UA31438A - METHOD OF OBTAINING THE MEDICINAL PRODUCT "FAMOTIDINE" IN THE FORM OF TABLETS - Google Patents
METHOD OF OBTAINING THE MEDICINAL PRODUCT "FAMOTIDINE" IN THE FORM OF TABLETSInfo
- Publication number
- UA31438A UA31438A UA98094674A UA98094674A UA31438A UA 31438 A UA31438 A UA 31438A UA 98094674 A UA98094674 A UA 98094674A UA 98094674 A UA98094674 A UA 98094674A UA 31438 A UA31438 A UA 31438A
- Authority
- UA
- Ukraine
- Prior art keywords
- mixture
- tablets
- famotidin
- active substance
- castor sugar
- Prior art date
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
The invention relates to the chemical-and-pharmacological industry, in particular to the methods for manufacturing the drug formulations representing famotidin-containing tablets. The method claimed comprises mixing the active substance with the starch and the lactose, the wetting of the mixture and its granulation followed by the drying of the wet granules, dry pelleting, coating of the pellets and tableting. The active substance is represented by famotidin. The mixture is performed with the castor sugar and/or aerosil. The mixture is wetted in 5-15 % polyvinyl pyrrolidone or 5-15 % prolivinyl pyrrolidone solution with the addition of the castor sugar. The granuls are dried at 35-50 °С and then are coated with the mixture of calcium stearate and stearinic acid at a 1:1 ratio. Then the protective coating is layered on the tablets. The technical result being attained consists in stabilization of such a drug formulation during its manufacture, storage and use in the conformity with the main requirements of the pharmacopea providing for the attainment of the necessary standards pertaining to the pharmacotherapeutical properties of the substance.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
UA98094674A UA31438C2 (en) | 1998-09-02 | 1998-09-02 | METHOD OF OBTAINING FAMOTIDINE MEDICINAL PRODUCT IN THE FORM OF TABLETS |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
UA98094674A UA31438C2 (en) | 1998-09-02 | 1998-09-02 | METHOD OF OBTAINING FAMOTIDINE MEDICINAL PRODUCT IN THE FORM OF TABLETS |
Publications (2)
Publication Number | Publication Date |
---|---|
UA31438A true UA31438A (en) | 2000-12-15 |
UA31438C2 UA31438C2 (en) | 2002-04-15 |
Family
ID=63709778
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA98094674A UA31438C2 (en) | 1998-09-02 | 1998-09-02 | METHOD OF OBTAINING FAMOTIDINE MEDICINAL PRODUCT IN THE FORM OF TABLETS |
Country Status (1)
Country | Link |
---|---|
UA (1) | UA31438C2 (en) |
-
1998
- 1998-09-02 UA UA98094674A patent/UA31438C2/en unknown
Also Published As
Publication number | Publication date |
---|---|
UA31438C2 (en) | 2002-04-15 |
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