TWM549609U - Structure of artificial bone - Google Patents

Description

Artificial bone structure

The present invention relates to an artificial bone structure, and more particularly to an artificial bone structure comprising a tissue barrier film integrally formed with artificial bone.

Artificial Bone refers to an artificial biomaterial that can replace human bone or repair or reconstruct bone tissue defects. Artificial bone can be roughly classified into inorganic materials, organic materials and composite materials according to the structure and properties of the materials.

The advantage of inorganic materials is that they are biocompatible and have the disadvantage of poor mechanical properties. The most famous inorganic material used as artificial bone is bioceramic. Bioceramics can be further classified into four categories according to the type of tissue reaction produced by the interface between the implant and the host bone tissue: 1. Nearly inert crystalline bioceramics, 2. Porous ceramics, 3. Surface active ceramics, and 4. Absorbable ceramics. Among them, the chemical composition of the surface active ceramic is similar to that of the human bone tissue, and it has biological activity and can directly bind to the host bone tissue by means of chemical bonds. A representative example of a surface active ceramic is a hydroxyapatite (HAP) ceramic; the absorbable ceramic is gradually absorbed in the host and gradually replaced by the formed new bone, a representative example of which is tricalcium phosphate (TCP). ceramics. The organic material is extracted from animal connective tissue or skin, which is a specially chemically processed protein substance, and has a good osteogenic ability because it contains certain osteogenic factors. Organic materials include collagen, bone morphogenetic proteins, and various osteogenic factors. The composite material is a material containing two components of an organic material and an inorganic material. Composite artificial bone is mainly divided into calcium phosphate composite artificial Bone, polymer composite artificial bone, red bone marrow composite artificial bone, other kinds of composite artificial bone, the basic principle is to combine the material with bone conduction ability with bone-inducing ability such as bone growth factor, bone marrow tissue, etc. Composite artificial bones make them both osteoconductive and osteoinductive.

In the process of bone tissue reconstruction or repair, in addition to the use of the above-mentioned artificial bone, in order to avoid the invasion of the soft tissue around the defect site into the bone tissue reconstruction part, the soft tissue isolation membrane is usually used in the bone tissue reconstruction operation to block the soft tissue invasion, to give The bone tissue is rebuilt with sufficient space and time to facilitate the repair of bone tissue. Soft tissue isolating membranes can also be divided into in vivo absorbable soft tissue barriers and in vivo non-absorbable soft tissue barriers. Among them, the non-absorbable soft tissue isolation membrane in the body needs to undergo a second operation to remove the soft tissue isolation membrane after the bone tissue is repaired. Conversely, the use of an in vivo absorbable soft tissue barrier eliminates the need for a second surgical procedure to remove the soft tissue barrier. However, the in vivo absorbable soft tissue barrier film has the disadvantages of poor material strength, non-stitching, and easy breakage.

Figure 1 is a schematic view showing the implantation of artificial bone in the prior art. Reconstructing or repairing the bone tissue mainly comprises: cutting the covered tissue around the body to be reconstructed or repaired, implanting the artificial bone 13 into the site to be reconstructed or repaired 19, covering the soft tissue isolation preventing the soft tissue from invading the site to be reconstructed or repaired. The film 11 is fixed by stitching. Among them, since the artificial bone 13 has a smooth surface, it cannot be directly caught in the portion to be reconstructed or repaired.

In the prior art, in order to hold the artificial bone 13 in the to-be-reconstructed or repaired portion 19, the soft tissue separation membrane 11 is directly sutured to the portion to be reconstructed or repaired 19 according to the suturing characteristics of the soft tissue separation membrane 11, or is cut open. Covering the tissue to cover the soft tissue barrier film 11 and the artificial bone 13 and then suturing the cut coated tissue can prevent the artificial bone 13 from falling out of the portion 19 to be reconstructed or repaired. Further, since the artificial bone 13 and the soft tissue separation membrane 11 are separated from each other in the prior art, the soft tissue separation membrane 11 may be displaced after implantation, and the implantation process is complicated and complicated, and the pain and surgery of the patient are increased. the cost of.

In order to solve the above problems, the purpose of the present invention is to provide an artificial bone structure including a sawtooth assembly.

According to one of the purposes of the present invention, an artificial bone structure is proposed, comprising: an artificial bone body; a sawtooth component located on a surface of the artificial bone body; and an artificial bone body made of a biodegradable material and disposed on the non-serrated component thereon A soft tissue barrier on one side.

Preferably, the artificial bone body can be integrally formed with the soft tissue barrier film and/or the sawtooth component.

Preferably, the artificial bone body can be cylindrical, conical, angular or pyramidal.

Preferably, the sawtooth assembly can comprise a plurality of serrations.

Preferably, a plurality of serrations may be formed on the surface of the artificial bone body in one or more rows.

