles of the formula I.

Fo Complex esters of the formula IS, respectively, halogen compounds of the formula MI can be obtained with the help of 3-dipolar cycloaddition of nitrile oxides to the corresponding alkenes of the formula MIIII, respectively, IX. se) 4) ime) 60 b5 ia "WE: p -sh- Is you TO "how in! | what ! in i ' vi Ek sha MIZHYE osshoshi shoi go shodo shi 020. : t : H. rya a Sewing DV YN I "Ve t as

And x in av in; ! wai Where : o

Nitride oxides are obtained by known methods. Starting substances for this are, for example, aldoximes | see, for example, the publication of Noirep-UueuI| X5 p. 858 et seq or nitroalkanes |see, for example, (Se) publication Notsbrep-U/eu! E5/2, p. 1594 et seq.). The synthesis of compounds of the formula MI, respectively, IX, is known (cf., for example, UUCHO 98/50337, respectively, UMO 98/50366) or is carried out similarly to the methods described in these literary sources. | "in)

Preparation examples: c 4-(2-chloro-3-(3-methyl-4,5-dihydroisoxazol-5-yl)-4-methylsulfonyl-benzoyl/|-5-hydroxy-1-methyl-1H-pyrazole (compound 2.8) -

To a solution of 2.0 g (200 mmol) of 5-hydroxy-1-methylpyrazole and 3.3 g (24 mmol) of potassium carbonate in 30 ml of anhydrous dimethyloxyethane, a solution of b, 7 g (20 mmol) of 2-chloro-3- (3-methyl-4,5-dihydroisoxazol-5-yl)-4-methylsulfonyl-benzoyl chloride in 8Oml of dimethoxyethane. After stirring for 12 hours at room temperature, add another 8.2 g (ppmmol) of potassium carbonate and heat the reaction mixture under reflux for 6 hours. Then, after cooling, the reaction mixture with C is mixed with Tl water and extracted with methylene chloride. Then, the aqueous phase is set to a pH of 4 with "» 1095 hydrochloric acid and extracted several times with methylene chloride, and the pH value is adjusted. " After drying the organic phase and removing the solvent, 5.3 g (1Zmmol, 6790) of the target compound are obtained.

M.p.: 2215960, 4-(2-chloro-3-(3-methyl-4,5-dihydroisoxazol-5-yl)-4-methylsulfonyl-benzoyl/|-5-hydroxy-1-cyclopropyl-1H-pyra sh - zol (compound 2.36)

Ge" To a solution of 0.47g (Zmmol) of 5-hydroxy-1-cyclopropylpyrazole and 0.5g (3.bmmol) of potassium carbonate in Zbml of anhydrous dimethoxyethane, a solution of 1.0g (Zmmol) of 2 -chloro-3-(3-methyl-4,5-dihydroisoxazol-5-yl)-4-methylsulfonyl-benzoyl chloride in B5Oml of dimethoxyethane. After

After stirring for 12 hours at room temperature, add another 1.0 g (7.2 mmol) of potassium carbonate and heat the reaction mixture under reflux for 2 hours. After that, the reaction mixture is cooled and mixed with 10 ml of water and extracted with methylene chloride. Then the aqueous phase is adjusted to pH 4 with 1095 hydrochloric acid and extracted with methylene chloride. After drying the organic phase and removing the solvent, 0.8 g (1.8 mmol, 6395) of the target compound is obtained.

Tpl.: 22202.

ГФ) In Table 2, along with the above compounds, there are other compounds and derivatives of formula I, which were obtained or which can be obtained by a similar method 60 b5

Table 5

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Examples of the synthesis of some starting substances are given below.

