UA49003C2 - Method of draft of menthyl ether of isovaleric acid. - Google Patents
Method of draft of menthyl ether of isovaleric acid.Info
- Publication number
- UA49003C2 UA49003C2 UA98074011A UA98074011A UA49003C2 UA 49003 C2 UA49003 C2 UA 49003C2 UA 98074011 A UA98074011 A UA 98074011A UA 98074011 A UA98074011 A UA 98074011A UA 49003 C2 UA49003 C2 UA 49003C2
- Authority
- UA
- Ukraine
- Prior art keywords
- isovaleric acid
- menthyl ether
- draft
- menthol
- catalyst
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Abstract
The invention relates to organic chemistry and may be used in chemicopharmaceutical industry, especially, for production of medication "Validol" that represents 25-30 percent solution of menthol in menthyl ether of isovaleric acid. Easy and ecological method is elaborated, which provides for high quality of menthyl ether of isovaleric acid (amount of admixture not more than 1 percent). Method includes reaction of menthol with isovaleric acid in presence of a catalyst. As a catalyst n-toluene sulfonic acid is used, molar ratio of above mentioned components is equal to 1,0:1,08 ( 1,1:0,015 ( 0,03 accordingly, process is made at the temperature of 105-125 °C with simultaneous distillation of water in the form of azeotrope mixture with isovaleric acid.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
UA98074011A UA49003C2 (en) | 1998-07-22 | 1998-07-22 | Method of draft of menthyl ether of isovaleric acid. |
RU99101027/04A RU2153488C1 (en) | 1998-07-22 | 1999-01-18 | Method of preparing menthyl isovalerate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
UA98074011A UA49003C2 (en) | 1998-07-22 | 1998-07-22 | Method of draft of menthyl ether of isovaleric acid. |
Publications (1)
Publication Number | Publication Date |
---|---|
UA49003C2 true UA49003C2 (en) | 2002-09-16 |
Family
ID=21689287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA98074011A UA49003C2 (en) | 1998-07-22 | 1998-07-22 | Method of draft of menthyl ether of isovaleric acid. |
Country Status (2)
Country | Link |
---|---|
RU (1) | RU2153488C1 (en) |
UA (1) | UA49003C2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2626978C1 (en) * | 2016-03-10 | 2017-08-02 | Открытое акционерное общество "Ирбитский химико-фармацевтический завод" | Method of producing validol |
-
1998
- 1998-07-22 UA UA98074011A patent/UA49003C2/en unknown
-
1999
- 1999-01-18 RU RU99101027/04A patent/RU2153488C1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2153488C1 (en) | 2000-07-27 |
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