TWM641051U - An electrophoresis device with defogging function - Google Patents

Abstract

An electrophoresis device with defogging function includes a light source module, an electrophoresis tank, a gel tray, a light-transmitting cover and a power supply module. The light source module includes a base and a light emitting element fixed on the base, and the light emitting element emits a light source upward. The electrophoresis tank is stacked on the light source module and includes a surrounding side wall, a light-transmitting bottom wall receiving the light source, and a pair of electrode groups. The light-transmitting bottom wall and the side wall jointly define a space, and the electrode group An electric field is provided in the space. The gel tray is arranged on the transparent bottom wall and located in the space. The light-transmitting cover is openably and closably arranged on the electrophoresis tank and includes a filter and an electric heating element embedded in the filter. The power supply module is electrically connected to the light source module, the electrophoresis tank and the electric heating element.

Description

An electrophoresis device with defogging function

The present invention relates to an electrophoresis device, in particular to an electrophoresis device with a defogging function.

Electrophoresis refers to the phenomenon that charged particles move towards the opposite electrode in a fluid under the action of an electric field. Electrophoresis is one of the commonly used methods for separating substances by virtue of the different moving rates of each substance.

Among them, the horizontal electrophoresis tank is used for nucleic acid electrophoresis of deoxyribose nucleic acid (DNA) and ribonucleic acid (RNA). Nucleic acids of different molecular weights move at different speeds in the colloidal pore, thereby separating nucleic acids of different sizes, and are stained and illuminated to facilitate users to observe the separation results.

A common horizontal electrophoresis tank usually includes a tank and a transparent cover. The tank can accommodate experimental gel plates and buffers for nucleic acid gel electrophoresis. Generally, the buffer located in the tank needs to be The liquid is heated, so the temperature will rise and mist will be generated on the cover, so that the user cannot directly observe the changes inside the tank through the cover, and if the mist is removed directly by hand, it is easy to cause electric shock and cause danger. In order to solve this problem , For example, Taiwan New Patent No. TW M616884 U discloses an "improved structure for defogging electrophoresis tanks". However, this defogging technology requires a manual operation mechanism to scrape off the fog. The design is more complicated and easy to damage, and it is easy to Incomplete scraping causes the problem that the line of sight is blocked. Therefore, the applicant believes that it is necessary to improve the defogging method of the existing electrophoresis tank.

The main purpose of the present invention is to improve the conventional electrophoresis equipment which needs to manually scrape off the mist during the electrophoresis process, which causes inconvenience.

To achieve the above purpose, the present invention provides an electrophoresis device with defogging function, including: a light source module, an electrophoresis tank, a gel tray, a light-transmitting cover and a power supply module. The light source module includes a base and a light emitting element fixed on the base, and the light emitting element emits a light source upward. The electrophoresis tank is stacked on the light source module and includes a surrounding side wall, a light-transmitting bottom wall receiving the light source, and a pair of electrode groups. The light-transmitting bottom wall and the side wall jointly define a space, and the electrode group An electric field is provided in the space. The gel tray is arranged on the transparent bottom wall and located in the space. The light-transmitting cover can be opened and closed on the electrophoresis tank and includes a filter and an electric heating element embedded in the filter. The power supply module is arranged on one side of the light source module, and is electrically connected to the light source module, the electrophoresis tank and the electric heating element.

The terminology used herein is only for the purpose of describing specific embodiments and not limiting the present invention. As used herein, the singular forms "a" and "the" may also include plural forms unless the context dictates otherwise.

The directional terms used herein, such as up, down, left, right, front, back and their derivatives or synonyms, refer to the orientation of elements in the drawings and do not limit the present invention, unless the context clearly states otherwise. Relevant detailed description and technical content of the present invention are described as follows with respect to matching drawings now.

Referring to "Fig. 1" and "Fig. 2", it is a three-dimensional assembly view and an exploded view of an embodiment of the present invention. The present invention discloses an electrophoresis device 1 with defogging function, including a light source module 10, an electrophoresis tank 20, a gel tray 30, a light-transmitting cover 40, and a power supply module 50, and the electrophoresis tank 20 is stacked On the light source module 10, the gel tray 30 is arranged in the electrophoresis tank 20 and the light-transmitting cover 40 is arranged on the electrophoresis tank 20 in an openable and closable manner. The gel tray 30 is used to carry a colloidal medium , and the sample to be analyzed is placed in the colloidal medium. The power supply module 50 is disposed on one side of the light source module 10 and is electrically connected to the light source module 10 , the electrophoresis tank 20 and the transparent cover 40 .