To a solution of 2.6 g (1 mmol) of the complex methyl ether of 2,4-dichloro-3-ethenylbezoic acid and 1 g (1 mmol) of (o) 2,2-dimethylpropyunaldoxime in 100 ml of dichloroethane, add dropwise at room temperature 17 ml of a 1295% aqueous solution of sodium hypochlorite with vigorous stirring. After mixing each time for 5 minutes for 2 hours, another 0.5 g (bmol) of oxime and 1 ml of hypochlorite solution are added twice. The reaction mixture is stirred for another 12 hours at room temperature and then mixed with 35 ml of water. After extraction

Ф with dichloromethane, drying and removing the solvent, the residue is subjected to chromatography.

The yield is 1.5 g (4595 from theory) of yellow resin.

2-chloro-3-(33-ethoxycarbonyl-4,5-dihydroisoxazol-5-yl)-4-methylsulfonylbenzoic acid methyl ester

To a solution of 8.5 g (Zimmol) of the complex methyl ether of 2-chloro-3-ethenyl-4-methylsulfonylbenzoic (F) acid and 7.2 g (4 bmmol) of the complex ethyl ether of 2-chloro-2-oximinoacetic acid in 200 ml of dichloromethane g slowly b.4ml (4bmmol) of triethylamine is added dropwise at room temperature. After stirring every time for 2 hours, 3 portions of 4.8 g (Zimmol) of complex ethyl ether in 2-chloro-2-oxyaminoacetic acid and then 4.3 ml (Zimmol) of triethylamine are added. After stirring for another 12 hours at room temperature, the reaction mixture was mixed with 0.000 ml of water. After extraction with dichloroethane, drying and removal of the solvent, the residue was subjected to chromatography.

The yield is 5.7 g (47905 from theory) of transparent resin. 2-chloro-3-(3-methyl-4,5-dihydroisoxazol-5-yl)-4-methylsulfonylbenzoic acid a) complex methyl ester of 2-chloro-3 (3-methyl-4,5-dihydroisoxazol-5-yl )-4-methylsulfonylbenzoic acid б5 и и ; I

To a solution of 40 g (145 mmol) of the complex methyl ester of 2-chloro-3-ethenyl-4-methylsulfonylbenzoic acid and 50 g (220 mmol) of di-tert.-butyl carbonate in ZbOOml of acetonitrile, add 4-dimethylaminopyridine on the tip of a knife and then slowly add 50 g dropwise. (b40mmol) of nitroethane. After stirring for 12 hours at room temperature, another 2.8 g (145 mmol) of di-tert.-butyl carbonate and 22.9 g (290 mmol) of nitroethane were added. After stirring for another 12 hours, the solvent is distilled off and the residue is digested with ethyl acetate. After suction, 32.1 g of the target compound remains. After removal of the solvent and subsequent chromatography, another 6.3 g of the target product is obtained from the mother liquor.

The output is 39.4g (8295 from theory).

Melting point: 17596, 70 b) 2-chloro-3-(3-methyl-4,5-dihydroisoxazol-5-yl)-4-methylsulfonylbenzoic acid

To a solution of 38.4 g (11 mmol) of the complex methyl ester of 2-chloro-3-(3-methyl-45-dihydroisoxazol-5-yl)-4-methylsulfonylbenzoic acid in 400 Oml of methanol and 40 Oml of tetrahydrofuran, add 69.4 g (174 mmol) 1096 of sodium alkali. The reaction mixture is stirred for 12 hours at room temperature, the solvent volume is reduced by half and poured into 1 liter of water. With the help of 1095 hydrochloric acid, set the pH value to 1 and suck off the formed sediment.

The output is 35.2g (9695 from theory).

