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Application filed by Эвек Инк., Берингер Ингельхайм Интернациональ ГмбхfiledCriticalЭвек Инк.
Priority claimed from PCT/US2008/012680external-prioritypatent/WO2009064399A1/en
Publication of UA102085C2publicationCriticalpatent/UA102085C2/en
Disclosed herein are anti-hGM-CSF monoclonal antibodies and antigen-binding fragments of such antibodies, with improved neutralizing capacity to hGM-CSF activity. Pharmaceutical compositions comprising such an antibody or antigen-binding fragment are also provided. The present invention is useful for the treatment of various diseases that are associated with aberrant expression of hGM-CSF.
UAA201009126A2007-11-132008-11-12ISOLATED MONOCLONAL ANTIBODY THAT BINDS TO hGM-CSF AND COMPOSITION COMPRISING SAME
UA102085C2
(en)
Monoclonal antibody or antigen-binding fragment thereof, pharmaceutical compositions comprising the same and use thereof for the manufacture of medicaments for the treatment of cancer