UA111731C2 - STABILIZED COMPOSITION CONTAINING ANTIBODY TO INTERLAYKIN-4 (IL-4R) RECEPTOR, OPTIONS - Google Patents

STABILIZED COMPOSITION CONTAINING ANTIBODY TO INTERLAYKIN-4 (IL-4R) RECEPTOR, OPTIONS

Info

Publication number
UA111731C2
UA111731C2 UAA201305598A UAA201305598A UA111731C2 UA 111731 C2 UA111731 C2 UA 111731C2 UA A201305598 A UAA201305598 A UA A201305598A UA A201305598 A UAA201305598 A UA A201305598A UA 111731 C2 UA111731 C2 UA 111731C2
Authority
UA
Ukraine
Prior art keywords
receptor
composition containing
interlaykin
options
containing antibody
Prior art date
Application number
UAA201305598A
Other languages
Ukrainian (uk)
Inventor
Деніел Б. Дікс
Сяолінь Тан
Original Assignee
Рідженерон Фармасьютікалз, Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рідженерон Фармасьютікалз, Інк. filed Critical Рідженерон Фармасьютікалз, Інк.
Priority claimed from PCT/US2011/054856 external-priority patent/WO2012047954A1/en
Publication of UA111731C2 publication Critical patent/UA111731C2/en

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Винахід стосується стабільної рідкої фармацевтичної композиції, що містить людське антитіло, яке специфічно зв'язується з рецептором людського інтерлейкіну-4 (hIL-4R), де антитіло містить варіабельну ділянку важкого ланцюга, що містить амінокислотну послідовність SEQ ID NO: 1, і варіабельну ділянку легкого ланцюга, що містить амінокислотну послідовність SEQ ID NO:5, а також ацетат, гістидин, сахарозу, полісорбат, аргінін.The invention relates to a stable liquid pharmaceutical composition containing a human antibody that specifically binds to the human interleukin-4 receptor (hIL-4R), where the antibody contains a heavy chain variable region containing the amino acid sequence of SEQ ID NO: 1, and the variable sequence light chain containing the amino acid sequence of SEQ ID NO: 5, as well as acetate, histidine, sucrose, polysorbate, arginine.

UAA201305598A 2010-10-06 2011-05-10 STABILIZED COMPOSITION CONTAINING ANTIBODY TO INTERLAYKIN-4 (IL-4R) RECEPTOR, OPTIONS UA111731C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39028310P 2010-10-06 2010-10-06
PCT/US2011/054856 WO2012047954A1 (en) 2010-10-06 2011-10-05 Stabilized formulations containing anti-interleukin-4 receptor (il-4r) antibodies

Publications (1)

Publication Number Publication Date
UA111731C2 true UA111731C2 (en) 2016-06-10

Family

ID=45995014

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201305598A UA111731C2 (en) 2010-10-06 2011-05-10 STABILIZED COMPOSITION CONTAINING ANTIBODY TO INTERLAYKIN-4 (IL-4R) RECEPTOR, OPTIONS

Country Status (13)

Country Link
AR (1) AR083338A1 (en)
DK (2) DK2624865T3 (en)
ES (2) ES2820246T3 (en)
HK (1) HK1258305A1 (en)
HR (1) HRP20181822T1 (en)
HU (1) HUE052089T2 (en)
LT (1) LT2624865T (en)
PT (1) PT3354280T (en)
RS (1) RS57850B1 (en)
SI (1) SI2624865T1 (en)
TW (6) TWI718890B (en)
UA (1) UA111731C2 (en)
UY (1) UY33652A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201500889TA (en) 2012-08-21 2015-03-30 Sanofi Sa Methods for treating or preventing asthma by administering an il-4r antagonist
TWI709411B (en) * 2013-06-21 2020-11-11 法商賽諾菲生物技術公司 Use of an il-4r antagonist for the manufacture of a medicament for treating nasal polyposis
HUE046410T2 (en) * 2013-06-21 2020-03-30 Sanofi Biotechnology Methods for treating nasal polyposis by administering an il-4r antagonist
EP3218412A1 (en) 2014-11-14 2017-09-20 Sanofi Biotechnology Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist
PL3703818T3 (en) 2017-10-30 2024-03-25 Sanofi Biotechnology Il-4r antagonist for use in a method for treating or preventing asthma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7608693B2 (en) * 2006-10-02 2009-10-27 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human IL-4 receptor
ES2332082B1 (en) * 2008-07-24 2010-10-26 Consejo Superior De Investigaciones Cientificas (Csic) 45% PATTERN ALIGNMENT SYSTEM IN A SUBSTRATE BY LITOGRAPHY BY ESTENCIL.
WO2010029664A1 (en) * 2008-09-10 2010-03-18 日本エクスラン工業株式会社 Crosslinked acrylate-based fibers and the production thereof
BRPI1006519A2 (en) * 2009-03-06 2016-08-09 Genentech Inc antibody formulation

Also Published As

Publication number Publication date
TW201716086A (en) 2017-05-16
TWI679988B (en) 2019-12-21
TWI782325B (en) 2022-11-01
TWI690329B (en) 2020-04-11
DK3354280T3 (en) 2020-09-28
DK2624865T3 (en) 2018-10-22
UY33652A (en) 2012-04-30
TW202320851A (en) 2023-06-01
ES2820246T3 (en) 2021-04-20
LT2624865T (en) 2018-10-25
SI2624865T1 (en) 2018-10-30
TW202026011A (en) 2020-07-16
PT3354280T (en) 2020-09-01
HRP20181822T1 (en) 2018-12-28
TW202102262A (en) 2021-01-16
RS57850B1 (en) 2018-12-31
ES2687813T3 (en) 2018-10-29
HK1258305A1 (en) 2019-11-08
TW201542229A (en) 2015-11-16
TW201924718A (en) 2019-07-01
AR083338A1 (en) 2013-02-21
TWI568445B (en) 2017-02-01
TWI498121B (en) 2015-09-01
TW201221141A (en) 2012-06-01
HUE052089T2 (en) 2021-04-28
TWI718890B (en) 2021-02-11

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