M.p.: 222096, 2-methyl-3-(3-methyl-4,5-dihydroisoxazol-5-yl)-4-methylsulfonylbenzoic acid a) 2-methyl-3-(3-methyl-4,5-dihydroisoxazol- 5-yl)-4-methylsulfonylbromobenzene

To a solution of 13.bg (5 mmol) of 2-methyl-33-ethenyl-4-methylsulfonylbromobenzene and 16.7 g (74 mmol) of di-tert.-butyl carbonate in 1700 ml of acetonitrile, 4-dimethylaminopyridine is added on the tip of a knife, and then 17 is slowly added dropwise. 9 g (229 mmol) of nitroethane. After stirring for 6 hours at room temperature, add another 11.1 g (bbmmol) of di-tert.-butyl carbonate and 7.8 g (10 mmol) of nitroethane and stir at room temperature for 12 hours. After removal of the solvent, the residue is subjected to chromatography. Ha

The yield is 6.4g (3895 from theory). b) 2-methyl-3-(3-methyl-4,5-dihydroisoxazol-5-yl)-4-methylsulfonylbenzoic acid i) 6.4 g (19 mmol) 2-methyl-3-(3-methyl-4,5 -dihydroisoxazol-5-yl)-4-methylsulfonylbromobenzene is dissolved in bb5ml of toluene and ZOml of water and mixed with 240ml (mol) of palladium acetate, 1.1g (Ammol) of tricyclohexylphosphane, 810ml (19mmol) of lithium chloride and 5.4ml (Zvmmol) of triethylamine . The resulting solution is stirred in an autoclave for 3 hours at 1402 under a carbon monoxide pressure of 20 bar. After cooling and depressurization, the insoluble components are filtered and the phases are separated. The organic phase is extracted twice with water containing triethylamine. Then, the collected aqueous phases are adjusted with the help of 1095 hydrochloric acid to a pH value of 1 o and the resulting precipitate is filtered. Output is 2.5g (44965 from theory)

Tel.: 199-20526. oh

Table C below shows, along with the compounds described above, other derivatives of 3-(4,5-dihydroisoxazol-5-yl)-benzoic acid of formula I (where the substituents BK? and B? mean hydrogen), which are obtained or which can be obtained by similar way

Tabpytsa in "

And ev di t | SCHI SCHI in i- From yen. 7 of

Fa 68 (66800 vk 0010170 v 30133130 fe

For

Fe (in Oveyn at 06000000

F with Hordoy Nov. YOU. ot oh |Va zlo (B odvest, (NO But bbbetiien Ya.

Or vra vo b5 z re 3 42020001 fbeenyanv vyv |v es | ns 00 br va v. (660 (e bno 00066001 for ev 66111111 and i ve 63 01111110 3-(4,5-dihydroisoxazol-5-yl)/benzoylpyrazoles of the formula !/ and their salts applicable in agriculture can be used both in the form of a mixture of isomers and in in the form of pure isomers in the function of herbicides.

Herbicides containing compounds of formula I are well suited for combating the growth of plants on areas occupied by uncultivated plants, in particular, at high application rates. On crops such as wheat, rice, corn, soybeans, and cotton, they act against weeds and harmful grasses, with virtually no damage to cultivated plants. This effect takes place, first of all, at low consumption rates.

Depending on the appropriate method of processing the compound of formula I, accordingly, the herbicides containing them can be used on a whole range of crops to combat unwanted vegetation. At the same time d) it is worth mentioning as an example the following cultures:

AIyit sera, Apapaz sotoziv, Agaspiz purodaea, Azragadivz oiiisipaiz, Veba mutzdapz zres. Aizvita, Vega mucIdape adult. mountain, Vgazzisa Paris mag. parivz, Vgazzisa paris mag parobrgazzisa, Vgavzvisa gara mag. viimevipv,

Satetsca zipepziz, Sapypativs (psiopy5, Sagua Shipotepvziv, Sygivz top, Siygiv vipepziz, SoPea agabisa ise) (SoPea saperpoga SoPea Pprepsa), Sisytiv zaymiv, Supodop dasiyup, YuOatsysivz sagoia, EIIiaeiv diipeepviv, b

