UA74043C2 - Fungicidal mixture and a method of controlling phytopathogenic fungi - Google Patents

Abstract

The invention relates to fungicidal mixtures, containing a) a benzophenone of formula (I), b) a carbamate of formula (II) and c) an azole derivative of formula (??????), in synergistically effective amounts and a method for the treatment of noxious fungi with mixtures of compounds (I), (II) and (??????). The active substances of formula (??), (????) and (III) are defined in the description.

Description

Sha: common name: epoxiconazole, ER-A 196 038,

SABAM | 106325-08-01; I Pr: common name: metconazole, Rhos. Hg. Stor Rgoi. Sopi - Reziv Oiv., 5-4, 419 (1992), SAB VAM (125116-23-6); Che: common name: propiconazole, SV-A 1,522,657,

SAB5 AM (60207-90-11;

Nia: common name: tebuconazole, ER-A 40345,

SABAM |(107534-96-3|; Che: OE-AT98 29 075.

Double mixtures of benzophenones of formula I with azole derivatives of formula III are known from EP-A 1,023,834.

Dual mixtures containing carbamates of formula II and azole derivatives of formula II are known from EP-A 900 021.

Possible synergistic action between substituted benzophenones of formula I! and carbamates of formula II (see table II) is known from UUO-A 00/76317. However, synergistic action is not proven in this source. Taking into account the reduction of consumption rates and the improvement of the spectrum of action of known compounds I, ІІ and Іі, as well as known double mixtures, the task of the invention is to create mixtures that, with small total amounts of consumption, provide an increased effect against phytopathogenic fungi (synergistic mixtures).

In accordance with this, the above mixtures were developed. In addition, it was developed that with the simultaneous, namely joint or separate application of compounds I, II and I or with the application of compounds

І, M and І consistently better fight against phytopathogenic fungi than these compounds alone or separate double mixtures.

The following compounds of the formula | are partners in the mix, and the individual benefits are meant both individually and in combination.

Compounds I are preferred in which B' represents chlorine, methoxy, acetoxy or hydroxy and, in particular, compounds in which B' represents methoxy, acetoxy or hydroxy are preferred. Compounds in which B! stands for methoxy.

According to the invention, compounds of formula I are preferred, in which B? denotes chlorine or methyl. Particularly preferred are the compounds of formula I, in which B? denotes methyl.

In addition, the compounds of formula I are preferred, in which BZ represents hydrogen, methyl, chlorine or bromine, and particularly preferably hydrogen, chlorine or bromine.

Along with this, the compounds of the formula I, in which B? denotes CgC4-alkyl or benzyl, and the phenyl part of the benzyl residue may have halogen or methyl substituents. Particularly preferred are the compounds of formula I, in which B" denotes CCa-alkyl and, preferably, methyl.

Next, the compounds of formula I are preferred, in which the substituents B', B, B3 and B" have the following values:

IN! denotes methoxy, acetoxy or hydroxy;

B2 denotes methyl;

VZ denotes hydrogen, chlorine or bromine and

B denotes C04-alkyl.

Along with this, the compounds of the formula !/, in which the substituents have the values given in the table below, are particularly preferable: in Gi sia. 3 with mA

And I

In wasp with

The table of her pi i i i nn o a zhk

N and N N I

N N N I ' kish: mouse tires

C | BUT fan level

Pt me Di and PI ie to her,

N N N S destiny

PM Purpose | PI! : and eat

Nekiny forging OV OK PES about PD en

HNE Methoxy | n | n 1 hMetazfeny nn on nn

NAME Tags | and I V | Label: ! | N

M 0 Metaxy s I VE N n-Propiy H i I | and mornings nn nn V

SM Metoksya s N Ve I n-Butyp N

N i N ' N ra Metokoi s I V | Gasoline!

