TWM464658U - Biological detection lamp box - Google Patents
Biological detection lamp box Download PDFInfo
- Publication number
- TWM464658U TWM464658U TW102208441U TW102208441U TWM464658U TW M464658 U TWM464658 U TW M464658U TW 102208441 U TW102208441 U TW 102208441U TW 102208441 U TW102208441 U TW 102208441U TW M464658 U TWM464658 U TW M464658U
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- Taiwan
- Prior art keywords
- substrate
- biological sample
- light box
- light
- biodetection
- Prior art date
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- 238000001514 detection method Methods 0.000 title claims description 19
- 239000000758 substrate Substances 0.000 claims description 32
- 239000012472 biological sample Substances 0.000 claims description 30
- 239000011521 glass Substances 0.000 claims description 25
- 239000007850 fluorescent dye Substances 0.000 claims description 15
- 239000011248 coating agent Substances 0.000 claims description 8
- 238000000576 coating method Methods 0.000 claims description 8
- 230000005284 excitation Effects 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 238000012360 testing method Methods 0.000 description 5
- 238000009500 colour coating Methods 0.000 description 2
- 238000001917 fluorescence detection Methods 0.000 description 2
- 238000011045 prefiltration Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
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- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Description
本創作係與生物檢測設備有關；特別是指一種生物檢測燈箱。This creative department is related to biological testing equipment; in particular, it is a biological testing light box.
螢光檢測法(fluorescence detection)是目前生物科技領域中，對於檢驗生物樣本中所存在的特定分子，較為簡單，也是最為廣泛使用的檢測方法之一。螢光檢測法係在待檢測的生物樣本中加入特定的螢光染料染色，再以具有特定波長的光線照射生物樣本，以激發其中的螢光染料，產生特定波長的光，讓研究人員可以肉眼觀測。Fluorescence detection is currently one of the most widely used detection methods for the detection of specific molecules present in biological samples in the field of biotechnology. Fluorescence detection method is to add a specific fluorescent dye to the biological sample to be detected, and then irradiate the biological sample with light having a specific wavelength to excite the fluorescent dye therein to generate light of a specific wavelength, so that the researcher can have the naked eye. Observation.
傳統用於螢光檢測法之生物檢測燈箱，具有一個放置生物樣本的承載區，該承載區具有一透明的基板，通常是以玻璃製成，該基板頂面供放置生物樣本，而該基板的下方會設置一黑色的背景板，通常是以泡棉或塑膠板製成，該背景板的頂面則形成一黑色的背景面供與生物樣本受激後產生的螢光產生對比，讓研究人員觀測。A biological detection light box conventionally used for fluorescent detection has a carrying area for placing a biological sample, the carrying area having a transparent substrate, usually made of glass, the top surface of the substrate for placing a biological sample, and the substrate is A black background plate is placed below, usually made of foam or plastic sheet, and the top surface of the background plate forms a black background surface for contrast with the fluorescence generated by the biological sample being stimulated, allowing researchers Observation.
然而，傳統的生物檢測燈箱之基板與背景板間並非完全地密合，因此，基板的底面與背景面之間具有縫隙存在。而生物樣本係含有水份，部分的水份會由縫隙滲入基板與背景面之間，而不易清理。如此，不但不美觀，更甚者在基板與背景面的之間產生發霉的情形，而造成觀測上的誤差。However, the substrate of the conventional bio-detection light box is not completely adhered to the background plate, and therefore, there is a gap between the bottom surface of the substrate and the background surface. The biological sample contains water, and part of the water will penetrate between the substrate and the background surface by the gap, so it is not easy to clean. In this way, not only is it not beautiful, but even a moldy situation occurs between the substrate and the background surface, resulting in an error in observation.
有鑑於此，本創作之目的在於提供一種生物檢測燈箱，可避免水滲入基板與背景面間。In view of this, the purpose of the present invention is to provide a biological detection light box that prevents water from penetrating between the substrate and the background surface.
緣以達成上述目的，本創作所提供之生物檢測燈箱，用以檢測已加入螢光染料的生物樣本，包含有一主體、一具有顏色的基板與一光源模組。其中，該基板設於該主體之一表面上，該基板具有一頂面供承放該生物樣本；該光源模組用以提供激發螢光染料的特徵波長附近範圍的光線並照射在該生物樣本上。In order to achieve the above object, the biodetection light box provided by the present invention is for detecting a biological sample to which a fluorescent dye has been added, and comprises a main body, a colored substrate and a light source module. The substrate is disposed on a surface of the main body, the substrate has a top surface for receiving the biological sample, and the light source module is configured to provide light of a range near a characteristic wavelength of the excitation fluorescent dye and irradiate the biological sample on.
