TWM265609U - Bio- test paper using electrochemical method - Google Patents

Bio- test paper using electrochemical method Download PDF

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TWM265609U
TWM265609U TW93217464U TW93217464U TWM265609U TW M265609 U TWM265609 U TW M265609U TW 93217464 U TW93217464 U TW 93217464U TW 93217464 U TW93217464 U TW 93217464U TW M265609 U TWM265609 U TW M265609U
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groove
test paper
item
patent application
conductive film
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TW93217464U
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Chinese (zh)
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Shu-Mei Wu
Jia-Chi Wu
Jiun-Huei Bi
Chau-Wang Chen
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Taidoc Technology Corp
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M265609 八、新型說明: 【新型所屬之技術領域】 本創作相關於一種電化學生物感測試紙,尤指一種於 ::板相應於反應區處凹設有—缺口而增加吸收樣品角 度與面積的電化學生物感測試紙。 【先前技術】 =科技的進步’以前許多必須在醫院才能檢測的試 ^現"在大多走向居家贼时向,目前市面上有許多用 =人後即可丢棄且用於居家自行操作之生物感測試 =適a非專業人員及居家護理方便使用,不會有污染的 情料生,並且配合適當的生物感測器裳置,即可測量出 正確的測量數值。 萏用之電化學生物感測試紙具有一基板、一導電膜、 =應區及上隔板,在該基板上形成導電膜,該導電膜 匕含二條分離且互不相接觸的陽極部分和陰極部分,在該 導電膜上局部覆蓋一層電絕緣層而裸露出部分導電膜,該 導電膜陽極分及陰極部分裸露出之部分—端形成工作 電極及參考電極,而另_端則可與生物❹彳器連接,並在 該工作電極及參考電極上覆蓋—反應1,該反應區視不同 原,而製作,並於反應區上覆蓋上隔板。#樣品吸入後, 樣απ即會與反應區物質產生反應並產生電化學變化,而由 ,作電極與參考電極傳導至導電膜另一端之陰極接頭與 陽,接頭’藉由與生物感測器裝置連接並接收訊號,經過 計算而將訊號轉換成待測物濃度顯示。 M265609 二而,大多數試紙設計為利用毛細現象而將樣品吸入 反,區中,此時樣品吸入反應區的時間太慢時,先進入的 樣σα π已經開始與反應區試劑進行反應而導致反應不一 致,仔到一不正確的結果值,因此樣品進入反應區的時間 會影響檢測的準確性。或者,習用之試紙設計的吸入口都 設計只有一個固定方向才能吸入樣品,因此使用者必須正 確的對準財向,才能將樣品吸人反應區巾,故有待進一 步的改進。 【新型内容】 、為了改善上述習用缺失,本創作提供一種於電化學生 物感Κ紙之上隔板相應於反應區處凹設有一增加吸入 樣品角度與面積之缺口,進而增加檢測準確性。 為了達到上述目的,本創作之技術手段在於提供一 電化學生物感測試紙,其係包括-基板、-設於基板上之 ,電膜、用以進行反應並與導電膜接觸之反應區以及一覆 "反應區之上h板’遠上隔板相應於該反應區處凹設一 缺口。 本創作所述之電化學生物感測試紙中,該缺口可設於 該上隔板相應於反應區處之外側,較佳地,該缺口呈^圓 形或半橢圓形。另外,該試紙可於導電膜上覆蓋—層中隔 板,且該中隔板相應於該反應區處可凹設有一凹槽,於: 創作之-較佳實施财,該凹槽係可設於該中隔板之中段 處’呈橫向且開π向該中隔板之—側,而該中隔板於凹^ M265609 内側向凹槽開口之另—側設有—呈橫向之通氣槽,該通氣 槽可用以通氣而增加樣品吸入的速度。 另一方面,本創作所述之電化學生物感測試紙中,該 上隔板相應於中隔板之凹槽處開設有一用以通氣之開 孔,而该上隔板相應於中隔板之凹槽内侧向另一側處凹設 有-開口朝下且呈橫向之凹溝’且該凹溝連接於該開孔。 於本創作之另一較佳實施例中,本創作所述之電化學 生物感測試紙中,該中隔板相應於該反應區處凹設有一凹 槽,該凹槽係設於該中隔板之一端,呈縱向且開口向該 端,另外該中隔板於凹槽開口之另一端可設有一呈橫向而 與凹槽形成τ字型之通氣槽,該通氣槽用以增加通氣而促 進樣品吸人反應區的速度。另外’本創作所述之電化學生 物感測試紙進-步可包括—設於該導電膜與中隔板間之 絕緣層,該絕緣層相應於該中隔板凹槽處凹設有一第二凹 槽0 另外,本創作所述之電化學生物感測試紙中,該基板 相應於反應區處可設有-粗链段,該粗糖段可為複數二直 線’其係用u增加反應區物#緊密貼於基板以及導電膜 再者,本創作所述之電化學生物感測試紙中,該導電 :可具有至少三個電極’其中二個電極相連接形成短路結 冓、亥短路結構可用以啟動相符合而用以_試紙㈣結 果的生物感測器裝置。 M265609 較佳地,本創作所述之電化學生物感測試紙中,該導 電膜包括一導電銀膠層及一導電碳粉層,該導電碳粉層覆 蓋於導電銀膠層上,該導電銀膠層中段處可設有一與電極 互不相接觸之叉叉圖案,更佳地,該導電碳粉層中段處設 有一與電極互不相接觸之箭頭圖案。另外,該導電銀膠層 較佳地並未設於反應區處。 藉此,本創作之電化學生物感測試紙藉由上隔板相應 於反應區處凹設有一增加吸入角度與面積的缺口,因此可 增加樣品吸入反應區的速度,減少樣品充滿整個反應區的 時間,故,本創作之電化學生物感測試紙可增加檢測的準 確性,提高品質。 【實施方式】 請參考第-及二圖所示,其係本創作第一種實施例之 立體示意®及分解圖’摘作之f化學生物感測試紙包括 一基板(1 0 )、-導電膜(2 0 )、-中隔板(3 〇 )、 反應區、及一上隔板“〇)’該基板(1 0)可為一矩 形片體,較佳為具有電絕緣特性。 該=(20)塗佈於基板(1〇)上,且較佳地 =-導電銀膠層(22)及一導電碳粉層(24),該 導電碳粉層(2 4)覆蓋於導電銀膠層( 導電銀膠層(2 2)及導電w二)而该 導電反叔I (2 4)分別至少包含 -條電極,圖中所示為導電銀膠層( 而導電碳粉声f 9 /1、θJ '有一個電極’ (2〇)電‘之士個電極’較佳地’該導電膜 (2 0 )電極之一端呈縱向且彼此呈平行,係用以與生物 M265609 感測益相接觸偵測電化學的改變。 =m板(3 Q )覆蓋於部分基板(i Q )及導電膜 (2 〇 )、上’且裸露出導電膜(2 0 )之-端,分別用以 與生物感測器接通價測電化學的改變,該中隔板 中I又處凹。又有凹槽(32)而裸露出導電膜之另 一端。較佳地:,該凹槽(3 2 )呈橫向且開口向該中隔板 之側。為了增加樣品吸入的速度,該中隔板(3 〇 m”)内侧處連通開設有一通向另一側之通氣槽 ㈡4 )’猎由通氣槽(3 4 )的設置,即可增加通氣的 效果。較佳地,該導雷叙腴 r ” 凹_^ w 未設於相應於該 才曰(3 2 )處。另一方面,該中隔板(3 〇 )亦可由 刷方式=代,即利用印刷的方式避開反應區處印刷—層絕 緣層覆盍部分基板(1 〇 )及導電膜(2 〇 ),另外,亦 可直接省略該中隔板(3 0)或印刷絕緣層。 , 該反應區係覆蓋於中隔板(3 〇 )之凹槽㈡ 二與導電膜(20)之一端接觸,其係含有生物活性物質 (例如酵素)、酵素輔助因子、安定劑(如高分子聚人物 及緩衝溶液等’藉由中隔板(3 0)之通氣槽(3 4 )設 置而增加樣品進入反應區的時間。 該上隔板(4 0)覆蓋於中隔板(3 〇)中段上 於相應於反應區處凹設有—缺口( 4 6 ),較佳地,該缺 口( 4 6 )呈半圓形或半橢圓形,藉由缺口( 4 二 計,而增加樣品吸入反應區的面積。由於缺口( 、;: 加樣品吸入的面積,因此樣品I ^ ^ 很 俅σο不但可從側面平行試紙的方 M265609 2吸入反應區中’並且亦可由上方不同角度吸入反應區 ^故不但增加使用的方便性,並且也可增加樣品吸入的 迷度,進而增加試紙的準確性。 