UA39163C2 - Phospholipid derivatives having antitumor and/OR antiprotozoal activity, method for the preparation thereof, pharmaceutical composition based thereoN and method for the preparation of pharmaceutical composition - Google Patents

Phospholipid derivatives having antitumor and/OR antiprotozoal activity, method for the preparation thereof, pharmaceutical composition based thereoN and method for the preparation of pharmaceutical composition

Info

Publication number
UA39163C2
UA39163C2 UA93002238A UA93002238A UA39163C2 UA 39163 C2 UA39163 C2 UA 39163C2 UA 93002238 A UA93002238 A UA 93002238A UA 93002238 A UA93002238 A UA 93002238A UA 39163 C2 UA39163 C2 UA 39163C2
Authority
UA
Ukraine
Prior art keywords
pharmaceutical composition
preparation
antitumor
phospholipid derivatives
antiprotozoal activity
Prior art date
Application number
UA93002238A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Герхард НЬОСНЕР
Герхард НЕСНЕР
Юрій СТЕКАР
Юрий СТЕКАР
Петер Хільгард
Петер Хильгард
Бернхард Кутшер
Юрген ЕНГЕЛЬ
Юрген Энгель
Original Assignee
Аста Медіка Акціенгезельшафт
Аста Медика Акциенгезельшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аста Медіка Акціенгезельшафт, Аста Медика Акциенгезельшафт filed Critical Аста Медіка Акціенгезельшафт
Publication of UA39163C2 publication Critical patent/UA39163C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/66—Arsenic compounds
    • C07F9/70—Organo-arsenic compounds
    • C07F9/72—Aliphatic compounds

Abstract

The base of this invention is a task to create a pharmaceutical composition of more extended spectrum of action. Phospholipid derivatives of the general formula (I): where R5 denotes linear or branched (C10-C24)alkyl residue, which can contain between one and three double and/or triple bonds.
UA93002238A 1992-10-01 1993-09-30 Phospholipid derivatives having antitumor and/OR antiprotozoal activity, method for the preparation thereof, pharmaceutical composition based thereoN and method for the preparation of pharmaceutical composition UA39163C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4233044A DE4233044A1 (en) 1992-10-01 1992-10-01 Phospholipid derivatives that contain higher elements of the 5th main group

Publications (1)

Publication Number Publication Date
UA39163C2 true UA39163C2 (en) 2001-06-15

Family

ID=6469408

Family Applications (1)

Application Number Title Priority Date Filing Date
UA93002238A UA39163C2 (en) 1992-10-01 1993-09-30 Phospholipid derivatives having antitumor and/OR antiprotozoal activity, method for the preparation thereof, pharmaceutical composition based thereoN and method for the preparation of pharmaceutical composition

Country Status (23)

Country Link
US (2) US5449798A (en)
EP (1) EP0594999B1 (en)
JP (1) JP3688304B2 (en)
KR (1) KR100331367B1 (en)
CN (1) CN1055697C (en)
AT (1) ATE174030T1 (en)
AU (1) AU661795B2 (en)
BR (1) BR9303990A (en)
CA (1) CA2107439C (en)
DE (2) DE4233044A1 (en)
DK (1) DK0594999T3 (en)
EG (1) EG20258A (en)
ES (1) ES2125935T3 (en)
FI (1) FI111261B (en)
GR (1) GR3029423T3 (en)
HU (1) HU220593B1 (en)
IL (1) IL107141A (en)
MX (1) MX9306076A (en)
NO (1) NO305911B1 (en)
PH (1) PH29951A (en)
RU (1) RU2126413C1 (en)
UA (1) UA39163C2 (en)
ZA (1) ZA937282B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP026997A0 (en) 1997-11-07 1997-12-04 Resmed Limited Administration of cpap treatment pressure in presence of apnea
WO2004062594A2 (en) * 2003-01-09 2004-07-29 Zeneus Pharma Limited Antineoplastic ether lipid compounds with modifications at the sn-3 carbon
CA2632449A1 (en) 2005-12-19 2007-06-28 Aeterna Zentaris Gmbh Alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177216A (en) * 1974-06-21 1979-12-04 The Dow Chemical Company Novel tributyl (2,5-dihydroxyphenyl)phosphonium hydroxide inner salts
US4177716A (en) * 1978-02-21 1979-12-11 Gerald J. Bowe Automatic energy saver and fire damper for exhaust systems
JPS5984824A (en) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd Antitumor agent
EP0916343A1 (en) * 1989-09-27 1999-05-19 ASTA Medica Aktiengesellschaft use of alkzl phosphoric acid compounds for the treatment of psoriatic diseases
DE3942933A1 (en) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh USE OF ALKYLPHOSPHOLIPIDES AS ANTIVIRAL MEDICINAL PRODUCTS AND NEW PHOSPHOLIPID DERIVATIVES
DE4111105A1 (en) * 1991-04-05 1992-10-08 Max Planck Gesellschaft NEW ERUCYL, BRASSIDYL AND NERVONYL DERIVATIVES

Also Published As

Publication number Publication date
CA2107439A1 (en) 1994-04-02
DE4233044A1 (en) 1994-04-07
CA2107439C (en) 2006-08-15
FI934297A (en) 1994-04-02
FI934297A0 (en) 1993-09-30
NO305911B1 (en) 1999-08-16
CN1055697C (en) 2000-08-23
BR9303990A (en) 1994-06-14
IL107141A0 (en) 1993-12-28
JPH06199876A (en) 1994-07-19
ZA937282B (en) 1994-04-25
AU661795B2 (en) 1995-08-03
US5637577A (en) 1997-06-10
RU2126413C1 (en) 1999-02-20
EP0594999A1 (en) 1994-05-04
HU220593B1 (en) 2002-03-28
PH29951A (en) 1996-09-16
EP0594999B1 (en) 1998-12-02
NO933505L (en) 1994-04-05
CN1088583A (en) 1994-06-29
JP3688304B2 (en) 2005-08-24
DK0594999T3 (en) 1999-08-16
HU9302772D0 (en) 1993-12-28
DE59309182D1 (en) 1999-01-14
KR100331367B1 (en) 2002-11-13
ATE174030T1 (en) 1998-12-15
ES2125935T3 (en) 1999-03-16
HUT65681A (en) 1994-07-28
MX9306076A (en) 1994-05-31
IL107141A (en) 1998-01-04
US5449798A (en) 1995-09-12
AU4874793A (en) 1994-04-14
EG20258A (en) 1998-05-31
GR3029423T3 (en) 1999-05-28
KR940009201A (en) 1994-05-20
NO933505D0 (en) 1993-09-30
FI111261B (en) 2003-06-30

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