UA65589U - Ultrapure aqueous composition of germanium with amino acid - Google Patents

Abstract

Ultrapure aqueous composition of germanium with amino acid comprises at least one amino acid from group comprising lysine, methionine, valine, isoleucine, leucine, threonine, tryptophane, phenylalanine, arginine, histidin, cystine, cysteine, tyrosine, glycine, serine, proline, alanine, hydroxy-proline, aspartic acid, glutamic acid. Amino-acid germanium complex is prepared by interaction of germanium nanoparticles, germanium oxide nanoparticles or germanium hydroxide nanoparticles with amino acid.

Claims (1)

( (1) МПК (2011.01) КИ СО7Е 7/30 (2006.01) М вв2В 3/00 СО7с 229/76 (2006.01) ДЕРЖАВНА СЛУЖБА видається під ІНТЕЛЕКТУАЛЬНОЇ Н й : ВЛАСНОСТІ о П И С виснуальнсть УКРАЇНИ ДО ПАТЕНТУ патенту НА КОРИСНУ МОДЕЛЬ ишиГлРОІОТЛМЛИЬЛЬЛИТЬЛЬЛЬЛИЛДИТЬТЬТЬЬТИЬНЬ6ИЬТЬШИЬИЬТЬТЬТНИТЬТНШЬЬИТСИТИТИОИООТИТИТОИОИИТИИЬЬИИИОИИИИОВЛЛЄОЄИЄЄИБИТНТЦИЖИЄ6ЦООЦТНИИТЛ ОІаІНШШШООЛІТОООЛЇИОООЛООЛЛЛТОООХТОЛИОІЕВПОВШ?ИЙЦТЬНТНТИТИТЬТЬТЬЬЬЬШЬОХОИТЬИЬТИТОИИОСХИХДТИОВИТХИХННЙКЙИХИТИИИИНИТТЯ (54) НАДЧИСТА ВОДНА КОМПОЗИЦІЯ ГЕРМАНІЮ З АМІНОКИСЛОТОЮ 1 2 (21) и2г0о1106148 амінокислотний комплекс германію, отриманий (22) 17.05.2011 взаємодією наночастинок германію, наночастинок (24) 12.12.2011 оксиду германію або наночастинок гідроксиду гер- (46) 12.12.2011, Byul.Mo 23, 2011. mania with amino acid. (72) KOSINOV MYKOLA VASILYOVYCH, KAPLU- 2. Ultrapure aqueous composition of germanium with amino acid- NENKO VOLODYMYR GEORGIYOVYCH slot according to claim 1, which is distinguished by the fact that 73) KOSINOV MYKOLA VASYLOVYCH, Capping the mass of amino acid k of germanium NENKO VOLODYMYR GEORGIYOVYCH to the mass of residual nanoparticles amounts to (57) 1. Ultrapure aqueous composition of germanium with at least 10,000 amino acid, preferably at least one amino acid from the group that includes lysine, methionine, valine, 3. An ultrapure aqueous composition of germanium with the amino acids - isoleucine, leucine, threonine, tryptophan, phenylalasolate according to claim 1, which differs in that it contains nin, arginine, histidine, cystine, cysteine, tyrosine, glycine - as a solvent or injection water, or deionicin, serine, proline, alanine, oxyproline, asparaginized water, or ordinary drinking water, or drinking water with acid, glutamic acid that has been boiled, or distilled water, or bidis water - differs in that the content of chloride-, nitrate-, thiolated, or purified water, or mineral-carbonate- and sulfate-ion water does not exceed 0.1 wt. 95, well, or mixtures of the specified waters. preferably does not exceed 0.01 wt. 9о, and contains - 1о The useful model belongs to the field of nanoteleucine, phenylalanine, lysine, lysine, methionine, triochnology and chemistry, more precisely to the compositions of amino acids nin, tryptophan, valine, alanine, glycine, arginine, hist- with trace elements , which are widely used din, or their mixture (Application of Russia MO 2002119628. (o) in the perfumery, food industry, in medicine, in agriculture, in biology, in the area of IPC AbTI2 /16, Ab112/18, A23I3/34. Publ. IR F) those of industrial organic synthesis. 10.06.2004). IF) A well-known composition of trace elements with amino acids. The disadvantage of the composition is high toxicity, which (Se) lots containing trace elements in the form of minerals is due to the fact that together with the necessary micro-etral salts (USSR Patent M 1380618, cl. СО7С elements in it are contained in a large amount of chlorine-Ka 51/41, 1988). lead ions The disadvantage of the composition is toxicity and expensive. The ultra-pure composition of selenium from the resulting product is known, as the process is carried out with additives: amino acid arginine 30-600 mg, amino acids can be carried out in very dilute solutions of lota valine 15-300 mg, amino acid histisine 15-300 or in a heterogeneous environment, which reduces the output mg, amino acid isoleucine 10-200 mg, amino acid- - and complicates the process of isolation