TWM529517U - Heating dressing material structure - Google Patents

Heating dressing material structure Download PDF

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TWM529517U
TWM529517U TW105208712U TW105208712U TWM529517U TW M529517 U TWM529517 U TW M529517U TW 105208712 U TW105208712 U TW 105208712U TW 105208712 U TW105208712 U TW 105208712U TW M529517 U TWM529517 U TW M529517U
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Taiwan
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semi
solid gel
concentration
gel layer
heat
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TW105208712U
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Chinese (zh)
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羅婉榕
郭家宏
李邦浩
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久原生醫有限公司
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Priority to TW105208712U priority Critical patent/TWM529517U/en
Publication of TWM529517U publication Critical patent/TWM529517U/en
Priority to JP2017000729U priority patent/JP3210251U/en

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  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

A heating dressing material structure is provided, including a thin heating pad with a thickness smaller than 5 mm; and a semi-solid gel layer having a first surface and a second surface. The first surface of the semi-solid gel layer is attached to the thin heating pad. In addition, the semi-solid gel layer comprises a skin external composition, which having a first concentration at the second surface of the semi-solid gel layer and a second concentration at the first surface of the semi-solid gel layer, and the first concentration is larger than the second concentration.

Description

發熱敷材結構Heated material structure

本創作係關於一種發熱敷材結構,特別是結合薄型發熱體與半固體凝膠層,且此半固體凝膠層塗佈有具濃度梯度之皮膚外用劑之發熱敷材結構。The present invention relates to a heat-cured material structure, in particular, a thin heat-generating body and a semi-solid gel layer, and the semi-solid gel layer is coated with a heat-producing structure of a skin external preparation having a concentration gradient.

一般而言,敷材可區分為溼式敷材及乾式敷材。常見的溼式敷材有面膜,其主要結構大多為僅使用單層支持布料(例如不織布),加以「浸泡」皮膚外用劑(例如玻尿酸、膠原蛋白等),使用者可直接將單層布料敷貼在臉上;較為常見之乾式敷材則有外用貼布,係直接在支持布料上「塗佈」皮膚外用劑之外,且另塗佈一層黏著層,使貼布可牢固黏貼在目標部位上。In general, the dressing can be classified into a wet dressing and a dry dressing. Common wet dressings have masks. Most of the main structures are only using a single layer of supporting fabric (for example, non-woven fabric), and "soaking" skin external preparations (such as hyaluronic acid, collagen, etc.), users can directly apply a single layer of fabric. Stick to the face; the more common dry dressings have external patches, which are directly applied to the supporting fabric to "coat" the skin external preparation, and coated with an adhesive layer so that the patch can be firmly adhered to the target site. on.

然而,不論習知溼式敷材浸泡皮膚外用劑(如玻尿酸、膠原蛋白等)或是乾式敷材塗佈皮膚外用劑,液體或凝膠狀的皮膚外用劑在敷材上的分布有無法達成期望濃度之問題。詳言之,溼式敷材係直接以皮膚外用劑浸潤,因此敷材整體會具有均勻濃度之皮膚外用劑,當將其貼附於皮膚使用時,僅有表面的皮膚外用劑可被肌膚吸收,進而造成敷材(例如不織布)內部吸附的皮膚外用劑因無法被吸收而被浪費掉。另一方面,乾式敷材係將皮膚外用劑塗佈於敷材表面,理論上塗佈當下其表面濃度會最高,然實際上皮膚外用劑卻會隨著存放時間越長而逐漸滲透進敷材內部,使得最終整體濃度仍是均勻分布於整個敷材,如此一來,敷材表面之皮膚外用劑的濃度必然會下降,與原先塗佈後的外用劑期望濃度有落差,無法維持初始塗佈後的濃度之設定,且易造成皮膚外用劑的浪費。再者,後續在使用乾式敷材時,由於無法使肌膚與期望濃度的皮膚外用劑接觸進而吸收,而造成皮膚外用劑的功效不彰之問題。However, regardless of the conventional wet dressing soaking skin external preparations (such as hyaluronic acid, collagen, etc.) or dry application materials for skin external preparation, the distribution of liquid or gel-like skin external preparation on the dressing material cannot be achieved. The problem of expected concentration. In detail, the wet dressing is directly infiltrated with the external preparation for skin, so that the whole material of the dressing material has a uniform concentration of the skin external preparation, and when applied to the skin, only the external skin preparation for the skin can be absorbed by the skin. Further, the skin external preparation adsorbed inside the dressing (for example, non-woven fabric) is wasted because it cannot be absorbed. On the other hand, the dry application material applies the external preparation for skin to the surface of the application material, and theoretically, the surface concentration of the application is the highest, but in fact, the external preparation for skin gradually penetrates into the application material as the storage time is longer. Internally, the final overall concentration is evenly distributed throughout the dressing. As a result, the concentration of the skin external preparation on the surface of the dressing is inevitably lowered, which is inferior to the desired concentration of the externally applied agent, and the initial coating cannot be maintained. After the concentration is set, and it is easy to cause waste of external preparation for skin. Further, in the subsequent use of the dry dressing, since the skin cannot be absorbed by contact with the skin external preparation of a desired concentration, the effect of the external preparation for the skin is not problematic.

此外,一般而言,當使用敷材時,可透過敷材與貼附肌膚部位之間的封閉空間的溫度上升,來達成局部肌膚吸收皮膚外用劑之功效。以溼式敷材例如面膜作為說明,當使用者將面膜敷在臉部時,理論上肌膚可因敷上面膜而與外部空氣隔離,使肌膚與面膜之間形成一封閉空間,當此空間被體溫微微加熱時,肌膚表面溫度會升高(大約僅上升1℃),毛細孔因熱溫而打開且微血管擴張,此時面膜上的皮膚外用劑可透過經皮吸收進入肌膚皮層,增加肌膚對該皮膚外用劑的吸收。在習知的醫學領域中,溼式敷材面膜之經皮吸收原理亦可應用於皮膚病患者,例如針對乾癬或慢性溼疹皮膚病患者的封閉式療法,由於其病灶的角質層太厚,故而在患部擦藥之後,再將患部包以保鮮膜或是防水不透氣之塑料用以使局部肌膚之溫度上升,如此可增加患部肌膚對藥物的吸收速率。Further, in general, when a dressing material is used, the temperature of the enclosed space between the dressing material and the skin portion can be increased to achieve the effect of the local skin absorbing the external preparation for the skin. As a description of the wet dressing such as the mask, when the user applies the mask to the face, the skin can theoretically be separated from the outside air by the application of the film, so that a space is formed between the skin and the mask, when the space is When the body temperature is slightly heated, the surface temperature of the skin will increase (about 1 °C only), the capillary pores open due to the heat temperature and the microvasculature expands. At this time, the skin external preparation on the mask can be absorbed into the skin cortex through the percutaneous absorption, increasing the skin pair. The absorption of the external preparation for skin. In the conventional medical field, the principle of percutaneous absorption of a wet dressing mask can also be applied to patients with dermatological diseases, such as closed therapy for patients with dry or chronic eczema skin diseases, because the stratum corneum of the lesion is too thick, Therefore, after rubbing the affected part, the affected part is covered with plastic wrap or waterproof and airtight plastic to increase the temperature of the local skin, thus increasing the absorption rate of the affected part of the skin.

然而,溼式敷材面膜有仍需改善之處。溼式敷材面膜僅使用單層布料浸潤皮膚外用劑,然在使用過程中,面膜與肌膚之間的形成的微空間中的熱氣易受外在環境溫度干擾,不易維持所欲的溫度。如此一來,溼式敷材面膜並無法使皮膚外用劑有效被肌膚所吸。此外,皮膚外用劑(大多為液體或凝膠狀)由於比熱關係在較低氣溫(如冬天)之環境下較為冰冷,增加使用上的不適。However, there is still room for improvement in wet-laid masks. The wet-laid mask uses only a single layer of cloth to infiltrate the skin external preparation. However, during use, the hot air in the micro-space formed between the mask and the skin is easily disturbed by the external environment temperature, and it is difficult to maintain the desired temperature. As a result, the wet dressing mask does not allow the skin external preparation to be effectively absorbed by the skin. In addition, skin external preparations (mostly liquid or gel-like) are relatively cold due to the specific heat relationship in a low temperature (such as winter) environment, which increases the discomfort in use.

另一方面,習知乾式敷材亦有待改善之處。以痠痛貼布舉例說明,習知痠痛貼布在貼附於使用者的肌膚部位時,係透過肌膚及貼布之間緊密的微環境,使止痛消炎之特定成分能對患部產生溫熱感。但該些溫熱感將隨著消炎止痛化學成分揮發或經皮吸收而逐漸消失,無法持續發熱一段特定的時間。On the other hand, there is still room for improvement in conventional dry dressings. Taking a sore patch as an example, a conventional sore patch adheres to the skin of the user and penetrates the tight micro-environment between the skin and the patch, so that the specific component of the pain relief and inflammation can produce a warm feeling to the affected part. However, these warm feelings will gradually disappear with the oxidation or percutaneous absorption of the anti-inflammatory and analgesic chemical components, and the heat cannot be sustained for a certain period of time.