The light source module 10 includes a base 11 and a light emitting element 12 , the light emitting element 12 is fixed on the base 11 and emits a light source upward, and the base 11 includes two fixing protrusions 111 extending upward. In one example, the light emitting element 12 is an LED light bulb to save power consumption, and the light emitting element 12 can emit a blue light source with a wavelength of 470nm±10nm to excite fluorescent agents bound to nucleic acid or protein.

The electrophoresis tank 20 includes a side wall 21, a light-transmitting bottom wall 22 and a pair of electrode groups 23, the side wall 21 is arranged around, and the side wall 21 includes two fixing grooves 211 and two bosses 212, the fixing grooves 211 are set respectively corresponding to the fixing bumps 111, so that the electrophoresis tank 20 can be stacked on the light source module 10 stably, the boss 212 is formed to protrude upward from a top surface 21a of the side wall 21, and the transparent The light cover 40 is fixed on the boss 212 without directly contacting the top surface 21 a of the side wall 21 , which prevents electric power from being transmitted to the light-transmitting cover 40 during the electrophoresis process and causing electric shock.

The light-transmitting bottom wall 22 receives the light source emitted by the light-emitting element 12, and the light-transmitting bottom wall 22 and the side wall 21 jointly define a space 24, and the electrode group 23 provides an electric field in the space 24, and the gel The disc 30 is disposed on the transparent bottom wall 22 and located in the space 24 . Accordingly, the electric field generated by the electrode group 23 will act on the sample to be analyzed in the colloidal medium for colloid electrophoresis, and the light source is irradiated to the gel plate 30 through the transparent bottom wall 22. Accordingly, using The user can observe the gel plate 30 in real time. In one example, the light-transmitting bottom wall 22 is made of strengthened glass and bonded to the side wall 21 with double-layer waterproof glue to avoid cracking and liquid leakage.

In one embodiment, the electrophoresis tank 20 is a horizontal electrophoresis tank for colloid electrophoresis of protein, deoxyribonucleic acid (DNA) or ribonucleic acid (RNA), staining the nucleic acid or protein with a suitable fluorescent agent, and When colloid electrophoresis is performed on the gel tray 30 , the user can directly observe the nucleic acid or protein bound by the fluorescent agent in the gel tray 30 irradiated by the light source through the transparent cover 40 and analyze the result. In this embodiment, the colloid medium carried by the gel tray 30 may be agarose gel (Agarose) or sodium dodecyl sulfate polyacrylamide gel (SDS-PAGE).

The light-transmitting cover 40 includes a filter 41 and an electric heating element 42. The electric heating element 42 is embedded in the filter 41. Accordingly, the electric heating element 42 can eliminate the light generated in the filter through heating. The mist on the sheet 41, the heating element 42 includes a power supply contact 421 and a heating wire 422, the power supply contact 421 is set on one side close to the filter 41, and the heating wire 422 is electrically connected to the power supply connection Point 421. In this embodiment, the heating wire 422 includes a peripheral portion 422a and a plurality of finger portions 422b, the peripheral portion 422a is formed around an edge of the filter 41, and the finger portions 422b are parallel to each other and spaced apart from each other. And extend inwardly from one side of the peripheral portion 422a in a single direction to the other side opposite to the side.

The optical filter 41 includes a non-transparent part embedded with the electric heating element 42 to block light or line of sight, and a transparent part complementary to the non-transparent part. With the above-mentioned structural design, an observation area 411 can be left on the optical filter 41 to provide a defogging function without blocking the user's sight line. As shown in the figure, the heating wire 422 is embedded in the filter 41 according to the geometric pattern of a plurality of fingers interspersed at intervals, which can evenly distribute heat to the entire filter 41 without blocking the user. Sight.

In one example, the filter 41 is a 580nm amber filter, which can remove the backlight from the light source (blue light source with a wavelength of 470nm±10nm) directed to the gel plate 30, and enhance the display of the light source A light source that excites a fluorescent agent bound to a nucleic acid or protein in a colloid.

Further, in this embodiment, the light source module 10 is electrically connected to the power supply module 50, the electrophoresis tank 20 is electrically connected to the light source module 10, and the electric heating element 42 of the transparent cover 40 is electrically connected to To the electrophoresis tank 20 , in other words, power is supplied from the power supply module 50 to the light source module 10 , the electrophoresis tank 20 and the heating element 42 of the transparent cover 40 . Accordingly, the present invention only needs the power supply module 50 to provide power to the light source module 10, the electrophoresis tank 20, and the electric heating element 42 of the light-transmitting cover 40, and does not need to separate multiple devices. Connect to the power supply equipment (such as battery module or mains) to play a role (that is, the light source module 10 generates light, the electrophoresis tank 20 performs electrophoresis and the heating element 42 eliminates the fog on the filter 41), This makes the electrophoresis device 1 lighter in size.