Егадапа мевзса, Сіусіпле тах, Совзвурішт ПігешшШт, (бовзвурішт агрогенит, Соввурішт Пеграсецт, Соззурішт мййопит), Неїїапіпиз аппииз, Немеа Бгавзіпепвзі5, Ногдешт мцідаге, Нитиїча Іюршшв5, Іротоеа бБаїайаз, дидіапв о гедіа, еп сиїтапв, Сіпит ивнакззвітит, Гусорегвісоп Іусорегвісит, Маїйз зрес ., Mapipoi ezscepia, Medisado «(o zaina, Myza zres., Misoyapa (arasit (M.giviisa), Oiea epgoraea, Ogula zaina, RiazeoYiz Ishpai5, RIiazeoiYiiv5

Zo utsIdapz Risea abriev, Rapiz vres., Rizvit zaymit, Rhypyv amisht, Rhypyv regvisa, Rugyv sottipiv, Kirevz - zuievige, Kisipliz sottipiz, sassphagite oiPistagit, ZesaIe segeaie, Zoyapyt (shregosite, Zogopyt bBisoiog (see ucIdage), Tpeobgota sasao, Tiopyt rgahepze, Tpiisit aeviimit, Tpiisit digit, Misia Tara, Mikiz mipi'tega | 7ea tauv.

In addition, compounds of the formula | can be used on crops that, as a result of their selection, including genetic engineering methods, have acquired resistance to the action of herbicides.

Compounds of formula I, respectively, herbicides containing them, can be used, for example, in the form of directly sprayed aqueous solutions, suspension powders, and also | highly concentrated aqueous, "» oily or other suspensions or dispersions, emulsions, oily dispersions, pastes, dusting agents, "dispersing agents or granules, and they are applied by spraying, fine-drop spraying, dusting, spreading or watering. The processing technology and the forms used depend on the purpose of application, but in all cases it must be as thin and uniform as possible. distribution of claimed active substances.

Ф Herbicides contain such that has herbicidal activity, the amount of at least one compound of the formula

It or one applicable in agriculture salts of formula I! and auxiliary agents usual for the preparation of compositions of plant protection products.

Ge) 50 In the function of inert auxiliary agents, it is possible to use mainly fractions of mineral oils from medium to high boiling points, such as kerosene or diesel oil, then oil from coal tar, and m, also oils of vegetable or animal origin, aliphatic, cyclic or aromatic hydrocarbons such as paraffin, tetrahydronaphthalene, alkylated naphthalenes or their derivatives, alkylated benzenes or their derivatives, alcohols such as methanol, ethanol, propanol, butanol, cyclohexanol, ketones such as cyclohexanone or highly polar solvents such as amines, such as M-methylpyrrolidone and water.

GF) Aqueous compositions can be prepared from emulsion concentrates, suspensions, pastes, wettable powders, or granules that are dispersed in water by adding water. To obtain emulsions, pastes or oil dispersions, 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles can be homogenized in water both by themselves and in the form dissolved in oil or in a solvent, with the help of wetting agents such as stick, 60 dispersing or emulsifying additives. Concentrates suitable for diluting in water can also be made, consisting of an active ingredient, a wetting, tacking or emulsifying agent and, if necessary, a solvent or oil.

In the function of surface-active substances (auxiliary agents), it is possible to use salts of alkali, alkaline earth metals, ammonium salts of aromatic sulfonic acids, for example, lignin-, phenol-, naphthalene- and bo-dibutylnaphthalene sulfonic acids, as well as salts of fatty acids, alkyl and alkylaryl sulfonates, alkyl sulfates,

lauryl sulfoethers, sulfates of fatty alcohols, as well as salts of sulfated hexanols, heptanols, and octadecanols, as well as glycol ethers of fatty alcohols, condensation products of sulfonated naphthalene and its derivatives with formaldehyde, condensation products of naphthalene, respectively, naphthalene-sulfonic acid with phenol and formaldehyde, polyoxyenoctylphenol ether, ethoxylated isooctylphenol, octylphenol or nonylphenol, alkylphenylpolyglycol ether, tributylphenylpolyglycol ether, alkylaryl polyether alcohols, isotridecyl alcohol, condensates of ethylene oxides of fatty alcohols, ethoxylated castor oil, simple polyoxyethylene alkyl ether or polyglycol ether acetate of lauryl alcohols, sorbitol ester, spent lignin-alkali sulfate or methylcellulose. 70 Powdered, scattered and sprayed agents can be obtained by mixing or co-grinding the active substances with a solid filler.