於本創作之較佳實施例中,本創作於該些電極相應於 反應區處之一端外側設有一粗趟段(2 6 ),較佳地,該 粗縫段(2㈠可呈-直線或複數段直線。該粗糖段(2 6 )、可為導電材質,該粗糙段(2 6 )更佳地由導電碳粉 形成’且不與導電膜(2 0 )相接觸。另外,該粗趟段(2 6 )亦可由非導電材質製作。該粗趟段(2 6 )可增加基鲁 反(10)的粗糙度,增加反應區物質貼附強度,防止反 f區物質脫落。於本創作之—較佳實施例中,該粗链段(2 位於基板(1 0 )相應於反應區處,較佳地,該粗糙 & ( 2 6 )位於近反應區外側。 於本創作之較佳實施例中,該導電膜(2 〇 )之任意 -條電極相連接形成短路’而其餘的電極分離且互不相接 觸所幵y成的紐路結構可用以啟動生物感測器裝置。另一 方面,於本創作之另一較佳實施例中,該導電銀膠層(2 # f )中段處設有一與電極互不相接觸之叉叉(2 3 )圖案, :使,者將電化學生物感測試紙正面與反面插錯時,即會 到《亥又又(2 3 )圖案’顯示該面是反面,另外,該導 層(2 4)中段處設有一與電極互不相接觸之箭頭 (2 5 )圖案,其係用以指示使用者順著箭頭(2 5 )方 =將電化學生物感測試紙插入生物感測器中,增加使用者 操作的方便性。 M265609 本創作使用時,當樣品經由毛細現象吸入,則與反應 區進行反應,而中隔板(3 0)之通氣槽(3 4) ^增: 排^ ’加速樣品吸入的㈣,因此可縮短樣品充滿反應區 的時間。樣品接觸反應區後而使得乾燥試劑溶解並進行反 應進而產生電化學的改變,經由與反應區接觸之導電膜 2 0 )電極傳導,而由生物感測器裝置連接並接收訊 號’並將訊號計算轉換成待測物漢度顯$。當電化學生物 感測試紙插設人相配合的生物感測器裝置内,藉由電 試紙導電膜(2 〇 )上二電極形成的短路結構啟 源開啟::::即可免除在使用前,需按麗生物感測器電 請^第三圖料,其係摘作之第二種實施例之示 :圖,其係大部分結構與第一種實施例相 = ^40)相應於中隔板(3〇)之凹槽(32)處 :tur(42)’其係用以通氣,更佳地,該上隔 :( = )相應於中隔板(‘30)之凹槽(32) ==凹,有一開口朝下且呈橫向之凹溝( 4連接於該開孔(42),藉由該開孔(42) 之通· Λ 林代第—種實施例的中隔板(3 0 ) 之通=(3 4),增加排氣而促進樣品吸入的速度。 0 a 板(3 〇 a )、反應區以及一上隔板(4〇 a 之示=考L四及五圖所示,其係本創作之第三種實施例 7圖,本創作之電化學生物感測試紙具有一基板(1 )、一導電膜(2〇a)、-絕緣層(50)、一中隔 該中隔板 M265609 (3 0 a )係於一端開設有呈縱向之凹槽(3 2 a ),該 凹槽(3 2 a )連通開設有一橫向的通氣槽(3 4 a )而 與凹槽(3 2 a )呈τ字型。該凹槽(3 2 a )係用以由 試紙前端吸入樣品,並藉由通氣槽(3 4 a )通氣而增加 樣品吸入速度。 該上隔板(4 0 a )相應於該凹槽(3 2 a )處凹設 有一缺口( 4 6 a ),較佳地,該缺口( 4 6 a )呈半圓 形或半橢圓形,藉由缺口( 4 6 a )的設計,而增加樣品 吸入反應區的面積。由於缺口( 4 6 a )增加樣品吸入的 面積、,因此樣品不但可從端面平行試紙的方向吸入反應區 中,並且亦可由上方不同角度吸入反應區中,故不但增加 使用的方便性’並且也可增加樣品吸入的速度,進而增加 試紙的準確性。 、、又,5亥絕緣層(5 〇 )覆蓋於導電膜(2 0 a )上, 並裸路出導電臈(2 〇 a )之—端,並於相應於該中隔板 (^ 〇 a )之凹槽(3 2 a )處凹設有一第二凹槽(5 2 ), 其係用以覆i反應區,而令該反應區與導電膜(2 〇 a ) 之一端接觸。 :該導電膜(20a)之外側設有一與基板(i〇a) I:附於C糙段(2 6 a ),其係用以增加反應區物質 、r二反1 0 a )上,並且具有阻擋效果,而可防止 ==外側脫落,尤其在裁切時,容易形成較大的 雁广^ 紙’藉由所設之粗糙段(26 a)而防止反 應區物質脫落。 M265609 綜上所述,本創作之電化學生物感測試紙藉由於上p 板上相應於反應區處凹設有一缺口而增加樣品吸入反: 區的角度與面積,增加試紙使用的容易性,並且增加樣口: 吸入反應區的速度,故而可增加檢測的準確性。θ 7 °口 *雖然前述實舰明賴作之具體事實,但應瞭解 可能的修正及改變均不悖離以τ主張之申請 精神及範疇。 祀圍的 【圖式簡單說明】M265609 8. Description of the new type: [Technical field to which the new type belongs] This creation is related to an electrochemical biosensor test paper, especially a kind of: a plate that is recessed in the reaction area corresponding to a-gap to increase the angle and area of the sample being absorbed. Electrochemical biosensor test paper. [Previous technology] = Advances in technology. 'Many previous tests that can only be detected in hospitals are now available.' Most of them go to home thieves. At present, there are many uses in the market that can be discarded after being used by people and used for home operations. Biosensing test = suitable for non-professionals and home care, it is easy to use, there will be no contamination, and with the appropriate biosensor dress, you can measure the correct measurement value. The electrochemical biosensor test paper used has a substrate, a conductive film, an application area, and an upper separator. A conductive film is formed on the substrate. The conductive film contains two separate anode portions and a cathode that are not in contact with each other. Part of the conductive film is partially covered with an electrically insulating layer to expose part of the conductive film. The exposed part of the anode and cathode of the conductive film-the end forms the working electrode and the reference electrode, and the other end can be connected with the biological The pottery is connected, and the working electrode and the reference electrode are covered—Reaction 1. The reaction zone is made according to different sources, and a separator is covered on the reaction zone. #After the sample is inhaled, the sample απ will react with the substance in the reaction zone and generate an electrochemical change, and the electrode and reference electrode are