UA31438A - METHOD OF OBTAINING THE MEDICINAL PRODUCT "FAMOTIDINE" IN THE FORM OF TABLETS - Google Patents

METHOD OF OBTAINING THE MEDICINAL PRODUCT "FAMOTIDINE" IN THE FORM OF TABLETS

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Publication number
UA31438A
UA31438A UA98094674A UA98094674A UA31438A UA 31438 A UA31438 A UA 31438A UA 98094674 A UA98094674 A UA 98094674A UA 98094674 A UA98094674 A UA 98094674A UA 31438 A UA31438 A UA 31438A
Authority
UA
Ukraine
Prior art keywords
mixture
tablets
famotidin
active substance
castor sugar
Prior art date
Application number
UA98094674A
Other languages
Russian (ru)
Ukrainian (uk)
Other versions
UA31438C2 (en
Inventor
Марк Вольфович Штейнгарт
Микола Іванович Гончаров
Николай Иванович Гончаров
Нонна Миколаївна Скакун
Нонна Николаевна Скакун
Вадим Олександрович Заболотний
Вадим Александрович Заболотный
Віктор Петрович Георгієвський
Виктор Петрович Георгиевский
Людмила Борисівна Нельзева
Людмила Борисовна Нельзева
Людмила Сергіївна Бочарова
Галина Володимирівна Оболенцева
Галина Владимировна Оболенцева
Людмила Петрівна Брюзгінова
Людмила Петровна Брюзгинова
Ольга Всеволодівна Супрун
Ольга Всеволодовна Супрун
Ольга Володимирівна Серебрякова
Ольга Владимировна Серебрякова
Юрій Іванович Шульга
Юрий Иванович Шульга
Світлана Григорівна Шульга
Original Assignee
Спільне Українсько-Естонське Підприємство "Юкрест Інтерком Лтд" У Формі Товариства З Обмеженою Відповідальністю
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Спільне Українсько-Естонське Підприємство "Юкрест Інтерком Лтд" У Формі Товариства З Обмеженою Відповідальністю filed Critical Спільне Українсько-Естонське Підприємство "Юкрест Інтерком Лтд" У Формі Товариства З Обмеженою Відповідальністю
Priority to UA98094674A priority Critical patent/UA31438C2/en
Publication of UA31438A publication Critical patent/UA31438A/en
Publication of UA31438C2 publication Critical patent/UA31438C2/en

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  • Medicinal Preparation (AREA)

Abstract

The invention relates to the chemical-and-pharmacological industry, in particular to the methods for manufacturing the drug formulations representing famotidin-containing tablets. The method claimed comprises mixing the active substance with the starch and the lactose, the wetting of the mixture and its granulation followed by the drying of the wet granules, dry pelleting, coating of the pellets and tableting. The active substance is represented by famotidin. The mixture is performed with the castor sugar and/or aerosil. The mixture is wetted in 5-15 % polyvinyl pyrrolidone or 5-15 % prolivinyl pyrrolidone solution with the addition of the castor sugar. The granuls are dried at 35-50 °С and then are coated with the mixture of calcium stearate and stearinic acid at a 1:1 ratio. Then the protective coating is layered on the tablets. The technical result being attained consists in stabilization of such a drug formulation during its manufacture, storage and use in the conformity with the main requirements of the pharmacopea providing for the attainment of the necessary standards pertaining to the pharmacotherapeutical properties of the substance.
UA98094674A 1998-09-02 1998-09-02 METHOD OF OBTAINING FAMOTIDINE MEDICINAL PRODUCT IN THE FORM OF TABLETS UA31438C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UA98094674A UA31438C2 (en) 1998-09-02 1998-09-02 METHOD OF OBTAINING FAMOTIDINE MEDICINAL PRODUCT IN THE FORM OF TABLETS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UA98094674A UA31438C2 (en) 1998-09-02 1998-09-02 METHOD OF OBTAINING FAMOTIDINE MEDICINAL PRODUCT IN THE FORM OF TABLETS

Publications (2)

Publication Number Publication Date
UA31438A true UA31438A (en) 2000-12-15
UA31438C2 UA31438C2 (en) 2002-04-15

Family

ID=63709778

Family Applications (1)

Application Number Title Priority Date Filing Date
UA98094674A UA31438C2 (en) 1998-09-02 1998-09-02 METHOD OF OBTAINING FAMOTIDINE MEDICINAL PRODUCT IN THE FORM OF TABLETS

Country Status (1)

Country Link
UA (1) UA31438C2 (en)

Also Published As

Publication number Publication date
UA31438C2 (en) 2002-04-15

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