Granulate, for example, impregnated, shell and homogenous granulate, can be made by binding active substances with solid fillers. Solid fillers are mineral earths such as silicic acids, silicates, talc, kaolin, limestone, lime, chalk, bolus, loess, clay, dolomite, diatomaceous earth, calcium sulfate and magnesium sulfate, magnesium oxide, crushed plastics, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea and vegetable products such as grain flour, tree bark flour, wood flour and nut shell flour, cellulose powder and other fillers.

The concentration of compounds of formula I in ready-to-use compositions can vary widely.

The compositions generally contain from 0.001 to 0.8% by weight, preferably from 0.01 to 0.9% by weight of at least one active ingredient. Active substances are used with purity from 9095 to 100905, preferably from 9595 to 10095 (according to the NMR spectrum).

The following examples explain the preparation of such compositions:

I. 20 parts by weight of the compound Mg. 2.7 is dissolved in a mixture consisting of 80 parts by weight of alkylated benzene, 10 parts by weight of the addition product of 8-1 moles of ethylene oxide to a mole of M-oleic acid monoethanolamide, 5 parts by weight of the calcium salt of dodecylbenzene-sulfonic acid and 5 parts by weight of the addition product of 4O0 moles of ethylene oxide to Tmol of castor oil. By pouring and finely distributing the solution in 10,000 Ovag. parts of water, an aqueous dispersion is obtained, which contains 0.02 wt. 90 of the active substance. Ge zo PL. 20 parts by weight of the compound Mg. 2.7 is dissolved in a mixture consisting of 40 parts by weight of cyclohexanone, 30 parts by weight of isobutanol, 20 parts by weight of the addition product of 7 moles of ethylene oxide to 1 mole of isooctylphenol and 10 parts by weight of the addition product of 4 moles of ethylene oxide to thymol of castor oil. By pouring and finely dividing the solution in 100,000 parts by weight of water, an aqueous suspension containing 0.02 mass.95 of the active substance is obtained. co

Sh. 20 parts by weight of the active substance Mg. 2.7 is dissolved in a mixture consisting of 25 parts by weight of cyclohexanone, 65 parts by weight of a fraction of mineral oil with a boiling point from 210 to 2802 and 10 parts by weight of the product of the addition of 4 moles of ethylene oxide to one mole of castor oil. By infusion and fine distribution in 100,000 parts by weight of water, an aqueous suspension is obtained, which contains 0.02 mass.9o of the active substance. "

IM. 20 parts by weight of the active substance Mg. 2.7 mix well with 2 parts by weight of sodium salt ke) with diisobutylnaphthalene sulfonic acid. 17 parts by weight of the sodium salt of ligninsulfonic acid from spent and sulfite alkali and 60 parts by weight of powdered silica gel and everything is ground in a hammer mill. "" Thanks to the fine distribution of the mixture in 20,000 parts by weight of water, a solution for spraying is obtained, containing 0.95% of the active substance.

M. From the weight fraction of the active substance Mg. 2.7 is mixed with 97 parts by weight of fine kaolin. In the following way, a spray containing 90% of the active substance is obtained.

E. 20 parts by weight of the active substance Mg. 2.7 is well mixed with 2 parts by weight of calcium salt

Fo dodecylbenzenesulfonic acid, 8 parts by weight of polyglycol ether of fatty alcohols, 2 parts by weight of sodium salt of the condensation product of phenol-urea-formaldehyde and 68 parts by weight of paraffin 5r Mineral oil. A stable oil dispersion is obtained. about MII. 1 part by weight of compound 2.7 is dissolved in a mixture consisting of 70 parts by weight of cyclohexanone,

F 20 parts by weight of ethoxylated isooctylphenol and 10 parts by weight of ethoxylated castor oil.