conducted to the cathode connector and the anode at the other end of the conductive film. The connector is connected to the biosensor by The device is connected and receives the signal, and the signal is converted into the concentration of the analyte to be displayed after calculation. M265609 Secondly, most test strips are designed to suck the sample into the reverse zone using capillary phenomenon. At this time, when the sample is sucked into the reaction zone too slowly, the sample σα π which has entered first has begun to react with the reagent in the reaction zone and cause the reaction Inconsistent, an incorrect result value, so the time that the sample enters the reaction zone will affect the accuracy of the test. Alternatively, the conventional test paper design of the suction port is designed to suck the sample only in a fixed direction, so the user must correctly align the financial direction to suck the sample into the reaction zone towel, so further improvement is needed. [New content] In order to improve the above-mentioned conventional defects, the present invention provides a gap above the electrochemical biosensory K paper corresponding to the reaction zone with a notch that increases the angle and area of the sample to be sucked, thereby increasing detection accuracy. In order to achieve the above purpose, the technical means of this creation is to provide an electrochemical biosensing test paper, which includes-a substrate,-an electric film provided on the substrate, a reaction zone for performing a reaction and contacting the conductive film, and a A "h-plate" covering the "reaction zone" is formed with a notch corresponding to the reaction zone. In the electrochemical biosensing test paper described in this creation, the notch may be provided on the outer side of the upper partition corresponding to the reaction zone. Preferably, the notch is round or semi-elliptical. In addition, the test paper can be covered on the conductive film-a middle spacer, and the middle spacer can be recessed with a groove corresponding to the reaction zone. At the middle section of the middle partition plate, it is transverse and opens π to the side of the middle partition plate, and the middle partition plate is provided on the other side of the opening of the recess ^ M265609 to the groove, which is a lateral ventilation groove, The vent can be used to increase the rate of sample inhalation. On the other hand, in the electrochemical biosensing test paper described in this creation, an opening for ventilation is provided in the upper partition corresponding to the groove of the middle partition, and the upper partition corresponds to the middle partition. A groove is formed on the inner side of the groove to the other side, and the groove is opened downward and horizontal, and the groove is connected to the opening. In another preferred embodiment of the creation, in the electrochemical biosensory test paper described in the creation, a groove is recessed in the middle partition corresponding to the reaction area, and the groove is provided in the partition. One end of the plate is longitudinal and opens to the end. In addition, the middle partition plate may be provided with a vent groove in a transverse direction and forming a τ-shape with the groove at the other end of the groove opening. The vent groove is used to increase ventilation and promote The rate at which the sample is drawn into the reaction zone. In addition, the step of the electrochemical biosensor test paper described in this creation may include-an insulating layer provided between the conductive film and the middle partition plate, and the insulating layer corresponding to the groove of the middle partition plate is provided with a second recess Groove 0 In addition, in the electrochemical biosensing test paper described in this creation, the substrate may be provided with a -coarse segment corresponding to the reaction zone, and the crude sugar segment may be a plurality of straight lines.