GNN KO on pi nn

IB Metoksya Fo Ve Zartorobenanya I

P molting and ! With the goal of MvyailoO | m Mataya gne Mn ACTS PI pi

SE etno Met og Metii sf pn i pa ov what Goal 1 Goals n v-tiropil N fund ryaninnntnnnfenyinnnnn feny i-th Goal 1 Goal: n v-Butyp N

VO PI An kih pn

CAT: Tags ro Metgya | tsi Benayl i i I i i tru kati fe et etno detntnttenttntit

AND? And about Metonsy | Metyp | n io bFtrobenzite

N N I 1 I N NOOKYNI and in MN k

Hay Mety Ttvyai | Pe T fetorobenayat i and nn po p Pa

MA ОЙ oMetoeey ro oMetto M 1000 a"Fluorophenyl

N' | Y N uetddttttttiit tannia rn

PO RBOr about Metonea Ro Meta | n 100 2-Metyphenium 1 |! N and

DV ZAD I i Che MI ni ia

GEO Goal Goal 10 7 Z-Metipphenius

And I and I nn nin la 1 2U | Methoxy oi 0 Metkya I n 00 4Mechhipephrenium ; 4 and Y sha :RB28 1 Methods 10 May I Vi I Methyl

I SW MON Z MON 129 ro Mezhi oi Meitiya ve N k-Prayil

IR oMetozhoe 1 Met V ! v-Butyl nn r Y Metohei oi oo Metyaia | Wu N. Benanl N

And! N N N o po - ND COCO i i niks

NeKUu Labels of Metshl o: BE KO aFfluorobenziy and already PA her | Ancetokse ro Mep | n 17 Metyp and mya | Acetoys 0 Met p now not and H! |! : the language of the Poles of the Poles, Vrov Vv Opor Non nn nn 135 | Objectives of obtsetokuov VE and Metil and p p wai Go Plrokon oi Metsya V ! Throw N to the sphere of dynasties! s, hairdryer 832 Pdrozhi ro Mel ! ia I Metkya: i-38 and Pdroysi oi Mechypy | Ve | Sam I Z Pivaloiloyut!: Methyl | n | Methyl i i N N aa in va OO 140 rf pPivayasiokoy: 0 Methyl s Methyl:

I; Pivzhloilaksy 0 Metyp Ve KMetyy and 1421 si N s | n I Metiya N va a : a 1 nn N yaPropya N i N ! N N there tt aa nuti! tya soi rr noi Bvnzyp ! ' i N I i i re nin t nin pon wn porn nn pa nin nn re | Ko: Gu N M 1 ffFtorosyenznya shi an nn pi MOH rn | Oh! (ki H n 1 ZeFtorobenzip

N N ' N ri s N z : Gv 1 bartorofenya i i i i io | and N Go! n 10 F Metipphenius (not V pi

Ha | si RON Methiphenyu p nina Mi VA MA ry TT si : a i n 1 Methiphene ' 1 N N Y N

PUBLICATION OF MRS

NIH DAN NK V V NN,

That's in Benzlo! pen nn nn p pyv pi min

PT SHORTS fetorobeyaaya

SBU Omeyai 00 Mezhi NO Metya

I N N N N ryaa! Metmya ro oMmetya vn N ya Proty i

And Metyp o ro Mezhd: V i sh-utiv.

Hn Z 40400 1-8 Metya oo Metya | Kk - Denzip Y

N: N! and sun also tya so

GMO Meten Her Metmya | n 2-fluorobenany meal tn rent 1621 oMemp oi Mezha yn Zartorebenny

Tory -82ZV--- 8 1 Mep 10 May ! and arenas

RB8AO 0 Metny and Motyp i GO bMetmafenii (1:

N Y ! NIKY | Pas:

GB Mel 1 Border 100010 zMefafenya

NNNNNNNNIV PO p. and piinnnttannnnnn

TV be 10 Metnya NO zMetmpfen and | See (ZP R «o 2 RA p methyl i Metyp I : Metyp i sn N POCOKO PA in 18800 Mark | Mety V I n-Propiy i

EN Goals about | Met vuh tt

Until now PON In

KM Metiy Metyp in Benzyl and

MY Methyl | Methyl B: : F-Fluorobenania

Formula 11-x represents carbamates in which the combination of substituents corresponds to one of the lines of the table below:

The table of іі ш пініішшш ж пышшшшшШяяйнный пашу

up to now,

GO | as well as pd ; a-! pi zhi nin in

N N and guilty and ZV and: and the child pa | av and roChnooo. ana

OM 3-sV, plans zu, i

OO MY nie a KE 2; and in DAE; tt pi i mo pn I a ma, t vka a ana ana anna a a a a a

WHAT | VANS

As components of B), compounds of formula II, in which A represents fluorine, chlorine, methyl or trifluoromethyl, are preferred.

