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Application filed by Іван Олексійович Лісняк, Иван Алексеевич Лисняк, Анатолій Сергійович Тимченко, Анатолий Сергеевич Тимченко, Альберт Васильович Сиромятников, Альберт Василиевич СыромятниковfiledCriticalІван Олексійович Лісняк
Priority to UA98041740ApriorityCriticalpatent/UA30651A/en
Publication of UA30651ApublicationCriticalpatent/UA30651A/en
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Peptides Or Proteins
(AREA)
Abstract
The method for obtaining of plasma protein components is offered. In a method after the chromatographic purification with anti-virus treatment by detergent and further their elimination an albumen, immunoglobulin “G”, VIII and IX factors of the coagulation are obtained. The plasma is treated by anti-virus treatment. The chromatographic purification is carried out by ion-exchange chromatography, affine chromatography, gel-chromatography, and by adjustment of chromatographic eluents and caariers. Thus the waste fractions of plasma protein are used and additionally the Ig and IgM immunoglobulins, the factor VIIIR, antithrombin-III, ffibronectin, fibrinogen and alfa-I-antitrypsin factor are obtained. Detergents used for anti-virus treatment go out on every stage of chromatography in a free volume.
UA98041740A1998-04-071998-04-07Method for obtaining of plasma protein components
UA30651A
(en)
One-step procedure for the rapid isolation of mouse monoclonal antibodies and their antigen binding fragments by fast protein liquid chromatography on a mono Q anion-exchange column