雖然目前已有發熱型熱敷眼罩,然該熱敷眼罩係僅具有簡單的發熱結構,純粹僅能提供熱敷效果。Although there is a heat-generating thermal eye mask at present, the heat-applied eye mask has only a simple heat-generating structure, and can only provide a heat-applying effect.

在改善敷材結構以俾達到最佳發熱經皮吸收效果的技術上,有先前技術如中華民國新型專利TW M489550揭露之護膚加熱裝置,其利用熱敷包與護膚膜單元分別放置於具有隔室的袋體中,在使用護膚膜單元之前可先行藉由該熱敷包加熱護膚膜單元。然而由於熱敷包僅能在使用前加熱護膚膜單元,當護膚膜單元從袋體移出後,將容易散失熱度,如此無法於使用護膚膜單元之同時達到持續熱敷效果,熱敷效果不佳。In the technique of improving the structure of the dressing material to achieve the best heat transdermal absorption effect, there is a skin care heating device disclosed in the prior art, such as the Republic of China new patent TW M489550, which is separately placed in a compartment with a heat pack and a skin care film unit. In the bag body, the skin care film unit can be heated by the heat pack before using the skin care film unit. However, since the heat pack can only heat the skin care film unit before use, when the skin care film unit is removed from the bag body, it will easily lose heat, so that the skin heat treatment unit can not be used while achieving the continuous heat application effect, and the heat application effect is not good.

因此,為了改善前述缺失,本創作之目的在於提供一種可將皮膚外用劑集中於半固體凝膠層之表面,並可於敷上肌膚的同時進行熱敷的發熱敷材結構。為了達成前述目的,本創作提供一種發熱敷材結構,其包含結合具有濃度梯度的皮膚外用劑之半固體凝膠層,在敷於肌膚之同時,透過穩定的發熱體,提高溫度以促進該皮膚外用劑之經皮吸收效率。Therefore, in order to improve the aforementioned deficiency, the object of the present invention is to provide a heat-cured material structure in which a skin external preparation is concentrated on the surface of a semi-solid gel layer and can be applied while being applied to the skin. In order to achieve the above object, the present invention provides a heat-cured material structure comprising a semi-solid gel layer combined with a skin external preparation having a concentration gradient, which is applied to the skin while raising a temperature to promote the skin through a stable heat generating body. Transdermal absorption efficiency of the external preparation.

本創作提供一種發熱敷材結構,其包含薄型發熱體,其厚度為小於5 mm;以及半固體凝膠層,其包含第一面及第二面,半固體凝膠層之第一面與薄型發熱體貼合。其中,半固體凝膠層包含皮膚外用劑,皮膚外用劑於半固體凝膠層之第二面具有第一濃度,於半固體凝膠層之第一面有第二濃度,且第一濃度大於第二濃度。The present invention provides a heat-producing structure comprising a thin heating element having a thickness of less than 5 mm; and a semi-solid gel layer comprising a first side and a second side, the first side and the thin side of the semi-solid gel layer The heating element fits. Wherein the semi-solid gel layer comprises a skin external preparation, the skin external preparation has a first concentration on the second side of the semi-solid gel layer, the second concentration on the first side of the semi-solid gel layer, and the first concentration is greater than The second concentration.

較佳地,本創作可進一步包含於半固體凝膠層的第一面及第二面之間具有第三濃度的皮膚外用劑。Preferably, the present invention may further comprise a third concentration of the skin external preparation between the first side and the second side of the semi-solid gel layer.

較佳地,第一濃度可大於第三濃度,第三濃度可大於第二濃度。Preferably, the first concentration may be greater than the third concentration, and the third concentration may be greater than the second concentration.

較佳地,第一濃度與第二濃度之差值可至少大於20%。Preferably, the difference between the first concentration and the second concentration may be at least greater than 20%.

較佳地,半固體凝膠層可包含固形物及水。Preferably, the semi-solid gel layer may comprise solids and water.

承上述,固形物可包含選自聚丙烯酸系、多元醇系、聚乙烯醇系、聚乙烯基吡咯烷酮、其共聚物、其組合物及其組合的群組的親水性高分子材料,其中親水性高分子材料之分子量可大於1×10 5In the above, the solid matter may comprise a hydrophilic polymer material selected from the group consisting of polyacrylic acid, polyhydric alcohol, polyvinyl alcohol, polyvinyl pyrrolidone, copolymers thereof, combinations thereof, and combinations thereof, wherein hydrophilicity The molecular weight of the polymer material can be greater than 1 × 10 5 .

較佳地,固形物占半固體凝膠層之總重量百分比可為1%至70%。Preferably, the solids may comprise from 1% to 70% by weight of the total weight of the semi-solid gel layer.

較佳地,半固體凝膠層之含水率可為30%至99%。Preferably, the semi-solid gel layer may have a water content of from 30% to 99%.

較佳地,本創作進一步可包含設置於半固體凝膠層與薄型發熱體之間之第一支撐層,以及設置於第一支撐層與薄型發熱體之間之第一黏合層。Preferably, the present invention further includes a first support layer disposed between the semi-solid gel layer and the thin heating element, and a first adhesive layer disposed between the first support layer and the thin heating element.

較佳地,本創作進一步可包含設置於薄型發熱體面對第一黏合層之相對面之第二支撐層;以及設置於第二支撐層與薄型發熱體之間之第二黏合層。Preferably, the present invention further includes a second supporting layer disposed on the opposite side of the thin heating element facing the first bonding layer; and a second bonding layer disposed between the second supporting layer and the thin heating element.

較佳地,薄型發熱體之發熱溫度為28℃至45℃。Preferably, the heat generating temperature of the thin heating element is from 28 ° C to 45 ° C.

承上所述,本創作提供一種發熱敷材結構,其結合薄型發熱體與半固體凝膠層,具有以下多個優點:As described above, the present invention provides a heat-producing structure which combines a thin heating element and a semi-solid gel layer, and has the following advantages:

(1) 本創作之發熱敷材結構,其半固體凝膠層包含高分子親水性材料之固形物,可使塗佈的皮膚外用劑集中於半固體凝膠層之表面,使該表面具有最高濃度之皮膚外用劑。(1) The heat-cured material structure of the present invention, the semi-solid gel layer comprising a solid material of a polymer hydrophilic material, which can concentrate the applied skin external preparation on the surface of the semi-solid gel layer, so that the surface has the highest A skin external preparation for concentration.

(2) 本創作之發熱敷材結構,薄型發熱體可於固定時間內穩定發熱,提高肌膚與敷材之間的封閉空間的溫度,達到熱敷效應,進而可舒緩傷病部位、促進血液循環並增加局部之經皮吸收率。(2) The heat-producing structure of the creation, the thin heating element can stably heat up within a fixed time, improve the temperature of the enclosed space between the skin and the dressing, and achieve the hot compress effect, thereby relaxing the wounded part, promoting blood circulation and increasing Local percutaneous absorption rate.

(3)本創作之發熱敷材結構,皮膚外用劑以最高濃度維持集中於半固體凝膠層之表面,可利於使用者有效吸收該皮膚外用劑。此外,透過薄型發熱體加熱,達到緩釋效應,可延長皮膚外用劑之釋放時間,可促使滲透進半固體凝膠層內部之較低的皮膚外用劑繼而可被肌膚吸收。(3) The structure of the heat-applied material of the present invention, the skin external preparation is maintained at the highest concentration to concentrate on the surface of the semi-solid gel layer, which is beneficial for the user to effectively absorb the external preparation for the skin. In addition, the thin-type heating element is heated to achieve a sustained release effect, which can prolong the release time of the external preparation for the skin, and promote the lower skin external preparation which penetrates into the semi-solid gel layer to be absorbed by the skin.

本創作提供一實施例,其為一種發熱敷材結構。本實施例之發熱敷材結構可參考圖式第1圖來理解。第1圖係為根據本創作之一實施例的發熱敷材結構示意圖。該發熱敷材結構10包含薄型發熱體110以及半固體凝膠層120。薄型發熱體110之厚度可為0.1至5 mm,半固體凝膠層120之厚度可為0.1 mm至3 mm。薄型發熱體110係與半固體凝膠層120之一面貼合,其中半固體凝膠層120塗佈有一皮膚外用劑125,該皮膚外用劑125具有第一濃度及第二濃度。其中,在半固體凝膠層120不與薄型發熱體110貼合之另一面塗佈之皮膚外用劑125具有第一濃度,半固體凝膠層120與薄型發熱體110貼合之該面塗佈之皮膚外用劑125具有第二濃度,且第一濃度大於第二濃度。This creation provides an embodiment which is a heat-fed construction. The structure of the heat-generating material of this embodiment can be understood by referring to Fig. 1 of the drawings. Fig. 1 is a schematic view showing the structure of a heat-generating material according to an embodiment of the present invention. The heat-generating material structure 10 includes a thin heat generating body 110 and a semi-solid gel layer 120. The thin heating element 110 may have a thickness of 0.1 to 5 mm, and the semi-solid gel layer 120 may have a thickness of 0.1 mm to 3 mm. The thin heating element 110 is bonded to one side of the semi-solid gel layer 120, wherein the semi-solid gel layer 120 is coated with a skin external preparation 125 having a first concentration and a second concentration. The skin external preparation 125 coated on the other side of the semi-solid gel layer 120 that is not bonded to the thin heating element 110 has a first concentration, and the semi-solid gel layer 120 is coated with the thin heating element 110. The skin external preparation 125 has a second concentration, and the first concentration is greater than the second concentration.

