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Priority claimed from US08/665,775external-prioritypatent/US5804602A/en
Application filed by Gilford Pharmaceuticals IncfiledCriticalGilford Pharmaceuticals Inc
Priority claimed from PCT/US1997/010149external-prioritypatent/WO1997048409A1/en
Publication of UA72870C2publicationCriticalpatent/UA72870C2/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
The present disclosure relates to dipeptidase inhibitors, and more particularly, to novel methods of using phosphonate derivatives, hydroxyphosphinyl derivatives, and phosphoramidate derivatives to inhibit N-Acetylated ?-Linked Acidic Dipeptidase (NAALADase) enzyme activity, and to treat prostate diseases, especially using the compounds of the present invention for the inhibition of the growth of prostate cancer cells.
UA98126689A1996-06-171997-06-13Method for inhibiting growth of cancer cells using naaladase inhibitors
UA72870C2
(en)