Preferably, each of the plurality of serrations may be cylindrical, conical, angular or pyramidal, or may have an anchor configuration, a sickle configuration, a star configuration or an umbrella configuration.

Preferably, the sawtooth assembly can comprise a sawtooth assembly body having a threaded structure or a concentric circular structure.

Preferably, at least a portion of the serration assembly body can be wavy.

Preferably, the serrations are formed on the body of the sawtooth assembly.

Preferably, the serrations may be cylindrical, conical, angular or pyramidal, or may have an anchor configuration, a sickle configuration, a star configuration or an umbrella configuration.

In the artificial bone structure of the present invention, the soft tissue separation membrane can be integrally formed on the top of the artificial bone, thereby preventing the soft tissue separation membrane from being displaced after implantation. In addition to the saw The tooth assembly, the artificial bone structure of the present invention can be tightly engaged in the site for bone tissue reconstruction, without the need to suture the soft tissue barrier or suture the incision of the coated tissue, thereby simplifying the surgical procedure and reducing the suffering of the patient The cost of surgery and the possibility of rupture of the soft tissue barrier.

11, 21 ‧ ‧ tissue isolation membrane

13‧‧‧Artificial bone

19‧‧‧The part to be reconstructed or repaired

20, 40‧‧‧ artificial bone structure

23‧‧‧ Artificial bone body

25‧‧‧Sawtooth components

27‧‧‧ side surface

42‧‧‧Sawtooth

44, 46‧‧‧Sawtooth component body

The above and other features and advantages will be described in more detail by reference to the appended drawings, which will be more

Fig. 1 is a schematic view showing the implantation of an artificial bone in the prior art.

Figure 2 is a cross-sectional view of an artificial bone structure in accordance with an embodiment of the present invention.

Fig. 3 is a schematic view of a saw tooth according to the present embodiment.

Figure 4 is a schematic illustration of an artificial bone structure in accordance with another embodiment of the present invention.

In order to understand the characteristics, content and advantages of this creation and the effects that can be achieved, the author will use the drawing in detail and explain the following in the form of the embodiment. The purpose of the drawing is only The use of the instructions and the accompanying manuals may not be true proportions and precise configurations after the implementation of the creations. Therefore, the proportions and configuration relationships of the attached drawings should not be interpreted or limited in the actual implementation scope.

The advantages, features, and technical methods of the present invention will be more readily understood by referring to the exemplary embodiments and the accompanying drawings, and the present invention may be implemented in various forms and should not be construed as limited thereto. The embodiments set forth herein, and vice versa, will provide a more thorough and complete and complete disclosure of the scope of the present invention, and the present invention will only be The scope of the patent application is defined.

Please refer to FIG. 2, which is a cross-sectional view of the artificial bone structure 20 according to the present creative embodiment. As shown, the artificial bone structure 20 includes a soft tissue barrier 21, an artificial bone body 23, and a sawtooth assembly 25. The artificial bone body 23 has a side surface 27 on which the serration assembly 25 can be integrally formed. The soft tissue separation membrane 21 can be integrally formed on the top of the artificial bone body 23, so the artificial bone structure 20 of the present invention can prevent the soft tissue separation membrane 21 from being displaced after implantation.

According to the embodiment of the present invention, the soft tissue separation film 21 can be cut into various suitable sizes and shapes and can be formed by biodegradable materials. The biodegradable materials can be classified into natural polymer materials and synthetic polymer materials according to their sources. Or a composite material of natural polymer materials and synthetic polymer materials. Examples of natural polymeric materials include, but are not limited to, Collagen, Chitin, Chitosan, Alginate, Hyaluronic acid, Cellulose ( Cellulosic materials), gelatin (Gelatin) and starch. Examples of synthetic polymeric materials include, but are not limited to, polyhydroxyalkanoates (PHA), polycaprolactone (PCL), polylactide (PLA), polylactic acid-glycolic acid copolymer (poly(lactic) -co-glycolic acid), PLGA), Polyglutamic acid (PGA). The material of the soft tissue separation membrane 21 is preferably collagen, PLA, PLGA, PGA, chitosan or any combination of the materials.

According to an embodiment of the present invention, the artificial bone body 23 may be formed of an inorganic material, an organic material, or a composite material of an organic material and an inorganic material. In addition, in order to allow the artificial bone structure 20 to support the required space and shape, the shape and size of the artificial bone body 23 are adjusted according to the portion where the bone tissue is to be reconstructed (ie, the portion 19 in FIG. 1), for example, artificial The shape of the bone body 23 may be cylindrical, conical, angular, or pyramidal, as shown in Fig. 2, but the present creation is not limited thereto. In an embodiment, the artificial bone body 23 may be formed of bioceramic, collagen or any combination of the above materials, preferably hydroxyapatite. A stone (HAP) ceramic, a tricalcium phosphate (TCP) ceramic, or a combination thereof. In another embodiment, the bioceramic forming the artificial bone body 23 can be bioglass, calcium sulfate or calcium carbonate.