and purification of target and leucine 20-400 mg, amino acid lysine 15-300 mg, b products. In addition, the target product contains amino acid methionine 5-300 mg, amino acid tresh chloride, nitrate, carbonate or sulfate ions, which onine 10-200 mg, amino acid tryntophan 5-100 mg, increases the toxicity of the product. amino acid phenylalanine 5-300 mg, linoleic acid - a well-known metal chelate complex compound, lota 50-500 mg, arachidonic acid 50-500 mg containing at least one metal from the group that (Application of Russia Mo 2002127403. VITAMINS - includes selenium, copper, zinc, mercury, chromium, manganese, MINERAL COMPLEX, METHOD OF ITS PRODUCTION - nickel, cadmium, arsenic, cobalt, aluminum, lead, PREPARATION AND METHOD OF ITS ACCEPTANCE. IPC platinum, gold, titanium, tin, and as a chelate A2311/30, Ag2311/302, Ag2311/304, A2gZ31I 1/305. the ligand contains one of the following amino acids: iso- Publ. 27.12.2004). The disadvantage is the presence of impurities in the composition. The ratio of the mass of aminocarboxylate of metal to metals in the form of inorganic salts, which reduces its mass of residual nanoparticles to less than 10,000 and increases its toxicity. leads to an increase in toxicity due to current- The closest to the one claimed is the density of nanoparticles. organogermanium compound of a high degree of purity Ultrapure aqueous composition of germanium from amino acid containing carboxyethylgermaniumsesquioxide with acid contains as a solvent or water (Application of Russia Mo 96121565. METHOD OF OBTAINING injection, or deionized water, or drinking water GERMANIORGANIC COMPOUND, NOT ordinary, or boiled drinking water, or dis- CONTAINING GERMANIUM DIOXIDE AND METHYLATED water, or bidistilled water, or purified TALLIC GERMANIUM IN TOXIC water, or mineral water or mixtures of the specified QUANTITIES. IPC СО7Е7/30. Publ. water. This expands the field of application of the composition 27.12.2004). tions The disadvantage is the presence of sulfate in the composition. The composition contains at least one amino ion. an acid from the group that includes lysine, methionine, valine, Isoleucine, leucine, threonine, tryptophan, phenylala is the basis of a useful model - reducing toxicity and increasing environmental nin, arginine, histidine, cystine, cysteine, tyrosine, gly- composition of amino acids with germanium. tin, serine, proline, alanine, oxyproline, asparagino- Proposed, as well as known ultrapure aqueous acid, glutamic acid. This expands the composition of germanium with the amino acid it contains, which is the field of its application. at least one amino acid from the group that includes Lysine lowers the level of triglycerides in the serum of lysine, methionine, valine, isoleucine, leucine, threonine, blood. It is necessary for normal tryptophan, phenylalanine, arginine, histidine, cystine, bone formation and growth of children, promotes the assimilation of calcium and cysteine, tyrosine, glycine, serine, proline, alanine, and supports normal nitrogen metabolism in adults. oxyproline, aspartic acid, glutamic acid. Methionine helps the processing of fats, ash, and, according to this proposal, its content prevents their deposition in the liver and in the walls of arteries, chloride, nitrate, carbonate, and sulfate ions. promotes digestion, provides detoxification, exceeds 0.1 wt. 95, preferably does not exceed 0.01 processes, reduces muscle weakness, protects against masses. 