本創作更提供另一生物檢測燈箱，包含有一主體、一基板與一光源模組。其中：該基板設於該主體之一表面上，該基板具有一頂面與一底面，該生物樣本係放置於該基板的頂面；一非透明的塗層係附著於該基板的底面；該光源模組用以提供激發螢光染料的特徵波長附近範圍的光線並照射在該生物樣本上。The present invention further provides another biological detection light box, comprising a main body, a substrate and a light source module. Wherein: the substrate is disposed on a surface of the main body, the substrate has a top surface and a bottom surface, the biological sample is placed on the top surface of the substrate; and a non-transparent coating is attached to the bottom surface of the substrate; The light source module is configured to provide light that excites a range of characteristic wavelengths of the fluorescent dye and illuminate the biological sample.
藉此，透過該生物檢測燈箱之設計，不會有如傳統之生物檢測燈箱水滲入基板與背景面之間的問題產生。Thereby, through the design of the biological detection light box, there is no problem that the traditional biological detection light box water penetrates between the substrate and the background surface.
1‧‧‧生物檢測燈箱1‧‧‧Biology test light box
10‧‧‧主體10‧‧‧ Subject
12‧‧‧底座12‧‧‧Base
14‧‧‧表面14‧‧‧ surface
16‧‧‧凹槽16‧‧‧ Groove
18‧‧‧側牆18‧‧‧ Side wall
182‧‧‧開口182‧‧‧ openings
184‧‧‧固定槽184‧‧‧fixed slot
20‧‧‧頂板20‧‧‧ top board
202‧‧‧開口202‧‧‧ openings
22‧‧‧後濾光件22‧‧‧ Rear filter
24‧‧‧光源模組24‧‧‧Light source module
26‧‧‧前濾光件26‧‧‧Pre-filter
28‧‧‧激發光源28‧‧‧Excitation source
30‧‧‧黑色玻璃板30‧‧‧Black glass plate
302‧‧‧頂面302‧‧‧ top surface
2‧‧‧生物檢測燈箱2‧‧‧Biological test light box
32‧‧‧玻璃板32‧‧‧ glass plate
322‧‧‧頂面322‧‧‧ top surface
324‧‧‧底面324‧‧‧ bottom
34‧‧‧塗層34‧‧‧Coating
S‧‧‧生物樣本S‧‧ biological samples
圖1為本創作第一較佳實施例生物檢測燈箱部分分解之立體圖；圖2為本創作第一較佳實施例生物檢測燈箱燈箱之另一立體圖；以及圖3為本創作第一較佳實施例生物檢測燈箱之應用示意圖。1 is a partially exploded perspective view of the bio-detection light box of the first preferred embodiment of the present invention; FIG. 2 is another perspective view of the bio-detection light box light box of the first preferred embodiment; and FIG. 3 is a first preferred embodiment of the present invention. A schematic diagram of the application of a biometric light box.
圖4為本創作第二較佳實施例生物檢測燈箱之應用示意圖。4 is a schematic view showing the application of the biological detection light box of the second preferred embodiment of the present invention.
為能更清楚地說明本創作，茲舉較佳實施例並配合圖示詳細說明如后，圖1至圖3所示者為本創作第一較佳實施之生物檢測燈箱1，用以檢測已加入螢光染料的生物樣本S。該生物檢測燈箱1包含有一主體10，二光源模組24與一以黑色玻璃板30為例的基板。In order to explain the present invention more clearly, the preferred embodiment will be described in detail with reference to the drawings. As shown in FIG. 1 to FIG. 3, the bio-detection light box 1 of the first preferred embodiment is used for detecting A biological sample S of fluorescent dye is added. The bio-detection light box 1 includes a main body 10, two light source modules 24 and a substrate exemplified by a black glass plate 30.
該主體10具有一底座12以及位於底座12兩端呈直立狀的二側牆18。該底座12上的一表面14凹陷形成有一呈矩形狀的凹槽16。在該二側牆18的內側分別設有一開口182。各該側牆18內側設置有二固定槽184，該二固定槽184位於各該開口182兩側。此外，其中一側牆18的頂側樞設有一頂板20，該頂板20具有一開口202，在該頂板20上裝設有一後濾光件22，該後濾光件22以可替換的方式結合於該頂板20且設於該開口202。The body 10 has a base 12 and two side walls 18 that are upright at both ends of the base 12. A surface 14 of the base 12 is recessed to define a recess 16 in the shape of a rectangle. An opening 182 is defined in each of the inner sides of the two side walls 18. Two fixing slots 184 are disposed on the inner side of each of the side walls 18, and the two fixing slots 184 are located on opposite sides of each of the openings 182. In addition, a top plate 20 is pivotally disposed on a top side of the side wall 18, and the top plate 20 has an opening 202. The top plate 20 is provided with a rear filter member 22, and the rear filter member 22 is coupled in an alternative manner. The top plate 20 is disposed in the opening 202.