A stable emulsion concentrate is obtained.

E. 1 part by weight of compound 2.7 is dissolved in a mixture consisting of 80 parts by weight of cyclohexanone 5B and 20 parts by weight of the Mayo product! EM 31 (nonionic emulsifier based on ethoxylated castor oil).

A stable emulsion concentrate is obtained. (F, Treatment with active substances of formula I, respectively, with herbicides, can be carried out at the pre-emergence or post-emergence stage. If the active substances have reduced compatibility with some types of cultivated plants, then such a technology of treatment with the help of sprayers can be used, so that herbicides, if possible did not fall on the leaves of sensitive cultivated plants, while the active substance would fall on the leaves of undesirable plants growing among them, or on open areas of the soil (directional spraying method, respectively, tape spraying method).

Rates of consumption of compounds of the formula | are, depending on the purpose of application, season, target plant and growth stage, from 00.001 to 3.0, preferably from 0.01 to 1.Okg/ha of active substance. 65 To expand the spectrum of action and to obtain a synergistic effect of 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazole of the formula | can be mixed with numerous other herbicidal or growth-regulating groups of active substances and applied at the same time. As co-components of the mixture, the following can be used, for example: 1,2,4-thiadiazoles, 1,3,4-thiadiazoles, amides, aminophosphoric acid and its derivatives, aminotriazoles, anilides, aryloxy-/heteroaryloxyalkene carboxylic acid and its derivatives, gasoline

Acid and its derivatives, benzothiadiazinones, 2-(hetaroyl/aroyl)-1,3-cyclohexanediones, hetarylaryl ketones, benzylisoxazolidinones, meta-C3-phenyl derivatives, carbamates, quinolinecarboxylic acid and its derivatives, chloroacetanilides, cyclohexanoxime ether derivatives, diazines, dichloropropionic acid and its derivatives, dihydrobenzofurans, dihydrofuran-Z-ones, dinitroanilines, dinitrophenols, diphenyl ethers, dipyridyls, halocarbonic acid and its derivatives, urea, Z-phenyluracils, imidazoles, imidazolinones, 70 M-phenyl-3,4,5,6- tetrahydrophthalimides, oxadiazoles, oxiranes, phenols, esters of aryloxy- and heteroaryloxyphenoxypropionic acids, phenylacetic acid and its derivatives, phenylpropionic acid and its derivatives, pyrazoles, phenylpyrazoles, pyridazines, pyridinecarboxylic acid and its derivatives, pyrimidyl ethers, sulfonamides, sulfonylureas, triazines, triazinones, triazolinones, triazolecarboxamides, uracils.

In addition, it may be appropriate to mix compounds of the formula | by themselves or in combination with other herbicides, with other means of plant protection, and their simultaneous application, for example, with means of combating pests or phytopathogenic fungi or bacteria. Mixtures of these compounds with solutions of mineral salts used to compensate for deficiencies in nutrients and trace elements are also of interest. Non-phytotoxic oils and oil concentrates can be added.

Application examples

The herbicidal activity of 3-(4,5-dihydroisoxazol-5-yl)-benzoylpyrazoles of the formula !/ can be demonstrated by conducting experiments in a greenhouse.

The function of greenhouse containers was performed by plastic miners with clay sand with approx. 3.095 humus as a substrate. The seeds of experimental plants were sown with distribution by varieties.

During preemergence treatment, active substances suspended or emulsified in water were applied directly with 2g5 After sowing using nozzles that provide fine spraying. The pots were lightly sprinkled to promote germination and growth, and then covered with clear plastic covers until i) the plants were established. Such a coating contributes to the uniform germination of experimental plants that have not yet been exposed to active substances. During the post-emergence treatment, the experimental plants, depending on the exterior, were grown to a height of 3 to 15 cm and then treated with Gezo active substances suspended or emulsified in water. For this purpose, experimental plants were sown and grown in the same pots or they were germinated separately until sprouts appeared and a few days before processing, they were transplanted into experiment pots/ Me

The consumption rate during post-emergence treatment was 125, respectively, 62.5 g/ha of active substance. at

Depending on their species, the plants were kept at temperatures from 10 to 259C, respectively from 20 to 3596.