The serrated assembly 25 can be formed from the same or a different material than the artificial bone body 23. For example, the serrated assembly 25 can be formed from bioceramics, collagen, or any combination of the above. The serration assembly 25 can be formed on the side surface 27 of the artificial bone body 23 in a row, a plurality of rows, a thread or a concentric structure. And although the sawtooth assembly 25 is shown in FIG. 2 to be formed on the surface of the artificial bone body in a row of three serrations, the present creation is not limited thereto. In an embodiment, the serrations 25 can be formed on the side surface 27 of the artificial bone body 23 by one or two serrations or three or more serrations per row. The number of serrations of each row can be the same or different and each The spacing between the rows of serrations may be the same or different from each other, as shown in Figure 2. The serrations may form an angle with the side surface 27 in the range of 30 to 135 degrees. For example, the serrations may form an angle of 135 degrees with the artificial bone side surface 27 as shown in FIG. When the angle formed between the serrations and the side surfaces 27 is too large or too small (greater than 135 degrees or less than 30 degrees), the artificial bone structure 20 may not be effectively fixed in the portion 19.

Fig. 3 is a schematic view of a saw tooth according to the present embodiment. The serrations forming the serration assembly 25 may be cylindrical, conical, angular or pyramidal, or may have an anchor configuration, a sickle configuration, a star configuration or an umbrella configuration, but the present creation is not limited thereto. The anchored structure as used herein refers to a sawtooth configuration whose surface comprises one or more protrusions, and the shape of the protrusion may be cylindrical, conical, angular, or pyramidal; the protrusions may be in the same or different directions Extending; and the protrusions may have the same or different protrusion lengths as shown in FIGS. 3(a) and 3(b). The star-shaped structure described herein refers to a sawtooth configuration in which the ends of the serrations or the raised ends of the serrations are split into at least two portions, and the at least two portions may have the same or different lengths, as shown in FIG. 3(c). Shown. The umbrella structure described herein refers to a sawtooth configuration in which the serrated end is a bevel gear or a spiral bevel gear, as shown in Fig. 3(d). The sickle-like structure described herein refers to the serrated end The portion has a zigzag configuration with a curved shape as shown in Fig. 3(e). The material used to form the protrusions may be bioceramics, collagen, or any combination of the above. The projections may be formed integrally with the serrations by the same or different materials as the serrations. In an embodiment, when the sawtooth assembly 25 includes a plurality of serrations, each of the serrations may be cylindrical, conical, angular, or pyramidal, or may have an anchor configuration, a sickle structure, a star configuration, or The umbrella configuration and each of the serrations may have the same or different lengths from each other.

By forming the serrated assembly 25, the artificial bone structure 20 of the present invention can be more securely and securely secured to the defect site via the serrated assembly 25. The artificial bone structure 20 of the present invention can eliminate the step of suturing the coated tissue to fix the artificial bone in the portion 19, and reduce the possibility of the soft tissue isolating membrane during the suture coating, thereby improving the bone tissue reconstruction. Effect. For example, the artificial bone structure 20 of the present invention only needs to cut the coated tissue around the defect portion, and then the artificial bone structure 20 is placed in the defect portion to firmly engage the artificial bone structure 20 to the defect portion. There is no need to further perform the fixation step of the artificial bone structure, for example, the subsequent suturing step. Because the artificial bone structure 20 does not fall out of the defect portion even if the coated tissue is seamlessly cut. In this way, the creation can achieve the purpose of simplifying the surgical procedure and reducing the suffering of the patient, the cost of the surgery, and the possibility of rupture of the soft tissue separator.

Figure 4 is a schematic illustration of an artificial bone structure 40 in accordance with another embodiment of the present invention. The artificial bone structure 40 is substantially identical to the artificial bone structure 20 of FIG. 2 except for the configuration of the sawtooth assembly, so only the sawtooth assembly will be described below. The sawtooth assembly of the artificial bone structure 40 of the present invention may further comprise a sawtooth assembly body. Wherein, the sawtooth assembly body may be a sawtooth assembly body 44 having a threaded structure as shown in FIG. 4(a) or a sawtooth assembly body 46 having a concentric circular structure as shown in FIG. 4(b). In an embodiment, the sawtooth assembly body 44 having a threaded structure and the sawtooth assembly body 46 having a concentric circular structure At least a portion may be wavy, and the wavy portions are overlapped with respect to the crest portions of the upper and lower layers, as shown in Figs. 4(c) and 4(d). In another embodiment, the undulating portions are staggered at the crest portions of the upper and lower layers. One or more of the aforementioned serrations may be formed on a surface or side of the sawtooth assembly body, wherein the serrations may be cylindrical, conical, angular or pyramidal as described above, or may have an anchor configuration, a sickle-like configuration , star-shaped structure or umbrella structure. The serrations may protrude from the surface or sides of the serration assembly body at different angles and with different lengths. Specifically, taking the sawtooth assembly including the sawtooth assembly body 44 having a threaded structure as an example, one or more saw teeth 42 may be formed on the sawtooth assembly body 44 as shown in FIGS. 4(e) and 4(f). On the surface or on the side. When the serration assembly includes a plurality of serrations 42, the serrations 42 can have the same or different shapes and/or configurations from each other. The material used to form the serrations 42 can be bioceramics, collagen, or any combination of the above. The serrations 42 may be integrally formed with the serration assembly body 44 from the same or different materials as the serration assembly body 44.

