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Application filed by Берингер Ингельхайм Интернациональ ГмбхfiledCriticalБерингер Ингельхайм Интернациональ Гмбх
Priority claimed from PCT/EP2010/054050external-prioritypatent/WO2010112437A1/en
Publication of UA106368C2publicationCriticalpatent/UA106368C2/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Abstract
The invention relates to novel 1,6-disubstituted pyrazolopyrimidinones of formula (I), in which is a tetrahydropyranyl-group and Ris the group V-W-*, whereby V and W independently of each other may be an aryl group or an heteroaryl group, which independently of each other may optionally be substituted. According to one aspect of the invention the new compounds are for use as medicaments or for the manufacture of medicaments, in particular medicaments for the treatment of conditions concerning deficits in perception, concentration, learning or memory. The new compounds are also for the manufacture of medicaments and/or for use in the treatment of e.g. Alzheimer's disease, in particular for cognitive impairment associated with Alzheimer's disease.
UAA201112305A2009-03-312010-03-261-heterocyclyl-1,5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
UA106368C2
(en)
Salt(s) of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7h-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide and processes of making thereof
Novel 3,5-disubstituted-3h-imidazo[4,5-b]pyridine and 3,5- disubstituted -3h-[1,2,3]triazolo[4,5-b] pyridine compounds as modulators of c-met protein kinases