物 # is closely attached to the substrate and the conductive film. Furthermore, in the electrochemical biosensor test paper described in this creation, the conductivity: may have at least three electrodes, two of which are connected to form a short-circuit junction, and a short-circuit structure is available In order to activate the biosensor device that is used to test the test results. M265609 Preferably, in the electrochemical biosensing test paper described in this creation, the conductive film includes a conductive silver adhesive layer and a conductive carbon powder layer, and the conductive carbon powder layer covers the conductive silver adhesive layer, and the conductive silver A cross pattern that is not in contact with the electrodes may be provided at the middle portion of the adhesive layer. More preferably, an arrow pattern is not provided in the middle of the conductive carbon powder layer that is not in contact with the electrodes. In addition, the conductive silver glue layer is preferably not provided at the reaction area. With this, the electrochemical biosensor test paper created by the upper plate corresponding to the reaction zone is recessed with a gap to increase the suction angle and area, so the speed of the sample into the reaction zone can be increased, and the sample filling the entire reaction zone can be reduced. As a result, the electrochemical biosensor test paper of this creation can increase detection accuracy and improve quality. [Embodiment] Please refer to the first and second figures, which are three-dimensional illustrations and exploded views of the first embodiment of this creation. The abstracted chemical biological sensing test paper includes a substrate (1 0),-conductive The film (20),-the middle spacer (30), the reaction zone, and an upper spacer "0) 'The substrate (10) may be a rectangular plate, preferably having electrical insulation properties. This = (20) coated on the substrate (10), and preferably = conductive silver glue layer (22) and a conductive carbon powder layer (24), the conductive carbon powder layer (24) covering the conductive silver glue Layer (conducting silver glue layer (2 2) and conductive w 2), and the conductive anti-tertiary I (2 4) each contains at least one electrode, the conductive silver glue layer is shown in the figure (and the conductive carbon powder sound f 9 / 1. θJ 'has an electrode' (2〇) electrical 'single electrode' preferably 'one end of the conductive film (20) electrode is longitudinal and parallel to each other, which is used to be beneficial to the biological M265609 sensing Electrochemical changes are detected by contact. = M plate (3 Q) covers part of the substrate (i Q) and conductive film (20), the top of the conductive film (20) is exposed, and is used to communicate with Biosensor On Price As measured by electrochemical changes, I in the middle separator is recessed again. There is a groove (32) and the other end of the conductive film is exposed. Preferably: the groove (3 2) is transverse and the opening is toward the The side of the middle baffle. In order to increase the speed of sample inhalation, a vent groove) 4) is connected to the inner side of the middle baffle (30m ") to the other side. You can increase the effect of ventilation. Preferably, the guide ray r ″ _ _ w is not set at a position corresponding to the genius (3 2). On the other hand, the middle partition (30) can also be