更進一步地,皮膚外用劑125可包含第三濃度。亦即,在半固體凝膠層120內部的皮膚外用劑125係塗佈有第三濃度,且第一濃度大於第三濃度,第三濃度大於第二濃度,且第一濃度與第二濃度之差值至少為20%。Further, the skin external preparation 125 may contain a third concentration. That is, the skin external preparation 125 inside the semi-solid gel layer 120 is coated with a third concentration, and the first concentration is greater than the third concentration, the third concentration is greater than the second concentration, and the first concentration and the second concentration are The difference is at least 20%.

本創作之實施例的薄型發熱體110主要以鐵粉、鹽、活性碳、保水劑、蛭石與水之發熱成分組成。此外,薄型發熱體110包含一包裝材,該包裝材可為不織布。前述發熱成分係封裝於包裝材內,並形成厚度小於5 mm之薄型發熱體110。詳言之,薄型發熱體110厚度可控制在0.1 mm至5 mm之內,較佳地可為0.1 mm至3 mm。在使用時,薄型發熱體110之發熱溫度為28℃至45℃,較佳者為與人體肌膚相似的溫度,如35℃至45℃。The thin heating element 110 of the embodiment of the present invention is mainly composed of iron powder, salt, activated carbon, water retaining agent, vermiculite and water. Further, the thin heating element 110 includes a packaging material, which may be a non-woven fabric. The heat generating component is encapsulated in a packaging material to form a thin heat generating body 110 having a thickness of less than 5 mm. In detail, the thickness of the thin heating element 110 can be controlled within 0.1 mm to 5 mm, preferably 0.1 mm to 3 mm. In use, the heat generating temperature of the thin heating element 110 is from 28 ° C to 45 ° C, preferably a temperature similar to that of human skin, such as 35 ° C to 45 ° C.

本創作之實施例的半固體凝膠層120包含固形物及水。固形物係選自由聚丙烯酸系、多元醇系、聚乙烯醇系(PVA)、聚乙烯基吡咯烷酮(PVP)、其組合物、其共聚物或其組合(例如聚苯乙酸丙烯酸共聚物)的群組的親水性高分子材料。且該些親水性高分子材料之分子量大於1×10 5。半固體凝膠層之固形物占半固體凝膠層總重量百分比可為1%至70%,較佳為3%至30%。半固體凝膠層之厚度可為0.1 mm至3 mm。當半固體凝膠層120係以親水性高分子材料形成時,半固體凝膠層120可含有相當高的含水率,舉例來說,半固體凝膠層120之含水率可為30%至99%,較佳的含水率為50%至95%。半固體凝膠層120塗佈皮膚外用劑125,皮膚外用劑125占總半固體凝膠層之重量比例可為1%至5%。 The semi-solid gel layer 120 of the presently described embodiment contains solids and water. The solid matter is selected from the group consisting of polyacrylic acid, polyol, polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), combinations thereof, copolymers thereof, or combinations thereof (for example, polyphenylacetic acid acrylic copolymer). Group of hydrophilic polymer materials. And the molecular weight of the hydrophilic polymer materials is greater than 1×10 5 . The solids of the semi-solid gel layer may range from 1% to 70%, preferably from 3% to 30%, by total weight of the semi-solid gel layer. The semi-solid gel layer may have a thickness of 0.1 mm to 3 mm. When the semi-solid gel layer 120 is formed of a hydrophilic polymer material, the semi-solid gel layer 120 may contain a relatively high water content. For example, the semi-solid gel layer 120 may have a water content of 30% to 99. %, preferably a water content of 50% to 95%. The semi-solid gel layer 120 is coated with the skin external preparation 125, and the skin external preparation 125 may be in a ratio of 1% to 5% by weight based on the total semi-solid gel layer.

詳言之,本創作之半固體凝膠層120係由親水性高分子材料之固形物及水組成。當皮膚外用劑125被塗佈於半固體凝膠層120之表面時,皮膚外用劑125的化學分子會受到分子間正負電荷作用力的吸引而被集中在半固體凝膠層120的親水性高分子聚合物裡。如此皮膚外用劑125的濃度可在接近半固體凝膠層120之表層時具有最高濃度,而僅有少部分的皮膚外用劑125擴散至半固體凝膠層120之深處,故形成濃度梯度之現象。In detail, the semi-solid gel layer 120 of the present invention is composed of a solid material of a hydrophilic polymer material and water. When the skin external preparation 125 is applied to the surface of the semi-solid gel layer 120, the chemical molecules of the skin external preparation 125 are attracted by the intermolecular positive and negative charges, and the hydrophilicity of the semi-solid gel layer 120 is concentrated. In the molecular polymer. Thus, the concentration of the external preparation for skin 125 can be the highest concentration near the surface layer of the semi-solid gel layer 120, and only a small portion of the external preparation for skin 125 diffuses to the depth of the semi-solid gel layer 120, so that a concentration gradient is formed. phenomenon.

根據前述本創作之半固體凝膠層120的設置,本創作提供之發熱敷材結構上塗佈之皮膚外用劑125可呈現濃度梯度。詳細來說,該皮膚外用劑125的濃度可分為三至六個濃度區間。According to the above-described arrangement of the semi-solid gel layer 120 of the present invention, the skin external preparation 125 coated on the heat-applied structure of the present invention can exhibit a concentration gradient. In detail, the concentration of the external preparation for skin 125 can be divided into three to six concentration intervals.

以下以三個濃度區間作為說明。本創作的實施例中描述的第一區間,係指半固體凝膠層120不與薄型發熱體110貼合之一面(亦即表面);第二區間則指半固體凝膠層120從表面向與薄型發熱體110貼合之一面的方向(向下)延伸之50%的深度;第三區間則為半固體凝膠層120從50%的深度至100%深度之區間。皮膚外用劑125的濃度在第一區間、第二區間以及第三區間內分別具有不同的濃度。皮膚外用劑125於第一區間的濃度為是最接近初始塗佈的濃度,因而第一區間的濃度最高。在此將皮膚外用劑125於第一區間的濃度定義為100%,則皮膚外用劑125於第二區間的濃度則為40至100%;皮膚外用劑125在第三區間內的濃度係小於40%。簡言之,皮膚外用劑125之濃度於半固體凝膠層120之表面的濃度最高,皮膚外用劑係以低濃度存在於半固體凝膠層120之深度50%以下之處,且皮膚外用劑於第一區間的濃度與第三區間的濃度的差值可為大於60%。The following three concentration intervals are used as an explanation. The first section described in the embodiment of the present invention means that the semi-solid gel layer 120 does not adhere to one side (ie, the surface) of the thin heating element 110; the second section refers to the semi-solid gel layer 120 from the surface to the surface. A depth of 50% of the direction in which one side of the thin heating element 110 is attached (downward); the third section is a section from the depth of 50% to a depth of 100% of the semi-solid gel layer 120. The concentration of the external preparation for skin 125 has different concentrations in the first section, the second section, and the third section, respectively. The concentration of the skin external preparation 125 in the first section is the concentration closest to the initial coating, and thus the concentration in the first section is the highest. Here, the concentration of the skin external preparation 125 in the first section is defined as 100%, and the concentration of the skin external preparation 125 in the second section is 40 to 100%; and the concentration of the external preparation 125 of the skin in the third interval is less than 40. %. In short, the concentration of the external preparation for skin 125 is the highest on the surface of the semi-solid gel layer 120, and the external preparation for skin is present at a low concentration of 50% or less of the depth of the semi-solid gel layer 120, and the external preparation for skin The difference between the concentration in the first interval and the concentration in the third interval may be greater than 60%.

相似地,根據本創作一實施例的發熱敷材結構,亦呈現另一皮膚外用劑125的濃度梯度之分布。在此分布中,皮膚外用劑125的濃度分成六個濃度區間,並請參閱第2圖,其為半固體凝膠層之深度與皮膚外用劑濃度之分布關係圖。在此定義半固體凝膠層120之表面為第一區間,該區間之皮膚外用劑125的濃度係最接近初始塗佈的濃度,以濃度的100%計;第二區間係半固體凝膠層120從表面向半固體凝膠層125相對於表面延伸10%之深度,該區間內的皮膚外用劑125之濃度為≥90%且<100%;第三區間係半固體凝膠層120從深度10%至深度35%之處,該區間之皮膚外用劑125之濃度為70%至90%;第四區間係為半固體凝膠層120從30%至50%之深度,該區間具有皮膚外用劑125的35%至70%的濃度5;第五區間係指半固體凝膠層120從50至80%的深度,該區間包含10%至35%濃度之皮膚外用劑125;第六區間係指半固體凝膠層120從80%深度以下之處,該區間包含少於10%濃度之皮膚外用劑125。從第2圖可看出,皮膚外用劑125之濃度於半固體凝膠層120之表面的濃度最高,而皮膚外用劑以低濃度存在於半固體凝膠層120深度為80%至100%之處,且皮膚外用劑的最高濃度與最低濃度的差值可大於90%。Similarly, according to the heat-generating dressing structure of one embodiment of the present creation, the distribution of the concentration gradient of the other skin external preparation 125 is also exhibited. In this distribution, the concentration of the external preparation for skin 125 is divided into six concentration intervals, and reference is made to Fig. 2, which is a graph showing the relationship between the depth of the semi-solid gel layer and the concentration of the external preparation for skin. Here, the surface of the semi-solid gel layer 120 is defined as a first interval, and the concentration of the skin external agent 125 in the interval is closest to the initial coating concentration, which is 100% of the concentration; the second interval is a semi-solid gel layer. 120 extends from the surface to the semi-solid gel layer 125 by a depth of 10% with respect to the surface, the concentration of the skin external preparation 125 in the interval is ≥90% and <100%; the third interval is the semi-solid gel layer 120 from the depth From 10% to 35% of the depth, the concentration of the skin external preparation 125 in the interval is 70% to 90%; the fourth interval is the depth of the semi-solid gel layer 120 from 30% to 50%, and the interval has skin external application. The concentration of the agent 125 is 35% to 70%; the fifth interval means the depth of the semi-solid gel layer 120 from 50 to 80%, and the interval includes the skin external preparation 125 of 10% to 35%; the sixth interval is Refers to the semi-solid gel layer 120 from below 80% depth, which contains less than 10% concentration of the skin external preparation 125. As can be seen from Fig. 2, the concentration of the external preparation for skin 125 is the highest on the surface of the semi-solid gel layer 120, and the external preparation for skin is present at a low concentration of the semi-solid gel layer 120 at a depth of 80% to 100%. The difference between the highest concentration and the lowest concentration of the external preparation for skin may be greater than 90%.