By forming a sawtooth assembly comprising a sawtooth assembly body and one or more serrations, the artificial bone structure 40 of the present invention can be more securely and securely secured to the defect site via the sawtooth assembly. The artificial bone structure 40 of the present invention can eliminate the step of suturing the coated tissue to fix the artificial bone in the site to be reconstructed or repaired, thereby reducing the possibility of the soft tissue isolation membrane rupturing during the suture coating tissue, thereby improving The effect of bone tissue reconstruction. For example, the artificial bone structure 40 of the present invention only needs to cut the coated tissue around the defect portion, and then the artificial bone structure 40 is placed in the defect portion to firmly engage the artificial bone structure 40 to the defect portion. There is no need to further perform the fixation step of the artificial bone structure, for example, the subsequent suturing step. Because the artificial bone structure 40 does not fall out of the defect portion even if the coated tissue is seamlessly cut. In this way, the creation can achieve the purpose of simplifying the surgical procedure and reducing the suffering of the patient, the cost of the surgery, and the possibility of rupture of the soft tissue separator.

In summary, the artificial bone structure of the present invention has the characteristics that the soft tissue isolation membrane and the artificial bone are integrally formed, and the artificial bone structure of the present invention further has a sawtooth component on the artificial bone. Therefore, the soft tissue barrier film is not displaced after implantation, and the artificial bone structure of the present invention can be firmly and stably fixed to the defect portion through various kinds of sawtooth components. Therefore, when the artificial bone structure of the present embodiment is used in the reconstruction or repair process of the bone tissue, it is only necessary to first cut the coated tissue around the defect site and fill the artificial bone into the site to reconstruct or repair the bone tissue. The artificial bone structure of the present invention can prevent the soft tissue separation membrane from shifting and fixing the artificial bone after implantation in a seamless step, thereby simplifying the surgical procedure, reducing the cost, reducing the pain of the patient and reducing the breakage of the soft tissue separation membrane.

The above is intended to be illustrative only and not limiting. Any equivalent modifications or alterations to the spirit and scope of this creation shall be included in the scope of the appended patent application.

20‧‧‧ Artificial bone structure

21‧‧‧ Tissue isolating membrane

23‧‧‧ Artificial bone body

25‧‧‧Sawtooth components

27‧‧‧ side surface

Claims (12)

An artificial bone structure comprising: an artificial bone body; a sawtooth assembly on a surface of the artificial bone body; and a soft tissue isolation membrane made of a biodegradable material and disposed on one side of the artificial bone body on. The artificial bone structure of claim 1, wherein the artificial bone system is integrally formed with the soft tissue barrier film. The artificial bone structure of claim 2, wherein the artificial bone system is integrally formed with the sawtooth assembly. The artificial bone structure of claim 1, wherein the artificial bone system is integrally formed with the sawtooth assembly. The artificial bone structure of claim 1, wherein the shape of the artificial bone body comprises a cylindrical shape, a conical shape, a prismatic shape, or a pyramidal shape. The artificial bone structure of claim 1, wherein the sawtooth assembly comprises a plurality of serrations. The artificial bone structure of claim 6, wherein the plurality of serrations are formed on the surface of the artificial bone body in one or more rows. The artificial bone structure according to claim 6, wherein each of the plurality of serrations is cylindrical, conical, angular or pyramidal, or has an anchor structure, a sickle structure, a star structure or an umbrella structure. . The artificial bone structure of claim 1, wherein the sawtooth assembly comprises a sawtooth assembly body having a threaded structure or a concentric circular structure. The artificial bone structure of claim 9, wherein at least a portion of the body of the sawtooth assembly is wavy. The artificial bone structure of claim 9, wherein the sawtooth assembly has one or more serrations thereon. The artificial bone structure of claim 9, wherein the one or more serrations are cylindrical, conical, angular or pyramidal, or have an anchor structure, a sickle structure, a star shape or an umbrella shape. structure.