TWM535807U - Detecting device - Google Patents

Abstract

The invention discloses a detecting device includes an image capture module, a light-source module and a filter module. The image capture module has a camera. The light-source module is disposed adjacent to the image capture module. The filter module has a frame body and a first filter located at the frame body. The frame body is swung at least between a first position and a second position. When the frame body is located at the first position, the first filter is located at an image capture direction of the camera. The camera captures at least a first image through the first filter. When the frame body is located at the second position, the camera captures at least a second image.

Description

Testing device

The present invention relates to a detecting device, and more particularly to a detecting device that performs detection using an autofluorescent image.

According to the death statistics of the Ministry of Health and Welfare in 2012, malignant tumors are the leading cause of death in Taiwan for 32 consecutive years, and the top 5 cancers with the largest number of cancers and deaths are colorectal cancer, liver cancer, lung cancer, breast cancer, and oral cancer. (including oropharynx, hypopharynx). Taking oral cancer as an example, it is obviously related to the habit of Taiwanese chewing betel nuts and smoking. Oral cancer occurs in the cheek mucosa and lower gums of the betel nut chews. Patients often wait until the symptoms of pain, swelling or facial deformation have entered the advanced stage, and the five-year survival rate is reduced by more than half compared with the early cancer. Early diagnosis and appropriate treatment in the early stages of oral cancer can reduce mortality, so early screening for oral cancer is an important issue.

At present, common methods for screening cancer include doctor's visual inspection or palpation, pathological biopsy, etc. The more accurate diagnosis is pathological biopsy. However, pathological biopsy is an invasive examination, resulting in the formation of wounds in patients, and this The process can also cause the patient's psychological burden, fear and physical pain, and the results must be carefully interpreted and analyzed by a cancer specialist pathologist to determine whether the tumor is benign or malignant.

Another commonly used non-invasive cancer screening method is less likely to cause discomfort to the patient than invasive pathological biopsy. Non-invasive oral cancer screening on the market includes brush tissue examination, Toluidin Blue special staining, and autofluorescence imaging. Among them, brush tissue examination can only screen abnormal growth of oral epithelial tissue, while aniline blue special staining examination takes at least 5 minutes to wait for oral tissue staining. Autofluorescence imaging has no defects in the above two non-invasive oral cancer screening, and has a large screening area, and also has the advantage of instant display. Therefore, it has become one of the important research topics in the medical field.

The purpose of this creation is to provide a detection device that can perform non-invasive cancer screening using autofluorescence images to provide a basis for medical personnel diagnosis.

The present invention provides a detecting device comprising an image capturing module, a light source module and a filter module. The image capture module has a lens. The light source module is adjacent to the image capturing module. The filter module has a frame and a first filter disposed on the frame, and the frame swings between the at least one first position and the second position. Wherein, when the frame is in the first position, the first filter is located in an image capturing direction of the lens, and the lens captures at least one first image through the first filter, when the frame is in the second position, The lens captures at least one second image.

In an embodiment of the present invention, the filter module further has an opening on the frame, and the opening is located in the image capturing direction of the lens, and the lens captures the second image through the opening. Wherein, when the opening is located in the image capturing direction of the lens, the second image captured by the lens is a natural light image.

In an embodiment of the present invention, at least a portion of the filter module is located between the image capture module and the light source module. In addition, the first filter and the opening are substantially in the same swing plane, and the image capturing direction of the lens is substantially perpendicular to the swing plane. In addition, the frame body has a point, and the fulcrum is located outside the center of gravity of the filter module, and is driven by the fulcrum to drive the frame body to reciprocate.

In an embodiment of the present invention, the light source module has a first light source and a second light source. When the lens captures the first image through the first filter, the first light source is in a light-emitting state; when the lens is captured through the opening In the second image, the second light source is in a light-emitting state. The first light source includes at least one blue light emitting diode or at least one ultraviolet light emitting diode, and the second light source includes at least one white light emitting diode.