皮膚外用劑之實例可為保溼劑、美白劑、經皮吸收藥物等,然不限於此。Examples of the external preparation for skin may be a moisturizer, a whitening agent, a percutaneous absorption medicine, etc., but are not limited thereto.

本創作亦提供另一實施例,其為一種發熱敷材結構。本實施例可參考圖式第3圖來理解。第3圖係為根據本創作之另一實施例的發熱敷材結構示意圖。發熱敷材結構20包含薄型發熱體210及半固體凝膠層220,且進一步包含設置於半固體凝膠層220與薄型發熱體210之間的第一支撐層230,係用於支撐半固體凝膠層220;以及設置於薄型發熱體210與第一支撐層230之間的第一黏合層240,係用於將薄型發熱體210與第一支撐層230黏合固定。第一支撐層230之厚度可為0.1至2 mm,較佳為0.1 mm至0.5 mm;第一黏合層之厚度可為0.01 mm至3 mm,較佳者為0.02 mm至0.5 mm。This creation also provides another embodiment which is a heat resistant scaffolding structure. This embodiment can be understood by referring to FIG. 3 of the drawing. Fig. 3 is a schematic view showing the structure of a heat-generating material according to another embodiment of the present invention. The heating material structure 20 includes a thin heating element 210 and a semi-solid gel layer 220, and further includes a first supporting layer 230 disposed between the semi-solid gel layer 220 and the thin heating element 210 for supporting semi-solid condensation The adhesive layer 220 and the first adhesive layer 240 disposed between the thin heat generating body 210 and the first supporting layer 230 are used for bonding and fixing the thin heating element 210 and the first supporting layer 230. The first support layer 230 may have a thickness of 0.1 to 2 mm, preferably 0.1 mm to 0.5 mm; the first adhesive layer may have a thickness of 0.01 mm to 3 mm, preferably 0.02 mm to 0.5 mm.

本創作之另一實施例之發熱敷材結構20所包含的薄型發熱體210及半固體凝膠層220與前述一實施例的薄型發熱體110及半固體凝膠層120具有相似之材料及結構,請參閱前述說明於此不在贅述。其中,半固體凝膠層220包含一皮膚外用劑225。與前述實施例相同,半固體凝膠層220包含的皮膚外用劑225可集中於半固體凝膠層220之表面,使皮膚外用劑225在半固體凝膠層220之表面具有最高濃度,而越往半固體凝膠層220之深處,皮膚外用劑225之濃度越低。The thin heating element 210 and the semi-solid gel layer 220 included in the heat-generating material structure 20 of another embodiment of the present invention have similar materials and structures as the thin-type heating element 110 and the semi-solid gel layer 120 of the foregoing embodiment. Please refer to the above description for details. Among them, the semi-solid gel layer 220 contains a skin external preparation 225. As in the foregoing embodiment, the semi-solid gel layer 220 contains the skin external preparation 225 which can concentrate on the surface of the semi-solid gel layer 220, so that the skin external preparation 225 has the highest concentration on the surface of the semi-solid gel layer 220, and the more To the depth of the semi-solid gel layer 220, the concentration of the skin external preparation 225 is lower.

本創作之另一實施例中,第一支撐層230用於支撐整體發熱敷材結構20,且第一支撐層230為化學纖維材料或天然纖維材料。化學纖維材料包含但不限於不織布、聚酯、尼龍等;天然纖維材料包含但不限於木漿、棉、麻、蠶絲、生物纖維等。第一黏合層240主要用於將薄型發熱體210之一面與第一支撐層230之一面結合。第一黏合層240可包含化學纖維層(例如聚四氟乙烯材料所形成之防水透氣膜之夾層)、聚氨酯、丙烯酸類等黏著劑、或其組合。In another embodiment of the present invention, the first support layer 230 is used to support the integral heat-generating sheath structure 20, and the first support layer 230 is a chemical fiber material or a natural fiber material. Chemical fiber materials include, but are not limited to, non-woven fabrics, polyesters, nylons, and the like; natural fiber materials include, but are not limited to, wood pulp, cotton, hemp, silk, bio-fibers, and the like. The first adhesive layer 240 is mainly used to bond one surface of the thin heating element 210 to one surface of the first support layer 230. The first adhesive layer 240 may include a chemical fiber layer (for example, an interlayer of a waterproof gas permeable film formed of a polytetrafluoroethylene material), an adhesive such as polyurethane or acrylic, or a combination thereof.

根據本創作之實施例,於此提供例示性實施方式如下。本創作所屬技術領域具有通常知識者,可參酌圖式而更簡易良好地理解本創作的技術內容。According to an embodiment of the present creation, an exemplary embodiment is provided herein as follows. The technical field of the present invention belongs to those skilled in the art, and the technical content of the present creation can be understood more easily and easily by referring to the schema.

本創作提供第一實施方式,其為利用本創作之實施例之發熱敷材結構製成一乾敷型面膜之實施方式。The present invention provides a first embodiment which is an embodiment in which a dry-laid mask is formed using the heat-applied material structure of the embodiment of the present invention.

請參閱第4圖,係為本創作之第一實施方式的乾敷型面膜之示意圖。第一實施方式提供一種乾敷型面膜30,其從面膜最外側之面至與臉部接觸之面之結構依序為薄型發熱體310、第一黏合層320、第一支撐層330、半固體凝膠層340。Please refer to FIG. 4, which is a schematic view of the dry-faced mask of the first embodiment of the present invention. The first embodiment provides a dry-type mask 30, which is a thin heat generating body 310, a first adhesive layer 320, a first supporting layer 330, and a semi-solid from the outermost surface of the mask to the surface in contact with the face. Gel layer 340.

在此實施方式中,薄型發熱體310主要包含鐵粉、鹽、活性碳、保水劑、蛭石與水組成之發熱成分。該些成分之比例為鐵粉:鹽:活性碳:保水劑:蛭石:水=6:1.2:1:1:1:3。然該比例僅為舉例說明,可不限於此。此外,薄型發熱體310包含一包裝材,該包裝材可為不織布。前述發熱成分透過所屬領域具有通常知識者習知之技藝封裝於包裝材內。在本次實施方式中,薄型發熱體310之厚度為0.26 mm。In this embodiment, the thin heat generating body 310 mainly contains a heat generating component composed of iron powder, salt, activated carbon, water retaining agent, vermiculite and water. The proportion of these ingredients is iron powder: salt: activated carbon: water retention agent: vermiculite: water = 6: 1.2:1:1:1:3. However, the ratio is merely illustrative and may not be limited thereto. Further, the thin heating element 310 includes a packaging material, which may be a non-woven fabric. The aforementioned heat generating component is encapsulated in a packaging material by a technique known to those skilled in the art. In the present embodiment, the thickness of the thin heating element 310 is 0.26 mm.

進一步,第一黏合層320主要用於將薄型發熱體310之一面與第一支撐層330之一面結合。如前述本創作之一實施例所述,第一黏合層320可包含化學纖維層(例如聚四氟乙烯材料所形成之防水透氣膜之夾層)、聚氨酯、丙烯酸類等黏著劑、或其組合。在本實施方式中,第一黏合層320包含化學纖維層及聚氨酯(PUR)黏著劑。化學纖維層設置於薄型發熱體310一面,並透過聚氨酯黏著劑將薄型發熱體310與該化學纖維層黏合固定。在本次實施方式中,第一黏合層320之厚度為0.03 mm。Further, the first adhesive layer 320 is mainly used to bond one surface of the thin heating element 310 to one surface of the first support layer 330. As described in one embodiment of the present invention, the first adhesive layer 320 may include a chemical fiber layer (for example, an interlayer of a waterproof gas-permeable film formed of a polytetrafluoroethylene material), an adhesive such as polyurethane or acrylic, or a combination thereof. In the present embodiment, the first adhesive layer 320 comprises a chemical fiber layer and a polyurethane (PUR) adhesive. The chemical fiber layer is provided on one side of the thin heating element 310, and the thin heating element 310 is bonded and fixed to the chemical fiber layer through a urethane adhesive. In this embodiment, the thickness of the first adhesive layer 320 is 0.03 mm.