replaced by a brushing method, that is, using The printing method avoids the printing-layer insulation layer covering part of the substrate (100) and the conductive film (20) at the reaction zone. In addition, the middle separator (30) or the printed insulation layer can also be omitted directly. The reaction zone covers the groove of the middle partition plate (30). The second area is in contact with one end of the conductive film (20). It contains bioactive substances (such as enzymes), enzyme cofactors, and stabilizers (such as polymers) And buffer solution, etc. The time for the sample to enter the reaction zone is increased by setting the vent groove (34) of the middle partition (30). The upper partition (40) covers the middle of the middle partition (30). A notch (4 6) is recessed corresponding to the reaction zone. Preferably, the notch (4 6) has a semi-circular or semi-elliptical shape. The gap of the sample into the reaction zone is increased by the gap (4 2). Area. Because the gap (,;: plus the area where the sample is sucked in, sample I ^ ^ is very 俅 σο not only can be tested in parallel from the side Fang M265609 2 is sucked into the reaction zone 'and can also be sucked into the reaction zone from different angles from above ^ Therefore, it not only increases the convenience of use, but also increases the ambiguity of the sample inhalation, thereby increasing the accuracy of the test paper. In the embodiment, a thick section (2 6) is provided on the outer side of the electrodes corresponding to one end of the reaction zone. Preferably, the thick stitch section (2㈠ can be a straight line or a plurality of straight lines. The coarse sugar section). (2 6) may be conductive material, the rough section (2 6) is more preferably formed of conductive carbon powder and does not contact the conductive film (20). In addition, the rough section (2 6) may also be made of It is made of non-conductive material. The rough section (2 6) can increase the roughness of the Kiriu anti- (10), increase the material attachment strength of the reaction zone, and prevent the anti-f-zone material from falling off. In this creation—the preferred embodiment The thick segment (2 is located at the substrate (1 0) corresponding to the reaction zone, preferably, the rough & (2 6) is located near the outside of the reaction zone. In a preferred embodiment of the present invention, the conductive film (2) any-the electrodes are connected to form a short circuit, and the remaining electrodes The button structure formed by being separated from each other can be used to activate the biosensor device. On the other hand, in another preferred embodiment of the present invention, the middle portion of the conductive silver glue layer (2 # f) There is a fork and fork (2 3) pattern that is not in contact with the electrode. When the front and back sides of the electrochemical biosensor test paper are inserted incorrectly, the "Haiyou (2 3) pattern 'will display this The side is the reverse side. In addition, an arrow (2 5) pattern that is not in contact with the electrode is provided at the middle portion of the guide layer (24), which is used to instruct the user to follow the arrow (2 5). The biosensor test paper is inserted into the biosensor to increase user convenience. M265609 In this creative use, when the sample is inhaled through the capillary phenomenon, it reacts with the reaction zone, and the ventilation slot (3 4) of the middle partition (30) increases: row ^ 'accelerates the sample inhalation, so it can shorten Time that the sample fills the reaction zone. After the sample contacts the reaction zone, the dry reagent is dissolved and reacted to generate an electrochemical change. Conducted