In an embodiment of the present invention, the filter module further has a second filter, and the second filter is located on the frame. In addition, the frame body further has a third position, and the frame body is driven to swing between the first position, the second position and the third position, so when the frame body is in the third position, the second filter is located In the image capturing direction of the lens, the lens captures at least one third image through the second filter.

In an embodiment of the present invention, the light source module has a first light source, a second light source, and a third light source. When the lens captures the first image through the first filter, the first light source is in a light-emitting state; When the lens captures the second image through the opening, the second light source is in a light-emitting state, and when the lens captures the third image through the second filter, the third light source is in a light-emitting state.

In an embodiment of the present invention, the detecting device further has a grip G, and the image capturing direction of the lens is at an angle of between 135 and 180 degrees with the grip G.

In one embodiment of the present invention, the detecting device is a hand-held oral detecting device, and the light source module excites the target to generate a fluorescent light.

As described above, in the detecting device of the present invention, the first filter of the filter module is located on the frame, and the frame is swingable between at least the first position and the second position. Wherein, when the frame is in the first position, the first filter is located in the image capturing direction of the lens, and the lens can capture at least one first image through the first filter; and when the frame is in the second position At the time, the lens can capture at least one second image without a filter (ie, natural light). Therefore, the detection device of the present invention uses a self-fluorescent image for non-invasive cancer screening, and the first image and the second image respectively obtained by the first filter and the non-filter can be used. The medical staff compares the images of natural light with the images obtained through the filters, thereby improving the accuracy of clinical screening for cancer screening and judgment.

Hereinafter, a detecting apparatus according to a preferred embodiment of the present invention will be described with reference to the related drawings, in which the same elements will be described with the same reference numerals. The illustrations of all the implementations of this creation are merely illustrative and do not represent true dimensions and proportions.

The human body itself has many light-sensitive substances (Fluorochrome), which emit different fluorescent light when illuminated by light, which is the self-fluorescent property. The presence of abnormal tissue can be identified by using different autofluorescence characteristics of abnormal tissue and surrounding normal tissue. The creation of the detection device is to use non-invasive abnormal tissue (cancer) screening by using autofluorescence images, thereby providing a basis for medical personnel diagnosis.

Please refer to FIG. 1 and FIG. 2 , which are respectively a schematic diagram and a schematic exploded view of a detecting device 1 according to a preferred embodiment of the present invention. The detecting device 1 includes an image capturing module 11 , a light source module 12 , and a filter module 13 . In addition, the detecting device 1 of the embodiment further includes a first housing 14 , a second housing 15 , a control circuit board 16 and a uniform energy switch 17 .

The detecting device 1 is used for detecting a target, such as human tissue, such as, but not limited to, oral tissue of a human body. The detecting device 1 of the embodiment is a hand-held oral detecting device, which allows the medical staff to carry the detecting device 1 into the patient's mouth and use the self-fluorescent image of the patient to perform an immediate non-invasive oral abnormality. Tissue (cancer) screening. Of course, in different embodiments, the detecting device 1 can also be a non-handheld non-invasive detecting device, and can detect tissues at other locations, for example, detecting whether a skin has a cancerous lesion or the like, and the creation is not limited.

The first housing 14 and the second housing 15 are combined with each other to form an accommodation space, such as but not limited to being combined by snapping or locking, or in other suitable combinations. Wherein, a plurality of engaging seats or locking seats are disposed in the accommodating space, thereby accommodating and fixing the image capturing module 11, the light source module 12, the filter module 13, the control circuit board 16 and the enabling switch 17 and other components. The image capturing module 11 , the light source module 12 and the enabling switch 17 are electrically connected to the control circuit board 16 respectively to be controlled by a processor 161 , a circuit and a component disposed on the control circuit board 16 . The processor 161 can be a core controller of the detection device 1, for example, can include at least one central processing unit (CPU). In addition, a memory module or a transmission interface or the like may be disposed on the control circuit board 16. The memory module is, for example, a memory or a secure digital memory card. The transmission interface can be, for example but not limited to, a Universal Serial Bus (USB). In addition, the first housing 14 and the second housing 15 can be combined to form a grip G for the medical staff to hold.