Compounds of formula II in which A is in the para position are equally preferred. These compounds are described by formula Ia:

g yav, -K- 1 y, tta yo zasn

The best are fungicidal mixtures that contain as components a) one of compounds 1-33, 1-35, 1-42, 1-44, 1-46, 1-60 or preferably 1-18, 1-28, I-37 , as components B) one of the compounds: 1I-3, 11-12, 11-17 or preferably 1-6 or as components c) compounds PI-a.

Compounds II due to the basic nature of nitrogen atoms contained in them can form salts or addition products with inorganic or organic acids or metal ions.

Examples of inorganic acids are hydrohalic acids such as hydrofluoric acid, hydrochloric acid, hydrobromic acid and hydroiodic acid, carbonic acid, sulfuric acid, phosphoric and nitric acids.

Suitable organic acids are, for example, formic acid and alkanoic acids such as acetic, trifluoroacetic, trichloroacetic and propionic acids, as well as glycolic acid, lactic acid, succinic acid, p-toluenesulfonic acid, salicylic acid, p-aminosalicylic acid, 2- phenoxybenzoic acid, 2-acetoxybenzoic acid.

As metal ions, in particular, ions of elements from the first to eighth side groups are suitable, primarily chromium, manganese, iron, cobalt, nickel, copper, zinc, and along with the second group, primarily calcium and magnesium, the third and fourth main groups, in particular, aluminum , tin and lead. Metals can be taken with different valence assigned by him.

Pure active substances of formulas I, I and II are mainly used for mixtures, to which other active substances against phytopathogenic fungi or against pests, such as insects, namely those that weave webs or nematodes, as well as herbicides and those that regulate growth, active substances or fertilizers.

Mixtures of compounds of the formulas I, II and II, respectively, compounds of the formulas I, II and PI are used simultaneously, together or separately, while providing an excellent effect against a wide range of phytopathogenic fungi, in particular, from the class of acomycetes, basidiomycetes, phycomycetes and deuteromycetes. They are effective systemically and can be used as foliar and soil fungicides.

They are of particular importance in the fight against many fungi on various cultivated plants, such as cotton, vegetable crops (for example, cucumber plants, legumes, tomatoes, potatoes and pumpkins), barley, sod, bananas, coffee, corn, fruit plants, rice, rye, soybeans, grapes, wheat, ornamental plants, sugar cane, as well as on many seeds.

They are especially suitable for combating the following phytopathogenic fungi: Vishtega dgatipiv (true powdery mildew) on cereals, Eguzirne sispogaseagit and 5rpaegoipesa Shiidipea on pumpkin crops, Rhodozrpaega Ieisoyispa on apple trees, Osippschia pesaiog on grapevines, species of Ryssipia on cereals, species of Apigosiopia,a on cotton rice and turf, species of OzShado on cereals and sugar cane,

Mepishgia ipayedptsaiiiz (scab) on apple trees, species of NeItipipoprogpts on cereals, Beriopa podogyt on wheat,

Voiguiiv sipega (mould-like gray rot) on strawberries, vegetables, ornamental plants and vines, Segsozroga agaspidisoia on earthen field, Rheidosegsozrogeiia pegroipispoides on wheat and barley,

Rugissaga ogugae on rice, Rpuyurntoga ipgeviap5 on potatoes and tomatoes, Riaztoraga mysoia on vines, species of Reepdoregopozroga on hops and cucumbers, species of AIegpapya on vegetables and fruits, species

Musozrpaigeia on bananas, as well as Rizagyt and Mepisiisht species.