through the conductive film 20) electrode in contact with the reaction zone, the biosensor device is connected and receives the signal and calculates the signal. It is converted into the UUT and the display is $. When the electrochemical biosensor test paper is inserted into a human-compatible biosensor device, the short-circuit structure formed by the two electrodes on the conductive film (20) of the electric test paper is turned on and turned on :::: Please refer to the third picture of the Lai Biosensor, which is an illustration of the second embodiment: the diagram, most of which is the same as the first embodiment = ^ 40) corresponds to the medium The groove (32) of the partition plate (30): tur (42) 'It is used for ventilation. More preferably, the upper partition: (=) corresponds to the groove (32) of the middle partition plate ('30) ) == concave, there is a concave groove (4 connected to the opening (42) with the opening downward and lateral), through the opening (42) · Λ Lindai first embodiment of the middle partition plate ( The pass of 3 0) = (3 4), increase the exhaust rate and promote the speed of sample inhalation. 0 a plate (30a), the reaction zone and an upper partition (shown in 40a = test L four and five) As shown in the figure, it is the third embodiment 7 of this creation. The electrochemical biosensor test paper of this creation has a substrate (1), a conductive film (20a), an insulating layer (50), and a medium. The middle partition M265609 (3 0 a) is open at one end There is a longitudinal groove (3 2 a), and the groove (3 2 a) communicates with a horizontal vent groove (3 4 a) and is τ-shaped with the groove (3 2 a). The groove ( 3 2 a) is used to suck the sample from the front end of the test paper, and increase the sample suction speed by venting through the ventilation slot (3 4 a). The upper partition (40 0 a) corresponds to the groove (3 2 a) The recess is provided with a gap (46a). Preferably, the gap (46a) is semi-circular or semi-ellipsoidal. By designing the gap (46a), the area of the sample suction reaction area is increased. Because the gap (46a) increases the area of sample suction, the sample can be drawn into the reaction zone not only from the direction parallel to the end of the test strip, but also into the reaction zone from different angles from above, so it not only increases the convenience of use ', but also Can increase the speed of sample inhalation, thereby increasing the accuracy of the test paper. ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, And a second groove (5 2) is recessed at a groove (3 2 a) corresponding to the middle partition plate (^ 〇a), It is used to cover the i-reaction zone, so that the reaction zone is in contact with one end of the conductive film (20a). The outer side of the conductive film (20a) is provided with a substrate (ioa) I: attached to the C-rough The segment (2 6 a) is used to increase the material in the reaction zone, r 2 inverse 1 0 a), and has a blocking effect, and can prevent == outside falling off, especially when cutting, it is easy to form a large goose The paper can prevent the material in the reaction zone from falling off by the rough section (26 a). M265609 In summary, the electrochemical biosensing test paper of this creation increases the sample suction due to a recess in the upper p plate corresponding to the recess in the reaction zone: the angle and area of the zone increase the ease of use of the test paper, and Increasing the sample port: Aspiration rate into the reaction zone can increase the accuracy of detection. θ 7 ° mouth * Although the foregoing actual ship relies on specific facts, it should be understood that possible amendments and changes do not depart from the spirit and scope of the application claimed by τ. [Simplified illustration of the diagram]

