TWM461415U - A high efficient uv and blue light cross-link corneal photo-therapy device - Google Patents

Abstract

This invention provides a high efficient corneal therapy system using UV and blue light collagen cross-link. The said UV-blue therapy system consists of a control panel, a power supply, and a light source. The output light of the said light source is delivered to the treated cornea via an optical set and having a spot size of 7 to 15 mm. The said light source can be a LED or a diode laser having a wavelength range of 340 to 480 nm, power of 3 mW to 500 mW. The said UV-blue therapy system can also consists of multiple channels. It can also consists of a fixation post set consisting of a pair of posts, or a standing-light soft-post, or an M-shape post. The output light can be a single wavelength (340-480 nm) or a dual wavelength combining (340-380) nm and (381-480) nm. The said UV-blue therapy system may be used for keratoconus and also used to stabilize the cornea surface curvature after a laser vision correction.

Description

High-efficiency keratophototherapy apparatus using purple blue cross-linking

This creation is about an ophthalmic phototherapy instrument, especially a high-efficiency keratophototherapy device that uses violet-blue cross-linking. The violet phototherapy device combines Riboflavine photosensitizers for the treatment of corneal vertebral vertebral (keratoconus) and for stabilizing corneal surface curvature after laser vision correction.

The use of ultraviolet (UV) collagen crosslinks has been used for many years to treat stabilization of the keratoconus and laser vision correction (LASIK). The current technology uses an ultraviolet power density of about 3 milliwatts (per unit square centimeter), and the treatment takes about 30 minutes. Furthermore, the current technology uses a continuous light-emitting LED ultraviolet (wavelength of about 365 nm) light source, and its ultraviolet light energy penetration depth is limited. Current technology is also limited to monocular treatment with a single wavelength and a single source.

In view of the above prior art background, the purpose of the present work is to propose a new ophthalmic violet-blue (UV-blue) phototherapy apparatus, in combination with a riboflavin photosensitizer, to eliminate the disadvantages of the prior art described above. The Ophthalmic Violet Blue Light Therapy of the present invention comprises a panel control display, a power supply and a light source, the light output of the light source controlling the size of the spot at the corneal treatment site via an optical lens set, the diameter of which ranges from 7 to 15 mm. The light source can be an LED (light emission diode) or a semiconductor laser (diode laser) having an output wavelength of 340 to 480 nm (including ultraviolet light and blue light). Light), either continuous or pulsed, with an output frequency of 1 to 1,000 Hertz (Hz) and an output power of 3 to 500 milliwatts at the treatment site. The violet light therapy device can also be multi-channel output, allowing two or more corneas or patients to be performed simultaneously.

The violet light therapy device also includes a fixed bracket comprising: a vertical and a lateral bracket, a conventional vertical light hose bracket or an M-shaped bracket. The violet light therapy device includes the output light as a single wavelength or a dual wavelength. The dual wavelength can be combined with 340 to 380 nm and 381 to 480 nm to accelerate and increase the efficacy of corneal violet blue cross-linking. The violet blue keratophototherapy apparatus can be used to treat corneal vertebral vertebral (keratoconus), and can also be used to stabilize the corneal surface curvature after laser vision correction. The purpose of this creation can be achieved by the following specific examples.

(10)‧‧‧Power supply

(11,12)‧‧‧ Panel Control Display

(13)‧‧‧Manual switch

(14)‧‧‧ Foot switch

(15)‧‧‧Power cord

(20)‧‧‧Light source

(30)‧‧‧Optical lens group

(21)‧‧‧ Output light

(22)‧‧‧Glenoptic lens

(22) ‧‧‧ positive lens

(32)‧‧‧negative lens

(71,72)‧‧‧M-shaped bracket

(81,82)‧‧‧Scan optical lens set

Figure 1 is a schematic diagram of the planar structure of the system of the present creation.

Figure 2 is a schematic view of the optical lens set of the present invention.

Figure 3 is a spectrum of absorption of a riboflavin photoreceptor.

Figure 4 is a schematic diagram of the dual pipe output plane structure of the present creation.

Figure 5 is a schematic view showing the structure of a fixed bracket of the present invention.

Fig. 6 is a schematic view showing the structure of another M-shaped fixing bracket of the present invention.

FIG. 7 is a schematic structural diagram of another scanning system of the present invention.

Example 1:

As shown in Figure-1, the creative department provides a purple light therapy device, which includes: a power supply (10) and panel control display (11, 12), the power supply (10) is connected to the light source (20) via a power line (15), and the light output of the light source (20) is controlled via the optical lens set (30) It outputs the size of the spot at the site being treated. The control of the illumination time of the violet light therapy device includes: a manual switch (13), a panel control (11) or a foot switch (14). The panel control parameters include: output light illumination time display (11), output light power display (12), and illumination mode. The irradiation mode may be continuous or pulsed, the pulse width is 0.001 second to 2 seconds, and the irradiation time ranges from 60 seconds to 600 seconds.

As shown in FIG. 2, the optical lens group (30) changes the spot size of the output light (21) at the site to be treated via a positional movement distance (L) of the poly lens (22), and the spot size can also be different from the treated site. The position depends on the position (R1, R2). As shown in FIG. 2, the optical lens group may also include a set of positive lens (22) and negative lens (32), and the spot size is adjusted by a negative lens (32) position moving distance (L). The above-mentioned polylens (22), positive lens (22) and negative lens (32) have a focal length ranging from 0.5 to 10 cm, and the spot has a diameter ranging from 7 to 15 mm at the site to be treated.

