UA112407C2 - AGOMELATIN CO-CRYSTALS, THE METHOD OF THEIR MANUFACTURING, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

AGOMELATIN CO-CRYSTALS, THE METHOD OF THEIR MANUFACTURING, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

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Publication number
UA112407C2
UA112407C2 UAA201206840A UAA201206840A UA112407C2 UA 112407 C2 UA112407 C2 UA 112407C2 UA A201206840 A UAA201206840 A UA A201206840A UA A201206840 A UAA201206840 A UA A201206840A UA 112407 C2 UA112407 C2 UA 112407C2
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Ukraine
Prior art keywords
crystals
agomelatin
manufacturing
pharmaceutical compositions
compositions containing
Prior art date
Application number
UAA201206840A
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Ukrainian (uk)
Inventor
Летеллієр Філіпп
Лінч Майкл
Пеан Жан-Мануель
Original Assignee
Ле Лаборатуар Сервьє
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Application filed by Ле Лаборатуар Сервьє filed Critical Ле Лаборатуар Сервьє
Publication of UA112407C2 publication Critical patent/UA112407C2/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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    • A—HUMAN NECESSITIES
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    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P3/00—Drugs for disorders of the metabolism
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    • A61P3/00—Drugs for disorders of the metabolism
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Новий співкристал агомелатину, що складається з:агомелатину, або N-[2-(7-метокси-1-нафтил)етил]ацетаміду формули (І):, (I)таорганічної кислоти.Винахід стосуться також лікарських засобів, що містять співкристали агомелатину з органічними кислотами.A new agomelatine co-crystal consisting of: agomelatine or N- [2- (7-methoxy-1-naphthyl) ethyl] acetamide of formula (I) :, (I) inorganic acid. The invention also relates to medicines containing agomelatine co-crystals with organic acids.

UAA201206840A 2011-06-09 2012-06-05 AGOMELATIN CO-CRYSTALS, THE METHOD OF THEIR MANUFACTURING, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM UA112407C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1101766A FR2976284B1 (en) 2011-06-09 2011-06-09 NOVEL CO-CRYSTALS OF AGOMELATIN, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (1)

Publication Number Publication Date
UA112407C2 true UA112407C2 (en) 2016-09-12

Family

ID=46690337

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201206840A UA112407C2 (en) 2011-06-09 2012-06-05 AGOMELATIN CO-CRYSTALS, THE METHOD OF THEIR MANUFACTURING, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (6)

Country Link
CN (1) CN102816079B (en)
AP (1) AP3198A (en)
CU (1) CU20120086A7 (en)
FR (1) FR2976284B1 (en)
HK (1) HK1178881A1 (en)
UA (1) UA112407C2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2810647A1 (en) * 2013-06-06 2014-12-10 Zentiva, a.s. Pharmaceutical formulations comprising agomelatine in the form of agomelatine co-crystal with an organic acid
ES2645223T3 (en) * 2013-06-06 2017-12-04 Zentiva, K.S. Agomelatine formulations comprising agomelatine in the form of co-crystals
ES2959460T3 (en) * 2015-03-31 2024-02-26 Fis Fabbrica Italiana Sintetici Spa solid form of agomelatine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE457089B (en) * 1986-02-05 1988-11-28 Sandvik Ab PROVIDED TO TREAT A MIXTURE OF CARBON METAL BODIES TO Separate THESE FROM EACH OTHER ON THE BASIS OF THEIR COMPOSITIONS AND / OR STRUCTURES
FR2866335B1 (en) * 2004-02-13 2006-05-26 Servier Lab NEW PROCESS FOR THE SYNTHESIS OF AGOMELATIN
EA200970806A1 (en) * 2007-02-27 2010-08-30 Вертекс Фармасьютикалз Инкорпорейтед SOCRYSTALS AND CONTAINING THEIR PHARMACEUTICAL COMPOSITIONS

Also Published As

Publication number Publication date
FR2976284B1 (en) 2013-05-24
AP2012006308A0 (en) 2012-06-30
CN102816079A (en) 2012-12-12
CU20120086A7 (en) 2014-01-29
HK1178881A1 (en) 2013-09-19
FR2976284A1 (en) 2012-12-14
CN102816079B (en) 2015-04-08
AP3198A (en) 2015-03-31

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