第一圖係本創作第一種實施例之立體示意圖。 第一圖係本創作第一種實施例之立體分解圖。 第三圖係本創作第二種實施例之立體分解圖。 第四圖係本創作第三種實施例之立體示意圖。 第五圖係本創作第三種實施例之立體分解圖。 【主要元件符號說明】The first diagram is a three-dimensional schematic diagram of the first embodiment of this creation. The first picture is a three-dimensional exploded view of the first embodiment of this creation. The third figure is a three-dimensional exploded view of the second embodiment of this creation. The fourth figure is a three-dimensional schematic diagram of the third embodiment of the present invention. The fifth diagram is a three-dimensional exploded view of the third embodiment of the present invention. [Description of main component symbols]

^ 1 〇 Μ 1 〇 a )基板 (2〇)(2〇a)導電膜 (2 2 )導電銀膠層 (2 3 )叉又 (24)導電碳粉層 (2 5 )箭頭 (26)(26 a)粗糙段 (3 〇 ) ( 3 〇 a )中隔板 (32)(32a)凹槽 (3 4 )( 3 4 a )通氣槽 12 M265609 (40)(40 a)上隔板 (4 2 )開孔 (4 4 )凹溝 (46)(46a)缺口 (5 0 )絕緣層 (5 2 )第二凹槽^ 10 〇 10) substrate (20) (20a) conductive film (2 2) conductive silver glue layer (2 3) fork and (24) conductive toner layer (2 5) arrow (26) ( 26 a) In the rough section (30) (30a), the partition (32) (32a) groove (3 4) (3 4 a) vent groove 12 M265609 (40) (40 a) upper partition (4 2) Opening (4 4) Groove (46) (46a) Notch (50) Insulating layer (52) Second groove

1313

Claims (1)

M265609 九、申請專利範圍: 1 · 一種電化學生物感測試紙,其係包括一基板、一 設於基板上之導電膜、用以進行反應並與導電膜接觸之反 應區以及一覆蓋反應區之上隔板,其改良在於: 该上隔板相應於該反應區處凹設有一缺口。 2 ·如申請專利範圍第1項所述之電化學生物感測試 紙’其中該缺口設於該上隔板相應於反應區處之外側。 3 ·如申請專利範圍第1項所述之電化學生物感測試 紙,其中該缺口呈半圓形。 4 ·如申請專利範圍第丄項所述之電化學生物感測試 紙’其中該缺口呈半橢圓形。 5 ·如申請專利範圍第1項所述之電化學生物感測試 紙進一步包括一介於上隔板以及導電膜間之中隔板,該中 隔板覆蓋於部分基板及導電膜上,且裸露出導電膜之一 端,且該中隔板相應於該反應區處凹設有一凹槽,該凹槽 係設於該中隔板之中段處,呈橫向且開口向該中隔板之一 側。 6 ·如申請專利範圍第5項所述之電化學生物感測試 紙,其中該中隔板於凹槽内側向凹槽開口之另一側設有一 呈橫向之通氣槽。 7 ·如申請專利範圍第5項所述之電化學生物感測試 紙,其中該上隔板相應於中隔板之凹槽處開設有一用以通 氣之開孔。 M265609 8 ·如中請專利範圍第7項所述之電化學生物感測試 紙,其中該上隔板相應於中隔板之凹槽内側向另一側處凹 設有-開Π朝下且呈橫向之凹溝,且該凹溝連接於 孔。 J 9.如申請專圍第i項所述之電化學生物感測試 紙進-1包括-介於上隔板以及導電膜間之中隔板,該中 隔板覆蓋於部分基板及導電膜上,且裸露出導電膜之一 端,且該中隔板相應於該反應區處凹設有一凹槽,該凹槽 係设於該中隔板之一端,呈縱向且開口向該端。 1 0 ·如申請專利範圍第9項所述之電化學生物感測 試紙,其中該中隔板於凹槽一端設有一呈橫向而與凹槽形 成T字型之通氣槽。 一1 1 ·如申請專利範圍第i0項所述之電化學生物感 4 °式、’氏進步包括一設於該導電膜與中隔板間之絕緣 k °亥、、邑、’’彖層相應於該中隔板凹槽處凹設有一第二凹槽。 1 2·如申請專利範圍第1至丄i項任一項所述之電 化學生物感測試紙,其中該基板相應於反應區處設有一粗 糙段。 、、1 3 ·如申請專利範圍第丄2項所述之電化學生物感 測試紙,其中該粗縫段為複數段直線。 、一 1 4 ·如申請專利範圍第1 2項所述之電化學生物感 則忒紙,其中該導電膜具有至少三個電極,其中二個電極 相連接形成短路結構。 15 M265609 1 5 .如中請專利範圍第丄2項所述之電 測試紙,#中該導電臈包括—導電銀膠層及 層,該導電碳粉層覆蓋於導電銀膠層上。 1 丄b ·如申請專利範圍第丄5項所述之 測試紙,其中該導電銀膠層中段 :丄 觸之又又圖案。 i肖電極互不相接 1 7 ·如申請專利範圍第1 6頊斯、+、 _ 測兮祕甘丄 0貝所迷之電化學生物感 K式紙,其中該導電碳粉層中段處嗖右t 觸之箭頭圖案。 叹有一與電極互不相接 十、囷式: 如下頁。M265609 IX. Patent application scope: 1 · An electrochemical biosensing test paper, which includes a substrate, a conductive film provided on the substrate, a reaction area for performing a reaction and contacting the conductive film, and a covering area of the reaction area The upper partition board is improved by: a recess is formed in the upper partition board corresponding to the reaction zone. 2. The electrochemical biosensor test paper according to item 1 of the scope of the patent application, wherein the gap is provided on the outer side of the upper partition corresponding to the reaction zone. 3. The electrochemical biosensor test paper according to item 1 of the patent application scope, wherein the gap is semicircular. 4 · The electrochemical biosensor test paper as described in item 丄 of the patent application range, wherein the gap is semi-elliptical. 