The duration of the tests was from 2 to 4 weeks. During this time, the plants were carefully cared for and their reaction to each of the individual treatments was evaluated. uh-

The evaluation was carried out on a scale from 0 to 100. Here, "100" means that the plants did not descend, respectively, complete destruction of at least the aerial parts was observed, while 0 means no damage or normal growth.

The plants used for experiments in the greenhouse were selected from the following species: "- p

I" 15 - (2) At consumption rates of 125, respectively 62.5 g/ha, compound 2.7 in post-emergence treatment showed a very good effect against the above-mentioned phytopathogenic fungi and tolerance on gorse.

Known from MO 97/41118, the control compound A (compound 20 from Table 1) at the same rates of consumption (se) leads to damage to the gorse, as well as to weaker herbicidal activity against the listed harmful plants,

Claims (10)

The formula of the invention and and and that, 1. 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles of the formula Ф) ав от име) || ee in Gnij ve 60 izh ez where "B" means halogen, Si-Svalkyl, Si1-Svalcoxy; B - halogen, C-Svalkyl, C--Svalkylsulfonyl; 23-85 - hydrogen; B - C-C alkyl, C-C alkyl, di-(Ci-Slalkoxy)methyl or SOKZ; в8- hydroxy, C-C, alkoxy; B" means a pyrazole of the formula I! c, GG IM - MI o И 2, where 72 means hydrogen, C3-C.alkynyl, thienylmethyl, phenyl, benzyl, phenylcarbonyl, phenylsulfonyl or phenylcarbonylmethyl, and the phenyl residue of the last n Some of the substituents can be substituted by C-C alkyl or halogen; BZ - C-C alkyl, C-C alkyl or C 3-C cycloalkyl; B" - hydrogen, C 4 alkyl or C 3-C cycloalkyl; as well as their salts applicable in agriculture. 2. 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles of the formula | according to claim 1, where 272 means phenyl, which may be partially or fully halogenated or may have from one to three S.-Slalk groups. high school 3. 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles of the formula | according to claim 1, where "B" means benzyl, and the phenyl residue can be partially or fully halogenated or can have from one to three C.4-C;alkyl groups. 4. 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles of formula I according to claim 1, where B? means hydrogen. 5. 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles of the formula ПИ |se) IR Kk, and ог Ф t "c) ВЕ Ге в (Се) Е2 ич- Shk where КЕ" means hydroxy, halogen or oxymethyl and "v"-v and 1-4 have the meanings given in paragraphs. 6. Compounds of the formula MI - t. s to t . n » Ii and I in 5 -I E: F re o de B7- B" have the values given in claims 1-4; c I means halogen. Ф 7. Means for plant protection, which contains a herbicidally active amount of at least one 3-(4,5-dihydroisoxazol-5-yl)/benzoylpyrazole of the formula | or one agriculturally applicable salt of the compound of formula I according to any of claims 1-4 and auxiliary agents usual for such a means. 8. The method of obtaining the agent according to claim 7, which is characterized by the fact that the herbicidally active amount of at least one /3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazole of the formula | or one applicable in the rural F, farm salt compound of the formula | according to any of claims 1-4 are mixed with auxiliary agents usual for such a means. 9. A method of combating the growth of unwanted plants, which differs in that the herbicidally active amount of at least one 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazole of the formula | or one agriculturally applicable salt of the compound of formula I! according to any of claims 1-4 affect plants, their growing space and/or seeds. 10. Application of 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazoles of the formula | and their agriculturally applicable salts according to any of claims 1-4 as herbicides. b5