Referring to FIG. 2 and FIG. 3A to FIG. 3C , detailed technical contents of the image capturing module 11 , the light source module 12 , and the filter module 13 are described in detail. 3A to 3C are respectively relative schematic views of the image capturing module 11, the light source module 12 and the filter module 13 in the detecting device 1 of FIG.

The image capturing module 11 has a lens 111, such as a Charge-coupled Device (CCD), a Complementary Metal-Oxide-Semiconductor (CMOS) or other suitable photosensitive element. In some embodiments, the image capturing module 11 may also include components such as an aperture, a shutter, and the like.

The light source module 12 is adjacent to the image capturing module 11 and emits light to excite the target to generate a fluorescent light. The light source module 12 can provide a white light source (natural light), a UV wavelength (wavelength of, for example, 375 nm), a blue light wavelength (wavelength of, for example, 460 nm), or a light source of other wavelengths. In this embodiment, the light source module 12 includes a plurality of light emitting diodes (LEDs) 121 and includes at least one white light emitting diode, at least one blue light emitting diode, and at least one ultraviolet light emitting light. Polar body to emit white light, UV light or blue light, respectively. In other embodiments, the light source module 12 can also include other suitable light sources. In addition, in addition to the LEDs 121, the light source module 12 further has a substrate 122. The LEDs 121 are disposed on the substrate 122, and the substrate 122 has a through hole 123 therein.

The filter module 13 has a frame 131, a first filter 132 and an opening O. The first filter 132 and the opening O are located on the frame 131, and the frame 131 can be at least a first position. Swing between P1 and a second position P2. As shown in FIG. 3A, when the frame 131 is swung and located at the first position P1, the first filter 132 is located in the image capturing direction D of the lens 111 (the image capturing direction D is substantially the same as the direction viewed by the medical staff). And the lens 111 can capture at least one first image through the first filter 132; in addition, as shown in FIG. 3B, when the frame 131 is swung to be in the second position P2, the opening O is located in the image of the lens 111. The direction D is captured, and the lens 111 can capture at least one second image through the opening O.

In addition to the first filter 132 and the opening O, the filter module 13 of the present embodiment further has a second filter 133, and the second filter 133 is also located on the frame 131. As shown in FIG. 3C, the frame body 131 has a third position P3 when it is swung, and the frame body 131 can be swung between the first position P1, the second position P2 and the third position P3. When the frame 131 is swung and located at the third position P3, the second filter 133 is located in the image capturing direction D of the lens 111, and the lens 111 can capture at least one third through the second filter 133. image. The openings O are adjacent to the first filter 132 and the second filter 133, respectively, and the first filter 132, the opening O and the second filter 133 are substantially in the same swing plane, and the lens 111 is The image capturing direction D is substantially perpendicular to the oscillating plane.

In this embodiment, the arrangement of the first filter 132, the opening O, and the second filter 133 on the frame 131 is not on the same straight line (the geometric center points of the three are not in a straight line), and the frame body The first filter 132, the opening O, and the second filter 133 on the 131 are substantially on the same plane (the plane is a plane formed by the frame body 131 itself). Further, the opening O is located between the first filter 132 and the second filter 133. However, in different embodiments, the first filter 132 may be located between the opening O and the second filter 133, or the second filter 133 may be located between the opening O and the first filter 132. This creation is not limited.

In addition, the opening O of the frame 131 of the present embodiment is substantially triangular or fan-shaped, and the first filter 132 and the second filter 133 are substantially rectangular, but not limited thereto, in different embodiments. The opening O may also be trapezoidal or other shape, and the first filter 132 and the second filter 133 may have other shapes, such as trapezoidal, circular or other shapes. In various embodiments, as shown in FIG. 4A, the opening O on the frame body 131a is an open V-shape without a bezel.