5 · The electrochemical biosensor test paper according to item 1 of the patent application scope further includes an intermediate separator between the upper separator and the conductive film, and the intermediate separator covers part of the substrate and the conductive film and is exposed. One end of the conductive film, and the middle partition plate is recessed with a groove corresponding to the reaction area, and the groove is provided at the middle of the middle partition plate, and it is transverse and opens to one side of the middle partition plate. 6. The electrochemical biosensor test paper according to item 5 of the scope of the patent application, wherein the middle partition plate is provided with a lateral ventilation groove on the inner side of the groove toward the other side of the opening of the groove. 7 · The electrochemical biosensor test paper according to item 5 of the scope of the patent application, wherein the upper partition corresponds to a recess in the middle partition with an opening for ventilation. M265609 8 · The electrochemical biosensing test paper as described in item 7 of the Chinese Patent Application, wherein the upper partition is recessed to the other side corresponding to the inside of the groove of the middle partition, and the opening is facing downward and showing A horizontal groove, and the groove is connected to the hole. J 9. The electrochemical biosensor test paper feed as described in the application section i-1 includes-an intermediate separator between the upper separator and the conductive film, and the intermediate separator covers part of the substrate and the conductive film One end of the conductive film is exposed, and the middle partition plate is recessed with a groove corresponding to the reaction area. The groove is provided at one end of the middle partition plate and has a longitudinal direction and an opening toward the end. 10 · The electrochemical biosensing test paper according to item 9 of the scope of the patent application, wherein the middle partition is provided at one end of the groove with a vent groove which is transverse and forms a T-shape with the groove. 1 1 · The electrochemical biosensing 4 ° formula, as described in item i0 of the scope of patent application, includes a dielectric layer between the conductive film and the middle partition, a layer, and a layer. A second groove is recessed corresponding to the groove of the middle partition plate. 12. The electrochemical biosensor test paper according to any one of claims 1 to 范围 i, wherein the substrate is provided with a rough section corresponding to the reaction zone. 1, 3 · The electrochemical biosensor test paper according to item 2 of the scope of the patent application, wherein the thick seam section is a plurality of straight lines. 1, 1 · The electrochemical biosensor paper as described in item 12 of the patent application scope, wherein the conductive film has at least three electrodes, and two of the electrodes are connected to form a short-circuit structure. 15 M265609 1 5. The electrical test paper described in item 2 of the patent scope, the conductive pad in # includes-a conductive silver adhesive layer and a layer, and the conductive carbon powder layer covers the conductive silver adhesive layer. 1 丄 b · The test paper as described in item 丄 5 of the scope of patent application, wherein the middle section of the conductive silver adhesive layer: 图案 touches another pattern. The Xiao electrodes are not connected to each other. 1 · For example, the scope of the application for the patent No. 16 顼, +, _ Measure the electrochemical biosensory K-type paper, which is contained in the middle of the conductive carbon powder layer. Right t-touch arrow pattern. Sigh there is no connection with the electrodes. Ten, style: See the following page.
TW93217464U 2004-11-02 2004-11-02 Bio- test paper using electrochemical method TWM265609U (en)

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