Referring to "Fig. 3", it is a partial exploded view of another perspective of an embodiment of the present invention. The power supply module 50 can be a battery module or be connected to a commercial power supply to provide power supply. Further, the power supply module 50 can include a convex portion 51 and a transformer regulator (not shown in the figure). The portion 51 protrudes toward the light source module 10 , and the transformer regulator provides various plugs to match the voltages of different countries. In addition, the base 11 of the light source module 10 also includes a concave portion 112, which is concavely formed toward a center of the light source module 10 and is arranged corresponding to the convex portion 51. When in use, the light source module 10 The concave portion 112 of the power supply module 50 is aligned with the convex portion 51 and placed above the convex portion 51, whereby the light source module 10 and the electrophoresis tank 20 stacked above the light source module 10 can be stabilized The ground is placed on the power module 50 and is located at the side of the power module 50 .

To sum up, the electrophoresis tank of the present invention is stacked on the light source module and illuminates the gel plate located on the transparent bottom wall through the light-emitting element, so that the electrophoresis can be observed in real time through the transparent cover. The efficacy of the result. Further, by setting the optical filter of the light-transmitting cover and the electric heating element, the mist generated on the light-transmitting cover during electrophoresis can be removed, avoiding the risk of electric shock caused by the user removing the mist manually , It can also solve the problem that the fog is easy to scrape off incompletely and cause the line of sight to be blocked. In addition, the electric heating element is directly embedded in the optical filter, and the power supply contact of the electric heating element is directly electrically connected to the electrophoresis tank without being externally connected to the power module, so that the power supply circuit is relatively simple, thereby reducing the risk of failure.

1: Electrophoresis equipment 10: Light source module 11: Base 111: fixed bump 112: concave part 12: Light emitting element 20: electrophoresis tank 21: side wall 21a: top surface 211: fixed groove 212: Boss 22: Translucent bottom wall 23: electrode group 24: space 30: Gel tray 40: Translucent cover 41: Optical filter 411: Observation area 42: Heating element 421: power supply contact 422: Heating wire 422a: peripheral part 422b: finger 50: Power module 51: convex part

[Fig. 1] is a three-dimensional combined view of an embodiment of the present invention.

[Fig. 2] is an exploded view of an embodiment of the present invention.

[Fig. 3] is a partial exploded view of another perspective of an embodiment of the present invention.

1: Electrophoresis equipment

10: Light source module

20: electrophoresis tank

40: Translucent cover

50: Power module

Claims (8)

An electrophoresis device with defogging function, comprising: A light source module, including a base and a light-emitting element fixed on the base, the light-emitting element emits a light source upward; An electrophoresis tank stacked on the light source module, the electrophoresis tank includes a surrounding side wall, a light-transmitting bottom wall receiving the light source, and a pair of electrode groups, the light-transmitting bottom wall and the side wall jointly define a space , the electrode group provides an electric field in the space; a gel plate, arranged on the light-transmitting bottom wall and located in the space; A light-transmitting cover, which can be opened and closed on the electrophoresis tank, the light-transmitting cover includes a filter and an electric heating element embedded in the filter; and A power supply module is arranged on one side of the light source module and is electrically connected to the light source module, the electrophoresis tank and the electric heating element. The electrophoretic device as claimed in claim 1, wherein the base of the light source module includes two fixing protrusions extending upward. The electrophoresis device as claimed in claim 2, wherein the side wall of the electrophoresis tank includes two fixing grooves corresponding to the fixing protrusions. The electrophoretic device as claimed in claim 1, wherein the light emitting element is an LED light bulb. The electrophoresis device according to claim 1, wherein the electric heating element includes a power supply contact and an electric heating wire electrically connected to the power supply contact. The electrophoretic device as described in claim 5, wherein the electric heating wire of the electric heating element includes a peripheral portion and a plurality of finger portions, the peripheral portion is formed around an edge of the filter, and the finger portion is formed from One side of the peripheral portion extends inwardly toward the other side opposite to the side. The electrophoretic device according to claim 1, wherein the optical filter includes a non-transparent part embedded with the electric heating element and a transparent part complementary to the non-transparent part. The electrophoresis device according to claim 1, wherein the light source module is electrically connected to the power supply module, the electrophoresis tank is electrically connected to the light source module, and the electric heating element of the transparent cover is electrically connected to the electrophoresis tank .

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