In addition, as shown in FIG. 3A , the filter module 13 of the embodiment further has a motor 134 , two gears 135 , 136 and a rotating shaft 137 . The motor 134 is, for example but not limited to, a stepper motor or a servo motor, and is electrically coupled to the processor 161 of the control circuit board 16 to be controlled by the processor 161. The gear 135 is mounted on the rotating shaft of the motor 134 and meshes with the gear 136. The two ends of the rotating shaft 137 are respectively connected to the gear 136 and a point 1311 of the frame body 131. Since the frame body 131 of the present embodiment is also substantially fan-shaped, the fulcrum 1311 of the frame body 131 is located outside the center of gravity of the filter module 13, so that the rotating shaft 137 can drive the frame body 131 to swing back and forth by the fulcrum 1311. The frame 131 can be controlled to be swayed between the first position P1 and the third position P3, or the frame 131 can be restricted to the first position P1 and the third by, for example, a limit switch (not shown). Swing between positions P3 (the above-mentioned limit switch can also be used as the adjustment position). In addition, since the shape of the frame body 131 is substantially fan-shaped, the volume of the detecting device 1 can also be reduced, which is convenient for the medical staff to use and extend into the oral cavity of the patient.

Referring to FIG. 2 again, the enable switch 17 is disposed on the control circuit board 16 and protrudes through the first housing 14 to the outside, and activates the switch 17 and the processor 161 and the circuit on the control circuit board 16. Sexual connection. In some embodiments, after the enable switch 17 is pressed, the processor 161 simultaneously controls the rotation of the motor 134 to link the frame 131, and controls the corresponding light source of the light source module 12 to emit light, and the lens of the image capturing module 11 is made. 111, the image is acquired, the processor 161 obtains the image, and then performs image processing and calculation; or, in different embodiments, after the enable switch 17 is pressed, the processor 161 controls the motor 134 to rotate and interlock the frame 131. When the body 131 is swung to trigger, for example, a limit switch, the light source corresponding to the light source module 12 is controlled to emit light, and the lens 111 of the image capturing module 11 is used to acquire an image. The processor 161 obtains the image and performs image processing and calculation. There is no limit to the creation. The image captured by the lens 111 can be first stored in the memory on the control circuit board 16, and then transmitted to another electronic device (for example, a computer) through the transmission interface on the control circuit board 16, and the electronic device can display These captured images are for medical personnel to check for abnormal tissue in the mouth.

In addition, at least a part of the filter module 13 is located between the image capturing module 11 and the light source module 12 . For example, in FIG. 3A , the first filter 132 on the frame 131 of the filter module 13 is located between the lens 111 of the image capturing module 11 and the light source module 12 . In addition, the lens 111 of the image capturing module 11 of the embodiment is located between the motor 134 and the frame 131, and the frame 131 is located between the lens 111 and the light source module 12, and the image capturing direction D of the lens 111 The first housing 14 and the second housing 15 can be formed by the opening O of the frame 131, or the first filter 132 or the second filter 133, and the through hole 123 of the light source module 12, and A notch H at the front end of the device. Therefore, when the light emitted by the light-emitting diode 121 of the light source module 12 is irradiated to the target, the fluorescent or reflected light emitted by the target may be the notch H, the through hole 123, the opening O on the frame 131, or the first filter. The light sheet 132 or the second color filter 133 is received by the lens 111, and processed by the processor 161 of the control circuit board 16 to generate an image. In this embodiment, the medical staff can hold the grip G to extend the front end (notch H) of the detecting device 1 into the mouth of the patient. In order to make the medical staff feel good and easy to operate when holding the detecting device 1, the angle between the image capturing direction D of the lens 111 and the grip G is preferably between 135 and 180 degrees.