As shown in Figure-3, the light sensitizer Riboflavine absorption spectrum defines the desired output purple-blue wavelength of the light source (20) is 340 to 480 nm, and the light source (20) can be LED (light emission diode) or semiconductor laser (diode laser), the output light wavelength is 340 to 480 nm, can be continuous light output or pulsed light output, the output frequency is 1 to 1,000 Hz, the output power is treated The location is from 3 milliwatts to 500 milliwatts. The treatment site is a riboflavin-coated cornea having a surface diameter ranging from 7 to 15 mm. The corneal collagen is used for the treatment of corneal keratoconus and the stabilization of laser vision correction via violet blue cross-linking.

Example 2:

As shown in Figure-4, the violet blue light therapy device is a multi-channel output that can perform two or more corneas or patients simultaneously. The dual pipe output ultraviolet light irradiation time can be controlled by a switch (103, 104) or by a panel (101, 102), respectively. The light source (20) can also be coupled to an optical fiber and a handle having an optical lens set (30) via a fiber optic coupler (not shown in Figure 4) (not shown in Figure 4).

Example 3:

As shown in Figure-5, the purple light therapy device also includes a fixed bracket consisting of a vertical and a lateral bracket for lateral distance adjustment and height (H) adjustment at the corneal surface (60) spot. size. The fixing bracket may also include a conventional standing lamp hose bracket (shown on the right in FIG. 5).

The mounting bracket can also include an M-shaped bracket (71, 72) as shown in Figure -6, which can be directly attached to the patient's head (80), as is known in the art of wearing glasses, with the light source (20) and the corneal surface (60). The height of -1, 60-2) can be adjusted via the height of the bracket (72). The light source (20) can be a single pipe or a dual pipe output. Figure 6 shows the dual pipe output.

Example 4:

As shown in Fig. 7, the violet light therapy device comprises a light source (20) whose output light (21) is controlled by a pair of scanning optical lens groups (81, 82) to scan a diameter range of 7 at the site to be treated (60). To 15 mm. The scanning light (21) should be parallel or nearly parallel, with a spot diameter of 0.5 to 2.0 mm.

Example 5:

The purple light therapy device shown in this creation includes a single power supply connected to a single light source, or a single power supply connected to two light sources, or two power supplies connected to two light sources. The output light of the single light source or the two light sources comprises: a same wavelength of a wavelength range of 340 to 480 nm; or a single source of a wide spectrum (spectrum width of 20 to 100 nm) having a center wavelength of 380 to 460 nm; Wavelength A combination of any two different wavelengths from 340 to 480 nm. The dual wavelength combination (or the single source of the broad spectrum) has two different (or a wide range) photosensing absorption values (A), so that the output light can simultaneously reach different light energy penetration depths d=1/A (A small value of penetration is high), can increase the depth of purple blue light penetration, accelerate the photo-crosslinking effect of corneal collagen and its efficacy. At present, the efficacy of a single wavelength system is limited by the depth of energy penetration of a single source of ultraviolet light (365 nm).

(10)‧‧‧Power supply

(11,12)‧‧‧ Panel Control Display

(13)‧‧‧Manual switch

(14)‧‧‧ Foot switch

(15)‧‧‧Power cord

(20)‧‧‧Light source

(30)‧‧‧Optical lens group

Claims (11)

An ophthalmic violet blue light therapy apparatus comprising: a light source connected to a power supply via a power cord, the power supply comprising a panel control display; a foot switch connected to the power supply; and an optical lens set, It is connected to the light source to control the spot size of the light source output light at the corneal treatment site. The ophthalmic violet blue light therapy device of claim 1, wherein the light source is an LED light source or a semiconductor laser light source, and the output light has a wavelength of 340 nm to 480 nm; the output light may be continuous light output or pulse type. The light is output at a frequency of 1 to 1,000 Hz and the output power is 3 milliwatts to 500 milliwatts at the corneal treatment site. The ophthalmic purple light therapy device of claim 1, wherein the panel control parameter comprises: an output light illumination time display, an output light power display, and an illumination mode; the illumination mode may be continuous or pulse; the pulse width is 0.001 second. Up to 2 seconds, the illumination time ranges from 60 seconds to 600 seconds. The ophthalmic violet blue light therapy device of claim 1, wherein the output light has a spot diameter ranging from 7 to 15 mm at the corneal treatment site. The ophthalmic violet blue light therapy device of claim 1, wherein the optical lens set comprises a movable position poly lens having a focal length ranging from 0.5 to 10 cm for changing a spot of the output light at the corneal treatment site. size. The ophthalmic violet blue light therapy device of claim 1, wherein the optical lens set comprises a positive lens and a negative lens of a movable position; the positive lens and the negative lens have a focal length ranging from 0.5 to 10 cm. The ophthalmic violet blue light therapy device of claim 1, wherein the output light is coupled via an optical fiber to a handle having the optical lens set built therein. The ophthalmic violet blue light therapy device of claim 1, wherein the output light is scanned to the corneal treatment site via a pair of scanning optical lens sets, the scanning diameter of which ranges from 7 to 15 mm; the scanning light should be parallel or close Parallel light, the spot diameter is 0.5 to 2.0 mm. The ophthalmic purple light therapy device of claim 1, wherein the purple light therapy device further comprises a fixing bracket; the fixing bracket comprises: a vertical and a lateral bracket, a vertical light hose bracket, or an M-shaped bracket. An ophthalmic violet blue light therapy device comprising: a single power supply connected to a single light source; or a single power supply connected to two light sources; or two power supplies connected to two light sources, respectively. The ophthalmic violet blue light therapy device of claim 10, wherein the light source output light comprises: a light having the same wavelength in a wavelength range of 340 to 480 nm; or a broad spectrum having a center wavelength of 380 to 460 nm (a spectral width of 20 to 100 nm) of the same wavelength of light; or any two different wavelengths of light in the wavelength range 340 to 480 nm.