UA108911C2 - ANTI-CANCER Fusion PROTEIN - Google Patents
ANTI-CANCER Fusion PROTEINInfo
- Publication number
- UA108911C2 UA108911C2 UAA201308180A UAA201308180A UA108911C2 UA 108911 C2 UA108911 C2 UA 108911C2 UA A201308180 A UAA201308180 A UA A201308180A UA A201308180 A UAA201308180 A UA A201308180A UA 108911 C2 UA108911 C2 UA 108911C2
- Authority
- UA
- Ukraine
- Prior art keywords
- fusion protein
- sequence
- domain
- cancer fusion
- end point
- Prior art date
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Винахід стосується злитого протеїну, що містить: домен (а), який є функціональним фрагментом послідовності протеїну hTRAIL, причому даний фрагмент починається амінокислотою в позиції не нижче ніж hTRAIL95, або гомологом згаданого функціонального фрагмента, що має принаймні 70 % ідентичності до послідовності, і домен (b), який є послідовністю імуностимулюючого ефекторного пептиду, при цьому послідовність домену (b) приєднана в точці С-кінця або точці N-кінця домену (а). Даний злитий протеїн може бути застосованим для лікування онкологічних захворювань.The invention relates to a fusion protein containing: domain (a), which is a functional fragment of the hTRAIL protein sequence, and the fragment begins with an amino acid at the position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% of the sequence and (b), which is the sequence of the immunostimulatory effector peptide, wherein the sequence of domain (b) is attached at the C-end point or the N-end point of the domain (a). This fusion protein can be used to treat cancer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL393146A PL393146A1 (en) | 2010-12-03 | 2010-12-03 | Anticancer fusion protein |
| PCT/EP2011/071719 WO2012072815A1 (en) | 2010-12-03 | 2011-12-05 | Anticancer fusion protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA108911C2 true UA108911C2 (en) | 2015-06-25 |
Family
ID=46210686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201308180A UA108911C2 (en) | 2010-12-03 | 2011-05-12 | ANTI-CANCER Fusion PROTEIN |
Country Status (2)
| Country | Link |
|---|---|
| PL (1) | PL393146A1 (en) |
| UA (1) | UA108911C2 (en) |
-
2010
- 2010-12-03 PL PL393146A patent/PL393146A1/en not_active Application Discontinuation
-
2011
- 2011-05-12 UA UAA201308180A patent/UA108911C2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL393146A1 (en) | 2012-06-04 |
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