In general, when there is a tumor in the mouth, the blood vessels around the tumor will proliferate, causing hypoxia and congestion in nearby tissues. Since the absorption coefficient of blood for autofluorescence is higher at a wavelength ranging from about 200 nanometers (nm) to about 600 nm, autofluorescence excited in this band is absorbed by blood, resulting in fluorescence near the tumor. dark. In addition, studies have shown that in the absence of oxygen or tumors in the body, the concentration of nicotine indoleamine adenine dinucleotide (NADH) will increase and the concentration of flavin adenine dinucleotide (FAD) will Falling, in this embodiment, the light sources of different wavelengths are used to excite NADH and FAD, respectively. The following is an example of how to take fluorescent images of different wavelengths.

In this embodiment, when the enable switch 17 is pressed to rotate the motor 134, the gears 135, 136 also rotate to drive the rotating shaft 137 to rotate, so that the frame 131 is in the first position P1, the second position P2 and the first The three positions P2 are swung to make the first filter 131 (green, corresponding to the first position P1), or the opening O (corresponding to the second position P2), or the second filter 133 on the frame 131. (blue, corresponding to the third position P3) is located in the image capturing direction D of the lens 111. The operation of the first filter 132 corresponds to the fluorescence excited by the blue light source (referred to as the first light source of the light source module 12, including at least one blue light emitting diode), and the opening O corresponds to The white light reflected by the white light source (referred to herein as the second light source of the light source module 12, including at least one white light emitting diode), and the second filter 133 is operated corresponding to the UV light source (herein referred to as The third light source of the light source module 12 includes the fluorescent light excited by the at least one ultraviolet light emitting diode.

Specifically, the LED 121 that provides the blue light source in the light source module 12 of the embodiment corresponds to the first filter 132 (green), the LED that provides the white light source corresponds to the opening O, and the LED 121 of the UV light source is Corresponding to the second filter 133 (blue). However, in different embodiments, the LED 121 providing the blue light source in the light source module 12 may correspond to the second filter 133 (green), and the LED 121 providing the UV light source in the light source module 12 may correspond to the first Filter 132 (blue), this creation is not limited. In addition, since the frame 131 is disposed between the light source module 12 and the lens 111, light entering from the notch H and the through hole 123 passes through the first filter 132, or the opening O, or the second filter 133. It is received by the image capturing module 11. In addition, the first filter 132, one of the opening O and the second filter 133 are disposed between the through hole 123 and the lens 111 of the image capturing module 11 through the gears 135 and 136.

In addition, in different embodiments, the frame body 131 can also rotate around the fulcrum 1311 to rotate the first filter 132, the opening O and the second filter 133 to the fulcrum 1311. side. As shown in FIG. 4B , it is a schematic diagram of the image capturing module 11 , the light source module 12 and the filter module 13 in the detecting device of different embodiments of the present invention.

In this embodiment, since the frame 131 is rotated completely around the fulcrum 1311, the frame 131 is not located in the image capturing direction D of the lens 111, and the position can be regarded as the second At position P2, the image of this position (still referred to as the second position P2) is also captured by the lens 111, and the image can be regarded as the second image described above. Therefore, in this embodiment, when the second image is captured by the lens 111, the first filter 132 and the second filter 133 on the frame 131 are not passed, and the opening O on the frame 131 is not used. But a second image of natural light can also be captured.