In addition, they are used to protect materials (for example, to protect wood), for example against Raesiyutusez magiotsi.

Compounds of formulas I, II and I can be applied simultaneously, namely together or separately, or sequentially, and the sequence in separate processing generally does not affect the success of the action.

In mixtures, compounds of formulas I, II and II are usually used in such a way that the ratio in the mixture of compounds I and II, I and II, as well as II and II is from 20:1 to 1:20, and in particular, from 10:1 to 1:10 .

Consumption rates of mixtures according to the invention are, primarily on agricultural crops, depending on the desired effect, from 0.01 to 8 kg/ha, preferably from 0.1 to 5 kg/ha, in particular from 0.1 to 3.0 kg/ha.

The rates of consumption of compounds I are from 0.05 to 5 kg/ha, preferably from 0.08 to 3 kg/ha, in particular from 0.06 to 2.0 kg/ha.

Consumption rates for compounds II are from 0.005 to 3 kg/ha, preferably from 0.02 to 2 kg/ha, in particular, from 0.04 to 1.0 kg/ha.

Consumption rates for compounds I are from 0.01 to 2 kg/ha, preferably from 0.05 to 1 kg/ha.

When processing seed grain, in general, consumption rates of the mixture are used from 0.001 to 250 g/kg of seed grain, preferably from 0.01 to 100 g/kg, in particular, from 0.01 to 50 g/kg.

When combating phytopathogenic fungi, plants are treated separately or jointly with compounds I, II and, if necessary, I or mixtures of compounds I! and II and if necessary I, by spraying or dusting of seeds, plants or soil before sowing or after sowing of plants or before or after germination of plants.

Fungicidal synergistic mixtures according to the invention, respectively compounds I, II and, if necessary, II, can be prepared, for example, in the form of solutions, powders or suspensions intended for direct spraying, or in the form of highly concentrated aqueous, oily or any other suspensions, dispersions , emulsions, oil dispersions, pastes, dusting preparations, dusting preparations or granules and can be applied by spraying, fine-drop spraying, dusting, dusting or watering. The forms of use depend on the purpose of application, but in all cases they must ensure the most thin and uniform distribution of the mixtures according to the invention.

Preparative forms are obtained in a known manner, for example, by adding solvents and/or fillers. Inert additives, such as emulsifiers or dispersants, are usually added to the preparation forms.

Suitable surfactants are alkaline, alkaline earth, ammonium salts of aromatic sulfonic acids, for example, lignin sulfonic acids, phenol sulfonic acids, naphthalene sulfonic acids, dibutyl naphthalene sulfonic acids, as well as fatty acids, alkyl sulfonates and alkylaryl sulfonates, alkyl sulfates, lauryl ether sulfates, and sulfates of fatty alcohols, as well as sulfated salts hexa -, hepta - and octadecanol or fatty alcohol glycol ethers, condensation products of sulfonated naphthalene or its derivatives with formaldehyde, condensation products of naphthalene, respectively naphthalene sulfonic acid with phenol or formaldehyde, polyoxyethylene octylphenol ether, ethoxylated isooctyl-, octyl- or nonylphenol, alkylphenol - or tributylphenylpolyglycol ether, alkylaryl polyether alcohols, isotridecyl alcohol, ethylene oxide condensates of fatty alcohol, ethoxylated castor oil, polyoxyethylene alkyl ether or polyoxypropylene, polyglycol ether acetate of lauryl alcohols, complex ester with orbit, lignin sulfite spent alkali or methyl cellulose.

Powder, preparation for spraying and dusting can be obtained by mixing or co-grinding compounds I, II and IP or mixtures of compounds I, II and I with a solid filler.

Granules (eg coated, impregnated or homogenous) are usually obtained by combining the active substance or active substances with a solid filler.

As fillers, respectively, solid media serve, for example, mineral earths, such as silica gel, silicic acids, silicates, talc, kaolin, limestone, lime, chalk, bolus, loess, clay, dolomite, diatomaceous earth, calcium sulfate, sulfate magnesium, magnesium oxide, ground plastics, as well as fertilizers such as ammonium sulfates, ammonium phosphates, ammonium nitrates, ureas and vegetable products such as cereal flour, tree bark flour, wood flour and nut shell flour, cellulose powder or other solid fillers.