在此實施方式中,第一支撐層330用於支撐整體乾敷型面膜,且第一支撐層為化學纖維材料或天然纖維材料。如前所述,化學纖維材料包含但不限於不織布、聚酯、尼龍等;天然纖維材料包含但不限於木漿、棉、麻、蠶絲、生物纖維等。在此實施方式的乾敷型面膜中,第一支撐層330為不織布材料,且第一支撐層330之厚度為0.1 mm。第一支撐層330作為主體結構,主要用來維持乾敷型面膜30之形狀及穩定性。In this embodiment, the first support layer 330 is used to support the overall dry-laid mask, and the first support layer is a chemical fiber material or a natural fiber material. As mentioned above, chemical fiber materials include, but are not limited to, non-woven fabrics, polyesters, nylons, and the like; natural fiber materials include, but are not limited to, wood pulp, cotton, hemp, silk, bio-fibers, and the like. In the dry-type mask of this embodiment, the first support layer 330 is a non-woven material, and the first support layer 330 has a thickness of 0.1 mm. The first support layer 330 serves as a main structure and is mainly used to maintain the shape and stability of the dry-laid mask 30.

進一步,半固體凝膠層340包含固形物及水,根據本創作之實施例,固形物係由親水性高分子複合材料形成,其可為聚丙烯酸系、多元醇系、聚乙烯醇系(PVA)、聚乙烯基吡咯烷酮(PVP)、其組合物、其共聚物或其組合(例如聚苯乙酸丙烯酸共聚物),且該些親水性高分子材料之分子量大於1×10 5。在此實施方式中,半固體凝膠層340之厚度為2 mm。 Further, the semi-solid gel layer 340 comprises a solid material and water. According to an embodiment of the present invention, the solid material is formed of a hydrophilic polymer composite material, which may be a polyacrylic acid type, a polyhydric alcohol type, or a polyvinyl alcohol type (PVA). And polyvinylpyrrolidone (PVP), a composition thereof, a copolymer thereof or a combination thereof (for example, a polyphenylacetic acid acrylic copolymer), and the hydrophilic polymer materials have a molecular weight of more than 1 × 10 5 . In this embodiment, the semi-solid gel layer 340 has a thickness of 2 mm.

此外,半固體凝膠層340之表面塗佈有皮膚外用劑325。當半固體凝膠層340內含有皮膚外用劑325時,該些皮膚外用劑325的有效成分,例如保養保溼美白等功效成分,可藉由化學分子間作用力滲入半固體凝膠層340中,而被鎖在高分子聚合物裡。此外,透過半固體凝膠層340之材料的正負電荷,以及該些聚合物之高分子量,使得皮膚外用劑325被塗佈於半固體凝膠層340上時,可被集中在半固體凝膠層340之表層,而使得半固體凝膠層340之表面之皮膚外用劑325的濃度接近最初塗佈的初始皮膚外用劑325之濃度,僅有少部分的皮膚外用劑325逐漸往半固體凝膠層340之底層遞減,形成濃度梯度之現象。在此乾敷型面膜30之實施方式中,皮膚外用劑主要為保溼成分。Further, the surface of the semi-solid gel layer 340 is coated with a skin external preparation 325. When the skin external preparation 325 is contained in the semi-solid gel layer 340, the active ingredients of the skin external preparation 325, for example, moisturizing whitening and the like, can be infiltrated into the semi-solid gel layer 340 by chemical intermolecular force. And is locked in the polymer. In addition, the positive and negative charges of the material passing through the semi-solid gel layer 340, and the high molecular weight of the polymers, allow the skin external preparation 325 to be concentrated on the semi-solid gel layer when applied to the semi-solid gel layer 340. The surface layer 340 is such that the concentration of the skin external preparation 325 on the surface of the semi-solid gel layer 340 is close to the concentration of the initially applied initial skin external preparation 325, and only a small portion of the skin external preparation 325 gradually goes to the semi-solid gel. The bottom layer of layer 340 is decremented to form a concentration gradient. In the embodiment of the dry-type mask 30, the external preparation for skin is mainly a moisturizing ingredient.

在此實施方式中,半固體凝膠層之固形物包含下列材料:聚丙烯酸鈉(Sodium polyacrylate),分子量約為4×10 6,占半固體凝膠層之總重量百分比為1.5%;聚乙烯基吡咯烷酮,分子量3×10 6,占半固體凝膠層之總重量百分比為0.5%;吐溫(Tween) 80 (聚氧乙烯(20)-山梨醇酐單油酸酯),占半固體凝膠層之總重量百分比3%。皮膚保溼成分則包含玻尿酸 (分子量為1×10 5),占半固體凝膠層之總重量百分比1%;大分子玻尿酸(分子量為1×10 6),占半固體凝膠層之總重量百分比1%;甘油,占半固體凝膠層之總重量百分比0.5%;胺基酸類,占半固體凝膠層之總重量百分比1.5%;丙二醇,占半固體凝膠層之總重量百分比為1%。半固體凝膠層340之含水率為:90%。 In this embodiment, the solid matter of the semi-solid gel layer comprises the following material: sodium polyacrylate, having a molecular weight of about 4×10 6 , and accounting for 1.5% by weight of the semi-solid gel layer; Pyrrolidone, molecular weight 3 × 10 6 , accounting for 0.5% by weight of the semi-solid gel layer; Tween 80 (polyoxyethylene (20) - sorbitan monooleate), accounting for semi-solid condensation The total weight percentage of the rubber layer is 3%. The skin moisturizing ingredient contains hyaluronic acid (molecular weight 1×10 5 ), which accounts for 1% of the total weight of the semi-solid gel layer; macromolecular hyaluronic acid (molecular weight: 1×10 6 ), which accounts for the total weight of the semi-solid gel layer. Percentage 1%; glycerin, 0.5% by weight of the total weight of the semi-solid gel layer; amino acids, 1.5% by weight of the semi-solid gel layer; propylene glycol, based on the total weight of the semi-solid gel layer, 1 %. The water content of the semi-solid gel layer 340 was 90%.

實際以紅外線光譜分析儀測試本創作之保溼成分於乾敷型面膜30之半固體凝膠層340內部之濃度,可發現本創作的乾敷型面膜30之半固體凝膠層340包含五個保溼成分的濃度區間。若以半固體凝膠層340之表面(遠離薄型發熱體之面)的保溼成分為100%計,則半固體凝膠層340之深度為距離表面0.5 mm之處的保溼成分之濃度為64.5%;半固體凝膠層340深度為距離表面1 mm之處的保溼成分之濃度為62.2%;半固體凝膠層340深度為距離表面1.5 mm之處的保溼成分之濃度為48.9%;半固體凝膠層340深度為距離表面為2 mm之處的保溼成分之濃度為20.6%。Actually, the concentration of the moisturizing component of the present invention in the semi-solid gel layer 340 of the dry-type mask 30 was tested by an infrared spectrum analyzer, and it was found that the semi-solid gel layer 340 of the dry-laid mask 30 of the present invention contained five. The concentration range of the moisturizing ingredients. If the moisture content of the surface of the semi-solid gel layer 340 (away from the surface of the thin heating element) is 100%, the concentration of the semi-solid gel layer 340 at a depth of 0.5 mm from the surface is 64.5%; the concentration of the semi-solid gel layer 340 at a depth of 1 mm from the surface is 62.2%; the concentration of the semi-solid gel layer 340 at a depth of 1.5 mm from the surface is 48.9%. The concentration of the semi-solid gel layer 340 having a depth of 2 mm from the surface was 20.6%.

詳言之,在本實施方式中,由於聚乙烯基吡咯烷酮在水中解離成帶有正電荷的吡咯烷酮基團,而半固體凝膠層帶有負電荷丙烯酸官能基團。故而當作為皮膚外用劑的玻尿酸等保溼成分被塗佈至半固體凝膠層時,該些化學分子會被半固體凝膠層之表面的負電荷吸引,但又受到聚乙烯基吡咯烷酮聚合物分子的影響,玻尿酸等保溼成分被集中在半固體凝膠層之表層。如此一來,而半固體凝膠層之表面將維持最高濃度的保溼成分,僅有少部分的保溼成分滲入半固體凝膠層的較深處 (請參閱圖式第5圖),呈現如前述的濃度梯度之分布效應。In particular, in this embodiment, the polyvinylpyrrolidone dissociates into a positively charged pyrrolidone group in water, while the semi-solid gel layer carries a negatively charged acrylic functional group. Therefore, when a moisturizing component such as hyaluronic acid as a skin external preparation is applied to the semi-solid gel layer, the chemical molecules are attracted by the negative charge on the surface of the semi-solid gel layer, but are subjected to the polyvinylpyrrolidone polymer. Molecular effects, moisturizing ingredients such as hyaluronic acid are concentrated on the surface layer of the semi-solid gel layer. As a result, the surface of the semi-solid gel layer will maintain the highest concentration of moisturizing ingredients, and only a small portion of the moisturizing ingredients penetrate deep into the semi-solid gel layer (see Figure 5). The distribution effect of the concentration gradient as described above.