When the enable switch 17 is enabled, as shown in FIG. 3A, the processor 161 drives the motor 134 to swing the frame 131 to the first position P1, so that the first filter 132 is located in the through hole 123 and the image. The light source between the modules 11 and the at least one light-emitting diode 121 (first light source) of the light source module 12 is provided to provide a blue light source (where the second light source and the third light source do not emit light) to illuminate the target tissue. The processor 161 simultaneously controls the lens 111 of the image capturing module 11 to capture the first image emitted by the target via the first filter 132. Next, as shown in FIG. 3B, the processor 161 drives the motor 134 to swing the frame 131 to the second position P2, so that the opening O is located between the through hole 123 and the image capturing module 11, and drives the light source module 12 The at least one light emitting diode 121 (second light source) provides a light source of white light wavelength (when the first light source and the third light source do not emit light), and the processor 161 simultaneously controls the lens 111 of the image capturing module 11 The second reflected image of the target is captured via the opening O. Then, as shown in FIG. 3C, the processor 161 further drives the motor 134 to swing the frame 131 to the third position P3, so that the second filter 133 is located between the through hole 123 and the image capturing module 11, and At least one light emitting diode 121 (third light source) driving the light source module 12 supplies a light source of a UV light wavelength (in which case the first light source and the second light source do not emit light), and the processor 161 simultaneously controls image capturing. The lens 111 of the module 11 captures the third image emitted by the target via the second filter 133.

Therefore, in the present embodiment, when the enable switch 17 is pressed, the detecting device 1 automatically acquires three images. However, the order in which the images are acquired is only an example, and the creation does not limit the order in which images are obtained. Alternatively, the user can also select images to capture those wavelengths through a number of additional buttons, switches, and the like. The first image described above can be used to indicate the concentration of the FAD, the third image can be used to indicate the concentration of the NADH, and the second image is the image reflected by the tissue illuminated by the white light. Therefore, the second image can be provided to the medical staff to compare the first image and the third image obtained through the filter, thereby increasing the accuracy of the judgment.

In addition, it is assumed here that the first grayscale value of a certain pixel in the first image is a second grayscale value paired to a certain pixel in the third image. In some embodiments, the processor 161 may also divide the first grayscale value by the sum of the first grayscale value and the second grayscale value to obtain a ratio, which may be used to determine whether a tumor is present. In other words, if the first gray scale value is marked as FAD and the second gray scale value is marked as NADH, the calculated ratio can be written as the following equation (1): FAD / (FAD + NADH) ... (1 ).

In other embodiments, the above ratio may be combined with other features to become a feature vector. For example, the heterogeneity of the oral image can be regarded as an element in the feature vector, and the heterogeneity can be the variation of the grayscale value of the pixel, the entropy value, etc., and the creation is not limited thereto. In addition, in some embodiments, a plurality of sample images of the oral cavity may be collected in advance, and the feature vectors are captured for each sample image, and the feature vectors may be subjected to a machine learning algorithm to obtain a training model, and then tested. The processor 161 can extract the same feature vector from the current image, and determine whether there is a tumor based on the feature vector and the training model. This creation does not limit what learning algorithms are used. Moreover, in some embodiments, the processor 161 can also generate a confidence value based on the machine learning algorithm used in determining whether there is a tumor, thereby allowing the user to know how much confidence there is/without a tumor. .

In summary, in the detecting device of the present invention, the first filter of the filter module is located on the frame body, and the frame body can swing between at least the first position and the second position. Wherein, when the frame is in the first position, the first filter is located in the image capturing direction of the lens, and the lens can capture at least one first image through the first filter; and when the frame is in the second position At the time, the lens can capture at least one second image without a filter (ie, natural light). Therefore, the detection device of the present invention uses a self-fluorescent image for non-invasive cancer screening, and the first image and the second image respectively obtained by the first filter and the non-filter can be used. The medical staff compares the images of natural light with the images obtained through the filters, thereby improving the accuracy of clinical screening for cancer screening and judgment.

The above is intended to be illustrative only and not limiting. Any equivalent modifications or alterations to the spirit and scope of this creation shall be included in the scope of the appended patent application.