該二光源模組24分別設置於該二側牆18中，各該光源模組包括有一前濾光件26與一激發光源28。各該前濾光件26可抽換地由各該開口182上方插設於該二固定槽184中。各該激發光源28設置於各該側牆18內且位於各該前濾光件26的後方。The two light source modules 24 are respectively disposed in the two side walls 18, and each of the light source modules includes a front filter member 26 and an excitation light source 28. Each of the front filter members 26 is detachably inserted into the two fixing slots 184 from above the openings 182. Each of the excitation light sources 28 is disposed in each of the side walls 18 and behind the front filter members 26 .
在本實施例中，該激發光源28具有若干藍光LED。另外在主體10中設置有讓藍光LED發光的相關設備，例如：電源、變壓器、整流器、開關等電子電路裝置，並未顯示於圖中。前述之設備並非本案的的主要特點，閱讀本創作的人士亦可輕易的找到此等設備的相關技術，在此容不贅述其詳細結構。In this embodiment, the excitation source 28 has a plurality of blue LEDs. In addition, a related device for causing the blue LED to emit light, such as an electronic circuit device such as a power source, a transformer, a rectifier, a switch, etc., is provided in the main body 10, and is not shown in the figure. The aforementioned equipment is not the main feature of the case. Those who read this book can also easily find the related technologies of these devices, and the detailed structure thereof will not be described here.
該黑色玻璃板30係呈長矩形，設於該底座12的凹槽16中。該黑色玻璃板30的頂面302供放置該生物樣本S。在本實施例中，該黑色玻璃板30為不透光，因此， 該黑色玻璃板30之頂面302則形成一黑色的背景面，可與該生物樣本S中螢光染料受激發後的光線顏色產生對比，讓研究人員可更清楚的以肉眼觀察。The black glass plate 30 has a long rectangular shape and is disposed in the recess 16 of the base 12. The top surface 302 of the black glass sheet 30 is for placing the biological sample S. In this embodiment, the black glass plate 30 is opaque, therefore, The top surface 302 of the black glass sheet 30 forms a black background surface which is contrasted with the color of the fluorescent dye in the biological sample S, so that the researchers can more clearly observe with the naked eye.
請參閱圖3所示，該激發光源28所產生的光線進入該前濾光件26，且為前濾光件26過濾後透出，其中，該前濾光件26透出的光線為可激發加入該生物樣本S中的螢光染料之特徵波長附近範圍的光線。該前濾光件26透出的光線照射在該生物樣本S上，激發該生物樣本S中的螢光染料，受激後的光線由後濾光件22射出，研究人員可由該頂板20的開口2觀察該生物樣本S。Referring to FIG. 3, the light generated by the excitation light source 28 enters the front filter member 26, and is filtered by the front filter member 26, wherein the light transmitted from the front filter member 26 is excitable. The light in the vicinity of the characteristic wavelength of the fluorescent dye in the biological sample S is added. The light emitted from the front filter member 26 is irradiated onto the biological sample S to excite the fluorescent dye in the biological sample S. The excited light is emitted by the rear filter member 22, and the researcher can open the opening of the top plate 20. 2 Observe the biological sample S.
在實務上，如使用不同的螢光染料，則所需的前濾光件與後濾光件的特性以及玻璃板的顏色也會跟著螢光染料有所調整。此時，研究人員僅需選擇適當的前濾光件、後濾光件，以及相對應顏色的玻璃板，即可達到相同的效果，必要時更可省略後濾光件及頂板的設置。In practice, if different fluorescent dyes are used, the characteristics of the desired front and rear filters and the color of the glass will also be adjusted with the fluorescent dye. At this point, the researcher only needs to select the appropriate front filter, the rear filter, and the corresponding color of the glass plate to achieve the same effect, if necessary, the rear filter and the top plate can be omitted.
在上述中，由於背景面係為該黑色玻璃板30的頂面302，因此，不會有如傳統的基板發生水滲入背景面與玻璃板之間而無法清除的情況發生。即使該生物樣本S滲水，也可很容易清理該黑色玻璃板30的頂面302。In the above, since the background surface is the top surface 302 of the black glass plate 30, there is no possibility that water may penetrate between the background surface and the glass plate as in the conventional substrate and cannot be removed. Even if the biological sample S seeps, the top surface 302 of the black glass sheet 30 can be easily cleaned.