進一步地,當使用本創作第一實施方式的乾敷型面膜30時,將該面膜從包裝袋體取出並簡易搓揉,使薄型發熱體310開始釋放熱能並傳導至半固體凝膠層340。薄型發熱體310之發熱溫度為45℃,將半固體凝膠層340遠離薄型發熱體310之一面與臉部肌膚貼合,於此實際測量半固體凝膠層340表面之溫度為比人體體溫略高之溫度,大約在37至41℃。乾敷型面膜30除了可透過薄型發熱體310達成緩溫加熱至適合直接接觸肌膚使用的溫度之外,亦可維持該溫度一段特定時間,例如可維持大約45分鐘至1小時。Further, when the dry-type mask 30 of the first embodiment of the present invention is used, the mask is taken out from the package body and simply smashed, so that the thin heat generating body 310 starts to release heat energy and is conducted to the semi-solid gel layer 340. The heat generation temperature of the thin heating element 310 is 45 ° C, and the surface of the semi-solid gel layer 340 away from the surface of the thin heating element 310 is attached to the skin of the face, and the temperature of the surface of the semi-solid gel layer 340 is actually measured. High temperature, about 37 to 41 ° C. The dry-type mask 30 can maintain the temperature for a certain period of time, for example, for about 45 minutes to 1 hour, in addition to being able to be heated by the thin heating element 310 to a temperature suitable for direct contact with the skin.

當透過乾敷型面膜30的薄型發熱體310加熱半固體凝膠層340,整體面膜之溫度上升,使得與面膜接觸之肌膚溫度上升,如此肌膚毛細孔打開,增加經皮吸收之效率。此外,由於半固體凝膠層340內含的保溼成分係以濃度梯度分布於整體凝膠層中,且半固體凝膠層之表面的保溼成分為最高,如此亦增加使用者肌膚對保溼成分的吸收效率。為了進一步了解本創作之乾敷型面膜30之保溼功效,創作人將本創作之第一實施方式之乾敷型面膜貼附於受試者(三位)皮膚15分鐘,移除面膜後利用皮膚檢測儀測量肌膚的保溼度。敷用乾敷型面膜之後,三位受試者的皮膚保溼度之平均為57.3 %。進一步地,將本創作之乾敷型面膜之保溼效果與目前一般市售之習知溼敷面膜產品做功效測試之比較。取用四款市售的溼敷面膜產品,分別為得生製藥股份有限公司:水晶果凍面膜;森田藥妝:玻尿酸複合原液面膜;聖克萊爾:玻尿酸100%保溼面膜;以及LADY MARIAN美魔力:白珍珠潤白面膜。將該些面膜分別於不同天的相同時段,於肌膚上敷用15分鐘。使用市售面膜產品後的肌膚保溼度大約為37%至55%。與本創作之實施方式的乾敷型面膜相比,可發現使用本創作之第一實施方式的乾敷型面膜,可讓肌膚具有較高的保溼度(超過57%)。When the semi-solid gel layer 340 is heated by the thin heating element 310 of the dry-type mask 30, the temperature of the entire mask rises, so that the temperature of the skin in contact with the mask rises, so that the pores of the skin are opened, and the efficiency of percutaneous absorption is increased. In addition, since the moisturizing component contained in the semi-solid gel layer 340 is distributed in the entire gel layer with a concentration gradient, and the surface of the semi-solid gel layer has the highest moisturizing component, the user's skin is also protected. Absorption efficiency of wet components. In order to further understand the moisturizing effect of the dry-face mask 30 of the present invention, the creator attached the dry-face mask of the first embodiment of the present invention to the subject (three) skin for 15 minutes, and removed the mask and utilized it. The skin tester measures the moisturization of the skin. After application of the dry-face mask, the average skin moisturization of the three subjects was 57.3%. Further, the moisturizing effect of the dry-laid mask of the present invention is compared with the conventional commercially available wet-coated mask product. Take four commercially available wet-coated mask products, namely Desheng Pharmaceutical Co., Ltd.: Crystal Jelly Mask; Morita Cosmeceutical: Hyaluronic Acid Complex Liquid Mask; St. Clair: Hyaluronic Acid 100% Moisturizing Mask; and LADY MARIAN Beauty: White pearl whitening mask. The masks were applied to the skin for 15 minutes at the same time on different days. Skin hydration after using a commercially available facial mask product is approximately 37% to 55%. Compared with the dry-faced mask of the embodiment of the present invention, it was found that the dry-type mask of the first embodiment of the present invention can provide a skin with a high degree of moisturization (over 57%).

綜上所述,本創作之第一實施方式提供的乾敷型面膜,結合薄型發熱體與半固體凝膠層之結構,且半固體凝膠層之表層具有最高濃度之保溼成分。當敷用乾敷型面膜時,肌膚可直接接觸最高濃度之保溼成分,利於肌膚對保溼成分完整吸收。此外,透過加熱該乾敷型面膜,使得肌膚表面之溫度上升,增加肌膚的微血管微循環,可加速肌膚內的新陳代謝速率,增加肌膚含氧量。本創作提供之乾敷型面膜,可提供比人體體溫略高之溫度(37至41℃),此溫熱的效果亦能使毛孔張開,增加肌膚對皮膚外用劑的吸收效率。In summary, the dry-type mask provided by the first embodiment of the present invention combines the structure of a thin heating element and a semi-solid gel layer, and the surface layer of the semi-solid gel layer has the highest concentration of moisturizing component. When applied with a dry-faced mask, the skin can be directly exposed to the highest concentration of moisturizing ingredients, which is beneficial to the skin's complete absorption of the moisturizing ingredients. In addition, by heating the dry-faced mask, the temperature of the skin surface rises, and the microvascular microcirculation of the skin is increased, thereby accelerating the metabolism rate in the skin and increasing the oxygen content of the skin. The dry-coated mask provided by this creation can provide a slightly higher temperature (37 to 41 ° C) than the human body temperature. This warming effect can also open the pores and increase the absorption efficiency of the skin on the external preparation of the skin.

根據本創作之實施例,在此提供第二實施方式,其為利用本創作之實施例之發熱敷材結構製成一加熱痠痛貼布之實施方式。According to an embodiment of the present invention, a second embodiment is provided herein which is an embodiment in which a heated sore patch is formed using the heat-applied material structure of the embodiment of the present invention.

本創作之第二實施方式,請參閱第6圖,係為本創作之第二實施方式的加熱痠痛貼布之示意圖。第二實施方式提供一種加熱痠痛貼布40,其從貼布最外側之面至與肌膚接觸之面之結構依序為第二支撐層432、第二黏合層422、薄型發熱體410、第一黏合層420、第一支撐層430、半固體凝膠層440。In the second embodiment of the present invention, please refer to FIG. 6 , which is a schematic diagram of the heated sore patch of the second embodiment of the present invention. The second embodiment provides a heating and sore patch 40, wherein the structure from the outermost surface of the patch to the surface in contact with the skin is the second supporting layer 432, the second adhesive layer 422, the thin heating element 410, and the first The adhesive layer 420, the first support layer 430, and the semi-solid gel layer 440.

在此實施方式中,薄型發熱體410之材料與第一實施方式之材料相同。其主要包含鐵粉、鹽、活性碳、保水劑、蛭石與水組成之發熱成分。該些成分之比例為鐵粉:鹽:活性碳:保水劑:蛭石:水=6:1.2:1:1:1:3。然該比例僅為舉例說明,可不限於此。在本次實施方式中,薄型發熱體410之厚度為0.21 mm。In this embodiment, the material of the thin heating element 410 is the same as that of the first embodiment. It mainly contains iron powder, salt, activated carbon, water retention agent, vermiculite and water. The proportion of these ingredients is iron powder: salt: activated carbon: water retention agent: vermiculite: water = 6: 1.2:1:1:1:3. However, the ratio is merely illustrative and may not be limited thereto. In the present embodiment, the thickness of the thin heating element 410 is 0.21 mm.

接著,第一黏合層420及第二黏合層422主要用於將薄型發熱體410分別與第一支撐層430及第二支撐層432之一面結合。如前述本創作之另一實施例所述,第一黏合層420及第二黏合層422可包含化學纖維層(例如聚四氟乙烯材料所形成之防水透氣膜之夾層)、聚氨酯、丙烯酸類等黏著劑、或其組合。在本實施方式中,第一黏合層420及第二黏合層422僅以化學纖維層製成,利用化學纖維層形成上下層,分別接觸薄型發熱體410之兩面,使薄型發熱體410夾於兩層化學纖維層之間。在本次實施方式中,第一黏合層420及第二黏合層422之厚度個別皆為0.025 mm。Next, the first adhesive layer 420 and the second adhesive layer 422 are mainly used to directly bond the thin heating element 410 to one of the first support layer 430 and the second support layer 432. As described in another embodiment of the present invention, the first adhesive layer 420 and the second adhesive layer 422 may include a chemical fiber layer (for example, a sandwich of a waterproof and breathable film formed of a polytetrafluoroethylene material), polyurethane, acrylic, and the like. Adhesive, or a combination thereof. In the present embodiment, the first adhesive layer 420 and the second adhesive layer 422 are made only of a chemical fiber layer, and the upper and lower layers are formed by the chemical fiber layer, respectively contacting the two faces of the thin heat generating body 410, so that the thin heat generating body 410 is sandwiched between the two. Between layers of chemical fiber layers. In the present embodiment, the thicknesses of the first adhesive layer 420 and the second adhesive layer 422 are each 0.025 mm.