1‧‧‧Detection device
11‧‧‧Image capture module
111‧‧‧ lens
12‧‧‧Light source module
121‧‧‧Lighting diode
122‧‧‧Substrate
123‧‧‧through hole
13‧‧‧Filter module
131, 131a‧‧‧ frame
1311‧‧‧ pivot
132‧‧‧First filter
133‧‧‧Second filter
134‧‧‧ motor
135, 136‧‧‧ gears
137‧‧‧ shaft
14‧‧‧First housing
15‧‧‧ second housing
16‧‧‧Control circuit board
161‧‧‧ processor
17‧‧‧Enable switch
D‧‧‧Image capture direction
G‧‧‧ grip
H‧‧‧ gap
O‧‧‧ openings
P1‧‧‧ first position
P2‧‧‧ second position
P3‧‧‧ third position

FIG. 1 and FIG. 2 are respectively a schematic diagram and a schematic exploded view of a detecting apparatus according to a preferred embodiment of the present invention. 3A to 3C are respectively relative schematic views of the image capturing module, the light source module and the filter module in the detecting device of FIG. 2 . Figure 4A is another schematic view of the frame. 4B is a schematic diagram of the image capturing module, the light source module and the filter module in the detecting device according to different embodiments of the present invention.

11‧‧‧Image capture module

111‧‧‧ lens

12‧‧‧Light source module

121‧‧‧Lighting diode

122‧‧‧Substrate

123‧‧‧through hole

13‧‧‧Filter module

131‧‧‧ ‧ body

1311‧‧‧ pivot

132‧‧‧First filter

133‧‧‧Second filter

134‧‧‧ motor

135, 136‧‧‧ gears

137‧‧‧ shaft

D‧‧‧Image capture direction

O‧‧‧ openings

P1‧‧‧ first position

Claims (13)

A detecting device for detecting a target, the detecting device comprising: an image capturing module having a lens; a light source module adjacent to the image capturing module; and a filter module having a The frame body and a first filter are located on the frame body, and the frame body is swung between at least a first position and a second position; wherein, when the frame body is located at the first position, the first filter The light film is located in an image capturing direction of the lens, and the lens captures at least one first image through the first filter. When the frame is in the second position, the lens captures at least one second image. . The detecting device of claim 1, wherein the filter module further has an opening on the frame, and the opening is located in the image capturing direction of the lens, and the lens is captured through the opening The second image. The detecting device of claim 2, wherein the second image captured by the lens is a natural light image when the opening is in the image capturing direction of the lens. The detecting device of claim 2, wherein the filter module further has a second filter, the second filter being located in the frame. The detecting device of claim 4, wherein the frame body further has a third position, the frame body being driven to swing between the first position, the second position and the third position, when When the frame is in the third position, the second filter is located in the image capturing direction of the lens, and the lens captures at least one third image through the second filter. The detecting device of claim 5, wherein the light source module has a first light source, a second light source, and a third light source, and the lens captures the first image through the first filter The first light source is in a light-emitting state. When the lens captures the second image through the opening, the second light source is in a light-emitting state. When the lens captures the third image through the second filter, The third light source is in a light emitting state. The detecting device of claim 2, wherein the first filter and the opening are substantially in the same swinging plane, and the image capturing direction of the lens is substantially perpendicular to the swinging plane. The detecting device of claim 2, wherein the light source module has a first light source and a second light source, and when the lens captures the first image through the first filter, the first The light source is in a light-emitting state, and when the lens captures the second image through the opening, the second light source is in a light-emitting state. The detecting device of claim 8, wherein the first light source comprises at least one blue light emitting diode or at least one ultraviolet light emitting diode, and the second light source comprises at least one white light emitting diode. The detecting device of claim 1, wherein the detecting device further has a grip, and the image capturing direction of the lens is between 135 degrees and 180 degrees with the grip. The detecting device of claim 1, wherein at least a portion of the filter module is located between the image capturing module and the light source module. The detecting device of claim 1, wherein the frame body has a point on the outer side of the center of gravity of the filter module, and the fulcrum is used to drive the frame body to reciprocate. The detecting device of claim 1, wherein the detecting device is a hand-held oral detecting device, and the light source module excites the target to generate a fluorescent light.