圖4所示者為本創作第二較佳實施例之生物檢測燈箱2，其具有大致相同於上述第一實施例之結構，不同的是，本實施例的基板為一透明的玻璃板32，該玻璃板32具有一頂面322與一底面324，該玻璃板32底面324設置有一非透明且具有特定顏色的塗層34，本實施例中，該塗層34為黑色塗料附著於該玻璃板32之底面324所形成者，藉此，該塗層34即形成一背景面。至於該生物樣本S則放置於該玻璃板32的頂面32a。The biodetection light box 2 of the second preferred embodiment of the present invention is substantially the same as the structure of the first embodiment described above, except that the substrate of the embodiment is a transparent glass plate 32. The glass plate 32 has a top surface 322 and a bottom surface 324. The bottom surface 324 of the glass plate 32 is provided with a opaque and specific color coating 34. In this embodiment, the coating 34 is a black paint attached to the glass plate. The bottom surface 324 of 32 is formed whereby the coating 34 forms a background surface. The biological sample S is placed on the top surface 32a of the glass plate 32.
由於該塗層34係直接附著於該玻璃板32的底 面324，因此該塗層34與該玻璃板32之間並無縫隙存在，如此，便不存在該生物樣本S的水份滲入塗層34與玻璃板32之間的問題。在實務上，可視生物樣本受激後的螢光顏色而選擇設置不同顏色之塗層的玻璃板，以形成不同顏色的背景面。Since the coating 34 is directly attached to the bottom of the glass plate 32 Face 324, so that there is no gap between the coating 34 and the glass sheet 32, so that there is no problem that the moisture of the biological sample S penetrates between the coating 34 and the glass sheet 32. In practice, it is possible to select a glass plate of a different color coating to visualize the fluorescent color of the biological sample to form a different color background.
據上所述，本創作之生物檢測燈箱可有效避免水分殘留於背景面上無法清除，而造成不美觀，甚致發霉的情形而影響觀測結果。以上所述僅為本創作較佳可行實施例而已，本創作的重點在於高檢測對比之燈箱，該生物樣本僅是用以說明本創作而己。舉凡應用本創作說明書及申請專利範圍所為之等效變化，理應包含在本創作之專利範圍內。According to the above, the bio-detection light box of the present invention can effectively prevent the water from remaining on the background surface and cannot be removed, resulting in an unsightly condition, which may affect the observation result. The above description is only a preferred embodiment of the present invention. The focus of this creation is on a light box with high detection contrast, which is only used to illustrate the creation. Equivalent changes in the scope of the application and the scope of the patent application should be included in the scope of the patent.
1‧‧‧生物檢測燈箱1‧‧‧Biology test light box
10‧‧‧主體10‧‧‧ Subject
12‧‧‧底座12‧‧‧Base
14‧‧‧表面14‧‧‧ surface
16‧‧‧凹槽16‧‧‧ Groove
18‧‧‧側牆18‧‧‧ Side wall
182‧‧‧開口182‧‧‧ openings
184‧‧‧固定槽184‧‧‧fixed slot
20‧‧‧頂板20‧‧‧ top board
202‧‧‧開口202‧‧‧ openings
22‧‧‧後濾光件22‧‧‧ Rear filter
24‧‧‧光源模組24‧‧‧Light source module
26‧‧‧前濾光件26‧‧‧Pre-filter
28‧‧‧激發光源28‧‧‧Excitation source
30‧‧‧黑色玻璃板30‧‧‧Black glass plate
302‧‧‧頂面302‧‧‧ top surface
Claims (8)
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW102208441U TWM464658U (en) | 2013-05-07 | 2013-05-07 | Biological detection lamp box |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW102208441U TWM464658U (en) | 2013-05-07 | 2013-05-07 | Biological detection lamp box |
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| Publication Number | Publication Date |
|---|---|
| TWM464658U true TWM464658U (en) | 2013-11-01 |
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| TW102208441U TWM464658U (en) | 2013-05-07 | 2013-05-07 | Biological detection lamp box |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115279882A (en) * | 2020-03-09 | 2022-11-01 | 奥瑞生物技术有限公司 | Bioreactor for cell treatment |
-
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115279882A (en) * | 2020-03-09 | 2022-11-01 | 奥瑞生物技术有限公司 | Bioreactor for cell treatment |
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| Date | Code | Title | Description |
|---|---|---|---|
| MM4K | Annulment or lapse of a utility model due to non-payment of fees |