Ready preparations contain a total of 0.1 to 95 wt. 95, preferably from 0.5 to 90 wt. 90 compounds I or II, respectively, mixtures of compounds I and II. Active substances are used with purity from 9095 to 10095, preferably from 9595 to 10095 (according to the NMR spectrum or HCVT).

The application of compounds І, ІІ and І, or mixtures of the corresponding preparation forms is carried out in such a way that phytopathogenic fungi, their growth space (biotope) or plants that are subject to protection from them, seeds, pounds, surfaces, materials or premises are treated with a fungicidally effective amount of the mixture , respectively, compounds I, II and IP when applied separately.

Processing can be carried out before or after damage by phytopathogenic fungi.

Application example

The synergistic effectiveness of mixtures according to the invention can be shown in the following experiments:

The active substance is prepared separately or together as a 1095th emulsion of 63 wt. 96 of cyclohexanone and 27 wt. 90% emulsifier and dilute with water in accordance with the desired concentration.

The assessment is carried out by determining the affected sheet surfaces in percentage. These percentage values are converted into efficiency. Effectiveness (MU) is determined by the Abbott formula:

MU - (1-a/B):100, in which a corresponds to the defeat of treated plants by fungi in 95 and

B corresponds to fungal damage to untreated (control) Udo plants.

At an efficiency equal to 0, damage to treated plants corresponds to the efficiency of untreated plants; at an efficiency equal to 100, the treated plants have no damage.

The expected effectiveness of mixtures of the active substance is determined by the formula of Colby IN.5. SoIBu, M/evadv5 15, 20-22 (1967)| and compared with established efficiency. Colby's formula: E-x nu-x: y/100

E is the expected efficiency, expressed in 95% of untreated control plants, when using a mixture of active substances A and

B with concentrations a and b. X efficiency, expressed in 95% of untreated plants, when using the active substance A with a concentration of a. in efficiency, expressed in 90 from untreated plants, when using the active substance B with a concentration of 6.

Application example 1:

Protective action against powdery mildew of wheat, which is caused by Eguzirpe (sup. Vistetgia) dgatipiv gta z5resiaiiv (si

The leaves of wheat sprouts of the "Kaplgiei" variety grown in pots are sprayed with an aqueous solution of the active substance, which was prepared from a basic solution consisting of 10 95 active substance, 85 95 cyclohexanone and 5 95 emulsifier, until the formation of drops, and 24 hours after drying the sprayed layer is dusted spores of powdery mildew of wheat (Eguzirpe |zup. Viitepa| dgatipiv gpta z5resiaiiv. (si).

The studied plants are placed in a greenhouse at a temperature between 20 and 2470 and a relative humidity of air from 60 to 90 95. After 7 days, the degree of damage by powdery mildew of plants is visually determined at 95 of the total surface of the leaves.

Visually determined values of the percentage of damage to the surfaces of the leaves of the plants are listed in the efficiency as 905 of the untreated control. A potency of 0 corresponds to a lesion as in the untreated control, a potency of 100 corresponds to 0,956 lesions. The expected effectiveness of combinations of active substances is determined by the Colby formula (SoiIru, 5. V. (SaiIsshaipod 5upegdivis apa apiadopiviis gezropvez oi Ppegiside Sotbipayopv", M/eedv, 15, pp. 20 - 22, 1967) and compared with the observed effectiveness.

Table 1: Active substance Concentration of active substance and Uzi effectiveness: | substances in solution for and from ! and spraying in mi. at; nmeoprocessed and

YControl Hek, lesion) : o N : I N :

Tsnaoprachov.) and and:

POP PI PN i1bnoluka G2V I 0.25 and and I : 0425 ! in? ! : ! vv I 36 : ' and Z polu I tank Y 75 N ! ! ! and

I ! 0125 and 57 and : ! !

I and ov I 6!