在此實施方式中,第一支撐層430及第二支撐層432用於支撐整體加熱痠痛貼布。如前所述,第一支撐層430及第二支撐層432可為化學纖維材料或天然纖維材料。化學纖維材料包含,但不限於,不織布、聚酯、尼龍等;天然纖維材料包含但不限於木漿、棉、麻、蠶絲、生物纖維等。在此加熱痠痛貼布40中,第一支撐層430及第二支稱層432為木漿料,且厚度均為0.13 mm。第一支撐層430及第二支撐層432形成袋體,將第一黏合層420、第二黏合層422及薄型發熱體410包覆,作為主體結構,主要用來維持之加熱痠痛貼布40形狀及穩定性。In this embodiment, the first support layer 430 and the second support layer 432 are used to support the overall heating sore patch. As previously mentioned, the first support layer 430 and the second support layer 432 can be chemical fiber materials or natural fiber materials. Chemical fiber materials include, but are not limited to, non-woven fabrics, polyesters, nylons, and the like; natural fiber materials include, but are not limited to, wood pulp, cotton, hemp, silk, bio-fibers, and the like. In the heated sore patch 40, the first support layer 430 and the second support layer 432 are wood pulp and have a thickness of 0.13 mm. The first support layer 430 and the second support layer 432 form a bag body, and the first adhesive layer 420, the second adhesive layer 422, and the thin heat generating body 410 are coated as a main structure, and are mainly used to maintain the shape of the heated sore patch 40. And stability.

進一步,半固體凝膠層440可包含固形物及水,根據本創作之實施例所述,固形物係選自由聚丙烯酸系、多元醇系、聚乙烯醇系(PVA)、聚乙烯基吡咯烷酮(PVP)、其組合物、其共聚物或其組合(例如聚苯乙酸丙烯酸共聚物)所組成之群組的親水性高分子材料,且該些親水性高分子材料之分子量大於1×10 5。在此實施方式中,半固體凝膠層440之厚度為1 mm。 Further, the semi-solid gel layer 440 may comprise a solid matter and water, and according to the embodiment of the present invention, the solid matter is selected from the group consisting of polyacrylic acid, polyhydric alcohol, polyvinyl alcohol (PVA), polyvinylpyrrolidone ( A hydrophilic polymer material of a group consisting of PVP), a composition thereof, a copolymer thereof, or a combination thereof (for example, a polyphenylacetic acid acrylic acid copolymer), and the molecular weight of the hydrophilic polymer materials is more than 1 × 10 5 . In this embodiment, the semi-solid gel layer 440 has a thickness of 1 mm.

此外,半固體凝膠層440另塗佈皮膚外用劑425。當半固體凝膠層440內含有皮膚外用劑425時,該些皮膚外用劑425的有效成分,可藉由化學分子間作用力滲入半固體凝膠層440中,而被固定於高分子聚合物中。此外,透過半固體凝膠層440之材料的正負電荷,以及該些高分子聚合物材料之分子量,使得皮膚外用劑425被於半固體凝膠層440上時,可被集中在半固體凝膠層440之表層,而使得半固體凝膠層440之表面呈現皮膚外用劑425的塗佈初始濃度。僅有少部分的皮膚外用劑325逐漸往半固體凝膠層340之底層遞減,形成濃度梯度之現象。在此加熱痠痛貼布之實施方式中,皮膚外用劑425主要為消炎止痛解熱等舒緩成分,舉例說明但不限於:Diclofenac、Indomethacin、Flurbiprofen、Ketoprofen、柳酸甲酯(Methyl Salicylate)等。Further, the semi-solid gel layer 440 is additionally coated with a skin external preparation 425. When the skin external preparation 425 is contained in the semi-solid gel layer 440, the active ingredients of the skin external preparation 425 can be infiltrated into the semi-solid gel layer 440 by chemical intermolecular force, and are fixed to the high-molecular polymer. in. In addition, the positive and negative charges of the material passing through the semi-solid gel layer 440, and the molecular weight of the high-molecular polymer materials, enable the skin external preparation 425 to be concentrated on the semi-solid gel when it is applied to the semi-solid gel layer 440. The surface layer of layer 440 is such that the surface of semi-solid gel layer 440 exhibits an initial coating concentration of skin external agent 425. Only a small portion of the skin external preparation 325 gradually decreases toward the bottom layer of the semi-solid gel layer 340, forming a concentration gradient phenomenon. In the embodiment in which the sore patch is heated, the skin external preparation 425 is mainly a soothing component such as anti-inflammatory, analgesic and antipyretic, and is exemplified by, but not limited to, Diclofenac, Indomethacin, Fluberiprofen, Ketoprofen, Methyl Salicylate and the like.

在此實施方式中,半固體凝膠層440之固形物包含下列材料:聚丙烯酸鈉(Sodium polyacrylate),分子量約為4×10 6,占總重量百分比為11.3%;聚乙烯基吡咯烷酮,分子量3×10 6,占總重量百分比為9%;吐溫(Tween) 80 (聚氧乙烯(20)-山梨醇酐單油酸酯),占總重量百分比9%。消炎止痛成分則包含Indomethacin,占總重量百分比0.5%;柳酸甲酯,占總重量百分比0.2%。半固體凝膠層440之含水率為:70%。 In this embodiment, the solid matter of the semi-solid gel layer 440 comprises the following material: sodium polyacrylate, having a molecular weight of about 4×10 6 , accounting for 11.3% by weight; polyvinylpyrrolidone, molecular weight 3 ×10 6 , 9% by weight of total weight; Tween 80 (polyoxyethylene (20)-sorbitan monooleate), 9% by weight. The anti-inflammatory analgesic ingredient contains Indomethacin, which is 0.5% by weight of the total weight; methyl salicylate, which is 0.2% by weight. The water content of the semi-solid gel layer 440 was 70%.

藉由紅外線光譜分析儀檢測本創作之加熱痠痛貼布40之半固體凝膠層440之內部的消炎止痛成分的濃度,本創作的加熱痠痛貼布40之半固體凝膠層440包含五個消炎止痛成分的濃度區間。若以半固體凝膠層440之表面(遠離薄型發熱體之面)為消炎止痛成分為100%計,則半固體凝膠層440之深度為距離表面0.5 mm之處的消炎止痛成分之濃度為72.5%;半固體凝膠層440之深度為距離表面1 mm之處的消炎止痛成分之濃度為63.1%;半固體凝膠層440之深度為距離表面1.5 mm之處的消炎止痛成分之濃度為45%;半固體凝膠層440之深度為距離表面2 mm之處的消炎止痛成分之濃度為11%。The concentration of the anti-inflammatory analgesic component inside the semi-solid gel layer 440 of the heated sore patch 40 of the present invention is detected by an infrared spectrum analyzer, and the semi-solid gel layer 440 of the heated sore patch 40 of the present invention contains five anti-inflammatory substances. The concentration interval of the analgesic component. If the surface of the semi-solid gel layer 440 (away from the surface of the thin heating element) is 100% of the anti-inflammatory analgesic component, the concentration of the semi-solid gel layer 440 is 0.5 mm from the surface, and the concentration of the anti-inflammatory analgesic component is 72.5%; the concentration of the semi-solid gel layer 440 is 63.1% of the anti-inflammatory analgesic component at a distance of 1 mm from the surface; and the concentration of the semi-solid gel layer 440 is 1.5 mm from the surface of the anti-inflammatory analgesic component. 45%; the depth of the semi-solid gel layer 440 is 11% of the anti-inflammatory analgesic component at a distance of 2 mm from the surface.

進一步,當使用本創作第二實施方式的加熱痠痛貼布40時,將該貼布從包裝袋體取出並簡易搓揉,使薄型發熱體410開始釋放熱能並傳導至半固體凝膠層440。薄型發熱體410之發熱溫度為43℃。當使用時,半固體凝膠層440遠離薄型發熱體之一面與患部肌膚貼合,實際測量半固體凝膠層440表面之溫度為比人體體溫略高之溫度,大約在37至41℃。加熱痠痛貼布40除了可透過薄型發熱體達成加熱至適合直接接觸肌膚使用的溫度之外,亦可維持該溫度一段特定時間,例如可維持大約50分鐘至70分鐘。Further, when the heated sore patch 40 of the second embodiment of the present invention is used, the patch is taken out from the package body and simply smashed, and the thin heating element 410 starts to release heat energy and is conducted to the semi-solid gel layer 440. The heat generation temperature of the thin heating element 410 was 43 °C. When in use, the semi-solid gel layer 440 is adhered to the skin of the affected part away from one side of the thin heating element, and the temperature of the surface of the semi-solid gel layer 440 is actually measured to be slightly higher than the body temperature of the body, which is about 37 to 41 °C. The heated sore patch 40 can be maintained at a temperature for a specific period of time, for example, for a period of about 50 minutes to 70 minutes, in addition to being heated by a thin heat generating body to a temperature suitable for direct contact with the skin.