905, and contains an amino acid complex of herma- action of radiation, useful for osteoporosis and chemical nia, obtained by the interaction of nanoparticles of herma-allergy, has a pronounced antioxidant effect, oskinium, nanoparticles of germanium oxide or nanoparticles are a good source of sulfur, which inactivates large germanium hydroxide plaster with amino acid. Free radicals. this ratio of the mass of the amino acid complex - Valine has a stimulating effect, necessary for sa germanium to the mass of residual nanoparticles of metabolism in the muscles, the restoration of damaged amounts to at least 10,000, preferably not tissues and to maintain normal nitrogen in the orga- less than 100,000, and as the composition of the solvent is low. contains either water for injection or deionized water, Isoleucine stabilizes and regulates the sugar level in either ordinary drinking water or drinking water of boiling blood and energy supply processes. Either distilled water or bidistilled water is necessary for the synthesis of hemoglobin. bathtub Leucine reduces the level of sugar in the blood and stimulates the content of chloride, nitrate, carbonate and the release of growth hormone. of sulfate ions does not exceed 0.1 wt. 95, preferably Phenylalanine is used in the treatment of blackberries - does not exceed 0.01 wt. 90. This allows you to reduce ringing, arthritis, depression, migraines. It affects the toxicity of the composition, improves environmental health, reduces pain, improves memory and the ability to think, and expands the scope of its application. When used to study, it suppresses the appetite. hundred chloride, nitrate, carbonate, and sulfate ions bi- Serine is necessary for normal metabolism of only 0.1 wt. 90 increases the toxicity of fats and fatty acids, the growth of muscle tissue and composition. maintenance of the normal state of the immune system. Ultrapure aqueous composition of germanium with amino Synthesized in the body from glycine. acid contains the amino acid complex germanium. Arginine is an important metabolic component in the body, obtained by the interaction of germanium nanoparticles with muscle tissue, helps to maintain an optimal body, germanium oxide nanoparticles, or nitrogen balance in the body, as it participates in the transport of germanium hydroxide nanoparticles with amino acids. and disposal of excessive azo- that one This makes it possible to increase its digestibility, sweat in the body. It helps to reduce weight, reduce the toxicity of the composition, increase environmental cleanliness and expand the scope of its application. body, has a stimulating effect on the production The ratio of the mass of the amino acid complex of insulin of the pancreas as a component of vasogermanium to the mass of residual nanoparticles of sclapressin (pituitary hormone) and helps the synthesis gives a value of at least 10,000, preferably not growth hormone. nshe 100,000. This makes it possible to obtain a clean and non-toxic composition that is ecologically Tryptophan is necessary for the production of the vitamin, because practically PP-niacin is used for the synthesis of all nanoparticles due to their high chemical value in the brain of serotonin, one of the most important activities involved in the formation of amino acids- neurotransmitters, used for insomnia, germanium complex. It also allows for depression and to stabilize the mood, to use to expand the scope of application of the composition in food for weight control, reduction of eyelashes in industry, in biology and medicine. appetite, as well as to increase the release of growth hormone. ammonia, subtracting nitrogen atoms in the process of formation Alanine contributes to the normalization of the metabolism of glu- another amino acid - glutamine. This process - eats goats. The relationship between the excess ammonia neutralization method in the brain, alanine and chronic fatigue syndrome has been established. ku. Glutamic acid is used to treat Proline improves the condition of the skin by alleviating muscular dystrophy, ulcers, hypoglycemic collagen production and reducing its loss, complications of insulin therapy, diabetes with age, helps in the restoration of cartilaginous vertebrae and disorders of mental development hon joints, strengthens ligaments and heart muscle. Glycine slows down the degeneration of muscle tissue - Tyrosine is involved in mood regulation; Denin, as it is a source of creatine - a substance, a deficiency of tyrosine leads to a deficiency of norepinephrine, which is contained in muscle tissue and