POPI MINA NN gbpopuka Db H 2.5 to her? and and» pyraclostrovin! 125 47 : ; ov zv i i ; | ! BE VE VYT! | 125 25;

I I ve 25 and ddtntntrtnnntnfrnnn nd ibpopuka NO | 125 4 and iv vpoksukonva 06 4 ! ! ! | 03 4 and

Double Amounts ' Double Effectiveness, which Calculated on LANGUAGE 00001 will be pasted | efficiency"):

Se compound I-V E 10195 5 3.25 mil, part. va and 4:40! their smart A! !

Yepoluka 128 t pk dpoluka NO! 10.08 and 0 mip. often 75: pl Ff I them pumvn V !

Fplopuka in TT 1 popuka M-6: 0.195 20.8 mil. often 89! and 8) skh sums with and pOpoluka 128 and the same compound T.V 05 125 mil, chast. Yo!

TSI:c): in the bag 0 AND NN,

Set nezhynnnini now, sir, eat epoluka 12! ! 10125 2 1.95 ml. often 84! ear: sad Sh | and

Compound 1-28. | ! and 19 compound 1-12 | And! doviaovmiya chat | and 1:10) pe vumam | and "Eblopuka 1-88 our same E same sloluka P-12 | ! 1025 54.25 million. frequent: ! in Y i

In!

Double mixtures 1 Laundry combinations | Effectiveness of which 000 Calculated dent is checked for efficiency

Ibpopuua OB company 1 opoluka Ts-YAA | : and tin rush | 89 and

THESE: 6) | and !

Speluka ZU and drink compound N-b! and !

TOMY 125 miles. often in:

TSO | I and the mixture I and "bloluka 3? | t t

TE compound 1-8 N and: 10.08 w 0.8 vol. often, | and and and

This | I ! and: boomed 4 and and and

PEpoluka THIS? ! non popa ik opopuka Sh-a | eh! 10/35 k 1.25 my. frequent: | 89 and I 8) ! | : :1" knew K and I :

Faolyaa BOTTTT p: with compound IV | ! ov ob milchast 79 :

ЧЕ: В : : зас ХНИ пи MA : ibpoluka WITHOUT | and shE and the compound MT? and and 1025 and 5 million. often, | va and tsa) : ! their thoughts are mine

Fpoluyua and 0000 Y I ni III

FROM spopuk ON Ya iyoBovmipchaet and Z Ya

CHE: and : and sums of M and. and

Double suknml 100 Double combinations and Efficiency that | Calculated other quality efficiency:

IPopuka 37: tt izh connection ST? and 1025 is 125 mine. often | 85 and:

NO:5) and : : peoumiO SHO and !

Fbaavua 37 00 re PATO compound; : 10125 06 mi. often : vk | H :5) : | ! pa p JUICES tTable 7 child's dettlnnnia t UN SAD pornlnnnntnnnntontjnnntnnnh

G"Triple combinations of drugs | Effectiveness that is Calculated: by the invention | observed | effectiveness") from the compound ЦЯ | : eat the connection to it 1 | 50 E 1.125 125 51.25 ml. often, | IS

These:10: 10) | : umvnA with 125 miles, chast tk 1Spopuka 1-78 And : iv slopukv Also and !

Iv compound Still Yi vu | in : povo bsilence | and:

THIS:10:39) and ! ! isumnia B is 0.0 mil. often More | ши шш тот НИ ШИ МИ иже connection Ts-AB and : and" vpaluka Nil and 100 ve ! the lion's share is frequent; led, and after ana in ANNA PAN,

And notary hombinations of zidnei| Bojectivity, which | "Calculated and observed by the invention (effectiveness) of the present invention 13 compound 1-6. and 1. compound Na B which:

Ivlav 08 "03 miya. often eat

This: in: 25) and isumivv 5 0.5 vil. often This one:

Ishvonuya MO not 12 sloluka 1-8 N

M compound NEa 106 va : ii.25 1.95 z 1.25. My; myst. and:

THIS:5:8) | : a mixture of Z Z 1.25 ml. Art. M12! iv compound ia cho 85 :

I6.125 1.25 and 1.95 mil. often : y: isumish BE I ЗB me mat. N

NOT i i : puta IN OTIT

TE compound H-12: 12 opopuka yba 89 vo! rov'ya oz ov miv. pastor : (forehead) | : isumish kv OV mio chast. Pra and '

Yelopuka 128 vovi in ! their compound Ts-12 | :

Tk compound Na | 190 85 I 1025 25 15 circles. often | I

SHIV:5) And : umish Fo 195 ill. often and there is no KVN SUA autopsy

Petri dish combinations are identical! 8) efficiency of nka | Calculated by the invention of 0001, it is possible efficiency") !