實際使用時,由於薄型發熱體提供至半固體凝膠層的熱能,可使得於貼附於患部肌膚時,給予患部肌膚局部熱敷功能,促使局部血液循環。此外,呈現濃度梯度分布的消炎止痛成分,可同時於微溫環境下,拓人體體溫略高之溫度,如第成,製作發熱體夾於兩層化學纖維層之間, diffiency, osed on the second/oppsite tation 1,  1 should be provided with nolvolty.  entable i增加經皮吸收的效率。In actual use, the thin heat generating body provides thermal energy to the semi-solid gel layer, so that when applied to the affected part skin, the skin of the affected part is locally applied with heat to promote local blood circulation. In addition, the anti-inflammatory and analgesic component exhibiting a concentration gradient distribution can simultaneously expand the body temperature to a slightly higher temperature in a micro-temperature environment, such as the first generation, and the heating element is sandwiched between the two chemical fiber layers, diffiency, osed on the second /oppsite tation 1, 1 should be provided with nolvolty. entable i increases the efficiency of transdermal absorption.

綜合上述,本創作提供一種發熱敷材結構,其結合薄型發熱體與具有以親水性高分子材料形成之半固體凝膠層,皮膚外用劑以最高濃度維持集中於半固體凝膠層之表面,可利於使用者直接吸收高濃度之皮膚外用劑。再者,本創作提供之發熱敷材結構,可穩定使該敷材維持一定熱度,增加使用上的舒適性,增加肌膚對活性成分之經皮吸收率,並且達到熱敷效應,可舒緩傷病部位。最後,藉由薄型發熱體加熱,達到緩釋效應,可延長皮膚外用劑之釋放時間,可促使滲透進半固體凝膠層內部之較低的皮膚外用劑繼而可被肌膚吸收,大幅增加皮膚外用劑之吸收效率,減少皮膚外用劑的浪費。In summary, the present invention provides a heat-producing structure which combines a thin heating element and a semi-solid gel layer formed of a hydrophilic polymer material, and the external preparation for skin is maintained at a concentration of the semi-solid gel layer at the highest concentration. It can help the user to directly absorb high concentration of skin external preparation. Furthermore, the structure of the heat-applied material provided by the present invention can stably maintain the heat of the dressing, increase the comfort of use, increase the transdermal absorption rate of the active ingredient, and achieve the hot compress effect, so as to relieve the wounded part. Finally, by the heating of the thin heating element, the sustained release effect is achieved, and the release time of the external preparation for the skin can be prolonged, and the lower external skin preparation which penetrates into the semi-solid gel layer can be absorbed by the skin, thereby greatly increasing the external application of the skin. The absorption efficiency of the agent reduces the waste of the external preparation of the skin.

以上所述僅為舉例性,而非限制性者。任何未脫離本創作之精神與範疇,而對等進行之等效修改或變更,均應包含於後附之申請專利範圍中。The foregoing is illustrative only and not limiting. Any equivalent modifications or changes made without departing from the spirit and scope of this creation shall be included in the scope of the appended patent application.

10、20‧‧‧發熱敷材結構
30‧‧‧乾敷型面膜
40‧‧‧加熱痠痛貼布
110、210、310、410‧‧‧薄型發熱體
120、220、340、440‧‧‧半固體凝膠層
125、225、325、425‧‧‧皮膚外用劑
240、320、420‧‧‧第一黏合層
230、330、430‧‧‧第一支撐層
422‧‧‧第二黏合層
432‧‧‧第二支撐層
10, 20‧‧‧Fever material structure
30‧‧‧ dry mask
40‧‧‧heating sore patch
110, 210, 310, 410‧‧‧ thin heating elements
120, 220, 340, 440‧‧‧ semi-solid gel layer
125, 225, 325, 425‧ ‧ skin external preparations
240, 320, 420‧‧‧ first adhesive layer
230, 330, 430‧‧‧ first support layer
422‧‧‧Second adhesive layer
432‧‧‧second support layer

第1圖係為根據本創作之一實施例的發熱敷材結構示意圖。Fig. 1 is a schematic view showing the structure of a heat-generating material according to an embodiment of the present invention.

第2圖係為根據本創作之一實施例的半固體凝膠層之深度與皮膚外用劑濃度之分布關係圖。Fig. 2 is a graph showing the relationship between the depth of the semi-solid gel layer and the concentration of the external preparation for skin according to an embodiment of the present invention.

第3圖係為根據本創作之另一實施例的發熱敷材結構示意圖。Fig. 3 is a schematic view showing the structure of a heat-generating material according to another embodiment of the present invention.

第4圖係為根據本創作之第一實施方式的乾敷型面膜之結構示意圖。Fig. 4 is a schematic view showing the structure of a dry-type mask according to the first embodiment of the present invention.

第5圖係為描述半固體凝膠層中活性成分之擴散示意圖。Figure 5 is a schematic diagram showing the diffusion of active ingredients in a semi-solid gel layer.

第6圖係為根據本創作之第二實施方式的加熱痠痛貼布之示意圖。Figure 6 is a schematic view of a heated sore patch according to a second embodiment of the present invention.

10‧‧‧發熱敷材結構 10‧‧‧Fever material structure

110‧‧‧薄型發熱體 110‧‧‧Small heating element

120‧‧‧半固體凝膠層 120‧‧‧ semi-solid gel layer

125‧‧‧皮膚外用劑 125‧‧‧ Skin external preparation

Claims (11)

一種發熱敷材結構,其包含: 一薄型發熱體,其厚度為小於5 mm;以及 一半固體凝膠層,其包含第一面及第二面,該半固體凝膠層之該第一面與該薄型發熱體貼合, 其中該半固體凝膠層包含一皮膚外用劑,該皮膚外用劑於該半固體凝膠層之該第二面具有一第一濃度,於該半固體凝膠層之該第一面具有一第二濃度,且該第一濃度大於該第二濃度。A heat-generating material structure comprising: a thin heat generating body having a thickness of less than 5 mm; and a semi-solid gel layer comprising a first side and a second side, the first side of the semi-solid gel layer The thin heat generating body is laminated, wherein the semi-solid gel layer comprises a skin external preparation, and the skin external preparation has a first concentration on the second mask of the semi-solid gel layer, and the semi-solid gel layer is The first mask has a second concentration and the first concentration is greater than the second concentration. 如申請專利範圍第1項所述之發熱敷材結構,其進一步包含於半固體凝膠層的該第一面及該第二面之間具有該皮膚外用劑之一第三濃度。The heat-generating material structure according to claim 1, further comprising a third concentration of the skin external preparation between the first surface and the second surface of the semi-solid gel layer. 如申請專利範圍第2項所述之發熱敷材結構,其中該第一濃度大於該第三濃度,該第三濃度大於該第二濃度。The heat-producing structure of claim 2, wherein the first concentration is greater than the third concentration, and the third concentration is greater than the second concentration. 如申請專利範圍第3項所述之發熱敷材結構,其中該第一濃度與該第二濃度之差值至少大於20%。The heat-producing structure of claim 3, wherein the difference between the first concentration and the second concentration is at least greater than 20%. 如申請專利範圍第1項所述之發熱敷材結構,其中該半固體凝膠層包含一固形物及水。The heat-producing structure of claim 1, wherein the semi-solid gel layer comprises a solid and water. 如申請專利範圍第5項所述之發熱敷材結構,其中該固形物係包含選自聚丙烯酸系、多元醇系、聚乙烯醇系、聚乙烯基吡咯烷酮、其共聚物、其組合物及其組合的群組的親水性高分子材料,其中該親水性高分子材料之分子量大於1×10 5The heat-generating material structure according to claim 5, wherein the solid material comprises a polyacrylic acid, a polyol, a polyvinyl alcohol, a polyvinylpyrrolidone, a copolymer thereof, a composition thereof, and A combined group of hydrophilic polymeric materials, wherein the hydrophilic polymeric material has a molecular weight greater than 1 x 10 5 . 如申請專利範圍第6項所述之發熱敷材結構,其中該固形物占該半固體凝膠層之總重量百分比為1%至70%。The heat-generating material structure according to claim 6, wherein the solid content is from 1% to 70% by weight based on the total weight of the semi-solid gel layer. 如申請專利範圍第5項所述之發熱敷材結構,其中該半固體凝膠層之含水率為30%至99%。The heat-generating material structure according to claim 5, wherein the semi-solid gel layer has a water content of 30% to 99%. 如申請專利範圍第1項所述之發熱敷材結構,其進一步包含: 一第一支撐層,設置於該半固體凝膠層與該薄型發熱體之間;以及 一第一黏合層,設置於該第一支撐層與該薄型發熱體之間。The heat-generating material structure according to claim 1, further comprising: a first support layer disposed between the semi-solid gel layer and the thin heat generating body; and a first adhesive layer disposed on The first support layer is between the thin heating element. 如申請專利範圍第5項所述之發熱敷材結構,其進一步包含: 一第二支撐層,設置於該薄型發熱體面對該第一黏合層之相對面;以及 一第二黏合層,係設置於該第二支撐層與該薄型發熱體之間。The heat-generating material structure according to claim 5, further comprising: a second supporting layer disposed on an opposite side of the thin heating element facing the first bonding layer; and a second bonding layer And disposed between the second supporting layer and the thin heating element. 如申請專利範圍第1項所述之發熱敷材結構,其中該薄型發熱體之發熱溫度為28℃至45℃。The heat-generating material structure according to claim 1, wherein the heat-generating temperature of the thin-type heat-generating body is from 28 ° C to 45 ° C.
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