is used by phrin, which, in turn, leads to depression. during the synthesis of DNA and RNA. Glycine is necessary for syn- Tyrosine suppresses appetite, helps reduce the breakdown of nucleic acids, bile acids and fat replacement, promotes the production of melatonin and other amino acids in the body. improves adrenal and thyroid gland functions Cystine strengthens connective tissues. and pituitary gland. Oxyproline makes up approximately 13 90 of the total Histidine contributes to the growth and restoration of tissue - the amino acid composition of collagen and gelatin. nin, is a part of myelin sheaths, which Example. An ultrapure aqueous composition is protected by nerve cells, as well as the necessary nium with an amino acid is obtained in this way. Spo- for the formation of red and white blood cells. Nanoparticles in the form of aqueous tidine are obtained from the histidine, histamine is synthesized, a very important comcoloid solution of germanium nanoparticles, a component of many immunological reactions. clade, by ablation of germanium granules in water (see Threonine contributes to the maintenance of normal protein metabolism in the body. Threonine is found in the erosion-explosive dispersion of metals. heart, central nervous system, skeletal IPC B22E 9/14. Publ. 05/25/2007. Bul. Mo 7.). musculature and prevents the deposition of fats in Germanium granules are placed in a blood vessel for the liver, stimulates the immune system, as it promotes pro-spuration and is evenly placed on the bottom of the suction of antibodies. dynes between the electrodes. Water is poured into the vessel. Cysteine is a sulfur-containing amino acid that plays an important role in the processes of formation of skin tissues when pulses pass through the chains of granules. of electric current, in which the energy of pulses is part of the protein of nails, skin and hair, increases the energy of selenium sublimation, in the points of con- contributes to the formation of collagen and improves the elastic tacts of the granules with each other, there are spark differences and the texture of the skin. Cysteine neutralizes some series in which explosive toxic substances occur and protects the body from damage-dispersion of granules. In the discharge channels of the tempering action of radiation, one of the most powerful antiocracures reaches 10 thousand degrees. Areas of the surface of sidants. granules in the zones of spark discharges melt and disintegrate into nanoparticles and steam. balance in the processes occurring in the central nervous system; prevents both excessive splashing in the water, cooling in it and creating excitement, and excessive braking. Takes a colloidal solution of nanoparticles. participation in the processes of synthesis of amino acids in the liver, in a colloidal solution of germanium nanoparticles, plays an important role in metabolic processes. It of germanium oxide nanoparticles and hydrogen nanoparticles is useful for athletes, as well as in case of violation of the formed germanium furoxide, they add aminocations of the liver. Stimulates immunity due to hypoacid. Since the number of reagents does not include production of immunoglobulins and antibodies. no other substances, but nanoparticles practically Glutamic acid is a neurotransmitter that fully participates in the reaction of the formation of chelate transmits impulses in the central nervous system, complexes, then a product of high eco- plays an important role in carbohydrate metabolism and contributes to the does not contain extraneous penetration of calcium through the blood-brain barrier, in particular, chloride, nitrate, carbonate, and barrier. It can be used by sulfate ion cells. of the brain as a source of energy, neutralizes "Computer naverstka A Krulevskyi 00000000 Signature (01010100 ТиражоаЗприм./000Сс State Service of Intellectual Property of Ukraine, st. Urytskogo, 45, m. Kyiv, MSP, 03680, Ukraine SE "Ukrainian Institute of Industrial Property", str. Glazunova, 1, m. Kyiv - 42, 01601