I(bpopuyuyoV now p i 12 popukka 1-12 i | : 1» opuluha Sh.a | tb i 65 : 10255 1.25 x 0.8 mil, chast. | | ! tsiv: A i : isumny bek Ob mip. chast; | | In pa and:

ISvopuka Go : I y y y their connection Ts-y2 | ' I 1 compound Sha ! then I 53 and le ov pil chast. | ! I (55 | : ivumna N I 0.6 my, chast. i pa sh ! i

ФШладуя Я ОТ ши ши t из compound ЯВ | and : 19 compound Sha | 100! about:

Pa i 25 x 185 Mil. substitute, | And

To) | I: 15.25 million Yesums. often, | ! not Misha n VO

Compound 37 | and !

PE opoluka TV N and ; 13 compound Sha | 3 I 85: 10.6 08 06 million. often And:

This: moose | | : isumium 450.8 mya. often, | And!

On:

BedTTTTTTTTt is a temptation! ! 12 opopuka IN.a. 106 | that E 105 On I 125 miles often. | ;

Ts:5:5) Mixture Every 225 mi. chaf.| | !

you can see VYN SM 0 stronghold and Petri'nii comonations zdno a Effectiveness, which is divided:

Ro The invention is effective) ! pepoluya BYAH OT izhepopuka THIS IS I 1 stpopuka On that 80 ! ivebya av zhrbmilchmast. | and

This:in:2 | | ! amount of KO 0.5 circles. often, I.V | | and

Papoluka 157 pn nin izh compound P-b | and their temptation is not 79!

I0.1285 5 0.6 0.8 mip. often | and

Nepv:c) | ! is a mixture of 0.6 ml. often Sha 4 Ya

Shptluyu iy 0000 pi izh compound 1st | : ik compound No a And I And what '

Ib.tav kb om chast | '

Bi?) and and and

Isuvt yin plya mil. mast Sha | And and the will of 7 pi mon pi python tutu spetzhstezhetch. it was eaten by a temptress 12: And ! 1 ополука Ин.а ! 100! 55! 1O/1O5 1.95 z 195 ml. often and ! pt: a: and and :

Isumne WHAT 395 measures. chast: and vka and 1: tOpopuka M? ! I and tk are a combination of IN! ! ! eat compound IN.a ! ВВ and 74 I ivbov ov ovmiychayeto | : :

Central Bank: I and I

Continuation of tyablpici and red nutu nd YN SUM rekonsntient and Petri combinations according to 5 Efficiency, which | calculated

I occasionally observe 1 efficiency) /

Evaluation of GT:

Tk epoluka 12 and ivspoluka Ka | then in and 1025 15 91.05 My. often | :

Ts: BIV) ! ! mixture 0 ok 25 ml. frequent: ini ii. ! ibnbluyua a? and mon nin from epoluk H-12 and! And N

Gk compound Ia! 100 And vu: took care of michvst. | !

I:5:25) | ! ! a mixture of 0.5 ml; often On Shk: popopuka 37 Y, etc

From the Ts-12 tank | IS

Ge dpoluka Na mia. often and then: Wow! nen! : : (Sopupuka KZ? and | І and connection іни and : И ! ik connection Na ! ZI I BE !

MUB Oh" 0.3 mip. often and I and js5:2c) : ! other results are calculated according to Colby's formula

It follows from the results of experiments that the efficiency observed for ternary mixtures is higher than the efficiency calculated by Colby's formula for double mixtures (from synerg. 1678. XI 5).